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Vol 12 (2013) - today
Vol 11 (2012)
Prognostic value of low skeletal muscle mass in hepatocellular carcinoma patients treated with sorafenib or lenvatinib: A meta-analysis
Article - PDF
Published: Jan 4, 2021
DOI: https://doi.org/10.17179/excli2020-3111
low skeletal muscle mass, sorafenib, lenvatinib, hepatocellular carcinoma, prognosis
Jun Guan
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Qin Yang
Chao Chen
Haihong Zhu
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, NO.79 Qingchun Road, Hangzhou, Zhejiang, China. Phone: +86-571-87236579, E-mail: Zhuhh72@zju.edu.cn
Growing evidence indicates that skeletal muscle depletion has a notable effect on the prognosis of hepatocellular carcinoma (HCC) patients, though study results are still controversial. Our meta-analysis aimed at evaluating the prognostic significance of low skeletal muscle mass (LSMM) in HCC patients treated with sorafenib or lenvatinib.We systematically reviewed for PubMed, Cochrane, and Embase databases from their inception to August 2020 and obtained all relevant articles describing an association between LSMM and HCC patients treated with sorafenib or lenvatinib. Demographic and characteristics of included studies, diagnostic criteria of skeletal muscle depletion, and main outcomes (overall survival, progression-free survival, time to treatment failure) were retrieved. Associations were expressed by calculating hazard ratios (HRs) and 95 % confidence intervals (CIs).The meta-analysis enrolled 11 studies comprising 1148 patients. Without significant heterogeneity between studies, LSMM was significantly associated with poor overall survival (crude HR=1.58, 95 % CI: 1.36–1.83; adjusted HR=1.83, 95 % CI: 1.46–2.29) and time to treatment failure (crude HR=1.85, 95 % CI: 1.34–2.54; adjusted HR=1.72, 95 % CI: 1.24–2.38). However, there was no significantly association between LSMM and progression-free survival (adjusted HR=1.44, 95 % CI: 0.95–2.20). Symmetry of distribution on the funnel plot did not show significant publication bias.This meta-analysis supported that LSMM is significantly associated with poor overall survival and time to treatment failure in HCC patients after sorafenib or lenvatinib administration. This negative effect was pronounced even after adjustment for confounders. Future studies should be carried out on larger samples and study regions based on standardized thresholds of LSMM.
Guan, J., Yang, Q., Chen, C., Wang, G., & Zhu, H. (2021). Prognostic value of low skeletal muscle mass in hepatocellular carcinoma patients treated with sorafenib or lenvatinib: A meta-analysis. EXCLI Journal, 20, 1-16. https://doi.org/10.17179/excli2020-3111
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Ping Wang, Wengui Xu, Jian Sun, Chengwen Yang, Gang Wang, Yu Sa, Xin-Hua Hu, Yuanming Feng, A new assessment model for tumor heterogeneity analysis with [18]F-FDG PET images , EXCLI Journal: Vol. 15 (2016)
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Articles published in EXCLI Journal are licensed under a Creative Commons Attribution 4.0 International License.
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Dubai FAQs
Support Groups & Charities
Maids & Home Help
Working In Dubai
Advertise A Job Vacancy
University & Colleges
After School Activities and Learning Support
Business Set Up
Relocation & Removals
Driving in Dubai
Fitness & Slimming
Free Covid-19 Vaccine in Dubai: What Is It and Where To Get It
Is Pepper Spray Allowed in Dubai? A Guide for Expats
How You Can Donate Food, Clothes, Toys, and Furniture in the UAE
The Best Abandoned Places in the UAE You Can Explore Right Now
How to Get a 5-Year Retirement Visa in Dubai: Guide for Expats
5 Ways to Make Your Late-Night Flight More Bearable
5 of the Most Beautiful Golf Courses Around the World
Tourists Can Now Get SIM Cards When Landing in Dubai
All Credits: PA
The Latest Big Online Debate: Who Gets to Use the Armrests on a Plane?
UAE Allows 100% Ownership of Businesses by Foreign Nationals
All About Dubai's New Residency Visa For Remote Workers
Job Searching in the UAE: Should I Tell an Interviewer I'm Pregnant?
UAE Gives Equal Pay for Women and Men in the Private Sector
The Right Way to Use Networking to Get a Job
Why We Should All Be Practising ‘Inbox Mindfulness’ To Reduce Stress At Work
Picture: Supplied | Adjusting to work is easy with these top tips
Expert Tips on Working From Home
6 Signs That You Might Have Work Separation Anxiety
5 Things Nobody Tells You About the Reality of Going Freelance
Tickets Now on Sale for This Year's Emirates Airline Festival of Literature
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Women’s Voices You Can’t Ignore: Bolu Babalola at the Emirates Airline Festival of Literature
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Meet Nobel Prize Winner Malala at the Emirates Airline Festival of Literature 2021
Women’s Voices You Can’t Ignore: Malala at the Emirates Airline Festival of Literature
Big Names Announced for the Emirates Airline Festival of Literature 2021
It's Official: UAE Joins Top 10 Most Influential Countries in the World
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Meet Digital Entrepreneur Victoria Montgomery Brown at the Emirates Literature Festival
It's Twice the Fun for Foundation Friends at This Year’s Emirates Airline Festival of Literature
UAE Issues New Procedures for Residents Returning to the Country
A Peek Inside Dubai's Extraordinary Boarding School Facilities
7 Questions to Ask Before Applying for a Dubai University
How To Reinvent Your Child's Learning For the Modern World
The IB Diploma Programme: An Advantage for University Admissions?
10 Tips for Choosing the Right School For Your Child in Dubai
List of Approved UAE School Holidays for 2020/2021
The Wonders of the Bilingual Brain: Interview With Christiana Gonzalez
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5 Things You Should Know Before Applying For Your First Credit Card
5 Credit Card Benefits That Makes Them Financial Must Haves
How to Get the Most From Your Credit Card Rewards in Dubai
6 Questions to Ask Yourself Before Applying for a New Credit Card
4 Biggest Perks of Paying With a Credit Card
5 Ways to Use Credit Card Rewards to Your Advantage
Hand Sanitizers, Face Masks, and Gloves Now VAT Free in the UAE
Everything You Need for a Movie Night at Home in Dubai
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Pet Grooming and Pampering Services in Dubai Starting From AED 49
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Find yourself accumulating a fair bit of stuff? Here are some ways you can donate the things you no longer need in the UAE
| Last updated on 8 September 2020
Donate food and second-hand goods with our complete list of UAE charities and non-profit organisations
If you have been an expat in the UAE for more than a few seasons, you may have already noticed the build-up of clothes, furniture, toys, food, books, and other items that have been grown out of or are simply not needed anymore. From time to time, it's necessary to clear things out... and figuring out how is often easier said than done.
While you can easily chuck your used goods in with the garbage, there are a number of more environmentally friendly options out there as well as services that can pass along your unwanted items to those who will find them useful.
To start, we've compiled a handy list of UAE charities and non-profit organisations to help you find a new home or owner for your second-hand donations.
Dubai Cares
Dubai Cares accepts donations for second-hand clothing for both children and adults. During their annual Ramadan Campaign or in times of crisis faced by other countries, you'll find their telltale donation boxes in shopping malls. They are also open for volunteer work and other forms of support.
For more information, call 04 450 4550 or visit www.dubaicares.ae
Beit Al Khair Society
Another place to donate used items in the UAE is at Beit Al Khair Society, where you can pass along furniture, toys, clothes, etc. that you don't want anymore. They have various locations, but the biggest branch is near NMC Hospital, Al Nahda in Dubai.
For more information, call 04 267 5555 or visit http://beitalkhair.org/en/
Emirates Red Crescent
The Emirates Red Crescent is a great volunteer-run humanitarian organisation. They will gladly accept secondhand clothes, bedding, and other goods, of which they will provide to other countries that are facing a crisis such as war, natural disasters, etc. They do not pick-up items, but you can find their donation boxes and representatives in various locations across Dubai and Abu Dhabi.
For more information, call 800733 or visit www.rcuae.com
Rags to Riches
Originally founded by Barbara Evans, Rags to Riches is now managed by Ceri Rocca in Dubai and Fahmida Seitz in Abu Dhabi, along with a team of dedicated volunteers. They accept donations in the UAE for blankets, bed linen, curtains, and towels and make new clothing as well as reusable sanitary products from those. Rags to Riches has several drop-off locations across the UAE and are pretty active on social media.
For more information, contact [email protected] or visit their Facebook page: https://www.facebook.com/Rags2RichesUAE/
Maria Christina Foundation
Located along Sheikh Zayed Road in Sky Tower, the Maria Christina Foundation happily accepts a variety of donations such as old clothes, blankets, shoes, and even furniture. To donate unwanted furniture in Dubai, this must be arranged and will usually be no problem as they have teams in Mirdiff, Umm Suquem, and Bur Dubai. Proceeds from their sales go as relief aids for the poor and needy in developing or poverty-stricken countries.
For more information, visit www.mariacristinafoundation.org
The Old Library is a popular second-hand bookstore in Dubai, located in the Gold and Diamond Park. You can donate books in Dubai here, such as used textbooks, novels, etc. so long as they are in good condition.
For more information, call 04 321 3939 or visit https://www.theoldlibrary.ae/
Dar Al Ber Society
If you're looking for a place to donate unused, pre-owned medicines in the UAE, look to Dar Al Ber Society. As long as the medicines have not been used, are sealed, and have not yet expired, they will gladly accept such charitable donations. Dar Al Ber Society also accepts used clothes, household items including furniture, and other forms of support. All of these are collected to provide for orphans in the UAE, the needy, and low-income households in other parts of the world.
For more information, visit https://daralber.ae/cms/en/
Dubai Health Authority
Another organisation you can donate pre-owned, unopened, and even expired medicines are at Dubai Health Authority pharmacies, clinics, hospitals, and other healthcare centres in the emirate - except the Rashid and Latifa hospitals. The expired medicines will be properly disposed by staff, and unopened and unexpired medicines will be verified before being donated to the needy.
For more information, visit www.dha.gov.ae
Al Ihsan Charity
Al Ihsan Charity accepts charitable collections such as second-hand clothing, shoes, furniture, kitchenware, food, school supplies, unused medicine, etc. for families who have lost their only breadwinner through death, deportation, a jail sentence, they've been abandoned, divorced, etc. to help them get back on their feet.
For more information, visit www.alihsan.ae
Take My Junk
The name says it all. Take My Junk collects second-hand "junk" that you no longer want and distributes them to people in need. This organisation will accept nearly anything for donation, and also offer a free pick-up service for your used goods such as furniture, appliances, kitchenware, and other household items. Simply send them an SMS at 056 808 5865 to arrange a pick-up.
For more information, visit https://www.takemyjunkuae.com/
K9 Friends
For donating unwanted pet food and other pet supplies, head to K9 Friends, the UAE's longest-running pet rescue and rehoming shelter. Doing so would help the volunteer team care for the rescued animals until the pets find a new loving home, as the shelter would often receive more rescued dogs and cats than it can hold.
For more information, call 04 8878739 or visit http://www.k9friends.com/
Dubai Center for Special Needs
Any unwanted household goods, clothes, toys, and footwear can be donated to Dubai Center for Special Needs, located in Al Karama. All items collected from donations will be sold, and proceeds raised will go into relief aid for special needs families in the UAE.
For more information, visit http://dcsneeds.com/
Al Noor Special Needs Training Centre
The Al Noor Special Needs Training Centre is supported by His Highness Sheikh Mohammed bin Rashid Al Maktoum, the Ruler of Dubai. The organisation works to promote the development and well-being of children and adults who face physical and cognitive challenges. On top of offering training, programs, and activities, the centre has a wide selection of therapy available for people with special needs. The Al Noor Special Needs Training Centre relies on charity and sponsorship, so UAE residents are encouraged to donate second-hand goods here. The Al Barsha branch in Dubai accepts donations for second-hand clothes.
For more information, visit https://alnoorspneeds.ae/
where to donate in UAE
donating to others
ON EXPATWOMAN TODAY
Doctors, Engineers and Students Can Now Apply for 10 Year UAE Visa
Living Together Unmarried in the UAE is Now Allowed
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Covid-19 Vaccine in the UAE Has Been Granted Emergency Approval
About Al Hosn, The App That Tracks COVID-19 Cases in UAE
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Singapore is a cultural city and has an array of museums ranging from history to art and everything in between.
National Museums
Asian Civilisations Museum (ACM)
1 Empress Pl, Singapore 179555
www.acm.org.sg
The Asian Civilisations Museum is an institution which forms a part of the four museums in Singapore, the other three being the other Asian Civilisations Museum at Old Tao Nan School, the National Museum of Singapore and the Singapore Art Museum.
Peranakan Museum
39 Armenian St, Singapore 179941
www.peranakanmuseum.org.sg
The Peranakan Museum is a museum in Singapore specialising in Peranakan culture.
National Museum of Singapore
93 Stamford Rd, Singapore 178897
www.nationalmuseum.sg
The National Museum of Singapore is a national museum in Singapore and the oldest museum in Singapore.
Singapore Art Museum (SAM)
71 Bras Basah Rd, Singapore 189555
www.singaporeartmuseum.sg
The Singapore Art Museum – SAM contains the national contemporary art collection of Singapore. SAM is home to the world’s largest public collection of modern and contemporary Southeast Asian artworks, with a growing collection of international contemporary art.
8Q SAM
8 Queen St, Singapore 188535
www.singaporeartmuseum.sg/visitus
SAM at 8Q is a museum for contemporary art in Singapore, located at the heart of the city. It is an extension of the Singapore Art Museum (SAM), with its name deriving from the museum's location at No. 8 Queen Street near Bras Basah Road.
ArtScience Museum (Marina Bay Sands)
www.marinabaysands.com/museum.htm
Baba House (National University of Singapore)
157 Neil Rd, Singapore 088883
www.nus.edu.sg/cfa/museum/about.php
The Battle Box
2 Cox Terrace, Singapore 179622
mail.legendsfortcanning.com/aboutus_battlebox.html
Fort Siloso (Sentosa)
33 Allanbrooke Road Sentosa, Singapore 099981
www.sentosa.com.sg
Fuk Tak Chi Museum
76 Telok Ayer St, Singapore 048464
en.wikipedia.org/wiki/Fuk_Tak_Chi_Museum
Images of Singapore (Sentosa)
40 Imbiah Rd, Singapore 099700
www.sentosa.com.sg/en/attractions/imbiah.../images-of-singapore/
Maritime Experiential Museum & Aquarium (Sentosa)
8 Sentosa Gateway, Resorts World Sentosa, Singapore 098269
www.rwsentosa.com
Mint Museum of Toys
www.emint.com
The Mint Museum of Toys is the world's first purpose-built museum for toys, which showcases a private collection of vintage toys, including rare and unique one-of-a-kind pieces from around the world.
NUS Museum (National University of Singapore)
www.nus.edu.sg/museum
Nei Xue Tang Museum
235 Cantonment Rd, Singapore 089766
www.neixuetang.org
Raffles Museum of Biodiversity Research (National University of Singapore)
Raffles Museum of Biodiversity Research
Department of Biological Sciences
Science Library Building (S6), Level 3
Science Drive 2
Fax: +65-6774-8101
rmbr.nus.edu.sg/visitor_info/index.html
28 Maxwell Rd, Singapore 069120
museum.red-dot.sg
The Republic of Singapore Navy Museum
112 Tanah Merah Coast Road
Outside Changi Naval Base (Next to SAF Yacht Club)
Telephone - +65 6544 5147
www.mindef.gov.sg/imindef/mindef_websites/atozlistings/navymuseum/home.html
Singapore Philatelic Museum (SPM)
23-B Coleman Street
www.spm.org.sg/SPMPortal
Singapore Coins and Notes Museum (SCNM)
www.singaporecoinsandnotesmuseum.com/the_news.php
Sports Museum
Sports Museum - YOG Gallery
Singapore Sports Council
1 Kay Siang Road #01-02
www.sportsmuseum.com.sg/index.html
The Intan
69 Joo Chiat Terrace, Singapore 427231
www.facebook.com/TheIntanSG
out and about in singapore
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The Regulation of Biological Product Marketing: An Introduction
A session from FDLI's Introduction to Biologics and Biosimilars Law and Regulation
Recorded March 31- April 1, 2020
Discuss the legal and regulatory requirements surrounding communications about biologics and biosimilars. Examine the definitions of misbranding, label and labeling, and off-label promotion. Explore the basic rules for advertising and promotion.
Jacqueline R. Berman, Partner, Morgan, Lewis & Bockius LLP
This session was recorded as part of FDLI’s Virtual Introduction to Biologics and Biosimilars Laws and Regulations Course in March/April 2020.
JACQUELINE R. BERMAN is a partner in Morgan Lewis’ FDA Practice. She counsels pharmaceutical and biologic companies, manufacturers, investigators, contract research organizations, and investors, as well as pharmacies, distributors, and healthcare institutions on US Food and Drug Administration (FDA), Drug Enforcement Administration (DEA), and US Department of Health and Human Services (HHS) regulatory, transactional, compliance, and enforcement matters. Ms. Berman advises clients on product development strategies, clinical and pre-clinical trials, expanded access, marketing applications, recalls, labeling, and promotion and advertising. She also works with companies on post-marketing obligations including adverse event reporting and compliance with current good manufacturing practices (cGMP). She is a frequent writer and lecturer on these issues. Ms. Berman is a graduate of American University, Summa Cum Laude, and The George Washington University Law School with Highest Honors.
+$100 for nonmembers
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Please use Chrome, Firefox, or Safari. If you are unable to use these browsers, please contact us at 202-371-1420 or [email protected] and we will assist you.
Virtual Learning FAQ
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On-demand webinar content is sent via email as soon as we are able to process and verify your order. This usually occurs within 1 business day.
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On-demand content can be played back on most devices.
If you have concerns, please click the Test Your System link to determine your device's compatibility, as well as system requirements.
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State of FDA Medical Product Manufacturer Inspections During and After COVID-19
Restarting Clinical Trials in the Wake of COVID-19
COVID-19 and Beyond: Development and Implementation of Recovery Action Plans for Medical Product Manufacturers
The Long-Awaited Biologics Transition Date Has Come: What Now?
daniel.zinn2020-05-19T10:26:06-04:00
Biologics License Applications (BLA): An Introduction
An Introduction to Violations, Enforcement, and International Issues in Biologics and Biosimilars
The Regulation of Biological Product Manufacturing: An Introduction
Post-Approval Pharmacovigilance of Biological Products: An Introduction
An Introduction to Biosimilar Product Regulation and Approval
Regenerative Medicine and Advanced Therapies: An Introduction
Regulation of Biological/Drug Development: An Introduction
Overview of Biological Products Law and FDA’s Regulatory Processes
The Regulation of Biologics and Biosimilars: An Introduction
Introduction to FDA Review and Approval of Biological Products
New, Emerging, and Continually Interesting Issues
FDA’s Recent COVID-19 Guidances Facilitating Expanded Access to Certain Medical Products
The CREATES Act Has Passed: What Does It Mean for the Generics Industry?
Reducing Anti-Kickback Risks Associated with Medical Products
Due Diligence: Ensuring Your Deal Doesn’t Collapse Due to Regulatory, Clinical, Quality, or Data Integrity Issues
Patient Assistance Programs: Recent Enforcement and Best Practices
From Approval to Coverage – FDA and CMS Jurisdictional Lines
Drug Pricing for the Food and Drug Community
Organic Chemistry for the Food and Drug Community
Real World Evidence: Data Requirements, Utilization, and Presentation
PDUFA and BsUFA Reauthorization: Key Changes Affecting Industry and Patients
Recent FDA Guidance Documents on Manufacturer Communications about Medical Products
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Karaoke Party Slot Review
Home » Games » Karaoke Party Slot Review
Microgaming has now officially chipped in on the Karaoke crowd with their slot Karaoke Party. It’s a simple game with not much sophisticated graphics about it and is extremely conventional in its presentation. Many may argue that’s like all Microgaming content. We wold argue, however, that is not the case, hence why we created this Karaoke Party guide.
So, if you’re into singing your heart out in front of a crowd of judgmental strangers whilst being a teeny bit drunk, this Karaoke Party slot guide for this Karaoke Party slot machine may just be the right thing for you. If, however, you don’t want to see this Karaoke Party review poke fun of your favourite Friday-night pastime, then we promise we’ll stop and give this Karaoke Party game the honest scrutiny it deserves and nothing less!
Gameplay And Return To Player (RTP)
Gameplay for the Karaoke Party slot game is incredibly simple and represents the standard slot formula with nine paylines altogether. The reel is a very normal 5×3 structure and players can select their coin amount using the slider at the bottom. There are special symbols to align in order to obtain a larger win.
In fact, the formula here seems to cut and dry that it looks almost as though Microgaming cut and pasted the design for this Karaoke Party game from another one of their slots, changed the colour and called it a day. While the symbols themselves aren’t shoddy, nor is the sound design and music, the look of the slot itself is very, very basic. At best, we would call it a good slot for beginners to go with, because of how uncomplicated it is.
The Karaoke Party slot RTP on the other hand makes up for this, we feel. Between 96% and 97%, it makes for a strong return on your money. However even this is fairly standard and unexciting. If the Karaoke Party RTP is anything to go by, it teaches us that some software developing companies are indecisive somethings. Why not one or the other? Why does it have to be in between?
In any case, as bottom line as the gameplay for Karaoke Party is, it isn’t terrible by any means. It’s just a little too basic for our taste. But, hey! If that’s your thing or you just want a simple, nice and easy video slot to get to grips with, Karaoke Party is your thing. There does need to be a point where players start and, like we said, this game is easily one of those titles where that could happen.
Extra Spins And Bonus Codes
If you’re still interested in this game despite what we have said in this Karaoke Party slot game review, we have a Karaoke Party bonus code for you to enjoy, so that you can have a fuller experience playing this game. The first Karaoke Party slot bonus code is for the lustrous Go Wild casino, where you can claim up to Karaoke Party slot extra spins to use to your heart’s content. Simply sign up to the site and make a deposit in order to claim them.
The second bonus code we have to offer is even more Karaoke Party extra spins. These can be taken up at Omni Slots where you can again just sign up and claim 20 extra extra spins to use on this particular slot game. And finally, sign up to Vegas Slots or BGO today and claim up to £400 in welcome bonuses to use on this game. This wouldn’t be a very good Karaoke Party game review if we didn’t get in at least three of the potential bonus codes in there somewhere. So, please! Enjoy. It’s on us.
Tips And Tricks – How To Play
When it comes to giving out tips on how to play a video slot, we usually dish them out to readers, because said slot has an unconventional or unusual element to which challenges the norm and may not be something the player is used to. Therefore, they will need a kind of guide in order to better understand the game and maximise the potential wins they could get out of it.
When it comes to Karaoke Party slot tips, however, that sort of thing seems almost redundant. In a sense, you have played Karaoke Party before – it’s like so many other slots out there it’s practically a clone. So, why would you need a guide on how to play Karaoke Party? Well, like we said, it’s a slot that would fit very well with beginners in the online gambling community. What kind of Karaoke Party slot review would we be if neglected new players?
Playing Karaoke Party is really simple. You have the spin button in the middle of several other buttons at the bottom of the reel. Click it to spin the reel once or you could select ‘Auto-Spin’ and it will do it for you. This will happen until you unselect it. You can select your coin value (however much you want to wager) by selecting the plus and minus arrows next the little numerical figure beside the spin button. As far as Karaoke Party tips go, there’s not much else to it than that. But at least we did our job and informed you on how to play Karaoke Party slot.
Overall, we’re not overly impressed with Karaoke Party. If you were looking for a more favourable Karaoke Party game review, then we’re sorry to disappoint. It’s a very basic game and that doesn’t do much for us. While it’s good for beginners, for veterans of the iGambling community, it’s same old, same old. That, by no means, is us saying it’s bad. Just slightly uninspired.
You can play it alright, but don’t expect many surprises. If that’s all you want from a video slot and this Karaoke Party slot game review has done little to change your mind, then great! You do you. Just don’t expect us to rave about it because, honestly, we don’t think it’s worth raving about.
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Furrylicious® Whitehouse Station, NJ - (908) 823-4468
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The Dandie Dinmont Terrier is characterized by his long, low body and “scimitar” tail, which looks like a curved sword, as well as his large soulful eyes and fluffy head of hair. Though small in stature, the Dandie has the character of a big dog, possessing confidence, intelligence, and independent nature. The breed's allowable coat colors are described as “pepper” and “mustard.”
The Dandie Dinmont was first recorded as a distinct breed around 1700 and has been popular with both gypsies and the wealthy at various points in his history. Originally bred to go to ground, he was well known for his skill in catching otter and badgers. Dandies were made famous when Sir Walter Scott wrote about them in Guy Mannering in 1814. Scott's farmer character was named Dandie Dinmont, after whom the breed was soon named.
As a companion, the Dandie Dinmont is affectionate towards his family, but it would not be uncharacteristic for a Dandie to show little interest in a stranger. The breed would do well in a rural or urban setting with daily walks. The Dandie does not shed, but his coat must be stripped about twice a year and brushed daily.
Terrier Group; AKC recognized in 1886.
Ranging in size from 8 to 10 inches tall at the shoulder and 18 to 24 pounds.
Vermin hunter.
Apartment is fine.
Fairly active indoors.
Daily moderate exercise.
Regular brushing.
Professional grooming recommended.
Little to no shedding.
Are you interested in purchasing a Dandie Dinmont Terrier?
PLEASE READ: These are beautiful, professionally bred puppies available for SALE.
They are NOT rescue dogs. These puppies are priced accordingly. If you are looking to ADOPT a homeless pet, please look for a reputable, local shelter or rescue.
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Whitehouse Station, NJ 08889
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AboutServicesProjectsArticlesLet's be fwends
To the List Archive
Gender defaults harm society, your phone is easily identifiable, and what comes after capitalism?
Get your update on what’s going on in the media and technology landscape every other week to your inbox.
Let's be Fwends is a journal about technology, experiences and the media landscape. And most importantly the role of all of us in all of that. It's about culture and it is about design. It's about marketing and it is about tech.
If you're interested in the bigger picture of digital design, this journal is for you.
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It's not as easy as you thought it would be.
LET'S BE FWENDS ISSUE #50:
GENDER DEFAULTS HARM SOCIETY, YOUR PHONE IS EASILY IDENTIFIABLE AND WHAT COMES AFTER CAPITALISM?
“A servant is the true reflection of his master.”
~ Arthur M. Jolly
Female voice assistants fuel damaging gender-stereotypes
Have you ever noticed that computers that talk typically have a female voice?
Alexa, Siri, Google Assistant are recent examples, but also car GPS systems typically have a female voice, as have auditory warning systems in airplanes (“Bitching Betty”, they call it)
In Science Fiction, there’s the female voice of “Her”. (There’s also the notable exception of HAL in 2001: A Space Odyssey)
The most common theory why this is the case is that females are considered less threatening, and the “service” role of an assistant is more in line with typical female gender-stereotypes.
The UN performed a study suggesting that the usage of female voices for digital assistants are encoding harmful gender-biases into technology and urges vendors to find ways to make digital assistants more neutral.
Your Smart Phone will betray you:
De-anonymising through sensors
Your smartphone contains a host of sensors, like a microphone, a camera, an accelerometer, or a GPS unit.
All of these sensors need to be carefully calibrated for optimal performance, which typically happens in the factory after assembly.
Four researchers where able to read out the fingerprint the sensor calibration of smartphones in less than one second by just using sensor output:
"A calibration fingerprinting attack infers the per- device factory calibration data from a device by careful analysis of the sensor output alone. Such an attack does not require direct access to any calibration parameters since these are often embedded inside the firmware of the device and are not directly accessible by application developers.”
A website could fingerprint, and therefore identify, your device in under second by just looking at sensor data and without your knowledge.
If the researcher’s claim is true and these fingerprints are more or less globally unique, there’s a huge security and privacy problem just around the corner.
What comes after Neoliberalism?
Adam Smith, the guy who started it all.
One thing you have to give to all the free-market proponents out there: They managed to blur the differences between neoliberalism as an ideology and capitalism as an economic system to such an extent that everybody thinks they are the same. Like, you can’t have capitalism without neoliberalism, which basically means insanely low taxes for the rich, a laissez-fair state, austerity and rampant privatisation.
Joseph Stiglitz says that it is clear by now that this ideology has failed, and asks: What comes next? And what should come next?
One point strikes me as especially important:
"The fourth key item on the progressive agenda is to sever the link between economic power and political influence. Economic power and political influence are mutually reinforcing and self-perpetuating, especially where, as in the US, wealthy individuals and corporations may spend without limit in elections."
It’s not just the US, it’s basically everywhere in the world. And with the shifts going on in the media landscape, as more and more money goes from traditional media to largely unregulated, uncontrolled, pseudo-neutral digital media platforms, this will be a key issue in the coming years.
Re-Designing something that maybe doesn’t need a redesign
What happens when you ask 50 designers to re-invent something everbody knows, has a very clear utility and has been built for thounds of years? Like, say, the chair?
Fun things. Fun things happen.
Design, Food, Makers in Linz
No idea what to do on 26.6. and 27.6.? Why not head over to Linz and attend some talks and workshops the good people at Creative Region are organising?
The workshop with Stiven Kerestegian - Head of Innovation at IKEA - sounds really interesting.
But honestly, I’d also like to ask him why their products are getting crappier and crappier all the time. This is not some tongue in cheek why-is-IKEA-furniture-so-hard-to-assemble (it isn’t), but a real and honest question about quality, sustainability and how long you’re supposed to own IKEA furniture. Because most of the stuff cannot be disassembled without seriously impacting stability or function, and thus not moved to a new place.
I’d really like to talk about that.
Check out the complete program, and enjoy some interesting talks and good food.
Always be careful about unintended consequences when designing something. As a not so unintended consequence please enjoy this virtual high-five. It's wednesday, and you've earned it. 📆
Enjoy what you see? Please recommend this newsletter to someone who might enjoy it equally. Thanks!
Send a tweet to your friends over at twitter.
View this issue of Let's be Fwends in your browser
Copyright © 2019 fwends, All rights reserved.
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CALL SUPPORT: +1 (780) 807-5502 support@g4usecurity.ca
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G4U SECURITY LTD.’s Privacy Policy does not apply to other advertisers or websites. Thus, we are advising you to consult the respective Privacy Policies of these third-party ad servers for more detailed information. It may include their practices and instructions about how to opt-out of certain options.
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Home Mobiles Realme X teasers surfaced on Flipkart ahead of July 15 launch
Realme X teasers surfaced on Flipkart ahead of July 15 launch
Flipkart has launched a teaser that confirms that Realme X will be available on its website.
By Komila Singh
Chinese technology brand Realme is all set to launch its Realme X smartphone in India on July 15. The company has also announced that it will be launching its limited-edition smartphone – Realme X Spider-Man: Far from Home Edition – in the country on the same day.
Prior to its launch, Flipkart has launched a teaser that confirms that Realme X will be available on its website. I the new teaser, Realme has posted #RealVoiceof India results on a dedicated page that says that 59 percent users prefer full-screen no-notch display, 66 percent users prefer super fast-charging battery, 62 percent users prefer a pop-up camera, and almost 81 percent users want a brilliant camera. Realme India’s CEO Madhav Sheth had tweeted a few weeks ago that Realme X will be launched in India with different specifications as compared to its variant that was announced in China.
While teasing the arrival of its Realme X smartphone in the country, the e-commerce website has confirmed that the device will be available for purchase when the handset will launch on July 15. Along with that, Realme X will also be available on the company’s official e-Store.
With the teaser, it can be concluded that the smartphone will sport a full-screen display, a pop-up camera and have support for fast charging.
Realme has not revealed the exact pricing of its Realme X smartphone, but the company has confirmed that its cost will be somewhere around Rs 18,000.
Realme X specifications and details:
Realme X runs ColorOS 6.0 based on Android Pie and features a 6.53-inch full-HD+ (1080×2340 pixels) AMOLED display that has an aspect ratio of 19.5:9 aspect ratio. It also comes with Gorilla Glass 5 for protection. The smartphone is powered by an octa-core Snapdragon 710 SoC, paired with up to 8GB of RAM and 128GB of internal storage.
On the imaging front, the Realme X comes with a dual rear camera setup that comprises of a 4MP primary sensor with an f/1.7 lens and a 5-megapixel secondary sensor with an f/2.4 aperture. There is also a 16-megapixel selfie camera on the front that has an f/2.0 lens and is housed in a pop-up selfie camera.
Apart from that, the device houses a 3,765mAh battery that supports VOOC 3.0 fast charging technology. The connectivity options of the handset include 4G LTE, Wi-Fi 802.11ac, Bluetooth v5.0, GPS/ A-GPS, USB Type-C port, and Dolby Atmos audio.
Komila Singhhttps://www.gadgetbridge.com
Komila is a one of the most spirited tech writers at Gadget Bridge. Always up for a new challenge, she is an expert at dissecting technology and getting to its core. She loves to tinker with new mobile phones, tablets and headphones.
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Construction Injury
Vehicle Property Damage
Cybercrime Insurance Claims
1218 3rd Ave Ste 1000
Map Us >
GET TO KNOW GALILEO LAW
PHILOSOPHY AND VALUES
Any law practice can make promises about service and results, but trust our clients. Their testimonials are your best resource to learn why you will have a better experience with our practice than with any other diminished value attorney in Seattle.
Seattle personal injury attorney and diminished value lawyer Paul Veillon has represented severely injured persons since 2004 in claims against insurers, major corporations, and government agencies. In and out of Court, through jury trials, and before the Supreme Court of this state, he has prevailed and counseled clients and small businesses in financial crisis, fought for the rights of the accused and victims of discrimination, and helped ordinary people who needed justice.
Attorney Paul Veillon has earned the highest 10/10 rating and the Client’s Choice Award on Avvo.com. He is an Eagle member of the Washington State Association for Justice (WSAJ), published several peer-reviewed articles on insurance and injury claims, served on the Trial News Editorial Board, co-chaired Continuing Legal Education seminars, associated with other firms that required his special expertise in an aspect of their client’s claims or jury trial expertise, and serves as the 2015 Vice-chair of the WSAJ Insurance Law Section and as a member of the WSAJ CLE Committee.
WHY WE’RE UNIQUE
WE ONLY SUCCEED WHEN YOU SUCCEED
We fight for the justice you deserve. You pay nothing for our time and expertise until we win your case.
OUR CLIENTS RECOGNIZE OUR SUPERB SERVICE
We know our commitment to service is working. Our clients have told us so.
WE HELP YOU WITH ALL ASPECTS OF YOUR CLAIM
We help you with all aspects of your claim, from collision repair to finding the best medical resources available to restoring balance to your quality of life
BOUTIQUE FIRM SERVICE WITH MAJOR FIRM POWER
Insurance companies are powerful adversaries. We are powerful advocates capable of handling substantial and complex cases. Yet you will always know that your attorney is there to help you.
PROVEN TRACK RECORD OF SUCCESS
From out-of-Court negotiations to jury trials to the Supreme Court of Washington, for over a decade attorney Paul Veillon has prevailed in catastrophic injury and diminished value claims against major insurers, construction contractors, and government agencies.
PREMIER DIMINISHED VALUE ATTORNEY
Paul Veillon is the leading Ferrari, Lamborghini, Porsche, and “daily driver” diminished value attorney in Seattle, Tacoma, Bellevue, Redmond, and throughout Puget Sound.
Paul Veillon
Mr. Veillon has lived in the Puget Sound area his entire life. After graduating valedictorian from Oak Harbor High School, he earned a Bachelor of Science Degree with Honors in Physics from the University of Puget Sound. Then he went to law school at night so he could work full-time to support his family, graduating Magna Cum Laude from Seattle University in 2003.
He and his wife have four children and live in Seattle. He has an intense passion for golf and chess, though he's no expert at either. He also enjoys spending time with his family, especially on Orcas Island or at Gasworks Park.
Anna Allard
Paralegal Case Manager
Anna has almost a decade of experience serving injured clients.
Like Paul, she has close personal experience with the impact of catastrophic injuries. A collision rendered her cousin quadriplegic as a teenager; she cared full-time for a quadriplegic collision victim for over a year before beginning her legal career. She has a deep passion for holding careless people and corporations accountable for such life-altering events.
Anna maintains an exceptional rapport with Galileo Law’s clients. Her empathy and calming presence supports clients at depositions, mediations, and trials while Mr. Veillon fights for their rights.
Kamber d'Ombrain
Kamber is a truly exceptional human being.
She is a single mother who put herself through school to become a pharmacy technician before beginning a long career at Rite Aid. The insurance billing skills she learned there serve Galileo Law clients on a daily basis. She had followed Anna to care for the same quadriplegic collision victim and proved her diligence, attention to detail, and tenacity there while gaining a true understanding of the impact of horrible collision injuries.
Kamber has been close friends with Paul and Anna since the 20th Century. When Galileo Law sought a legal assistant, we did not even need to advertise for the position. Kamber was the obvious choice, and Galileo Law is blessed to have her.
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GTA Online Valentine's update brings back mobster chic
By Connor Sheridan 10 February 2016
"Be still, my beating heart," is what you'll say when you're fighting the recoil on your new Gusenberg Sweeper in GTA Online. Rockstar Games released the second-ever Valentine's Day update for GTA 5's multiplayer counterpart today after skipping the romantic festivities in 2015, and once again it's only for current-gen consoles.
Not only will classics-loving criminals get a second chance to buy the Tommy Gun-inspired Gusenberg, "Be My Valentine" introduces the new-and-improved Albany Roosevelt Valor. The buggy (complete with siderails for suicidal hop-ons) has a full suite of tweaks available at Los Santos Customs. The original Roosevelt is also available for historical preservation purposes.
Another aspect of the Be My Valentine update is the new "couples-based" adversary mode, Till Death Do Us Part. The video teaser from Rockstar looks like a Bonnie and Clyde inspired chase - with two well-armed players pursued by a much larger team - but we won't know for sure until it goes live on Friday.
While you're waiting, you can pick up all the clothes which were previously available in 2014's "The Valentine's Day Massacre Special" on top of a new selection of stockings, boxer shorts, bustiers, and other impractical crime accoutrements. I'm not sure when the special Valentine's gear will go back into the Rockstar Vault, but you should probably get your shopping done by the end of the weekend.
Seen something newsworthy? Tell us!
Connor Sheridan
Connor has been doing news and feature things for GamesRadar+ since 2012, which is suddenly a long time ago. How on earth did that happen?
Hitman 3 review: "a slick and entertaining conclusion to the trilogy"
Best gaming chair for PS5, PS4, and Xbox: get comfy whatever your console setup
Best card games - find new favorites that won't get lost in the shuffle
The best Xbox One steering wheels and their cheapest prices
GamesRadar+ is part of Future plc, an international media group and leading digital publisher. Visit our corporate site.
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Home Food The Buzz of Honey!
The Buzz of Honey!
Lisa Doss Food Gardening Home In the Kitchen 01 Jul 2019 Comments Off
What could be more eye-opening than learning that 75% of all store-bought honey contains artificial sweeteners, such as rice, wheat, and sugar-beet syrups? Despite the high-dollar price, the missing ingredient is pollen! By removing the essential microscopic particles, manufacturers can not only conceal the identity of the source of the honey but pass government purity tests. New technology, termed “Nuclear Magnetic Resonance” (NMR), can determine the quality by recognizing syrups that come from plants. Surprisingly the United States does not have a standard for identifying purity. In 2011, a lab analysis through an American university discovered that honey from big box stores, drugstores, fast-food chains and elsewhere contained dangerous antibiotics, artificial sweeteners, and large quantities of metals in their brands.
Considering the production of seven million pounds of honey produced annually, how do you know which brands are worth the price?
The Do’s and Don’ts of Buying Honey
Do not trust a label which states, “100% Honey” or “U.S. Grade A.”
Be wary of labels that list multiple countries of origin, and include the United States.
Look for raw and especially locally made honey at small markets, some specialty food stores, and farmer’s markets.
Contact your local beekeeper’s association. The Forsyth County website, fcba.wildapricot.org/, includes a tab titled, “Local Honey for Sale.”
Ask family and friends where they purchase their “raw” honey. Buying from a reputable source is critical. The extraction and canning process begins in late June; ask to have your name added to a “wait” list. The wait may be long, but worth it!
Amazing Facts about the Honeybee
Did you know one honeybee can produce one tablespoon of honey in its lifetime? Please do not swat the honeybee, it is either on a foraging mission to gather nectar, possessing a high water content of between 60% and 80%, or returning to the hive. Through the transformation process to honey, the bees will flap their wings to remove the moisture. Statistics state that it takes approximately 680 honeybees to fly 32,500 miles to collect nectar from over a million flowers. Once capped, the honey will fill roughly one nine-ounce jar.
Additionally, if you have ever wondered about the shape of the honeycomb, a hexagon offers the most efficient pattern to ensure the cells do not waste space. Despite its delicate structure, the comb holds a tremendous amount of weight.
What is Raw Honey?
To achieve perfection, honey does not require pasteurization to remove the nutrients—such as vitamins and antibacterial and antioxidant properties—which keep the body’s immune system healthy. In place of this type of production, there is a more straightforward process. When beekeepers remove frames directly from the hive, the frames go through a procedure of extraction using centrifugal force. After straining it to remove wax and other particles, the honey is in its perfect state and ready for canning.
Only raw honey contains 20 vitamins, 18 amino acids, 16 minerals, and antibacterial, antiviral, and antifungal properties. Addition to B2-B6, and C vitamins, ingredients include magnesium, potassium, calcium, sodium chlorine, sulfur, and phosphate. And, it remains eternally preserved!
Save the Bees, Save the Flowers
The message to save the bees also extends to flowers, fruit trees, vegetable gardens, and weeds such as the dandelion. What caused the world-wide plea for protection? Pesticides and chemical-resistant crops placed our pollinator populations in peril; yet, that is just one factor. Farmers, who converted wetlands and prairies to 35,000 square miles of crops, have altered pollinating habitats. Each of us can play a part in our yards by planting native species that will attract the birds, variations of bee species, butterflies, and other pollinators. Additionally, start reading labels on the chemicals you use to ensure safety for pets and all winged creatures!
In our love for raw honey, we must advocate an environmental kindness towards pollinating creatures while supporting our local beekeeping communities. Find a beekeeper, today!
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Lisa Doss
Forsyth Magazines writer since 2012. Lisa is originally from Maryland and, after living in New York, Colorado and Texas, she’s proud to finally call North Carolina home. Lisa shares a home with her husband of 10 years, Kevin. Together, they have daughter, Sayre and their angel-son, Finn who lived two years. Their family also includes two dogs. Lisa has a degree in education and, as such, writes many educational articles for the magazines. Lisa enjoys traveling, is an avid reader and gardener and has done extensive work on her family’s genealogy. When it comes to writing for Forsyth Magazines, Lisa said, “I love writing spring themes in winter, back to school articles in the heat of summer, and, best of all, starting to anticipate the Christmas season in October.”
View all posts by Lisa Doss
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Clean Green
“What If” Presents the First Steps of Food Storage
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Eddie Kingston Recalls 'F*ck It' Moment Before Cody Rhodes Match
Eddie Kingston made his AEW debut on the July 22 episode of Dynamite, answering the TNT Title open challenge of Cody Rhodes.
Kingston made an immediate impression with his promo against Cody followed by a No DQ match.
Related Article IMPACT Wrestling Results & Live Coverage for 1/19/21 Hard to Kill Fallout, Rhino vs Eric Young
Speaking to Renee Paquette on Oral Session, Kingston recalled things clicking for him moments before he walked in front of the camera.
"Cody was the pressure moment," said Kingston. "Right before I went out, that's when I said, 'Fuck it.' The guy at Gorilla, who knows that I never want pyro," he said, 'Go' and I went, 'Fuck it' and started talking. They had to stop me because I called him Cody Rhodes like three times. I was all the way in Eddie Kingston mode, which is 'fuck the world, everyone is against me.' When Tony Khan walks out and is like, 'Aright, cut.' I'm like, 'What the fuck do you want? Oh wait. Hey. Hey Tony. What's up? What do I have to do?' I told [Cody], 'I'm going to put pressure on you and hit you, but you'll be able to go home to your wife.'"
Kingston lost the match to Cody, but earned himself a contract.
Elsewhere during the podcast, Kingston discussed his post-event speech at the Brodie Lee tribute show. You can find his full comments by clicking here.
Kingston is set to face PAC on Wednesday's Dynamite. Fightful will have full coverage of Dynamite beginning at 8 p.m. ET.
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Home » News & Guides » UK currency moves higher on future hopes
UK currency moves higher on future hopes
After a period of difficulty for the UK currency, sterling has today continued its recent rise against the euro and the dollar amid claims that the UK recession is coming to an end. While these claims have yet to be rubberstamped by a number of economic forecasters, there is no doubt that under the surface there is an increase in confidence and potential activity. Whether this is enough to suggest the UK recession is over and the economy has turned a corner is still very much open to debate. However, this has not stopped investors from piling into sterling on hopes for the future.
While the UK currency is on the up, the euro and the dollar are both suffering from concerns that their relative economies are going to struggle in the short to medium term. The euro in particular has had significant problems of late amid concerns that issues with some of the smaller European member states could spread over the next few weeks and months. The US on the other hand has seen a mixed performance by its economy over the last few weeks with great hope taken from the decision to accept repayments from "bail out banks" although concern that the economy has not quite performed as people had expected.
European economies under severe pressure
As the ongoing expansion of the EU continues at great pace many people believe that this rate of growth in member numbers needs to be reined in. Figures suggest that some of the more recent additions to the EU are struggling more than the average economy in Europe which is placing more and more pressure on EU budgets and the European Central bank. We have seen a significant fall in many of the eas... Read More
Are we all to blame for the UK recession?
As financial websites and the financial press continue to rain down criticism on the UK government and UK financial institutions, it is fair to pin all of the blame on these third parties? Have we not all played a part in the rise and fall of the UK economy? Can we really put our hands on our hearts and say we did not overextend our finances?
They will be very few people in the UK w... Read More
Will the UK economy really bounced back stronger?
Gordon Brown's suggestion that the UK economy will bounce back stronger than ever before has given some people hope in the UK but many are waiting for the proof behind the very upbeat forecast. The figures would suggest that the UK is currently weaker than it has been at any time in modern history and taxpayers and consumers are more concerned than ever before about the immediate outlook.
<... Read More
John Lewis announces record Christmas sales
As we approach the latter end of the festive retail period high street giant John Lewis has today announced record takings of £102.4 million for the week to December 5. This is almost £1 million higher than the previous record set in 2007 although when you consider this performance against the economic backdrop at the moment it is even more impressive. While takings have increased significant... Read More
Is the Gordon Brown bounce over?
As bizarre as it may sound, the economic turmoil within the UK had appeared to be the best option for Gordon Brown to win the next general election. Since the slowdown began his rating with voters in the UK has increased substantially but recent signs suggest that the Gordon Brown "bounce" could well be coming to an end. A number of recent polls have shown support for the Conservative Party is inc... Read More
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The First Federation Trust, Blackpool CE Primary School, Liverton, Newton Abbot, TQ12 6JB
The First Federation Trust Board of Directors
There is one board of directors which is the governing body for all the schools within the First Federation Trust.
The board of directors has three core functions:
Holding the Chief Executive Officer (CEO) to account for the educational performance of the Trust schools and their pupils, and the performance management of its staff; and
Overseeing the financial performance of the schools and making sure the Trust money is well spent.
The board of directors recognises that the CEO is responsible for the implementation of policy, day-to-day management of the Trust schools and the implementation of the curriculum.
The board of directors meets four times a year: in September to elect the Chair and agree principles of delegation, and then at the end of each term.
There are up to eleven positions on the board: the CEO, six foundation directors, and up to four co-opted directors. Directors are appointed as follows:
Foundation directors: five positions appointed by EDEN (Exeter Diocesan Network of Education) and one position appointed by Salisbury DBE (Diocesan Board of Education). EDEN and Salisbury DBE are both Foundation Members of the First Federation Trust.
Co-opted directors: appointed by the directors
There are parent hub council members from each school on each hub board.
There are currently three main committees of the board of directors with delegated power: the Education committee, the Strategic & Finance Committee and the Audit Committee.
The Education committee meets half termly and focus on school improvement, curriculum and inclusion. Its remit is:
To regularly review the success of the Trust strategic plan and the schools school improvement plans with a particular focus on outcomes for vulnerable children, and to plan for the year ahead.
To monitor the progress and impact of the Maths, English, Pupil Premium and Assessments projects.
To review the leadership and governance structures of the Trust to ensure they are still fit for purpose and make recommendations for appropriate changes to the board of directors
To consider recommendations made by the hub / transition boards and act on the key points raised by them.
To review the yearly cycle of decision making for recommendation to the board of directors.
To ensure that the Trust educational/child-related policies comply with statutory requirements
To ensure that the necessary structure is in place to implement safeguarding policies and procedures, and to monitor their effectiveness.
The Strategic & Finance committee meets half termly and focus on strategic planning and resources. Its remit is:
To plan for the year ahead, ensuring resources are used and targeted appropriately.
To review the leadership and governance structures of the Trust to ensure they are still fit for purpose and make recommendations for appropriate changes to the board of directors, in particular to ensure directors have the right standards to achieve a good level of financial health and resources management, in the line with the ESFA school resource management self-assessment tool.
To act on requests from schools interested in joining the Trust, ensure due diligence is conducted and make recommendations to the board of directors as to the expected impact on the Trust in accordance with the agreed growth policy.
To establish and review a governance code of conduct.
To ensure that Trust non educational/non child related policies comply with statutory requirements.
To monitor Finance, Personnel and Health & Safety matters and ensure they fit with the strategic plan for the First Federation Trust and that resources are deployed efficiently
To establish and review a code of conduct for the board of directors
To act ensure value for money
To offer additional support to the Chief Executive Officer on difficult and sensitive issues
The Audit committee meets termly and focus on internal scrutiny and risk management. Its remit is:
To act as the Audit Committee for the trust, as defined by the Academies Financial Handbook
To liaise with external and internal auditors, in particular to agree an appropriate programme of internal scrutiny and ensure recommendations from audit reports are implemented.
To ensure information that affects funding submitted by the Trust to the DfE and ESFA is accurate and in compliance with the funding criteria
To report to the board of directors on significant audit matters.
There are three other committees of the board of directors with delegated powers – the Admissions Committee, the Pupil/Staff Discipline Committee and the Appeals Committee – which meet as needed.
Hub boards have delegated responsibilities but no delegated powers. Their remit is as follows:
Educational performance:
To support and challenge senior education leaders for the educational performance of the hub schools and the progress made against the school specific improvement priorities;
To monitor and evaluate the agreed intent, implementation and impact of the schools' curriculum, and to consider evidence about how effectively the curriculum is achieving its aims for pupils;
To review detailed pupils’ progress and attainment data for the schools, and how they compare with national and Trust targets and with local, regional and national averages, for the whole schools and for specific sub-groups of pupils (e.g. Pupil Premium Children and SEN children);
To assess the impact of the Trust internal consistencies/non negotiables on school improvement, including the quality of teaching, pupils’ academic and personal development, pupils’ behaviour, pupils’ attendance and pupils' welfare (including safeguarding arrangements).
Ethos and and links with parents and the community:
To review parental and community engagement;
Where appropriate, to monitor how Church schools are maintaining and developing their Christian distinctiveness;
To monitor formal parent complaints.
Risk management:
To monitor the risk register for the hub, identify any significant changes / additional to be made to the risk registers and how/whether these can be mitigated.
To report on the above to the Education and/or Audit committee, highlighting key issues, risks and successes, and making recommendations where appropriate.
Local Governance Committees
These are for schools that wish to retain a local governance body and/or which the board believes would benefit from having a local governance body. They have delegated responsibilities but no delegated powers. Their role is to assess the impact of the school's membership of the Trust on pupils' academic & personal development and behaviour, the curriculum and the quality of teaching & learning, and to engage with local stakeholders and provide a link from the local community. They report to the hub board, highlighting any issues and making recommendations where appropriate.
Advisory groups are used to inform and support the work of the board. They are not committees of the board of directors.
Ethos and Community groups: one for each Trust school, composed of children, staff and members of the community, supported by the foundation directors, who help support the ethos of each school and the Christian distinctiveness of our Church schools
Parent Council: one for the Trust, composed from at least one parent elected from each Trust school.
The document below summarises the governance structure of the Trust and incorporate the scheme of delegation agreed by the board during their first meeting of the year.
Governance scheme of delegation 2020-21
Please note that during the period of schools' closure and partial opening during 2019-20, the board varied the scheme of delegation in order to be able to take the rapid decisions needed to respond to the situation across the Trust. Delegation to the education, strategic & finance, and audit committees, and to the hub boards, was suspended during this period, as agreed in the resolution below. The board met more frequently than planned in order to fulfill its responsibilities.
Resolution 1 - Scheme of delegation variation.pdf
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Join our trust - Please call 01626 821316 or email admin@firstfederation.org.uk
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You are browsing: All The Complete Book of 1910s Broadway Musicals
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The Complete Book of 1910s Broadway Musicals (Hardback)
Dan Dietz
Pre-order for despatch on publication.
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Film, TV & Drama TheatreMusic & Dance Music Books Music: styles & genres MusicalsReference & Research Encyclopaedias & reference works Reference works Publisher: Rowman & Littlefield Publication Date: 15/06/2021 ISBN-13: 9781538150276 Details: Type: Hardback Format: Books
Availability: Pre-order for despatch on publication. Pre-Order
Dan Dietz was a Woodrow Wilson Fellow at the University of Virginia and taught courses in composition, world literature, and the history of modern drama at Western Carolina University. Dietz later served with the U.S. Government Accountability Office and the U.S. Education Department. He is the author of Off-Broadway Musicals, 1910-2007: Casts, Credits, Songs, Critical Reception and Performance Data of More Than 1,800 Shows, which was selected as an outstanding reference source by the American Library Association. He is also the author of The Complete Book of 1920s Broadway Musicals, The Complete Book of 1930s Broadway Musicals, The Complete Book of 1940s Broadway Musicals, The Complete Book of 1950s Broadway Musicals, The Complete Book of 1960s Broadway Musicals, The Complete Book of 1970s Broadway Musicals, The Complete Book of 1980s Broadway Musicals , The Complete Book of 1990s Broadway Musicals, and The Complete Book of 2000s Broadway Musicals, all published by Rowman & Littlefield.
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Be Drag Fabulous: How to Live Your...
(Hardback)
Katie Mockridge; Katie Mockridge
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Doing the Time Warp: Queer...
Sarah Taylor Ellis
A Teacher's Guide to Musical Theatre
Kenneth Pickering; David Henson
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How Kellogg worked with ‘independent experts’ to tout cereal
AP Food Industry Writer
NEW YORK — On its website, Kellogg touted a “Breakfast Council” of “independent experts” who helped guide the company’s nutritional efforts.
Nowhere did it say this: The maker of Froot Loops paid the council members and fed them talking points, according to a copy of a contract and e-mails obtained by the Associated Press.
The company paid the experts an average of $13,000 a year, prohibited them from offering media services for products “competitive or negative to cereal” and required them to engage in “nutrition influencer outreach” on social media or with colleagues.
►Related: Kellogg Co. urges Trump to uphold Paris Agreement
“I’m still feeling great from my bowl of cereal & milk this morning! Mini-Wheats are my fave,” a dietitian on the council posted during a Twitter chat with Kellogg. Another council member and dietitian chimed in to say they were her favorite, too, and included a photo of the cereal.
►Related: Kellogg reveals new cereal: Cinnamon Frosted Flakes
For Kellogg, the council — in existence between 2011 and this year — deftly blurred the lines between cereal promotion and impartial nutrition guidance. The company used the council to teach a continuing education class for dietitians, publish an academic paper on breakfast and try to influence the government’s dietary guidelines.
Kellogg said the council’s activities were clearly sponsored.
Yoni Freedhoff, an obesity expert at the University of Ottawa who writes about industry influence in nutrition, said he didn’t believe it was clear to the public that the council members were compensated, especially since Kellogg described them as “independent.”
“It’s not an automatic leap. I don’t think people think about these conflicts that deeply,” he said.
Dayle Hayes, a dietitian who participated in the Twitter chat in 2014, said in an email that she prides herself on her ethics and transparency and that her disclosure practices have changed as standards have evolved. Based on current standards, she said she would include the word “ad” in tweets referencing Kellogg products. She said she did not share any information without appropriate disclosures.
Kellogg Co. said the experts disclosed their affiliation with the company in public engagements. Still, the company said it could see how its use of “independent” could create confusion. It said later it decided not to continue the council, and the website page is no longer online.
'Are those regular Fritos?'
Kellogg said on its website that the breakfast council helped guide the company. But it wasn’t always clear who was providing the guidance.
When Kellogg sent the council research it commissioned, Hayes expressed enthusiasm and requested language to share the information. Hayes and Sylvia Klinger, another dietitian on the council, tweeted the lines Kellogg provided verbatim. Hayes included the word “advisor” and Klinger included the word “client.”
Kellogg also supplied the experts with a “toolkit” of tweets for a promotional event in New York. When the council members received a critical email from someone they didn’t know criticizing their work with the company, the company suggested a response for that, too.
“I appreciate and share you(r) interest in the health of our children,” the suggestion read. “It’s for this very reason that I work with Kellogg.” The council members decided not to respond.
The work with dietitians wasn’t unusual. Coca-Cola has paid dietitians who wrote columns casually suggesting mini-sodas as a snack. Disclosures said the author is a “consultant” for food and beverage companies, “including Coca-Cola.”
Jessica Levinson, a dietitian who has appeared in TV news segments for Coke and PepsiCo’s Frito-Lay, told the AP producers were told if her healthy eating tips were sponsored. Yet the disclosures weren’t always shared with viewers.
In a segment on NBC Baltimore on “dos and don’ts” in 2009, Levinson presented bags of Fritos with dip — as an example of a “do.”
“Are those regular Fritos?” asked the reporter, indicating her surprise.
'Key messages'
One of the breakfast council’s accomplishments was publishing an academic paper defining a “quality breakfast,” which Kellogg touted as being written by “our independent nutrition experts.”
A Kellogg employee oversaw the editing and provided feedback, including asking for the removal of a line saying a recommendation that added sugar be limited to 25% of calories might be “too high.”
Kellogg said the paper was a supplement and that its involvement should have been clear. It noted a disclosure said a draft was written by an agency that represents Kellogg.
The Journal of the Academy of Nutrition and Dietetics said editorial rules for supplements are the same as for regular articles. The paper underwent peer review, and an editor suggested reducing or eliminating the detailed discussion of cereal, especially since the sponsor was a cereal company.
To amplify the paper, Kellogg planned to reference it in comments submitted for the government’s dietary guidelines, emails obtained by the AP through a public records request show. Kellogg also sent its breakfast council a plan with “Key Messages” to promote the paper.
One message: “A variety of Kellogg’s products and tools make it easier to enjoy a quality breakfast.”
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Bal de Gala Allemand 2012
German Montréal
Home » The Society
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Are you interested in becoming a member of the German Society? We are always looking for new members committed to furthering our objectives and interested in getting involved.
You can mail or email us the PDF application form.
By joining us, you are playing an important role in representing and promoting the German culture, heritage and language in Montreal. Additionally, you have the chance to be part of one of the oldest charitable organizations in Montreal and Canada.
As a member you have the opportunity to participate in our charitable and cultural activities, and help organize these by involved on our committees and working groups. Furthermore, the Society regularly organizes activities for its members, including for example public lectures on current topics, museums tours, etc.
Individual Membership $ 40.00 CAD
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Individual membership is open to any individual wishing to further the purposes of the Society (see by-laws). There is no minimum age for membership; however, minors under the age of 18 are not eligible to vote at the Annual Members’ Meeting.
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‹ By-Laws of the German Society, 1992 up Fundraising - Christmas Campaign ›
Recent News and Updates
Fröhliche Festtage – Joyeuses Fêtes – Happy Holidays!
Gutes tun und Glück gedreht
It is time: Invitation to our Christmas raffle with virtual wheel of fortune
Christmas charity campaign: it's worth it!
Aktuelle Informationen: Einreise und Quarantäne in Deutschland
Die virale Stadt - Statu Quo
Virtual German Montreal Stammtisch
J. S. Bach Concertos feat. Pacific Baroque Orchestra
Sat, 30/01/2021 - 10:30 to 11:30
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The Relief and Welfare Fund of the German Society of Montreal is a charitable organization registered with the Canada Revenue Agency (BN 119115061RR0001).
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Home Device Specifications
Tecno Camon i2 Specifications, Price, and Review
Updated on January 3, 2020 by GDT Staff
Tecno Camon i2 was announced in september 2018 which sports a 6.2-inch IPS LCD display with a screen resolution of 720 x 1520 pixels.
Tecno Camon i2 is powered by a ARM Cortex-A53, 2000 MHz, Cores: 4 with MediaTek Helio A22 (MT6761) chipset coupled with 3GB of RAM and 32GB of internal storage. It also supports an external memory card. The device came out of the box with Android 8.1 Oreo under HiOS 4.1 and backed by a 3750 mAh battery (Non-removable).
As far as the camera concerned, the device has a dual-camera setup with 13MP + 2MP primary sensors and a selfie camera with an 16MP lens. Other connectivity option includes 4G-VoLTE, GPS, Glonass, Bluetooth, Mobile Hotspot, accelerometer, light sensor, proximity sensor, and compass. etc. The Tecno Camon i2 come with a face unlock feature.
[device id=”1335″]
Tagged With: Tecno, Tecno Camon i2
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GK & Current Affairs: October 21, 22, 2014
1. Who among the following is a golf player?
[A]Anirban Lahiri
[B]Pankaj Advani
[C]Geet Sethi
[D]Hetul Shah
Golfer Anirban Lahiri has recently won the Venetian Macau Open championship. He notched up his second title of the year, with a sparkling final round of five-under 66. In this question, Pankaj Advani and Geet Sethi are snooker players while Hetul Shah is a Chess player.
2. Recently, which among the following actors have won the Global Diversity Award 2014?
[A]Amitabh Bachchan
[B]Shahrukh Khan
[C]Aamir Khan
[D]Salman Khan
Bollywood superstar Shah Rukh Khan was presented with the Global Diversity Award 2014 for his outstanding achievements in the field of cinema and his contributions in philanthropic endeavours.
3. Who has been appointed as the new head of Kalakshetra Foundation by the Union Government Ministry of Culture?
[A]N.Gopalaswami
[B]Priyadarsini Govind
[C]Karunaker K Menon
[D]S.Rajagopalan
N.Gopalaswami
The government has appointed former Chief Election Commissioner N Gopalaswami as the new chairman of the governing board of the Chennai-based Kalakshetra Foundation.
4. With reference to the recently launched first ever National Mental Health Policy, which among the following is / are correct statements?
1. To provide access to universal psychiatric care
2. It was adopted under Resolution WHA 65.4adopted at the 65th World Health Assembly held in Geneva in 2012
3. Indian government spends 0.06% of its health budget on mental health, according to the World Health Organization’s Mental Health Atlas of 2011
Select the correct option from the codes given below
[A]Only 1 & 2
[B]Only 1 & 3
[C]Only 2 & 3
[D]1, 2 & 3
All three provisions are true about the new National Mental Health Policy.
5. The Sansad Adarsh Gram Yojana was launched on the birth anniversary of __?
[A]Mahatma Gandhi
[B]Sardar Vallabhbhai Patel
[C]Jai Prakash Narayan
[D]Shaheed Bhagat Singh
Jai Prakash Narayan
PM Narendra Modi launched Saansad Adarsh Gram Yojana (SAGY) on the birth anniversary of Lok Nayak Jai Prakash Narayan.
6. Which among the following will be the nodal officer for implementing the Sansad Adarsh Gram Yojana?
[A]Member Parliament
[B]Prime Minister
[C]District Collector
[D]Sarpanch
District Collector
The scheme will be implemented by a village development plan that would be prepared for every identified gram panchayat. The MPLADS, would be available to fill critical financing gaps. The planning process in each village will be a participatory exercise coordinated by the nodal officer, the District Collector. The MP will play an active facilitating role in this exercise.
7. Which among the following is / are correct statements with respect to the IRNSS-1C?
1. It was launched by a Polar Satellite Launch Vehicle
2. It carried a payload namely a C-band transponders to help in laser ranging. (to help Military / artillery range estimation)
3. It was the launched from Satish Dhawan Space Centre in Sriharikota
Select the correct option from the codes given below:
All three provisions are correct about the launch of IRNSS-1C, which is the third navigation satellite.
8. Which among the following countries does not have a fully functional global navigation system?
[A]USA
[B]Russia
[C]Germany
[D]China
Only 3 countries have USA,Russia and China. USA has GPS, Russia has GLONASS and China has Beidou as the navigation systems.
9. A Nobel Prize in each category can be shared among maximum?
[A]2 persons
[B]3 persons
[C]4 persons
[D]5 persons
A maximum of 3 persons can be awarded a Nobel Prize in each category. Each of the nominated persons should be alive.
10. What is the ranking of India in the recently released Global Hunger Index?
[A]63
[B]89
[C]76
[D]55
India’s position in the GHI 2014 is 55 out of 76 nations. Last year India was at 63rd position. Even though its position has improved but it is still far behind countries like Thailand, China, Ghana, Iraq, Sri Lanka, Nepal, Bangladesh and Pakistan.
The above 5 questions are part of Daily Current Affairs 20 MCQs Series in GKToday's Academy Android Appplication. This series can be subscribed in the app only for Rs. 750/- for entire year. Download Now
Category: Daily Current Affairs -2020: Objective [MCQ] Current Affairs Quiz
Tags: Current Affairs Quiz - November, 2014
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srinu pothala
good job sir
K. Sai Kumar
this was a nice GK , I like it So much , Thanks….
VIKAS S PAWAR
Good explained.
anshul
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Where Do We Go After J.Crew?
The brand that drafted legions of men into fashion has filed for bankruptcy. Where do they shop now?
By Gerald Ortiz
J.Crew recently filed for Chapter 11 bankruptcy, leaving many fans wondering where they should shop now.
Filing for bankruptcy sounds like a death knell for any brand, but that's simply not the case. There are several ways to go about bankruptcy and the two main ways are liquidation and restructuring. Essentially, if a brand wants to stay in business, they go through restructuring to manage its debts, restructure the company and continue in the hopes of getting out of the hole. But if a brand wants to throw in the towel — liquidation. That's when you get going-out-of-business sales.
The brand started actually started in 1947 and was known as Popular Merchandise, Inc. and sold women's clothes through its store, Popular Club Plan. In the 1980s, it saw huge growth in its catalog business, selling millions of dollars worth of clothes in the vain of Ralph Lauren with a smaller price tag.
The brand continued its success and jumped from the page to brick and mortar in 1989 in downtown Manhattan. Since then, J.Crew has opened hundreds of stores across the U.S., and became the go-to destination for men's style in the late 2000s through the mid-2010s, thanks to Frank Muytjens and Todd Snyder, among others.
The modern-day prep aesthetic was mixed with flavors of workwear and outdoorsman lifestyles, inspiring legions of men to care more about fashion. Trim suits were paired with knit ties and gingham shirts, slim-fit chinos and capped with vintage-inspired Nike's. They mixed Red Wings with selvedge jeans and Barbour jackets. They re-wrapped these heritage brands in a modern context and introduced many men to niche brands like Alden, Chimala, and Anonymous Ism. Its own in-house take on workwear, Wallace & Barnes, also saw success for its range of chore coats and Japanese denim.
Though many flocked to J.Crew in its last wave of popularity have noted that the brand has seen its heyday, the future of J.Crew is still not set. Post-pandemic, we may still see J.Crew stores peddling Madras button-ups and brogues once again. But if that doesn't happen, there are still other places you can shop to get you the same fix.
It's clear that J.Crew took cues from Ralph Lauren. If you're looking for a one-to-one brand that offers the same range of goods that J.Crew does, Ralph may be the best brand to pivot to. They've clearly got the Ivy aesthetic with its button-down shirts, chinos and loafers. But Ralph also has its military and workwear streaks peppered throughout the collection, not to mention its indigo-soaked rugged line, RRL.
If you're looking for another brand that's one-to-one, Gap is a great alternative at a similar price point. While Ralph may be the source for many, its higher prices drove customers to places like J.Crew and Gap. Gap is known for its khakis, jeans and t-shirts, for sure, but they've also got a range of workwear-inspired goods that could scratch that itch. And, with the recent announcement of its partnership with Kanye West, the brand could see itself reinvigorated with an elevated casual look at a pricepoint that's familiar to the Gap customer.
An industry veteran, designer Todd Snyder has worked for big names like Ralph Lauren and Gap. He also was instrumental in J.Crew's success when he joined the brand in 2004. So if you liked J.Crew's designs and cuts anywhere from 2004 to 2009, you like Todd Snyder. His eponymous brand hits all the notes that J.Crew fans look for: tailored suits, cozy sweaters, niche third-party brands, Aldens, and more.
Hot on the heels of J.Crew's slump, Uniqlo's enjoyed great success since expanding its international market and opening its first U.S. store in 2005. The brand may generally lean more minimalist, or even somewhat hype (thinking of its range of graphic tees), Uniqlo is a go-to destination for solid basics as well as anticipated collabs with notable designers like JW Anderson.
More From Reports
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Workwear Is Back, but Not Like You Remember
This Great Summer Fabric Is Ancient
The Pillows of the Future Are Strangely Hands-On
Craft Brewers Are Running Low on a Vital Resource
How the Gay Community Helped Popularize Workwear
These Hiking Boots Broke My Sneaker Addiction
Just Getting Into Mid-Century Modern? Don't.
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Why Do People Go Crazy for Vintage Rolexes?
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PetPlanet LLC and Hachi Dog Grooming
11278 SW 137th Ave Kendall
FL, United States
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The Heatherley School of Fine Art, 75 Lots Road, Chelsea, London SW10 0RN | phone 020 7351 4190
Heatherley School of Fine Art
Diploma in Portraiture
Diploma and Post Diploma in Sculpture
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Heatherleys is situated on Lots Road, just off the Kings Road in west of Chelsea and close to the River Thames and Chelsea Harbour. London’s museums, galleries and theatres are all within easy access.
75 Lots Road, Chelsea, London SW10 0RN.
The nearest overground station is Imperial Wharf (5 minutes’ walk) and underground Fulham Broadway (12 minutes’ walk).
Secure parking is available in Edith Grove at £14 per day (five minutes walk from school). Please ask the office staff for more details and for a Heatherley ID card which you will need to present upon departure. LCP staff will provide you with a discount voucher to be used for future visits.
Find location and details of the Edith Grove car park here.
C3 – Lots Road (stops outside school)
11, 22 – Kings Road – World’s End Health Centre
328 – Kings Road – Gunter Grove
14, 211, 414 – Fulham Road – Hortensia Road
19, 49, 170, 319, 345 – Beaufort Street – Kings Road or Cheyne Walk
Fulham Broadway (District Line)
Imperial Wharf (4 mins to Clapham Junction)
RB6 – Alight at Chelsea Harbour: Thames Clippers
TFL Bicycle Hire
The nearest docking station for bicycles is in Upcerne Road near the junction with Lots Road.
Founded in 1845, The Heatherley School of Fine Art is one of the oldest independent art schools in Britain, and is among the few art colleges in Britain that focus on portraiture, figurative painting, printmaking and sculpture.
Heatherleys is controlled by The Thomas Heatherley Educational Trust.
Heatherley School of Fine Art is proud to be BAC accredited.
Heatherleys News
© 2016-2021 by Heatherley School of Fine Art
Information about lockdown January 2021
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About High Eye
AIRBOXER
Unmanned Helicopter System
The Airboxer is a long range unmanned helicopter with a three-blade single rotor. Because of its size, weight and capabilities, it creates a class on its own and brings industrial reliability into the UAV market in an unprecedented small size. High Eye believes its product should be safe to operate under nearly all circumstances and conditions, throughout the year. The Airboxer has been developed over a period of more than 6 years and has been tested under the most extreme conditions on several continents. It has been proven to deliver reliability and capability at any time, wherever it is needed.
The best way to understand the Airboxer and its capabilities, is by starting to imagine a down-sized version of a manned helicopter. A combination of well-proven aviation technology and modern materials, merged with state-of-the-art electronics, make the Airboxer what it is – an unmanned helicopter platform with global operational capabilities. The technical heart of the Airboxer is centered around the main drive-train, which is surrounded by the rotor systems, fuel system, avionics, sensors and a variety of antennae. The whole helicopter is engulfed by an aerodynamic composite shell, which also serves as the main support structure for all internal systems.
Drive Train and Rotor Systems
High Eye has chosen a classical main- & tailrotor layout for the Airboxer. The rotors have been designed for maintenance-free operation between overhauls, using fully sealed oil-lubricated bearing packs and abbrasion protected composite rotor blades. The main- and tailrotor gearboxes are based on over-dimensioned gear sets and titanium shafts, enclosed and environmentally sealed with permanent lubrication. Both the gearboxes and the rotor systems are rated and tested for a TBO of 1000 hours within standard operational conditions.
Powerplant and Fuel System
Propulsion is provided by an air-cooled boxer engine with fuel injection. Since operations at high altitudes and temperatures have been in mind from the start, the powerplant has a very high power rating for this size of airframe. The operation of the engine is monitored and controlled by a sophisticated ECU, which works in close harmony with the autopilot. The forced air-cooling allows continuous operations in hot & high conditions without negatively affecting the powerplant’s service life. The engine’s injection system is supplied with fuel by a maintenance free, redundant fuel pump module. The aircraft’s main fuel tank has a 6.5 liters AVGAS capacity.
Electronics and Avionics
All vital electronics on board the Airboxer are enclosed in a central module, located in the forward bay of the fuselage. The module protects the avionics from the outside world, including a high level vibration protection, MIL spec compliant EMI shielding and a dust- and waterresistant rating of IP-67. The very core of this module is formed by the autopilot, which is based on redundant CPUs and IMUs, cooperating with a third external IMU and a whole range of additional sensors. The module also contains the primary and secondary communications radios, the engine’s ECU, a back-up battery system and the alternator’s power convertor. The Airboxer’s alternator is mounted integrally in the main gearbox and powers all electronics and payload systems.
Sensors and Antennae
Although any UAV is full of sensors, High Eye has strived to keep this to an essential minimum. Sensory points of failure have either been reduced to the lowest possible level, or have been protected by a level of full redundancy. External sensors have been protected against EMI influences through shielding, filtering and software back-ups. The UAV’s flight control systems and communications equipment require a vast array of different antennae, which have been integrated into the airframe, reducing aerodynamic drag and improving the airframe’s ruggedness for transportation. Two in-house developed pitot tubes provide barometric inputs to the avionics and are electrically heated for in-flight icing protection.
Having had maritime operations in mind from the start, High Eye has taken corrosion protection to a class-leading level. Drive train components consist mainly of aircraft-grade titanium and surface treated aluminium. Sensitive components are environmentally sealed, whilst all fasteners are designed to reduce chances of contact erosion. The rest of the airframe mainly consists of composites and resiliant plastics. External electrical connectors and interfaces meet IP-67 requirements and tolerate saline conditions. External bearings and hinge points are largely based on industrial polymer bearings, allowing maintenance free operations in the toughest conditions.
Multi-Mission Capability
The combination of combustion engine technology, military grade communications equipment and clever design, make the Airboxer a real performer. It will come to its right within the widest variety of missions, be it long-range night-ops from a tactical vessel, to elaborate wild-life research mission in arctic regions. Its strength lies in the combination of long-endurance multi-sensor capability and the capability to operate basically from any area in the world – without additional hardware.
Endurance, Weight and Altitude
Taking ISA sea level conditions as the frame of reference, the Airboxer will lift payloads of 5.0 kilograms for several hours, at sea level. In the same environmental circumstances, it will be able to fly in excess of three hours at a speed of 30 knots with a payload of 2.0 kilograms, or accelerate onwards all the way up to 70 knots. The maximum take-off weight of the aircraft at sea level is 25.0 kilograms and is gradually reduced up to the rated service ceiling, at a density altitude of 10,000 feet.
Fuel Range and Radio Range
Any helicopter will see an improvement in fuel economy at a certain speed, the Airboxer will achieve its maximum range and endurance at a speed of 30 knots. At this speed it will be able to cover in excess of 180 kilometers on one fuel tank with a medium payload capacity. The primary communications data-link provides bandwidths in excess of 45 Mbit/s, and will still be able to achieve 10 Mbit/s at a clear line-of-sight range of more than 35 kilometers, retaining full high-definition video transmission capability.
Environmental Capabilities
The Airboxer’s flight control design and powerplant configuration allow the helicopter to be operated in a wide variety of environmental conditions. Standard operations are allowed in temperatures down to -20 degrees Celcius, up to 45 degrees Celcius and at a humidity of 95%. The UAV tolerates winds up to 25 knots for take-off and landing and moderate levels of rain, snow and hail. Electro magnetic interference has been demonstrated to pose no risk to the Airboxer at frequencies of 1 MHz to 18 GHz and field strengths of 200 V/m. When operating from a ship, roll and pitch angles of the deck are allowed up to 8 degrees and sea state 5 in standard operations.
Autonomy and Flight Modes
To adapt the system to ever-changing mission requirements, a variety of flight modes can be used to operate the Airboxer. All flight modes can be activated or changed at any time during flight. The autopilot provides both semi- and fully automatic flight modes, including multi waypoint following capability, automatic take-offs and landings and clearly defined back-up modes. The Airboxer can also automatically take-off and land on a moving ship, or follow a ship in a configurable orientation as it sails or changes course. In the event of a full loss of the redundant communication, the UAV is capable of following pre-determined routes, waypoints and altitudes, to bring it to an area which has been designated for the following automatic landing. Automatic navigation is made possible through a combination of barometric, magnetic and GPS based external inputs, and can be sustained at high accuracy when an input is lost. Multiple sensory failure leads to pre-defined flight modes which allow safe retrieval of the helicopter.
Flexibility by Design
Multiple payloads, sensors and other additional hardware can be integrated with ease on the Airboxer, to expand its capabilities and to fulfill a dedicated mission. Whilst some equipment is available as standard options, others can be integrated on request. The Airboxer is generously equipped for mounting odd-sized hardware to the airframe and to provide communication and electrical power for any UAV payload system within a certain weight range. Generally, payloads can be integrated with a total integrated equipment weight of up to 5.0 kilograms. A variety of different voltages and current ratings are supplied by the UAV’s electrical system to the payload. Depending on the final configuration and mission profile, payload communication data rates in excess of 30 Mbit/s can be handled by the Airboxer’s communication system.
Payload Integration
In the ever expanding market of UAV payloads, High Eye has chosen payload integration flexibility over offering a range of fixed payloads. Customers are free to select any third-party payload, as long as it fits the Airboxer’s payload capabilities. Over the years, High Eye has integrated different size stabilized payloads, with electro-optical, infrared and laser based sensors. A lot of experience has been built up to find the optimum in vibration-isolation without affecting the required high accuracy. Other integrated equipment includes Lidars, synthetic apperture radars, survey-magnetometers and gas detection equipment.
Airspace Integration
To aid integration on airfields and into controlled airspace, the Airboxer can be expanded with several compliant or certified aeronautical options. The MXS line of ADS-B In & Out transponders has been fully integrated into the UAV’s software. When the Airboxer is equipped as such, the transponder can be controlled through the GCS and transmit up to mode S. Standard options also include a full complement of FAR23 compliant aircraft lighting, including navigation/position lights, strobe lights and a beacon/anti-collision light. All lights can be controlled individually from the GCS during flight.
Maritime Operations
In the unlikely event of an emergency water landing, an automatically inflating flotation kit can provide much-needed flotation capability for the Airboxer. The optional automatic flotation bag inflates when beeing submerged and provides a highly visible reflective bag, to aid finding and recovery of the UAV from the water surface. For airline transport and long-term storage, the system can be de-armed. Other maritime payload equipment can include fully integrated AIS receivers or EPIRBs.
Ground Control Station & Communication
View ground equipment
Documentation, training, simulators and maintenance
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Cornelis Lelystraat 12
3316 ET Dordrecht
Email: info@higheye.com
Navigate: Google Maps
Downloads / Media
© 2020 HighEye
On top of tests, client cases, distribution network and Trade Shows
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Hot Topic Friday: March, 29 Newsletter
Abundance Accountability Personal leadership Respect
Happy Friday everyone! Here are some Hot Topics that caught my attention this week.
Hop Topic 1: Hilton Named No. 1 Company on Fortune’s 100 Best Companies to Work For List
What it’s About:
Fortune published its Best Companies list. Check out the following from Hilton President and CEO, Chris Nassetta. He notes, “We lost our way a bit…We forgot that we are a business of people serving people, and the corporate environment got very disconnected from the front line.” Under Nassetta’s guidance, Hilton launched an expansive program to upgrade “back-of-house” areas used by staff, and introduced many other employee focused changes.
Why it’s Important:
Organizations sustainably thrive when they really get the people side of the business right. With the stock up 274 percent from its IPO price in 2013, you gotta believe that Hilton’s investors are cheering the employee-first philosophy the hotel has executed on. Every organization can learn from what the great ones do. The Top 100 Best Companies to Work For list offers a roadmap to become culturally and financially better.
Hot Topic 2: Human Contact is Now Considered a Luxury
Reporter Nellie Bowles points out that screens used to be exclusive to the elite. Nowadays, avoiding them is a status symbol and makes the argument that human contact is rapidly becoming a luxury good. She shares a “WTF” story of a 68-year-old lonely man, whose life is emotionally richer through his relationship with a virtual, avatar cat named Sox that lives on his tablet. It’s what he can afford. At the opposite end of the rich scale, and in unabashed irony, the wealthy of Silicon Valley are paying huge dollars to send kids to screen-free schools.
I do not want to minimize or judge the special relationship between a virtual cat named Sox (being controlled from a remote destination), and the “master” human being sitting on a couch. However, when human contact becomes something for the rich only, we might have a BIG problem. Work, although allowing for much more remote and gig experiences, must make room for our human need to be with each other. Let’s keep an eye on this trend.
Hot Topic 3: WeWork Loses Billions and is Excited About It
The co-working company disclosed on Monday that its losses more than doubled last year to about $1.9 billion, even as its total revenue also expanded to about $1.8 billion. It will not slow down it’s breakneck, worldwide growth and the President, Artie Minson, believes it can get profitable as it needs to. The company also feels it can withstand a recession because organizations will move to more variable space commitments; WeWork’s wheelhouse. In eight years, it has grown to a company valued at $42 Billion USD with 401,000 paying members. Wow!
This underscores the reality of the gig economy and signals the way many organizations are re-thinking the physical work space. My co-author Garrett worked in a WeWork space in LA and asked in a previous blog, “What if many traditional organizations like post-secondary institutions started using space like the ones offered by WeWork?” Hmm.
And finally! Here’s Cecil’s Bleat of the Week!
“Today’s leaders must be willing to take on the job of driving fear out of the organization to create the conditions for learning, innovation, and growth” – Amy C. Edmondson, from her book, The Fearless Organization.
– Lorne Rubis
Incase you missed it:
Monday’s Lead In podcast.
Tuesday’s blog.
Wednesday’s Culture Cast podcast.
Also don’t forget to subscribe to our site, and follow Lorne Rubis on Instagram, LinkedIn, Facebook and Twitter for the latest from our podcasts, blogs, and all things offered on LorneRubis.com.
Culture Cast – What Being ‘People First’ Really Means
Personal leadership Podcast
In season 3, episode 8, Lorne and Lynette discuss being “People First,” and what the heck that really means.
Too many leaders are still focused on being “customer first.” While it’s important to be customer obsessed, we discuss the extreme value that organizations experience when they provide the best conditions for the PEOPLE that work there.
Sure, work perks like pizza, pets and casual dress codes are nice… However, Lorne and Lynette focus on steps and ideas that leaders can take to provide an environment that gives employees the chance to be fired up about what they do, and achieve results that WOW. Being People First doesn’t mean you are not also simultaneously customer obsessed.
Leaders can put together the tools, time, opportunities and purpose to make going to work a passionate and PEOPLE FIRST experience.
Please feel free to subscribe to this YouTube channel, follow this podcast on Soundcloud, as well as iTunes, and Lorne and Lynette’s social media platforms for all the latest Culture Cast uploads and announcements.
Lorne Rubis is available @LorneRubis on Instagram, Twitter, LinkedIn and Facebook.
Lynette Turner is available on Instagram, Facebook, LinkedIn as well as through her site, LynetteTurner.com.
We look forward to sharing Season 3 of Culture Cast: Conversations on Culture and Leadership with you every Wednesday.
Who Keeps Glassdoor Scores?
The Challenge: Glassdoor is the Yelp of the workplace, and the reviews your company receives really matter. Salesforce.com is arguably the No. 1 large company to work for in the world. Their Glassdoor approval score is 4.4/5, and 89 percent would recommend the company to a friend. Marc Benioff, the CEO, has an approval rating of 98 percent. During the five years I spent as CPO at ATB Financial, our score was consistently 4.4, and CEO Dave Mowat had a 99 percent approval rating, the highest of all Glassdoor companies with more than 5,000 employees in the world. That’s a WOW!
Salesforce.com analyzed both employee turnover and recruitment success. Here’s what they found out: The great people who left, went to companies with a higher Glassdoor score, and they attracted top people from companies with scores lower than Salesforce. It was that clear, and subsequently they pay very close attention to their Glassdoor status.
The Solution: When I ask a lot of people what their Glassdoor score is, many still say “huh?” Too many people are unfamiliar or ambivalent. Here’s an article covering companies with over 5,000 employees who have the worst Glassdoor scores in 2019. The average overall score (among almost 50,000 organizations) is 3.4/5. Crappy companies are in the 2.0’s. If you read this statement about your company or one that you might be interested in joining, what would you think?: “There is a lack of stability and ongoing headcount cuts makes for bunch of unease. Constantly getting new managers as everyone leaves or gets let go so creates a constant starting from scratch. Very negative management style seems to be the normal. Plant closures has begun and maybe to continue so is gloomy as there is a sense of defeat and don’t [sic] get feeling that there is proper plan.” This is a direct quote from one of the sucky companies. I could have picked much worse.
What we can do about it?
If you’re a leader, have a game plan to get the score over 3.4 (unless you like being average). The best organizations strive to stay over 4.0. Be aware of the comments on Glassdoor. Don’t overreact to one off “haters,” but the trend is your friend or not! Take proactive action.
If you’re a team member, be aware of what people are saying about your company and be prepared to honestly post about your workplace. Insist that the company pays attention to the comments. It’s an important listening post!
Go to your Glassdoor score now and find out.
Think Big, Start Small, Act Now,
One Millennial View: A great score on Glassdoor is a nice badge of honor. While it’s imperfect, and could be potentially infiltrated by bots, it’s one important data source. Since every organization is invited and joining the Glassdoor party, you might as well strive to be a highly rated guest (and skipping the invite isn’t a good look either).
– Garrett
Edited and published by Garrett Rubis
Lead In With Lorne – Here’s When You Shouldn’t Rescue People
In this episode of Lead In With Lorne, if someone needs rescuing when they could be really hurt, then do so. However, if not, don’t plow everything out of the way for them. Here’s a personal story and a valuable learning lesson regarding self-accountability, and the importance of letting people figure it out and rescue themselves when you’re confident they can. Both parties benefit from embracing the struggle. Let people find their way. Watch/listen to get the full story.
Enjoy it on the YouTube video embedded below, or audio listeners can hear it on SoundCloud now too (iTunes coming in the near future). We hope it enriches your Monday!
Kindly subscribe to the YouTube channel and SoundCloud to make sure you start your week with a leadership story.
Happy Friday everyone! I wanted to share with you some HOT TOPICS that have caught my attention this week.
Hot Topic 1: Goldman Sachs CEO reveals the valuable job skill he now struggles to find.
CEO David Solomon talks about what Goldman is looking for in talent that may surprise you. The following quotes are instructive:
“’I’ll tell you one that we’re finding less and less inside the firm that I think is an important skill set… Is an ability to write,’” – Solomon in response to a question from Yahoo Finance.
“’The other thing I’d point to that’s so important is there is a real emphasis when people are interviewing around academics and I.Q. I think it’s way overweighted… There should be equal emphasis on E.Q. and how you interact with people, how you relate to people, and how you connect with people.’”
Goldman arguably hires to the “best and brightest.” They are totally a service business based on applying top talent. When Solomon says they’re giving more attention to writing skills and EQ, it reminds us that these are important areas even bankers should personally invest in.
Hot Topic 2: The 8-Year-Old Homeless Refugee Chess Champion.
NYT opinion columnist Kristof reports on a story of how we can overcome circumstance to excel. Tapping into our passion and aptitude within a supportive environment is a winning combination.
“In a homeless shelter in Manhattan, an 8-year-old boy is walking to his room, carrying an awkward load in his arms, unfazed by screams from a troubled resident. The boy is a Nigerian refugee with an uncertain future, but he is beaming. He can’t stop grinning because the awkward load is a huge trophy, almost as big as he is…This homeless third grader has just won his category at the New York State chess championship… What’s even more extraordinary is that Tani, as he is known, learned chess only a bit more than a year ago. His play has skyrocketed month by month, and he now has seven trophies by his bed in the homeless shelter.”
Much of the news last week focused on wealthy families buying access to great universities, either illegally through bribes or legally through donations. This put a bad taste in our mouths. We need Tani stories, and to fight for the benefit that comes from the struggle. Tani wasn’t “rescued” by so called “bulldozer” parents. He was given the opportunity and HE did it. Whether at home or work, let’s not rob people we care for of the bumps. They build character and ultimately confidence… But not when we rush in to take away the pain associated with learning.
Topic 3: The Right Way to Follow Your Passion.
There is lots of discussion about the importance of being passionate as a vital and distinguishing characteristic. Yet, there is a difference between harmonious and obsessive passion. Passion should not be valued as “good” by default. NYT contributor Brad Stulberg says,
“Put simply: Passion can be a gift or a curse… The good news is that the form it takes is largely up to you… Jeff Skilling, of Enron, and Elizabeth Holmes, of Theranos, oversaw two of the biggest corporate frauds in recent American history. Before the scandal-ridden downfalls of their companies, both were widely celebrated for their passion and obsessive drive, something Ms. Holmes said was a most important asset. Alex Rodriguez and Lance Armstrong, two of the most notorious cheaters in sports, were also two of the most passionate competitors… What all of these individuals have in common is that their passions went awry because of an incessant focus on results, results, results. When the results weren’t meeting their exceedingly high expectations, they turned to unethical behavior to close the gap.”
There is an argument for results being everything. And yes, leaders must get results, but NOT without the guidance of values that advance humankind. Stulberg notes: “Obsessive passion — fueled by a longing for external results, recognition and rewards — trouble lies ahead. That’s because people typically crave more. More money. More fame. More medals. More followers.” When we focus with meaning, deep purpose and have harmonious passion, it often leads to great results, but not at the cost of our decency.
And finally! We’d like to introduce you to our mascot, Cecil.
Here’s Cecil’s Bleat of the Week:
“The greatest life-lie of all is to not live here and now.” Excerpt from
The Courage to Be Disliked by Ichiro Kishimi & Fumitake Koga.
Incase you missed it!
Culture Cast – Peer-to-Peer Leadership Works Best in Today’s Organizations
In season 3, episode 7, Lorne and Lynette discuss moving away from command and control in leadership to make an even bigger, more effective impact with a peer-to-peer system.
Organizations are simply moving too fast for traditional leadership systems to be as efficient and effective as they need to be. Both leaders and team members should be comfortable enough to let go and adopt peer-to-peer models that work.
Team members are hired to be free-thinkers and creators, and it’s their responsibility to look for opportunities to contribute to solving big issues at work, not just doing assigned transactions. Abandon the “what are they going to do about it?” and “that’s not my department” attitude.
When team members’ ideas can get out and be implemented, they can be put into the community so it becomes a bigger and better idea, which is more gratifying for both the individual and the organization as a whole.
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High Rated Gabru
DRUGS AND MEDICATION
Disease » Hepatitis-A : Causes, Diagnosis, Treatment and Vaccination
Hepatitis-A : Causes, Diagnosis, Treatment and Vaccination
Hepatitis A disease can be unpleasant, but it’s not so serious and most of the people make a full recovery within a couple of months. Hepatitis A vaccines are normally used to prevent hepatitis A, a type of liver disease that is caused by the hepatitis A virus (HAV or Hepatovirus A).
Some people, particularly young children, may not have any symptoms of this disease.
Hepatitis-A Virus : Fast Facts
HAV was first identified in 1973
HepA is a viral liver disease that can cause mild to severe illness
It can be passed on between people or through contaminated food or water
A person can have Hepatitis A virus without showing its symptoms
Hepatitis A vaccines are the most effective ways to combat the disease
What Causes Hepatitis-A?
A person with Hepatitis A virus will excrete the virus in the feces or stool. It can be passed on when an uninfected person consumes water or food that has been contaminated with the feces of an infected person.
Hepatitis A infection can be mild with no symptoms or a serious illness that can rarely cause liver failure and death. Getting vaccinated against the hepatitis A virus is the best way to prevent these problems.
How To Diagnose Hepatitis-A Disease?
A blood test can confirm an infection with Hepatitis A virus (HAV). Antibodies can detect both acute infection and a past infection.
An unpleasant infection with Hepatitis A virus (HAV) should be reported to local public health authorities to help prevent the disease from spreading further.
How To Cure Hepatitis-A?
There is no specific treatment of Hepatitis A disease, but a supportive therapy can improve the comfort levels and prevent the complications such as exhaustion and dehydration. This includes —
Avoiding alcohol
Rest, with time off work
Replenishing nutrition and fluids
Taking over-the-counter (OTC) pain relievers (if necessary)
Patients with significant nausea and vomiting may be admitted to the hospital for intravenous (IV) fluids.
There are no complications and most of the people get recover fully. Around 85 percent people infected with hepatitis A virus (HAV) get recover fully within 3 months, and most people have complete recovery by 6 months.
Hepatitis-A Vaccination
Hepatitis A vaccination works by stimulating the body to produce antibodies, which are basically the proteins that will fight and kill the virus of hepatitis A disease. Hepatitis A vaccine was approved in 2005.
Havrix and Vaqta are the brand names, available for hepatitis a vaccine-injection.
Children should receive a set of HepA vaccine series starting at 12 to 23 months, separate the 2 doses by 6 to 18 months. Children who’ve received 1 dose of HepA vaccine before age 24 months should receive a second dose 6 to 18 months after the first dose.
For all persons aged 2 years and older who hasn’t already received the HepA vaccine series, 2 doses of HepA vaccine separated by 6 to 18 months can be administered if immunity against hepatitis A virus infection is desired.
Hepatitis A Vaccination is recommended for any person seeking protection from hepatitis A virus infection and persons with any one of the following indications —
Men who’ve sex with men and people who use injection or non injection illicit drugs
Persons working with HAV infected primates or with HAV in a research laboratory setting
Persons with chronic liver disease and persons who receive clotting factor concentrates
Persons traveling to or working in nations that have high or inter mediate endemicity of hepatitis A
Unvaccinated persons who expect close personal contact with an international adoptee throughout the first sixty days after arrival in the US from a country with high or intermediate endemicity
The first dose of the 2 dose hepatitis A vaccine series should be administered as soon as adoption is planned, ideally 2 or more weeks before the arrival of the adoptee. Single antigen vaccine formulations should be administered in a 2 dose program at either 0 and 6 to twelve months, or 0 and 6 to 18 months.
Both vaccines are inactivated and have age based dosing schedules. They’re approved for people aged twelve months and older. An inactivated hepatitis A and B combination vaccine, Twinrix, was licensed in the year 2001 for persons older than 18 years.
Twinrix can be used on an accelerated schedule for persons susceptible to hepatitis A and B who’re planning imminent travel to endemic areas.
The hepatitis A vaccine shouldn’t be given to patients who’ve had a severe allergic reaction following a previous vaccine dose or to a vaccine component.
Vaqta shouldn’t be given to subjects with a neomycin allergy. The tip caps of prefilled syringes for Havrix might contain natural rubber latex, patients allergic to latex should be given Vaqta with caution.
A vaccine, like any medicine, could possibly cause severe problems, like severe allergy.
What Are The Side Effects Of Hepatitis-A Vaccine Injection?
Mild side effects include —
Soreness where the shot was given
Other reported side effects include —
Hepatitis A virus (HAV) is an acute infection that affects human liver. It can last for few weeks or several months.
Getting vaccinated against the hepatitis A virus (HAV) is the best way to prevent these problems.
Havrix and Vaqta are the brand names, available for hepatitis a vaccination.
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SECTOR — 36, GATE NO. 4, GREATER NOIDA, UTTAR PRADESH, INDIA — 201306
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Midwest Family Farm Groups Want Aid to Get to People, Not Global Agribusiness
The Campaign for Family Farms & the Environment (Missouri Rural Crisis Center, Iowa Citizens for Community Improvement, Dakota Rural Action, Land Stewardship Project, Food & Water Watch, and the Institute for Agriculture and Trade Policy).
Groups Concerned That Trump’s USDA Will Continue to Favor Industry
Family farm based organizations in Iowa, Minnesota, Missouri and South Dakota sent a letter to Congress today calling for strong oversight of the recently passed COVID-19 aid package to ensure the U.S. Department of Agriculture (USDA) disburses aid to people and rural communities, not global agribusiness firms that reaped tens of millions of dollars from recent trade-aid payments.
In the letter, the Campaign for Family Farms and the Environment (CFFE) urged Congress to set up guardrails for USDA regarding a total of $24 billion in aid designed to support farmers hurt by the enormous disruption in markets and supply chains caused by the COVID-19 outbreak. Specifically, CFFE called for: no public money to go to new or expanding confined animal feeding operations (CAFOs), which have flooded the market, driving farmers’ prices for livestock and milk down while polluting rural waterways; a prohibition on multinational agribusiness firms from receiving aid; and adequate resources for farmers supplying local markets that have disappeared.
“Family farmers and communities in rural Missouri and rural America are stressed to the max,” said Darvin Bentlage, cattle and grain farmer from Southwest Missouri. “We need help, and Secretary Perdue has a moral imperative to direct public stimulus funds to family farms and businesses on our rural Main Streets. He should pretty much do the opposite of what he did in the Market Facilitation Program where millions and millions were given away to corporate and foreign agribusiness and factory farm corporations.”
"This crisis will produce more bailouts and more policy initiatives," said Darrel Mosel, a grain-livestock farmer and Land Stewardship Project member from Central Minnesota. "The focus needs to be on long-term positive changes to our farming system, like support for local and regional food systems. But a blank checkbook approach for the rest of that money is a path towards more of the same — decimated rural communities, dirty water and a food system controlled by fewer and fewer players.”
As Congress considers a new stimulus package, CFFE pointed to the urgent need to address structural failures in agricultural markets that prevent farmers from making a fair living. CFFE highlighted the need for a two-year suspension of loan payments; a halt on loans for new or expanding CAFOs; a moratorium on new agribusiness and food industry mergers; stronger fair market practices rules; enabling access to safety net programs for farms and small food businesses; and mandatory Country of Origin Labeling (COOL).
“Corporations do not need a bailout right now. Family-scale farmers and ranchers that produce for regional communities need assistance,” said Stephanie Peterson, Dakota Rural Action Board member and owner of Fruit of the Coop in Sioux Falls, South Dakota. “This current crisis has highlighted, more than anything, the need to reduce our dependence on large corporate food distribution systems. We should be focusing on local and regional food operations and supporting our local producers and consumers during this time of hardship and upheaval. How can we be more resilient as a community? One of those ways is to get to know the folks producing our food and buy directly from them.”
“On top of not getting a fair price for what they produce, family farmers are now dealing with the impacts of a global health pandemic. When farmers are forced to keep producing to try to get by, the factory farm industry benefits from the cheap grain prices,” said Larry Ginter, a family farmer and Iowa CCI member from Rhodes, Iowa. “Just like we don’t need to produce cheap grain for the factory farm industry, we don’t need to bail out this corporate controlled industry. USDA dollars must go to independent family farmers, not factory farms.”
The full letter to Congress is available here.
The Campaign for Family Farms & the Environment (CFFE) is composed of the Missouri Rural Crisis Center, Iowa Citizens for Community Improvement, Dakota Rural Action, Land Stewardship Project, Food & Water Watch, and the Institute for Agriculture and Trade Policy.
Download the PDF of the release here.
PRESS RELEASE_CFFE Wants Aid to Get to People Not Global Agribusiness_April 2020.pdf155.84 KB
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Bengal Global Industrial Summit: Centre will stand by West Bengal, says Jaitley - Part 1
Kolkata, Jan 07 (ANI): Union Finance Minister Arun Jaitley while addressing 'Bengal Global Business Summit, 2015' in Kolkata on Wednesday said that the Central government will stand by West Bengal government as far as its industrial climate is concerned. Jaitley said that Bengal has several strengths like its strategic positions, its intellectual capital and rich mineral resources, but unfortunately many big industries have shifted out from the state. So, the biggest challenge is to establish them once again. Jaitley said that like Prime Minister Narendra Modi had once said he also believed that eastern India should grow faster than the country's western parts. Jan 7, 2015
Sri Lankan President Rajapaksa's Astrologer Predicts 'Big Victory'
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Sriharikota on Terror Alert as Police Launch Manhunt for 5 SIMI Members
Security in and around Sriharikota, including Sriharikota Range (SHAR), Indian Space Research Organisation's (ISRO) Satish Dhawan Space Centre and other vital installations has been beefed up. Jan 7, 2015
26/11 Mastermind Lakhvi to Remain in Jail as Pakistan SC Terms HC's Bail Order Void
Lakhvi was to be released on 30 December after Islamabad HC suspended his detention orders in connection with the 2008 Mumbai terror attacks. Jan 7, 2015
North Korea Readies 6,000-Strong 'Cyber Army' to Paralyse South
The latest figure is double of what Seoul estimated in 2013, and was disclosed in a ministry white paper. Jan 7, 2015
Threat Message Scribbled Inside Mumbai Airport Toilet Warns of 'Terror' Attack by ISIS on 10 January
Security measures across the country have been beefed up especially as there have been a spurt in terror threats ahead of US President Barack Obama's India visit on 26 January. Jan 7, 2015
Sunanda Puskhar Murder: Conspiracy Theories Range from ISI Agents to Dawood Gang
The mention of polonium as a possible poison used in Pushkar's murder has led to speculations of the role of a 'highly-placed' and probably 'foreign' person or agency. Jan 7, 2015
TV Channels Air Sunanda Pushkar's Corpse Images, Cause Outrage on Social Media
Several news channels were criticised by the audiences for their lack of 'sensitivity'. Jan 7, 2015
Orthodox Christmas Day 2015: Quick Facts about the Observance of Eastern European Churches
Many orthodox Christians from around the world celebrate the Christmas Day on or near January 7. Jan 7, 2015
Palestine to Join International Criminal Court in April, Set to Put Israel in Dock for 'War Crimes'
Palestine had ratified the Rome Statute last week. Jan 7, 2015
Minor girl allegedly sexually assaulted at school in Bengaluru
Bengaluru, Jan 07 (ANI): A minor girl was allegedly sexually assaulted at school in Bengaluru on Wednesday after which agitated locals protested and destroyed school property. Bengaluru Police Commissioner MN Reddi said that the girl was allegedly assaulted by the physical education teacher in the school. He assured that police will take the necessary action in the case and appealed to the locals not to spread disharmony in the area or cause violence. Jan 7, 2015
Vinay Katiyar says 'ghar wapsi' won't succeed if Hindus don't change their mindset, Politicos react
New Delhi, Jan 07 (ANI): Political leaders on Wednesday react as BJP Rajya Sabha member from UP, Vinay Katiyar said that 'ghar wapsi' won't succeed if Hindus don't change their mindset. BJP Spokesperson GVL Narasimha Rao said that BJP is not involved in such programmes and distanced the party from the same. He also said that the central government had proposed a law against the same which still remains pending. Congress leader Rita Bahuguna Joshi and JD (U) leader Ali Anwar condemned the programme and said that such programmes should be avoided. Jan 7, 2015
Bengal Global Industrial Summit: Political differences won't block development, says Mamata
Kolkata, Jan 07 (ANI): West Bengal Chief Minister Mamata Banerjee on Wednesday invited industrialists from across the world to invest in the state and assured them all help in establishing their businesses. While addressing business heads from all around the world after inaugurating the two-day Bengal Global Business Summit along with Union Finance Minister Arun Jaitley promised a business-friendly environment in the state. She assured that political differences will not block the road for development. Jan 7, 2015
Punjab CM demands release of Sikh terrorists, Reactions flow
New Delhi, Jan 07 (ANI): Punjab Chief Minister Prakash Singh Badal has written in a letter to many states demanding the release of 13 Sikh terrorists involved in Khalistan activities. This drew reactions on Wednesday from political and anti-terrorist organizations. NCP leader Majid Memon said that this is a matter which should be treated or released under law. BJP leader GVL Narasimha Rao said that political parties should not use terror to hold votes. Congress leader Abhishek Manu Singhvi said that it was a matter to be dealt between law and government. Meanwhile, AIATF Chairman Maninderjeet Singh Bitta said that terrorists should never be freed from jail. Jan 7, 2015
Every Hindu Woman must Produce 4 Children to Protect Hinduism: BJP's Sakshi Maharaj
Sakshi Maharaj requested Hindu woman to give away one child to religious leaders and send another one to the borders. Jan 7, 2015
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Senior & Veterans Services
Yellow Ribbon Campaign
Inver Grove Heights, a Yellow Ribbon City
The mission of the Inver Grove Heights Beyond the Yellow Ribbon Campaign is to provide the community a network of support for military members, veterans and their families before, during and after deployment.
The Minnesota National Guard has pioneered a program which empowers community leaders to synchronize efforts and build an enduring network of support for service members and families throughout the deployment cycle.
A Core Committee meets at 6:00 pm the first Monday of each month at the Armory end of the Veterans Memorial Community Center. The group plans and reviews upcoming activities to maintain Beyond the Yellow Ribbon designation for the City of Inver Grove Heights.
The committee strives to maintain a volunteer support structure for military members and their families that includes simple acts of kindness, like snow-shoveling, lawn mowing, painting, occasional meals or childcare.
Please contact Janet Shefchik, 651-450-2512, or jshefchik@invergroveheights.org if you would like to volunteer your time or have a group looking for a meaningful way to support your community.
Please visit the Beyond the Yellow Ribbon website for more information.
Dakota County Senior Housing Program
Senior Center and Senior Club
Senior Transportation
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United States Ambassador to the United Kingdom, Walter Hines Page to Secretary of State Robert M. Lansing
TELEGRAM RECEIVED
Dated July 5, 1917
Rec’d. July 5, 3:15 P. M.
Secretary of State,
6644, July 5 9 a. m.
Strictly confidential, to the President and the Secretary.
A threatening controversy is going on in the British Cabinet about the proper attitude towards the submarine peril. The Admiralty faction, whose facts which are indisputable have been cabled to you, take a very gloomy view of situation and insist upon Cabinet’s making a confession at least to us of the full extent of the danger and on giving more information to the Public. The public has been kept in too great ignorance to feel alarm. The political faction which is yet the strongest, minimizes the facts and probably for political reasons refuse to give more publicity. They plead the necessity of exclusion full facts from the enemy and the danger of throwing the public into panic. The Prime Minister who is always optimistic and who seems to yield his judgment to political motives gave the public in his Glasgow speech a comforting impression of the1 situation, and impression that the facts do not warrant.2 This facti[o]nal controversy is most unfortunate and may cause an explosion of public feeling at any time and consequently changes in the Cabinet. If the public here or in the United States knew all the facts the present British Government would probably fall. The Political situation here as well as the submarine situation is therefore full of danger.
P A G E.
Source Note: Cy, DNA, RG 45, Entry 517. In the top right hand corner of the second page “From London #5544 is written but it is believed that 6644, the document identifying number, was intended.
Footnote 1: The word “situation” is written below the final line on the first page below this sentence to preview the first word of the next page.
Footnote 2: Prime Minister David Lloyd George. The Glasgow speech mentioned is a speech Lloyd George gave on 29 June 1917 entitled, “When will the war end?” This speech urged the British people to support the war until the allies achieved their war aims, and downplayed the impact that the German U-Boats were having. David Lloyd George “When Will the War End?” London: Labor Party, 1917.
Walter Hines Page, Robert M Lansing
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How toGaming
Well, first of all, let me tell you what type of game, Terraria is. To begin, it’s a 2D game filled with adventure and you explore different places. So, for those who love exploring and traveling, nothing is better than this game. This updated game has more than 2500 items in Terraria. It’s something that grooms you, helps you to manage yourself independently where you beat the bosses, go for building infrastructures, collect the weapons and tools, and a lot more to do. The most interesting fact is that this game has sold around 12 million copies which, of course, is not a small deal. Although it costs 10 dollars, the game is worth it.
This game has fortunately completed it’s seven years of success and it can easily be modified as per your wish. There are hundreds of mods available, out of which we will be telling the best ones. Sometimes, it’s human nature that we get tired playing the same game again and again, hence, installing these mods will change the game for you and surely, will make the game more interesting for you. Try it!
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How to Install Terraria Mods?
Not to make this piece of information more technical for you, we’ll inform you How to install these mods?
In order to install these mods, you will have to download an application called the tMod Loader. Now, what will it do? It will basically add another item in your game’s main menu and that is Mod Browser from where you can search all the great mods you want for your game and enjoy!
Now, coming to the main point What are the best Terraria mods in 2020?
Below you’ll find the list of must-have Terraria mods.
1. The First Mod is “Start with Base”
It gets quite irritating when you’re making a base every time you start a new game. It wastes your time and gets boring too. Therefore, this start with base mod helps you to make this game faster as whenever you’ll start a new game, the base will be there and no time wastage.
2. The Second Best Mod is the Recipe Browser
It takes a lot of time to learn the recipes of different items and it’s quite difficult too. Therefore, if you want to get rid of it, then this Recipe browser mod is the best thing you can have. Instead of searching through the wiki, you can easily download it and this will help you to search any recipe you wish to see with the name of the item. This mod also has a database and descriptions.
3. Another Best Mod is Reduced Grinding Mod
This mod is basically for the ones who feel frustrated while grinding for a long time and finding the rare items can be boring too. Hence, just like the name of this mod, it can easily increase the rate of grinding and can skip several bring events related to grinding.
4. Then Comes the imkSushi’s Crafting Mode
Here, it’s again for the ones who hate grinding. Although you have the reduced grinding mod, but this one allows you to make your game more engaging by letting you craft according to your wish and also enables you to summon the bosses again that you have previously defeated if you like fighting or action. Then it also adds several different kinds of recipes along with new items.
5. Terraria Magic Storage is Another Best Mod of Terraria
While playing this game, Terraria, you keep on collecting many items and several different things. It can be a headache for you to keep a check on these storages and can create a lot of confusion. Hence, as a result, we have this Terraria Magic storage that enables us to create the main network that will allow us to go through our items on a single block. We can also search for them with the help of its name or the type of the item.
6. We also have a Cheat Sheet in Terraria
Now, what is this cheat sheet? This mod helps you to create your own places on the map or copy-paste the places on the map wherever you like in order to make it more engaging. It helps you to rearrange the game’s assets and enhance your creativity.
7. Thorium; The biggest Mod of the Game
Personally, it’s my most favorite mod and there’s a reason behind it. This mod helps to completely change the game according to you as it can add 1800 items more and more than 50 sets of armors. It can also help you introduce 11 new bosses and more than 150 enemies which makes it more challenging and tricky. Therefore, this mode will be your most favorite too if you try it once.
8. Terraria Overhaul
This mod helps you to add a new game playing style and remakes the existing items in the game rather than introducing new components or items. It basically changed the framework of the game and makes it more simple by just renewing the items rather than adding more and making it more complicated.
9. Calamity
is also one of my favorite mods which I think is also one of the best mods of Terraria just like the Thorium. This mode enables us to play the game with hundreds of enemies and around 22 new bosses giving us the opportunity to have amazing abilities to fight. After playing the native game if you get tired, you can try this mod which adds many more new items and makes the game totally different.
10. Tremor
stands beside Thorium giving us the chance to play this game for a longer time with an abundance of items and more than 20 new boozed along with more invasions. So, if you’re a big fan of this game, you shall definitely try this.
11. N Terraria
So, the last mod that we are going to mention is N This mode is quite different from the others, it brings along many different races and classes which eventually leads to the addition of different levels and makes this game more interesting and capture the player’s attention who does not feel like to end the game.
So, these were some great and best modes of Terraria 2019. We have tried all our best to guide you as simpler as we can. You can download these mods for free and easily as per the application mentioned above. Hopefully, you liked it!
Terraria Mods
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February 10, 2020 pawan0866
Compound found in these vegetables may help fight fatty liver disease: Study
By: PTI | Houston |
Published: February 10, 2020 11:50:57 am
The researchers investigated the effects of indole on individuals with fatty livers. (Photo: Getty Images/Thinkstock)
A natural compound found in widely consumed vegetables such as cabbage, kale, and cauliflower may help treat fatty liver disease, a study claims.
The study, published in the journal Hepatology, demonstrates how non-alcoholic fatty liver disease (NAFLD) can be controlled by indole, a natural compound found in gut bacteria, and in cruciferous vegetables.
It also addresses how this natural compound may lead to new treatments or preventive measures for NAFLD, the researchers said.
“We believe healthy foods with high capacity for indole production are essential for preventing NAFLD, and are beneficial for improving the health of those with it,” said Chaodong Wu from Texas A&M AgriLife Research in the US.
“This is another example where altering the diet can help prevent or treat disease and improve the well-being of the individual,” Wu said.
NAFLD occurs when the liver becomes “marbled” with fat, sometimes due to unhealthy nutrition, such as excessive intake of saturated fats.
If it is not properly addressed, the condition can lead to life-threatening liver disease, including cirrhosis or liver cancer, the researchers said.
Gut bacteria can have an effect — either positive or negative — on the progression of fatty liver disease, they said.
These bacteria produce many different compounds, one of which is indole.
This compound, a product of the amino acid tryptophan, has been identified by clinical nutritionists and nutrition scientists as likely having preventive and therapeutic benefits to people with NAFLD.
The US National Cancer Institute also notes the benefits of indole-3-carbinol found in cruciferous vegetables, including their anti-inflammatory and cancer-fighting properties.
The latest study examined the effect of indole concentrations on people, animal models, and individual cells to help determine indole’s effect on liver inflammation and its potential benefits to people with NAFLD.
It investigated the extent to which indole alleviates NAFLD, incorporating previous findings on gut bacteria, intestinal inflammation, and liver inflammation.
The researchers investigated the effects of indole on individuals with fatty livers.
In 137 Chinese subjects, the team discovered people with a higher body mass index tended to have lower levels of indole in their blood.
The levels of the compound in those who were clinically obese were significantly lower than those who were considered lean, the researcher said.
In those with lower indole levels, there was also a higher amount of fat deposition in the liver, they said.
“This result will likely extend to other ethnicities, though ethnic background may have some influence on gut bacteria populations and the exact levels of metabolites,” said Qifu Li, also a physician at Chongqing Medical University in China.
To further determine the impact of indole, the research team used animals fed a low-fat diet as a control, and high-fat diet to simulate the effects of NAFLD.
“The comparisons of animal models fed a low-fat diet and high-fat diet gave us a better understanding of how indole is relevant to NAFLD,” said Gianfranco Alpini, a former professor at Texas A&M Health Science Center.
Alpini, now the director of the Indiana Center for Liver Research, said treatment of NAFLD-mimicking animal models with indole significantly decreased fat accumulation and inflammation in the liver.
For all the latest Lifestyle News, download Indian Express App.
Tagged fatty liver disease, fatty liver disease indian express, fatty liver disease study, fatty liver disease symptoms, fatty liver disease treatment, how to fight fatty liver disease, indian express news, vegetables that help fight fatty liver disease, what is fatty liver disease
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Site New Answers Search Boards ILE ILM Answers New Question New Questions New Poll Blog View Register Login
Tango in the Night POLL (Fleetwood Mac)
I take a crack at it. Thanks, thread!
― the Rain Man of nationalism. (Alfred, Lord Sotosyn), Friday, 31 March 2017 01:42 (three years ago) link
Whenever I sing the chorus of 'Little Lies', I always pinch my nose to do Stevie's bit.
― The Roger Waters Experience (Turrican), Friday, 31 March 2017 01:55 (three years ago) link
nine months pass...
i got the reissue not that long ago so i've been listening to it a lot. it's funny to read the diverse reactions to welcome to the room....sara over the years. i didn't know it at all but it grabbed me right away--it's awkward and weird and tossed off but it has *something,* maybe in the big open chorus vocal and the way the backing vox come in, that i really like.
other big takeaway was john mcvie's playing on "little lies," a song i knew well but had never really dug into. i might think it's his best work in classic mac, which is saying something. he's the driving force in that song.
― call all destroyer, Wednesday, 17 January 2018 02:57 (three years ago) link
it's a perfect Christine McVie song too
― morning wood truancy (Alfred, Lord Sotosyn), Wednesday, 17 January 2018 15:03 (three years ago) link
I think "Everywhere" is more perfect, but "Little Lies" is more ... mysterious?
― Josh in Chicago, Wednesday, 17 January 2018 16:01 (three years ago) link
one month passes...
Sad seven wonders got no votes but this is a hard poll. Probably everywhere
― kolakube (Ross), Wednesday, 7 March 2018 21:44 (two years ago) link
T-ANN-GOOOOOOOOOOOOOOOOOOOOOOOOOOO
― morning wood truancy (Alfred, Lord Sotosyn), Wednesday, 7 March 2018 21:47 (two years ago) link
Alfred, do you still feel Honey, Hi is a dud??
― kolakube (Ross), Thursday, 8 March 2018 03:21 (two years ago) link
Yes -- an innocuous one.
― morning wood truancy (Alfred, Lord Sotosyn), Thursday, 8 March 2018 03:21 (two years ago) link
Alternative Tango coming for RSD
― papa don't take no meth (stevie), Thursday, 8 March 2018 10:33 (two years ago) link
Stevie's interjections in the "Little Lies" extended remix are A+
― morning wood truancy (Alfred, Lord Sotosyn), Thursday, 2 August 2018 01:43 (two years ago) link
This seems as a good as a place as any to air my suspicions (maybe this is common knowledge?) that the Lindsey-sung tracks on Tango (and Tusk) are pretty much all Lindsey, playing or programming everything, with a few exceptions and cameos.
― Josh in Chicago, Thursday, 2 August 2018 02:06 (two years ago) link
I assumed so from the beginning, "Caroline" and the title track in particular.
not so much on Tusk.
Pretty sure "Big Love" is just him, too. And "Family Man." Basically anything featuring his pitch-altered/sampled vocals. With "Tusk" it's a little more obvious which tracks are just him banging around in the bathroom. Though of course stuff like the title track and "What Makes You Think You're the One" and "Walk a Thin Line" feature at least Mick banging away as well.
I saw something about having Mick replace the drums on "Big Love" with a copycat performance.
― Ubering With The King (C. Grisso/McCain), Thursday, 2 August 2018 03:21 (two years ago) link
didn't he have Mick and John rerecord all the drum and bass tracks?
― niels, Thursday, 2 August 2018 06:15 (two years ago) link
He might have. Mick and John pop up on his solo albums as well. There are so many drum overdubs on "Big Love," specifically - those kind of marching fills at the end, cymbal washes, little fills - that it makes sense some of that is Mick (who iirc at the time of "Tango" was totally zonked out and living in a trailer in Lindsey's yard). Most of it sounds like programming or something Lindsey could do, but Mick can be such a smooth drummer maybe it is him. Not even sure I've ever even noticed a bass on "Big Love!" Or keys. Has the band ever played it live as a band?
There are definitely a few complete Lindsey solo tracks that got ported over directly to "Say You Will" with either Mick and John on the original track or sort of dubbed on later.
They do 'Big Love' all the time but as Lindsey's Acoustic Moment.
But never as a full band, right?
Playing Big Love as a full band would just obfuscate the insane skill level required to play that guitar part and then manage to sing on top of it.
The version on Tango In The Night was such a missed opportunity. If he had recorded it in the mode of "Never Going Back Again", it would have been a classic. But it was 1987, not 1977, so instead we got the porn backing vocals and the miami vice production.
― enochroot, Thursday, 2 August 2018 14:56 (two years ago) link
the og big love is great, how can you float "miami vice production" as a criticism and listen to the rest of the album
― princess of hell (BradNelson), Thursday, 2 August 2018 14:58 (two years ago) link
i'd like to suggest instead that it's lindsey's horny version of "running up that hill"
fair point, i suppose i do have the same issue with the rest of the album.
big love just feels different because of the missed opportunity. i remember when that song came out, and I just didn't connect with it all -- the "ugh/ahh" part at the end was really the defining element of the song. then several decades later, i heard a version of lindsay performing it solo, and it was stunning. i really couldn't believe it was the same song. or rather couldn't believe that the song he was playing was buried somewhere in the album version.
"running up that hill" is already v v horny
― 21st savagery fox (m bison), Thursday, 2 August 2018 16:21 (two years ago) link
but "big love" is def kate bushy and why i think it is dope af
can we ban "Miami Vice production" as criticism and phrase?
― princess of hell (BradNelson),
I'd long thought "Caroline" was but otm
my god
https://www.youtube.com/watch?v=tK3M6lBHA00
― morning wood truancy (Alfred, Lord Sotosyn), Thursday, August 2, 2018 12:43 PM (twelve minutes ago) Bookmark Flag Post Permalink
no, if anything it should be projected on the walls of every recording studio as a deterrent
― aloha darkness my old friend (katherine), Thursday, 2 August 2018 16:58 (two years ago) link
feel free to substitute "VHS cover meme"
alfred, thanks for the tip on little lies extended mix - have to hear that
― sleepy sweet (Ross), Thursday, 2 August 2018 17:04 (two years ago) link
The term "Miami Vice production" as a catch-all name for mid-to-late '80s production trends is useless, anyway.
― Le Baton Rose (Turrican), Thursday, 2 August 2018 17:06 (two years ago) link
Miami Vice used Bryan Ferry and Andy Taylor in its soundtracks: two distinct hair visions for the eighties.
I mean sure, you can tell that Tango in the Night, No Jacket Required, Born in the U.S.A. and Songs from the Big Chair all came out in the same decade, but the productions are still different from one another.
Also, I can't believe we're in 2018 and we're still seeing '80s records being criticised for sounding like records that were made in the '80s.
I was thinking more of modern-day records that strive to sound dated
Yet it's perfectly acceptable for Guided by Voices to record on 4-tracks and The White Stripes to record on old analogue equipment?
"Dated" isn't a pejorative, btw.
it is a sound I find highly unpleasant to listen to, how's that
That's better!
Framing "Big Love" as a missed opportunity presupposes that the live version had some notional existence at the time the original was composed - is there any evidence of that? I agree that Buckingham's live version is spellbinding, when I saw them live a few years ago it was the one moment of the show that gave me a chill even though I knew what was coming. But I've always assumed it was something that Buckingham developed after the fact. I'm just happy both versions of the song exist.
― Tim F, Thursday, 2 August 2018 20:10 (two years ago) link
I don't think the studio version of 'Big Love' was a missed opportunity at all. The live version is indeed great, but the studio version still holds up.
Obviously the other thing about Tango is that it's a front to back production masterpiece that feels totally one of a kind and cohesive* so the idea of wanting to swap out some of its rococo excesses and make it less "Miami Vice" feels like a violence to me. If ever there was a record where "sounding like Miami Vice" was elevated to the level of vital ontology it was this one.
*except where Stevie's songs fall over.
in time this has become my favourite mac record
― eris (Ross), Thursday, 2 August 2018 20:19 (two years ago) link
er next time to mirage
Another issue that I have with this whole "sounding like Miami Vice" bullshit is that Tango in the Night doesn't sound like Miami Vice at all.
Tim F OTM about the quality of the production on this record, though - although I don't think the production is overstuffed or even excessive. I can think of far, far, far worse examples of heavy handed '80s production.
Seriously, this isn't even that "80s."
Are there even snares that go "poosh?"
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Social Media (SoMe)
Profile of a Management...
International Training Day
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IMA webinars 2021
Offers for members
PAST WEBINARS AND VIRTUAL CONFERENCE 2020
IMA WITH YOU
Online conference 2020 - How to stay relevant for business?
Cybersecurity for Digitally Dependent IMA Members
by Shelagh Donnelly
Cybersecurity is a critical issue at the best of times, and it’s all the more important given the COVID-19 pandemic. IMA members and their employers have become increasingly dependent on digital communications as 2020 progresses. The World Economic Forum is one of many bodies to have recognised the significant increase in cyber risks all of us face given transformations to how we do business.
Whether you’re working remotely, in the office, or embarking on a hybrid arrangement, you’re likely relying on a combination of employer and personal hardware and servers. We’ll take a look at the potential implications a cyber breach can have for individuals and employers, and the tactics cyber criminals employ.
While the risks are real, there are practices you can adopt to mitigate both personal and professional risks. You’ll come away from this time with Shelagh with some simple, proactive measures you can take to reduce your cyber vulnerabilities. Join Shelagh in this session, and you’ll see why she’s called the cybersecurity whisperer.
The implications of a cyber breach
Recognizing risk
Mitigating risk: best practices
Canadian Shelagh (pronounced “Sheila”) Donnelly educates and coaches people who are focused on career fulfillment. After three decades in the career, and drawing on formal education in adult learning, Shelagh began speaking and writing full time in 2019. In addition to her Exceptional EA website, which she founded in 2013, she writes about governance and business for a major corporation. Shelagh speaks at conferences and delivers onsite training for government, higher education, governance and business audiences, including a stock exchange and corporations such as the NBA.
A recognised thought leader, Shelagh also invests time and care in staying attuned to developments in cybersecurity, governance, and the business world. She knows that what happens in these spheres will impact your career.
Given post-pandemic changes and challenges ahead, it’s wise to invest in learning from someone who thrived in your career though not only good economic times, but also during times of turmoil and recession. Shelagh has done just that. She was working alongside a COO at the age of 21. She’s been through a corporate merger, economic recessions, and the dissolution of one institution in order for two new ones to emerge. She left the career entirely while her children were little, then started again at the bottom of the org chart. She’s been a direct report to four CEOs and accountable to board Chairs, and worked alongside private and public sector C-level executives for most of her career.
Long active in Canadian and US professional associations, Shelagh’s been a mentor, led multiple initiatives, and served as the Chair of a national board of directors. Positive by nature, Shelagh is someone you can trust to speak realistically, yet with a healthy sense of humour. She’s someone to whom you can entrust the job of challenging and encouraging you as you make your way forward in your career.
For testimonials and abstracts of Shelagh’s image- and content-rich training sessions focused on how to navigate and succeed during pandexit times, see https://exceptionalea.com/for-event-planners/.
Email: ExceptionalEAs@gmail.com
Website: https://exceptionalea.com/
Twitter: https://twitter.com/ExceptionalEA
LinkedIn: https://www.linkedin.com/in/shelagh-donnelly/
Facebook: https://www.facebook.com/ExceptionalEAs/
Instagram: https://www.instagram.com/exceptional_ea/
ANGELA MORTIMER
What did you do in the Covid-19 Pandemic?
Key learnings will be:
- Mental health in the new Covid world.
- Learning to love what we have.
- Preparation for the new world of work.
Bio Angela
Angela Mortimer is the Founder and Director of one of Europe’s most successful recruitment consultancies, Angela Mortimer Plc. Established in 1976, her company currently employs approximately 150 staff in offices across London, New York, Brussels, Paris and Sao Paulo. The company has developed the careers of more than 300,000 individuals, mainly female, since its foundation.
Angela believes passionately in the need to encourage everyone especially women, to achieve their maximum potential. She seeks to inspire confidence and positive thinking by sharing insights developed over 40 years through training, public speaking and her blogs.
In 1995, in recognition of her company’s outstanding contribution to business life, Angela was made a Freeman of the City of London and is a member of the Worshipful Company of Fletchers. Angela is an International Speaker, delivering lectures helping women understand social and employment trends in order to achieve personal objectives. In 1996, she joined the Council of International Management Assistants, IMA (formerly known as EUMA) where she serves on the Affiliate Council advising on employment matters. Angela was a visiting lecturer on the Mountbatten programme in New York for over 20 years supporting graduates in finding placements after their Internship. Angela has made numerous appearances on television, including The British at Work on BBC2, Women in the Workplace, which was aired on television and radio, and produced a short documentary in collaboration with the Telegraph Business Club, highlighting the unique nature of the company she owns and in 2003, Angela was awarded the European Women of Achievement Award.
Angela is a patron and founder sponsor of the National Youth Ballet with an involvement motivated by the desire to foster the themes of women, youth and excellence. For several years Angela worked with the International Centre for Prison Studies counselling prison governors.
For over 12 years Angela served on both the Confederation of British Industries SME Council and The London Council of the Confederation of British Industry. In 2009 Angela was the winner of The First Women Awards for Business Services in association with Lloyds TSB Corporate Markets and supported by the CBI, and, in July 2003, Angela won the European Women of Achievement Awards in the Entrepreneur section. More recently, Angela was recognised by the Staffing Industry Analysts as one of the top 50 in their Global Power 100 – Women in Staffing list 2018.
JUANITA MORT
How to Manage your Manager in a digital world!
The focus of this program is to learn how to manage your boss and will look at tried and true methods admins have used for years, new methods that have come into play as technology became more widely used and how to find the correct balance for your working relationship. Attendees will discuss how technology has and continues to change the way admins work, the importance of building and maintaining a sound working relationship with your manager, and how the importance of staying current with trends and technologies allows them to be a better resource/working partner with their manager.
- Identify/understand your manager's style
- Identify what you can control (and what you can't)
- Identify tasks you can take on that will provide your manager with time to focus on higher level projects
- Build your working relationship/learn to be resource to your manager
- Improve your communication skills
Bio Juanita
Juanita Mort, CAP, OM, PM, MOSM is the Executive Assistant and strategic business partner to the Vice President, Information Services and Technology/CIO at HACC, Central Pennsylvania’s Community College. This role supports the learning experiences of the students by enriching their education through technology. She is also an adjunct faculty member on the Adult Education|Workforce Development team and provides small setting learning opportunities in the Microsoft Office platform.
With over 25 years of experience as an executive assistant supporting senior executives and CEO’s, Juanita has built a record of accomplishments through strong performance in high volume, high pressure environments. She skillfully manages administrative duties and is a staff trainer and mentor to new executive assistants.
Education and continued professional development are important components of Juanita’s personal growth/career plan. She holds associates degrees in Business Administration and Computer Information Systems. She also holds several industry certifications: IAAP Certified Administrative Professional (CAP) with specialty designations in Organizational Management and Project Management, Microsoft Office Specialist (2010, 2013) and Microsoft Office 2016 Specialist Master. Advocacy for the administrative profession is one of Juanita’s great passions. Juanita’s core belief is that admins and the vital roles they play in the success of their companies should be understood, recognized, and appreciated. Their voices should be heard and regarded as valuable. Passion drives success and success drives passion. Through her membership in the International Association of Administrative Professionals (IAAP), she has grown her network and enhanced her leadership skills through leadership roles at the local, regional, and international levels of the association. She is the current chair of the IAAP Board of Directors. Juanita is active in her community and currently volunteers her time with HACC-related opportunities on the Administrative Office Management Advisory Board and the President’s Next Generation Task Force. She also serves on the Finance Committee and community project “The Church has Left the Building” with her local church.
Juanita lives in Harrisburg, Pennsylvania, USA with her husband, Jerry. Between them, they have four children, eight grandchildren and three great-grandchildren and enjoying the fun of being Mimi and Pop-Pop.
SELVAGGIA FAGIOLI
& MICHELA LUONI
How to whip your boss into shape from home
What we know up to now about coronavirus is that it had forced us to invest time and effort into redesigning a new work experience. In the webinar we tackle these points:
Starting from a joint Working from Home bunch of problems, we will provide you with a practical checklist to create a new routine, with the help of our Trello Kanban board for remote team activities.
At the end of our webinar you should be able to:
1. develop strategies to identify and reduce the hidden time stealers working from home
2. explore the psychological factors affecting remote e-worker's well-being and work-life balance
3. create a new working routine to manage remote work effectively.
Bio Michela
VIRTUAL OFFICE MANAGER
I have 10+ years of experience as Manager Assistant in different company realities, and I blend all the skills acquired so far in my business: Daily Facilitator Virtual Office Manager, Training and Web Marketing services.
Training is an essential part of my business. In recent years I have developed various workshops on Personal Branding and LinkedIn strategies, as well as Digital Education; I worked on distance learning and mentoring for Executive Assistant, and I participated as a speaker also in international contexts.
I am a member and part of the Academy of IMA (International Management Assistants), former NPRO IMA Italy for two terms. At present, I'm the deputy head of Women Network Leader for my region.
Bio Selvaggia
START UP MENTOR
I am a Strategy Mentor with 15+ years of experience as Executive Assistant & Business Partner. My mission is to support managers to achieve their goals within the team, with the help of a training and mentoring path. I am passionate about start-up and innovation but also about improving business processes and information-flow. I have an Executive MBA from MIP-Politecnico di Milano. I am on the Italian Board of IMA Italy as National Treasurer and President of the Umbria Business Group Association, which aims to create business through networking.
GABRIELLA PICCA
Personal Branding and LinkedIn Profile
Today, more than ever, it is necessary to know how to move on the web. This is a historical moment in which all our ways of communicating and getting in touch with others are moving on internet, that is why our digital presence becomes fundamental to present ourselves at our best. We have to become owners of our digital footprint and decide how we want to be perceived. Carla Harris says ‘perception is the co-pilot of reality’.
Bio Gabriella
Gabriella Picca is an event manager for Linkedin Italy and Linkedin Iberia (Spain and Portugal). She is official Brand Ambassador of Linkedin and Manager Assistant for Linkedin Italy and Linkedin Iberia. As LinkedIn Brand Ambassador she carries out training sessions and workshops (live and online) mainly addressed to universities and schools, associations, companies and users. She is firmly convinced that Linkedin is today more than ever the social platform essential for personal development and professional path.
Gabriella has also being recently nominated by Capital Magazine as one of the top 50 assistants in Italy.
LAURA BELGRADO
Demonstrate your worth!
Our Role our Profession as Assistants was already changing rapidly and now we are in Wharp speed to so many changes both at work, professionally as well as in our personal lives. The EA/PAs of today need to demonstrate their worth, and this does not mean long hours of work, bringing coffee or just being nice. We need to take the next step forward, today, rather than tomorrow. It is about managing crisis as we experience today, resilience, forward thinking, pro-active and definitely about learning to communicate effectively and with assertive and positive attitude and mindset. I want to bring you some ideas, motivation and personal experience as well as input from my own Executive. Together we can do this!
Bio Laura
Laura Belgrado has over 30 years of experience working in an International Corporate environment; 10 years as Executive Assistant to the Global Managing Director of Microsoft Global Strategic Accounts. She continued her career as EA working for the President and 2 VP’s at MARS Inc. for the Mars MultiSales markets and was promoted 2 years ago to Project Coordinator and EA to the President KIND International for MARS. Inc. Laura now is also part of the Leadership team alongside her Manager to lead and support the LT into the Global launch of a new Healthier snack segment at MARS Inc.
She has travelled around the globe coaching Executive & Personal Assistants. She is a licensed Executive Coach (AoEC and ICF Certified). She has long and vast experiences working with top global CEOs as their trusted EA and advisor.
In the past 12 years, Laura has been designing and delivering training and coaching programs for Executive Assistants, Personal and Administrative Assistants. Her experience in Event and Project Management for over 18 years is now proving to be a great asset and a much needed experience and knowledge to take part in the ‘Crisis Team’ Video calls with her Executive and LT as well as reaching out the Assistants communities around the globe to give guidance and tips on how to manage the current COVID-19 situation as well as some great tips on ‘Working from Home’ and Communication with your Executive(s).
SOFIE KOARK
Management Assistants - taking action for our planet!
Sofie Koark shared her thoughts about sustainability related to our role in this webinar.
Climate change due to global warming is an urgent & devastating threat. As an individual, you can feel powerless to stop this chain effect, but doing something is better than doing nothing.
How many Management Assistants are there in the world? What would happen if we all decided to work against climate change?
As Management Assistants, we are leaders and we are buyers. We can start to make conscious decisions in our daily choices in order to reduce the negative climate impact.
If all of us start to put climate change on the agenda, it will make a difference and inspire others. Let's be leaders, innovators and good role models for sustainability.
We are doers, solutions-oriented and through our global network we can share ideas and inspire each other to take good initiatives.
Sofie is Training Officer in IMA Sweden and a member of the Swedish board.
Laura Belgrado shared her experience not only how she works and manages her Executive remotely, but especially now during the current CV-19 crisis – how in our Profession and our Role it is key to ensure our own safety and well-being and that of our loved ones.
Some techniques on ‘behavior management’ in times or crisis and how to take a pro-active approach with your Executive.
Laura also feels that this current situation is a great opportunity for many Assistants out there. How can we be ready with a plan B and revisit our personal skills.
To close Laura will share some important do’s and don’ts for remote working.
Professional Master for Executive Assistants
Online Training Program - co created by IMA
– an online training program for taking the role to new levels.
Earn a tangible online degree
+20 exclusive video presentations featuring industry leaders such as Adam Fidler and Laura Belgrado
Based on online lectures, presentations, podcasts, reading materials, assessments, manually graded assignments and more
Online learning community: Discuss and collaborate with global colleagues
IMA members gets discount. Check our Members offer
Read more at execuni.org
Past Webinars 2019
MINA DHIFALI
Protect your time: Your diary is your BOSS, anticipate weekly, monthly and yearly
Mina Dhifali, 39 years old, French, born, raised and educated in Paris. She is a single mother of a 7 years old daughter, a passionate professional and a go-getter woman. Being raised in both French and African cultures has been a blessing for her. She started travelling at 7 months to Algeria for holidays, and she has never stopped since then, discovering new countries, new cultures and, connecting with people have always been a spiritual quest. She founded My French PA in September 2017, an agency of business support services. Her mission is to reinterpret the traditional corporate role of an executive assistant within the digital age: she is often considered as a strategic business support partner by her clients.
She proposed virtual and on-site several services for English speaking international businesses and individuals in Paris, as French bureaucracy, PA services, event management, to name a few.
Her main expertise is Time Management: a whole-solution approach to take care of the day-to-day in the professional life so that my clients may focus – clearly, cleanly – on their core business.
WINNER BEST OF PARIS 2018
Description Webinar: This was a presentation of a clear strategy with tools and process of how to protect your time in workplace.
HELEN MONUMENT
What to do when the sky falls
Life is what happens to you while you’re busy making other plans. So just imagine: you have a path mapped out for yourself, you’re happily on your way and then something happens that stops your life in its tracks. It could be a huge, life-changing event, losing your job, being the victim of a crime or the day to day events in the office that take a different turn that you just didn’t see coming. Whatever it is, it’s unexpected, it’s unwelcome and it’s upsetting. So what do you do?
In this webinar, Helen shared her experiences, tips and techniques about what you can do when the sky falls.
Helen is a former Executive Chairman and Association Secretary of EUMA (now IMA) and after more than 30 years experience as a Secretary, Management Assistant, PA and Team Leader, she has founded Monumental Assistance: training, mentoring, coaching, writing and speaking at conferences for Assistants all over the world. She’s passionate about our profession and believes that we all have an obligation to ‘pay it forward’ by encouraging Assistants at all levels to continuously improve and never stop learning.
KAREN NANNINGA
Coaching skills for Assistants – A constructive approach for your interaction and communication
Assistants, by the nature of their roles, hold interface positions. They are like the spider in the centre of their webs, pulling all the strings in terms of coordination and communication, overseeing all that is going on. Also by the nature of their jobs, they have little hierarchical power. AND … from the centre of the web they can exert a lot of influence … and that’s maybe even more powerful than power.
Exerting influence for the sake of creating win-win situations is “servant leadership”. To serve is also the basis of a coaching relationship.
In this webinar we will explore the coaching approach for your communication and interaction. You will learn that this is much more than a few techniques. A coaching approach means that you are willing to take responsibility for your mindset and to act from intention. You will acquire some easy to apply skills. We will do a number of exercises and … come prepared to commit to a homework assignment, like in a real-life personal coaching session.
The webinar will be led by Karen Nanninga, experienced Trainer and Certified Coach (CPCC, PMC). She was National Chairman of EUMA Netherlands and Executive Chairmen of EUMA, now IMA. Karen strongly believes that each individual can make a difference in his/her own environment, no matter what position (s)he holds. Each person’s role goes beyond his/her job description, as we all bring unique personal competence, talents and interests to the workplace. Leadership is her motivation and message in all her professional areas and activities.
LUCY BRAZIER
So You Think You're a Strategic Business Partner - But What Does that Mean? By Lucy Brazier, CEO of Marcham Publishing
Much has been made in recent times of the emergence of the assistant as a strategic business partner.
Indeed, Google has just changed the name of its top Assistants to Administrative Business Partner.
The term is THE buzzword in the industry right now. But how do you become strategic? What does it mean? How to you change your day to day role to become the assistant that your executive needs as Executive Support in order to deliver at the highest levels.
We looked at why businesses still need assistants but why the landscape has changed, how to develop your business acumen to best support your manager and what skills are required to be a true strategic business partner to your boss.
ADAM FIDLER
The Executive Assistant Manifesto™ – What it means and why it should matter to every EA
A special webinar recorded exclusively for IMA by the UK’s leading provider of training and education for EAs, Adam Fidler of Adam Fidler Academy
In this webinar, Adam, a former corporate EA of 20 years, covered:
• The story behind the Manifesto, why and how it was written.
• How to articulate the true Executive Assistant role.
• How Assistants can use the Manifesto to set stretching goals and develop new capabilities to future-proof their roles.
• Why Executives also love the Manifesto, and what it means to them (the bosses).
• How Assistants can build better-buy in from their Executives using the Manifesto.
• Key considerations, and challenges, for the future of the EA role in light of global trends, competency frameworks, innovation and change.
LAUREN BRADLEY
The influential assistant
Lauren has over 10 years experience as an admin across the globe. Having worked in the USA, UK and as a virtual admin for companies in Australia and Thailand. In 2016, she was named one of OfficeNinjas‘ All-Stars, an award given to top performing admins. She is passionate about connecting fellow admins and in 2015 she founded The Officials to empower admins through community, courses and coaching. She is a working admin, networker, brand ambassador and public speaker. She currently lives in London, UK where you can find her constantly neglecting her cup of tea and operating on shockingly little sleep while juggling career and family (2 adorable daughters!)
To learn more visit: https://jointheofficials.com/
MICHELA LUONI
Brand Reputation + LinkedIn - how to create a star profile
LinkedIn Connect to Opportunity: choose yours
If you ever thought "I have a profile on Linkedin, but I don't know what to do with it" then this introduction to the first professional social network is for you.
Your reasoning is correct: having it and not using won't bring you clients, nor will land you a job. Hence, what are the "hidden secrets" of successful people who use it properly? A premium version? Nope! They use it with a strategy and an intention.
In this hour we manage to learn: How does it (really) work and why you have to use it, as a professional. Five necessary key points to start with and lead to an A-star Profile
Presented by Michela Luoni, Virtual Office Manager, who founded her own brand company, www.dailyfacilitator.it, in 2017 and started the challenging process of being a solopreneur after having spent her whole life as an employee.
Michela firmly believes that networking is crucial for every MA and professional, whichever will be the path your career will take.
“Being part of two professional networks helped her a lot in the transition from EA to entrepreneur”. Michela has been an active IMA member since 2014, where she served as a PR Officer in IMA Italy.
SUE FRANCE
Maximise your brain for excellence!
Sue taught us how to: - Use neuroscience tips to build and maintain confidence - Understand and maximize your brain’s potential - Apply a tool for overcoming the “fear” factor - Tips, tools, and techniques for boosting your brainpower
Bio Sue:
Sue is a certified Neuro Linguistic Programming practitioner, qualified learning and development practitioner, a Fellow of the Chartered Institute of Personnel & Development, A Fellow of the Institute of Administrative Management, an experienced and award winning assistant and internationally renowned coach and trainer. Sue is a neuroscience enthusiast and combines it with Neuro Linguistic Programming to give a powerful and empowering presentation. Sue is the author of the award winning “The Definitive Executive Assistant & Managerial Handbook” and “The Definitive Personal Assistant & Secretarial Handbook.” Sue is offering a discount of 20% off each book when you purchase from www.suefrance.com by putting the word FAVOUR in the code box and she will personally sign the books for you. You can also contact Sue by email sue@suefrance.com if you have any queries.
DIANA BRANDL
Working with millennials - meet the new manager generation of the digital age
Diana shared her advice on how to tackle millennial executives who are becoming more and more common as the new manager generation in the digital age. She has been working with them for almost two years and will introduce this new "species" of micro-managers, digital natives and 24/7 executives to us by describing their management and leadership style. You well learn a lot about your own strengths and many opportunities that come with the new manager generation for our profession.
Bio Diana:
Diana Brandl holds a Degree in International Administration and Management, specializing in Office Management. Throughout her career, she has worked successfully for C-Level Executives within global corporations such as Sony, ratiopharm and Mister Spex. Diana has a strong background in Communications and is an active networker. She joined IMA in 2006, and is a Member of the Board serving as Acting-Public Relations Officer for IMA Germany and is also chairing the Regional Group of IMA Berlin / Germany. She continuously supports the role of the management assistant by speaking at international events and publishing various articles in Germany and abroad. Diana writes her own blog The Socialista Projects and is influencing the industry with her creative initiatives such as launching the hashtag #WeAreInThisTogether
Cyber security for digitally dependent IMA members
The implications of a cyber breach Recognizing risk Mitigating risk: best practices
Copyright © 2021 IMA - International Management Assistants - All rights reserved
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Home › Latest Articles › News Updates › More Expensive Airfare For Malaysians Soon?
More Expensive Airfare For Malaysians Soon?
News Updates, Travel
Written by Fiona Ho
Airlines operating out of Malaysia are expected to pay up to ten times more in fees charged by the Department of Civil Aviation Malaysia (DCA) starting from April 15.
The spike in fees will apply to everything from the usage of air space, air traffic facilities, pilot’s flight license, and other services to the air operator’s certificate (AOC).
Most saliently, it will lead up to a ten-fold increase in a monthly air navigation flight charges (ANFC), which forms the biggest cost item for the usage of DCA services.
With the revised fees, bigger aircrafts will bear the biggest financial brunt, but smaller jets, cargo planes and helicopters are not spared either.
The biggest fear for consumers is that the fee increases could potentially lead to higher airfares. Airlines may also impose miscellaneous charges in a bid to pass on the higher cost to consumers.
According to The Star, the ANFC charges will rise from five sen per nautical mile now to 50 sen for lightweight aircraft.
For the bigger birds (the A320/A330 and B737/B777), the cost will rise from RM1 to RM2.50 per nautical mile instead of 10 to 25 sen now, and the super jumbo A380 will see charges go up to RM3 from 30 sen now. The minimum charges will be raised from RM5 to RM50 per nautical mile.
As for the AOC, a vital document for airlines to fly, the initial approval fees will balloon to RM80,000 yearly from RM400 now for mid-sized aircraft, and yearly renewals will rise from RM400 to RM30,000.
Further, pilots who have to be licensed to fly will have to fork out RM500 for their initial flight crew licence and RM300 for yearly renewals from RM100 and RM60 now.
With the increase, if an airline is currently paying RM120,000 a month in ANFC fees, its bill will rise to RM1.2 million a month after the increment depending on aircraft type and frequency.
For example, flights to East Malaysia, a high-frequency route, will cost airlines more from a mere RM160 to RM176 for 800 nautical miles to RM1,600 to RM1,760 for the KL-to-Kota Kinabalu route when the new charges come into effect, although it depends on aircraft type and frequency, The Star reports.
The DCA director-general Datuk Seri Azharuddin Abdul Rahman said that while some airlines are unhappy with the new charges, they have to understand the expenses for delivery is going up.
“We have to upgrade our systems, maintain and replace them as we want to give them the best. Hence, we have to charge a bit. In any case, there has not been a revision in the pricing since 1970 and it costs us money to provide the services,” he told The Star.
He added: “If you look at the statistics, we are still the lowest in the world, and even if we increase the fees, it will still be lower compared to some other countries in this region.”
He said the DCA had spent RM1.41 billion to build infrastructure and systems to deliver an efficient air traffic management system. The new KL air traffic control centre (ATCC), expected to be operational by 2018/2019, is costing the DCA RM650 milllion, he said.
For future upgrades, the DCA needs about RM550 million to upgrade the new Kota Kinabalu ATCC and for other system upgrades elsewhere in the country.
“Yearly, we are spending about RM125 million just on maintenance, and that is why we need to raise our rates. We are essentially building a new ATCC for the benefit of the airlines,” Datuk Seri Azharuddin said.
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What if the rumored iOS 8 Healthbook wasn't just for an iWatch but for an internet of health things?
One of the most persistent rumors for iOS 8 focuses on Healthbook, a Passbook-style, card-based "wallet" app that would collect all your fitness, nutrition, sleep, and medical data all in one place. These rumors have been tied to the iWatch as a way Apple could track more and better health-based information, but there's also been speculation that Apple might go broader. Benedict Evans:
Suppose, for the sake of argument, that Apple does indeed plan a health app that's card-based, somewhat like Passbook. What would happen when you buy and turn on a blood pressure monitor that is certified for 'Healthbook'? Well, one would expect that Apple would use the Bluetooth LE auto discovery that's already in iOS7 to detect it automatically and tell you. And then, suppose it offers to install the Healthbook card to manage it (either from iTunes or from the device itself) - an HTML/Javascript package that runs in the Healthbook sandbox in some way. Suppose it does the same for any sensor you might buy? Then Apple has created a zero-setup platform for personal health devices. No apps, no native code, no app store, no configuration at all.
This would be one answer to why Apple's recent hires of 'wearables experts' sound a bit like a team for a hospital device rather than a watch, measuring various quite technical things - because Apple plans to enable such devices, not try to pack every single one into its own device. That is, the straightforward sensors should live in the phone (like the pedometer that's already in the iPhone 5S) and the complex and demanding ones should be enabled by an Apple platform, not become part of an Apple device.
Evans goes far beyond this, wondering out loud if this new, decoupled model could extend to Apple TV, CarPlay, and products from Google as well. In essence, whether apps and the web as we know it could be morphing into something more dynamic and more on-demand.
I've been hoping push-interface would emerge for a couple of years now. Check out Evans' piece and let me know — how would you want to see Healthbook and other next-generation services work?
⌚️ 🍎 🙌🏼
Don't spend a fortune on the Milanese loop—get the look for less!
Getting that Milanese loop style doesn’t have to cost you a small fortune — here are a few great alternatives that won't break the bank!
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Home » Business » Exclusive: U.S. authorities probe alleged forged letter from Mirach in Sahara deal
Exclusive: U.S. authorities probe alleged forged letter from Mirach in Sahara deal
Feb 19, 2015 264 Viewed Gautam Comments Off on Exclusive: U.S. authorities probe alleged forged letter from Mirach in Sahara deal
Federal authorities in San Francisco are probing U.S.-based Mirach Capital Group, two sources familiar with the situation told Reuters, amid allegations that the group gave a forged bank letter to Indian conglomerate Sahara as part of financing negotiations.
Sahara had sought to borrow more than $1 billion from Mirach to help bail its chairman, Subrata Roy, out of jail in New Delhi. Roy was jailed last year for contempt charges for failing to comply with a court order to repay investors in a bond transaction that was ruled to be illegal.
His bail was set at $1.6 billion, the highest ever in India, and his company sought to raise money to pay for it. The Indian conglomerate was willing to use hotels it owns, including New York’s Plaza, as collateral.
The company negotiated for funds with Mirach, a group set up by former broker Saransh Sharma, who lives in Northern California. Mirach gave a letter to Sahara that purported to prove the U.S. group had the funds in an account at Bank of America to lend to the Indian company, but after a Reuters report earlier this month raised questions about the authenticity of the document, Sahara said it was a forgery.
Sahara said it would initiate civil and criminal legal action against Mirach in India and the United States.
One source said the Federal Bureau of Investigation’s office in San Francisco is currently investigating Sharma, and another said the probe involved the Sahara allegations of a bank letter forgery. FBI spokesman Gregory Wuthrich in San Francisco said he could not confirm or deny an investigation.
A lawyer for Sharma said that Sharma has not been contacted by the FBI, and demanded that Reuters refrain from publishing a story. “We have no reason to believe that your source is anything more than a mere propagandist for some group that is adverse to Mr. Sharma and/or Mirach,” Sharma’s lawyer wrote.
A Bank of America representative declined to comment on the investigation.
Roy’s bail reflects the scale of the illegal bond transactions. The court has said investors need to be repaid as much as $7 billion including accrued interest.
Filed in Business
CBI files final report in coal block case
SpiceJet’s new ‘one stop sale’: Now, tickets up for grabs at Rs 2,999
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Elon Musk Reveals Details of Tesla V9.0 Software, Including Early Access
Oscar Gonzalez
A new version of Tesla’s Autopilot is a month away. CEO Elon Musk made the announcement via Twitter on Wednesday of the upcoming v9.0 update. He tweeted extra details about the upgrade on Sunday including info about getting early access to the new version.
When Musk responded to one Model 3 owner’s praise for the electric car on Twitter and mentioned the upcoming Autopilot upgrade, another person asked the CEO about the changes v9.0 would have on Model S and X vehicles. Musk said it will include video games and other changes, and the update will be available for vehicles made in recent years that have the correct Autopilot Hardware.
“Games & other refinements will go to all Tesla S, X & 3 from start of production,” Musk tweeted. “Autopilot enhancements apply to all Model 3’s plus S & X made in last few years (needs Autopilot Hardware V2.0 or higher).”
Another Twitter user asked if there would be early access to v9.0 upgrade. Musk tweeted that early access would have bugs and was not advisable since there would have to be a plan for something to go wrong. Musk said back in June the v9.0 would be the release to include the full self-driving features to make Teslas autonomous.
Prior to the Tesla earnings call on Wednesday, Musk put out a call for game developers to come work for Tesla. He tweeted in the past about the possibility of having the option to play video games with the Tesla touchscreen control panel.
During Wednesday’s earnings call, Tesla once against lost money in the quarter to the tune of $740 million. However, there was growth in the company’s numbers and Musk said it finished its last unprofitable quarter, which caused the stock to rise significantly in the following days.
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Combining Vitamin E with Selenium kills prostate cancer cells
Researchers at the University of Wisconsin have just reported that a combination of vitamin C and E administered to human prostate cancer cell cultures kills the prostate cancer cells. The finding adds support to the hypothesis that vitamin E and selenium are of value in prostate cancer prevention, which is being investigated by the twelve-year Selenium and Vitamin E Chemoprevention Trial (SELECT) that includes over 32,000 healthy men. Adding Vitamin E Succinate or Selenium alone modestly inhibited the growth and viability of the prostate cancer cells, adding the combination of the two dramatically inhibited prostate cancer cell growth while having no effect on either growth or viability of normal cells.
Chromium picolinate reduces hunger and weight in overweight women
Researchers from Louisiana State University, and the University of Florida recruited 42 overweight women. They gave them either Chromium Picolinate at a dosage of 1000 mcg daily or inactive placebo for 8-weeks. Those women on Chromium voluntarily consumed 25% fewer calories because they felt satiated.
Coenzyme Q10 and Fenofibrate help lower blood pressure in diabetics
Researchers at the School of Medicine and Pharmacology, University of Western Australia in Perth investigated the effects of the cholesterol lowering drug fenofibrate and Coenzyme Q10 (CoQ) on diastolic function, blood pressure (BP), and heart rate (HR) in type 2 diabetics with left ventricular diastolic dysfunction (LVDD). The scientists performed a randomized double-blinds study prescribing different combinations to 74 subjects; fenofibrate 160 mg daily, CoQ 200 mg daily, fenofibrate 160 mg plus CoQ 200 mg daily, or matching placebo for 6 months. Echocardiography (including tissue Doppler imaging) and 24-h BP and HR monitoring were performed pre- and post-intervention.
Low plasma Vitamin K1 is associated with high incidence of spinal fracture in Japanese women
Scientists at Kobe Pharmaceutical University in Japan note it has been reported that vitamin K supplementation effectively prevents fractures and maintains bone mineral density in people treated for osteoporosis. The objectives were to evaluate the association between plasma K1 or K2 as MK-4 and MK-7 concentration and bone health or fracture in Japanese women. A total of 379 healthy women aged 30-88 years (average age of 63) were consecutively enrolled.
Isoflavone supplementation improves blood flow in stroke patients
Isoflavones, a powerful group of nutrients found in soybeans, and to a lesser degree in chickpeas and other legumes, can improve artery function in stroke patients, a new clinical study has found. This is the first investigation into the effects of Isoflavone supplementation on the brachial artery, which is the main artery in the arm. The trial involved 50 patients taking the isoflavone supplement, and 52 on inactive placebo for comparisons sake.
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人们 PEOPLE
进行项目 PROJECTS
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Benandsebastian's 'Museum Of Nothing' at Black Sesame
Institute for Provocation presents an exhibition and presentation of the ongoing project 'The Museum Of Nothing' by resident artist duo benandsebastian. The Danish/British artist duo benandsebastian have been conducting research in Beijing for the Museum of Nothing in conversation with experts from several of the city’s museums. The artists came to China with a series of questions about the role of absence in institutions, such as: how do we fill in gaps within our material knowledge, how do we recreate what is lost, and how is the absent embedded in objects and artefacts that remain. The artists arrived in Beijing airport last August with two transport cases on loan from the Museum of Art and Design in Copenhagen. The transport cases shared the characteristic of having been made for specific artefacts that have since been lost from that museum’s collection, as have all traces of their identity and provenance. Now the only record of these absent artefacts is the cases that once carried them. As the artists journeyed between Beijing’s museums with the transport cases, the empty objects came to serve as vessels for questions about origin, authenticity, imitation and the relationship between original and copy. Rather than providing answers, the series of encounters with museum professionals, academics and local craftsmen in Beijing have repeatedly re-written the questions that the Museum of Nothing poses. Opening: January 25th, 4pm Black Sesame Space Heizhima hutong 13 Dongcheng district Beijing 10009 About the artists: Ben Clement and Sebastian de la Cour have been working together since 2006 as the British/Danish artist duo ‘benandsebastian’. They have exhibited internationally during that time in museums and institutions in New York, Copenhagen, London and Berlin. Benandsebastian are interested in how meaning is embedded in spaces and objects in conditions of absence. Their intricate and highly-crafted installations have inbuilt gaps and are often on the verge of collapse. Whether taking the form of architectural fragments, mechanical theaters or living artifacts, their works relate to the idea of a body that is incomplete and vying with its own phantoms. In their recent work they have pursued the potential of absence, gaps, incompletion and anomaly within the context of several museum collections, in a form of materialized institutional critique.
Institute for Provocation
4/F, Suit B7-3A, 706 North 1rd St.,
2 Jiuxianqiao Rd (798 art zone),
Chaoyang District,
Beijing,
激发研究所
北京市朝阳区酒仙桥路2号（798艺术区）706北一街B7-3A,4楼。
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CONCERT REVIEW: Where’d you go Tyler, the Creator?
Posted By Laura Johnson on Wed, Jul 1, 2015 at 12:58 PM
At Tuesday night's Tyler, the Creator show, the MC skipped out on an encore.
It could have been a combination of things: the heat, tiredness, perhaps he was hangry. Whatever the reasoning, Tyler, the Creator didn’t come out for an encore at last night’s Knitting Factory show to the disappointment of his fans.
No artist is required to do anything, and coming back out to do just one more song isn’t necessary. Maybe we shouldn’t expect it. But seriously? Besides festival shows where there isn’t the time, I can’t even think of the last time I didn’t see an encore for a big show. The rapper was only out on stage for a little over an hour, and last night he left his audience wanting more.
The neon-clothed kids (and these really were kids — there was a row of waiting parents in cars after the show let out) had already lined up outside well before 5 pm for a show that wouldn’t start until about 8:30 pm. Once inside, they packed in, excitedly waiting for a guy many parents would freak out over if they ever read his lyrics.
Taco — not to be confused with this Taco — warmed up the stage for his man Tyler, spinning a bunch of Jay-Z, Lil’ Wayne, Kanye and more. Then out of nowhere, the artist burst onto the stage as if blasted out of a canon going straight into the song “Bitch Suck Dick.” Ah, yes. Joined by Jasper Dolphin, a fellow Odd Future cohort, he glided quickly around the stage. Sometimes there was gangsta swagger, other times he looked like an adult man throwing a tantrum.
After that first song he moved into the part of the show where he spoke to the audience. He called out one dude for using a selfie stick, he pointed out one woman's outfit whose hair looked like big Minnie Mouse ears.
“Have I been to Spokane before?” he asks a cheering crowd. “I guess it
must have been a long time ago. What do you do around here? It looks like nothing.”
And with all of these sweet things to say, the MC moved into more crowd-pleasing songs like the slow “IFHY” (perhaps his answer to Eminem’s “Stan”), the money-motivated “Smuckers” and the pedophilia-vibing song “F—-ing Young / Perfect.” For everything he did, the audience fist-pumped and jumped and cursed him and sang along with nearly every word.
Right around 10 pm, he stripped off his white T-shirt, thanked the crowd and peaced out … never to return.
But even if Tyler wasn’t interested in being in Spokane any longer than he needed to, let it be known he worked his ass off with the songs he did do. There were breaks between tunes that lasted almost a minute just so he could catch his breath and towel off the gallons of sweat pouring out of him. He was scary, he was raw, he made all the faces. He was even kind enough not to incite a riot.
People had a lot of fun Tuesday night, and even with Tyler leaving straight to his hotel right after, that feeling of abandon while his catchy music was pumpin’ is what everyone will remember. And that’s what they should remember.
Tags: Tyler , the Creator , Concert review , Knitting Factory , Taco , Music , Image
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Downtown's latest mural, Get Lit! combines physical and digital, new music and more!
American Inheritance: Unpacking World War II @ Northwest Museum of Arts & Culture
Tuesdays-Sundays, 10 a.m.-5 p.m. Continues through May 23
Laura moved to the great Inland Pacific Northwest this summer. She is the Inlander's new music editor.
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Clinical MedicineCardiologyVascular biology Free access | 10.1172/JCI94601
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans
Robert A. Koeth,1,2,3 Betzabe Rachel Lam-Galvez,4 Jennifer Kirsop,1,2 Zeneng Wang,1,2 Bruce S. Levison,1 Xiaodong Gu,1,2 Matthew F. Copeland,4 David Bartlett,1 David B. Cody,4 Hong J. Dai,5 Miranda K. Culley,1 Xinmin S. Li,1,2 Xiaoming Fu,1,2 Yuping Wu,6 Lin Li,1,2 Joseph A. DiDonato,1,2 W.H. Wilson Tang,1,2,3 Jose Carlos Garcia-Garcia,4 and Stanley L. Hazen1,2,3
1Department of Cellular and Molecular Medicine, Lerner Research Institute,
2Center for Microbiome and Human Health, and
3Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
4Life Sciences TPT and
5Global Biosciences, The Procter & Gamble Company, Cincinnati, Ohio, USA.
6Department of Mathematics, Cleveland State University, Cleveland, Ohio, USA.
Address correspondence to: Stanley L. Hazen, Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, mail code NC-10, Cleveland, Ohio 44195, USA. Phone: 216.445.9763; Email: hazens@ccf.org.
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Published December 10, 2018 - More info
Published in Volume 129, Issue 1 on January 2, 2019
J Clin Invest. 2019;129(1):373–387. https://doi.org/10.1172/JCI94601.
Copyright © 2019, American Society for Clinical Investigation
Published December 10, 2018 - Version history
Received: July 28, 2017; Accepted: October 30, 2018
BACKGROUND.l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut microbiota–dependent formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) via a multistep pathway involving an atherogenic intermediate, γ-butyrobetaine (γBB). The contribution of γBB in gut microbiota–dependent l-carnitine metabolism in humans is unknown.
METHODS. Omnivores and vegans/vegetarians ingested deuterium-labeled l-carnitine (d3-l-carnitine) or γBB (d9-γBB), and both plasma metabolites and fecal polymicrobial transformations were examined at baseline, following oral antibiotics, or following chronic (≥2 months) l-carnitine supplementation. Human fecal commensals capable of performing each step of the l-carnitine→γBB→TMA transformation were identified.
RESULTS. Studies with oral d3-l-carnitine or d9-γBB before versus after antibiotic exposure revealed gut microbiota contribution to the initial 2 steps in a metaorganismal l-carnitine→γBB→TMA→TMAO pathway in subjects. Moreover, a striking increase in d3-TMAO generation was observed in omnivores over vegans/vegetarians (>20-fold; P = 0.001) following oral d3-l-carnitine ingestion, whereas fasting endogenous plasma l-carnitine and γBB levels were similar in vegans/vegetarians (n = 32) versus omnivores (n = 40). Fecal metabolic transformation studies, and oral isotope tracer studies before versus after chronic l-carnitine supplementation, revealed that omnivores and vegans/vegetarians alike rapidly converted carnitine to γBB, whereas the second gut microbial transformation, γBB→TMA, was diet inducible (l-carnitine, omnivorous). Extensive anaerobic subculturing of human feces identified no single commensal capable of l-carnitine→TMA transformation, multiple community members that converted l-carnitine to γBB, and only 1 Clostridiales bacterium, Emergencia timonensis, that converted γBB to TMA. In coculture, E. timonensis promoted the complete l-carnitine→TMA transformation.
CONCLUSION. In humans, dietary l-carnitine is converted into the atherosclerosis- and thrombosis-promoting metabolite TMAO via 2 sequential gut microbiota–dependent transformations: (a) initial rapid generation of the atherogenic intermediate γBB, followed by (b) transformation into TMA via low-abundance microbiota in omnivores, and to a markedly lower extent, in vegans/vegetarians. Gut microbiota γBB→TMA/TMAO transformation is induced by omnivorous dietary patterns and chronic l-carnitine exposure.
TRIAL REGISTRATION. ClinicalTrials.gov NCT01731236.
FUNDING. NIH and Office of Dietary Supplements grants HL103866, HL126827, and DK106000, and the Leducq Foundation.
Recent studies identify a mechanistic link between a Western diet, gut microbiota–dependent metabolism, and development of both cardiovascular disease (CVD) and metabolic diseases (1–3). For example, the ingestion of trimethylamine-containing (TMA-containing) dietary nutrients enriched in animal products such as choline, phosphatidylcholine, and l-carnitine can serve as precursor for the ultimate generation of an atherogenic metabolite, trimethylamine N-oxide (TMAO), via a metaorganismal pathway involving initial gut microbial formation of TMA, followed by host hepatic conversion of TMA into TMAO (4–8). Elevated plasma TMAO concentrations predict incident CVD risks in multiple clinical cohorts (4–7, 9–14), and both animal models with microbial transplantation (4, 15) and various studies on mice and humans with raised TMAO have revealed mechanistic and prognostic links between microbial TMAO production and both atherosclerosis and thrombosis, as well as chronic kidney disease and heart failure (4–6, 12, 13, 16–18). Importantly, recent studies aimed at blocking the metaorganismal TMAO pathway through multiple approaches have confirmed the inhibition of diet-dependent atherosclerosis in animal models, either by targeting the initial microbial formation of TMA from choline through use of a nonlethal small-molecule inhibitor (19), or by targeting the second step in the pathway, the major host gene responsible for converting microbe-generated TMA into TMAO, flavin monooxygenase 3 (20, 21). More recently, a family of potent and highly selective mechanism-based suicide substrate inhibitors were developed and shown to promote the irreversible inhibition of gut microbiota–dependent generation of TMA, suppression of host TMAO levels, and, in parallel, inhibition of platelet hyperresponsiveness and thrombosis potential in animal models (22). Moreover, microbial transplantation studies in germ-free mice with human commensals containing a functional (but not a deletion mutant) microbial cutC gene (responsible for choline→TMA transformation) (23) and genetic manipulation (both gain of function and loss of function) of host hepatic flavin monooxygenase 3 have been shown to modulate host TMAO levels, platelet responsiveness, and thrombosis potential in vivo (24). Thus, substantial and mounting evidence supports a direct contributory role of gut microbiota as a participant in CVD pathogenesis, and preclinical studies indicate that the therapeutic targeting of microbial contributors to the TMAO metaorganismal pathway may hold promise as a novel approach for the prevention or treatment of CVD. Accordingly, an improved understanding in humans of the microbial pathways involved in TMA/TMAO formation from distinct nutrients is an essential and necessary step in the development of targeted interventions to interrupt these processes.
l-Carnitine, a nutrient found primarily in red meat, was recently reported to be metabolized by gut microbiota to form TMA via the 2-component Rieske-type l-carnitine oxygenase CntA/B (25, 26), which requires molecular oxygen for activity. Although CntA/B may be responsible for some TMA formation by γ-proteobacteria intimately associated with the intestinal epithelium using oxygen that diffuses into the luminal content, because of its oxygen requirement, it is unlikely to be the primary physiologic source of l-carnitine→TMA activity in the mostly anoxic luminal intestinal environment. Furthermore, CntA/B-encoding genes have been identified only in facultative organisms and not in the many anaerobes that form the bulk of the gut microbiota (27). However, isotope tracer studies confirm that TMA and TMAO are sequentially made from orally ingested l-carnitine in both mice and humans, and l-carnitine supplementation has been shown to accelerate atherosclerosis development in murine models of the disease (6, 26). Parallel clinical studies show that omnivores have higher circulating concentrations of l-carnitine than vegans or vegetarians, and that elevated plasma concentrations of l-carnitine in subjects is associated with incident CVD risks (e.g., heart attack, stroke, and death) independent of traditional CVD risk factors, but only in the presence of elevated TMAO (6). Despite these intriguing findings, it is unclear whether the mechanistic connection between l-carnitine ingestion and gut microbial production of TMA, and its downstream metabolite, TMAO, helps to explain the frequently observed association in epidemiologic studies of a dose-dependent relationship between red meat consumption and CVD risks (28–31). An improved understanding of oral l-carnitine metabolism in mammals and the potential involvement of gut microbiota–dependent processes is thus of considerable interest.
Upon more recent investigation of gut microbial metabolism of l-carnitine in mice, oral l-carnitine was discovered to not be directly converted into TMA via a simple 1-step process (i.e., a microbial l-carnitine TMA lyase activity; l-carnitine→TMA). Rather, the majority of orally ingested l-carnitine in mice produced a previously unappreciated intermediary metabolite, γ-butyrobetaine (γBB), in a gut microbiota–dependent step that occurred at a site anatomically proximal to, and at a rate 1,000-fold higher than the rate of the formation of TMA (26). Historically, γBB was discovered because of its role as the proximate endogenous biosynthetic intermediate in l-carnitine synthesis in mammals, a multistep pathway that generates l-carnitine from lysine (32–34). Dietary supplementation of mice with γBB was shown to produce both TMA and TMAO, and to accelerate atherosclerosis, but only in the presence of gut microbiota (26). Thus, studies in mice have revealed a multistep metaorganismal pathway that is initiated by sequential gut microbiota–dependent conversions of oral l-carnitine into an atherogenic intermediate, γBB, which is then converted into TMA, the immediate precursor for host hepatic transformation into TMAO (i.e., l-carnitine γBB→TMA→TMAO). Whether γBB is a major product of gut microbial catabolism of dietary l-carnitine in humans, and the relationship of chronic dietary patterns (e.g., omnivorous versus vegan/vegetarian) and l-carnitine exposure to γBB metabolism in humans, are unclear. Herein, we explore the role of the gut microbiota in γBB generation in humans, and the impact of preceding dietary history and oral l-carnitine supplementation on both γBB generation and catabolism to TMA/TMAO in subjects. Finally, we also identify and characterize human fecal microbial community members that participate in the conversion of l-carnitine into TMA via the generation and catabolism of γBB.
Dietary l-carnitine produces γBB in a gut microbiota–dependent manner in humans. In prior studies we showed gut microbiota–dependent TMA and TMAO generation following oral l-carnitine ingestion in omnivores, but virtually nonexistent TMA/TMAO formation from oral l-carnitine in long-standing (>1 year) vegans and vegetarians (6). However, we did not look for γBB formation in those studies. Therefore, in initial pilot clinical studies (Figure 1), we first explored (in omnivores) whether γBB could be formed from l-carnitine following oral ingestion of heavy isotope–labeled l-carnitine (d3-l-carnitine), and the potential participation of gut microbiota in that reaction. At the initial baseline visit, serial venous sampling performed after oral d3-l-carnitine challenge revealed rapid increases in plasma concentrations of d3-l-carnitine, and subsequent increases in d3-γBB and d3-TMAO following a lag phase (Figure 1, A–C, filled circles). After the initial baseline challenge, subjects were placed on a week-long oral regimen of a cocktail of poorly absorbed antibiotics previously shown to effectively suppress intestinal microbiota (6), and then the d3-l-carnitine challenge was repeated (Figure 1, open circles). Complete suppression of d3-TMAO and almost complete suppression of d3-γBB formation were observed (Figure 1). These results are consistent with results observed in mice (26) and strongly support a role for gut microbiota in γBB generation from dietary l-carnitine in humans. Finally, examination of plasma d3-l-carnitine concentrations before versus after exposure to the antibiotics cocktail also showed no differences (Figure 1C).
γBB and TMAO production from l-carnitine is a gut microbiota–dependent process in humans. Subjects (n = 5) ingested a capsule containing d3-l-carnitine (250 mg; t0), after which serial plasma aliquots were obtained at the times shown (Baseline, filled circles). After a week-long regimen of oral broad-spectrum antibiotics to suppress the intestinal microbiota, the oral l-carnitine challenge was repeated (+ Abx, open circles). Stable isotope dilution LC-MS/MS was used to quantify d3-TMAO (A), d3-γBB (B), and d3-l-carnitine (C) in plasma collected from sequential venous blood draws at the noted times. Time points are represented as mean ± SEM plasma concentrations, and a zero-inflated linear mixed-effects model was used to compare subjects before and after antibiotic exposure.
Ingestion of γBB produces TMAO in a gut microbiota–dependent manner in humans. We next sought to test whether gut microbiota–formed γBB could produce TMAO in humans. Heavy isotope–labeled γBB (d9-γBB) was synthesized and used to perform a similar oral “γBB challenge” of subjects (n = 6 omnivores). Following oral ingestion, rapid elevation in plasma concentrations of both d9-γBB and d9-l-carnitine was observed, followed by d9-TMAO generation after a lag phase (Figure 2, A–C, filled circles). Interestingly, after a week-long suppression of the gut microbiota with oral broad-spectrum antibiotics cocktail, a rechallenge with oral d9-γBB showed complete suppression of d9-TMAO formation in subjects, confirming gut microbiota–dependent conversion of γBB into TMAO (Figure 2A, open circles). The production of d9-l-carnitine from oral d9-γBB, however, was not suppressed with the oral antibiotics; moreover, on closer inspection, while the peak plasma concentration of d9-γBB (2 hours) after oral ingestion significantly decreased by 8 hours (P < 0.05), the peak blood concentrations of d9-l-carnitine showed a relative plateau between 2 and 8 hours (Figure 2, B and C). These observations indicate that d9-l-carnitine production from oral d9-γBB occurs via a mechanism that is not suppressed by antibiotics, and are consistent with expected results from the endogenous l-carnitine biosynthetic pathway (i.e., host conversion of γBB to l-carnitine during carnitine biosynthesis) (32–34). Finally, examination of plasma d9-γBB concentrations before versus after exposure to the antibiotics cocktail showed no differences (Figure 2B).
TMAO is a gut microbiota–dependent product of γBB in humans. Subjects (n = 6) received oral d9-γBB (250 mg; t0), and then serial plasma aliquots were obtained at the noted time points (Baseline, filled circles). After a week-long regimen of oral broad-spectrum antibiotics to suppress the intestinal microbiota, the oral d9-γBB challenge was repeated (+ Abx, open circles). Stable isotope dilution LC-MS/MS was used to quantify d9-TMAO (A), d9-γBB (B), and d9-l-carnitine (C) in plasma collected from sequential venous blood draws at the noted times. Time points are mean ± SEM plasma concentrations, and a zero-inflated linear mixed-effects model was used to compare subjects before and after antibiotic exposure.
Omnivores generate significantly more TMAO than vegans/vegetarians from oral L-carnitine because of marked increase in gut microbial conversion of γBB into TMA. We had previously reported that d3-l-carnitine challenge in omnivores showed significantly elevated d3-TMAO generation in comparison with vegans/vegetarians (6); we first recapitulated these findings and confirmed that omnivores (n = 15) have a much greater capacity to generate d3-TMAO from orally ingested d3-l-carnitine than vegans and vegetarians (n = 9) (Figure 3A, left panel). To determine the origins of this difference, we next explored each step in the multistep reaction. Notably, despite the dramatic difference in d3-TMAO production from oral d3-l-carnitine in omnivores versus vegans/vegetarians, the difference observed in the first step of that gut microbiota–mediated transformation, conversion of d3-l-carnitine to d3-γBB, was not significant, and if anything showed a trend toward a lower conversion rate in the omnivores (P = 0.051; Figure 3A, right panel). Further, plasma concentrations of d3-γBB observed following oral d3-l-carnitine challenge were approximately 20-fold lower relative to plasma d3-TMAO (Figure 3A, left vs. right panel). We next examined fasting endogenous plasma γBB concentrations before versus after 1-week exposure to the oral antibiotics cocktail in subjects (n = 9 omnivores) and noted no significant differences (P = 0.55; Figure 3B). Moreover, while oral d3-l-carnitine ingestion produced d3-γBB, comparison of endogenous fasting levels of γBB in an expanded number of omnivores (n = 40) versus vegans/vegetarians (n = 32) failed to show any significant differences (P = 0.38; Figure 3C) and was notable also for the relatively low plasma levels of γBB observed (in general, approximately 5- to 10-fold reduced compared with TMAO). Despite the expanded number of subjects examined, no difference in endogenous plasma l-carnitine levels was observed between the vegans/vegetarians (n = 32) and the omnivores (n = 40) (mean ± SEM: omnivores 31.3 ± 2.5 vs. vegans/vegetarians 39.1 ± 4.3 μM; P = 0.18; Supplemental Figure 1; supplemental material available online with this article; https://doi.org/10.1172/JCI94601DS1).
γBB is a major gut microbiota metabolite of l-carnitine, and TMA formation from γBB is influenced by dietary habits. (A) Plasma d3-TMAO and d3-γBB concentrations in vegans/vegetarians (d3-TMAO, n = 9; d3-γBB, n = 9) versus omnivores (d3-TMAO, n = 15; d3-γBB, n = 12) participating in an oral d3-l-carnitine (250 mg) challenge. The left panel illustrates the marked differences in d3-TMAO generation previously reported in omnivores versus vegans/vegetarians. The right panel shows a small difference in plasma d3-γBB concentration between omnivores and vegans/vegetarians. Data represent mean ± SEM. A Mann-Whitney test was used to compare the AUCs between dietary groups. (B) Box-and-whisker plots of fasting plasma concentrations of γBB from subjects (n = 9) before versus after 1 week of oral broad-spectrum antibiotics to suppress gut microbiota. Boxes represent the 25th, 50th, and 75th percentiles, and whiskers represent the 10th and 90th percentiles. Differences were assessed using a Wilcoxon matched-pairs test. (C) Fasting plasma concentrations of γBB in vegans/vegetarians (n = 32) versus omnivores (n = 40). Boxes represent the 25th, 50th, and 75th percentiles, and whiskers represent the 10th and 90th percentiles. A Mann-Whitney test was used to assess differences between groups. (D) Baseline human fecal metabolite studies in vegans/vegetarians and omnivores (n = 10 each group). Fecal samples were incubated anaerobically with d3-l-carnitine, and d3-TMA and d3-γBB were quantified by LC-MS/MS. Data are expressed as mean ± SEM. A Mann-Whitney test was used to assess differences between groups. (E) Baseline human fecal metabolite studies in vegans/vegetarians (n = 10) versus omnivores (n = 10). Fecal samples were incubated with d3-l-carnitine or d9-γBB as indicated. Metabolites were quantified by LC-MS/MS. Data are expressed as mean ± SEM. A Mann-Whitney test was used to assess differences between groups.
Given that isotope tracer studies show γBB is clearly formed following oral l-carnitine ingestion, and similarly, isotope-labeled γBB was readily converted into isotope-labeled TMA/TMAO following oral ingestion, we hypothesized that low overall plasma concentrations of gut microbiota–produced γBB in humans may be the result of microbial γBB breakdown into TMA, predominantly occurring in the lower intestinal track (colon) distal to the absorption of most nutrients like l-carnitine and γBB. To explore this possibility, we characterized human fecal polymicrobial metabolism under ex vivo anaerobic conditions using distinct heavy isotope–labeled substrates — i.e., synthetic d3-l-carnitine and d9-γBB, allowing us to monitor d3-TMA (from carnitine) and d9-TMA (from γBB) at the same time — from both omnivores (n = 10) and vegans/vegetarians (n = 10) (Figure 3, D and E). Multiple notable findings were observed. First, quantitatively, the generation of d3-γBB from d3-l-carnitine by fecal microbiota under anaerobic culture was approximately 50-fold higher than d3-TMA formation in omnivore and vegan/vegetarian alike (P < 0.001; Figure 3D). These results indicate that γBB is a major gut microbial metabolite formed from oral l-carnitine in humans (for both omnivores and vegans/vegetarians). Second, fecal microbiota from omnivores (vs. vegans/vegetarians) showed a significantly enhanced (P = 0.02) enzymatic capacity to produce TMA from l-carnitine (Figure 3E, left). And yet, third, no difference was observed in the fecal transformation of l-carnitine to γBB in vegans/vegetarians compared with omnivores (P = 0.54; Figure 3E, middle). Finally, results of the fecal polymicrobial culture studies indicate that the marked increased generation of TMA (and TMAO) from oral l-carnitine in omnivores versus vegans/vegetarians appears to be due to significantly (up to 10-fold) greater gut microbial conversion of γBB to TMA in omnivores relative to vegans/vegetarians (i.e., chronic exposure to l-carnitine in an omnivorous diet is associated with an increase in microbial capacity to catalyze the transformation of γBB to TMA; P = 0.04; Figure 3E). Collectively, these data suggest that in the multistep metabolism of dietary l-carnitine into TMAO (i.e., l-carnitine→γBB→TMA→TMAO), gut microbial metabolism of l-carnitine→γBB occurs rapidly in omnivore and vegan/vegetarian alike, and the latter microbial transformation of γBB to TMA is the one markedly enhanced in omnivores over vegans/vegetarians (i.e., influenced by chronic dietary habits; Figure 3E).
Chronic dietary l-carnitine supplementation enhances gut microbiota–dependent generation of TMAO. The significant differences noted in overall metabolism of oral l-carnitine→TMA/TMAO in omnivores and, to a lower extent, in vegans/vegetarians are a striking finding. We therefore sought to further explore the impact of chronic daily dietary l-carnitine exposure on these differences. Both vegans/vegetarians (n = 7) and omnivores (n = 10) gave consent and were instructed to continue with their typical diets but with the addition of supplemental l-carnitine (500 mg l-carnitine tartrate per day, provided in a Vegicap). Subjects were monitored at baseline, at 1 month, and after 2–3 months of continuous daily supplemental l-carnitine ingestion by examination of the rate of plasma appearance of both d3-TMAO (Figure 4A) and d3-γBB (Figure 4C) following oral d3-l-carnitine challenge. In addition, fasting plasma levels of endogenous TMAO (Figure 4B) and γBB (Supplemental Figure 2) were monitored. At baseline, vegans/vegetarians showed minimal synthetic capacity to produce d3-TMAO following ingestion of d3-l-carnitine, whereas omnivores readily generated d3-TMAO (Figure 4A). After 1 month of daily l-carnitine supplementation, enhancement in the formation of d3-TMAO following d3-l-carnitine ingestion was observed in vegans/vegetarians and omnivores alike (Figure 4A). Continuation of daily l-carnitine supplementation for at least an additional month resulted in no further increase in d3-l-carnitine→d3-TMAO transformation in omnivores, but continued to increase d3-TMAO generation in vegans/vegetarians following oral d3-l-carnitine challenge (Figure 4A). Examination of individual plots of plasma d3-TMAO production from oral d3-l-carnitine challenges among vegans/vegetarians (n = 7) demonstrated that the mean increase observed was driven by only a subset (n = 3) of subjects, with over half (n = 4) of the vegans/vegetarians demonstrating essentially no metabolic capacity to convert oral d3-l-carnitine into d3-TMAO even after months of l-carnitine supplementation (Supplemental Figure 3). Fasting plasma concentrations of TMAO in both omnivores and vegans/vegetarians increased upon chronic (1 month) l-carnitine supplementation, but did not significantly further increase with another month of supplementation (Figure 4B). Interestingly, in both vegans/vegetarians and omnivores, chronic l-carnitine supplementation induced no significant differences in the rates of d3-γBB formed following oral d3-l-carnitine challenge or in fasting plasma γBB concentrations (Figure 4C and Supplemental Figure 2).
l-Carnitine supplementation enhances the synthetic capacity of gut microbiota to form TMAO. (A) Plasma d3-TMAO concentrations in sequential venous blood draws after oral d3-l-carnitine challenge in vegans (n = 7) and omnivores (n = 8) at baseline, visit 1 (V1, 1 month), and visit 2 (V2, 2–3 months). Data represent mean ± SEM. A zero-inflated linear mixed-effects model reveals that plasma d3-TMAO is significantly higher after l-carnitine supplementation. (B) Plasma TMAO concentrations in vegans (n = 7) and omnivores (n =10) at baseline and following daily l-carnitine supplementation at visit 2 (V1, 1 month), and visit 3 (V2, 2 months). Boxes represent the 25th, 50th, and 75th percentiles, and whiskers represent the 10th and 90th percentiles. A repeated-measures 1-way ANOVA test was used to assess differences between baseline visits. (C) Plasma d3-γBB concentrations in sequential venous blood draws after oral d3-l-carnitine challenge in vegans/vegetarians (n = 7) and omnivores (n = 5) at baseline, visit 1 (V1, 1 month), and visit 2 (V2, 2 months). Data represent mean ± SEM. A zero-inflated linear mixed-effects model reveals that plasma d3-γBB production is not significantly higher after l-carnitine supplementation in vegans/vegetarians or omnivores.
We next sought to biochemically characterize microbial transformation activities in feces of subjects before versus after l-carnitine supplementation. A subset of subjects (n = 7 omnivores, n = 6 vegans/vegetarians) consented to provide feces at both baseline and the end of the study following at least 2 months of l-carnitine supplementation for analyses (Figure 5). At baseline, comparisons between omnivores and vegans/vegetarians showed no significant differences in any of the fecal microbial metabolic transformations monitored (d9-l-carnitine→d9-TMA, d9-l-carnitine→d9-γBB, and d9-γBB→d9-TMA; P = 0.52, P = 0.63, P = 0.35, respectively) (Figure 5, A–C). However, following chronic l-carnitine supplementation, fecal samples recovered from omnivores showed significantly enhanced generation of d9-TMA from either d9-l-carnitine or d9-γBB relative to vegan/vegetarian fecal samples (P < 0.01 and P = 0.01, respectively; Figure 5, A and C). Further, while dietary l-carnitine supplementation induced no differences in fecal transformation of the first step of the l-carnitine→γBB→TMA/TMAO metaorganismal pathway in either omnivores or vegans/vegetarians, dietary l-carnitine provision induced enhanced fecal microbial transformation of the second microbial step in the overall pathway (i.e., d9-γBB→d9-TMA) in omnivores (P = 0.02), but not vegans/vegetarians (P = 0.69) (Figure 5C).
l-Carnitine supplementation does not enhance the synthetic capacity of gut microbiota to produce γBB from l-carnitine, but does enhance gut microbiota–dependent transformation of γBB into TMA. At baseline and after l-carnitine supplementation (l-Carn; 2–3 months), human fecal metabolite studies (n = 6 omnivores and n = 7 vegans/vegetarians) in the conversion of d9-l-carn to d9-TMA (A), d9-l-carn to γBB (B), or d9-γBB to d9-TMA (C). Fecal samples were incubated with either d9-l-carnitine or d9-γBB as described in Methods, and d9-TMA and d9-γBB were quantified by LC-MS/MS. A Wilcoxon matched-pairs test was used to assess for differences between groups.
Multiple organisms are involved in the gut microbial production of TMA from l-carnitine. Since l-carnitine catabolism is mediated by microbial enzymes, we sought to identify the organisms involved in anaerobic l-carnitine degradation in fecal samples from a healthy omnivore donor (Figure 6A). In previous studies, single gastrointestinal microbial strains were reported to be unable to catabolize l-carnitine into TMA (35). We therefore hypothesized that multiple organisms are needed for catabolism of l-carnitine to TMA presumably with γBB as an intermediate. Therefore, we isolated not only single microbial colonies from feces but also subcommunities of 2–3 and 4–5 colonies, and tested the ability of each single isolate or subcommunity to produce TMA from l-carnitine. Though no single isolate produced TMA, 2 subcommunities out of 768 did produce TMA, and 1 of those subcommunities was further fractionated using a similar strategy as before (i.e., single, 2–3, and 4–5 colonies; Figure 6A). A noticeable enrichment in the number of TMA-producing subcommunities was observed, but again no individual isolate could perform the l-carnitine→TMA transformation. The subcommunity producing the most TMA was spread and plated once more, and 100 colonies of the community were preliminarily identified by proteomics analyses using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (36). The colonies were pooled based on best-match organism into 5 species pools (SP1 through SP5; Supplemental Table 1). Individual pools and combinations were evaluated for l-carnitine→TMA activity using a fractional factorial design (Figure 6B). Absence of either SP2 or, to a lesser extent, SP5 abolished the l-carnitine→TMA activity, whereas maximum production of TMA was attained only when both SP2 and SP5 were present. Each species pool (SP2 and SP5) was further subfractionated into individual colonies, and all members were evaluated alone or in combination with the members of the other pool. Only the combination of SP5-56 or SP5-62 with SP2-71 yielded maximum TMA production (Figure 6C). These data confirm our hypothesis and demonstrate that at least 2 different organisms are required for the anaerobic catabolism of l-carnitine to TMA. Both SP5-56 and SP5-62 were identified as isolates of Eggerthella lenta by 16S-rRNA gene sequencing. Further characterization of SP2-71 indicated that it was not a single strain, but a combination of 4 microbes (Supplemental Figure 4A). Of the 4 microbes, 1 had not been reported at the time of isolation, but showed 99% 16S-rRNA gene sequence identity (Supplemental Figure 4B) with an organism recently isolated by others and classified as Emergencia timonensis (37). Interestingly, E. timonensis (SP2-71.3) produced TMA in the absence of molecular oxygen, suggesting a novel microbial pathway for l-carnitine catabolism independent of the CntA/B oxygenase (25, 26).
l-Carnitine catabolism to TMA involves multiple microorganisms. (A) l-Carnitine–enriched fecal communities were plated on solid media. Single microbial colonies and subcommunities of up to 3 and 4+ colonies were picked and tested for their l-carnitine→TMA activity. The top producing community was refractionated to select the highest TMA-producing subcommunity. (B) Species pools (SP1 through SP5) were evaluated alone or in combination for l-carnitine→TMA activity in n = 2 replicate values. Data are expressed as the mean. (C) Combinations of individual members of SP2 and SP5 were evaluated for TMA production. Concentrations of d9-TMA were determined by stable isotope dilution LC-MS/MS.
Human commensal utilization of l-carnitine is decoupled from TMA production and generates γBB as intermediate. We next studied which of the isolated human commensals were necessary and sufficient to metabolize l-carnitine to TMA. Each of the microbes contained in species pool SP2-71 was evaluated alone or in combination with E. lenta (species pool SP5-62; Figure 7A). l-Carnitine was always consumed in the presence of E. lenta (SP5-62), regardless of whether other microbes were present. However, TMA production was decoupled from l-carnitine utilization and was only produced when both E. lenta (SP5-62) and SP2-71.3 (or the entire SP2-71 pool) were present, which suggests that E. lenta (SP5-62) is associated with l-carnitine consumption and SP2-71.3 is responsible for TMA production (Figure 7A). We mined the genome of E. lenta (SP5-62) for genes likely to be associated with l-carnitine utilization and noticed genes of the caiTABCDE gene operon that encode for a crotonobetaine reductase, l-carnitine-CoA transferase, and l-carnitine-CoA ligase, among other genes (Figure 7B). Reasoning that the enzymes encoded by these genes could be responsible for the utilization of l-carnitine and its conversion to γBB (Figure 7C), we used comparative genomics tools to identify 3 other organisms that contain the caiTABCDE gene operon (Supplemental Figure 5), and assessed their ability to consume l-carnitine and produce γBB (Figure 8). Although none of the 3 microbes, Escherichia fergusonii, Edwardsiella tarda, and Proteus penneri, produced TMA, all 3 consumed l-carnitine while producing γBB, suggesting that the utilization of l-carnitine is associated with the presence of the caiTABCDE genes. The combination of any of the 3 microbes with E. timonensis (SP2-71.3) led to anaerobic, oxygen-independent, TMA production from l-carnitine and consumption of γBB (Figure 8). The E. timonensis type strain SN18 (37) performed very similarly to E. timonensis SP2-71.3 in this study (data not shown).
Anaerobic microbial l-carnitine consumption is associated with the presence of the microbial caiTABCDE genes. (A) Individual SP2-71 microbes were evaluated alone or in combination with E. lenta SP5-62 for l-carnitine→TMA activity. Data are expressed as the mean of the d9-l-carnitine peak ratio and d9-TMA concentration in n = 2 replicate values. (B) E. lenta genome mining revealed the presence of the caiTABCDE gene operon. Data are expressed as the mean. (C) l-Carnitine→γBB pathway involving enzymes encoded by the caiTABCDE gene operon. Crotono, crotonobetaine.
CaiTABCDE gene–expressing microbes consume l-carnitine, but only make TMA in the presence of E. timonensis. Concentrations of l-carnitine and TMA were determined by stable isotope dilution LC-MS/MS in n = 3 replicate values. Data are expressed as mean ± SEM.
During l-carnitine catabolism by human gut commensals and fecal polymicrobial anaerobic cultures, γBB accumulates as an intermediate before it is anaerobically converted to TMA. We then determined the kinetics of consumption of l-carnitine and production of γBB and TMA by P. penneri (ATCC 35198), one of the human commensals shown to produce γBB, alone or in combination with E. timonensis (SP2-71.3) (Figure 9A). Addition of l-carnitine to an anaerobic culture of P. penneri alone (in M9 minimal medium) resulted in quantitative transformation of l-carnitine to γBB within 4 hours with no TMA production. E. timonensis alone did not consume l-carnitine or produce TMA from l-carnitine. However, the combination of P. penneri and E. timonensis led to a transient accumulation of γBB that was subsequently consumed with concomitant production of TMA (Figure 9A, top). When M9 minimal medium was instead supplemented with γBB, P. penneri alone was unable to consume γBB or produce TMA, whereas only E. timonensis was sufficient to produce TMA from γBB in the presence or absence of P. penneri (Figure 9A, bottom). To our knowledge, this is the first report of a single microbial strain capable of producing TMA from one of the metabolites of the l-carnitine pathway under anaerobic conditions. Moreover, kinetic analyses reveal that the production of γBB precedes production of TMA, consistent with γBB being needed to induce the γBB→TMA phenotype.
Anaerobic microbial l-carnitine catabolism generates γBB as an intermediate. (A) Kinetic changes of l-carnitine, γBB, and TMA were determined in cultures of P. penneri alone or in combination with E. timonensis, SP2-71.3, supplemented with l-carnitine (top panel) or γBB (bottom panel). Concentrations were determined in n = 2 replicate values. Data are expressed as the mean. (B) Selected human fecal communities from 4 different donors were studied for their l-carnitine→γBB→TMA activity sampling (n = 1) every 4 hours for 32 hours. Concentrations of l-carnitine, γBB, and TMA were determined by stable isotope dilution LC-MS/MS. All human subjects are displayed in Supplemental Figure 6.
To assess whether the transient buildup of γBB in vitro with only 2 microbial strains represents the biochemical transformations that occur in the presence of gastrointestinal polymicrobial communities, the anaerobic metabolism of l-carnitine by fecal communities from 12 human healthy donors (all omnivores) was studied. For illustrative purposes, biochemical transformations characteristic of omnivores following carnitine supplementation (subjects 1 and 7) and vegans or vegetarians (i.e., little TMA generation: subjects 10 and 12) are shown in Figure 9B, while data from all 12 subjects are shown in Supplemental Figure 6. The communities of all 12 subjects converted the majority of l-carnitine to γBB within 12 hours of incubation, although not all subjects produced TMA from γBB by 32 hours (Figure 9B). Moreover, γBB formation (before TMA generation) was quantitatively associated with l-carnitine consumption, and when produced, TMA formation was quantitatively associated with γBB consumption. Thus, the demonstrated kinetics of generation and decay of the metabolites monitored followed the anticipated precursor→product relationships, and were entirely consistent with the initial microbial conversion of l-carnitine to γBB, followed by transformation of γBB to TMA, reaction kinetics akin to the dynamics of l-carnitine catabolism observed with the human commensals P. penneri and E. timonensis.
Historically, γBB is known for its role as the last biosynthetic intermediate in a series of endogenous reactions used to synthesize l-carnitine from lysine (38). Given the important role of l-carnitine in fatty acid transport and metabolism, early studies of γBB (sometimes coined “pre–l-carnitine”) focused on its ability to form l-carnitine and facilitate fatty acid transport (32, 39). Early studies recognized that mammals: (i) lack the capacity to catabolize l-carnitine; (ii) gut microbial bacteria have the capacity to degrade l-carnitine into numerous products; and (iii) γBB may be a gut microbial product of l-carnitine after, in one study, trace concentrations of radiolabeled γBB were discovered in feces following oral ingestion of radiolabeled l-carnitine (39–41).
However, gut microbial formation and catabolism of γBB during oral l-carnitine metabolism in omnivores versus vegans/vegetarians, the human commensals that can utilize γBB as a nutrient, and the relationship of this metabolite to the metaorganismal TMAO pathway and CVD had not yet been explored.
An overview of dietary l-carnitine metabolism in humans, its relationship to both γBB and CVD risks, and the impact of preceding dietary pattern (omnivorous versus vegan/vegetarian), as well as chronic l-carnitine supplementation, as revealed by the present studies, are summarized in the scheme shown in Figure 10. Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (4–6, 12, 13, 16–18).
Scheme of l-carnitine and γBB metabolism in humans, links to gut microbial TMAO generation, and adverse cardiometabolic phenotypes. FMO, flavin-containing monooxygenase.
In addition to being a product of endogenous synthesis during l-carnitine generation, the present studies reveal that γBB is a major product of gut microbiota–dependent catabolism of orally ingested l-carnitine in humans, and is an intermediate in TMAO formation from l-carnitine. Moreover, the present studies reveal that the overall conversion of orally ingested l-carnitine to TMAO is a complex multistep process requiring an initial gut microbial l-carnitine→γBB conversion, followed by a second γBB→TMA transformation. Further, each step is carried out by different members of the gut microbial community. In addition, chronic dietary exposure to l-carnitine results in induction of enhanced gut microbiota catabolism of l-carnitine principally mediated by the second step — γBB catabolism producing TMA — resulting in greater TMAO generation in the omnivorous versus the vegan/vegetarian host (Figure 10). Importantly, γBB→TMA occurs in an anaerobic environment, which suggests that it is catalyzed not by the CntA/B oxygenase, but rather by a novel oxygen-independent enzymatic pathway for the conversion of metabolites of the l-carnitine pathway to TMA. It is also notable that the microbial γBB→TMA activity was induced even in some vegans/vegetarians despite continuation of a vegan/vegetarian diet, with l-carnitine supplementation. Despite this, the TMAO production capacity still appeared greater in omnivores compared with vegans/vegetarians. Remarkably, among the vegans/vegetarians examined, roughly half (4 of 7) demonstrated little or no capacity to produce more TMA or TMAO from l-carnitine, despite 2 or more months of the daily l-carnitine supplementation. Vegans/vegetarians unable to produce TMAO from l-carnitine had no antibiotic or probiotic exposure (like all subjects enrolled), were recruited from the same geographic region as the other subjects, and were apparently healthy with no significant known comorbidities. Given the low proportion of culturable human fecal commensals identified in the subculture experiments that were capable of promoting the second microbial transformation reaction (γBB→TMA), we speculate that the vegans/vegetarians unable to produce TMA and thus TMAO from l-carnitine simply lack microbial community members, like E. timonensis, that possess the polypeptide(s) required to promote the γBB→TMA metabolic transformation.
While the present studies reveal important aspects of l-carnitine metabolism in humans and illuminate the intermediary involvement of γBB in TMAO generation from dietary l-carnitine, multiple important questions remain before we can exploit this newfound knowledge to develop therapeutic interventions that target this pathway. In this study, human gut commensals that can metabolize l-carnitine into γBB, and γBB into TMA, are reported for the first time to our knowledge. Although examination of fecal polymicrobial cultures indicates both the presence and dietary induction of fecal microbial γBB→TMA transforming activity, the microbial gene(s) encoding this enzyme activity, an important potential therapeutic target, remain unknown. Early studies with the bacterial isolate Acinetobacter calcoaceticus have reported a link between γBB and TMA production (42). We also recently reported association studies between specific cecal microbial taxa and plasma γBB concentrations in mice (26). Further characterization of the human commensals capable of both reactions (l-carnitine→γBB and γBB→TMA), and discovery of the enzyme(s) responsible for TMA production, are of interest — particularly since this latter microbial step in the overall pathway appears to be the major one induced during chronic dietary red meat exposure (or directly with l-carnitine supplementation) in an omnivorous diet (Figure 10). While speculative, it is a logical extension that induction of the γBB→TMA transformation activity may play a role in the heightened CVD risks observed in omnivores versus vegans/vegetarians, or subjects who eat diets rich in red meat. This hypothesis merits further study.
One of the more surprising findings of the present studies was the relatively small amount of d3-γBB found in plasma compared with d3-TMAO after d3-l-carnitine challenge, especially after ex vivo fecal studies showed that γBB is a major metabolite of l-carnitine produced by human fecal polymicrobial cultures (43). Moreover, in mice we observed that chronic l-carnitine supplementation resulted in markedly elevated plasma γBB levels (more so than l-carnitine or TMAO), and it was the first step of the overall gut microbial catabolic pathway (i.e., l-carnitine→γBB) that was induced in mice following chronic l-carnitine dietary exposure (26). However, the present studies in humans revealed that γBB plasma levels do not increase significantly following chronic dietary exposure to supplemental l-carnitine, and no differences were observed in plasma levels of omnivores versus vegans/vegetarians. While the origins of the observed differences between mice and humans with respect to the l-carnitine→γBB→TMA→TMAO pathway are not clear, the fact that the second reaction in the conversion of l-carnitine into TMA (i.e., γBB→TMA) showed marked induction with dietary exposure in subjects likely plays a major role in the observed differences. Still to be determined is whether this gain of function is the result of changes in the structure or the function of the gastrointestinal microbial community. That there exist interspecies differences in biosynthetic pathways mediated by gut microbiota metabolism between mice and humans is consistent with numerous other examples of how gut microbiomes of mammalian species can differ (44).
Multiple recent meta-analyses have confirmed that plasma TMAO levels are dose-dependently associated with incident CVD and mortality risks across multiple patient populations and geographic areas (45–47). In fact, in one meta-analysis, each 10-μM increase in TMAO was reported to be associated with an absolute 7.6% increased risk of all-cause mortality (45). It is also worth noting that animal model studies have illustrated a mechanistic contribution of microbial TMA and TMAO generation to enhanced development of atherosclerosis, platelet reactivity and thrombosis, and both impairment in renal function and fibrosis, as well as adverse ventricular remodeling and heart failure (refs. 4–6, 13, 16, 17, and Figure 10). From a public health standpoint, the impact of TMAO elevation during l-carnitine supplementation is unknown, but both vegan/vegetarian and omnivore on average showed a greater than 10-μM increase in circulating TMAO levels with l-carnitine supplementation. Owing to the critical physiologic role of l-carnitine in cellular fatty acid metabolism, there has been a belief that oral consumption of l-carnitine is beneficial in energy expenditure, when, in fact, there is equivocal evidence for enhancement in healthy individuals (48–54). Yet use of l-carnitine by the nutritional supplement industry, particularly in some energy drinks, and to a lesser extent in some protein supplements, is generally regarded as safe. Notably, the dose of l-carnitine supplement that subjects received in this study was well within the range of normal dietary exposure, and is comparable to the amount of l-carnitine in a single can of some energy drinks marketed presently, as well as the content of l-carnitine in a typical restaurant-portion steak dinner (55, 56). The present studies demonstrate that frequent dietary l-carnitine, even among some vegans/vegetarians, induces the gut microbiota’s capacity to produce TMAO, and may thus foster proatherogenic processes (6). It is also relevant that in recent studies, we have shown that TMAO directly interacts with human platelets (both isolated and in whole blood), altering stimulus-dependent calcium signaling and promoting platelet hyperresponsiveness (4). Moreover, elevated systemic concentrations of TMAO enhanced thrombosis potential in vivo in animal models (4), and in recent clinical intervention studies, elevation in plasma TMAO induced with dietary choline supplementation altered platelet hyperresponsiveness in subjects (omnivores and vegans/vegetarians alike), as monitored by platelet aggregometry (17). The present studies show that chronic exposure to dietary l-carnitine similarly elevates TMAO concentrations. Whether parallel alteration in platelet responsiveness and long-term thrombosis risk occurs in subjects remains to be determined, but as noted above, elevated serum levels of carnitine are associated with enhanced risks of major adverse cardiovascular events (6).
There remain some limitations to these studies. First, while antibiotic suppression is used to invoke a role for gut microbiota in the generation of the metabolite(s) monitored, antibiotics can also have direct effects on the host, altering normal metabolism (57, 58). Secondly, we did not have access to hepatic tissues in subjects, and cannot definitely rule out that there may be some dietary influence on flavin monooxygenase–dependent conversion of TMA to TMAO. Similarly, we did not explore whether dietary patterns differentially influence renal excretion of TMAO. Finally, the studies used relatively small numbers of individuals, and thus do not allow for investigation of significant differences in sex, race, or other subgroups. We are thus cautious about the generalizability of these studies to greater populations.
In summary, the present studies add to our understanding of gut microbiota involvement in nutrient metabolism relevant to red meat ingestion, a Western diet, and CVD risks. Our studies reveal that l-carnitine→TMA is a multistep biochemical transformation mediated by multiple members of the gut microbial community via formation of an intermediate, γBB, previously shown to be proatherogenic in animal models. These studies also indicate that daily consumption of l-carnitine, even while maintaining a vegan/vegetarian diet, can induce the gut microbiota–dependent γBB→TMA transformation, resulting in heightened formation of the atherogenic and prothrombotic metabolite TMAO. Finally, our studies provide important insights for efforts aimed at development of therapeutic interventions designed to inhibit dietary l-carnitine conversion into TMAO in humans.
Materials and general procedures. Human fasting lipid profiles and blood chemistries were measured using the Abbott ARCHITECT platform, model ci8200 (Abbott Diagnostics). Human subject gut microbiota suppression was achieved using a cocktail of oral poorly absorbed antibiotics as previously described (7). All stable isotope–labeled compounds used in the present studies were synthesized as described below. Plasma levels of endogenous and stable isotope–labeled l-carnitine, γBB, and TMAO were determined by stable isotope dilution liquid chromatography–tandem mass spectrometry (LC-MS/MS) in positive multiple reaction monitoring (MRM) mode as previously described (6) using a Shimadzu 8050 triple quadrupole mass spectrometer with ultra-HPLC interface. Laboratory personnel performing MS analyses were blinded to sample group allocation and clinical data during analysis.
Research subjects. Healthy subjects were enrolled in a study named CARNIVAL (NCT01731236; https://clinicaltrials.gov/ct2/show/NCT01731236), which studies gut microbial metabolism of l-carnitine in subjects. Subjects were divided into vegan/vegetarian or omnivore groups based on extensive dietary questioning. To be defined as vegan/vegetarian, the subject gave a history of no meat consumption for the preceding 1-year period. Baseline plasma and/or feces samples were collected. A subset of subjects were given oral heavy isotope–labeled l-carnitine challenge testing as outlined below. Subjects performed the oral l-carnitine challenge test by consuming 250 mg of synthetic d3(methyl)-l-carnitine within a capsule (Vegicap, Catalent), followed by serial venous plasma draws collected in EDTA vacutainer tubes for d3-l-carnitine metabolite quantification. Other subjects underwent a similar γBB challenge test following oral administration of 250 mg of synthetic d9(methyl)-γBB (also provided in Vegicap). Dietary habits of subjects were determined using a questionnaire similar to that conducted by the Atherosclerotic Risk in Community (ARIC) study (59). Subjects were excluded from l-carnitine or γBB challenge testing if they were pregnant, had chronic illness (including a known history of heart failure, renal failure, pulmonary disease, gastrointestinal disorders, or hematologic diseases), had an active infection, received antibiotics within 2 months of study enrollment, used any over-the-counter or prescription probiotic or bowel-cleansing preparation within the past 2 months, ingested yogurt within the past 7 days, or had undergone bariatric or other intestinal (e.g., bowel resection/reconstruction) surgery. Subjects were recruited by self-selection at Cleveland Clinic. Neither subject participants nor those administering the intervention were blinded, though investigators performing MS analyses were blinded to sample identities other than sample identification codes. Where indicated, a subset of subjects were instructed to continue with their current diet but, in addition, were placed on oral l-carnitine supplement (500 mg l-carnitine tartrate daily) and rechallenged in follow-up visits at 1 month and 2–3 months from baseline. All but 1 omnivorous subject completed all 3 visits. Some subjects had only baseline and 24-hour measurements taken of d3-l-carnitine metabolites. Others underwent the entire l-carnitine or γBB challenge (i.e., had samples drawn 0, 2, 4, 6, 8, and 24 hours after ingestion of the indicated heavy isotope compound). If subjects experienced side effects of the noted treatment including, but not limited to, nausea, vomiting, diarrhea, or fever, they were instructed to stop treatment. If subjects failed to comply or did not tolerate the intervention, they were removed from the relevant analysis. Subjects were paid for each complete participated visit. A total of 35 subjects were enrolled in the heavy-isotopologue challenge studies, which included either d9-γBB or d3-l-carnitine. Subjects were stratified by diet into n = 11 vegans/vegetarians and n = 24 omnivorous subjects. One enrolled vegan/vegetarian subject was later excluded as a result of reported nausea and a low BMI, 1 omnivorous subject declined the challenge after being enrolled and giving consent, 3 subjects enrolled in the antibiotic suppression arms did not tolerate the antibiotics (gastrointestinal distress) and were thus excluded from the study, and 2 subjects admitting noncompliance with daily l-carnitine supplementation were only included in baseline challenge studies. Thus, n = 10 vegans/vegetarians and n = 20 omnivorous subjects were included in the studies (see Supplemental Table 2 for baseline data). Baseline data for 3 omnivorous subjects were unavailable. Six of 7 vegans/vegetarians and 7 of 8 omnivores enrolled in the l-carnitine supplementation and challenge studies were used in the exploratory fecal metabolite studies based on availability of fecal samples. A second group of self-selected healthy volunteers on the Procter & Gamble campus (all omnivores) gave consent and donated fecal samples for microbial culture and biochemical analyses.
Human l-carnitine and d9-γBB challenge test. Adults who had given consent performed a 12-hour fast overnight before performing the l-carnitine challenge test, which involved a baseline blood sample and then oral consumption (t0 at time of initial ingestion) of capsules containing 250 mg d3-l-carnitine (under investigational new drug exemption). In a second group of subjects, a d9-γBB challenge was performed with 250 mg d9- γBB. Following the baseline blood draw and ingestion of the capsule of isotope tracer, sequential venous serial blood draws were performed at noted time points for the determination of d9-γBB metabolites. Urine was collected as a spot baseline sample and a sample after 24-hour challenge. After completion of the initial l-carnitine or γBB challenge (baseline or visit 1), an ensuing week-long treatment of oral antibiotics (7) was given to suppress intestinal microbiota, and the challenge (d3-l-carnitine or d9-γBB) was then repeated (visit 2).
Synthesis of d3-l-carnitine and d9-γBB. Synthesis of d3-l-carnitine was prepared as previously described (6, 60). Briefly, l-norcarnitine (3-hydroxy-4-dimethylaminobutyric acid) was prepared from l-carnitine (Chem Impex International) with thiophenol (Sigma-Aldrich) in N,N-dimethylaminoethanol (Sigma-Aldrich) and then was converted to its sodium salt with sodium hydroxide by the method of Colucci et al. (61). Sodium l-norcarnitine was recrystallized from ethanol and ethyl acetate before conversion to d3-l-carnitine. Some d3-l-carnitine was synthesized by dissolving sodium l-norcarnitine in methanol and reacting it with d3-methyl iodide (Cambridge Isotope Laboratories) in the presence of potassium hydrogen carbonate to give d3-l-carnitine per Chen and Benoiton (62). d3-l-Carnitine was isolated by silica gel column rinsing with methanol elution. The product was dried via azeotropic distillation of absolute ethanol and subsequently recrystallized from ethanol and acetone. The crystalline product was dried over P2O5 in vacuo and stored in a desiccator by refrigeration. Structural analysis of d3-l-carnitine was confirmed by both high-resolution MS and NMR, and found to be more than 98% pure by LC-MS, NMR, and TLC.
Synthetic d9-γBB was prepared as a chloride salt from γ-aminobutyric acid in methanol with potassium hydrogen carbonate and d3-methyl iodide, as previously described (26). Briefly, (3-carboxypropyl)trimethyl(d9)ammonium chloride (d9-butyrobetaine chloride, d9-BB) was prepared from γ-aminobutyric acid in methanol with potassium hydrogen carbonate and d3-methyl iodide (all from Sigma-Aldrich) (63). The reaction lasted 72 hours and was transferred onto a bed of silica gel (pores 60 Å, particles 40–60 μm; Agela Technologies) and equilibrated and washed in methanol. Rotary evaporation was used to yield the crude product, which was dissolved in water and titrated to pH 7.2. Further water was azeotropically removed by rotary evaporation with ethanol. The product was dissolved in absolute ethanol, filtered, concentrated to dryness by rotary evaporation, and dissolved in hydrochloric acid. The product was redissolved in a minimal amount of methanol and treated with 5 volumes of acetone to precipitate crystal formation. The crystals were filtered under suction, and dried under vacuum at 60°C. All reagents were obtained from Sigma-Aldrich unless otherwise indicated. Structural analysis of d9-γBB was confirmed by both high-resolution MS and multinuclear NMR, and found to be more than 98% pure by LC-MS, NMR, and TLC.
Isolation and characterization of microorganisms involved in l-carnitine catabolism. Fecal samples were collected from volunteer donors who gave informed consent. Subject privacy and confidentiality of identifiable information were protected. Immediately after fecal samples were collected, glycerol stock suspensions were generated and sample aliquots snap-frozen in liquid nitrogen and maintained at –80°C until use. Thawed fecal slurry (200 mg feces) was suspended in 2 ml M9 minimal medium, with vigorous mixing to homogenize sample and break any clumps. The fecal slurry was centrifuged at low speed to eliminate large particulate matter and then at high speed for 2 minutes to harvest cells. Cells were then washed twice with M9, filtered through a 35-μm cell strainer, and diluted 1:100 in enrichment media (brain heart infusion [BHI] media supplemented with 500 μM l-carnitine). Cultures were grown under anaerobic conditions at 37°C for 12 days, diluting 1:100 in enrichment media every 2 days. After 12 days in culture, enriched communities were spread and plated in BHI plates supplemented with 500 μM l-carnitine. To reduce the complexity of the microbial community, single colonies, groups of 2–3 colonies, and groups of 4+ colonies totaling 768 cultures were then picked and inoculated into 1 ml of BHI containing 50 μM d9-l-carnitine. After 24 hours at 37°C under anaerobic conditions, a sample of culture supernatant was collected and quenched by addition of formic acid to a final concentration of 0.1%. The amount of d9-TMA produced was determined by LC-MS/MS. The top d9-TMA–producing well was selected and replated, repeating the community simplification steps as described above. Once the top d9-TMA–producing community was identified, the cells were spread and plated. Single colonies were isolated and identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) using a Biotyper System (Bruker Daltonics Inc.) (64). Isolates with similar high-confidence identification were pooled into 4 separate species pools, SP1 through SP4. All isolates with no reliable identification by MS were pooled into a fifth pool, SP5, and subsequently identified by 16S-rRNA sequence analysis (AccuGENX-ID, Accugenix).
Single microbial isolates or pools of isolates were evaluated alone or in combination for their ability to catabolize compounds of the l-carnitine pathway. Starter cultures were grown in BHI for 24 hours at 37°C under anaerobic conditions. Cells were harvested by centrifugation and washed in M9 minimal medium. After washing, cells were resuspended in M9 supplemented with 50 μM d9-l-carnitine or 50 μM d9-γBB as indicated. For kinetic experiments with fecal communities, fecal slurries prepared as described above were used instead of starter cultures. Reactions were allowed to proceed for up to 32 hours at 37°C under anaerobic conditions, as indicated. Samples of culture supernatant quenched by addition of formic acid to a final concentration of 0.1% were analyzed by LC-MS/MS to quantify concentrations of d9-TMA, d9-l-carnitine, and/or d9-γBB.
Human fecal polymicrobial incubation with deuterium-labeled l-carnitine and γBB. Human fecal samples were collected, snap-frozen in glycerol stock using liquid nitrogen, and maintained at –80°C until use. Feces (50 mg) was incubated with 1 ml reaction solution containing 150 mM d3-l-carnitine, d9-l-carnitine, or d9-γBB as indicated within 10 mM HEPES, pH 7.4, in a gas-tight reaction vial under anaerobic (Argon) conditions at 37°C. Reactions were stopped 16 hours later by addition of formic acid to a final concentration of 0.1%. The products were determined by LC-MS/MS with d4-choline and 13C3,15N-TMA added as internal standards and normalized to mass of fecal content.
General statistics. A Mann-Whitney (Wilcoxon rank sum test) 2-tailed nonparametric test or a Pearson χ2 test was used to compare group means and AUCs. A Wilcoxon matched-pairs test or a zero-inflated linear mixed-effects model was used to assess linked human and baseline treatment effects as deemed appropriate. A repeated-measures 1-way ANOVA test was used to assess differences of baseline plasma concentrations of γBB and TMAO between multiple visits. For all analyses a P value less than 0.05 was considered significant. All data were analyzed using R software version 3.43, JMP version 14, or Prism (GraphPad Software).
Study approval. All clinical investigations were conducted according to Declaration of Helsinki principles. All research subject gave written information consent prior to inclusion in the study, and all human studies were approved by the Cleveland Clinic institutional review board. Participant samples were identified by code number only.
RAK helped conceive, design, perform, and organize many of the experiments, assisted in statistical analyses, and assisted in drafting of the manuscript. BRLG conducted microbial isolation and characterization experiments. ZW assisted with mass spectrometry and human fecal polymicrobial culture enzyme assays. BSL, DB, and XG synthesized and purified all heavy isotope–labeled compounds used in the studies. MFC and DBC performed kinetics polymicrobial studies. JK helped in recruitment and performance of the human l-carnitine and γBB challenge studies. HJD, EBB, XSL, XF, and MKC assisted with mass spectrometry analyses. YW and LL performed statistical analyses. JAD helped with study design. WHWT helped with human studies design and oversight. JCGG conceived and designed microbial isolation and characterization studies and helped draft the manuscript. SLH conceived the idea, helped design experiments, and helped draft the manuscript. All authors participated in critical review of the manuscript.
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We thank L. Kerchenski and C. Stevenson for assistance in performing the clinical studies, and A. Pratt, S. Neale, M. Pepoy, B. Sullivan, and K. Ward for technical assistance with human specimen processing and routine clinical diagnostic testing. We thank the Cleveland Clinic Cardiology Fellowship Program for providing support from the Ralph C. Wilson Jr. Fellow Leadership Education endowment to RAK, and the Leonard Krieger Endowed Chair fund for partial support of SLH. Mass spectrometry studies were performed on instruments supported in part by a Center of Excellence Award by Shimadzu Inc. This work received funding from National Institutes of Health and Office of Dietary Supplements grants HL103866, HL126827 and DK106000, and the Leducq Foundation.
DB’s present address is: Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota, USA.
MKC’s present address is: Department of Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Conflict of interest: ZW, BSL, and SLH are named as co-inventors on pending and issued patents held by the Cleveland Clinic relating to cardiovascular diagnostics and therapeutics, and have the right to receive royalty payment for inventions or discoveries related to cardiovascular diagnostics or therapeutics from Cleveland HeartLab, Quest Diagnostics, and Procter & Gamble. SLH also reports having been paid as a consultant by Procter & Gamble, and having received research funds from Procter & Gamble and Roche. BRLG, MFC, DBC, HJD, and JCGG are employees of Procter & Gamble and are named as co-inventors on patents relevant to this work.
License: Copyright 2019, American Society for Clinical Investigation.
Reference information: J Clin Invest. 2019;129(1):373–387. https://doi.org/10.1172/JCI94601.
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Heianza Y, Ma W, Manson JE, Rexrode KM, Qi L. Gut microbiota metabolites and risk of major adverse cardiovascular disease events and death: a systematic review and meta-analysis of prospective studies. J Am Heart Assoc. 2017;6(7):e004947.
Barnett C, et al. Effect of L-carnitine supplementation on muscle and blood carnitine content and lactate accumulation during high-intensity sprint cycling. Int J Sport Nutr. 1994;4(3):280–288.
Trappe SW, Costill DL, Goodpaster B, Vukovich MD, Fink WJ. The effects of L-carnitine supplementation on performance during interval swimming. Int J Sports Med. 1994;15(4):181–185.
Vukovich MD, Costill DL, Fink WJ. Carnitine supplementation: effect on muscle carnitine and glycogen content during exercise. Med Sci Sports Exerc. 1994;26(9):1122–1129.
Orer GE, Guzel NA. The effects of acute L-carnitine supplementation on endurance performance of athletes. J Strength Cond Res. 2014;28(2):514–519.
Wall BT, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol (Lond). 2011;589(pt 4):963–973.
Decombaz J, Deriaz O, Acheson K, Gmuender B, Jequier E. Effect of L-carnitine on submaximal exercise metabolism after depletion of muscle glycogen. Med Sci Sports Exerc. 1993;25(6):733–740.
Pekala J, et al. L-carnitine — metabolic functions and meaning in humans life. Curr Drug Metab. 2011;12(7):667–678.
Demarquoy J. Radioisotopic determination of l-carnitine content in foods commonly eaten in Western countries. Food Chem. 2004;86(1):137–142.
Rigault C, Mazué F, Bernard A, Demarquoy J, Le Borgne F. Changes in l-carnitine content of fish and meat during domestic cooking. Meat Sci. 2008;78(3):331–335.
Lo WK, et al. Comparison of inverse and regular 2-pyridyl-1,2,3-triazole “click” complexes: structures, stability, electrochemical, and photophysical properties. Inorg Chem. 2015;54(4):1572–1587.
Morgun A, et al. Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks. Gut. 2015;64(11):1732–1743.
Wang Z, et al. Protein carbamylation links inflammation, smoking, uremia and atherogenesis. Nat Med. 2007;13(10):1176–1184.
Gandour RD, Colucci WJ, Stelly TC, Brady PS, Brady LJ. Active-site probes of carnitine acyltransferases. Inhibition of carnitine acetyltransferase by hemiacetylcarnitinium, a reaction intermediate analogue. Biochem Biophys Res Commun. 1986;138(2):735–741.
Colucci WJ, Turnbull SP, Gandour RD. Preparation of crystalline sodium norcarnitine: an easily handled precursor for the preparation of carnitine analogs and radiolabeled carnitine. Anal Biochem. 1987;162(2):459–462.
Chen FCM, Benoiton NL. A new method of quaternizing amines and its use in amino acid and peptide chemistry. Can J Chem. 1976;54(20):3310–3311.
Morano C, Zhang X, Fricker LD. Multiple isotopic labels for quantitative mass spectrometry. Anal Chem. 2008;80(23):9298–9309.
Seng P, et al. Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Infect Dis. 2009;49(4):543–551.
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Gut mediated atherogenicity of L-carnitine: is there something missing?
Mario Bonomini
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DOMINICAN REPUBLIC – TABACALERA A. FUENTE
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Let’s Plan a Trip
How to have An Active Vacation in Croatia: BIKING
July 3, 2015 /in Active, Adventure, Brac, Croatia, Croatia, Destinations, Dol, Hvar, Live Like a Local, Motovun, Postira, Skrip, Split, Tour, Videos /by Kelley
My trip to Croatia with VBT Bicycling & Walking Vacations allowed me to enjoy all the joys of traveling, while being active at the same time. There are few things more gratifying than being your own transportation and gliding a bike over hills and valleys on the stunning Dalmatian Islands is hard to beat.
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Meeting the Locals in Croatia
October 2, 2014 /in Brac, Croatia, Croatia, Destinations, Dol, Europe, Hvar, Live Like a Local, Local Travel, Motovun, Postira, Skrip, Split, Tour, Videos /by Kelley
Croatia is fertile–it’s countryside is ripe with fruits, vegetables, grapes and olives, it’s forest filled with wild game and truffles and its seas teeming with the freshest fish. The islands boast stone used to build the palaces of the royals. Enjoy the local delights of Croatia with me.
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Croatia’s Local, Natural Products
October 2, 2014 /in Beer, Wine & Cocktails, Brac, Croatia, Croatia, Culture, Destinations, Dol, Food, Hvar, Live Like a Local, Motovun, Postira, Skrip, Split, Tour, Travel Guide, Videos /by Kelley
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Exploring Croatia By Bike, Boat & Foot
October 2, 2014 /in Active, Adventure, Brac, Croatia, Croatia, Destinations, Dol, Europe, Hvar, Live Like a Local, Local Travel, Motovun, Postira, Skrip, Split, Tour, Travel Guide, Videos /by Kelley
By bike, by foot, by boat or by car, there’s so much to explore in Croatia. Join me in our Croatia adventure
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Upper School Club Supports Girls in STEM
When Dr. Harrington connected Upper School science teacher Mary Fran Park with a visiting Head of School from Greenwich, Connecticut last year, it was a serendipitous encounter. It was then that Ms. Park learned of the GAINS Network, founded by Ann Decker at Greenwich Academy. The Girls Advancing in STEM (GAINS) initiative supports high school girls' interest in science, technology, engineering and mathematics (STEM) and connects them with like-minded peers and role models. "The reason I have gone back to graduate school has everything to do with this topic," says Ms. Park, who is currently midway through her doctorate in Entrepreneurial Leadership in Education with a focus on reducing the gender gap in STEM at the high school level.
Ms. Park and Upper School science teacher Emily Danitz, both passionate about science education, had different experiences growing up. Ms. Park had no female role models in science, and credits stubbornness to her success; whereas Ms. Danitz grew up with strong women mentors—her mother and sister—with careers in science. Both, however, noticed that the higher they went in education, the fewer women they encountered. This is often referred to as the "leaky pipeline," in which women become underrepresented in the STEM fields. Hoping to shift that trend for the students they teach, they proposed the idea of a KDS GAINS club to Dorothy '21 and Alix '22, two students who are also passionate about girls in STEM. Their excited response was, "let's do this!", and Kent Denver became the first high school in the western region to join the GAINS Network.
Open to all types of high schools across the country, the GAINS Network provides themed, monthly webinar curricula that high school clubs can tap into, and an annual national conference for girls to network and learn from peers and professional women. In chemistry-themed October, they featured a cosmetics chemist, Jasmine Johnson, who, when she was in college, had no mentors who even knew how she could enter that field. As a Black woman, she took on internships, networked and blazed her own trail in developing cosmetics for darker skin.
November was conference month, and seven Kent Denver students attended the medicine-themed GAINS 2020 conference virtually with Ms. Danitz. "Having the opportunity to listen to and interact with really accomplished female scientists who are leaders in their fields was incredible," says Ms. Danitz. "Our students made some important connections and were truly inspired by them. I personally connected with a Ph.D. student at Yale doing really cool research on drinking water contamination, who now plans to virtually 'visit' my chemistry classes in the spring. What a cool resource!"
The GAINS club at Kent Denver meets twice a month, and is designed to empower girls to pursue their interests, and introduce them to the many different careers available in STEM fields. There are currently about 15 girls in the club who attend regularly, and members are welcome to drop in on their topics of interest, and take it in whatever direction they wish.
Another long-term goal of the Kent Denver GAINS club is to curate an alumni mentor network of women in STEM, for girls to tap into for independent studies and their senior Career Intern Experience (CIE). For computer science-themed December, the KDS GAINS club held a virtual panel with four alumni, arranged with the help of Elyse Rudolph, Director of Alumni Programs and Special Events. "Liz Beaver '13, Kelli Frank '15, Lena Rutherford '15, Leah Hardy '94 and our very own Rollins Institute for Technology and Design resident Katherine Schneider captivated our meeting and talked all about women and computer science and tech," says Ms. Park. "We had a fantastic turnout." Next week, the GAINS Network curriculum will feature a woman computer scientist.
"The science department at Kent Denver is looking really deeply at how we can support girls to take STEM electives—especially in computer science, physics and engineering—fields with documented gender gaps, both nationally and here at Kent Denver," says Ms. Park. Under the umbrella of Kent Denver's EmpowHERment program, the vision for the Upper School GAINS club is to welcome and encourage all girls who are interested to take a deeper dive into the many rich and fulfilling careers in STEM fields, while being supported by and networking with fellow girls and women.
More Kent Denver News
KDS Reflects on MLK and the Racial Justice Movement in America
Summer Registration Now Open!
Financial Aid: An Investment in Our Community
Sun Devil Social Media
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COVID-19 – UK ISPs Being Urged to Offer Free Broadband
Friday, March 20th, 2020 (7:46 am) - Score 9,066
The Government is understood to be in “very early talks” with UK internet access providers over how they could better support people during the COVID-19 (Coronavirus) crisis, which has resulted in many people and families needing to work from and stay at home. One option could be to offer free broadband.
At present some providers, such as KCOM and BT, already have special social tariffs for those on state benefits, which are cheaper but also slower and often only come with very meagre data allowances (e.g. 15GB on BT Basic with a 10Mbps average speed [ADSL2+] for £9.95 a month with line rental). For other providers the social tariff may also only cover a phone service, although most other ISPs don’t offer such a tariff at all.
However the BBC reports that the UK Internet Service Providers Association (ISPA) is in early talks with the Government about the possibility of introducing additional support measures during the COVID-19 outbreak, which at least one head teacher has suggested could ideally include giving consumers free broadband. But it is presently unclear what has actually been discussed with ISPs.
Implementing free access across such a large and diverse array of broadband ISPs, connection types and packages would be difficult, especially for smaller providers that may struggle to survive, but is possible. Nevertheless ISPs will no doubt argue that it may be unsustainable for them to offer a free service for very long, particularly if their suppliers (e.g. Openreach, BTWholesale etc.) still continue to charge them.
A Spokesperson for the ISPA said:
“Things are naturally developing extremely quickly at the moment, and ISPA plans to seek further guidance from government on these issues so that customers can remain connected to the internet during these unprecedented times.”
Realistically it seems unlikely that the Government would mandate that every ISP offer free broadband for all (too many providers would be at risk of collapse) and thus any agreement seems almost certain to be voluntary, most likely focusing upon the largest providers.
On the other hand such measures could be more strategically targeted at vulnerable groups, such as those covered by the aforementioned social tariffs (e.g. unemployed people or those in receipt of other essential state benefits), and will probably be time limited until COVID-19 is resolved. But that is merely speculation on our part and it could also just result in a series of general discounts or included extras being offered.
We note that some providers, such as Virgin Mobile (Virgin Media) and Sky (Sky Broadband), have already provided customers with a few free extras and allowance boosts – mostly related to voice calls and mobile rather than broadband – to help them (here and here). Judging by today’s news, we should expect further changes to follow.
Finally, some people will probably recall that the UK Labour Party attracted a lot of criticism last year for their populist idea of nationalising the entire broadband industry and giving everybody free full fibre access (here and here). But that was radically different from what is being discussed above and would have taken years to implement (not to mention causing huge industry disruption etc.).
Tags: Politics
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COVID-19 – ISP BT (EE) UK Offers Extra Support to Customers »
I do think one thing that may come out of Covid may be that 111 or similar NHS site might become a mandatory connection on phones etc (ie free data/connection) in the manner 999 is for calls.
andrew cunningham says:
The Americans have implemented such a thing already via many cable companies to families who have students of all ages at home without service via a temporary free service.
Ferrocene Cloud says:
It’s nice that some random head teacher with no knowledge of the industry or SP networks thinks it should be free, but capacity, hardware, and trained engineers to implement and fix cost money. Perhaps they should remember that not everyone has a guaranteed public sector job. Somehow I imagine that if this person was told they should work for free they would quickly sing a different song.
It would make far more sense for the government arrange with providers to pay for services to be sold at-cost. Something like 10Mbps is more than enough for basic connectivity. And less likely to get the capacity planning team worried.
125us says:
I think there’s a reasonable argument to be had that all the people who are losing their jobs as we speak should be able to retain connectivity even if they won’t be able to pay their bills. The government can only manage this crisis if they’re able to communicate with folks.
I agree with you when it comes to providing new services, but the argument is different for existing. The marginal cost of continuing to provide an existing service is fairly small. It would come with a big revenue impact for service providers and especially Openreach but that’s one of the business costs of providing essential public services. It will need government action to stop SPs trying to gain advantage though, I think they’ll all have to do it.
I agree with offering help to those who are struggling to pay the bills, but there are multiple options there. That certainly wasn’t my interpretation of the “just make it all free” sentiment.
Jake4 says:
Would be good if Openreach & BT to provide symmetric speeds for FTTP customers to allow people to work at home easier.
I’ve had several long-ish periods of being a permanent homeworker in my career and I haven’t felt the need for symmetry. Standard broadband is perfectly fine for working with smaller files, telephony, video conferencing and email.
During the times when I’ve worked with very large files (Mainframe system analyst and GIS development) I’ve worked with those files on remote machines. You don’t need to upload and download huge files to be able to work with them and in fact many organisations’ security policies would prohibit it anyway.
Probably moot anyway because there is absolutely no way of flicking a switch and making asymmetric connections suddenly symmetric.
wireless pacman says:
Free food from supermarkets
Free fuel from filling stations
Free beer from pubs (hmmm…. …nice!)
Meadmodj says:
Most people already have sufficient access to sufficient bandwidth for essential home working or home tuition. Plan the day.
In addition many with either personal or business Smart phones in 4G areas can use tethering as an alternative or in addition.
If there is an issue it will be for those with very slow ADSL and no 4G.
You certainly don’t have an issue if you already have Ultra and providers cabnt simply reconfigure their networks even if it was technically possible.
More practical solutions would be
Opening community or empty business facilities that have decent broadband with WIFI and desks (socially isolated distance).
Granting temporary access to your neighbours to your WIFI (or via guest AP) if they have no broadband or limited broadband
ISPs allowing temporary free access to Public WIFI (including VM, BT FON etc)
Every BT residential router has the BT with Fon service so why not have BT make the BT with Fon service free for vulnerable people so they can piggyback on existing capacity without setting up new lines or compromising security.
Where I live, there are a lot of residential Fon hotspots (including one from my router) due to the proliferation of BT fibre service.
Kate Green says:
I think digital poverty is the key issue. Education is not a level playing field as it is. I teach some people who purely rely on mobile data and therefore cannot access online learning in the same way that some of their peers can. For a certain amount of time, with government intervention, education/wi-fi/ a broadband connection needs to be made accessible to all – of course this will be at a cost but a lot of costs are being shouldered by the government (and ultimately the tax payer) and the cost of education throughout the summer term – for all – needs to be factored in at this tough time.
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PL, PFA & EFL ANNOUNCE BAME COACH PLACEMENT SCHEME
New scheme open to BAME PFA members at any age or stage in their careers who would like to transition into coaching in the professional game
The Premier League, PFA and EFL have today launched a new coach placement scheme aimed at increasing the number of Black, Asian and minority ethnic (BAME) players transitioning into full-time coaching roles in the professional game.
The BAME player-to-coach placement scheme, open to BAME PFA members at any age or stage in their careers, will provide up to six coaches per season with a 23-month intensive work placement within EFL clubs. It is jointly funded by the Premier League and the PFA with bursaries provided to each participant via the placement club.
The first intake will run as a pilot scheme, either in the club’s Academy or First Team environment, beginning at the start of Season 2020/21.
Each coach will participate in an individualised learning and development programme. Participants will work across a variety of football functions within the club to broaden their learning experience. This could include the coaching of different age groups, physical performance and conditioning, recruitment, analysis and administration.
Participants will also receive mentoring from the PFA’s Coaching team, comprising 14 former players turned Elite Coach Educators, who have extensive experience in developing coaches within a club environment. Members of the Premier League’s Black Participants’ Advisory Group, which includes experienced coaches Darren Moore and Paul Nevin, have also offered their support to the players and clubs involved in this programme.
Supported by The FA, this scheme has been developed over the last 18 months and complements the Premier League’s existing BAME coach development programme, which launched in 2015. The Premier League Elite Coach Apprenticeship Scheme provides a bursary for eight BAME and female coaches per intake and sees participants placed in Premier League and Category One Academies.
Premier League Chief Executive Richard Masters said: “It is vital that there are no barriers to entry to the pipelines for employment in coaching. We need more BAME coaches entering the system to create greater opportunities throughout the professional game.
“This new programme has been developed through collaboration and consultation with our colleagues across football. We have taken what we have learned from running the Premier League Elite Coach Apprenticeship Scheme and applied that experience to develop this framework.
“We welcome the support from our Black Participants’ Advisory Group and the PFA Coaching team, their experience and knowledge will undoubtedly provide meaningful mentorship to those involved in the programme. We hope this scheme will create clear pathways and substantially improve future employment prospects for BAME coaches.”
PFA Chief Executive Gordon Taylor said: “The PFA is proud to support a diverse membership on the pitch, and we are determined to ensure this also translates to substantial BAME representation in all other areas of the game.
“We have designed this collaborative bursary scheme so that talented future coaches amongst our membership can flourish within a structured coaching environment, which includes meaningful pathways for future employment.
“We are also providing candidates with the full support of our Coaching team, who have helped many players transition into management over the last 30 years, including current managers Darren Moore, Frank Lampard and Mikel Arteta.”
EFL CEO, David Baldwin, said: “It is imperative that the appropriate pathways are in place to provide BAME representatives with the opportunities to make the transition from playing to coaching.
“We know the game needs to do more to ensure the diversity and inclusivity we see on the pitch week in, week out, leads to better representation in coaching and managing if we are to embed significant change for the future.
“I am pleased that this project has been developed collaboratively with our colleagues across football, and hope that we can provide an important opportunity for candidates to develop their expertise and experience at EFL Clubs to support the transition into full-time roles in the professional game.”
Darren Moore, Chair of the Premier League’s Black Participants’ Advisory Group said:
“This is a critical time for Black, Asian and Minority Ethnic coaches. We all know and agree that the diversity of coaches and managers must increase and this placement scheme represents a positive step.
“There are lots of roles in the Academy system all the way through to First Team and young coaches can slot in at different points to begin that journey. We need to have the right structures and people in place to develop their careers.
“I know from my own experiences the value of strong support throughout the coaching journey, which is why I, alongside other senior coaches and former players, will be drawing on our collective expertise to provide guidance to those making the transition into coaching and working in the professional environment.”
BLUES HOST EFL TEAM TALK INITIATIVE
Now more than ever, it's important to stay connected
WALKING APART, MOVING TOGETHER
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EDDIE IZZARD'S RUN FOR HOPE
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ONCE A BLUE, ALWAYS A BLUE
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In This Together: Addressing COVID-19
Learn what Itron is doing to support our customers and employees in this latest blog from our CEO.
The utility industry is built on the reputation of consistently being there for our communities, especially in the most critical times. During the COVID-19 pandemic, Itron remains committed to delivering the highest level of support and service to our customers and partners while balancing employee safety and adhering to local and country-level mandates.
We are thankful for all of the essential workers on the front lines every day. We are in this together, and we are here to help.
Recent COVID-19 Blogs
Here for You: Itron Global Customer Support Services through COVID-19
June 18 Update: Latest Trends in Estimated Load Impacts of COVID-19 Mitigation Policies
Delivering Critical Water Service through COVID-19
In This Together: An Update on Itron, Our Customers and COVID-19
Click here to view all blogs related to the COVID-19 pandemic
SALUTING OUR CUSTOMERS
Utilities and cities are delivering safe, reliable service during this pandemic, while continuing to give back to their communities. Here are just a few examples of our customers in action.
Based in Spokane County in Washington state, where Itron is also headquartered, Avista Utilities provides electricity to nearly 340,000 customers and natural gas to about 300,000 customers across 30,000 square miles and four northwestern states. In addition to suspending all collection activity and disconnects for customers, Avista will provide more than $560,000 to help those in need.
Con Edison
Con Edison’s electric, gas, and steam service provides energy for the 10 million people who live in New York City and Westchester County, which have been hit particularly hard by COVID-19. To help set up a drive-through COVID-19 testing facility, Con Edison added more power to a Coney Island parking lot.
Elektro is among the largest electricity distributors in Brazil, serving 228 cities in São Paulo and Grosso do Sul. Amidst COVID-19, Elektro is collecting donations for Transforma Brasil, a non-governmental organization. The donations will be used to assemble 125,000 baskets of goods and hygiene kits to deliver to families in need.
Expect the Unexpected: 2020's Lessons in Innovation & Continuity
Learn how innovation helped evolve the utility industry response to the pandemic, directly from members of our conference advisory board—and hear how the pandemic has either accelerated or paused certain initiatives, programs and areas of focus. Then hear how these organizations are looking beyond COVID-19 to understand where the most significant innovations are taking place in the industry.
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Learn how our technology and services help you operate remotely during this time.
AMI Operations Management
Enhance operational efficiency and deliver the functional capabilities needed to more efficiently manage and operate your AMI system at scale—remotely and efficiently, during COVID-19 and after. Reduce site visits during this time of social distancing and stay-at-home orders.
Even with many employees transitioned to a remote work model during COVID-19, delivering reliable service is still critical to your community—now more than ever. From base-level SaaS hosting to completely managing your software and network, Itron can accommodate virtually any combination of managed services to fit your needs.
The COVID-19 pandemic has had unprecedented impacts on load, making accurate near-term forecasts a challenge. Learn how Itron's forecasting team can help you best model the sudden load shifts due to the various COVID-19 stay-at-home mandates, transition to remote working and more.
Bridge the digital divide and power digital signage to provide residents, visitors and businesses with instant information about transit, traffic and community news—including the possibility for real-time updates about ongoing stay-at-home orders and other COVID-19 notifications.
COVID-19 is Changing Power Consumption
As millions of U.S. residents stay home due to COVID-19, residential electrical consumption is on the rise and power companies are utilizing smart meters to respond to the changing usage patterns in real time.
Enabling Distanced Learning
Learn how Itron is raising awareness about energy and water issues, inspiring innovation and shaping the future through education.
Itron and Discovery Education partnered to create an educational program designed to empower and inspire middle school students to explore the relationship between water and energy—all through the lens of conservation.
Did you know? It takes more water than electricity to turn on a light bulb.
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We partnered with Dr. Michael E. Webber—a globally recognized energy-water expert, author and educator—to create an interactive, digital K-12 STEM curriculum that teaches key concepts about energy, water and conservation to inspire innovation to create a more resourceful world.
To learn more about how we're addressing COVID-19, visit this page—we'll keep it updated with the latest information we have.
If you have specific customer or partner inquiries, please contact your sales or partner representative. For media inquiries, email PR@Itron.com, and for investor relations inquiries, email investors@itron.com.
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Equestrian Success for Students
Students from all year groups have been competing recently in various equestrian events, please see the following reports celebrating their achievements.
British Dressage Championships
Year 9 students, April Lomas, Molly Brock, Talitha Wilkinson and Izzy Pengelly attended the
David Broome Event Centre in Wales, competing for three days between the 12-14 October in the British Dressage Championships.
All four girls qualified in July for the Championships at their local riding school.
The weather couldn’t have been any worse with rain and strong winds reaching up to 50 mph. April, riding Bonnie, came away with a 4th, 5th, 6th and 9th. Molly, riding Shammy, came away with a 7th, 2 x 8th and 2 x 9th. Talitha came away with 5 x 13th on her pony, Molly.
Well done to all the girls for competing in what was a successful weekend.
Equestrian Team Success at Bicton Arena
The Ivybridge Community College Equestrian Team had a successful autumn term competing in the National Schools Equestrian Association (NSEA) Dressage, Showjumping and Arena Eventing Competitions at Bicton Arena, Exeter.
Year 11 student, Rebecca Reid, and her horse Rico won the Arena Eventing Individual Competition at Bicton Arena in October, which was an exceptional achievement in a strong class of 60 riders from schools across the South West. This gave them a qualifying place to the National Championships at Keysoe Equestrian Centre in Bedfordshire. They also qualified individually in Dressage for the Championships. Congratulations to Rebecca for competing at the Championships in both the Arena Eventing and Dressage. They scored 70% in the Dressage to finish 16th and had a great round in the Arena Eventing where they finished just outside the Top 20 in the country.
In the regional qualifying competitions at Bicton Arena, the Dressage Teams performed well, with the Ivybridge Teams finishing in 3rd, 4th and 5th place. Well done to all the Dressage riders especially to Year 7 students Abigail Johns and Eleanor, and Year 8 student Ellie Mackaness, who were competing in the College Team for the first time. Molly Northmore, in Year 11, won the Elementary Class competing as an Individual.
In the Showjumping competition the team finished in 7th place qualifying them for the School’s Plate competition. The Arena Eventing was the final competition and is always very competitive due to the popular format of a round of show jumps followed by a round of cross-county fences. The riders are judged on their style, jumping performance and speed. Congratulations to Katie Reid who finished in 8th place and Courtney Fletcher, in Year 9, who was 15th in their individual classes. This is a fantastic achievement as there were over 50 riders competing in each class.
Jake and Razorlite selected to compete on the England Team
Year 10 student, Jake Myers has had a very busy half term indeed! The first weekend was at Addington Manor, Buckinghamshire with his new young six year old horse, Calcourt Qualvados, where he qualified for the Winter Novice final at Royal International at Hickstead. This was competing against seniors and only his 3rd competition with this horse. There were just two qualifying places and Jake took 2nd place to qualify. They look set to have a promising future together.
Later in the week Jake travelled to the English Home Ponies International at Southview, Cheshire, where he had a fantastic show winning two classes and being selected to compete on the England Team with Razorlite, his 148cm pony. Jake and Razorlite jumped three superb rounds and the team finished in Bronze position.
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Just Walking By
"MIAMI HEAT"
Cameron Russell and Malaika Firth by Mario Testino for VOGUE PARIS, APRIL 2014 in "MIAMI HEAT". Emmanuelle Alt styles Cameron and Malaika in ANTHONY VACCARELLO, ISABEL MARANT, CÉLINE, AURÉLIE BIDERMANN, WOLFORD, GUCCI, AGENT PROVOCATEUR, LANVIN, ASHISH, EMPORIO ARMANI, KILIWATCH, DOLCE & GABBANA BEACHWEAR, JIMMY CHOO, VERSACE, BLK DNM, MIU MIU, POLO RALPH LAUREN, JEAN-CLAUDE JITROIS, SAINT LAURENT BY HEDI SLIMANE, MICHAEL KORS, BURBERRY PRORSUM, MARION GODART, LOUIS VUITTON and DIOR.
Photos: Mario Testino for VOGUE PARIS via City Girl Diaries and Visual Optimism
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Ribble Valley Walks
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Sabbat - Pendle Witch Trial drama returns to The Dukes, Lancaster to mark 400th anniversary
PUBLISHED: 00:49 05 July 2012 | UPDATED: 21:35 20 February 2013
Christine Mackie, who plays Alic Nutter, looks towards Pendle Hill
The 400th anniversary of the Pendle Witch trials heralds the return of a hugely successful stage drama. Louise Bryning reports
Christine, who lives in Lancaster
The print version of this article appeared in the July 2012 issue of Lancashire Life
We can deliver a copy direct to your door order online here
Midway between the castle where the Lancashire Witches were tried and the hilltop where they were executed is a theatre which is telling their story this summer. The Dukes in Lancaster is also next door to the pub in Moor Lane where legend has it the witches had their final drink before facing the gallows.
With Lancasters many connections to the single biggest witchcraft trial in the UK, its little wonder that when The Dukes first staged the play Sabbat in 2009, it enjoyed a recordbreaking run. Three years later, as the county commemorates the 400th anniversary of the witch trials, The Dukes hopes the revival of the human drama behind this historic event will be equally compelling.
Just as in 2009, Sabbat will be staged in The Round at The Dukes, the ultimate intimate theatre experience. But unlike first time around, once its initial nine-day run at the Lancaster theatre has ended, Sabbat will go on tour, taking top class drama to the home towns of many new audiences. The two other Lancashire venues which will be hosting Sabbat are Hoghton Tower and Colne Muni.
Darwen born director Amy Leach
Hoghton Tower has its own connection to the witch trials as it was famously visited by King James I who, when not knighting loins of beef, was busy stamping out witchcraft and even wrote a book on the subject. And the Muni Theatre is right at the heart of Lancashire Witch country.
Sabbat tells a human story set against a climate of fear and superstition. It begins with a secret meeting the Sabbat held high on a hill in Pendle and ends on another hill, in Lancaster, where ten are hanged for witchcraft.
The play imagines the events leading up to the trial and execution of the witches and asks whether Alice Nutter and her other acquaintances really were witches or innocent victims at a time of paranoia.
The story is one very familiar to Sabbats director, Amy Leach, as she hails from Darwen. We used to have two stuffed witches in our hallway! said Amy.
In 2009, Sabbat was Amys directorial debut at The Dukes, the Lancaster theatre she had visited many times as a youngster. Although the original creative team remains the same, there will be two new members of the four-strong cast.
The cast on a visit to Jubilee Tower, built for Queen Victoria’s diamond jubilee
Im really excited about doing Sabbat again and taking it on tour, said Amy. Its amazing what effect being surrounded by that real sense of history has on a play.
Touring Sabbat across Lancashire and then beyond to The New Vic near Stoke and the Orange Tree at Richmond, Surrey, will bring its own challenges for The Dukes production and operations manager, John Newman-Holden.
We want the audience to feel like theyve stepped back into the 17th Century, said John.
The advantage of staging plays in the round is that the audience are no more than three rows away from the action so they feel really involved. Theres nowhere for the actors to hide.
Dukes Theatre is in Moor Lane, where the witches walked to their execution
One of the actors whos used to being up close to her audience is Christine Mackie who will be reviving her role of Alice Nutter, just weeks after filming an episode of Downton Abbey in which shes already appeared twice.
Christine has lived in Lancaster since 1988 so is well aware of the citys connection to the witch trials.
Sabbat is not just an old story or a Lancaster story, its bigger than that. A lot of people across the world believe in witchcraft so its very much current news.
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Irene Josey
Home » Treasurer & Public Trustee » Third Party Resources » Tax Lien Information » Treasurer's Deed
Endorsement of Tax Liens
Tax Lien Redemption
The only person(s) who may apply for a Treasurer's Deed is the holder of the Tax Lien Certificate. For real property only, a Treasurer's Deed may be issued three years from the date of the original sale, upon proper application and notification. For Mobile Homes, a Motor Vehicle Title may be issued one year from the date of the original sale, upon proper application and notification.
Contact the Treasurer's Civil Deputy in charge of Treasurer's Deed and request an application at (970) 498-7029. Or contact her via email.
Please return the completed application, the original tax certificate, (if you are not having it held in safekeeping with our office), and the $350.00 application fee to our office at 200 West Oak St., Suite 2100, Fort Collins, CO 80521.
Per C.R.S. 39-11-120, applications received without the original certificate cannot be processed.
The application fee is a title expense which includes, title commitment and policy, advertising charges, mailing fees, posting fees and any additional charges accrued in procedures by statute for issuance of a Treasurer's Deed.
The Treasurer's Deed process takes approximately five to six months, given no unforeseen problems. The deed is issued four months, (120 days), after the first date of advertising. Advertising is initiated as soon as the title commitment and certified mailing to legally interested parties is complete.
The Treasurer's Deed will be issued if redemption is not made prior to the execution date. The Treasurer's Deed is recorded with the Larimer County Clerk and Recorder.
Current Treasurer's Deed newspaper postings..
The Treasurer's Deed will not be issued until all subsequent property tax liens are paid in full.
A Treasurer's Deed is an unmarketable title for seven years. You may deed the property to another individual; however, you may not warrant the title. Please contact an attorney or title company for further information. The Treasurer's Office is unable to advise you in this matter.
If the certificate is redeemed prior to deed issuance, you will receive your investment, interest, and your application fee in full. However, no interest is earned on the application fee.
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Latent Anxiety
Latent Anxiety, a unique, innovative and award-winning music project from Los Angeles, is the brainchild of Ilja Rosendahl. A songwriter, producer and talented musician, Ilja's thought provoking lyrics sung in different voices, tight guitar riffs and experimental approach are his musical purport into the developments of modern society and the depths of human emotion. He brilliantly creates a refreshing blend of diverse dark wave, industrial and gothic themes with tasteful infusions of rock, pop and dance music featuring mind boggling vocals, grinding intelligent guitars and melodic synths in a multidimensional sound that he calls Electronic Alternative Rock (EAR). Latent Anxiety does not get caught up in one particular musical style or genre, but truly defines its own boundaries while presenting substantial crossover ability and something for every listener.
Considered for Grammy Nomination 2009-2011
Winner of eWorld Music Awards fka Hollywood Music Awards 2011
Nominee of eWorld Music Awards fka Hollywood Music Awards 2010
Winner of Equinox I Music Video & Audio Contest 2009
Multiple Award Winner of Song Of The Year Contest 2005-2009
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Theater Owner Seeks $1M Payout Under 'Pandemic' Clause
By Mike Curley
Sign up for our Commercial Litigation UK newsletter
Law360 (April 6, 2020, 3:50 PM EDT) -- A Texas theater owner is taking a group of underwriters at Lloyd's of London to court after the insurers said they would not pay out on a $1 million policy for shutdowns resulting from COVID-19, claiming the denial flies in the face of a "pandemic event endorsement" in the policy that specifically covers coronavirus-related disease.
SCGM Inc., which owns a group of theaters including Star Cinema Grill and Hollywood Palms Cinema, said in its complaint Friday that it went out of its way to get the endorsement in the policy, and paid a premium for it, because of the "catastrophic" effect a pandemic would have on its business.
According to the complaint, Lloyd's marketed the pandemic event endorsement following the 2014 Ebola outbreak, advertising it as filling the gaps that other insurers wouldn't after other companies created exclusions in their policies to avoid paying out in the event of another outbreak.
But when SCGM contacted Lloyd's after local and state officials ordered business shutdowns and social distancing measures, Lloyd's told the theater chain COVID-19 is not covered under the endorsement because it is not a named disease under the endorsement.
According to the complaint, however, the endorsement specifically lists "mutations or variations" of "Severe Acute Respiratory Syndrome-associated coronavirus [SARS-CoV]" among the pathogens it covers.
The world scientific community has made it clear that the virus causing COVID-19 is a variation of SARS-CoV, sometimes known as SARS-CoV-2, according to the complaint.
SCGM wrote that Lloyd's refusal of coverage is a "knee-jerk reaction" that is unreasonable, and the speed at which it told SCGM the disease isn't covered — only days after SCGM made the request — shows the insurer did not adequately investigate the claim.
"On its face, Lloyd's conduct appears to be nothing more than an attempt to put insureds in a position where they will be forced to accept lowball settlement offers simply from the fear that their insurer will drag out proceedings well past the insured's ability to remain financially viable," SCGM said in the complaint.
Michael A. Hawash of Hawash Cicack & Gaston LLP, representing SCGM, said Monday he believes this is the first suit against Lloyd's over the pandemic event endorsement, but said he expects more to come as other companies seek reimbursement under the endorsement.
He said Lloyd's interpretation — that COVID-19 is not a named disease covered by the policy — is a very narrow view of the clause since it states that it does cover variations on SARS-CoV.
Hawash added he's looking forward to getting the case to a judge to interpret how the policy should be read.
A spokesperson for Lloyd's declined to comment.
Underwriters at Lloyd's have come under fire from a number of policyholders in the weeks since U.S. businesses began closing in efforts to stem the spread of COVID-19.
In Florida federal court last week, Prime Time Sports Grill Inc., which operates Prime Time Sports Bar in Tampa, sued Lloyd's for its denial of coverage after the state governor ordered nonessential businesses to shut down. And in March, Lloyd's was hit with a suit over the COVID-19 shutdown by a restaurant in New Orleans.
SCGM is represented by Michael A. Hawash, Walter J. Cicack, Jeremy Gaston and Jeremy M. Masten of Hawash Cicack & Gaston LLP.
Counsel information for Lloyd's was not available Monday.
The case is SCGM Inc. v. Certain Underwriters at Lloyd's, case number 4:20-cv-01199, in the U.S. District Court for the Southern District of Texas.
--Additional reporting by Jeff Sistrunk. Editing by Janice Carter Brown.
Update: This story has been updated with Lloyd's London's response to a request for comment.
Case Title
SCGM, Inc. et al v. Certain Underwriters at Lloyd's
Nature of Suit
110(Insurance)
Judge David Hittner
Hawash Cicack
Judge Analytics
powered by Lex Machina®
David Hittner
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About usChevron right icon
About LeasePlan Hellas
LeasePlan has been operating in Greece since 2003 and is an 100% subsidiary of LeasePlan Corporation N.V. During our presence in the Greek market, we have devised a dynamic and steady upward course, offering high-quality operating leasing services and innovative solutions that meet our customers' needs. Our mission is to make corporate fleet management and mobility of the drivers easier and provide "any car, anytime, anywhere".
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The LeasePlan Code of Conduct explains how we must approach our business dealings. The Code of Conduct is founded on sound business ethics and respect for stakeholders and society. By setting high standards, we give clients, suppliers and business partners the confidence to work with us.
Our Code of Conduct guides all employees in their efforts to balance the interests of people, the planet and profit. When conducting business for LeasePlan, consultants, contractors, agents and joint venture partners are all expected to observe the same standards of conduct as LeasePlan employees.
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Financial Statement 2018 (only in Greek)
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Obituaries and Guest Books
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Sheldon Funeral Home - Laceyville, PA - Laceyville
Laceyville, PA 18623
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More Obituaries for ROBERT JAYNE
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ROBERT JAYNE
Robert F. Jayne, 78, of Laceyville, passed away peacefully at his home on Nov. 22, 2020. He was the son of the late Jean Allen Jayne (d. July 9, 1974) and Frank Jayne (d. Feb. 2, 1990).
Bob was born June 26, 1942 in Towanda.
Bob grew up in Meshoppen, and served his country in the Vietnam War from 1964 to 1966, and served in the Army Reserves from 1966 to 1970. He owned and operated the Black Walnut Car Wash for many years. He retired from Procter & Gamble in 1997.
After his retirement, he was an avid golfer for many years winning a number of league championships at Tall Pines Golf Course. He enjoyed traveling and visiting new places, NASCAR, and was a car enthusiast always trading cars.
Bob enjoyed spending time with his daughters most of all. He would take Delicia to endless hockey games and concerts growing up. He would always make sure Delania and her friends had pizza and were properly scared while watching scary movies.
Bob absolutely adored his granddaughters always beaming from ear to ear when talking about them. They were his world.
On May 11, 2013, Bob married Susan Pattison Jones, the love of his life. They spent all of their time together and enjoyed shopping, traveling and countless hours of watching the Food Network. Bob was always coming up with new recipes and enjoyed using his smoker and especially sharing his food for his numerous family dinners he hosted.
Bob is survived by his wife, Susan. His daughters: Delaina Jayne (Duane Naugle) and Delicia Brown; step-children: Valarie Johnson and Jonathan Jones; his granddaughters: Meira Naugle, Nadia, Elliana, Abriella, and Aliza Brown; and many step-grandchildren.
A private service will be held at the family's convenience.
In lieu of flowers donations can be made in his memory to the United Mitochondrial Disease foundation at www.umdf.org or 8085 Salisbury Rd. Suite 201, Pittsburgh, PA 15239 in honor of his granddaughter, Abriella (Abbi) Brown.
Arrangements are entrusted with the Sheldon Funeral Home, 459 Main St., Laceyville.
Online condolences may be made at www.SheldonFuneralHomes.com.
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Twitter becoming key referral source for solicitors, says research
Posted by Legal Futures
Twitter: lawyers need to respond quickly to opportunities
There has been a massive increase in people using Twitter to ask for recommendations of professional service providers in the last two years, with solicitors one of the most in demand, according to research conducted for Orange Business.
It claimed that “small businesses are missing a trick if they take their eyes off tweets”, with its research reporting a 663% increase in people using Twitter to ask for recommendations around common professional services. Ten million Britons are on Twitter.
Most in-demand are web designers whose popularity, Orange speculated, may be skewed by the fact like-minded and tech-savvy individuals are more likely to be on Twitter. “However, second on the list are solicitors, who may not be aware of the fees they could be missing out on by not engaging with the public and other businesses via Twitter,” the mobile operator said. They were followed by accountants, architects and copywriters.
Mike Tomlinson, small business marketing director at Orange Business, said: “It is clear from this research that you can’t just rely on posting adverts in the classifieds. Today, Twitter represents a compelling word-of-mouth engine that can deliver significant business opportunities to small businesses across a wide variety of sectors… If professionals do not engage with people on Twitter, they risk losing out.”
Orange, unsurprisingly, said lawyers should use their smartphones to access Twitter on the move so that they did not miss out on what was happening, and also advised that they should be prepared to offer advice on the micro-blogging site. “Professionals need to showcase their expertise and accessibility over Twitter. It’s not about giving away free counsel but showing you know what you’re talking about and sharing information which might spread far and wide. Your words of wisdom will reach far more potential customers than your silence.”
Also, it said lawyers and others need to be quick in responding to tweets and ensure they can demonstrate their “real-world” credentials by making sure users can easily link from their Twitter profile to a website.
Longridge Law says:
Interesting article! It shows that a personal recommendation is still valued, even in the digital age – and also that perhaps some people aren’t as personally informed on certain legal matters as they could be?
Twitter (and Facebook) seem to be an increasingly crucial element in marketing professional services, not just digital ones – we’ve experienced this first hand, with @LongridgeLaw gaining 280+ followers in just three months.
I really struggle to believe this.
If I am a Corporate wanting to conduct a multi-million pound transaction I doubt I would be on Twitter asking for a recommendation.
Perhaps if I had tripped on a chip and needed an ‘Ambulance chaser’ type lawyer I might ask.
I do strongly believe in person recommendation but that doesn’t cover asking some dudes on Twitter
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/ first team
/ 379040 liverpool fc agree deal to sign takumi minamino
NEXT ARTICLE Mohamed Salah: Everybody deserves to be Man of the Match
Liverpool FC agree deal to sign Takumi Minamino
James Carroll @James_Carroll84
Liverpool Football Club can confirm an agreement has been reached with Red Bull Salzburg for the transfer of Takumi Minamino.
Watch: Takumi Minamino's first LFC interview
The Japan international forward will officially become a Reds player on January 1 after he finalised personal terms and passed a medical on Merseyside on Wednesday.
See LFC Retail's special range to mark the signing, including 'Minamino - 18' jerseys
Minamino told Liverpoolfc.com: “It has been a dream, my dream to become a Liverpool player. And I’m so excited that the moment has come true.
“To play in the Premier League was one of my targets. I think this is the top-class league in the world; I was thinking if my career as a footballer progressed smoothly, someday I would be able to play in the Premier League.
“But I never thought I would be able to play in this team and I’m really happy about it. I’m looking forward to it.”
Minamino has faced Liverpool twice this season while lining up for Salzburg in the Champions League group-stage encounters.
Indeed, the 24-year-old was on the scoresheet in the meeting at Anfield in October when he struck to help the Austrian side fight back from three goals down to draw level at 3-3 before Mohamed Salah netted a winner.
More recently, Minamino completed the 90 minutes for Salzburg as the Reds secured a place in the last 16 of the Champions League with a 2-0 victory at Red Bull Arena on December 10.
“From those games I learned this team has such a high level of technique and intensity,” he added.
“Their football is of such a high level and I did feel that they were the champions of the Champions League. Feeling that, it makes me feel even happier that I can play in this team. I’m really happy to be part of that team.
“My target is to win the Premier League and the Champions League, and to make good contributions to the team.”
In moving to Anfield, he brings an end to his five-year spell with Die Mozartstädter, whom he joined from Cerezo Osaka in January 2015.
In total, Minamino made 199 appearances for Salzburg, scoring 64 goals, while he has earned 22 caps for Japan and netted 11 times since making his debut in October 2015.
WIN a signed 'Minamino - 18' LFC shirt
'He's made big steps' - Klopp pleased with Minamino adaptation
Minamino interview | Festive fixtures, Anfield power and 2021 ambitions
How instinct brought Takumi Minamino his first Premier League goal
Three Reds feature during Tuesday's internationals
Internationals: Firmino, Jones and Minamino score in Friday's games
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Andrew Perez, Reporter
Amanda Batchelor, Managing Editor
Published: November 2, 2018, 5:16 pm
Tags: Local, News, Miami-Dade
Buildings in South Florida light up in amber to honor COVID-19 victims
Broward man bragged about role in Capitol siege on social media, feds say
Drug shows promise in treating Alzheimer’s
Body discovered by woman exercising at Scott Park in Miami Gardens
Kevin L. Willis shot in head; car is now missing, police say
MIAMI GARDENS, Fla. – A man's body was discovered Friday morning by a woman who was exercising at Scott Park in Miami Gardens, authorities said.
He was later identified as Kevin L. Willis. Police have ruled his death a homicide.
Willis' relatives showed up to the park shortly after his body was found, distraught as a yellow tarp covered his body at the playground.
"I'm trying -- it's hard, it's tough," one relative said.
Police said the woman was exercising at the park when she noticed a man with an injury to his head around 6:15 a.m.
"She saw that something was not right with the individual, so she went to go and get help," Miami Gardens police spokeswoman Carolyn Frazer said.
Police said Willis was shot in the head.
"He is wearing some type of security uniform. We're not sure if he was on his way to work. We're not sure what he was doing at the time," Frazer said.
Relatives said Willis worked as both a security guard and a bail bondsman.
According to detectives, Willis left his home late Thursday night in his 2007 silver Chrysler 300 with Florida tag KEAD17.
Police said Willis' car has not been found.
No other witnesses have come forward, and police are asking anyone with information to give them a call.
"If you were like the resident who called the police -- maybe going about your normal duties, exercising and may have seen something, heard something in the night, we're asking that you contact the Miami Gardens Police Department," Frazer said.
People can also submit anonymous tips by calling Miami-Dade Crime Stoppers at 305-471-8477.
Copyright 2018 by WPLG Local10.com - All rights reserved.
Andrew Perez is a South Florida native who joined the Local 10 News team in May 2014.
Amanda Batchelor
Amanda Batchelor is the managing editor for Local10.com.
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High-performance, specification-grade LED luminaires
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Since 1923, Sternberg Lighting has maintained its position as a leader in the street lighting industry by combining the vintage look of decoratively styled luminaires with today's demands on sustainability and the latest LED technology. Sternberg Lighting has worked on more than 450,000 installations throughout the United States and Canada.
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Sienna Miller’s sweet-toothed pregnancy cravings
Pregnant Sienna opens up about her pregnancy now she’s into her second trimester
By Kim Hookem
Pregnant actress Sienna Miller has given us a glimpse into how she’s getting on as a mum-to-be. The famously private celeb is now into her second trimester and feeling more confident about revealing details of her pregnancy. She’s previously given only vague comments about how she’s getting on and left it to her sister to confirm the happy news.
“I’m in my second trimester, so I’m I-can-talk-about-it pregnant, even though I’m under strict instructions not to say anything as it would completely defeat the point of everything I’ve tried to achieve in the last eight years,” the 30-year-old explained, adding she’s worked hard to keep her private life private.
Sienna, who’s expecting her first baby with partner Tom Sturridge, 26, was out and about in central London filming a commercial. She wore a floaty white slip dress that revealed a neat little baby bump.
Though trying to keep a low profile, the mum-to-be did reveal that pregnancy has had a positive effect on her. “I feel very grounded, more than ever – it’s a wonderful feeling,” said Sienna.
The star also shared her pregnancy cravings. “All of a sudden, I’ve started to get cravings,” Sienna said – specifically, it’s vanilla ice-cream on top of… yum… brownies! “I usually don’t have a sweet tooth but these tarts I could eat all day long!” she added.
We don’t need pregnancy to give us the thumbs-up to those, Sienna!
Pregnant celebrity weddings
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Five new famous pregnancies?
Ferne McCann and child – family facts
Fearne’s early morning feeding routine kicks in….
Katie Piper, Richard Sutton and children – family facts
Beyonce creates mobile nursery for Blue Ivy ahead of tour
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Indian rupee symbol selected
In a quick follow-up the previously published Indian rupee symbol options, a new mark has been approved by the Indian cabinet.
Gurpreet Singh shows his artwork depicting Uday Kumar’s new graphic symbol for the Indian Rupee.
The design was chosen in a competition won by a teacher at one of the country’s Indian Institutes of Technology. Uday Kumar’s design was chosen from a shortlist of five and he was awarded around £3,500 in prize money. Interestingly, the short-list of five that was in circulation didn’t include the chosen option.
The symbol won’t be printed or embossed on currency notes or coins, but will be included in the Unicode Standard and major scripts of the world to ensure that it’s easily displayed and printed in the media.
The symbol will also distinguish the Indian currency from some other currencies in the region, like those of Pakistan and Nepal — also called rupee.
Among currencies with distinctive identities, only the pound sterling has its symbol printed on the notes.
Reported elsewhere:
#rupee #Talking
Some Euro notes have the Euro symbol printed/included:
http://www.fuertenews.com/images/20071003/euro_notes.jpg
Take a look at 5,10 and 20.
innovasign says:
I really liked the design. there are 3 things to it. Secondly, It shows the front portion of ‘R’. It’s also had the “R” equivalent of hindi script. Third, it also has the stripes of indian flag. Well done!!
‘the short-list of five that was in circulation didn’t include the chosen option’… it does make you wonder what was going on behind the scenes, yes? Hopefully someone will enlighten us.
I’m surprised it looks similar to the one I preferred which was the third to last option from your last post on this. I say that because it doesn’t look like any of the ‘short list’. I like it. Hope it is successful for them.
lunaticg says:
If this symbol doesn’t included in the earlier top 5, how come it can be a winning design?
Victor Zuniga says:
Very shady. But the winning design does look better than the short list there.
Sanskar Shrivastava says:
I am proud that our currency has joined the elite currency club. though it wont be printed or embossed on the currency notes. keyboard will be soon modified. I can’t wait to see that all. India has done really great to project its economical strength
~Sanskar Shrivastava
I bet Gurpreet Singh is happy as Larry. But 1-5 are all pretty similar as is the chosen route.There isn’t a huge amount you can do with something like this. Out of interest, what do the other Rupee symbols look like?
I wonder why the chosen version wasn’t in the list? I would have picked that one also…
Every indian felt proud when govt launched rupee logo. some said it shows simplicity and some said logo is the combination of hindi varnmala and english letter and its true also. personally i felt logo is not the best but good. dont wana any more about logo because those who selected the logo are very intelligent. Am feeling proud now..
chris trueman says:
and is there a symbol esp for baksheesh?
Yogender says:
I love the new Indian rupee logo… AWESOME.
Bindia says:
Update : RTI (Right To Information) had already exposed that he is Non-eligible candidate for Indian Rupee Symbol Design Competition as he had violated the Indian Rupee Symbol Design competition guidelines .
According to guidelines one candidate could send maximum two design entries but he had submitted a total of four designs.
Second violation of guideline is the symbol itself, as it’s not applicable to standard keyboard or Unicode enable.
Violations are not stopping here according to information and broadcasting minister Ambika Soni “The new rupee symbol partially resembles the Devanagri ‘Ra’ and Roman capital ‘R’ without the stem coupled with two parallel lines – in line with Finance Minister Pranab Mukherjee’s vision for a symbol which reflects and captures Indian ethos and culture.”
But using roman script/English alphabet in designing the New Indian rupee symbol is also a violation of guideline according to the guideline “The symbol had to be in the Indian National Language Script”.
But according to National language Script English is not included in that list till this date.
All the above facts clearly show that his candidacy for the Indian rupee symbol competition has violated the guidelines which can be found http://www.saveindianrupeesymbol.org
I think case has also been field against this decision in India court.
Will need to remove the upper dash on the official logo…. it is tough to write the symbol otherwise and also looks ugly when hand written….
Wow what a nice symbol it is awesome symbol..i am proud that we have got such a nice symbol…and hats off to the founder of the symbol.
Thomas Mathew says:
How can we type the symbol of Rupee from Microsoft Word or Pagemaker?
saraswathi says:
The new Indian rupee logo is really very awesome. When it comes to the keyboard, the dollar symbol is modified to India rupee to key word, so very easy use to directly Indian rupee not by any shortcuts.
A srivastava says:
Historical improvement……….
Delhi HC Allows RTI Activist To File PIL Against “Rupee Symbol Selection Process”
source- http://www.saveindianrupeesymbol.org/2011/06/delhi-high-court-allows-rti-activist-to.html
A better level of ‘achievement’ for CIMA
Number 1 in the Official Charts
The kiddie designers of 99designs
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IRGC-led Afghan group holds first ‘international conference’ in Iran
By Amir Toumaj | September 15, 2020 | [email protected] | @AmirToumaj
The Afghan paramilitary group Fatemiyoun Division, which answers to the Islamic Revolutionary Guard Corps (IRGC), held its first “international conference,” an ideological indoctrination gathering, on Aug. 13 at the Imam Reza shrine in Mashhad, Iran.
The Fatemiyoun’s Media Center has released more details and content about the event over the last several weeks, shedding light on the event that also revealed the blurred-out face of its chief commander for the first time.
The Fatemiyoun organized the gathering with the blessing of the Reza Holy Precinct, a multi-billion dollar foundation that oversees the shrine and answers to the Supreme Leader Ayatollah Ali Khamenei.
The conference reflected several trends in the Fatemiyoun’s evolution. It represented Fatemiyoun’s effort to solidify a sense of community among veterans and families of fighters who reside in Iran, efforts to enhance ties with other IRGC-backed elements, and efforts to present itself to the Islamic Republic support base as a worthy group in the mold of Lebanese Hezbollah.
The conference also reflected the evolution of the group’s media arm, which produced a number of professional-looking productions, such as montage videos and infographics about the event, and deployed a “journalist” to interview individuals there. A number of Iranian outlets and newspapers also reported on the event.
The conference came amid questions and speculation about the group’s direction following a draw down in late 2017 after the end of a major offensive in eastern Syria against the Islamic State. The Fatemiyoun continue to deploy to and publicize its presence Syria.
In the conference, the Fatemiyoun and other IRGC-backed groups reiterated the goals of destroying Israel and avenging the death of Qods Force chief Qasem Soleimani, both of which are the ideological goals of the IRGC and the Islamic Republic. These ideals bind the IRGC-backed network into an offensive and aggressive vision – but the realistic ability to fulfill those goals is another matter.
Unnamed commander of the Fatemiyoun Division speaking with a Fatemiyoun journalist. The emblem of the group is displayed on the microphone.
For the first time, the Fatemiyoun displayed its chief commander, though his face was blurred and name was not provided for security reasons. The unnamed commander told a Fatemiyoun Media Center reporter that “all of our effort must be spent on forcing the U.S to leave the region,” which would be the “great revenge” for the U.S. killing Soleimani. It is unclear when he was appointed to this post.
Senior Fatemiyoun commander “Seyyed Elias” addressed the conference and told the Media Center that the conference’s goals were to praise families of martyrs and “create regular conference with tangible result [involving] other countries that are active in the Resistance front,” with the final goals of destroying Israel and expelling the US from the region.
Om-olbanin Hosseini, the wife of deceased Fatemiyoun co-founder and former chief Alireza Tavassoli (“Abu Hamed”), reiterated these goals in a separate interview. Killed in 2015, Tavassoli is the Fatemiyoun’s most recognizable figure, and since his death, Om-olbanin has carried on his legacy and name, giving interviews and appearing in events like the conference.
Fatemiyoun commander “Seyyed Elias”
IRGC-backed paramilitary group representatives and figures addressed the conference through recorded video messages, in which the figures praised the Fatemiyoun, and reiterated their ideological goals of destroying Israel and expelling the U.S. from the region.
Lebanese Hezbollah cultural deputy Hojjat ol-Eslam Akram Barakat said that “anytime I look at the faces of you Fatemyoun mujaheds, I remember the beautiful face of commander martyr Soleimani.”
Iraqi Harakat al-Nujaba spokesman Nisr al-Shimri told the conference that “American forces witness parts of ‘hard revenge’ by your brothers in the Iraqi resistance every day.” He was referring to – and exaggerating – claims of attacks against logistical convoys against Iraqi contractors for the U.S. and related harassment of U.S. forces in Iraq.
Bahrain Islamic Movement leader Sheikh Isa Qasim declared that “Fatemiyoun mujahids have humiliated the Zionist enemy and American pride.”
A Palestinian Islamic Jihad official sent a recorded message in praise of the Fatemiyoun, as well. Iranian cleric Grand Ayatollah Naser Makarem-Shirazi, who is an ally of Supreme Leader Ayatollah Ali Khamenei, also sent a letter in prase of the Afghan group that was read out loud.
Hassan Mughniyeh, the son of prominent Hezbollah commander Emad, was scheduled to speak at the event, but reportedly did not make an appearance.
Advertisement poster for the event, and on top says “subjects are to praise the martyrs of the Fatemiyoun Division, liberation of Jerusalem as the final goal of the Fatemiyoun, and America’s exit from the region.” The conference coincides with Resistance Day in Iran, which is further meant to tie the Fatemiyoun with the IRGC “resistance” project in the region. Displayed speakers are Bahraini cleric Sheikh Isa Qasim and Harakat al-Nujaba official Nisr al Shimri. Poster also advertises two religious singers, known as maddah, who play important roles in retelling the stories of Shiite saints and fallen fighters. Hassan Mughniyeh, son of prominent Hezbollah commander Emad, is “the special guest” of the event, though he did not make an appearance, according to the Fatemiyoun. Featured speakers also include Hezbollah officials, Palestinian “movements” officials, and Fatemiyoun commanders. The event also unveils a book about the Fatemiyoun.
A flag that says “Shrine defender Fatemiyoun Warriors Committee,” which functions as a veterans association group.
A recorded video message by Bahraini Islamic Movement leader Sheikh Isa Qasim.
Example of an infographic produced by the Fatemiyoun Media Center. This one highlights portions of Grand Ayatollah Nasser Makarem-Shirazi’s video message and his praise of the Fatemiyoun.
Iraqi Harakat al-Nujaba spokesman Nisr al Shimri, in a video message, says that Nujaba and Fatemiyoun would fight alongside each other until establishment of the Mahdi government, destruction of Israel, and expulsion of US forces from the region. pic.twitter.com/CrCCNnpQ4S
— Amir Toumaj (@AmirToumaj) August 15, 2020
Amir Toumaj is a independent analyst and contributor to FDD's Long War Journal.
Tags: Harakat al Nujaba, hezbollah, IRGC, IRGC-QF
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The Louisville Cardinal
U of L's Independent Student Newspaper
NewsThe News page is your source for everything you need to know about university administration, the Student Government Association, health, housing and much more!
SportsThe Sports section is your source for all things athletic at U of L. We try our best to cover every game, match and event. Expect nothing less than solid play-by-plays and high-resolution photos of your favorite Cardinals.
FeaturesThe Features section caters to everything you need to know about culture on campus and the Louisville community. Here we explore the arts, student events and the latest trends that make U of L unique.
OpinionThe Opinion section is not only our voice, but yours as well. We encourage U of L students, faculty and staff to use the Cardinal as a soapbox for the issues that are important to you.
PHOTO: RaiseRED raises record-breaking amount for pediatric cancer
February 27, 2016 Roya Fathalizadeh
Photo by Madison Wurth
Photo by Madison Wurth Chester Delph, Sophmore Beta Theta Pi What did you think about the event? “I thought it was an absolute blast. The entire event was phenomenal. They did a great job organizing it.” What was your reaction to the amount of money raised? “It was unbelievable. I was honestly blown away. They had set the bar at $300,000, and we were roughly $75,000 away from it last year, so I was just blown away to find out we reached it.”
Photo by Dustin Massengill
By Roya Fathalizadeh–
Over 900 U of L students raised $322,412.85 for pediatric cancer research at the seventh RaiseRED Dance Marathon this weekend. The amount was close to $100,000 more than what was raised last year, and was $22,000 above the goal of $300,000.
Papa John’s, the RaiseRED presenting sponsor for this year, also threw in $50,000 for the event. Overall, previous RaiseRED records were completely shattered.
The 18-hour event is the only student-run organization to support medical research at U of L. Students host various festivities throughout the school year in efforts to raise money for pediatric cancer and blood disease research, culminating in the no-sitting marathon.
From 6 p.m. to 12 p.m. the next day, close to 1,000 participants joined together, playing games and dancing non-stop. Each dancer had their own story of why they decided to help the cause.
“I did RaiseRED because I wanted to help support cancer research and see a positive impact in the local area,” sophomore AJ Walters said. “I’m really excited.”
Others came back to support the cause again. “This is my second year doing RaiseRED,” junior Michael Hawkins said. “I love playing with the kids and the fact that everyone across campus comes together to support this great cause. Tonight I played dodgeball with Dawson, one of the kids in my group from the clinic. It was just so great to see him just be a normal kid for once and have fun.”
Dancing for 18 hours can seem very tiring. That’s when the RaiseRED morale leaders come in. “I go around and hype people up with games and dances all night long,” morale leader Alex Goranflo said. “I was a dancer last year but this year I wanted to get more involved. I’m a teacher so seeing kids sick makes me really upset and want to make a change.”
Each team dances for a kid with pediatric cancer or a blood disease, and the kids and their families are invited to the event.
“We’ve been coming to raiseRED for several years now and each year I am never failed to be amazed by the amount of support we receive from university students and the rest of the community,” said mother Julie Haise. “We’re here for our six year old daughter tonight, Audrey. She has Diamond Blackfan Anemia, which is a rare blood disease which makes it hard for her to produce new blood cells.”
Audrey has caught the attention of people all across the world with her Youtube videos and smile. She has been featured on The Ellen Show and Good Morning America. Only about 1,000 people in the world are diagnosed with it. There is no permanent cure for DBA.
New families coming to the event for the first time were also happy to see the student involvement in this significant organization. “This is my first year coming to raiseRED and I’m so surprised to see the turnout,” said father Josh Collins. “I’m here for my five year old son Logan tonight. A year and a half ago he was diagnosed with Leukemia, and is in remission now at the clinic that RaiseRED raises money for. I think it’s just amazing what everyone is doing.”
Jake Guhy, a member of Sigma Phi Epsilon Fraternity, served as a Team Leader during this year’s marathon. “I have to give a lot of credit to my fraternity, Sigma Phi Epsilon, but also to the entire Greek community for providing the backbone of support and participation in the dance marathon. Coming together with members of every organization to make a difference has been a great experience,” said Guhy.
“When a child is diagnosed with cancer or a blood disease, their entire world flips upside down. Everything changes,” said Taylor Wilson, who served on the RaiseRED Executive Board. “Mom and Dad now have to get second jobs to afford treatment or quit their jobs to stay with their sick child. Siblings have to spend time with distant relatives while their parents are tending to their child with disease. RaiseRED doesn’t seek to solve the world’s problems or end disease with one dance marathon. Rather, RaiseRED provides hope for families and children affected by disease.”
Tags: 1, dustin massengill, gallery, louisville, madison wurth, michael hawkins, RaiseRed, Roya Fathalizadeh, Top News, Top Story
Previous Tapingo delivery options save students time
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What to expect for Spring 2021
January 18, 2021 Tate Luckey
U of L students prepare for finals week amid pandemic
December 2, 2020 Joseph Garcia
RaiseRED surpasses fundraising goal in their “Week of $20k”
November 24, 2020 Joseph Garcia
Tweets by @TheCardinalNews
Copyright © 2019 All rights reserved. | CoverNews by AF themes.
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Coronavirus: The end of sexist economics?
Tara Davda Priya Chattier
Gender-responsive coronavirus policies are not only smart economics, but provide opportunities to do the right thing.
A nurse takes swabs at a mobile testing site for Covid-19, Melbourne, 30 April (Speed Media/Icon Sportswire via Getty)
Published 6 May 2020 09:00 0 Comments
As coronavirus spreads, government spending, and lots of it, has been the order of the day. Most of the analysis has focused on the economic impact of these responses, with scant attention paid to the impact on gender. Yet the pandemic has exposed the gendered fault lines of the economy, revealing structural inequalities between the sexes. As the debt-GDP ratio grows and fiscal pressure intensifies, has the gendered burden of the economic response been overlooked?
Lavish government spending is typically followed by either “austerity” measures, extensions to debt maturity, or debt default. Australian Treasurer Josh Frydenberg has hinted it will be the second. Even so, political pressure to cut spending in the future will be considerable. Thus, it’s worth considering the impact of this on the more vulnerable members of society.
In this new reality of enforced “home-working”, women face a triple burden: paid work, unpaid care work, and meeting their children’s educational needs.
Although women make a tremendous contribution to the economy, they frequently accumulate lower economic returns than men. This means when gaps in safety nets widen or disappear altogether, women are among the first to fall through, because what can be termed “hyper-Keynesian” economics exacerbates the already constrained fiscal positions of governments. Coronavirus, therefore, is not “gender-neutral”. To ensure that progress on gender equality is not undermined, responses should pay careful attention to this tendency.
This means:
Focusing on the vulnerability of women
Women occupy a disproportionate share of the labour market in sectors vulnerable to this crisis (administration, tourism, or social and community services), and they are more likely to be made redundant under labour market contractions. They comprise one of the lowest paid groups of workers and carry a higher burden of unpaid care work than men. In Australia, they are more likely to occupy low-paid, temporary jobs, making them ineligible for the government’s Job Keeper payment – all factors which render them vulnerable under “austerity”. Women comprise more of the caring profession than men: in Hubei Province, the epicentre of the Chinese outbreak, 90% of nurses dispatched to support the health intervention were women, while globally, women represent 70% of the health and social sectors. Unfortunately, the average gender pay gap is 28% in this sector.
To ensure the full cost of Coronavirus is accounted for, stimulus packages should include social protection measures that seek to retain women’s productive participation in the labour force – for example, with compensatory payments for workers in temporary employment. This would address existing gender inequities in the labour market and reflect an understanding of the obstacles women encounter in the workplace. Such measures are particularly important in the aforementioned “feminised” sectors.
Focusing on the long-term impact of gendered labour division
The impact of coronavirus on labour-market dynamics will have greater consequences for women than men. Faced with unprecedented levels of unemployment, many pre-retirement workers will need to prematurely access retirement savings. At retirement, the superannuation balances of women are 30–40% lower than those of men, suggesting rates of poverty and homelessness are likely to be higher among this group. Gender-responsive social security measures, such as maintaining superannuation payments during maternity leave regardless of employer contributions and reducing fees for those with low balances, should be enacted. This would broaden access to superannuation, making it accessible for disadvantaged women. Without such efforts, social protection measures risk propagating gender inequities introduced in the labour market.
Focusing on the economic impact of the care burden.
Crises aggravate existing gender inequalities because they enact an uneven financial and psychological toll, and because socio-cultural stereotypes mean women are still typically regarded as the primary caregivers in the home, as research from previous epidemics shows. Indeed, women will carry a heavier economic burden over the coming months because, as this commentary argues, “it’s not just about social norms of women performing care roles; it’s also about practicalities (…) Who is paid less? Who has the flexibility [to reduce their hours]?” Other sources support this: in Australia, 64% of the female working week is spent on unpaid care, compared to 36% for men, while globally, women perform ten times the unpaid care work men do.
In this new reality of enforced “home-working”, women face a triple burden: paid work, unpaid care work, and meeting their children’s educational needs, as this spoof of the infamous BBC interviewer interrupted by his children illustrates. To avoid worsening these inequities, governments can support policies that protect women, while employers can “undo” unhelpful gender norms: the flexible work arrangements occurring worldwide should become the “new normal”. This would support family-friendly workplaces on a permanent basis, not just in an emergency.
Addressing the problem
It is essential that gender is prioritised in the response to Covid-19. Progressive fiscal reforms that address existing inequalities and treat the sexes as economic equals are vital, as are policies which recognise and reward the valuable but often non-monetary contributions of women. Gender-responsive coronavirus policies are not only smart economics, but provide opportunities to do the right thing – because how economies emerge from this crisis will be dependent on how inclusive their policy responses are.
In Yemen, a deadly concoction of arms sales, conflict and Covid-19
Philippines: Bangsamoro, between conflict and Covid-19
Discontinued: America’s Continuous Bomber Presence
Alvin Y.H. Cheung 17 Jun 2019 13:30
The deeper malaise in Hong Kong’s civil service
The political capture of once neutral institutions of government should be just as alarming.
Stephen Grenville 27 Jun 2017 17:54
What did we learn from the Asian crisis?
The common view was that the Asian countries, like Icarus, had flown too close to the sun in their hubris-fueled growth and had crashed back to earth.
Matthew Sussex 8 Jun 2018 06:00
Time for reason, not emotion, in the “China influence” debate
Australians have been passengers, if not active participants, in our own polarisation.
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CVS Caremark launches iPhone app
CVS Caremark, Woonsocket, R.I., has released the Caremark.com iPhone application. Available at no cost, the application provides all iPhone users with access to the Drug Information Database and allows CVS Caremark plan members to login and manage their prescriptions online.
“It is important to note that iPhone users that are not CVS Caremark PBM members only have access to the Drug Information Database through the application,” says Tim Kurth, vice president, eBusiness at CVS Caremark. “The Drug Information Database gives consumers the opportunity to research particular prescription medications, get information about how to take them, learn about available generic drug alternatives, see an image of the drug, learn about side effects and precautions, and much more.
“By making this function available to consumers who may not be current CVS Caremark PBM members, we are reinforcing our position as a convenient resource for consumers for information about their pharmacy care.”
CVS Caremark PBM members log in to refill prescriptions, check order status, view their prescription history and request a new prescription.
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Equitable Life update
Norton Rose Fulbright
United Kingdom August 18 2008
The Parliamentary Ombudsman’s report on alleged maladministration by the public bodies responsible for the regulation of the Equitable Life Assurance Society was published on 17 July 2008.
In the report, entitled “Equitable Life: A decade of regulatory failure”, the Parliamentary Ombudsman sets out ten findings of maladministration that occurred during the supervision of Equitable Life from 1991 to 2001, five against the Financial Services Authority, four against the Government Actuary’s Department and one against the Department of Trade and Industry.
The report recommends that the regulatory bodies apologise for their failures and that the Government should establish and fund a compensation scheme to provide compensation for any loss suffered by any person due to the maladministration.
Alistair Darling has instructed lawyers to review the report and is to wait until the House of Commons returns from its summer break before giving any views on compensation claims.
View the report.
Employee Benefits & Pensions
UK House of Commons
UK Department of Trade and Industry
Discharge of a guarantee *
Construction of contracts: priority of documents *
Orient-Express Hotels Ltd v Assicurazioni Generali SA *
Frustration, breach of contract and repudiation *
The role of the security trustee *
Related United Kingdom articles
Parliamentary Ombudsman calls on UK government to apologise to Equitable Life policyholders and to establish a compensation scheme *
Judicial Review granted as HM Treasury found to have acted with injustice and maladministration *
Equitable Life *
EC Ombudsman Issues Recommendation in Case Regarding Lack of Access to Catalog of Nanomaterials Used in Cosmetics * - European Union
The European Ombudsman: potential for a competition role * - European Union
European Ombudsman closes maladministration inquiry into public statements by former Competition Commissioner * - European Union
Barbara Clancy
International Rugby Board
"The newsfeeds deliver us the most recent legal analysis and practical information. There seems to be a broad analysis which is beneficial to us in analyzing various areas of law. It provides a snap shot update of various legal developments and assists us in staying current. The articles are well covered and include the right amount of detail. The size and depth of articles are good too, so we can get to the information one needs very quickly. The articles are typically of high calibre and from high-calibre authors who provide sufficiently succinct articles so that one can learn much about new developments in a short amount of time. I like the format because it is easy to scan for relevant articles. It's a great tool. I like the fact you can tailor the newsfeeds by jurisdiction and work area, and only receive information relevant to your practice."
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Positive Community Newspaper
about life
Realty Executives Milford Recognizes Realtors
MILFORD - Rebecca Repecki along with brothers John and Brian Sweeney are realtors from Realty Executives Milford who have been recognized for their outstanding accomplishments over the past several months.
Rebecca Repecki. Contributed.
Realty Executives Branch Office Manager Nicole Patrisso said, “It is an honor to recognize sales Associate Rebecca Repecki, who has had a fantastic year in real estate despite the enormous challenges brought on by Covid 19. Rebecca is extremely well respected by her clients and her peers for her professionalism, her wealth of knowledge and expertise as a local Realtor. A Milford resident for over 40 years, Rebecca has continued to be involved in the local community.”
Brian Sweeney. Contributed.
Patrisso added that “Brothers John and Brian Sweeney, two powerhouse Realtors, are recognized for their hard work and successes over this past year. They are both experienced, knowledgeable and professional Realtors who leave no stone unturned when representing their clients. Both brothers were born and raised in Matamoras and are well known in the community for all the volunteer work they have done over the years.”
John Sweeney. Contributed.
For more information or to reach any of these Realtors, please call the Realty Executives Milford Branch Office at 209 East Harford Street at 570-296-5800. Visit the company website:
www.RealtyExecutives.com , or go to https://www.facebook.com/realtyexecutivesmilford/.
Upper Delaware Council elects 2021 officers
Upper Delaware Council launches Project Review Video on Jan. 25
NARROWSBURG — The Upper Delaware Council (UDC) invites local municipal officials, community advocates, residents, and the general public to attend the virtual premiere of the Project Review Workbook 2
Brown begins sixth term as a PA State Representative
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Morocco / en
Continue to Morocco
ON THE ROAD WITH DREAM WIFE
EVER WONDERED WHAT LIFE IS LIKE TOURING THE WORLD AS AN UP-AND-COMING BAND? MARSHALL IS GIVING YOU AN EXCLUSIVE LOOK OF WHAT LIFE IS LIKE ON THE ROAD WITH SOME OF OUR FAVOURITE ARTISTS. SO LET US INTRODUCE YOU TO DREAM WIFE, THE LONDON-BASED POP PUNK TRIO THAT’S KNOWN FOR THEIR RAUCOUS, HIGH-ENERGY LIVE SHOWS, AS WELL AS THEIR BITING ANTHEMS OF FEMALE EMPOWERMENT.
Dream Wife reckon their best gig ever was when they turned the Moth Club into a graveyard for Halloween. Rakel Mjöll recalls how bassist Bella Podpadec spent weeks making fifty tombstones to scatter around the venue, while some of their fans brought their own to the show, their first big London headline slot. "It was great, and that whole night was so much fun, it was one of the best parties I’ve ever been to," she says. "The tombstones were everywhere, and because you got a goodie bag when you left, you got a tombstone as well - people were running out of Moth Club with them."
While the residents of Hackney might have been perturbed to see excited fans running past their front doors wielding graves, it says a lot about the creative energy and sense of fun that's shaped the rise of the now London-based trio, who channel Yeah Yeah Yeahs and the Ramones into effervescent songs about youth, love and empowerment.
They met at art college in Brighton, where their first gigs happened at house parties, galleries and benefits for a theatre, rather in than standard music venues. Since their self-titled debut album was released in January 2018, they've played over 100 gigs, travelling up and down the country in a tour van resounding to the likes of ABBA, Madonna, Prince and US punk rock troupe Sheer Mag. We catch up with Rakel Mjöll in the Dream Wife tour bus en-route to Paris from a show in Berlin supporting Garbage.
HOW IS IT PLAYING IN SUPPORT OF YOUR HEROES?
We did one with Sleigh Bells, who are one of our favourite bands ever, and The Kills who we absolutely loved as teenagers. We were joking that we were fulfilling our thirteen-year-old teenage fantasy - going on tour with the bands that we loved at the time when we discovered music and that whole world seemed so far away.
HOW HAS THE MONTHS OF TOURING THROUGH 2018 BEEN?
It’s become a really beautiful routine. They’ve all been great shows, we haven’t played one where we’ve felt like it didn’t work out how we wanted it to. It’s been really wonderful.
IT'S NOT OFTEN THAT BANDS DESCRIBE TOURING AS "A BEAUTIFUL ROUTINE"
Well it is a routine, but we’re grateful for things. For example, if there’s something interesting on the rider, like when Alice got a boiled egg the other day, and we were all like oh my god!
IN THE FILM YOU DID FOR I-D AND MARSHALL, YOU TALKED ABOUT WRITING SONGS ON THE ROAD, WERE YOU STILL ABLE TO DO THAT THIS TOUR OR HAS IT JUST BEEN TOO HECTIC?
The good thing is that you get ideas and since you’re always in transit, there’s a lot of opportunities to be inspired, especially with the conversations that you’re having with strangers, and you’re meeting old friends, new friends. Those conversations stay with you and that sometimes makes it into a song.
WHY IS IT IMPORTANT FOR YOU TO HAVE THE VISUAL SIDE, LIKE THE MOTH CLUB HALLOWEEN GIG WITH THE TOMBSTONES?
It just makes it more fun, for all of us. You should have many different outlooks that you’d like to explore creatively, anything from creating merch to videos. It’s just like why not? So, at one of our live shows we had a prom scene, it was so funny, everyone got involved, we got friends of ours on stage, who started making out, like high school dance making out, and that’s how we ended: a mixture of making out and mosh pits on stage. You’re here to be entertained, and adding a little bit of extra flair to it just makes it such a good party.
IN THE FILM YOU TALK ABOUT A FEELING OF SOLIDARITY AT GIGS. IS THAT AN IMPORTANT PART OF LIVE MUSIC FOR YOU?
Yeah massively! If you have a platform, use it to benefit others and we think that a lot of songs touch on breaking gender stereotypes and as well, we tackle different issues that we’ve experienced as women. We think it’s really important that we bring that to the show sometimes. We think we should be talking about things like “what is gender?” It’s a construct that we should dismantle.
AND IT’S ALWAYS INCLUSIVE?
Anyone could be at our show, a sixteen-year-old girl in the audience with an eighty-year-old punk rocker which is so cool. So, we kind of just want to acknowledge all the audience members, and we want them to respect each other and look out for each other.
WAS THE 'GIRLS TO THE FRONT' POLITICS OF RIOT GRRRL A BIG INFLUENCE ON YOU, AND HOW DO YOU BRING THAT INTO YOUR OWN?
We actually got into Bikini Kill and the Riot Grrrl movement after we formed this band, we respect it completely and it has really guided us in ways of understanding the heritage and place we come from as female musicians playing more ‘aggressive’ music. It's that thing of channelling negativity into positivity and finding a solidarity together at a gig, it's about everyone respecting everyone else in the room. We have a moment in our set where we call the ‘bad bitches’ to move towards the front, it still feels important to make that moment for women and female identifying people at a gig, even though Riot Grrrl was over twenty years ago, now.
HOW DO YOU STAY HEALTHY ON TOUR?
For us it's about looking after our bodies. When we are playing a sweaty and physically intense show every night you have to stretch off and be kind to your body, let yourself rest. Trying to eat healthy is also really important, when you are in transit a lot it's hard not to just buy bad food from gas stations, it's worth eating the right things to sustain your health when you wanna be able to bring it to the rock show night after night.
WHAT'S THE KINDEST THING ANYONE HAS SAID ABOUT ONE OF YOUR GIGS?
‘I wanna start a band now’
AUTHOR LUKE TURNER
PHOTOGRAPHER LIBBY BURKE WILDE
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You are browsing from: Finland. Change country & currency
Odette in a New Finish
Massproductions extends the Odette collection with a new, durable galvanized finish. The series is now available in six standard versions.
“The name Odette refers to the white swan in the ballet of Swan Lake. Like a series of ballerinas dancing across the stage, a series of Odette stools become a visual experience of dynamic movement in random directions”, says Chris Martin, Massproductions’ designer-in-chief and co-founder.
When Chris Martin designed the Odette stool in 2009, he wanted to make a strong impression with a small gesture. By adding a twist to the footrest of the bar stool, visual interest is added with a simple action. The gesture also gives the user a footrest where the feet can rest comfortably in different positions. Odette’s padded seat adds a softness and contrast to the chair’s otherwise strong and explicit shape.
Today the bar stool can be found at, amongst other locations, Stockholm’s Central Station and Arlanda Airport. In 2015, 700 bar stools were delivered to Arlanda, a place that is open 24/7 and is visited annually by 26 million travellers. Thanks to Odette’s durable construction, only two stools have needed repair since they were installed.
The products in the Odette series have a five-year guarantee and are certified with the Swedish sustainability and quality label “Möbelfakta”.
Odette Stool Hot Dip Galvanized
Odette Stool
Odette Coffee Table
Odette Dining Table
Country Finland
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Search MedicallyPrime.Com
MedicallyPrime.Com
News from the Medical World!
By Sheela
When the semester shifted online amid the COVID-19 pandemic last spring, Cornell University instructor Mark Sarvary, and his teaching staff decided to encourage -- but...
A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. In a...
New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the...
COVID-19 in the U.S., One Year Later
By Lizzy
It was one year ago -- Jan. 20, 2020 -- that the first case of SARS-CoV-2 infection was reported on U.S. soil. It was still...
Cash-Only Medical Practice?
I am an orthopedic surgeon, and I only take cash. When I tell people this, it usually conjures up images of some money-grubbing doctor eager...
Worth the sting: Cuba’s scorpion pain remedy
By Lizzy on December 15, 2018
HAVANA (Reuters) – Once a month for the last decade, Pepe Casanas, a 78-year-old Cuban farmer, has hunted down a scorpion to sting himself with, vowing that the venom wards off his rheumatism pains.
A worker extracts venom from a scorpion to produce homeopathic medicine Vidatox at LABIOFAM, the Cuban state manufacturer of medicinal and personal hygienic products, in Cienfuegos, Cuba, December 3, 2018. REUTERS/Stringer
His natural remedy is no longer seen as very unusual here.
Researchers in Cuba have found that the venom of the blue scorpion, whose scientific name is Rhopalurus junceus, endemic to the Caribbean island, appears to have anti-inflammatory and pain relief properties, and may be able to delay tumor growth in some cancer patients.
While some oncologists abroad say more research is needed to be able to properly back up such a claim, Cuban pharmaceutical firm Labiofam has been using scorpion venom since 2011 to manufacture the homeopathic medicine Vidatox.
The remedy has proven popular.
Labiofam Business Director Carlos Alberto Delgado told Reuters sales were climbing 10 percent annually. Vidatox already sells in around 15 countries worldwide and is currently in talks with China to sell the remedy there.
In Cuba, where tens of thousands of patients have been treated with Vidatox, each vial costs under a dollar. On the black market abroad it can cost hundred times that – retailers on Amazon.com are seen selling them for up to $140.
“I put the scorpion where I feel pain,” Casanas said while demonstrating his homemade pain relief with a scorpion that he found under a pile of debris on the patch of land he cultivates in Cuba’s western province of Pinar del Rio.
After squeezing it long enough, it stung him and he winced.
“It hurts for a while, but then it calms and goes and I don’t have any more pain,” he said.
Casanas, a leathery-skinned former tobacco farmer who now primarily grows beans for his own consumption, said he sometimes keeps a scorpion under his straw hat like a lucky charm.
It likes the shade and humidity, he says, so just curls up and sleeps.
FROM FARM TO LAB
In a Labiofam laboratory in the southern Cuban city of Cienfuegos, workers dressed in scrubs and hairnets tend to nearly 6,000 scorpions housed in plastic containers lined up on rows of metal racks.
Every few days they feed and water the arachnids that sit on a bed of small stones. Once a month, they apply an 18V electrical jolt to their tails using a handcrafted machine in order to trigger the release of a few drops of venom.
The venom is then diluted with distilled water and shaken vigorously, which homeopathic practitioners believe activates its “vital energy.”
The scorpions are caught in the wild as Labiofam workers believe their venom – which is not dangerous – is not as potent when raised in captivity.
After two years of exploitation in the “escorpionario,” they are released back into the wild.
Dr. Fabio Linares, the head of Labiofam’s homeopathic medicine laboratory who developed the medicine, said Vidatox stimulates the body’s natural defense mechanisms.
“After four to five years (of taking it), the doctor whose care I was in told me that my cancer hadn’t advanced,” said Cuban patient Jose Manuel Alvarez Acosta, who was diagnosed with prostate cancer in 2008.
Still, Labiofam recommends Vidatox as a supplemental treatment and says it should not replace conventional ones.
Reporting by Sarah Marsh, editing by G Crosse
Published in Health News
More from Health NewsMore posts in Health News »
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Western investors buy into Islamic leasing fund
06 January 1995 By MEED Editorial
Non-Islamic investors are channelling money into an Islamic leasing fund promoted by The United Bank of Kuwait (UBK). The flow of funds reflects a growing appetite for Islamic instruments from conventional Western institutions, who are looking to diversify their investment portfolios after a volatile year for the international bond and equity markets.
The London-based UBK has underwritten The Leasing Fund for up to $100 million - the bank's target for investment by end-1995. It had made investments of about $21 million by mid-December and expects this to rise to $35 million by mid-January, says Duncan Smith, head of UBK's Islamic investment banking unit.
'We are getting approaches from outside our usual Islamic banking constituency because this is a good deal,' Smith says. 'The Leasing Fund is a real asset thing, not a financial asset, providing capital which can rise if interest rates or inflation go up.'
The fund invests mainly in low-tech equipment for lease to US Fortune 500 companies. Cash funds have proved increasingly attractive given the disappointing performance of the bond and equity markets in 1994, leading investors to look for other instruments.
The Leasing Fund is an open-ended fund, authorised and regulated by the Central Bank of Ireland. Minimum subscription is $500,000.
Genel Energy plans new wells in Iraqi Kurdistan
RAK airport signs agreement with Gulf Air
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You are here: Home1 / News2 / Articles3 / CONNECTING THE SHOP FLOOR
CONNECTING THE SHOP FLOOR
December 18, 2015 /in Articles /by Memex
From FABSHOP Magazine Direct
Interconnectivity was a dominating theme at Fabtech, and it is evolving into a new concept with a new buzzword, ‘Industry 4.0.’ Its meaning is broad and it will take some time to tame it into something useful, but it’s coming fast and it will affect us all.
By Larry Adams, Senior Editor
The Internet of Things (IOT). The Industrial Internet of Things (IIOT). Big data, the Cloud, Industry 4.0. These and other buzzwords have been flying around the last few years, but the buzz for the most part seemed to only briefly and intermittently touch the fabricating industry. You likely know that if you’ve been reading the pages of Fab Shop this year.
That flight plan altered perceptively as this interconnectivity concept landed at Fabtech; not with a thud or with a tentative toe, but with a resounding splash as equipment manufacturers of all sorts, from welding companies to waterjet manufacturers, laser suppliers to robotics developers, all made it clear that their machines could communicate with each other—as well as upstream and downstream vendors and end users—and that a shop floor could now be connected in this way whether via Industry 4.0, IIOT or some other nomenclature.
Just what is Industry 4.0, or its other related names, mean? That is the question that Editor Ed Huntress posed in his Editor’s Letter (see page xx), and while individual distinctions could probably be seen, the concept involves smart machines utilizing dedicated sensors and other information gathering devices, with some networking functionality that allows machines and planning systems within and outside of the workplace to better coordinate and optimize productivity.
According to Tobias Reuther, automation manager at Trumpf Inc., today’s interconnectivity technology allows manufacturers to “look at more than just a single machine, and look to the entire shop and the entire network of manufacturing.” One important goal, he added, is to use this data to add value to a job and remove as much of the non-value added activities as possible.
(These systems are also, in a sense, an homage to tomorrow’s workforce, that Matthew Fowles, global marketing manager for LVD Strippit, said is “far more IT knowledgeable than they are about cutting and welding. So, we are building that intelligence into the software.”)
ESAB WeldCloud
LVD Strippit showcased its interconnective capabilities both in the real world with a laser system and a panel bender operating using in situ data to create parts, and a virtual factory that they used for showing interested attendees how this concept can work in a fast paced, oft-changing factory floor in which customers are ordering smaller batches of parts that are often more complex than ever before.
“The company’s (LVD) philosophy over the years has always been what we call ‘integrated sheet metalworking’,” said Fowles. “Fifteen years ago, what that meant was being able to take an electronic part, take it through the CAM process and be able to make an accurate part, the first time. Now it is a lot more.”
But, LVD’s concept is a lot more than just 4.0, Fowles said showing a process map drawn on a wall of the booth depicting how a typical fab shop layout works.
At the show, they ran a live network of machines working with LVD’s centralized CADMAN database, said Fowles. “All of our machines are now social machines. All of our controllers are telling the central databases what they are doing at any given time.”
LVD CADMAN Job Part Manufacturing
The company’s CADMAN suite is LVD’s answer to full process integration between software and bending, laser cutting, and punching machines. It comprises a core database and works on different levels: interacting with ERP, efficiently classifying jobs with its CADMAN-JOB module and performs offline work preparation with its touch controls for bending and laser cutting, and interacts with the machines and the company’s Touch-i4 tablet to quickly view and analyze data.
Jamie Forsyth, LVD’s product specialist for offline software, said that CADMAN job can be set up on any PC for any user and gives an overview of what is going on in the entire workplace. In terms of a company ERP system, she said that orders that are sent into ERP are automatically flowed into the CADMAN software and everything that goes into that job is known. The system automatically determines such necessities as the required tooling and finds programming solutions to machining that part.
This could mean taking orders from multiple customers and nesting the parts to better optimize production or getting a rush job to replace bad parts.
LVD Cadman-L Machining
While terminology is different, Trumpf also showcased multiple ways to better optimize production. Its TruTops Boost software integrates all design and programming capabilities, and eliminates the need to have different programs for different technologies.
In addition, Trumpf announced it had created a spin-off company calledAXOOM that Reuther says supports the entire production value chain using Industry 4.0. Like LVD, the goal is to capture data—“anything, anywhere at anytime in real time,” Reuther said. This is true for better organizing jobs and how to run them, but it is also true for predictive maintenance and other quality related requirements.
“It used to be the industry would run a machine for a week and then we would go back and see how it went and then try to optimize the process. Now, with this method, it can tell you where to improve the process in real-time.”
LVD Strippit Cadman Chart
For instance, Reuther, pointing at a laser system, said that if that nozzle were starting to go bad, sensors on the machine would alert the operator, and perhaps even automatically order the required part. In all, he said that approximately 20 parameters on a laser cutter can be tracked and information on the machine or machine activity can be tracked.
The AXOOM system features an order management module, resource management module, and a logistics module. The foundation for the production planning module and the shop floor is a dynamic planning algorithm that responds instantly to rush orders or malfunctions and recommends solutions. After the production manager has signed off on the incoming order, suggestions for optimal production scheduling are automatically generated. The complex tasks of material provisioning and scheduling of machines and personnel – along with determining the sequence of processing steps – are optimized independently by the AXOOM platform, acting as a manufacturing advisor. On the shop floor, the operator can decline the advice.
LVD’s Jamie Forsyth operates tablet
Another company promoting its interconnectivity capabilities was Mazak Optronics, but in a slightly different way. In addition to its fabricating machines, Mazak has a substantial presence in the traditional chip making side of the metal working industry and as such has a lot of experience using MTConnect, an open protocol developed the AMT- The Association For Manufacturing Technology, that has been successfully tested by NIST and other groups to show how even very dissimilar machines and machine types can communicate with each other, said Dave Edstrom, chief technology officer for MEMEX Inc., the company that has partnered with Mazak to help analyze data collected by Mazak machines.
MEMEX’s “shop-floor-to-top-floor communications platform” is called Merlin and will work with Mazak’s new iSMART Factory concept that it says will harnesses the power of connectivity to optimize manufacturing operations at every level.
According to David Widlund, regional sales manager for Mazak, all the Mazak fabricating and metalworking machines come standard with MTConnect. “Now, we can take all the data out of the machine and go to the company that we have partnered with, Memex, and get a full dashboard on each machine, just like you would on the chip side.”
Another company utilizing Industry 4.0 is ESAB Welding & Cutting Products.In its huge, compound of a “booth” ESAB showcased a variety of welding technologies, and set among the mammoth space was an area dedicated to its new WeldCloud online data management platform. Weld Cloud integrates with other customer systems such as ERP, MRP, and QA to generate and analyze data.
Using any device with a web browser, users access applications and dashboards with functionality tailored for the job needs of different personnel: operations managers, quality managers, engineers, welders, maintenance staff, training supervisors, and others.
With WeldCloud, customers can facilitate traceability from single welds to the complete product utilizing a database that contains key information of every weld seam. It can develop weld schedules on a single machine, move them into the Cloud, and then push them out to other welding systems and remotely manage welding parameters, set limits, and set alarms for deviations.
It can also ensure complete documentation of filler metals, consumables, operator qualifications, and parameters, which is critical for companies that are required to keep this information for their customers or for standards certification agencies.
“While faster welding speeds and increased deposition rates reduce cycle time, automating activities that surround the welding processes enables users to make quantum leaps in productivity, quality and machine efficiency possible,” says Roul Kierkels, acting product manager for WeldCloud.
To see the full article please click here
0 0 Memex /wp-content/uploads/logo.png Memex2015-12-18 13:34:512015-12-18 13:34:51CONNECTING THE SHOP FLOOR
The future of optimization and automation in sawmilling Aero Pacific Initiates Plant-Wide Purchase of MERLIN Enterprise Edition Software...
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Ministry of Foreign Affairs of Turkmenistan
Articles & Statements
RECCA
Briefing on RECCA VII preparations was convened in New York
New York. A briefing on RECCA VII preparations was made on September 21, during the Second Senior Officials Meeting of the Heart of Asia-Istanbul Process (HoA-IP) in 2017 chaired by H.E. Adela Raz, Deputy Foreign Minister for Economic Cooperation of Afghanistan and H.E. Mr. Araz Azimov, Deputy Foreign Minister of Azerbaijan in New York. The meeting included a keynote address by H.E. Salahuddin Rabbani, Minister of Foreign Affairs of Afghanistan.
The briefing on RECCA VII was made by Mr. Hassan Soroosh, Acting Director General of Economic Cooperation and included an overview of the preparations for RECCA VII including the ongoing preparation of the Annual Review 2017, the outcomes of the First RECCA National Focal Points Meeting as well as the outline of RECCA VII program.
Referring to the increasing number of participating countries and organizations which reached a record of 40 countries and 30 regional and international organizations in the RECCA VI (Kabul, September 3-4, 2015), the RECCA regional and partner countries and organizations were encouraged to participate in the RECCA VII at the highest level.
The participants welcomed the ongoing efforts to bring greater synergy and complementarities between RECCA and HoA-IP.
Türkmenistanyň Daşary işler ministrliginiň Bildirişi
Events on the occasion of World Cycle Day have been held with the participation of the President of Turkmenistan
The meeting of the Ministers of Foreign Affairs of Turkmenistan and Turkey was held
Working meeting on the international transit-transport route “Caspian Sea-Black Sea”
Meeting through videoconferencing held in the MFA of Turkmenistan
Social sphere
Avaza National Tourist Zone
MINISTRY OF FOREIGN
AFFAIRS OF TURKMENISTAN
Turkmenistan abroad
Representations in Turkmenistan
Consular service
Phone: +993 (12) 44-56-92
Fax: +993 (12) 44-58-12
Reception: +993 (12) 44-56-87
Press service: +993 (12) 44-56-04
744000, Ashgabat, Archabil av., 108
Ashgabat, Turkmenistan
© 2021 Ministry of Foreign Affairs of Turkmenistan
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The WTI crude price stood at $40.43 in early trading today, while Brent was at $42.01/bbl.
China is on pace to purchase less than 20% of the energy products it agreed to buy under this year’s Phase 1 trade agreement with the U.S.
Dominion Energy and Duke Energy are abandoning their planned $8 billion Atlantic Coast Pipeline due to regulatory obstacles, sowing doubts about large-scale energy projects in the future. Dominion also is selling its gas transmission business. Duke Energy reaffirmed its commitment to invest in renewable energy.
Germany passed legislation to phase out the use of coal as an energy source by 2038, the first major country to do so.
Gasoline retailers are enjoying record margins with high July Fourth holiday demand coupled with low wholesale prices.
Dow has agreed to sell its rail logistics assets as part of a plan to focus on its product-producing assets.
The transportation and warehousing sector saw nearly 100,000 job gains in June:
Amazon is delaying its Prime Day for a second time, from September to October, out of concerns about supply chain disruptions due to rising COVID-19 infection rates.
The rolling seven-day average of new COVID-19 cases exceeded 48,000 on Sunday, a record for the 27th consecutive day:
Former epicenter New York, which has largely tamed the virus, has been replaced by four concerning hot spots: Arizona, California, Florida and Texas, all of which reported daily record infections over the holiday weekend.
Florida, with more than 11,000 new COVID-19 cases reported on Saturday, and Texas, with more than 8,000, accounted for 40% of national infections over the holiday weekend.
Arizona’s case count has risen at a 4.1% rate for the past seven days.
U.S. manufacturing activity is rebounding but remains well below 2019 levels:
Goldman Sachs lowered its outlook for the U.S. economy in 2020 from a 4.2% contraction to a 4.6% contraction in expectation of a smaller rebound in the third quarter as more states retrench in the face of accelerating COVID-19 spread.
As the second-quarter reporting season for public companies begins, average revenues are expected to be down 11.1% and earnings down 43.8%.
Used car sales and prices have rebounded strongly in June due to stimulus spending, low interest rates and shortages of new cars as automakers ramp up production.
With consumers looking for off-road adventures during the pandemic, Ford is reviving its Bronco brand after 25 years in retirement.
Testing is proving to be a difficult and expensive protocol to implement for companies reopening facilities and offices.
Kroger has received FDA approval to provide at-home COVID-19 testing kits to all its frontline workers through an affiliation with a laboratory partner.
The pandemic is accelerating a shift toward a cashless economy as consumers shop more online and turn to cards and cashless payments out of safety concerns.
More than 200 medical experts from 32 countries are pressing the World Health Organization to definitively acknowledge the airborne transmission risk of COVID-19.
U.S. COVID-19 infections are approaching 3 million today.
India surpassed Russia with the third-highest COVID-19 infections in the world behind Brazil and the U.S.
Tokyo, which has experienced triple digit new COVID-19 infections for five straight days, is preparing for a possible second wave.
Israel’s cabinet will meet today to consider new restrictions and economic measures to address a renewed surge in infections.
Unlike past recessions, the COVID-19 recession has impacted service sectors first and foremost, hitting Latino and Hispanic workers particularly hard since they constitute about half of service workers.
Job losses among migrant workers around the world could reduce remittances by up to 20% this year, dealing a further economic blow to many developing countries.
Plastimagen, Mexico’s largest plastics trade show, has been postponed from November to January 2021.
Berlin’s public transportation company initiated an ad campaign urging riders to forego deodorant as a means of forcing others to properly wear face masks to cover their noses.
Today we welcome Lindy Holland, Market Manager, Sustainability, back to work after a challenging bout with COVID-19.
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Philadelphia Union sign Cameroonian international Olivier Mbaizo
April 17, 201810:50AM EDT
Dave ZeitlinContributor
Follow@ DaveZeitlin
TRANSFER TRACKER STATUS: Signing
The Philadelphia Union on Tuesday added an intriguing prospect to an already-young backline, signing Olivier Mbaizo, who will occupy an international roster spot.
Mbaizo, a 20-year-old native of Cameroon, signed with the club’s USL affiliate, Bethlehem Steel FC, ahead of the 2018 season. He’ll likely continue to see most of his minutes this season with the Steel, along with fellow Cameroonian Eric Ayuk.
“Olivier trained with the Union first team throughout our preseason, and it became clear that he has the potential to immediately contribute at the MLS level,” Union sporting director Earnie Stewart said in a statement. “He has earned this quick ascension to our first team through his play in preseason, and we look forward to further integrating him and assisting with his development.”
Before coming to the Steel in January, Mbaizo played in Cameroon for Union Douala and Rainbow FC, where he had four assists in 10 appearances last season. With Douala, he helped the club earn 12 shutouts in 34 games and also started two matches in the 2016 Confederations of African Football Champions League.
Internationally, Mbaizo recently earned a call-up to train with the Cameroonian senior national team after stints with their U-17 and U-20 squads. He started three matches and scored a goal in the 2017 Africa U-20 Cup of Nations.
The Union have focused a lot on defensive youth this season. In last Friday's 2-0 loss to Orlando City SC, due to a couple of injuries, teenagers Auston Trusty, Matthew Real and Mark McKenzie all played together, along with 24-year-old Keegan Rosenberry.
The Union are back in action Saturday at FC Dallas (8 pm ET; TV & streaming info).
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Welcome to MovieArt Original Film Posters!
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ROCKET TO THE MOON (1967) 18562
Warner Pathe Original U.S. One-Sheet Poster (27x41) Folded Very Fine Plus Condition
Warner-Pathe Original U.S. One Sheet for the film THOSE FANTASTIC FLYING FOOLS (1967). The original title for this British film is JULES VERNE'S ROCKET TO THE MOON. The story is based loosely on Verne's novel FROM THE EARTH TO THE MOON. Of course this story had been made previoiusly in 1958, but in a straighter way. This movie was kind of a send-up in that wacky way of sixties comedies. The film stars Burl Ives, Troy Donahue, Gert Frobe, Terry Thomas, Hermione Gingold, Daliah Lave, Lionel Jeffries and Dennis Price. This was one of those films like THOSE MAGNIFICENT MEN IN THEIR FLYING MACHINES or THOSE DARING YOUNG MEN IN THEIR JAUNTY JALOPIES - big international casts carry the movie with hijinks of all kinds. The movie was directed by DON SHARP The poster is in very fine condition. MovieArt Austin guarantees that this poster is the authentic U.S. one-sheet for this film. MovieArt Austin will sell NO reproductions.
Burl Ives - Actor
Troy Donahue - Actor
Gert Frobe - Actor
TERRY-THOMAS - Actor
Hermione Gingold - Actor
Daliah Lavi - Actor
Lionel Jeffries - Actor
Dennis Price - Actor
Sinead Cusack - Actor
Edward de Souza - Actor
DON SHARP - Director
TIME FOR KILLING, A (1967) 18563
Columbia Pictures Original One-Sheet Poster (27x41) Folded Very Fine Plus Condition Columbia Pictures Original U.S. One-Sheet Poster for the movie A TIME FOR KILLING (1967) starring Glenn Ford,...
BEACH RED (1967) 4225
United Artists Original U.S. One-Sheet Poster (27x41) Folded Very Fine Condition Original U.S. one-sheet poster for the Cornel Wilde directed film BEACH RED (1967). The movie stars Wilde, Rip...
TRIP, THE (1967) 26687
American International Original Italian 79x55 Poster Folded Very Fine Condition Original American International Italian 79x55 poster for the movie THE TRIP (1967) starring Peter Fonda, Jack...
CASINO ROYALE (1967) 28629
Columbia Pictures Original U.S. 30x40 Poster Rolled Very Good Condition Columbia PIctures Original U.S. 30x40 Poster for the James Bond spoof CASINO ROYALE (1967). This hot mess of a James Bond...
HOTEL (1967) 18532
Original Warner Brothers One Sheet Poster (27x41). Folded. Very Fine Condition. Original Warner Brothers One Sheet Poster (27x41) for the Richard Quine drama, HOTEL (1967) starring Rod Taylor,...
ROCK, ROCK, ROCK! (1956) 11099
DCA Original One-Sheet Poster (27x41) Folded Fair Condition Original DCA One-Sheet Poster for the film ROCK, ROCK, ROCK (1956) starring Tuesday Weld, Chuck Berry, Connie Francis, Valerie Harper,...
Original Italian 2 Fogli Poster (39x55). Luigi Martinati Artwork. Folded. Fine Condition. Original Italian 2 Fogli Poster (39x55) for the Will Price music drama, ROCK, ROCK, ROCK! (1956)...
ROLLERBALL (1975) 3150
United Artists Original One-Sheet Poster (27x41) Folded. Very Fine Condition United Artists Original One Sheet Poster (27x41) for the Norman Jewison dystopian science fiction sports film ROLLERBALL...
ROSEMARY'S BABY (1968) 17705
Original Paramount Pictures Three Sheet Poster (41x81). Folded. Fine Plus Condition. Original Paramount Pictures Three Sheet Poster (41x81) for the Roman Polanski horror classic, ROSEMARYÕS BABY...
ROAD TO HONG KONG, THE (1962) 20392
Original United Artists 24 Sheet Poster (9 ft x 20 ft). Unassembled. Very Fine. Original United Artists 24 Sheet Poster (9 ft x 20 ft) for the Norman Panama spy comedy, THE ROAD TO HONG KONG (1962)...
ROCK 'N ROLL REVUE (1955) 7529
Original Studio Films One Sheet Poster (27x41). Linen-Backed. Near Mint. Original Studio Films One Sheet Poster (27x41) for the Joseph Kohn African-American musical extravaganza, ROCK 'N' ROLL...
CASABLANCA (1942) 7266
Original Warner Brothers 1992 Re-Release One Sheet Poster (27x41). Unfolded. Very Fine Plus Original Warner Brothers 1992 Re-Release One Sheet Poster (27x41) for Michael Curtiz romantic...
RING-A-DING RHYTHM (1962) 11118
Columbia Pictures Original One-Sheet Poster (27x41) Folded Fine Plus Condition Original Columbia Pictures One-Sheet poster for the Richard Lester musical comedy, RING-A-DING RHYTHM! (1962)...
ROMA (1972) 25769
Original United Artists Italian 2-sheet poster. (39x55) Folded. Fine Plus Condition Original United Artists Italian 2-sheet (39x55) for the Federico Fellini docu-drama fantasy, FELLINI'S ROMA...
Columbia Pictures Original One-Sheet Poster (27x41) Folded Fine Plus Condition. Original Columbia Pictures One-Sheet poster for the Richard Lester musical comedy, RING-A-DING RHYTHM! (1962)...
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Home > List of families > Orchidaceae > Corymborkis > corymbis
Corymborkis corymbis Thouars
Selected images: Click on each image to see a larger version and details of the record View all images (3)
Photo: Bart Wursten
By path from carpark to Big Tree, Chirinda Forest
Detailed records: Display species records QDS maps by: Google Maps Point records by Google Maps
Synonyms: Corymborkis corymbosa (Ridl.) Kuntze
Frequency: Occasional
Terrestrial orchid growing from a rhizomatous rootstock. Stem thin, somewhat straggling and bamboo-like, up to 1.5 m tall. leaves spirally arranged along the stem, dark green, plicate, lanceolate or elliptic, up to 24 cm long, narrowing at the base into a sheathing petiole; margin somewhat wavy. Inflorescences axillary and terminal, 4-12-flowered. Floral bracts lanceolate to ovate, 7-15 mm long. Flowers non-resupinate, 'spidery'. Sepals, petals and lip similar, more or less narrowly linear-spathulate, 6-8.5 cm long, green, petals and lip turning white when mature.
Derivation of specific name: corymbis: in a corymb or cluster, referring to the inflorescences.
Habitat: in deep shade in understorey of evergreen forest.
Altitude range: 100 - 1120 m
Flowering time: Jan - Feb
Worldwide distribution: Widespread in tropical Africa, South Africa , Madagascar and Mascarene Islands.
Mozambique distribution: MS,GI
Growth form(s): Terrestrial.
Content last updated: Wednesday 1 February 2012
Chapano, C. & Mamuto, M. (2003). Plants of the Chimanimani District National Herbarium and Botanic Garden, Zimbabwe Page 16.
Cribb, P.J. (1984). Orchidaceae (Part 2) Flora of Tropical East Africa Pages 243 - 245. (Includes a picture).
Fibeck, W. & Dare, M. (1993). Terrestrial Orchids in Zimbabwe. Excelsa 16 Page 55.
Golding, J.S. (ed.) (2002). Zimbabwe Plant Red Data List. Southern African Plant Red Data Lists. SABONET 14 Page 175.
Grosvenor, R.K. (1976). A list of orchids indigenous in Rhodesia. Excelsa 6 Page 79. As Corymborkis corymbosa
La Croix, I. & Cribb, P.J. (1995). Orchidaceae (Part 1) Flora Zambesiaca 11(1) Pages 6 - 7. (Includes a picture).
La Croix, I. et al. (1991). Orchids of Malawi A.A. Balkema, Rotterdam Pages 24 - 25. (Includes a picture).
Linder, H.P. & Kurzweil, H. (1999). Orchids of Southern Africa A.A. Balkema, Rotterdam, the Netherlands ISBN 90-5410-445-7 Pages 73 - 74. (Includes a picture).
McMurtry, D., Grobler, L., Grobler, J. & Burns, S. (2008). Field Guide to the ORCHIDS of Northern South Africa and Swaziland Umdaus Press, PO Box 11059 Hatfield 0028 South Africa Pages 38 - 39. (Includes a picture).
Pooley, E. (1998). A Field Guide to the Wild Flowers of KwaZulu-Natal and the Eastern Region. Natal Flora Publications Trust. Durban. Pages 124 - 125. (Includes a picture).
Strugnell, A.M. (2006). A Checklist of the Spermatophytes of Mount Mulanje, Malawi Scripta Botanica Belgica 34 National Botanic Garden of Belgium Page 133.
Summerhayes, V.S. (1956). African orchids XXIII Kew Bulletin 11(2) Page 224. As Corymborkis corymbosa
Other sources of information about Corymborkis corymbis:
Flora of Malawi: Corymborkis corymbis
Flora of Zimbabwe: Corymborkis corymbis
African Plants: A Photo Guide (Senckenberg): Corymborkis corymbis
African Plant Database: Corymborkis corymbis
BHL (Biodiversity Heritage Library): Corymborkis corymbis
EOL (Encyclopedia of Life): Corymborkis corymbis
ePIC (electronic Plant Information Center): Corymborkis corymbis
Flora Zambesiaca web site: Corymborkis corymbis
GBIF (Global Biodiversity Information Facility): Corymborkis corymbis
GRIN (Germplasm Resources Information Network): Corymborkis corymbis
iNaturalist: Corymborkis corymbis
IPNI (International Plant Names Index): Corymborkis corymbis
JSTOR Plant Science: Corymborkis corymbis
Kew Herbarium catalogue: Corymborkis corymbis
Kew Monocotyledon checklist: Corymborkis corymbis
Mansfeld World Database of Agricultural and Horticultural Crops: Corymborkis corymbis
Plants of the World Online: Corymborkis corymbis
Tropicos: Corymborkis corymbis
Wikipedia: Corymborkis corymbis
Hyde, M.A., Wursten, B.T., Ballings, P. & Coates Palgrave, M. (2021). Flora of Mozambique: Species information: Corymborkis corymbis.
https://www.mozambiqueflora.com/speciesdata/species.php?species_id=116240, retrieved 20 January 2021
Site software last modified: 24 September 2019 10:58am
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thecourier1 May 1, 2020
You know when you sit and think about who you were in high school or middle school, and all the changes and growth you’ve seen since that time in your life? That’s how I feel now, only my “middle school” is just August of 2019.
August feels like it was five years ago. Within eight months, all of our lives have changed so significantly. We have all been pushed into a period of growth, whether we wanted it or not. Crucial changes in our lives have sent us hurtling into the chaotic unknown without a chance to look back or say goodbye to what we knew. It has been unnerving, stressful, and truly heartbreaking.
When I took the position of Editor in Chief of The Courier, I knew that our biggest hurdle would be to spark interest with the student body. We wanted the newspaper to be something that students looked forward to on Fridays. We wanted it to reflect the student morale and the overall zeitgeist of campus. The student-run newspaper is not in place to serve faculty, staff, alumni, trustees, prospective students, or Monmouth fans. The paper is for the students of Monmouth College. There is a great responsibility that lies with the press, and even as a small campus newspaper, we take that duty to students seriously. Everything we publish is with the student body in mind, whether it is to entertain, to recognize, to encourage, to inspire, or to inform.
Missing campus as much as the next Fighting Scot, our staff members decided in March that it was the job of The Courier to continue publishing online, even if we weren’t physically in Monmouth, Illinois. Though the circumstances of our work were drastically changed, our mission remained the same: to be there for the student body. Throughout these last few weeks, we sought to be an escape back to Wallace Hall for Monmouth students world-wide – something to look forward to in the monotony of social distancing.
As we eventually transition out of this unprecedented period, our mission will remain the same. No matter the time, obstacle, or circumstance, The Courier will serve the student body of Monmouth College.
Next year, Shyanne Sheehan will take over as Editor in Chief, and I have no doubt that under her leadership the paper will continue to expand in its capacity and service to every student at Monmouth College. Within this academic year, we’ve seen more students than ever picking up Friday issues and perusing each section with their friends. We’ve seen so many individuals interested in writing and being a part of our staff and we welcome every single one. In my eyes, that is a mission accomplished.
Thank you for your loyalty, Monmouth.
Signing off,
Emma Hildebrand
Editor in Chief, The Courier 2019-20
thecourier1
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搜索结果为 Manuel Rafael Hernández C.
精确搜索
每页结果 15 25 50 75 100
结果43682
Rafael Hernández Colón 政治科学
Betascript Publishing (2010-08-21) - ISBN-13: 978-613-1-40484-9
Rafael Hernández Marín 音乐
Rafael Cedeño Hernández 历史
Rafael Hernández National College 教育学
Rafael Hernández Airport 建筑
José Manuel González Hernández
Association football, Goalkeeper (association football), C.D. Dragon, C.D. Vista Hermosa, C.D. FAS
Dict (2011-06-08) - ISBN-13: 978-613-6-65238-2
Rafael C. Castillo 新闻学
Association football, Defender (association football), Sporting de Gijón, CD Colonia Moscardó, Atlético Madrid C
Eddie Hernández
Association football, Forward (association football), C.D. Motagua, Platense F.C., BK Häcken
Dicho (2012-08-17) - ISBN-13: 978-620-1-47287-7
Manuel Lujan, Jr.
Manuel Lujan, Jr., Republican Party (United States), United States Secretary of the Interior
政治科学
Fernando Hernández (Footballer)
Association football, C.D. Saprissa, Costa Rica national football team, Francisco Hernández (footballer born 1949)
Crypt Publishing (2011-08-14) - ISBN-13: 978-613-6-62662-8
Juan Manuel Abal Medina, jr.
Cristina Fernández de Kirchner, Juan Manuel Abal Medina, Peronism
Manuel Zeitz
Association football, Midfielder, 1. FC Nuremberg, 1. FC Saarbrücken, Germany national youth football team
Mike Manuel
Christian country music, Wynonna Judd, Josh Turner, Diamond Rio, Ponzi scheme
Richmond – San Rafael Bridge
John F. McCarthy, San Francisco Bay, San Rafael, California, Richmond-San Rafael Ferry Company
SaluPress (2013-08-13) - ISBN-13: 978-620-1-57572-1
EASY C/C++
An Easy Approach to C/C++
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Is the Circular Economy the Next Disruptor?
Refurbishing, Reusing and Recycling are helping to squeeze more life out of all the ‘stuff’ being consumed. Could this be the next big disruptive trend in global markets?
For decades, households and companies have been recycling trash for the good of the environment. Now there’s an added incentive: it’s also good for the bottom line.
A new report by Morgan Stanley’s Sustainability Equity Research team argues that new technology and increasing climate-based legislation around the world is creating new business opportunities based on the circular economy.
A circular economy uses products, materials and resources for as long as possible, by refurbishing, sharing, leasing or recycling. The goal is to extend the life of all of the ‘stuff’ people accumulate, generating environmental and economic benefits along the way.
Institute for Sustainable Investing
EduIndia Fund Wins 2017 Sustainable Challenge
A Disruptive Trend
Pioneering companies in a number of sectors are already shifting in that direction. “The advantages for companies are numerous and center on increasing the amount of value they create and retain,” according to Jessica Alsford, lead author of the report “The Shift to a Circular Economy.”
“The circular economy is unlikely to be a key fundamental value driver for many stocks at this stage,” she adds, “but we do think that the move to a more circular economy will be a disruptive trend in the next few years. Those companies that move first to innovate and adapt should be well placed.”
Environmental concerns helped spark this shift. The global economy, driven by the consumer frenzy to have the latest, fastest, best new model, now must contend with climate change, water scarcity and damage to the physical environment. A ‘sharing economy’ mentality has flourished, with people sharing car rides and renting out space in homes rather than paying for hotels. Legislation, particularly in Europe, but also in parts of Asia and certain states in the U.S., has also increased requirements to waste not, want not.
Companies that embrace these trends can find new revenue streams and cut costs. “Minimizing waste reduces cost and changes in product design can make refurbishment and remanufacturing more viable,” says Alsford in the report.
Some are adopting entirely new business models which profit from extending the use of new products and then recycling the materials. This could give them a first-mover advantage over their competitors, especially if a more economizing consumer base continues to grow.
Expanding the Customer Base
Extending the life of existing products seems counterintuitive for businesses, but it does make sense, according to Alsford.
Remanufacturing and re-selling products can save on the cost of raw materials, and can expand market reach to include consumers unable to afford the latest new models of electronics like cell phones or high-end products like LED lighting.
The potential revenue benefit of selling refurbished goods is prompting some companies to redesign new products, to make them easier to break down and remanufacture.
Expensive health-care machinery like MRIs are targets for remanufacturing, to cut both production costs and to expand revenues through resales of refurbished units. “Remanufacturing retains much of the material and value included in the original product,” Alsford says. “This saves costs for the manufacturer with the potential for higher profit margins and returns on capital. It also potentially creates new customer opportunities by making expensive products more affordable.”
New innovations and technologies support the move toward a circular economy. In textiles, chemical processes are being developed to separate blended fibers and recycle the raw materials into new clothes. In the batteries market, economical recycling of lithium batteries is key as demand for hybrid and electric vehicles accelerates.
The rise in a circular economy has macro implications because it boils down to using less finite resources. Having access to refurbished products means more spending power for the individual, which could boost gross domestic product, according to a McKinsey study cited in the Morgan Stanley report. Importers of finite resources would also benefit.
The potential losers are the exporters of primary metals and other finite resources, says the report, and they tend to be developing, rather than developed countries. “The net effect would largely depend on a country’s ability to embrace new business models to offset any decline from primary raw materials,” says Alsford.
Morgan Stanley Research is writing a series of reports on the impact of the circular economy on market sectors. Contact your Morgan Stanley representative or Financial Advisor for the report “The Shift to a Circular Economy” March 15, 2017. Plus, more Ideas.
Fighting Forest Fires With Finance
Former Sustainable Investing Challenge winner, Blue Forest Conservation, is preparing to pilot a financing vehicle to fund forest restoration in California.
Renewable Energy Storage: The Next Play
Learn how renewable energy storage tech has the power to turn solar and wind energy into a reliable source of electricity generation for U.S. utilities.
Starbucks Adds to Sustainable Investing Menu
The coffee company adds to the growing menu of bonds tied to social and environmental projects with the first Yen sustainability bond by a non-Japanese corporate.
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Home » International Speaker » Noreena Hertz
Noreena Hertz
Decision-Making Guru & Renowned Economist
Noreena Hertz is a renowned thought leader and economist with an impressive track record in predicting global trends. In 2017 Noreena launched her own show MegaHertz:London Calling on Sirius XM in the US, providing insights and analysis on what is happening in Europe and also a European take on what is happening in the US.
Previously she was ITV News’ Economics Editor where she led ITV’s economics coverage. She has given Keynote speeches at TED, The World Economic Forum and Google Zeitgeist sharing platforms with President Bill Clinton, James Wolfensohn and David Beckham amongst others. Noreena’s thinking was the inspiration for Product (RED), which has raised hundreds of millions of dollars for the fight against HIV/AIDS in Africa. Most recently she has been exploring the world of today’s teenagers, who she has coined “Generation K”, with articles published in the UK, US, Europe and China. Noreena has a PhD from Cambridge University and an MBA from the Wharton School of the University of Pennsylvania. She is a Visiting Professor at University College London.
Her thoughtfully tailored keynote speeches combine a deep analytical understanding of global trends, threats and opportunities with practical solutions for how to make smarter decisions in a complex world. Noreena leaves her audience with a clearer vision for the future, arming them with better strategies that can prepare an organisation for the future, and also inspiring them.
Popular topics: The Future of Work | The Age of Radical Uncertainty: Winning in an Age of Technological, Geopolitical, Economic and Demographic Disruption | The Robots are Coming: Thriving in an Age of Digital Disruption, Artificial Intelligence, and Cyber Hacking | From Brexit to Trump: Managing the New Geopolitical and Economic Landscape | How to Make Smart Decisions in a Complex World | Generation K: How to Engage the Next Generation of Consumers and Employees
Growth / Development | Society / Future | Technology / Digitalization
Anil Gupta
Annastiina Hintsa
Karen Moloney
Tomi Kaukinen
Graeme Codrington
Anders Sorman-Nilsson
Catarina Rolfsdotter-Jansson
Shaun Smith
Micael Hermansson
Jim Lawless
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Terms and Conditions Mystery Rooms Escape Online Games
This document, through its content, makes available to customers the terms and conditions for participation in the games organized by Mystery Rooms Escape Online Games. In order to book a game and to participate in Mystery Rooms Escape games, it is necessary to explicitly and irrevocably accept the present terms and conditions.
1. In order to attend to Mystery Rooms Escape games, it is necessary to book a game interval that is available for the date, time and room you have chosen. To fulfill a reservation you need: the name of the contact person, a valid email address and a valid contact phone number. This information is required and used to confirm the reservation, to communicate booking details, to inform each other of any changes, to make any necessary communication between the organizers of the games and the participants for the good organization and development of the games and afterwards the game / games reserved for sending any photos made to the participants and / or billing documents corresponding to the games played. When all the mentioned correspondence related to the games attended is finalized, you can ask us to delete your personal details (name, phone number and e-mail address) by writing an email at: mystery@roomsescape.ro.
2. Mystery Rooms Escape games are based on attention, brainpower and teamwork and do not require any special skills or knowledge. Puzzles and codes solutions do not involve alteration of furniture, heating, lighting or surveillance.
3. In order for the booking to be fulfilled, the game is to be paid for in advance. The cost depends on the number of zoom connections. The game will not start if the number of players connected via separate zoom connection exceeds the number of paid connections.
4. The Game Master will not act on your directives unconditinally. Damage to objects in the room or to the room itself during the game is not allowed. The GameMastes is a "passive" member of your team, meaning that he/she can remind you common sense guidance and rules and also could prove helpful to provide you valuable small hints for you to advance through the game.
6. The team can should not be larger than 7-8 players, no matter the number of connections.. Children aged 12 or under must be accompanied by at least an adult in the same location.
7. Escape room games are not allowed under the influence of alcoholic beverages or narcotics. In such cases, the organizers reserve the right to immediately cancel or discontinue the game without refund.
8. Video recording or taking pictures during the game is (kindly!) forbidden. In the situation when this rule is not respected, the game will be immediately interrupted by the organizers without reimbursement.
9. We allow cancellations with refund up to 24 hours before your game. You can also reschedule a booking up to 24 hours before your game for no charge.
10. It is recommended to join the game/link 15 minutes before the appointment time to participate in a briefing on the proceedings of the game and rules of conduct. In case you will be delayed, the briefing will still be sustained, and the playing time might be shortened in order to respect the booking interval. Attending the game is allowed only all participants have attended the briefing.
In case of non-compliance with these terms and conditions, or with the rules of conduct explained in the training, the game master(s) reserve the right to cancel the game at any time with no refund.
Testimonials Mystery Rooms Escape
Raul C
It was hard to find an available spot to book this weekend. But it was all worth it! Let me know when you'll launch the Secret, to book in advance :)
Moniq
Heist was my first online escape game experience and it was a very enjoyable one! The game is well thought and fun, the 360 tour and inventory are nice and useful addons
I've tested Heist virtual escape room game before it was open for public and I loved it, it was very entertaining! I didn't expect to very much like an onine game, as I've played a lot of escape games, but I must say the onlne escape game is nothing less, just different!
A pleasant and fun video live experience. As soon as the action began, we forgot that we were in front of a computer, it felt incredibly real!
These virtual games are something new in terms of entertainment. I love the concept if it is well implemented like here, I can see its potential develop for the future as it is fun and exciting. They are also appropriate for teambuilding!
© 2014 www.mysteryroom.ro
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The Hot Countries (Hardcover)
By Timothy Hallinan
Unavailable to Order
This is book number 7 in the Poke Rafferty Thrillers series.
#1: A Nail Through the Heart (Poke Rafferty Thriller #1) (Compact Disc): $19.99
#2: The Fourth Watcher (Poke Rafferty Thriller #2) (MP3 CD): Unavailable to Order
#3: Breathing Water (Poke Rafferty Thriller #3) (Compact Disc): Unavailable to Order
#4: The Queen of Patpong (Poke Rafferty Thriller #4) (MP3 CD): Unavailable to Order
#5: The Fear Artist (Poke Rafferty Thriller #5) (Compact Disc): Unavailable to Order
#6: For the Dead (Compact Disc): Unavailable to Order
Kobo eBook (October 5th, 2015): $9.99
Paperback (September 6th, 2016): $17.55
Back when Poke Rafferty first arrived in Bangkok to write a travel guide, some of the old-timers in the Expat Bar on Patpong Road helped him make sense of the city. Now these men--many of whom have been living in Southeast Asia since the Vietnam War--have grown old and, in some cases, frail. When a talkative stranger named Arthur Varney turns up at the Expat Bar, they accept him without suspicion, failing to see that he's actually using them to get to Poke.
Varney wants two things: money Poke doesn't have and a person Poke is unwilling to hand over. It quickly becomes apparent that there's nothing Varney won't do to secure his goals. As his actions threaten the foundation of Poke's life in Thailand, the aging men of the Expat Bar discover that they might still be a force to reckon with.
Timothy Hallinan has been nominated for the Edgar, Nero, Shamus, and Macavity awards. He is the author of eighteen widely praised books, including The Fear Artist, For the Dead, Crashed, Little Elvises, The Fame Thief, King Maybe, Fields Where They Lay, and Herbie's Game, which won the Lefty Award for Best Humorous Mystery. After years of working in the television and music industries, he now writes full-time. He divides his time between California and Thailand.
Publisher: Soho Crime
Publication Date: October 6th, 2015
Series: Poke Rafferty Thrillers
Thrillers - General
Mystery & Detective - International Mystery & Crime
Mystery & Detective - Amateur Sleuth
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Published by: National Association of Estate Planners & Councils
The centralized location for best-in-class thought
leadership for the estate planning professional
Professional Designations
NAEPC Webinars:
Wednesday, January 20, 2021 at 3:00pm - 4:30pm ET - Growing Your Business and Network in a Virtual World: A Multidisciplinary Panel Discussion
Source: The Robert G. Alexander Webinar Series
P… Read more
Panelists - Dean DeLisle, Founder and CEO, Forward Progress; Thomas M. Forrest, TO, AEP® (Distinguished); Bronwyn L. Martin, MBA, ChFC®, CLU®, CLTC®, CRPC®, CFS®, CMFC®, AEP®, LACP, AIF®, CFS; Ginger F. Mlakar, JD, CPA, AEP®; Gregory E. Sellers, CPA, AEP®
Has the global health crisis and the acceleration of an online environment changed the way you market your services and advise your clients? Do you have the technological tools to communicate effectively with your current network? Are you looking for ways to expand your reach? Attend this unique multi-disciplinary panel discussion to learn strategies for interacting with your clients in the rapidly growing virtual space from experts in the technology, legal, trust, insurance and financial planning, philanthropic, and accounting practice areas. Those who are unable to attend on the live date and time are welcome to register and on-demand access will automatically be sent so you can watch the program at your leisure.
Moderator - Martin M. Shenkman, CPA/PFS, MBA, JD, AEP® (Distinguished)
Mr. Shenkman is an attorney in private practice in estate and tax planning, planning for closely held businesses, and estate administration in Fort Lee, New Jersey and New York City. He is the author of 42 books and more than 1,000 articles. Editorial Board Member of Trusts & Estates Magazine, CCH (Wolter’s Kluwer), and the Matrimonial Strategist. Has previously served on the editorial board of many other tax, estate and real estate publications.
Dean DeLisle, Founder and CEO, Forward Progress
Founder and CEO of Forward Progress serving over 2,000 corporate clients over the past 15 years. In 2012 Dean created and released a Social Influencer Development Platform known as Social Jack. Dean is host of his own Podcast, Influence Factory, and has written, FIRST, The Street Guide to Digital Business Influence which gives the reader proven essential steps and tools to develop thought leadership and recognition in their industry. His company has produced over 5,000 virtual events and webcasts.
Thomas M. Forrest, TO, AEP® (Distinguished)
President and CEO of U.S. Trust Company of Delaware. Tom is past President and founder of the Personal Trust Division for Charles Schwab Bank in Wilmington, Delaware. Mr. Forrest assisted the IRS with the development of fiduciary income tax returns on magnetic media. He has lectured to professional groups on a variety of tax and estate planning topics at numerous meetings and seminars around the country.
Bronwyn L. Martin, MBA, ChFC®, CLU®, CLTC®, CRPC®, CFS®, CMFC®, AEP®, LACP, AIF®, CFS
Bronwyn Martin has been doing comprehensive financial planning for over 20 years. Bronwyn has 2 offices in 2 different states, clients throughout the US, and a virtual staff of 5. She is currently serving as a member of the National Association of Estate Planners & Councils Board of Directors.
Ginger F. Mlakar, JD, CPA, AEP®
Ginger Mlakar serves as in-house legal counsel and oversees the donor stewardship program for the Cleveland Foundation. She has been named among the Best Lawyers in America and the Top 50 Female Ohio Super Lawyers List by Law and Politics magazine. She is currently serving as a member of the National Association of Estate Planners & Councils Board of Directors.
Gregory E. Sellers, CPA, AEP®
Greg is a Member in the Tax Division of Warren Averett, LLC, a leader of the firm’s Estate and Trust Service Area, and he has been serving clients for 35 years. Greg also served on the NAEPC Board of Directors and is a past president of NAEPC and the Montgomery (AL) Estate Planning Council.
Please note this is a special 90-minute presentation.
REGISTER HERE for the individual program. To purchase the 2021 webinar series, please click HERE.
Wednesday, February 10, 2021 at 3:00pm - 4:00pm ET - Post-Election Estate Planning
D… Read more
Wednesday, March 10, 2021 at 3:00pm - 4:00pm ET - Diversity, Equity and Inclusion
Wednesday, April 21, 2021 at 3:00pm - 4:00pm ET - TBD
Wednesday, May 12, 2021 at 3:00pm - 4:00pm ET - 529 Planning
Wednesday, June 9, 2021 at 3:00pm - 4:00pm ET - Tax-Smart Charitable Giving, Especially with Retirement Assets
Program details coming soon.
Christopher Hoyt is a Professor of Law at the University of Missouri (Kansas City) School of Law where he teaches courses in the area of federal income taxation, charitable organizations and retirement plans.
Previously, he was with the law firm of Spencer, Fane, Britt & Browne in Kansas City, Missouri. He received an undergraduate degree in economics from Northwestern University and he received dual law and accounting degrees from the University of Wisconsin.
Professor Hoyt is the Vice- Chair of the RPTE Charitable Group and he serves on the editorial board of Trusts and Estates magazine. He is an ACTEC fellow and has been designated by his peers as a "Best Lawyer". He was elected to the Estate Planning Hall of Fame by the National Association of Estate Planners & Councils.
Wednesday, July 14, 2021 at 3:00pm - 4:00pm ET - TBD
Wednesday, August 11, 2021 at 3:00pm - 4:00pm ET - TBD
Wednesday, September 8, 2021 at 3:00pm - 4:00pm ET - TBD
Wednesday, October 13, 2021 at 3:00pm - 4:00pm ET - TBD
Issue 27 – October, 2017
NAEPC Journal of Estate & Tax Planning
Editor’s Note: Forget “Must Love Dogs” – Go with “Must Love DSUE”
No dogs were injured in the writing of this note.
Author: Susan P. Rounds, JD, CPA, LL.M., AEP®, TEP
Accredited Estate Planner® Designee – Top Pick (See previous top picks)
Checklist: Annual Review (PDF file)
This cool tool provides a quick overview of the suggested areas to review with your estate planning clients each year.
Author: Martin M. Shenkman, CPA, MBA, PFS, AEP® (Distinguished), JD
Crowdsource Funding to Help Victims of the Las Vegas Massacre (PDF file)
This just in! The issues surrounding crowdfunding are numerous and complex. In order to provide some on-the-spot technical guidance in an area with little law and less guidance, these “Masters Among Us” quickly developed this road map to motivate quick and compassionate action in the wake of this and other charitable causes you and your clients are considering.
Authors: Martin M. Shenkman, CPA, MBA, PFS, AEP® (Distinguished), JD, Bernard A. Krooks, Esq., and Jonathan G. Blattmachr, Esq.
A First Look at Congress’ Tax Reform Blueprint – What Advisors Need to Know Now to Better Inform Their Clients (PDF file)
This indispensible commentary not only explains the Unified Framework for Fixing our Broken Tax Code, but it goes much deeper and analyzes the potential issues and planning opportunities that may arise.
Reproduced courtesy of Leimberg Information Services, Inc. (LISI)
Authors: Robert S. Keebler, CPA/PFS, MST, AEP (Distinguished) and Jim Magner, JD, CLU®, ChFC®
Innovative Trust Designs Better Serve Inheritors (PDF file)
Why grant only three wishes when you can grant them all? Learn what is on every estate planning client’s “wish list” and which drafting provisions can accomplish these universal client aims.
Originally published in the June 2017 issue of Estate Planning. Reproduced with permission.
Authors: Richard Oshins, MBA, LL.M., AEP (Distinguished) and Paul Hood, Jr., JD, LL.M.
Planning in Uncertain Times – Part III (PDF file)
The final segment in the trilogy Planning in Uncertain Times continues the discussion of the cost of delaying planning by incorporating an illustration utilizing dynastic planning and life insurance.
Author: Robert W. Finnegan, JD, CLU®
Balancing Collaboration With the Attorney-Client Privilege (PDF file)
Collaboration is frequently recognized as a best practice. The authors highlight the need to maintain confidentiality in this framework and examine the importance of striking a balance between increased collaboration and preserving the attorney-client privilege.
Originally published in the March 2017 issue of Trusts & Estates. Reprinted by permission.
Authors: Charles Douglas JD, CFP®, CAP®, AEP®, Judi Cunningham MA, FEA and Jennifer Devine Odom, JD
Complacency. Motivation. Retention. (PDF file)
Looking for ways to engage clients in the financial planning process? Understand the intrinsic and extrinsic motivational factors and techniques advisors can use to garner good results, client retention, and bonus – an increased probability of referrals.
Author: Bronwyn L. Martin, PhD, MBA, ChFC®, CLU®, AEP®, CRPC®, CFS®, CMFC®, CLTC®
High Performance Organizational Teams (PDF file)
As the world of estate planning becomes increasingly interdependent, and many of us strive to accomplish our client’s objectives through multi-disciplinary teaming, how can we structure teams that are truly high performing? Laying out the difference between ‘groups’ and ‘teams’ and identifying the markers of an actual team and the stumbling blocks to getting there, the authors provide a roadmap that leads to true TEAMWORK.
Authors: Nancy B. Rapoport, J.D. and Charlie Douglas J.D., CFP®, CAP®, AEP®
Reviewing a Life Insurance Policy: The Owner As Pilot (PDF file)
A practical spin on a lofty topic. A handy list of 10 questions to chart your course when reviewing a life insurance policy.
Reproduced courtesy of Ultimate Estate Planner
Author: Jason Oshins, MBA
Built-in Gain Tax Liability: Defend Yourselves! (PDF file)
There is a potential value reduction for Built-in Capital Gain Tax Liability (BIGL) for certain assets owned by an estate. This detailed and technical paper takes us through the history of the case law culminating in the Estate of Richmond, which supports a value reduction based on an assumed future liquidation date of the corporation’s assets. The author lays out the valuation and accounting principles inherent in calculating the deduction and argues against using future expectations as a basis for valuation.
Author: James Lisi, CVA, MBA
Proposed Regulations Under Code §2704 Finally Die (PDF file)
Find out if they actually pulled the plug. The autopsy results for the infamous Proposed Regs under 2704.
Author: Keith Schiller, Esq.
Fees for Life Insurance Consulting? Why Would I Do That? (PDF file)
For our NAEPC Journal readers. A great question deserves a great answer. Learn about a novel phenomena in the insurance industry: Fee-based consulting.
Author: Bill Boersma, CLU®, LIC, AEP®
News Nook: A Compendium of Current Affairs
The NAEPC Journal of Estate & Tax Planning Tax Update (PDF file)
Author: Scott E. Swartz, JD, LL.M., AEP®
Tax Topics – September: “Unified Framework for Fixing Our Broken Tax Code” &August: Possible “Extenders” Bill if Tax Reform Doesn’t Pass (PDF file)
Author: Blanche Lark Christerson, JD, LL.M. (taxation)
Practical Planner Newsletter (PDF file)
NAEPC Monthly Technical Newsletter
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The following materials are published and provided by the National Association of Estate Planners & Councils (NAEPC) as part of its mission to promote excellence in estate planning by delivering exceptional resources and unsurpassed education.
The opinions expressed in this publication do not necessarily represent the opinions of NAEPC, its Officers, Board of Directors or its various committees. NAEPC does not provide legal, tax, accounting or financial advice and these materials are published solely to provide a diversity of thought and information on topics involving wealth planning, tax, estate and gift planning, estate and trust administration and philanthropy.
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Perpetual Planet
The renaissance of Riesling: five to try
After decades out of fashion, Germany’s best-known wine is back and better — as well as drier — than ever
By Fiona Beckett
Photographs By Getty
Published 9 Apr 2019, 00:03 BST, Updated 5 Nov 2020, 05:27 GMT
Church in the vineyards of Oppenheim, Germany
Photograph by Getty
Riesling. I’m wondering what image that word conjures up for you. Cheap, sweet German wine — the kind your gran used to drink? If so, you wouldn’t be alone, but you’re missing out on one of the wine world’s great pleasures.
This noble grape hasn’t always been held in such low regard. Back in the early 20th century, German riesling was regarded as a great gastronomic wine, commanding prices comparable to top Bordeaux and appreciated for its unique combination of low alcohol, sweetness and perfectly balanced acidity. But sweetness went out of fashion and, thanks to a fiendishly complicated classification system, these wines are hard to understand. Spätlese, for example, can be either dry or sweet.
Despite that, riesling is having a moment again, particularly on restaurant wine lists where it’s often a well-priced and versatile option with a selection of small plates. Even high-street retailers are increasing their ranges. Majestic reported a ‘bumper summer’ last year, with sales up 18% due to the high-quality riesling it’s been introducing from Germany and elsewhere.
It strikes me there are a couple of reasons for this — the first being the rise of two cuisines that suit riesling remarkably well — Asian and Scandinavian. With Thai, Indian and Sichuanese food, for example, the apparent sweetness of many rieslings is offset by the heat of the food. And it goes really well with the cured, smoked and pickled elements of modern Scandi cooking, too.
The other reason is that rieslings have become drier — even in Germany. That’s partly a question of climate, but also an awareness among German producers that the market is looking for less sweet styles.
Although rieslings from the Mosel still tend to be off-dry (even a kabinett can have up to 9g of residual sugar) those from warmer German regions such as Rheinhessen and the Rheingau are often bone-dry. One way to tell how dry or sweet a riesling is to look at the alcohol: under 10% and chances are it’s sweet, over 12.5% and it will generally be dry.
Other major European riesling-producing regions, such as Austria and the Alsace in France, also tend to produce drier styles, unless they’re consciously aiming for something sweet. Australia carved out a distinctive lime-streaked style in the Eden and Clare Valleys as well as pioneering the use of screw caps, which have now been widely adopted to preserve the unique quality of the fruit. In the US and Canada, slightly sweeter, more floral styles have always been popular — look out for rieslings from Washington State and the Finger Lakes region of New York.
While riesling can be drunk young, with age it develops a beguiling lime and kerosene character that’s a great deal more appealing than it sounds. People think it’s just red wine
you should cellar, but riesling keeps for years.
Five to try
Alexander Gysler Kammerton, Rheinhessen, Germany
Riesling makes lovely sparkling wine; it’s fruitier and less austere than champagne. This, from a German estate that’s run biodynamically, is a perfect aperitif. £17.50.
Trimbach 2015, Alsace, France
Alsace riesling is drier than most German ones, and this pure, powerful wine would go well with seafood. Or try it with choucroute — an Alsatian platter of cabbage with sausages and other charcuterie. £15.95.
O’Leary Walker 2013/14 Polish Hill River, Clare Valley, Australia
A gorgeous, mature riesling with a mouthwatering hit of lime, from the region of Australia best-known for its variety. Drink with Thai and other Southeast Asian salads. £12.95.
Kung Fu Girl 2016/17, Washington State, US
I love this bottle from former rock band manager Charles Smith, not just for the name and label but for its bright, fruity and refreshing taste, too. It goes really well with Indian food, or — alternatively — sushi. £13.95.
Seifried Estate Sweet Agnes 2016, Nelson, New Zealand
This is a really luscious dessert wine packed with citrus and tropical fruit. It’s ideal when paired with a sweet, such as strawberry or passion fruit pavlova. £16.29 for a half-bottle.
Follow @winematcher
As featured in Issue 4 of National Geographic Traveller Food.
SubscribePrivacy Policy(UPDATED)Terms of ServiceCookie PolicyPolicies & ProceduresContact InformationWhere to WatchConsent Management
Berlin: Bottoms up
Eat: Hamburg
Hamburg: Classical encounters
City slickers: The boldest, brightest and brashest
Hamelin: The trail of the Pied Piper
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Minnesota doctor decries censorship, says he is under investigation for COVID-19 opinions
Tuesday, July 14, 2020 by: Michael Alexander
Tags: badhealth, badmedicine, badscience, CDC, Censorship, conspiracy, coronavirus, covid-19, deaths, Fatalities, infections, medical fascism, Medical Tyranny, minnesota, mortality rate, obey, outbreak, pandemic, Scott Jensen, speech police, thought police, Tyranny, USA
Bypass censorship by sharing this link:
https://www.distributednews.com/439409.html
(Natural News) Minnesota doctor and Republican state senator Scott Jensen is now under investigation by medical authorities for voicing out his opinions about the SARS-COV2 virus, as well as the guidelines issued by the Centers for Disease Control and Prevention (CDC) on certifying COVID-19 deaths.
Jensen, who is a family physician by profession, took to social media to share that the Board of Medical Practice in Minnesota is currently investigating him for allegedly “spreading misinformation” regarding the completion of death certificates during his appearance on a news program. The so-called investigation also includes him allegedly providing what was deemed to be “reckless advice,” in which he allegedly compared COVID-19 to influenza.
“I should have seen it coming because I saw the threats on social media; I’ve seen them for the last two or three months. They didn’t agree with me. They didn’t like that I was trying to provide some context for the flu, for COVID-19,” Jensen said in a video. (Related: Expert: Actual COVID-19 deaths likely to be double the “official” numbers.)
While he has no means to identify who sent or made the complaints, he is sure that the threats came from “people in all walks of life” – including fellow physicians.
“I don’t know if they’re routinely in a political camp if they’re activists. I’ve gone online and looked at what it takes to complete a complaint that the Board of Medical Practice has to follow up on,” Jensen said. “It’s a one-page deal. You can say what you want, you could be a huge donor for the other party.”
Jensen, in an interview with KARE, noted that his situation is currently hard, especially since the licensing board is being used as a weapon.
“And then the fact that you don’t get to know your accuser. And this has nothing to do with patient care, this has to do with public comments,” he added, referring to a clause that prohibits the medical board from divulging the names of those who lodged the complaints against him.
“This is a conversation that, quite frankly, Minnesota and America have to have,” Jensen said in his KARE interview, adding that using a regulatory board to silence a person for his opinions is wrong.
One of the complaints lodged against him stems from an interview he did back in April, wherein he cited the instructions that physicians received from the Minnesota Department of Health on how to label probable COVID-19 deaths on patient death certificates.
In that interview, Jensen took particular issue with listing COVID-19 on death certificates, noting that following government instruction ?– which mandated that suspected cases be labeled as actual COVID-19 deaths – would only result in the artificial inflation of the number of deaths because fatalities from other illnesses could be lumped together with those caused by the coronavirus without undergoing actual laboratory confirmation.
The interview prompted the Minnesota Department of Health to clarify what the instructions meant, with the department assuring the public that probable COVID-19 cases will not be added to the state’s official death totals until after their confirmation. This was then confirmed by Jensen, who noted that while Minnesota is doing the death count correctly, places such as New York and other states are still overstating their actual death tolls.
Aside from his comments on the labeling of COVID-19 casualties, Jensen also faces a complaint regarding his public statements wherein he compared the mortalities caused by the COVID-19 pandemic to those caused by other factors.
“When we talk in our country of 130,000 deaths of COVID-19 and then I share with you between suicides, drug overdoses and accidents the deaths are twice that number, I think that matters,” the state senator added.
Jensen has also come under fire for his criticism of the CDC, saying in a Fox News interview that the nation’s top epidemiological agency not only mishandled the pandemic but also became a partisan organization. While he still thinks that the Board of Medical Practice does “important work” and that he has plans to “fully cooperate with them,” he still feels as though he is being targeted for his opinions.
“If this could happen to me because of my views, it could happen to anybody.”
TheEpochTimes.com
Fox9.com
KARE11.com
Previous :University students brand Lincoln a “White supremacist,” demand statue’s removal from campus
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https://www.naturalnews.com/2020-07-14-minnesota-doctor-under-investigation-for-covid-19-opinions.html
<a href="https://www.naturalnews.com/2020-07-14-minnesota-doctor-under-investigation-for-covid-19-opinions.html">Minnesota doctor decries censorship, says he is under investigation for COVID-19 opinions</a>
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What to know about Azure Arc’s hybrid-cloud server management
At it again: The FCC rolls out plans to open up yet more spectrum
NFC vs. Bluetooth LE: When to use which
4 essential edge-computing use cases
Chip maker Nvidia takes a $40B chance on Arm Holdings
Telehealth usage soars during COVID-19
New Arm processor promises smart storage
VMware certifications, virtualization skills get a boost from pandemic
A quiet social network makes China happy in recent crackdown
China to give jail sentences for Internet users found guilty of online...
China Telecom's YiChat takes aim at Tencent's WeChat
China to tighten hold on Internet, citing worries about nation's stability
In recent months, China has been cracking down on Internet users for spreading rumors
China is moving to tighten its grip over social networking services even more, citing possible threats to stability.
On Friday, Chinese authorities released a new blueprint for the country's future that covered economic and social reforms including loosening the nation's decades old one-child policy. But in the online space, the government showed no signs of shifting gears in its vast censorship of the Internet.
The government instead pointed to problems with its existing system to manage the flow of online information. Currently, there are too many different overseeing departments, resulting in inconsistencies and a lack of efficiency, the government said in a posting, explaining the reforms.
"At the same time, due to the rise of online media, the Internet regulatory systems that manage the media and the industry are falling far behind to catch up with the new changes," the post stated.
The government referred to the growing popularity of Chinese social networking and instant messaging tools as a major worry. The services can rapidly disseminate information and mobilize society, the posting said.
The authorities specifically mentioned Weixin, a mobile chatting app developed by local Internet giant Tencent. The app has taken China by storm, and boasts over 200 million monthly average users. Outside of the country, the app is better known as WeChat.
To make the Internet "more secure," China plans to bolster its regulatory systems, and increase the scope of their legal authority, the government said without offering further details.
China has already gained notoriety for its strict censorship of the Internet, and has blocked foreign sites such as YouTube, Facebook and Twitter. Local social networking services, however, continue to operate, but self-censor content by sometimes deleting politically sensitive or anti-government posts.
Despite that, in recent months Chinese authorities have been cracking down on Internet users for allegedly fabricating rumors online. In September, China said it would hand out jail sentences to users found guilty.
Michael Kan covers security for IDG News Service.
IT Salary Survey: The results are in
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Outswinger
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The Information and Broadcasting Ministry has issued notice to Amazon Prime, seeking its response to the complaints against its web series 'Tandav' starring Saif...
Home India First tribal woman takes oath as Jharkhand governor
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First tribal woman takes oath as Jharkhand governor
By NewsGram Staff Writer
On Monday, Draupadi Murmu took oath as the ninth governor of Jharkhan at Raj Bhawan in front of Jharkhand High Court Chief Justice Virendra Singh. She succeeded Syed Ahmad, who has been shifted to Manipur.
The ceremony was attended by many people, including the Chief Minister Raghubar Das.
Murmu started her political career in the year 2000 by winning the election from Odisha’s Mayurbanj district. She was re-elected in 2005 from the same assembly and became a minister of state for finance and transport.
She graduated from R.B. Women’s College Bhubaneshwar in 1979. Thereafter, she worked as a clerk in the state secretariat for some years before joining politics.
She was also the vice-president of Rairangpur Notified Area Council from 1996-98. In May 2013, she was appointed as the district president of BJP in Mayurbhanj.
Draupadi Murmu
Female Governor
Tribal Woman
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Community halls in closure threat
COMMUNITY halls across the borough could close if voluntary groups are not prepared to take over their management.
Robert Cumber
Council contractor Fusion is currently responsible for the four halls in question, but civic centre leaders claim handing control to residents already using the venues would save them £288,000 a year.
The move is part of plans to cut next year's council budget by £18million after central government funding was slashed.
If the council cannot find suitable 'partners' to run the halls, they may have to close.
The venues at risk are: * Feltham Assembly Hall * Heston Village Hall * Isleworth Public Hall * Montague Hall, Hounslow.
Councillor Pritam Grewal, Hounslow Council's lead member for leisure and wellbeing, said: "To do this in a sustainable way, we know that we would need to provide support to any organisation or group to take on the operation of this service.
"We also know that the level and type of support to do this will vary from hall to hall. We
would expect that any offer or proposal would need to protect existing use and user groups and ensure the halls continue to provide a service for the communities they serve."
Individual residents and organisations who are interested in taking on the operation of the hall they use should email communityhallconsult@ hounslow.gov.uk.
Residents can have their say as part of the wider consultation on next year's budget at www.hounslow.gov.uk.
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Steve Martin shares ‘good news/bad news’ about COVID vaccination
Lawmakers pass bill allowing more cameras to ticket drivers blocking NYC bus lanes
By Clayton Guse
An MTA bus is pictured in a bus lane. (Tomas E. Gaston/for New York Daily News)
Stay clear of the bus, please.
State lawmakers threw New York City bus riders a bone Friday when they passed legislation that allows city and Metropolitan Transportation Authority officials to expand the number of automated cameras used to enforce bus lanes.
Bus lane cameras are currently limited to 16 routes around the city, which doesn’t resonate with Mayor de Blasio’s plan to paint new bus lanes on streets in the five boroughs.
The measure was tucked into a must-pass spending bill that Gov. Cuomo is expected to sign, giving city officials the green light to better enforce the right-of-way for buses and speed up service for 2 million daily riders.
The legislation removes time restrictions for bus lane enforcement and establishes fines for cars that double-park in or otherwise obstruct the lanes. Currently, cameras are only allowed to be active from 6 a.m. to 10 p.m.
[More New York] Brooklyn cop who killed man in 2016 road rage incident will face internal NYPD discipline trial »
Drivers will be hit with a $50 fine for their first bus-blocking offense in a given year, $100 for a second offense, $200 for a third and $250 for additional offenses. Warning notices will be issued for the first 60 days after a bus lane camera is placed on a route.
The new measures are the latest victory for New York’s transit advocates, who have led the charge to make buses a better alternative for commuters.
Get updates on the coronavirus pandemic and other news as it happens with our free breaking news email alerts.
“We know bus lanes work, but when cars illegally park or drive in dedicated bus lanes, they cause major delays for buses and traffic jams for other vehicles,” said Tri-State Transportation Campaign Executive Director NIck Sifuentes. “Now, that illegal activity will be regularly and fairly discouraged.”
Riders Alliance spokesman Danny Pearlstein called it a “shot in the arm” for bus service. “I think this is reflective of a sea change in Albany for transit riders, especially after we had congestion pricing in the budget to fix the subway,” Pearlstein said.
Assemblywoman Nily Rozic (D-Queens) was one of the chief sponsor’s of the bill, and said the new regulations should help bring commuters back to buses after years of declining ridership.
“People are frustrated with the subways, people are frustrated with congestion,” said Rozic. “I think clearing the lanes will mitigate traffic congestion and improve people’s perception and experience with New York City buses.”
City Department of Transportation spokesman Scott Gastel said the next step is to identify routes where expanded enforcement will have the greatest effect on service.
[More New York] MTA ignored white supervisor’s assault of Black attorney: suit »
The bill also clears the way for the MTA to expand a pilot program that puts automated enforcement cameras on buses. They’re currently on the B44 and B48 select bus routes, and will be added to the new M14 select bus route when it starts next month.
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Patient advice and liaison service
← Looking after your health this Easter
CCG Governing Body Vacancies →
by Matt Thompson | April 2, 2019 · 2:55 pm
Healthy Hearts seeks to tackle the region’s biggest killer
Greater Huddersfield and North Kirklees CCGs are joining healthcare providers across the region to tackle the area’s biggest killer. The West Yorkshire and Harrogate’s Healthy Hearts programme aims to help reduce the impact of heart disease and prevent the number of heart-related illnesses, including heart attacks, stoke and diabetes.
The programme, created by the West Yorkshire and Harrogate Health Care Partnership, aims to reduce the number of people in the region affected by heart disease by 10% by 2021, meaning 1,100 fewer cardiovascular disease (CVD) incidents by 2021.
Dr Steve Ollerton, local GP and Chair of NHS Greater Huddersfield CCG said: “The nine Clinical Commissioning Groups within the West Yorkshire and Harrogate Health Care Partnership have committed to tackling CVD and diabetes. We’ve been working together over the last year to share the learning from a number of local projects, including Bradford Healthy Hearts, to develop our own project for the region.”
Dr Youssef Beaini, clinical lead for the programme across West Yorkshire and Harrogate said: “We’re delivering Healthy Hearts in three phases. Phase one sees us working to help local GP’s identify patients with undiagnosed high blood pressure (hypertension), and we estimate there may be up to 18,000 across the region, which can often be an indicator of cardiovascular disease.
“We also estimate that there’s a group of nearly 40,000 patients across the region, who’ve already been diagnosed with hypertension, that will benefit from through simple improvements to their existing medication. In fact, we believe that phase one alone will prevent 285 heart attacks and 421 strokes across West Yorkshire and Harrogate, saving the NHS £8m.”
Dr David Kelly, local GP and Chair of NHS North Kirklees CCG added: “It’s also important that people realise there’s a lot they can do to reduce the risk factors that lead to cardiovascular disease, such as being overweight, smoking, drinking and having an unhealthy diet. It’s never too late to start looking after your heart. The Healthy Hearts programme will help patients make the kinds of lifestyle changes needed to stay healthy.”
Phase one of Healthy Hearts went live this month. Phase two, due to begin in autumn of 2019, will see an emphasis on lipid/ cholesterol management and phase three, set to begin in 2020, will see a concentration on glycaemic control in diabetes.
Further information about Healthy Hearts programme can be found by visiting https://www.westyorkshireandharrogatehealthyhearts.co.uk/
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Vaccines teach your immune system how to create antibodies that protect you from disease
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Process basic customer account enquiries
This learning object contains activities on processing customer account enquiries. Includes understanding the enquiry, accessing and providing information and escalating a call.
Will There Be QE3, QE4, QE5...?
Recently, Ben Bernanke indicated that Quantitative Easing II (QE2) might be followed by QE3, etc. In an interview at the beginning of December, Bernanke was asked, "Do you anticipate a scenario in which you would commit to more than $600 billion?"
Bernanke's answer was startling. "Oh, it's certainly possible," he said. "And again, it depends on the efficacy of the program.
Hello Panwapa Island!
A young curious monster named Azibo arrives on Panwapa Island, eager to make friends. But some of the animals that live on the island have never known a monster before-and they don't want to start now. If you would like to add more questions or share ideas about how you use Panwapa with your students, create or join a Panwapa group using Curriki's group tools. (Under the Member Community tab in the navigation bar on the left, click "browse groups" or "create a new group.") Run time 10:34.
Nature by Numbers
A movie inspired on numbers, geometry and nature. Music helps sets the tone. A great way to get students interested in geometry and see it in nature. Would be a great start to a research project or sharing idea of where there are other examples.
Duke Basketball Game Broadcast in Chinese
On January 15, 2011, the Duke Men's Basketball game against the University of Virginia was broadcast live over the web in Mandarin Chinese. The Duke student announcers for the broadcast were Jesse Sun, Yunze Chen and John Sheng. It was the first time in ACC history that a game has been broadcast in Chinese. Learn more at http://news.duke.edu/2011/01/basketball_chinese.html.
How to Make Math Meaningful
Making math meaningful is about relaying everyday events to concepts like money and current events. Foster a real-world connection with the use of mathematics using assistance from a math teacher.
I Am a C-H-R-I-S-T-I-A-N
Bomb Dropping Sea Worms/Rice Snorkels/Cell Battles
Shows video of deep sea worms and a defensive mechanism that allows the worm to release bioluminescent tissue. Also discusses adaptation of rice to avoid drowning and host cell infections by bacteria. This video could be used on animal adaptations and defenses as well as plant adaptations.
December 2010 Monthly Update on Global Capitalism
Author(s): jenmhill
Maoist rebels 'ready for peace'
Maoist rebels in the Philippines are optimistic about upcoming peace talks with government officials, but critics say it could be a ploy.
Kitchen Culture, October 28, 2010
The exhibition Counter Space: Design and the Modern Kitchen explores the twentieth-century transformation of the kitchen as a bridgehead of modern thinking in the domestic sphere—a testing ground for new materials, technologies, and power sources, where designers could also exercise growing modern concerns for hygiene, efficiency, and the rational organization of space. This special dinner features live music, performance art, a napkin-folding workshop, and background on the exhibition, as wel
CI Days 2010 at Purdue Using CI at Purdue
CI Days 2010 at Purdue Using CI at Purdue December 8, 2010 featuring Gabriela Weaver, Chemistry; David Salt, Horticulture and Landscape Architecture, and Matt Potrawski, Purdue Center for Prediction of Reliability, Integrity and Survivability of Microsystems.
How to Use Quotations in Essays
How to Use Quotations in Essays. Part of the series: How to Write an Essay. Learn how to include quotations in the introduction of an essay in this one-minute (and 7 seconds) video on writing essays.
5 new lines for Beijing's subway
Five new subway lines open in Beijing, with more planned as the capital struggles to balance transportation gridlock and residents' desire for cars.
Wise International Decisions: The Bigger, the Wiser? (audio)
La sagesse collective : principes et mécanismes
Colloque des 22-23 mai 2008, organisé par l'Institut du Monde Contemporain du Collège de France, sous la direction du Professeur Jon Elster.
Intervention de Ariel Colonomos, CNRS, CERI, 23 mai 2008
When he makes strategic choices, the Prince favors prudence. This is one of the basic conclusions of the realist school of international relations. Although this is highly debatable, classical realists consider that
A look inside a feed mill
enChanting Musical Artifacts in Unlikely Places: Rare Resources in MIT’s Lewis Music Library
There are times when it’s necessary to judge a book by its cover, or a single page, because that’s all that remains. Michael Scott Cuthbert and Nancy Schrock reveal some treasures from MIT’s early music collection which, while often incomplete or damaged, sing volumes about their origins and use.
006 Bilingual Aesop
La Hora - 2.08
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Astro-Venture Astronomy Educator's Guide
Astro-Venture is an educational, interactive, multimedia Web environment highlighting NASA careers and astrobiology research in the areas of Astronomy, Geology, Biology and Atmospheric Sciences. Students in grades 5-8 role play NASA occupations and use scientific inquiry, as they search for and design a planet with the necessary characteristics for human habitation.
Mars 2003: Closest Approach lithograph and associated classroom activity
The two images of Mars, taken 11 hours apart with NASA's Hubble Space Telescope, reveal two nearly opposite sides of Mars. Hubble snapped these photos as the red planet was making its closest approach to Earth in nearly 60,000 years. Prominent features visible on the images are labeled on a separate illustration. In Search of - Planet Mars is the educational activity that accompanies this lithograph.
Cyanobacteria Health Page
This Centers for Disease Control and Prevention (CDC) Health Studies page focuses on cyanobacteria, single-celled organisms thought to be the origin of plants. Cyanobacteria live in fresh, brackish, or marine water and are of concern to the CDC and Environmental Protection Agency (EPA) because some can form harmful blooms that deplete the oxygen and block sunlight that other organisms need to live. They can also produce powerful toxins that affect the brain and liver of animals and humans. This
Historical Thinking Matters
For too many Americans, the history class in Ferris Bueller’s Day Off (remember the teacher’s plaintive question, “anyone, anyone?”) is all too familiar. Our approach is meant to challenge this false and familiar image of history: understanding and reconstructing the past requires ways of thinking, reading, and questioning much more engaging and challenging than mere memorization. Teaching in a way that differs from your own schooling experience is not necessarily easy to imagine, let a
This introductory course defines biology and its relationship to other sciences. It examines the overarching theories of life from biological research and also explores the fundamental concepts and principles of the study of living organisms and their interaction with the environment. Learners will examine how life is organized into hierarchical levels; how living organisms use and produce energy; how life grows, develops, and reproduces; how life responds to the environment to maintain internal
"Analyzing Projects and Organizations, Fall 2009"
"This course teaches students how to understand the rationality behind how organizations and their programs behave, and to be comfortable and analytical with a live organization. It thereby builds analytic skills for evaluating programs and projects, organizations, and environments. It draws on the literature of the sociology of organizations, political science, public administration, and historical experience-and is based on both developing-country and developed-country experience."
Author(s): Tendler, Judith
BEN: BiosciEdNet
This site provides access to more than 4,000 reviewed resources covering 76 biological science topics: agriculture, anatomy, bacteriology, biochemistry, biodiversity, biotechnology, botany, cardiology, cell biology, ecology, environment, evolution, genetics, geography, human biology, immunology, marine biology, microbiology, molecular biology, neurobiology, pathology, pharmacology, physiology, public health, respiratory biology, soil biology, virology, zoology, and others. Registration required.
Initiation à la Programmation « par l'exemple » : concepts, environnement, et étude d'utilité
La programmation, depuis ses débuts, a toujours été vue comme une discipline difficile à apprendre et à enseigner. Même de nos jours, j. Kaasböll rapporte que les taux d'échec ou d'abandon aux cours d'initiation à la programmation en premier cycle universitaire varient de 25 à 80% de part le monde [KAASBOLL 02]. Dans le même temps, l'importance qu'a acquis l' informatique comme outil d'analyse ou de simulation dans les sciences expérimentales confère au problème de l'initiation à
Author(s): Guibert Nicolas,Guittet Laurent,Girard Patrick
The conditions of learning in networks
This paper discusses the metaphor of networks in relation to networked learning and how the conditions that apply in networked environments might affect networked learning. The paper considers recent advances in the study of networks and how insights from this work might affect the understanding of networked learning. It focuses in particular on two aspects of networks, the strength of weak links and the place of non-human elements in the network. In terms of networked learning it examines the r
Author(s): Jones Christopher
Didactique computationnelle,évocation d'un projet de recherche
Le domaine de recherche que constitue la modélisation informatique des processus didactiques est une extension naturelle des travaux engagés pour la construction d'une théorie des situations didactiques. Le passage à une modélisation formelle serait significatif de la maturité de la théorie, de sa capacité à expliciter les phénomènes qui l'occupent en vue d'un calcul assez explicite et rigoureux pour avancer dans l'évaluation de son caractère prédictif. L'enjeu théorique de la mod
Author(s): Balacheff Nicolas
GRID Technologies => 'Education' = 'Distance Education'
This paper discusses the new possibilities that Grid technologies create in education, presents current learning paradigms and makes a prediction about the way in which Grid technologies may affect the future of education. The case of the Hellenic Open University (HOU) is presented and the current educational technologies and tools used are illustrated. The paper also presents a scenario for the utilization of Grid technologies at HOU and discusses the challenges that such infrastructure create
Author(s): Xenos Michalis,Vassiliadis Bill,Skodras Athanassio
Adaptive eLearning and the Learning GRID
One important aim of LeGE-WG is the integration of new eLearning methodologies into Learning Grid technology. A central issue in these new eLearning methodologies is the concept of individualised and personalised learning to be realised by adaptive tutoring systems. The adaptivity of such systems goes far beyond adapting to the users' preferences with respect to the user interface; in co-operation between computer science, psychology, and pedagogy, systems adapting, e.g., to the individual lear
Author(s): Hockemeyer Cord,Albert Dietrich
Movement Music Medley
This collection of songs and images highlights the role of music in the Civil Rights movement.
"The Greatest Tyrant in the State of Pennsylvania": A Late Nineteenth-Century Rail Worker Describes
Although publicists for the Gilded Age corporations celebrated efficiency and the science of management, their employees did not always join the celebration. What looked like careful and disciplined management from one perspective was often viewed as petty tyranny from below. While some workers assailed upper management for this abuse others experienced the tyranny more directly in their day-to-day work lives. In this transcript taken from testimony before the U. S. House of Representatives in t
"The Baby Was Made 'Delegate No. 800'": Frances Willard Meets Elizabeth Rodgers in the 1880s
The commitment of the Knights of Labor to equality for women was more than rhetorical, as seen in the career of Elizabeth Rodgers, the Master Workman, or head, of the organization's giant Chicago District No. 24. This 1889 portrait of Rodgers, offered by leading national anti-liquor activist Frances Willard, underscored the desire on the part of many Knights, both men and women, to connect the struggle for labor reform with a broader vision that included vehement opposition to liquor. It also sh
Culturing Bacteria
An articulate presentation that includes several engage produced units that provide scripted photographic illustrations of microbiological techniques used in the culturing of bacteria. The elements included are: Dispensing a broth aseptically; Plating out a broth for single colonies; Assessing the degree of contamination in the laboratory; Separation of mixtures of bacteria; Inoculation of a broth culture. Each of these elements is contained as an individual unit in the zip file. Please note, th
Author(s): Dr John Heritage and Dr Sue Bickerdike, University
Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales,http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
"Nobody Would Eat Kraut": Lola Gamble Clyde on Anti-German Sentiment in Idaho During World War I
When the United States went to war against Germany in 1917, German Americans faced vicious and unfair attacks on their loyalty. Many anti-German incidents were not recorded, but they lived on powerfully in people's memories. In this 1976 interview, Lola Gamble Clyde, the daughter of an Irish-born Presbyterian minister and a teenager during World War I, described the "hysteria" that faced German Americans in rural Latah County, Idaho.
Over the course of several lessons, this lesson plan deals with the consequences of damming in the Grand Canyon area. Students act as scientists investigating the damming of the Colorado River by the Glen Canyon dam and experimental flooding that took place in 1996. They then write a proposal as to whether or not more experimental flooding should be done on the area considering the ecological effects. This topic has great potential for an Earth Systems Science class, as the consequences of dammi
India's Non-Nuclear Course
Chandra Shekhar Jha was India's foreign secretary from 1965 to 1967. In this video segment, Jha explains why India cannot exclude the future possibility of owning nuclear weapons. The key to disarmament, he insists, rests with the nuclear nations that are 'adding to their stockpiles' and 'preparing for war. 'Jha's interview conducted for War and Peace in the Nuclear Age: 'The Haves and Have-Nots' begins with his recollections of his devastating post-war tour of Japan with Prime Minister Jawaharl
Pale Cool, Pale Warm
A series of still images of dancers performing a solo, duet, trio, and quartet are edited together to create the suggestion of movement. John Budde provided the concept and the photography and Elizabeth Keene provided the choreography. An ambient score by composer Julie Weber accompanies the piece. This work was broadcast as an episode of "'Dance for Camera' with 'District 1.''Dance for Camera' was the earliest series created by the Dance Workshop, which was coordinated at the time by Nancy Maso
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Safian, Cambridge Student - 60 Second Impressions, GEEMA Summer School
Each year we organise a number of free one-day events and summer schools aimed at encouraging Black, Asian and Minority Ethnic students to apply to the University of Cambridge. The GEEMA Summer Schools offer a taste of university life and the wide variety of courses available to study at Cambridge, including lectures, practical work and social activities. In this 1 minute film, Safian, a current Cambridge undergraduate student who worked at last year's GEEMA Summer School, explains more about
Class of '51 Remembers
Old friends and old soldiers gather for the Harvard Class of 1951 reunion.
Exploring Relationships 3 – Life Positions
In this session we are going to continue thinking about exploring relationships. We are going to look at the concepts of life positions and transactional analysis. The resource has been developed through the Learning from WOeRK project and seeks to support learning in the work place. For an overview of all related modules and resources please visit http://cpdoer.net/collections/
Author(s): Jane Stubbafield
Gullah Music
In this video segment from EGG: the arts show, visit Sapelo Island, an island in Georgia inhabited by descendants of African slaves.
Peter Frampton Hooks Up With the International Space Station
The video with audio can also be viewed here: http://1.usa.gov/nyxGJV Musician Peter Frampton introduces Expedition 28 Flight Engineer Ron Garan during a concert at the Warfield Theater in San Francisco.
Article :: Style Your Website for Multiple Devices Using Dreamweaver CS5.5
To get a site to work properly across multiple devices used to be more a challenge than it is today. For instance, Adobe Dreamweaver CS5.5 has built-in tools that help you design for multiple devices including personal computers, tablets, and phones. In this article, Adobe expert Brian Wood shows you how to use CSS3 media queries, Multiscreen Preview, and various other tools, to easily take your design and get it to work on different devices.
Nanostructures and functionalities in polymer thin films
Nanostructures and functionalities in polymer thin films, Lecture II, Azzaroni, Omar, Research Institute of Theoretical and Applied Physical Chemistry (INIFTA), Argentina
4th period Conversations
Programming Principles: Methods
Programming Principles: Methods - David Millard Keywords:java , objects , methods , overloading
Media & Public Reaction to US Credit Downgrade
Krannert School of Management Assoc. Prof. Xiaoyan Zhang analyzes the media coverage of U.S. stock instability and the public's reaction to it.
Dragon at the Door
Thunderbird School of Global Management Professor Mary Teagarden, Ph.D., talks 5 August 2011 about competition from China, a topic she will cover at the Houston Professional Speaker Series. http://www.thunderbird.edu
Phoenix Flyby
A flyby of Phoenix, from Landsat data
Author(s): Darrel Williams,Jesse Allen
Zoom Down to Manassas, and Woodbridge, VA, areas
Starting with a view of the Washington, D.C., metropolitan area, the D.C. border and the Beltway fade in. The view then shifts to Manassas and Woodbridge, Virginia, indicating urban growth with red dots. Data sets for 1973, 1980, 1985, 1990, and 1996 are presented chronologically.
Author(s): Jeffrey Masek,Stuart Snodgrass
How To Live on a Budget
This video shows how to make a budget and the importance of math in this process. The two minute presentation moves rapidly and so students may need to have it stopped to add in their own expenses and income. Good for most all students. Some ideas are a bit silly.
Huskies Unleashed - Women's Soccer - Week 1
Northeastern Athletics will debut a new behind-the-scenes video series on Thursday (Aug. 11), titled "Huskies Unleashed." The new series will provide fans with exclusive and unprecedented access to their favorite Northeastern teams. The women's soccer program will be the first team to participate in the new series, which will offer a glimpse of the team during practices, scrimmages, team meetings and workouts. Viewers also will be treated to exclusive interviews and other original content. Eac
Ford's 100 years on British roads
Aug. 17 - Ford is celebrating 100 years of producing cars in Britain by taking 10 vehicles from its century in the UK on a countrywide tour and showcasing its new parking technology, which reverse parks a car for the driver. Joanna Partridge reports
Paris Hilton: beach club designer
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1 Water as a global resource
We shall not finally defeat AIDS, tuberculosis, malaria or any of the other infectious diseases that plague the developing world until we have also won the battle for safe drinking-water, sanitation and basic health care.
(Kofi Annan, United Nations Secretary-General (2005) The International Decade for Action 2003–2015)
Freshwater is a natural resource that is vital for human survival and
Fitness freak fish climbs waterfalls
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Silicon Valley Reports, Episode 214: Rey Johnson
April 9, 1992 Publisher: KTEH Television A short piece by local Silicon Valley television station KTEH about IBM inventor Rey Johnson. Johnson was founder and director of IBM’s San Jose Research Laboratory in 1952. Tasked with developing projects that would bring West Coast engineers into IBM and create new markets, Johnson led a number of experimental research programs and supervised development of the world’s first disk drive—the IBM RAMAC (1956). The disk drive brought near-instant ran
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Textual analysis of music video
One Minute Romanian - flyer
From the makers of the award-winning online language course Coffee Break Spanish comes a new range of titles aimed at busy people who want to acquire the absolute basics of a language. One Minute Languages from the Radio Lingua Network will introduce learners to a new language from scratch. The course is made up of ten lessons and covers topics including basic greetings, introducing yourself, and dealing with language problems. You’ll also learn numbers and other useful words and phrases whi
Absolute Beginner Questions Answered by Hiroko #2 - How often should I use WATASHI WA?
Learn Japanese with JapanesePod101.com! Asking questions is a big part of learning Japanese. Every day at JapanesePod101.com, we get so many great questions from you, the listeners. And in this video series, we’ll answer those questions! Join Hiroko and get some answers! In this lesson, you’ll learn How often should I use WATASHI WA? Visit us [...]
Author(s): JapanesePod101.com
Journey to the Center of a Virus
This cartoon animation explains the four different parts of the virus (service proteins, capsid, DNA/RNA, and membrane envelope) using the analogy of a present. The video appears to be a high school project. 2:25 min.
The Eatwell Plate--A British version of the Food Groups
Charlie tells us how much of what we need to eat daily and uses a plate-shaped pie-chart to demonstrate it. Very flashy and quick-paced, like children's television. (9:54)
Comrade Corbyn: a very unlikely coup [Audio]
Speaker(s): Rosa Prince | Until recently, Jeremy Corbyn was barely known outside political circles, yet last summer he rode a wave of popular enthusiasm to win the Labour Party leadership by a landslide, with a greater mandate than any British political leader before him. So how did this very British iconoclast manage to snatch the leadership of a party he spent forty years rebelling against? Who is he and where did he come from? And what exactly happened over the space of an extraordinary summe
17.202 Graduate Seminar in American Politics II (MIT)
This is the second in a sequence of two field seminars in American politics intended for graduate students in political science, in preparation for taking the general examination in American politics. The material covered in this semester focuses on American political institutions. The readings covered here are not comprehensive, but it is sufficiently broad to give students an introduction to major empirical questions and theoretical approaches that guide the study of American political institu
Author(s): Stewart III, Charles
Checklist - Language Assistantship
This is a resource released as part of the E-Portfolio Toolkit based on experience of developing the “Year Abroad E-Portfolio”, undertaken by the School of Languages at Leeds Metropolitan University.
Author(s): Mara Fuertes-Gutiérrez,Juan Muñoz López,Janet P
2.2 Representing numbers: positive integers
A very straightforward way of finding binary codes to represent positive integers is simply to use the binary number that corresponds to each integer. This is because every positive integer in the everyday number system (known as the decimal or denary system because it uses 10 different digits) has a corresponding number in the binary number system.
As you will see later, in Section 7 of this course, just as arithmetic (addition, subtraction, etc.) can be performed on everyday denary nu
6.2 The supremacy of EU law
Whenever there is a conflict between the provisions of EU law and the provisions of the domestic (national) law of a member state, then EU law will prevail. This is a principle which was developed by the ECJ as the relationship between domestic and EU law is not clarified by treaty provisions. This is an important principle, as it ensures the proper functioning of the EU. If an EU member state had the power to annul EU law by adopting new domestic (national) law which was in conflict with the
1.2 How does it hurt?
This is a useful question because once we know the mechanism of pain sensation we can do something about alleviating it.
When tissue is injured there follows a rapid release of ‘messenger’ chemicals that stimulate the nerve endings. Electrical impulses are relayed through the nerves to the spinal column and to the brain, which registers the sensation of pain. It usually, but not always, also directs our attention to the site where the damaged tissue initiated the pain message.
Having looked at the contexts and background, let us turn now to the essays themselves. I have used the edition of 1837, which was based on the second edition of the complete work, dating from 1816. However, it is worth noting that Owen made revisions and additions to subsequent English, French and American versions, so the reader will come across occasional references and allusions to developments which are out of context with the period when the essays were first written. I shall draw to yo
4.13.1 Standards and classification
ICTs depend on myriad standards in order to provide interconnectivity. If this was a computer science course, you would be learning about standard network protocols which enable computers to communicate with each other or with other devices, whether over the internet or from your computer to a network printer. Standards enable us to send email and browse websites without worrying about the underlying mechanisms (until they fail, forcing us to focus on the tool instead of our work).
1.3.1 Why are cells different?
Now let us go on with our story and assume that we have decided the time is right to have a baby. The primary requirement for conception is that healthy gametes should be produced. We shall therefore look first at how gametes are made, and then examine some of the factors affecting their quality. But we must start with an explanation of what gametes are, and what sets them apart from other kinds of cell. In other words, what makes gametes special? Gametes are the cells that fuse to form a new
Module team
The T822 course team
David Reed (Chair and author)
Jill Alger (Editor)
Chris Bissell (Critical reader and author)
Philippa Broadbent (Print buyer)
David Chapman (Author)
Daphne Cross (Assistant print buyer)
Glen Darby (Graphic designer)
Donna Deacon (Course secretary)
Alan Dolan (Course manager)
Roger Jones (Author)
Jo Lambert (Learning projects manager)
Roy Lawrance (Gra
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House Approves Sandy Aid, Senate Votes Next Victims of Hurricane Sandy are one step closer to getting a major infusion of federal disaster aid. Tuesday night, the House approved a $50 billion assistance package. This type of funding has typically been noncontroversial. But the Sandy aid has been a battle.
Superstorm Sandy: Before, During And Beyond
The Northeast region recovers from the massive storm which killed more than 100 people.
House Approves Sandy Aid, Senate Votes Next
House Approves Sandy Aid, Senate Votes Next 3:54
January 16, 20134:00 AM ET
Heard on Morning Edition
Tamara Keith
Victims of Hurricane Sandy are one step closer to getting a major infusion of federal disaster aid. Tuesday night, the House approved a $50 billion assistance package. This type of funding has typically been noncontroversial. But the Sandy aid has been a battle.
STEVE INSKEEP, HOST:
Yeah, it's Wednesday. It's MORNING EDITION from NPR News. I'm Steve Inskeep.
RENEE MONTAGNE, HOST:
And I'm Renee Montagne.
Victims of Hurricane Sandy are one step closer to getting a major infusion of federal disaster aid after a long delay. Last night, the House approved a $50 billion assistance package.
NPR congressional correspondent Tamara Keith reports.
TAMARA KEITH, BYLINE: Funding disaster relief is supposed to be one of the easier things Congress does. Not this time around. Late last year, the Senate approved a Sandy relief package, only to see it die in the House with the start of the new Congress. The criticism, especially from New York and New Jersey Republicans was fast and fierce. House speaker John Boehner quickly promised to revive the measure and he followed through yesterday.
New Jersey Republican Frank LoBiondo still seemed raw when he spoke in favor of the bill on the House floor.
REPRESENTATIVE FRANK LOBIONDO: I've asked my colleagues, because we seem to be very mixed and divided on some of this, think of a human face. My constituents, the constituents of the Northeast, they're not just whining. They're not just uncomfortable. They are devastated.
KEITH: New York Democrat Carolyn Maloney says it was never this hard with past disasters.
REPRESENTATIVE CAROLYN MALONEY: We were there with the aid. We didn't delay. We didn't put roadblocks. We didn't put forward all types of requirements to be met. We've voice-voted. We moved swiftly.
KEITH: But the Hurricane Sandy aid package happened to arrive at the House at a time of increased agitation over the deficit, at a time when spending has become a dirty word.
REPRESENTATIVE JEFF DUNCAN: We're $16 trillion in debt, America.
KEITH: South Carolina Republican Jeff Duncan reflects the way a whole lot of House Republicans felt about the $50 billion bill.
DUNCAN: We cannot keep spending money that we don't have on things that we can't afford; and all the while, sending our children and our grandchildren the bill. What part of $16 trillion in debt do ya'll not understand?
KEITH: Duncan was co-author of an amendment that would have required across the board spending cuts to offset the disaster aid funds. That amendment failed, but the majority of Republicans supported it.
And so, when it came to the final vote on the full bill
ERICA ELLIOTT: Total votes: 241 yay.
KEITH: This is Erica Elliott, an aide to the majority whip, reading the tally to reporters.
ELLIOTT: Forty-nine Republican yays, 179 nays.
KEITH: It passed because a whole lot of Democrats joined those few Republicans in voting aye. The governors of New York and New Jersey praised the House for pulling together a unified bipartisan coalition. But that's not normally how things happened in John Boehner's House.
Until very recently - just before the vote on the fiscal cliff deal - Boehner held to the idea that any bill coming up for a vote needed to have the support of the majority of his conference. The fiscal cliff bill didn't and neither did this one.
John Fleming, a Republican from Louisiana says the speaker had to bring it up for a vote - there was too much political pressure. And that informal rule about a majority of the majority, it may no longer be relevant, he says.
REPRESENTATIVE JOHN FLEMING: Since this is a Democrat president and a Democrat Senate, I don't think that really holds. I don't think that really matters. I think we should vote our conscious, vote the way we think we should, and try to influence the outcome as best we can. But we are, two-to-one, in the minority.
KEITH: So what does this mean for the next big fights, the debt ceiling and keeping the government funded? It's not clear yet. Boehner will find out what his caucus really thinks at a retreat in Virginia at the end of this week.
Tamara Keith, NPR News.
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House Approves $50.7B For Sandy Victims Jan. 15, 2013
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Disney's Pocahontas Animated Storybook Download (1995 Educational Game)
Educational Games:
Download full Disney's Pocahontas Animated Storybook:
Disney's Pocahontas Animated Storybook screenshots:
In addition to the narrated story of Pocahontas, players can choose to have the book read to them or play within the story. In straight narration, the story runs to the end of the page and then moves on to the next without pause. In the play the story variation, the program reads the page and then halts, leaving players free to explore.
The cursor becomes a white leaf. By moving the cursor around the screen, players can see where the leaf turns black. If they click on one of these areas, an animation is revealed. In addition, in two of the scenes: The English settlers village and the Powhatan village, are panoramic scenes that can be scrolled through by moving the mouse to the left or right and clicking on the arrowheads that appear in the middle of the screen.
In addition to the storybook aspects, there are four games you can play. These can either be accessed from Grandmother Willow's screen or by clicking the pictograph of children playing during the play through the story section.
Hoops and Arrows has players testing their archery skills before Koocoum. Players must shoot the hides stretched on the hoops with their arrows. The mouse changes the direction of the arrow. At higher difficulty levels, the hoops move. After all the hoops are shot, the game begins again.
In Spearing Berries, players play Flit. You must spear the berries before Meeko eats them all by flying over to the berries while they are in the air and clicking on them with the mouse. At higher difficulty levels, the height of the thrown berries varies, as does the speed with which they fall.
In Where's Meeko? Players must help Percy find Meeko, who has sneaked on board the settlers' ship. Players must click on various boxes, barrels, and crates to see where that wily raccoon will show up next. As soon as you have found him, he hides again. There are no levels to this game.
Finally, in Find the Animals, Chief Powhatan tells you to listen with your heart to find where the animals live. Players must click on an animal Petroglyph, then click on an area where they think the animal lives. If they are right, the animal appears and Chief Powhatan tells you what his tribe calls the animals and how to pronounce the Indian word or words for that animal.
At higher levels, the sparkles that guide you to where animals live are gone, and the animal sounds are more difficult to recognize.
Graphics: Excellent. Many of the scenes are taken from the movie.
Sound: Very good. Every sound comes through loud and clear.
Enjoyment: Extremely enjoyable. Any child who enjoyed the movie will enjoy this game.
Replay Value: The games are entertaining and educational at the same time. Players can challenge themselves over and over again.
Follow the story of Disney's Pocahontas through the Pocahontas Animated Storybook. Pocahontas, along with her friends Flit the hummingbird and Meeko the Raccoon help avert a war between the settler and the Native American Indians. Pocahontas befriends the explorer John Smith and teaches him the great love her people have for the land. But the settlers are afraid of the Indians, and soon, both sides have nearly come to blows Pocahontas' great courage in shielding John Smith from execution by her father Powhatan and then John Smith's throwing himself in front of the bullet meant for Powhatan, contrive to bring a sort of peace between the settlers and the Native Americans that lasts for many years. The story is narrated by Grandmother Willow and includes four games players can play, either as part of the story, or separately.
This game has been set up to work on modern Windows (10/8/7/Vista/XP 64/32-bit) computers without problems.
People who downloaded Disney's Pocahontas Animated Storybook have also downloaded:
Disney's Hercules Animated Story Book, Disney's Hunchback of Notre Dame Animated Storybook, Disney's The Lion King Animated Storybook, Disney's MathQuest with Aladdin, Disney's The Lion King Activity Center, Disney's Beauty and the Beast: Be Our Guest, Disney's Mickey Saves the Day: 3D Adventure, Disney's Animated Storybook: Toy Story
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Home » Horse Racing » Older Horses Show Off Newest Tricks in Deep Oaklawn Handicap Field
Older Horses Show Off Newest Tricks in Deep Oaklawn Handicap Field
By Brian Robin on May 2, 2020 3 min read
This is scheduling as brilliant as the race its talent promises. In between the split Arkansas Derby divisions on Oaklawn Park’s dynamic closing day card rests the $600,000 Grade 2 Oaklawn Handicap – a race punching far above its Grade 2 status.
Combatant pulled off a mild upset in winning March’s Santa Anita Handicap. The 5-year-old is a 4/1 favorite to win the Oaklawn Handicap. (Image: Benoit Photo for AP)
Put the grade aside. Far aside. This year’s Oaklawn Handicap could be a preview of November’s Breeders’ Cup Classic, such is the field depth for this 1 1/8-mile race. There are nine graded stakes winners and 13 stakes winners in the 13-horse field.
The Oaklawn Handicap is one of country’s premier races for older horses, so the deep field shouldn’t be surprising, even in the COVID-19 era. After all, this is a race with Snow Chief, Best Pal, Cigar, Medaglia d’Oro, and Will Take Charge on its winner’s list.
But this gives you an idea of how deep the Oaklawn Handicap talent pool is. Tacitus finished second in both the 2019 Belmont Stakes and Travers Stakes. He has hit the board in eight of his 10 races, won two Derby preps last year (Tampa Bay Derby and the Wood Memorial), and owns $2,677,500 in career earnings. He debuted as a 4-year-old with a fifth in January’s $20 million Saudi Cup, the world’s richest race.
And at 9/2, he’s not your Oaklawn Handicap favorite.
Back to His 3-Year-Old Home
That would be Combatant (4/1), who returns to a comfort zone of sorts. One of Oaklawn’s top 3-year-olds in 2018, Combatant finished second or third in three of the track’s four Derby prep races and fourth in the flagship Arkansas Derby. The Hronis brothers purchased him in late 2019 and turned him over to trainer John Sadler, who treated them to a Grade 1 Santa Anita Handicap victory in early March.
Post Positions (weight) and Morning Line (jockey)
Chess Chief (114), 30/1 (Brian Hernandez Jr.)
Trophy Chaser (115), 12/1 (Samy Camacho)
Bravazo (115), 30/1 (Miguel Mena)
Freeze (118), 6/1 (Joe Talamo)
Identifier (116), 20/1 (Stewart Elliott)
Warrior’s Charge (118), 8/1 (Florent Geroux)
Combatant (120), 4/1 (Joel Rosario)
Sky Promise (114), 20/1 (Orlando Mojica)
Tacitus (121), 9/2 (John Velazquez)
Captivating Moon (113), 20/1 (Julien Leparoux)
Tax (117), 15/1 (Kendrick Carmouche)
By My Standards (118), 9/2 (Gabriel Saez)
Night Ops (116), 15/1 (Javier Castellano)
“He put in a good third in the prep for the Big Cap, and then ran really well in the Big Cap,” Sadler told Oaklawn’s Jennifer Hoyt. “He’s a horse that is doing really well right now. He was a good horse when we got him. He was coming off a win at Churchill Downs. We got him out here (to California). My thought is there’s always room in the handicap division. He’s not disappointed us.”
Time Off Served By My Standards Well
Nor has By My Standards (9/2) disappointed his connections. Not after winning both his 2020 starts: a February allowance by six lengths and the Grade 2 New Orleans Classic by three in March. The 2019 Louisiana Derby winner took nine months off after finishing a disappointing 12th in the Kentucky Derby. He owns four victories, two seconds and a third in eight starts, along with nearly $922,000.
“He was very impressive off the layoff,” trainer Bret Calhoun said. “He didn’t run against top horses, but he came back against good horses and did the same thing, so it was very impressive … I think there’s more in the tank. I always thought all along that he could be one of the top older horses in the country this year.”
Mr. Freeze is in Sizzling Form
And we haven’t gotten to Mr. Freeze (6/1), who owns five wins and four seconds in 11 starts on dirt. This includes winning the Grade 2 Gulfstream Park Mile Stakes in February with a career-high 115 Equibase Speed Figure. Nor Warrior’s Charge (8/1), the home-track hero, who won three of five starts at Oaklawn and finished third in the other two. He opened his 4-year-old campaign by winning the Grade 3 Razorback Handicap in February.
Bob Baffert’s talented, troubled Improbable carried 8/1 odds before scratching Saturday morning.
Tags: By My Standards Combatant Horse Racing Improbable Oaklawn Handicap Oaklawn Park Tacitus
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