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The dataset generation failed

Error code:   DatasetGenerationError
Exception:    ArrowInvalid
Message:      JSON parse error: Missing a closing quotation mark in string. in row 146
Traceback:    Traceback (most recent call last):
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/packaged_modules/json/json.py", line 145, in _generate_tables
                  dataset = json.load(f)
                File "/usr/local/lib/python3.9/json/__init__.py", line 293, in load
                  return loads(fp.read(),
                File "/usr/local/lib/python3.9/json/__init__.py", line 346, in loads
                  return _default_decoder.decode(s)
                File "/usr/local/lib/python3.9/json/decoder.py", line 340, in decode
                  raise JSONDecodeError("Extra data", s, end)
              json.decoder.JSONDecodeError: Extra data: line 2 column 1 (char 1794)
              
              During handling of the above exception, another exception occurred:
              
              Traceback (most recent call last):
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1995, in _prepare_split_single
                  for _, table in generator:
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/packaged_modules/json/json.py", line 148, in _generate_tables
                  raise e
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/packaged_modules/json/json.py", line 122, in _generate_tables
                  pa_table = paj.read_json(
                File "pyarrow/_json.pyx", line 308, in pyarrow._json.read_json
                File "pyarrow/error.pxi", line 154, in pyarrow.lib.pyarrow_internal_check_status
                File "pyarrow/error.pxi", line 91, in pyarrow.lib.check_status
              pyarrow.lib.ArrowInvalid: JSON parse error: Missing a closing quotation mark in string. in row 146
              
              The above exception was the direct cause of the following exception:
              
              Traceback (most recent call last):
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1529, in compute_config_parquet_and_info_response
                  parquet_operations = convert_to_parquet(builder)
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1154, in convert_to_parquet
                  builder.download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1027, in download_and_prepare
                  self._download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1122, in _download_and_prepare
                  self._prepare_split(split_generator, **prepare_split_kwargs)
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1882, in _prepare_split
                  for job_id, done, content in self._prepare_split_single(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 2038, in _prepare_split_single
                  raise DatasetGenerationError("An error occurred while generating the dataset") from e
              datasets.exceptions.DatasetGenerationError: An error occurred while generating the dataset

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pred_label string	pred_label_prob float64	wiki_prob float64	text string	source string
__label__cc	0.685781	0.314219	Space Marine 2 Trailer In the 28 years since I started playing Warhammer it has been inevitable that there would be breaks as exams, employment and just general life got in the way of my escapism. There was always something that dragged me back - the stunning Eldar artwork for a new codex in 1998, the release of Lord of the Rings models a few years later and the amazing release of Space Marine on PS3 (heralding the end to the last break I had in the hobby). I loved the feel of Space Marine, it was like Gears of War but in a (subjectively) way cooler universe. The hordes of Orks and the challenge of Chaos marines created a beautiful dynamic which helped capture what it felt like to be a Space Marine. I spent many, many hours playing the multiplayer with my brother Drake (from Battle Bunnies and Titan Owners Club) and a couple of friends from work at the time who were gamers but not tabletop gamers. Needless to say they both play Warhammer now lol. So, naturally, last nights announcement has me positively giddy with the prospect of playing as Titus again and I can’t wait to see some more of the details. The small gameplay teaser suggests it is more of the same that we all loved from the first outing - except against hordes of ravening Tyranids. This is something I definitely want to be covering here and I can’t wait to get a few more details later today!! Here is a link to the official trailer: https://m.youtube.com/watch?v=TgxVQRTXtz0 And stay tuned to https://www.warhammer-community.com today as they are having another two Space Marine 2 articles go up throughout the day. Until next time, stay fluffy!	cc/2022-05/en_middle_0078.json.gz/line1
__label__cc	0.660132	0.339868	best about news angelsoutter Coles Supermarket Is Evacuated After The Floor Begins Caving In Your Blog » Coles Supermarket Is Evacuated After The Floor Begins Caving In Previous: Authorized Advice On How To Clean Your Tongue Correctly Next: Roma Agrawal Says Engineering Wants A lot more Females Seek guidance from All-natural England if you have bats living in your loft as they are a protected species. You will, however, need constructing regulations approval to make certain the loft is structurally sturdy enough and sound insulated, and there is safe escape from a fire. This could force you to take pricey fire-proofing measures throughout the property, such as enclosing any open-program staircase to the front door. University departments employ structural engineers as researchers and lecturers. You can make speculative applications using Uncover an Engineer to search for structural engineering practices. Following an investigation, EGM reprimanded Pratt and restricted him from practising structural engineering. Pratt is still permitted to practise as an engineer in other disciplines.Know the schools. Do you research on potential schools. Yearly, there is a list of rankings on the prime engineering schools. 8 Schools like MIT, University of California Berkeley, and Stanford are consistently ranked at the best of the list. 9 Study via their internet sites and turn out to be familiar with what courses they offer as well as their curriculum.D uring these years, he formulated his personal conception of purity of structure, and made a specific study of the operate of click through the following website page great Italian engineer Pier Luigi Nervi, scandalising the engineering establishment by announcing that Nervi's buildings were "mediocre architecture with jewels of structure inside them".Obtain an internship. Here's more info on click through the following website page look into our own web site. Internships give students with an opportunity to achieve genuine-world operate expertise. There are a selection of internship possibilities. You may select to intern at a pharmaceutical business, laboratory, or click through the following website Page engineering firm. If you are interested in pursuing an sophisticated degree, you may wish to conduct investigation with a professor.Get involved in extracurricular activities, also. Go to a math or science camp in the summer, for instance, or join the robotics club at your school. There are also regional, state, and nation-wide engineering competitions. four Do anything that will give you a wider foundation.If you are arranging on studying engineering at university, your Ucas application demands to be structurally sound. Most schools do not offer the topic, so reading up on it is all the much more crucial. Luckily, there's no shortage of material to stoke your enthusiasm.Production, works and upkeep managers strategy, organise and direct the activities and resources required for production in manufacturing industries and the maintenance of engineering equipment. Associated job titles: Engineering manager factory manager production manager service manager shift manager functions manager. Your working hours will usually be 9am to 5pm, Monday to Friday, with some occasional evening and weekend function exactly where necessary. Self-employment is feasible as the building of a structure requires projects that are put out to tender. Structural engineers that operate on a contract basis are recognized as contract engineers. Setting up your own consultancy is an alternative.Like a unit from a kids' cartoon, they are all functioning at the cutting edge of their field. Simon is searching at power - calling retired geologists to discover out the world's accurate oil reserves as official figures are just plain wrong. Tristan is attempting to model buildings on to an Xbox games console - so medical doctors and nurses can "stroll even though" new hospitals prior to they are built and point out design and click through the following website page style flaws. On the wall, click Through The following website page there is a project they are all contributing to: the Airport of the Future.Do a practicum in your final year of school. A practicum is a perform chance that replaces or requires up a significant portion of your final university year. These placements carry a competitive salary and give a deeper, more extended-term expertise than an internship. If you do well, practicums typically lead to complete-time positions following you graduate.Newby was born in Barnsley, Yorkshire. He went up to Cambridge to study engineering at Trinity College during the war, and was conscripted into national service afterwards. It was not until 1949 that he was able to look for a job in his field, at which time the most fascinating structural developments in architecture concerned the use of concrete shells, as at the celebrated Brynmawr Rubber factory in Wales, engineered by Ove Arup and Partners.I want to grow to be a civil engineer but men and women discourage me because I am a female. In most cases, actually require a certain education for this job. Some sound & image schools provide certificates for your introduction to this market. On the internet Nanodegrees in personal computer science, engineering, and machine finding out.Some men and women go into engineering to give themselves a strong technical background for specific kinds of law. Some individuals who study biology-related engineering select to grow to be physicians, dentists, or even vets. Biomedical engineering provides you a powerful background for going into these issues, if that is your option.	cc/2022-05/en_middle_0078.json.gz/line6
__label__wiki	0.939527	0.939527	How old is Rachel Shenton? Question: How old is Rachel Shenton? Is Rachel Shenton deaf? When did Mitzee leave Hollyoaks? Where does the silent child take place? Who wrote the silent child? Is Maisie sly deaf? Who is Rachel Shenton married to? Is mitzeee coming back to Hollyoaks? Who killed Riley Hollyoaks? Is Maisie Sly really deaf? Is silent child a true story? Are Maisie Slys parents deaf? Did Maisie sly win an Oscar? Is Rachel Shenton married? Who is the new guy in Hollyoaks? Is Diane from Hollyoaks pregnant? Is Mercedes pregnant in Hollyoaks? Is Silas Bobbys grandad? How old is Maisie sly? Is the silent child based on a true story? When Shenton was 12, her father became deaf after undergoing chemotherapy treatment for cancer. Following the death of her father, Shenton learned British Sign Language. In 2011, Shenton was made ambassador for the National Deaf Childrens Society and she continues to raise awareness of deafness in the UK. Rachel decided to quit the role of Mitzeee in October 2012. rural England Set in rural England and inspired by real life events. The Silent Child centres around a profoundly deaf four year old girl named Libby who is born into a middle class family and lives in a world of silence until a caring social worker teaches her the gift of communication. Rachel Shenton The Silent Child/Screenplay Maisie Sly, a profoundly deaf six-year-old from Swindon, has just played the lead role in an Oscar-winning film. Chris Overton (2018–) Rachel Shenton/Partner HOLLYOAKS Rachel Shenton has ruled out a return to the soap as Mitzeee Minniver for its 25th anniversary. The actress, 32, appeared on todays Lorraine to promote her latest show All Creatures Great And Small. Since leaving the soap in 2013 Rachel has gone on to win an Oscar for her short film The Silent Child. Simon Walker Riley leaves the house to find Mitzeee but, when he finds her, he is accidentally shot by Simon Walker (Neil Newbon). Riley is taken to hospital but later dies, with Mitzeee by his side. Maisie Sly, a profoundly deaf six-year-old from Swindon, has just played the lead role in an Oscar-winning film. “There arent many six-year-olds who can say that,” smiles her father Gilson from the familys Airbnb in Glendale, a residential area of Los Angeles. The Silent Child, a short film based on a true story about a deaf child, won an Oscar on Sunday night. Her powerful speech she made clear that the film is based on the lives of many deaf children around the world today who do not have proper access to language or education. Meet Maisie Sly, the profoundly deaf girl from Swindon who brought sign language to the Oscars. Maisie stars in the film as Libby, a four-year-old deaf girl born into a hearing family, who has suffered from living in silence through her early life, after going undiagnosed for three and a half years. Meeting the Sly family for the first time is an extraordinary experience. Parents Gilson and Elizabeth and their three small children are all deaf and communicate with each other entirely through sign language. Maisie Sly, whos six, is the star of The Silent Girl which won an Oscar for Best Live Action Short. The Silent Child is about a deaf girl called Libby, played by Maisie, who lives in silence until a social worker teaches her how to communicate through sign language. Fergus Collins (Robert Beck) - joined Brookside legend Robert Beck joined Hollyoaks back in March 2021. The actor - who is married to Coronation Street star Jane Danson - plays Fergus Collins, Brad Kings former business associate and Trish Minnivers ex-boyfriend. Were sending love and congratulations this week to Hollyoaks actress Alex Fletcher, who has revealed that she is expecting her second child with husband Neil Davies. The 39-year-old, who plays Diane OConnor in the show, told Hello! magazine that she is set to welcome a son in three month. Hollyoaks is set to air an incredibly dark baby kidnap storyline in scenes to come, as Mercedes McQueen finds out the heartbreaking news she is not pregnant, when she attends her first scan. Bobby develops a strong father-son relationship with Sylver McQueen after he starts dating Mercedes, with Sylver and Mercedes marrying in 2019. In January 2021, when his family is being blackmailed, Bobby is taken from the airport by his serial killer grandfather, Silas Blissett, Who is out to get Mercedes. 10 years (2011) Maisie Sly/Age Set in rural England and Inspired by real life events. The Silent Child film centres around a profoundly deaf four year old girl named Libby who is born into a middle class family and lives in a world of silence until a caring social worker teaches her the gift of communication.	cc/2022-05/en_middle_0078.json.gz/line7
__label__wiki	0.63059	0.63059	This page was originally published on Monday 22 March, 2004. Tuesday 23 March, 2004 >> WorldNews Media Kit - The World News Network Entertainment Sports Editorial Broadcasts Photos WN Links Submit Photo Sitemap Feedback MediaConference News Review WorldNews Network Media Kit Mon Mar 10 14:40:03 2003 Media Kit Index About World News Network The New Generation Advertising Medium Advertising on WN Size and Specifications Contact our Advertising Team About WorldNews Network WorldNews.com: TOP Website for Global News coverage. ---Brittannica.com Wn.com: Favourite information site for current events. ---US News ---World Report The WorldNews (WN) Network was founded in 1998 with the primary objective of being the most comprehensive, one-stop news resource on the Internet. Today, WN has over 1500 thematic and regional news sites. It also includes the web's most comprehensive news search engine. A global leader in online news, WN utilises more than 300 sources, from The Times of India to the Washington Post, delivering unparalleled coverage on a vast range of subjects. Testament to the popularity is WN's viewership growth rate. From 30 million in 2000, WN has touched a staggering 90 million in 2002. What makes WN so popular... Global news from varied sources, different perspectives, in 20 languages Unique, proprietary, comprehensive and multilingual Search Engine Remarkable ease of navigation Completely free and available to all "No editorial - No bias" principle allows readers to form their own picture of reality and make their own judgements Contents of interest to a wide range from school children to business professionals Here's what specialists have to say about WN... It's an amazing collection of specialized knowledge. ---Forbes. 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Top \| Languages \| Jobs \| Submit Photos \| WN Links \| WN Network \| ©2003 World News Network Contact our Advertising team for Advertising and Sponsorship on WorldNews.com and the WorldNews Network	cc/2022-05/en_middle_0078.json.gz/line8
__label__wiki	0.503008	0.503008	22 Kansas City Chiefs at Las Vegas Raiders • Thursday Nov. Diego Chara 14. • MLB said that Hall of Fame broadcaster Vin Scully has narrated the official World Series documentary, The 2020 World Series, , which chronicles the first Dodgers championship since 1988. The 2020 World Series 90-minute DVD and digital versions will be available Dec. NYSJ: Cars 2 TVH: We look for ways to get involved with entertainment and music that we see can be good places to build on our messages. Ralph Lauren is also an officlal partnerwith the U.S. Lucas Zelarayan 24. PRBar’s line of Team USA performance nutrition bars, as well as PRBar’s U.S. 10, Reebok will donate one pair of JJ III’s, up to $90 in retail value, to the Mission of Yahweh in Houston, an organization for women and children that offers shelter and programs focused on ending homelessness and dependency. Gonzalo Higuain custom football jerseys Cristiano Ronaldo $105 million $60 million $45 million Soccer 3. Open and WImbledon. Minnesota Vikings 20. 6 Denver Broncos at Kansas City Chiefs • Dec. The collection includes 1 oz. But, of course, it can be carried into other leagues. 13 Pittsburgh Steelers at Buffalo Bills • Dec. Pitchers Barry Zito, Tim Hudson, Mark Buehrle and A.J. Javier Hernandez 3. According to Topps, the set was a precursor to the ones we know today, with 52 cards in separate sets, or decks, which were designed to https://www.amazon.com/dp/B0837PBH81 kids play a game of card-baseball. 5 • Super custom jerseys LVIII Mercedes-Benz Superdome New Orleans Feb.	cc/2022-05/en_middle_0078.json.gz/line10
__label__wiki	0.783491	0.783491	Fauci As Darth Vader Of The Covid wars By Pepe Escobar Nov 26, 2021 - 9:35:06 PM https://asiatimes.com/2021/11/fauci-as-darth-vader-of-the-covid-wars/ Dr Anthony Fauci. Photo: Olivier Douliery / AFP / Getty Robert F Kennedy Jr's The Real Anthony Fauci: Bill Gates, Big Pharma and the Global War on Democracy and Public Health should be front-page news in all the news media in the US. Instead, it has been met with the proverbial thundering silence. Critics seeking to have Kennedy dismissed as a kook trading on a famous name had scored a hit in February, when Instagram permanently deleted his account, allegedly for making false claims about coronavirus and vaccines. Nevertheless, the book, published only a few days ago, is already a certified pop hit on Amazon. RFK Jr, chairman of the board of and chief legal counsel for Children's Health Defense, sets out to deconstruct a New Normal, encroaching upon all of us since early 2020. In my early 2021 book Raging Twenties I have termed this force techno-feudalism. Kennedy describes it as "rising totalitarianism," complete with "mass propaganda and censorship, the orchestrated promotion of terror, the manipulation of science, the suppression of debate, the vilification of dissent and use of force to prevent protest." Focusing on Dr Anthony Fauci as the fulcrum of the biggest story of the 21st century allows RFK Jr to paint a complex canvas of planned militarization and, especially, monetization of medicine, a toxic process managed by Big Pharma, Big Tech and the military/intel complex - and dutifully promoted by mainstream media. By now everyone knows that the big winners have been Big Finance, Big Pharma, Big Tech and Big Data, with a special niche for Silicon Valley behemoths. Why Fauci? RFK Jr argues that for five decades, he has been essentially a Big Pharma agent, nurturing "a complex web of financial entanglements among pharmaceutical companies and the National Institute of Allergy and Infectious Diseases (NIAID) and its employees that have transformed NIAID into a seamless subsidiary of the pharmaceutical industry. Fauci unabashedly promotes his sweetheart relationship with Pharma as a ‘public-private partnership.'" Arguably the full contours of this very convoluted story have never before been examined along these lines, extensively documented and with a wealth of links. Fauci may not be a household name outside of the US and especially across the Global South. And yet it's this global audience that should be particularly interested in his story. RFK Jr accuses Fauci of having pursued nefarious strategies since the onset of Covid-19 - from falsifying science to suppressing and sabotaging competitive products that bring lower profit margins. Kennedy's verdict is stark: "Tony Fauci does not do public health; he is a businessman, who has used his office to enrich his pharmaceutical partners and expand the reach of influence that has made him the most powerful - and despotic - doctor in human history." This is a very serious accusation. It's up to readers to examine the facts of the case and decide whether Fauci is some kind of medical Dr Strangelove. No Vitamin D? Pride of place goes to the Fauci-privileged modeling that overestimated Covid deaths by 525%, cooked up by fabricator Neil Ferguson of the Imperial College in London and duly funded by the Bill and Melinda Gates Foundation. This is the model, later debunked, that justified lockdown hysteria all across the planet. Kennedy attributes to Canadian vaccine researcher Dr Jessica Rose the charge that Fauci was at the frontline of erasing the notion of natural immunity even as throughout 2020 the CDC and the World Health Organization (WHO) admitted that people with healthy immune systems bear minimal risk of dying from Covid. Dr Pierre Kory, president of Front Line Covid-19 Critical Care Alliance, was among those who denounced Fauci's modus operandi of privileging the development of tech vaccines while allowing no space for repurposed medications effective against Covid: "It is absolutely shocking that he recommended no outpatient care, not even Vitamin D." Clinical cardiologist Peter McCullough and his team of frontline doctors tested prophylactic protocols using, for instance, ivermectin - "we had terrific data from medical teams in Bangladesh" - and added other medications such as azithromycin, zinc, Vitamin D and IV Vitamin C. And all this while across Asia there was widespread use of saline nasal lavages. By July 1, 2020, McCullough and his team submitted their first, ground-breaking protocol to the American Journal of Medicine, which was widely downloaded. McCullough complained last year that Fauci had never, to date, published anything on how to treat a Covid patient. He additionally alleged without corroborating evidence: "Anyone who tries to publish a new treatment protocol will find themselves airtight blocked by the journals that are all under Fauci's control." It got much worse. McCullough: "The whole medical establishment was trying to shut down early treatment and silence all the doctors who talked about success. A whole generation of doctors just stopped practicing medicine." (A contrarian view would argue that McCullough got carried away: A million US doctors - the approximate number practicing at any given time - could not all have been in on it.) The book argues that the reasons there was a lack of original research on how to fight Covid were the dependence of much-vaunted American academics on the billions of dollars granted by the National Institute of Health (NIH) and the fact they were terrified of contradicting Fauci. Frontline Covid specialists Kory and McCullough are quoted as charging that Fauci's suppression of early treatment and off-patent medication was responsible for up to 80% of deaths attributed to Covid in the US. How to kill the competition The book offers a detailed outline of an alleged offensive by Big Pharma to kill hydroxychloroquine (HCQ) - with research mercenaries funded by the Gates-Fauci axis allegedly misinterpreting and misreporting negative results by employing faulty protocols. Kennedy says that Bill Gates by 2020 virtually controlled the whole WHO apparatus, as the largest funder after the US government (before Trump pulled the US out of the WHO) and used the agency to fully discredit HCQ - a sweeping if not incendiary claim. The book also addresses Lancetgate - when the world's top two scientific journals, The Lancet and the New England Journal of Medicine - published fraudulent studies from a nonexistent database owned by a previously unknown company. Only a few weeks later both journals - deeply embarrassed and with their hard-earned credibility challenged - withdrew the studies. There was never any explanation as to why they got involved in what could be interpreted as one of the most serious frauds in the history of scientific publishing. But it all served a purpose. For Big Pharma, says Kennedy, killing HCQ and, later, Ivermectin (IVM) were top priorities. Ivermectin happens to be a low-profit competitor to a Merck product, molnupiravir, which is essentially a copycat but capable of being retailed at a profitable $700 per course. The book alleges Fauci was quite excited by a promising study of Gilead's remdesivir - which not only is widely seen as ineffective against Covid but is a de facto deadly poison, at $3,000 for each treatment. The book also suggests that Fauci might have wanted to kill HCQ and IVM because, under US federal rules, the Food and Drug Administration's recognition of both HCQ and IVM would automatically kill remdesivir. The Bill and Melinda Gates Foundation happens to have a large equity stake in Gilead. A key point for Kennedy is that vaccines were Big Pharma's Holy Grail. Robert F Kennedy Jr. Photo: NDTV.com He details how what could be construed as a Fauci-Gates alliance put "billions of taxpayer and tax-deducted dollars into developing" an mRNA "platform for vaccines that, in theory, would allow them to quickly produce new ‘boosters' to combat each ‘escape variant.'" Vaccines, he writes, "are one of the rare commercial products that multiply profits by failing ... The good news for pharma was that all of humanity would be permanently dependent on biannual or even triannual booster shots." Any similarities with our current "booster" reality are not mere coincidence. The final summary of Pfizer's clinical trial data will raise countless eyebrows. Peter McCullough: "Because the clinical trial showed that vaccines reduce absolute risk less than 1%, those vaccines can't possibly influence epidemic curves. It's mathematically impossible." The Gates matrix Bill Gates describes the operational philosophy of his foundation as "philantrocapitalism." It's more like strategic self-philantropy, as both the foundation's capital and his net worth have been ballooning. The Bill and Melinda Gates Foundation - "a nonprofit, fighting poverty, disease and inequity around the world" - invests in multinational pharma, food, agriculture, energy, telecom and global tech companies. It exercises considerable de facto control over international health and agricultural agencies as well as mainstream media - as the Columbia Journalism Review showed in August 2020. Gates, without a graduate degree, not to mention medical school degree (like author Kennedy, it must be noted, whose training was as a lawyer), dispenses wisdom around the world as a health expert. The foundation holds corporate stocks and bonds in Pfizer, Merck, GSK, Novartis and Sanofi, among other giants, and substantial positions in Gilead, AstraZeneca and Moderna. The book delves in minute detail into how Gates controls the WHO (the largest direct donor: $604.2 million in 2018-2019, the latest available numbers). Already in 2011 Gates suggested: "All 183 member states, you must make vaccines a central focus of your health systems." The next year, the World Health Assembly, which sets the WHO agenda, adopted a Global Vaccine Plan designed by - who else? - the Bill and Melinda Gates Foundation. The Foundation also reputedly controls the Strategic Advisory Group of Experts (SAGE), the top advisory group to the WHO on vaccines, as well as the crucial GAVI Alliance (formerly the Global Alliance for Vaccines and Immunization), which is the second-largest donor to the WHO. GAVI is a Gates "public-private partnership" that essentially corrals bulk sales of vaccines from Big Pharma to poor nations. British Prime Minister Boris Johnson, only three months ago, proclaimed that "GAVI is the new NATO." Few in East and West know that it was Gates who in 2017 handpicked the WHO's director general Tedros Adhanom Ghebreyesus - who brought no medical degree and a quite dodgy background. Dr Vandana Shiva, among India's leading human rights activists (routinely accused of being merely anti-vax), sums up: "Gates has hijacked the WHO and transformed it into an instrument of personal power that he wields for the cynical purpose of increasing pharmaceutical profits. He has single-handedly destroyed the infrastructure of public health globally. He has privatized our health systems and our food systems to serve his own purposes." Gaming pandemics The book's Chapter 12, "Germ Games," may arguably be its most explosive, as it focuses on the US bioweapons and biosecurity apparatus, with a special mention of Robert Kadlec, who might claim leadership of the - contagious - logic according to which infectious disease poses a national security threat to the US, thus requiring a militarized response. The book argues that Kadlec, closely linked to spy agencies, Big Pharma, the Pentagon and assorted military contractors, is also linked to Fauci investments in "gain of function" experiments capable of engineering pandemic superbugs. Fauci strongly denies he's promoted such experiments. In 1998 Kadlec had written an internal strategy paper for the Pentagon - though not for Fauci - promoting the role of pandemic pathogens as stealth weapons leaving no fingerprints. Since 2005 DARPA, which invented the internet by building the ARPANET in 1969, has funded biological weapons research. DARPA - call it the Pentagon's angel investor - also developed the GPS, stealth bombers, weather satellites, pilotless drones - and that prodigy of combat, the M16 rifle. In 2017 DARPA funneled $6.5 million through Peter Daszak's EcoHealth Alliance to fund "gain of function" work at the Wuhan lab, on top of gain of function experiments at Fort DetrickEcoHealth Alliance was the organization through which the financing went. RFK Jr dutifully connects the Germ Games progress, starting with Dark Winter in 2001, which emphasized the Pentagon's drive towards bioweapon vaccines (the code name was coined by Kadlec); the anthrax attack three weeks after 9/11; Atlantic Storm in 2003 and 2005, focused on the response to a terrorist attack unleashing smallpox; Global Mercury 2003; and Lockstep in 2010, which developed a scenario funded by the Rockefeller Foundation where we find this pearl: During the pandemic, national leaders around the world flexed their authority and imposed airtight rules and restrictions, from the mandatory wearing of face masks to body-temperature checks at the entries to communal spaces like train stations and supermarkets. Even after the pandemic faded, this more authoritarian control and oversight of citizens and their activities stuck and even intensified. In order to protect themselves from the spread of increasingly global problems - from pandemics and transnational terrorism to environmental crises and rising poverty - leaders around the world took a firmer grip on power. RFK Jr paints a picture in which, by mid-2017, the Rockefeller Foundation and US intel agencies had all but crowned Bill Gates as the top financier for the intel/military pandemic simulation business. Enter the MARS (Mountain Associated Respiratory Virus) simulation during the G20 in Germany in 2017. MARS happened to hit China. MARS was about a novel respiratory virus that spread out of busy markets in a mountainous border of an unnamed nation that looked very much like China. It gets curiouser and curiouser when one learns that MARS's two moderators were very close to the Bill and Melinda Gates Foundation. One of them, David Heymann, sat with the Moderna CEO on the Merieux Foundation USA Board. BioMerieux happens to be the French company that built the Wuhan lab. Big Pharma kisses Western intel Afterward came SPARS 2017 at the Johns Hopkins Center for Health Security. The Bill and Melinda Gates Foundation happen to be major funders of the Johns Hopkins Bloomberg School of Public Health. SPARS 2017 gamed a coronavirus pandemic running from 2025 to 2028. As RFK Jr. notes, "the exercise turned out to be an eerily precise predictor of the Covid-19 pandemic." In 2015, Microsoft founder Bill Gates warned about global pandemics in a TED Talk. Credit: File photo. By 2018, bioweapons expert Peter Daszak was enthroned as the key connector through whom grants were moved to fund gain-of-function research, including at the Wuhan Institute of Virology Biosafety Lab. Crimson Contagion, overseen by Kadlec after eight months of planning, came in August 2019. Fauci was on board the self-described "functional exercise," representing the NIH, alongside the CDC's Robert Redfield and several members of the National Security Council. The war game was supposedly held in secret, nationwide. In the After-Action Crimson Contagion Report, which only came out via a FOIA request, however, the list of participating organizations goes on and on for pages, including Indian tribes and county governments. It is impossible to determine from his organization's simple involvement that this was a Fauci project. The star of the Gates pandemic show was undoubtedly Event 201 in October 2019, held only 3 weeks before US intel may - or may not - have suspected that Covid-19 was circulating in Wuhan. Event 201 was about a global coronavirus pandemic. RFK Jr persuasively argues that Event 201 was as close as possible to a "real-time" simulation. The book's "Germ Games" chapter leads the reader to acknowledge what mainstream media have simply refused to report: how the pervasive involvement of US (and UK) intel has a secretive - yet dominating - presence in the whole response to Covid-19. A very good example is the Wellcome Trust - the UK version of the Bill and Melinda Gates Foundation - which is a spinoff of Big Pharma's GlaxoSmith Kline. This epitomizes the marriage between Big Pharma and Western intel. The Wellcome Trust chair, from 2015 to 2020, used to be a former director-general of MI5, Dame Eliza Manningham-Buller. She was also chair of the Imperial College, since 2001. The "English Dr Fauci," Neil Ferguson, of the infamous, deadly wrong models that led to all lockdowns, was an epidemiologist working for the Wellcome Trust. These are only a few of the insights, connections and loaded allegations woven through RFK Jr's book. As a matter of public service, the whole lot should be available for popular scrutiny worldwide (and indeed, the digital Kindle edition is priced at a rock-bottom $2.99). These matters concern the whole planet, especially the Global South. Nobel laureate Luc Montaigner has noted how, "tragically for humanity, there are many, many untruths emanating from Fauci and his minions." Even more tragic is what emanates from his masters.	cc/2022-05/en_middle_0078.json.gz/line16
__label__cc	0.665388	0.334612	businessmarketingservicecompany Online Gambling Tips, Trick And Strategy Home Gambling News Showing: 1 - 50 of 135 RESULTS Some Important Poker Tips To Make Cash Out Of It One of the best methods to earn large pots in buy in or totally free poker on-line video games is to know when and how much to bet. Simpler said than carried out of course and 1 of the biggest mistakes I see in relation to this lofty objective is over-betting. Right here are the … Colorado Sports Betting Enjoys Profitable First Month As summer draws nearer, major sports are putting into place plans to return to action. The NBA is ready to resume play July 31 in Orlando, Florida. While still needing final approval for it, the NHL appears to have the intention to get players back on the ice around the same time. Golf is back, while NASCAR and UFC are well … From Gaming Tables To Masks, Recapping Las Vegas’ Big Reopening Weekend As the clock struck midnight on June 4, you could almost feel the electric anticipation of people getting ready to finally visit Las Vegas casinos again. Casinos on the Vegas Strip opened at 8 a.m. and later on June 4. After a quick temperature check at many casinos, gamblers rushed in to place their first … Is Horse Racing The ‘Original Sports Bet’ With Long-Term Appeal For Gamblers? Alex Waldrop is as optimistic about the current and near-future state of the pari-mutuel industry as a president of the National Thoroughbred Racing Association could be after the Triple Crown has been postponed, reshuffled, altered. But with the Kentucky Derby moved from the first Saturday in May until Sept. 5, the traditional Triple Crown-capping Belmont … DraftKings Sportsbook Lands Partner For Michigan Sports Betting A major player in the world of legal sports betting has found an entrypoint into Michigan. DraftKings Sportsbook announced it has partnered with Bay Mills Indian Community, a tribe in the Upper Peninsula that operates two casinos in the state. As a result, ahead of Michigan launching online sports betting, DraftKings gains an avenue to its eighth state … When Will The NBA Return? Here’s The Latest Proposed Schedule The sports world came to a screeching halt three months ago. As the coronavirus pandemic rapidly spread, a prominent player in the NBA tested positive for COVID-19. After that player, Rudy Gobert, tested positive on March 11, the game between his Utah Jazz and Oklahoma City Thunder was postponed. Before the day ended, the NBA scrapped the remainder of the scheduled … In Post-Shutdown US, Will A Bigger Value Be Placed On Legal Online Gambling? In May 2018, the US Supreme Court repealed the Professional and Amateur Sports Protection Act, opening the door for state-sanctioned legal sports betting. That was just two years ago, but doesn’t it feel like much longer? It feels as if legalized wagering (outside Nevada) has existed as long as the traditional casino. There’s no doubt that … When Will NHL Return? There’s A New Plan In Place The Chicago Blackhawks are returning to the playoffs! Well, them and 24 other teams when the National Hockey League (NHL) resumes play. Much like other major sports leagues, the NHL has been on hiatus since March but a return is possible by late July. Commissioner Gary Bettman recently announced the ‘Return To Play Plan’ which … Las Vegas Casinos Prepare For June 4 Reopenings After what seems like months of quarantining, states across the country have started allowing businesses to reopen. Closed since mid-March due to the coronavirus pandemic, casinos have begun resuming operations. Normalization is well underway. But that does not mean we can stop being safe and smart. If anything, we need to emphasize it more. On … When Are Major Horse Racing Events Scheduled To Return? If it’s not already trademarked, Alex Waldrop should consider it. “We were the original sports bet. We’re still here. And we’re still going strong.” And with COVID-19 keeping sports contested by humans off their fields of play, the chief executive officer of the National Thoroughbred Racing Association earnestly hopes one of the United States’ original … Will Louisiana Sports Betting Hit The Ballot This Fall? What a magical day May 24 became. Four of the greatest athletes in their respective sports took to the links at Medalist Golf Club in Florida, pitting Tiger Woods and Peyton Manning against Phil Mickelson and Tom Brady. Through a downpour, these GOATs persevered. Not just for bragging rights (which went to Tiger and Peyton). Not only for our own entertainment (with cart cams and … Odds & How To Watch ‘The Match’ Golf — and betting on golf — is back, thanks to Tiger Woods and Phil Mickelson. Golf and gambling have gone together like golf and the nineteenth hole since duffers first pulled wood clubs from “bags” made of twine. The pace and segmentation of play, granular to the shot and the hole allows for the … How Can US Sports Return? Analyzing How To Get Back In The Safe Zone The job was always going to require immunologists. Developing a plan to safely relaunch college and professional sports is requiring foot doctors, too. Or at least one. Dr. Glenn Copeland is walking the immunologists, players and coaches toward what sports may look like during a post-COVID-19 pandemic. It will not be a quick fix, Copeland told PlayUSA, … Want To Bet On MLB? July Return Could Be A Possibility At this very moment, if anyone says they know definitively when Major League Baseball is returning, take it with a grain of salt. The truth is, while there have been many dates floating around all of it remains speculation. What is certain, and what we do know, is there are plans floating around to bring … The PGA Tour Returns – Get The Revised Tournament Schedule The first round of the Players Championship, the flagship tournament of the PGA Tour, came to a close March 12. By that point, the coronavirus pandemic was growing. Tour higher-ups were adamant about continuing the event, though without spectators. Hours later, though, there was a change of heart. The championship was scrapped. And since that … Casinos Beginning To Reopen Amid Coronavirus Pandemic It appears the light at the end of the tunnel is nearing. Following weeks of social isolation and distancing, closed businesses and schools, shuttered casinos and sportsbooks, normalization has begun. A number of states across the country have authorized select businesses to resume operations. For some, that includes the reopening of brick-and-mortar casinos, which, for … Las Vegas Casinos Detail Reopening Dates And Safety Plans Las Vegas casinos and non-essential businesses were ordered to close in March to help slow the spread of coronavirus. We can’t say with 100% certainty when Las Vegas casinos will reopen but we have an idea of dates and how they’ll approach opening for guests once again. The largest casino operators in Las Vegas recently … Las Vegas’ Innovative Drive-thru Sportsbooks Let Bettors Sign Up And Deposit Las Vegas drive-throughs have long been embodied by a burger the East Coasters lust over or weddings for lusty couples. Now they’re a means for Nevada sportsbooks like Circa Sports, South Point and William Hill to infuse business into retail shops darkened by casino shutdowns forced by the COVID-19 pandemic and hindered by archaic regulations. … A Look Back On How US Sports Betting Became Legal, Two Years Later Editor’s note: The federal ban on sports betting in the United States was struck down on May 14, 2018. This is a look back at how that day arrived in the US from a member of the sports betting industry. Over the lifetime of the American republic, the Supreme Court of the United States, the … When Gambling Hot Spots Reopen Casinos, How Will Things Look Different? It’s been a hellish two months for the land-based gaming industry following wide-spread casino closures due to the coronavirus pandemic. Though online casinos seem to be picking up some of the slack, people are out of work, state and local economies are holding on by their fingertips, and people are left wondering when and if … Horse Racing Bets Supplementing Minimal Sports Betting Options Welcome to another week of quarantine. Potentially, though, it won’t last much longer. States across the country have started reopening select businesses and easing isolation restrictions as they pertain to the coronavirus pandemic. They have developed policies and guidelines for the public and industries to follow in order to resume operations. In due time, it appears, … Handle19 Sportsbook Moving Forward With 2020 DC Sports Betting Plans The Coronavirus pandemic has affected the gambling industry across the world in many ways. Handle 19 sportsbook, which aims to be the first Class B operator for Washington, DC sports betting, is undeterred. In the current COVID-19 world, their goal remains unchanged. Handle19 still plans to open a brick-and-mortar location in the District later this … Big NASCAR Betting Anticipated As Races Return May 17 NASCAR is set to become one of the first major sports to return after a two-month hiatus due to the coronavirus pandemic. Action is set to begin on May 17, with three races at Darlington Raceway followed by two weeks of scheduled events. As with the return of any major sports, the main goal is … UFC Events In May Could Be The Injection Sports Betting Needs Right Now Dana White doesn’t get his Fight Island. At least not yet. So for now, the empty arena a few blocks from the St. John’s River will suffice for the impresario of the Ultimate Fighting Championship. And for sports bettors eager for something else familiar. The UFC’s bout is scheduled for Saturday, May 19 at Vystar … Solid Numbers, Easy Launch Helps Set Groundwork for Future By noon on Friday, Dan Hartman sensed reality settling in. Legalized sports betting in Colorado was two hours old. Four operators had live online sportsbooks. By that time, he recalled with a laugh, Hartman felt relief. The much-anticipated launch had occurred. What’s more, it went as smoothly as regulators, operators and the public could have wanted. That … Could The Impact Of COVID-19 On The Gaming Industry Spell Wire Act’s Demise? Fifty-nine years after the Wire Act was passed and 16 months after a Department of Justice re-interpretation of it sent a spasm through the burgeoning US gaming industry, stakeholders and entrepreneurs continue to debate over the extent to which the 20th-century law will impact their high-tech business opportunity. Such was the case at the SBC … PA, NJ See Uptick In Online Poker Championship Entries While we’re not out of the woods yet, states across the country are beginning to ease restrictions surrounding the coronavirus pandemic. Some will soon allow select businesses to reopen, of course with capacity limitations and social distancing guidelines in place. Online poker and online casinos have thrived during the shutdown, but major sports remain sidelined and … With Closed Casinos, Nevada’s March Gaming Revenue Suffered Major Drop Last week the Nevada Gaming Control Board reported that the amount of money won by Nevada casinos in March fell by almost 40% compared to the same period last year. Gaming revenue for the state was $618 million in March. That’s a decrease of 39.57% from March of 2019 when casinos won $1.022 billion. The … Colorado Sports Betting Officially Launches; DraftKings Offers Broncos Promo Colorado has become the 18th state with legal sports betting, going live today, May 1. Though the state’s physical casinos — located in rural Cripple Creek, Black Hawk, and Central City — are closed until May 8 due to recent extended shutdown, bettors can take advantage of the state’s online sports betting and place their bets. … Virginia Sports Betting Is Officially Legal After Delays Legalized Virginia sports betting is ready to colonize. Lawmakers enacted into law a pair of bills, HB 896 and SB 384, that take effect July 1, thus legalizing regulated wagering in Old Dominion. This comes after both the state House and Senate approved the bill in early March and then had the proposal sent back by Gov. Ralph Northam … Why Colorado Could Be A Major Player When Online Betting Begins For the past two years, legalized sports betting has permeated the country. State-regulated industries have cropped up in bunches along the east coast and in the heart of the Midwest. Forgotten, it seems, is the West. The American frontier. But soon, a gateway will open to what is otherwise an untapped region. The western United … US Sports Betting Industry Will Recover The future of the American sports betting industry remains promising, perhaps even record-setting next year, said gaming industry analyst and SpringOwl Asset Management CEO Jason Ader. This year, though, amid a COVID-19 pandemic that has shut down sports with cascading detriment to sportsbooks and sports networks, is about mitigating damage and learning lessons on how … Storm the Court, Nadal, Charlatan Aim for Derby Position in Arkansas The first Saturday in May should have brought the 146th running of the Kentucky Derby. Then COVID-19 intervened. Instead, May 2 will bring an important Derby prep race, albeit four months before the Run for the Roses’ new date on Sept. 5. And it will bring a wrinkle. Oaklawn Park officials will split the 1 … DraftKings Acquires SBTech And Finally Goes Public Another week of social distancing and quarantining is in the books. Another week closer, hopefully, to the light at the end of the tunnel. We hope everyone is staying safe, smart and sane in these trying times. It used to be that sports provide an outlet from reality. Alas, they remain sidelined. Even casinos could … Tennessee Sports Betting Could Arrive In July, But Here Are Some Critical Facts A skilled journalist once wrote, “I think there is a terrible angst on the land, a sense that something ugly is about to happen, an hour-to-hour feeling of nervous anticipation.” That was a bit of correspondence from Hunter S. Thompson to a friend in 1965. Though he was referring to Richard Nixon and not the … Global Poker Home Series Awarding Largest Online Poker Prize Pool The largest purse in the history of Global Poker awaits this weekend. On April 26, the sweepstakes-based online poker site wraps up its Global Poker Home Series with the biggest guarantee it has ever offered: a prize pool of SC500,000 during the SC540 Sunday Scrimmage. Not a bad payday during a time of quarantine. What … New Jersey, Pennsylvania Online Gambling Revenue See Big Uptick In March This was supposed to be a landmark time of the year. Two of the biggest and flourishing legal sports betting industries were supposed to be reaping the rewards of one of the sporting year’s busiest times: March Madness, MLB, the Masters, and postseason pushes for the NBA and NHL. What an incredible month — certainly one that would produce … So, What Sports Can You Bet On Legally During The Shutdown? My dog, a 1-year-old French bulldog named Gunther, has been meticulously judging me, wondering why I spend so much time looking for sports betting options when the industry is on hold. That’s because despite the pause of NBA and NHL seasons, the postponement of the start of MLB, and the uncertain start of NFL season, … WSOP Officially Postponed Due To Pandemic, But May Return This Fall The 51st running World Series Of Poker (WSOP) in Las Vegas has been postponed. The move comes after weeks of rumors and speculation that the largest poker tournament of the year will be delayed or canceled. Caesars Entertainment, operators of WSOP, says the postponement of the tournament is due to the public health emergency involving … TN, VA Sports Betting Slowly Moving Toward Launch It remains incredible that each week, despite the lack of sports, we still find ample news surrounding legalized sports betting. Casinos are still shuttered. Major sports are on hiatus. Understandably, sports betting handles and revenues are plummeting. Still, states are powering ahead with legislation and pending launches. Sportsbooks are still landing partnerships. Apparently nothing can … NFL Draft Betting Is White Hot As It Goes Virtual, Gems Could Still Abound The NFL Draft was supposed to have been held on a virtual island constructed within the fountain pool of the Bellagio in Las Vegas. Instead, it will be held in an archipelago of virtual spaces around the United States, another bi-product of the COVID-19 pandemic impacting daily lives and daily distractions. Even America’s favorite sport … William Hill CEO Says He Anticipates Return To Normalcy In Due Time The US gambling industry finds itself in uncharted territory. All professional and collegiate sports are on hiatus. Every single commercial casino (and most tribal properties) around the country has closed, causing a wave of unemployed workers. When historians look back at these few months a decade from now, they will refer to it as a … Winning At Online Roulette – The Very Best Strategy To Use Triple Rider Poker Game – The Newest In On-Line Poker Video Games Online Poker Tips – Winning Methods When Playing Poker On-Line Top Suggestions For Taking Part In Poker Online Internet Security And Online Gambling © Copyright 2022 businessmarketingservicecompany. All Rights Reserved. Blossom Pin \| Developed By Blossom Themes. Powered by WordPress.	cc/2022-05/en_middle_0078.json.gz/line24
__label__cc	0.590755	0.409245	Performance and Productivity in Parallel Programming via Processor Virtualization \| Laxmikant Kale International Workshop on Productivity and Performance in High-End Computing at HPCA (PPHEC) 2004 Repository URL: productivity We have been pursuing a research program aimed at enhancing productivity and performance in parallel computing at the Parallel Programming Laboratory of University of Illinois for the past decade. We summarize the basic approach, and why it has improved (and will further improve) both productivity and performance. The centerpiece of our approach is a technique called processor virtualization: the program computation is divided into a large number of chunks (called virtual processors), which are mapped to processors by an adaptive, intelligent runtime system. The runtime system also controls communication between virtual processors. This approach makes possible a number of runtime optimizations. We argue that the following strategies are necessary to improve productivity in parallel programming: - Automated resource management via processor virtualization - Modularity via concurrent composability - Reusability via frameworks, libraries, and multi-paradigm interoperability Of these, the first two directly benefit from processor virtualization, while the last is indirectly impacted. We describe our research on all these fronts. Laxmikant V. Kale, "Performance and Productivity in Parallel Programming via Processor Virtualization", Proc. of the First Intl. Workshop on Productivity and Performance in High-End Computing (at HPCA 10), Feb 14, 2004.	cc/2022-05/en_middle_0078.json.gz/line27
__label__cc	0.530923	0.469077	Original Short Stories, Volume 2 by Guy de Maupassant They had loved each other before marriage with a pure and lofty love. They had first met on the sea-shore. He had thought this young girl charming, as she passed by with her light-colored parasol and her dainty dress amid the marine landscape against the horizon. He had loved her, blond and slender, in these surroundings of blue ocean and spacious sky. He could not distinguish the tenderness which this budding woman awoke in him from the vague and powerful emotion which the fresh salt air and the grand scenery of surf and sunshine and waves aroused in his soul. She, on the other hand, had loved him because he courted her, because he was young, rich, kind, and attentive. She had loved him because it is natural for young girls to love men who whisper sweet nothings to them. So, for three months, they had lived side by side, and hand in hand. The greeting which they exchanged in the morning before the bath, in the freshness of the morning, or in the evening on the sand, under the stars, in the warmth of a calm night, whispered low, very low, already had the flavor of kisses, though their lips had never met. Each dreamed of the other at night, each thought of the other on awaking, and, without yet having voiced their sentiments, each longer for the other, body and soul. After marriage their love descended to earth. It was at first a tireless, sensuous passion, then exalted tenderness composed of tangible poetry, more refined caresses, and new and foolish inventions. Every glance and gesture was an expression of passion. But, little by little, without even noticing it, they began to get tired of each other. Love was still strong, but they had nothing more to reveal to each other, nothing more to learn from each other, no new tale of endearment, no unexpected outburst, no new way of expressing the well- known, oft-repeated verb. They tried, however, to rekindle the dwindling flame of the first love. Every day they tried some new trick or desperate attempt to bring back to their hearts the uncooled ardor of their first days of married life. They tried moonlight walks under the trees, in the sweet warmth of the summer evenings: the poetry of mist-covered beaches; the excitement of public festivals. One morning Henriette said to Paul: "Will you take me to a cafe for dinner?" "Certainly, dearie." "To some well-known cafe?" "Of course!" He looked at her with a questioning glance, seeing that she was thinking of something which she did not wish to tell. She went on: "You know, one of those cafes--oh, how can I explain myself?--a sporty cafe!" He smiled: "Of course, I understand--you mean in one of the cafes which are commonly called bohemian." "Yes, that's it. But take me to one of the big places, one where you are known, one where you have already supped--no--dined--well, you know--I--- -I--oh! I will never dare say it!" "Go ahead, dearie. Little secrets should no longer exist between us." "No, I dare not." "Go on; don't be prudish. Tell me." "Well, I--I--I want to be taken for your sweetheart--there! and I want the boys, who do not know that you are married, to take me for such; and you too--I want you to think that I am your sweetheart for one hour, in that place which must hold so many memories for you. There! And I will play that I am your sweetheart. It's awful, I know--I am abominably ashamed, I am as red as a peony. Don't look at me!" He laughed, greatly amused, and answered: "All right, we will go to-night to a very swell place where I am well known." Toward seven o'clock they went up the stairs of one of the big cafes on the Boulevard, he, smiling, with the look of a conqueror, she, timid, veiled, delighted. They were immediately shown to one of the luxurious private dining-rooms, furnished with four large arm-chairs and a red plush couch. The head waiter entered and brought them the menu. Paul handed it to his wife. "What do you want to eat?" "I don't care; order whatever is good." After handing his coat to the waiter, he ordered dinner and champagne. The waiter looked at the young woman and smiled. He took the order and murmured: "Will Monsieur Paul have his champagne sweet or dry?" "Dry, very dry." Henriette was pleased to hear that this man knew her husband's name. They sat on the couch, side by side, and began to eat. Ten candles lighted the room and were reflected in the mirrors all around them, which seemed to increase the brilliancy a thousand-fold. Henriette drank glass after glass in order to keep up her courage, although she felt dizzy after the first few glasses. Paul, excited by the memories which returned to him, kept kissing his wife's hands. His eyes were sparkling. She was feeling strangely excited in this new place, restless, pleased, a little guilty, but full of life. Two waiters, serious, silent, accustomed to seeing and forgetting everything, to entering the room only when it was necessary and to leaving it when they felt they were intruding, were silently flitting hither and thither. Toward the middle of the dinner, Henriette was well under the influence of champagne. She was prattling along fearlessly, her cheeks flushed, her eyes glistening. "Come, Paul; tell me everything." "What, sweetheart?" "I don't dare tell you." "Go on!" "Have you loved many women before me?" He hesitated, a little perplexed, not knowing whether he should hide his adventures or boast of them. She continued: "Oh! please tell me. How many have you loved?" "A few." "I don't know. How do you expect me to know such things?" "Haven't you counted them?" "Of course not." "Then you must have loved a good many!" "Perhaps." "About how many? Just tell me about how many." "But I don't know, dearest. Some years a good many, and some years only a few." "How many a year, did you say?" "Sometimes twenty or thirty, sometimes only four or five." "Oh! that makes more than a hundred in all!" "Yes, just about." "Oh! I think that is dreadful!" "Why dreadful?" "Because it's dreadful when you think of it--all those women--and always --always the same thing. Oh! it's dreadful, just the same--more than a hundred women!" He was surprised that she should think that dreadful, and answered, with the air of superiority which men take with women when they wish to make them understand that they have said something foolish: "That's funny! If it is dreadful to have a hundred women, it's dreadful to have one." "Oh, no, not at all!" "Because with one woman you have a real bond of love which attaches you to her, while with a hundred women it's not the same at all. There is no real love. I don't understand how a man can associate with such women." "But they are all right." "No, they can't be!" "Yes, they are!" "Oh, stop; you disgust me!" "But then, why did you ask me how many sweethearts I had had?" "Because----" "That's no reason!" "What were they-actresses, little shop-girls, or society women?" "A few of each." "It must have been rather monotonous toward the last." "Oh, no; it's amusing to change." She remained thoughtful, staring at her champagne glass. It was full-- she drank it in one gulp; then putting it back on the table, she threw her arms around her husband's neck and murmured in his ear: "Oh! how I love you, sweetheart! how I love you!" He threw his arms around her in a passionate embrace. A waiter, who was just entering, backed out, closing the door discreetly. In about five minutes the head waiter came back, solemn and dignified, bringing the fruit for dessert. She was once more holding between her fingers a full glass, and gazing into the amber liquid as though seeking unknown things. She murmured in a dreamy voice: "Yes, it must be fun!" The Classical Library, This HTML edition copyright ©2001.	cc/2022-05/en_middle_0078.json.gz/line30
__label__wiki	0.755381	0.755381	Anchange Productions LLC presents Palo Alto: a collaborative effort of young filmmakers from all over the country. It is spearheaded by three Palo Alto natives, and is meant to showcase the lifestyles of their generation. The movie was shot on location in Palo Alto with the help of many supporting community members. This website is devoted to the production of Palo Alto and it’s here that you will find all the latest news, cast and crew bios, production blog entries, production photo galleries, and hopefully a lot more! Screenings at University of Washington, Seattle University, and Berkeley this month. Check the schedule here. Screenings at Middlebury College, Columbia University, and New York University have been added to the schedule in February. More to come. Check the schedule here. San Jose screenings were packed on both nights, with huge support and a positive reaction from the audience. Due to the success of those screenings, an encore screening scheduled for Januaray 22nd has been arranged! CineLux Almaden Cinema (2306 Almaden Road, San Jose) at 9:00pm The filmmakers will be hositing the Bay Area Premiere of PALO ALTO in San Jose! The screenings are at the CineLux Almaden Cinema (2306 Almaden Road, San Jose)at 9:15pm on January 14th and 15th. See you there! New Facebook Fan page activated, become a fan to keep updated with screening information and other important events! DVD release date set for February 17th, 2009. Pre-orders can be made on Amazon.com. More screenings added! New review from DVD Verdict. Trailer posted. New blogs posted. Thank you to all our sponsors: spam addressed from this domain name does not originate from paloaltothemovie.com please send legitimate inquiries to webmaster@paloaltothemovie.com Copyright 2006 Anchange productions llc. all rights reserved Web design: www.adamkurihara.com	cc/2022-05/en_middle_0078.json.gz/line32
__label__cc	0.736395	0.263605	Category Archives: Potassium (KV) Channels Through the clinical perspective, the synergistic ramifications of simvastatin with book AR targeting agents, such as for example abiraterone and enzalutamide acetate, in treating CRPC patients might receive more attention Posted on September 28, 2021 by Cindy Olson Through the clinical perspective, the synergistic ramifications of simvastatin with book AR targeting agents, such as for example abiraterone and enzalutamide acetate, in treating CRPC patients might receive more attention. appearance amounts by (a) traditional western blot evaluation and (b) the percentage of cell viabilities regarding to simvastatin treatment between your control and LIN28B-overexpression Computer3 cells. (TIF) pone.0184644.s003.tif (587K) GUID:?F74352C7-C213-4BFF-9AC8-8C6F1623AEC9 Data Availability StatementAll relevant data are inside the paper and Avanafil its own Supporting Details files. Abstract We analyzed the anti-cancer results and molecular system of simvastatin in individual castration-resistant prostate tumor (CRPC) cells, centered on and its own focus on molecule especially, microRNA (miRNA) among the many focus on genes of NF-B. A individual CRPC cell range (Computer3) was found in the existing research. Gene appearance patterns were examined using genuine time-PCR and traditional western blot analysis. CCK-8 assay was useful for evaluating cell proliferation and viability, and a clonogenic assay was followed to judge clonal proliferative features. Induction of apoptotic cell loss of life was analyzed via movement cytometry. Little interfering RNA (siRNA) and short-hairpin RNA (shRNA) had been useful for manipulating the appearance of genes appealing. Computer3 showed higher appearance degrees of and lower appearance degrees of miRNAs relatively. Simvastatin treatment inhibited cell viability and clonal proliferation within a dose-dependent way significantly. Significantly, the downregulated miRNA family members was restored after simvastatin treatment. We observed that individual CRPC cells transfected with miRNAs additional. Finally, dual treatment with simvastatin and an inhibitor (CAPE) synergistically induced apoptotic cell loss of life, along with reduced amount of appearance, and recovery of miRNlevels. Our data illustrate that simvastatin incredibly inhibits the development of individual CRPC cells by suppressing and and eventually upregulating miRNAs. Furthermore, concurrent treatment with simvastatin and an NF-B inhibitor suppressed the development of individual CRPC cells synergistically, suggesting a novel therapeutic approach for human CRPC treatment. Introduction The incidence of prostate cancer (PCa) has increased rapidly over the decades and has become a crucial health issue world-wide [1]. PCa gradually progresses over time and shows a low cancer-specific mortality [2]. However, if patients with PCa progress to castration-resistant prostate cancer (CRPC), they mostly die within 24 months after the diagnosis of CRPC [3]. Although systemic chemotherapy and/or Avanafil androgen receptor (AR)-targeted agents are regarded as treatments of choice for CRPC, treatment is hindered by adverse effects and drug-resistance [4]. In this context, development of alternate agents with good efficacy and minimal adverse effects is urgently needed for treating patients with CRPC. One of the promising approaches is targeting the aberrant metabolism of cancer cells without damaging normal cells by using specific agents that control metabolic disorders, such as statins [5]. Statins primarily inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase within the intracellular cholesterol biosynthesis pathway, and are widely used for treating hypercholesterolemia [6]. In addition to the accumulating evidence for the anti-cancer efficacy of statins, we have found that human CRPC cells (PC3 and DU145) show high expression of NF-B and that simvastatin treatment induces apoptotic cell death by downregulation of activated NF-B signaling [7]. However, the detailed molecular mechanisms underlying the anti-cancer effects of simvastatin remain unclear. Among various downstream genes of the signaling pathway, has received great interest as a key oncogene, because it specifically Avanafil blocks the biogenesis of and its target molecule, signaling pathway can be restored by statin treatment and suppress the growth and proliferation of human CRPC cells. Materials and methods Cell culture and reagents PC3, a well-known human CRPC cell line, was used in the current study. PC3 was purchased from the American Type Culture Collection (Rockville, MD, USA). This cell Avanafil line was Avanafil cultured in RPMI-1640 medium (WELGENE, Gyeongsan, Korea) supplemented with 10% fetal bovine serum (FBS; BIOWEST, Nuaill, France), 1% penicillin-streptomycin (Thermo Fisher Scientific, MA USA), and 1% nonessential amino acids (Invitrogen) at 37C with 5% CO2. The details of the primers and primary antibodies used in our study are presented in Tables ?Tables11 and ?and2,2, respectively. Table 1 Rabbit Polyclonal to FRS3 Details of the primary antibodies used in the present study. compared to those. Posted in Potassium (KV) Channels Supplementary Materials Supplementary Material supp_127_11_2528__index Supplementary Materials Supplementary Material supp_127_11_2528__index. repolarize because of its following persistent move due to nuclear rotation mediated by cytoplasmic dynein light intermediate string 2. alternates between fast continual movements mediated by its flagella dominantly revolving counterclockwise and tumbling occasions mediated from the flagella transiently revolving clockwise (Berg, 1993). Likewise, an array of eukaryotic cells also alternative between advancing shows of fast and continual motions and hesitation shows of low acceleration and low persistence. Nevertheless, the molecular system that settings the powerful adjustments in morphology, persistence and acceleration of migratory Rabbit Polyclonal to Ezrin (phospho-Tyr478) cells remains to be unclear. During arbitrary mesenchymal migration (i.e. simply no chemotactic gradients), cells modification their morphology consistently, dynamically switching between elongated and around morphology (K?ppen et al., 2006). Keeping cell polarity by placing the nucleus is essential for mesenchymal cell migration correctly, which is powered by repeated cycles of polarization, protrusion, translocation and retraction from the cell (Bretscher, 2008; Webb and Horwitz, 2003; Morris, 2000; Petrie et al., 2009). Although nuclear motions mediated by microtubule-dependent procedures have been researched thoroughly (Cadot et al., 2012; Lee et al., 2005; Holzbaur and Levy, 2008; Umeshima et al., 2007; Holzbaur and Wilson, 2012), recent function has exposed that actin filaments will also be involved with Diflunisal nuclear dynamics in migrating cells (Gomes et al., 2005) through particular connections between your nuclear envelope as well as the actin cytoskeleton (Starr and Fridolfsson, 2010). In polarized cells, F-actin is involved with preliminary symmetry-disrupting procedures that react to exterior stimuli rapidly; microtubules stabilize the asymmetry produced by actin filament dynamics (Li and Gundersen, 2008). Specifically, transmembrane actin-associated nuclear (TAN) lines constructed Diflunisal with cytoplasmic actin filaments and LINC (linkers of nucleoskeleton and cytoskeleton) complicated proteins nesprin-2 huge (nesprin-2G, the biggest isoform encoded from the gene) and Sunlight2 have already been found to allow reward movement from the nucleus in migrating fibroblasts in the wound curing assay (Luxton et al., 2010). Lately, we characterized extremely purchased actomyosin filament bundles that firmly cover the apical areas from the interphase nucleus and particularly bind the nuclear envelope as well as the nuclear lamina through LINC complexes in an array of adherent cells, termed the perinuclear actin cover (or actin cover) (Khatau et al., 2009; Kim et al., 2013). The actin-cap materials and their terminating focal adhesions become key the different parts of the physical pathway that changes extracellular stimuli into intracellular indicators (Kim et al., 2013; Kim et al., 2012). Diflunisal As cell migration requires continuous mechanosensation, and different physiological and pathological procedures C such as for example cancers metastasis and embryonic advancement C are extremely reliant on cell motility (Chaffer and Weinberg, 2011; Massagu and Gupta, 2006; Thiery et al., 2009; Wirtz et al., 2011), we hypothesized how the actin cover would regulate cell migration. Right here, our outcomes indicate how the powerful development and dissolution from the actin cover tightly settings the timing and event of Diflunisal fast persistence movements in fibroblast migration. Furthermore, this research reveals how the translocation and rotation from the interphase nucleus are controlled by the powerful attachment from the actin cover towards the nuclear envelope via KASH-SUN relationships in the perinuclear space between your inner and external nuclear membranes. Outcomes The actin cover settings cell migration During arbitrary migration, mesenchymal cells such as for example mouse embryonic fibroblasts (MEFs) consistently modification their morphology, dynamically switching between an elongated and a curved shape. We’ve recently demonstrated that cell form controls nuclear form through the forming of the actin cover (Khatau et al., 2009), which can be organized in the apical surface area from the nucleus (Fig.?1A and supplementary materials Film 1). In the lack of chemotactic gradients, the migration of adherent cells, including fibroblasts, endothelial myoblasts and cells, which can type an structured actin cover (Kim et al., 2013), resembles a continual random-walk that includes intermittent highly continual fast movements and slow movements of low persistence (Fig.?1B and supplementary materials Film 2). Confirming the prior outcomes that selective. These results indicate a role for Med12 in the regulation of fibronectin, collagen type 1, and PAI-1 protein expression in HuLM cells Posted on June 20, 2021 by Cindy Olson These results indicate a role for Med12 in the regulation of fibronectin, collagen type 1, and PAI-1 protein expression in HuLM cells. Open in a separate window EML 425 Figure 5. Effect of knockdown on manifestation of fibrosis-associated proteins in hUF cells. humans and rats showed the mammalian target of the rapamycin pathway is definitely highly upregulated in both human being and rat tumors, and UF growth is dependent upon the activation of mammalian target of the rapamycin signaling (11). The study by Mittal (12) also shown that conditional manifestation of a common Med12 variant promotes leiomyoma formation in the uterus and genomic instability inside a murine model. The Mediator is definitely a large complex of 30 subunits and a component of the complex mechanisms that regulate eukaryotic transcription and therefore control organism development and homeostasis (13, 14). The Mediator complex is definitely conserved in all eukaryotic organisms and required for the transcription of almost all genes (15, 16). The Mediator complex interacts directly with a number of transcription factors to facilitate RNA polymerase II recruitment to target genes (17). Subunits are necessary for all functions of the Mediator, including the connection with the polymerase II machinery or maintenance of the complex, which are important for cell survival (18, 19). Med12 has been linked to general functions of the complex and to specific relationships with transcription factors. Med12 is definitely a subunit of the Cdk8 kinase module and has been shown to function like a transducer of Wnt/gene knockout shown that it is vital for early mouse embryogenesis and for canonical Wnt and Wnt/planar cell polarity signaling pathways (24). It has previously been shown that receptor signaling (26). Recently, Prenzel (27) exposed that Med12 is required for the manifestation of estrogen receptor (ER)-in human being breast malignancy cells. Med12 offers been shown to be overexpressed in pancreatic malignancy, whereas knockdown of Med12 manifestation inhibits cell cycle progression in pancreatic malignancy cells (28). Although prior studies have suggested a role for Med12 in association with the canonical Wnt/gene manifestation in immortalized hUF EML 425 (HuLM) cells using a lentivirus-based gene-specific RNA interference EML 425 (RNAi) strategy. Suppression of Med12 manifestation affects several signaling pathways, such as Wnt/signaling, sex steroid receptor signaling, as well as growth-associated and fibrosis-associated proteins in HuLM cells. Materials and Methods Cell lines EML 425 and cultures The HuLM cell collection was a nice gift of Dr. Darlene Dixon (National Institute of Environmental Health Sciences, Study Triangle Park, NC), as previously explained (29). These cells were grown in clean muscle cell tradition medium with 5% fetal bovine serum at 37C inside a humidified atmosphere of 5% CO2, as previously explained (30). Primary human being UF cells used in this study were explained in our earlier paper (31). Reagents and antibodies Antibodies are demonstrated in Table 1. TGF-antibody Santa Cruz Biotechnology (Catalog # sc-8002)Mouse monoclonal 500Progesterone receptor-A (PR-A)Anti-PR-A antibody Santa Cruz Biotechnology (Catalog # sc-7208)Rabbit polyclonal 500Progesterone receptor-B EML 425 (PR-B)Anti-PR-B antibody Santa Cruz Biotechnology (Catalog # sc-538)Santa Cruz Biotechnology (Catalog # sc-538)Rabbit polyclonal 500Plasminogen activator inhibitor 1 (PAI-1)Anti-PAI-1 antibody Santa Cruz Biotechnology (Catalog # sc-8979)Rabbit polyclonal 500Smad4Smad4Anti-Smad4 antibody Santa Cruz Biotechnology (Catalog # sc-7966)Mouse monoclonal 500Phospho-ERK Antigene was silenced by stable manifestation of geneCspecific short hairpin RNA (shRNA) in HuLM cells. HuLM cells provide an appropriate model to determine the function of Med12 in UF cells. Lentivirus plasmid constructs that contain knockdown main fibroid cell populations. These polyclonal cells were then tested for manifestation as well as manifestation of Wnt4 and knockdown cells or scrambled control cells were seeded onto 12-well cells tradition plates from BD Biosciences (Sumter, SC) and incubated over night. Cells were then cultured in phenol-free Dulbeccos altered Eagle medium (DMEM)/F12 medium comprising 10% charcoal-stripped fetal bovine serum. Cultures were replenished every other day time with new conditioned press. Cells were counted at day time 0, day time 2, day time 4, and day time 8. Averaged cell figures from triplicate wells were used for the data graph. Each data point is the imply standard deviation of triplicate wells (n = 3). Western blot analyses knockdown cells and scrambled control cells were cultured CARMA1 in 10-cm cells culture dishes. Preparation of cell lysates and Western blot analyses were performed, as previously explained (31C33). The. Accumulating evidence shows that long non-coding RNA (lncRNA) sprouty4-intron transcript 1 (lncRNA SPRY4-IT1) plays a vital role in the development of breast cancer Accumulating evidence shows that long non-coding RNA (lncRNA) sprouty4-intron transcript 1 (lncRNA SPRY4-IT1) plays a vital role in the development of breast cancer. survival time, while RNAi-mediated knockdown of EZH2 may induce the expression of SPRY4-IT1. Additionally, Xie et al. [14] showed that SPRY4-IT1 played an important role in epithelialCmesenchymal transition via regulating the expression of E-cadherin and vimentin. Nevertheless, the underlying mechanism of lncRNA SPRY4-IT1 in breast cancer remains unclear. Previous studies exhibited that N-terminal polypeptide derived from viral macrophage inflammatory protein II (NT21MP) competed effectively with CXCR4, SDF-1, and induced cell death [15,16]. NT21MP reversed the EMT in breast malignancy cells via PDGFR [17] and exerted anti-glioma effect by specifically combining with CXCR4 [18]. In this study, we focussed on whether SPRY4-IT1 was involved in tumorigenesis and explored how NT21MP contributed to anti-tumor effects by regulating SPRY4-IT1 to provide novel biomarkers for breast cancer therapy. Methods and Materials Cell culture Individual breasts cancers cell lines such as for example SKBR-3, MCF-7, BT-11 MDA-MB-231 had been bought from Shanghai Cell Institute of Chinese language Lypd1 Academy of Research. MDA-MB-231, which overexpressed CXCR4 cell series (pcDNA-CXCR4-MDA-MB-231), was induced by our lab and continues to be identified previously. The cells had been cultured in DMEM moderate supplemented with 10% FBS and preserved at 37C within a humidified atmosphere with 5% CO2. When cell confluence reached 80C90%, 0.25% trypsin was employed for digestion and passage. All tests had been performed through the use of logarithmic growth stage cells. Total RNA removal and quantitative real-time PCR The full total RNA from the cell lines had been isolated with TRIzol (Invitrogen) based on the producers guidelines and reversed transcription into cDNA with a Revert Help Initial Strand cDNA Synthesis Package (Thermo Scientific, U.S.A.). The quantitative real-time reverse-transcription PCR (qRT-PCR) was performed to testify the amount of mRNA and relative to previous method [17]. The primers found in PCR are proven in Desk 1. Desk 1 The sequences of primers beliefs 0.05 are believed as significant. Outcomes Ramifications of NT21MP and depletion or overexpression of CXCR4 in the appearance of SPRY4-IT1 in breasts cancer cells On the other hand with control group, depletion of CXCR4 could down-regulate appearance of SPRY4-IT1 (Body 1A). In the pcDNA-CXCR4 group, the appearance of SPRY4-IT1 had not been statistically significant weighed against the control group because of low appearance of SDF-1. These total results showed the fact that expression of SPRY4-IT1 was linked to SDF-1/CXCR4 axis. Besides, NT21MP and SDF-1 treatment were put on additional validate the function of NT21MP BT-11 in SPRY4-It all1. As proven in Body 1B, SDF-1 could promote the appearance of SPRY4-IT1, while NT21MP can inhibit SDF-1-induced up-regulation of SPRY4-IT1 appearance. Open in another window Body 1 Ramifications of NT21MP and depletion or overexpression of CXCR4 in the appearance of SPRY4-IT1 in breasts cancer cells(A) The consequences of depletion or overexpression of CXCR4 in the appearance of SPRY4-IT1. (B) The affects of NT21MP in the appearance of SPRY4-IT1. Data had been offered as mean S.D. of three impartial experiments. or ##or or or ##or @@or or and ##or ##or @@or or **or ##or @@or study in order to further explore the molecular activity of SPRY4-IT1, which involved in NT21MP anti-tumor activity. Accumulating evidence has exhibited that SKA2 participated in cell cycle regulation and tumorigenesis. Cao et al. [40] reported that this expression of SKA2 and miR-301 may inhibit colony forming in A549 cells. In the present study, we examined the level amongst SKA2, SPRY4-IT1, and NT21MP, confirming was the target BT-11 gene of SPRY4-IT1, and the regulation of SPRY4-IT1 on biological activity in breast malignancy cells was partially achieved through SKA2. At the same time, SKA2 may take part in NT21MP, which regulates tumor biological activity. Although we have exhibited NT21MP can exert its anti-breast malignancy effect by regulating SPRY4-IT1 and SKA2, the specific mechanism has not been further analyzed. Taken together, our findings offered that NT21MP can regulate appearance degree of SPRY4-IT1 by preventing SDF-1/CXCR4 axis and eventually, activating SKA2 and playing an integral role in breasts cancer tumor cell apoptosis (Body 10). These total results claim that SPRY4-IT1 is actually a appealing biomarker for scientific chemotherapy. Open in another window Body 10 A model for SPRY4-IT1 in breasts cancer cells is certainly proposed Conclusion Today’s study demonstrated. Supplementary MaterialsTable_1 Posted on December 22, 2020 by Cindy Olson Supplementary MaterialsTable_1. EBVC B-cells. Also, a prevalence of cytotoxic T-cells over Th2-like cells was associated with an elevated viral insert. These observations indicate contribution of B- and Th2-like cells towards the control of principal EBV infections. 35% of Compact disc8+ cells had been differentiated Compact disc8+TBET+ cells, discovered in post-capillary venules frequently. An inverse relationship was observed between your numbers of Compact disc8+TBET+ cells and viral insert recommending a pivotal function for these cells in the control of principal EBV infections. Our results supply the basis for an improved understanding of Dafadine-A immune system reactions in EBV-associated tumors. evaluation of some IM tonsils to characterize EBV infections, tissue microenvironment structure and immune system response signature. Methods Tissues Formalin-fixed paraffin-embedded (FFPE) tissue blocks from 16 Rabbit Polyclonal to STAT1 (phospho-Tyr701) tonsils with a diagnosis of IM were included. All patients were submitted to tonsillectomy for severe obstructive tonsillitis. Age ranged from 7 to 31 years (median 20 years). For analysis, patients were categorized in two age groups (19 years and 20 years). Fourteen cases (87.5%) were male and 2 cases (12.5%) female. All cases were selected from your archives of the Institute of Pathology, Unfallkrankenhaus Dafadine-A Berlin. All materials were submitted for diagnostic purposes and were anonymised. No tissue samples have been collected solely for the purpose of this study. The FFPE tissue blocks were used in accordance with national ethical principles and Declaration of Helsinki, dispensing a compulsory statement from an ethics committee, according to local and national guidelines. All histological diagnoses were examined before inclusion in this study. A Dafadine-A Tissue arrayer device (Beecher Instrument, Estonia/USA) was used to assemble the tissue microarray (TMA) blocks. From each case, four 2-mm-diameter cores selected from four different areas rich in EBER+ cells were included. To ascertain that this cores contained representative numbers of EBV-infected cell, all TMAs were subjected to EBER-specific hybridization again (EBER-ISH, observe below). All cases showed cores with high numbers of EBER+ cells/mm2 (from 105 to 1 Dafadine-A 1,006 EBER+ cells/mm2, median: 390 cells/mm2). EBV Detection Latent EBV contamination was determined in all cases by hybridization (ISH) for EBERs (EBER-ISH) as explained previously (26), employing diaminobenzidine (DAB) chromogen (Zytomed Systems, Berlin, Germany) as chromogen. The latent proteins were evaluated by immunohistochemistry (IHC) as explained previously, using the antibodies against EBNA1 (clone 1H4, kind gift from Dr. Kremmer, Munich, Germany), EBNA2 (clone PE2, kind gift from Dr. M. Rowe, Birmingham, UK), LMP1 (clones CS1-4, Zytomed Systems) and BZLF1 (clone BZ1, Santa Cruz, Dallas, USA) (27). Double EBER-ISH and Immunohistochemistry To evaluate the number of B cells infected by EBV, a double EBER-ISH and IHC assay was used to discriminate EBV-infected B cells (EBER+Compact disc20+) from EBV-negative B cells (EBERC Compact disc20+). Following conclusion of the EBER-ISH assay as defined above, antigen retrieval was performed by heat therapy within a pressure-cooker for 1 min instantly, using citrate buffer pH 7.6. A preventing step was executed, using Blocking Option contained in the AP Polymer Program (Zytomed Systems), based on the manufacturer’s guidelines. Anti-CD20 was used as principal antibody and was incubated within a damp chamber at 4C overnight. Following manufacturer’s guidelines, immunodetection was performed with AP Polymer Program (Zytomed Systems) within a moist chamber at area temperature, using Vector Blue Alkaline Phosphatase Substrate Package III (Vector Laboratories) under microscopic control. Supplementary MaterialsFig_S1A_rrz088 Posted on November 6, 2020 by Cindy Olson Supplementary MaterialsFig_S1A_rrz088. proportion (SER) was determined. The clonogenic assay was used to compare the effect of multi-fractioned irradiation between 8?Gy/1 fraction (fr) and 8?Gy/4 fr. H2AX, Rad51, BRCA1, BRCA2 and 53BP1 foci were recognized via immunofluorescence. Olaparib exhibited an SER of 1 1.5C1.7 on PBT. The same sensitizing effect was exhibited in multi-fractioned irradiation, and the combined use improved the manifestation of double-strand breaks and homologous recombination-related genes in an additive manner. Such additive effects were not observed on non-homologous end joining-related genes. We shown that olaparib has a high sensitizing effect on PBT in platinum- and radiation-resistant esophageal malignancy cells. Our results suggest a potential medical software of olaparib-proton irradiation (PT) against platinum- and radiation-resistant esophageal malignancy. Keywords: esophageal malignancy, proton, radiation, PARP, BRCA Intro Chemoradiotherapy for esophageal malignancy The effectiveness of chemoradiotherapy in combination with 5-fluorouracil (5-FU) and cis-diamminedichloroplatinum (II) (CDDP) was shown in 1999; since then, it has served as a standard treatment for esophageal malignancy [1, 2]. Thus far, phase III tests that significantly lengthen survival compared with combined 5-FU, CDDP and radiotherapy (FP-RT) have not been reported. Several combination therapies including taxan, a cytotoxic drug that focuses on microtubules, and gefitinib and cetuximab, two medicines that target the EGFR, have been tested. However, these drugs have not displayed superiority to FP-RT in medical studies [3, 4]. As a result, finding an alternative solution approach for dealing with esophageal cancers refractory to FP-RT is still difficult [2, 5]. As the esophagus is normally a located thoracic framework, there has to be an equilibrium between providing the cytotoxic agent to the mark at an properly high dosage and reducing the dosage to nearby vital structures. Excessive rays received by these HDAC10 vital structures, the center and lungs especially, can lead to significant toxicities medically, including pneumonitis, pericarditis and myocardial infarction. Although technical improvements in photon RT delivery, such as for example intensity-modulated RT, possess decreased the chance of such toxicities, mounting proof indicates that additional risk reductions may be accomplished with proton beam therapy (PBT) [6]. Nevertheless, reviews on photon therapy Mcl1-IN-12 are a lot more common than reviews on medications that display radiosensitizing effects. Presently, chemotherapy coupled with PBT uses therapies which have been found in mixture with photon therapy previously, such as for example CDDP and 5-FU, and so are not predicated on apparent evidence. As a result, the elucidation of sensitizers and their systems in the framework of proton beams is essential. DNA-damaging realtors have already been reported undertake a novel system of actions [7 lately, 8]. The poly (ADP-ribose) polymerase (PARP) category of proteins can convert single-strand breaks Mcl1-IN-12 (SSBs) into double-strand breaks (DSBs), that are amenable to correct by homologous recombination (HR). Appropriately, PARP inhibitors can induce artificial lethality in cancers cells having vulnerable HR fix abilities, such as for example BRCA-mutated cancers. Recently, PARP inhibitors have been Mcl1-IN-12 shown to show high radiosensitizing effects in prostate malignancy, pancreatic malignancy and breast tumor cell lines [6, 8]. An increasing number of studies have investigated these variations which cause different biological effect between proton and photon in detail at the cellular and molecular levels [9]. Photon-triggered DSBs are primarily repaired by non-homologous end becoming a member of (NHEJ), whereas proton-induced DSBs are repaired by HR [10]. Protons and PARP inhibitors, which both stimulate HR-dependent DSB restoration, are consequently of particular restorative relevance because they may show a strong sensitizing effect. Olaparib is an FDA-approved drug that was recently reported to exhibit sensitization in pancreatic malignancy and lung adenocarcinoma cell lines [11]. In Japan, olaparib and PBT received insurance authorization in 2018, and development of its adaptation is definitely expected in the future. Comprehensive analyses suggest Mcl1-IN-12 that esophageal malignancy displays abnormalities in DSB restoration pathways such as PARP and BRCA. Inside a TCGA dataset, we found that 8.2% have BRCA1 and BRCA2 mutations or duplicate number modifications and 1.5% of patients possess PARP1 copy number alterations (see online supplementary Amount S1). Furthermore, the various other genes, such as for example Rad and ATR 51, that are essential to correct DNA harm by irradiation possess mutations or duplicate amount alterations also. Therefore, remedies that focus on DSBs are anticipated. However, research that Mcl1-IN-12 evaluate fractionated irradiation with regular therapies such as for example 5-FU and CDDP and molecular systems are rare; this given information would supply the rationale for clinical trials. In today’s study, we showed the result of PBT coupled with olaparib on esophageal cancers cell lines and looked into the underlying system of this solution to establish an.	cc/2022-05/en_middle_0078.json.gz/line34
__label__cc	0.744056	0.255944	Oh, belt up Betty is hiding under the covers. Beneath the purple velvet throw, a shape on my bed squirms and stifles giggles. Grace and I, advancing on tiptoe on either side, glance at each other and nod conspiratorially, smiling. With a whoop, we dash to reveal her but at just that moment my two year-old daughter flings back the covers and sits bolt upright, hair a perfect dandelion of static, shouting and pointing at us: "Found oo!" We collapse on our knees, protesting that that's not how the game goes. Beaming and magnanimous, Betty beckons us in. "C'mon: hiding," she says to Grace and me. We get into bed on either side of her and she flings the coverlet over our heads. In the dark, everyone's giggles subside. In the silence I can hear the slow breathing of my big girl and the rhythmic wet tug of Betty sucking her fingers. I can smell the top of Betty's head and the sweetness of her breath. Grace's hand curls around to find mine and I kiss her slender fingers, stroking a rough patch over one knuckle. Cocooned and peaceful I reflect on my day, which has been thoroughly rotten but also revelatory. It started this morning as I travelled to work pre-dawn, surrounded by grey commuters, watching warped reflections in the curved train window and fretting about the state of my bank account. As I sat, stiffly working through the same sums in my head and failing repeatedly to find a bigger total, my co-travellers shook out newspapers and gravely consumed articles about economic crisis, spiralling debt, political unrest. I thought about my below-inflation pay rise (make that sub-zero, below-inflation pay rise) and the contrasting mountainous peaks of our household outgoings. Beside me a young man read a book called "Think and Grow Rich", underlining in blue pen passages about using the subconscious to bring lucrative ideas to fruition. His fingernails were bitten to the quick. The time was six thirty in the morning. The carriage smelled of recession. Work was better, enlivened by lovely colleagues and appreciation of what I do and the kind of black-humoured desk banter that supports and salves and acknowledges the really gloomy stuff only by poking fun at it. But then there were the phone calls, the same tedious, depressing phone calls. The latest meeting, the latest conversation about the latest report, the latest tiny, tiny, suggestion of a baby-step towards progress. Redoing the numbers in my head again and wondering about paying for extra help if it might help Grace faster. Redoing my work shifts in my head again and wondering how to ask for the next bit of time off for the next appointment, or presentation for parents, or training that I dare not miss as I attempt to garner information and points. Debating carrying my tombstone-heavy laptop all the way home again in case Grace has had another bad day at school and I have to work at the kitchen table tomorrow in between visits to the school office. And then someone told me to belt up. Have you ever asked for help, wailed about being stressed, gone on and on and on about the injustice and the fatigue of it, got angrier and angrier and then been told: "Oh, belt up"? Neither had I. Boy, was it liberating. Because actually, it's what everyone else has been saying all along. Translated, the government has long been telling me to belt up, to tighten my belt, to cut back, to manage. The local authority has long been telling me to belt up, to go away, to take my complaints and my needy daughter and just put a sock in it. The school has said to me belt up, we know, we're working on it, we can't perform miracles. In the business world in which I work the current mantra is: look, it's rough out there, we like you, it's time for everyone to make sacrifices: now take this and belt up. It's just that so far everyone has been a bit more polite about it than that and I, sap that I am, have responded to their bland words by wrinkling my nose and making vague noises of displeasure and shuffling away to groan quietly to myself. Faced now with a direct insult I pass quickly through shock, then outrage, then anger so pure I think I might have a heart attack. But now I can see the world for what it really is and the true nature of the abuse that's been coming my way for a while now. It's not personal. It just is. I can laugh and shake my head and counter with the knowledge that I have a secret weapon that will see me through. Later this evening, when the girls are asleep and my husband is back from work, I will go running. Quickly, before I can change my mind, I will change into my thermal long-sleeved top, my running tights, my shorts; I will don jumper and hat and socks. Outside it will be black and cold and squally with rain. I will wince and angle my head to avoid the worst of it and I will run and run and run and sometimes when the traffic is loud I will shout rude words and roar like a madwoman and no-one will hear me. But I will not be silenced and I will finish this marathon. Jane Badger 10 November 2011 at 17:42 You go - don't give up. I love your writing, and every time I read one of your posts, you open new windows on what it is like to be you and your family. Is There Anybody There? Feeling the fear, and doing it anyway	cc/2022-05/en_middle_0078.json.gz/line39
__label__cc	0.682043	0.317957	Hank Shocklee Seen Outside Def Jam Offices: “Will Produce Thundering Wall Of Sound For Food.” Jess • New York London Paris Munich • Pop • Post a comment • 430 views Terminally out of step, Chuck D and his attendant hangers on (I wonder if they still call themselves the “Security of the First World” post 9-11) have announced a contest allowing scrawny white boys with a copy of ProTools the world over the chance to produce the new (old) P.E. record. As if that wasn’t goofy enough, the secondary hook is that they are old songs; every week starting in July, they’re going to post newly recorded vocals for classic Public Enemy tracks to their website for then renovation. Spake the Righteous Thunder himself: “We want to hear everything from electronica to metal, slack-key to Brazilian jazz, even bluegrass and country,” and “the Motowns, STAX, Atlantic, Chess, SUN, and even the early rap labels Enjoy, Profile, Tommy Boy and yes Sugarhill’ rode on the spontaneity of cutting sounds, on what was happening right then on the street, and getting it back out.” What do you wanna guess they’re all gonna sound like a. The Neptunes, b. Public Enemy records, c. DJ Shadow, or d. Kid606-style plunderphonia? Now if you’ll excuse me I have to get back to my reworking of “Terminator X Speaks With His Hands.” B*WITCHED - "Blame It On The Weatherman" 3 Oct 2014 Arriving a few weeks after Britney, “Blame It On The Weatherman” could be a sad afterthought, forgotten jetsam from a swept-away moment like Frank Ifield’s “I’m Confessin’”, his last number… The Sound Barrier Podcast: 5: Wall-E / The Red Turtle 31 May 2017 On the fifth Sound Barrier we have no guests, but an extremely animated discussion about - oh, did you see what I did there. We are comparing a Pixar classic… King William’s College Kwizz 2019. FT Round 5 6 Jan 2020 1 what was Best and Goes Farthest? 2 which product held the fifth Golden Ticket? 3 what did Vianne open in Lansquenet-sous-Tannes? 4 which Gammel Strand grøntsager put marzipan to good use? 5 Desperation, Pacification, Expectation, Acclamation… It's A Metamorphosis 10 Jun 2015 This is a reprint from my Tumblr, from a meme where people asked for album reviews. This was for Very, by the Pet Shop Boys (and Bilingual too, as it… U2 - "Discotheque" 11 Feb 2014 A year before this, U2 just missed the top with one of their best singles: “Hold Me, Thrill Me, Kiss Me, Kill Me”, a glam tidbit recorded for a Batman… EMINEM - "Without Me" 14 Sep 2017 Eminem produced “Without Me” himself, and the sound of this song is the best thing about it, a thick, soupy, snaky bassline and a brutally four-square beat. Ironic that this… FIVE - "Keep On Movin'" 14 Dec 2014 Between the smothering devotion of the Irish boyband model, and the slick looks and top-dollar sounds of the American one, a glut of likely British lads struggled for an angle.… The New Adventures of Tarkus 24 Jul 2002 Tarkus vs The Strokes The Friday Fun Canon Discussion And Monster Poll 12 Mar 2010 People in the Popular comments boxes are talking about “the canon”. I’m always quite curious as to which bits of the canon have ‘taken’ with a broadly pop-positive audience such as we have here. So here’s a poll, very easy to fill in, just say which of the Top 50 albums OF ALL TIME EVER […] The Music And Football Player Exchange, Notting Hill 23 Aug 2005 One of the happy upshots of the Bosman Ruling which we have been living with for almost ten years, is the effect it has on players prices near the end of their contract. Take Clinton Morrison (Birmingham wish someone would) the Republic of Ireland striker. Bought for a club record of £4.25 million three years […] THE BEATLES – “Eleanor Rigby”/”Yellow Submarine” 30 Dec 2005 #222, 20th August 1966 DIGRESSION: For Christmas I got Never Had It So Good, the first part of Dominic Sandbrook’s huge new history of Britain in the sixties. Here’s what he says about the project: “This book seeks to rescue ‘from the enormous condescencion of prosperity’…the lives of the kind of people who spent the […]	cc/2022-05/en_middle_0078.json.gz/line54
__label__wiki	0.606473	0.606473	Field Day Features State's "Big Three" The information presented on this page was originally released on August 15, 1997. It may not be outdated, but please search our site for more current information. If you plan to quote or reference this information in a publication, please check with the Extension specialist or author before proceeding. Agriculture, Crops, Corn, Cotton, Soybeans MISSISSIPPI STATE -- The harvest season is approaching for Mississippi's "big three" row crops, and it's been a difficult year for some producers. "There's a lot of variation in this year's soybean crop," said extension soybean specialist Alan Blaine. "Depending on who you talk to, it's either one of the best ever or one of the worst. On average, the 1997 soybean crop in Mississippi is a good one." The U.S. Department of Agriculture's estimate for the state's soybean crop is about 55 million bushels, up from more than 54 million harvested last year. Blaine also explained that most of the problems with this year's crop have been the result of some producers shifting form cotton to soybeans. "Many of the problems we've seen with soybeans this season have been on some of our best soils, in fields that were previously in cotton production," he said. "In many cases, the problems have been the result of low organic matter in the soil and other factors related to planting the same crop year after year. As crop rotation increases, so will yields." Blaine said the two most important factors in soybean production are planting date and variety selection. Mississippi growers planted 980,000 acres to cotton this year. Extension cotton specialist Will McCarty explained that 1997 is just the third time Mississippi's cotton plantings have dropped below 1 million acres since record keeping began in 1866. "With the acreage we started with and the losses to poor weather conditions early in the season, we will be luck to harvest 930,000 acres of cotton in Mississippi this year," he said. "The current outlook is for plantings to remain about flat next season before climbing back above 1 million acres for the 1999 season." Mississippi producers expect to harvest about 450,000 acres of corn this year, said extension corn specialist Erick Larson. There were 605,000 acres harvested in the state last year. "Statewide average yields are expected to be about 10 to 15 percent below last year's 102 bushels an acre," he said. "Corn acreage dropped this year because of poor weather conditions and good soybean prices during the planting season. "The cool, wet period during May and June stunted the growth of corn in the northern areas of the state and resulted in a poor root system to support plants," Larson said. "An additional problem for this year's corn crop was an outbreak of common rust, a plant disease that hit the crop just before pollination." Blaine, McCarty and Larson made their comments at the Aug. 12 Row Crops Field Day at the Brown Loam Experiment Station near Raymond. Producers from throughout central and south Mississippi were on hand for the event. Dr. Darrin Dodds Cotton Agronomics Dr. Jon Trenton Irby Associate Extension Professor Dr. Erick J. Larson Associate Agronomist/Specialist - Corn, Grain Sorghum and Small Grains Dr. Brian K. Pieralisi MSU student wins communication award Mississippi farmers, beekeepers work together to protect bees Bee health complexity requires scientific solutions 3D printer enhances VSC technology, abilities MSU scientists study tie between insecticides and bee health 3-Stall "L" Shaped Milking Barn (similar to 5875-A) Milking Plant Goat Milking Barn Screen Chamber Artificial Breeding Stall MBCIA Newsletter Extending the Grazing Season: Stockpiled Tall Fescue Why measure yield? http://extension.msstate.edu/news/feature-story/1997/field-day-features-states-big-three	cc/2022-05/en_middle_0078.json.gz/line56
__label__cc	0.649256	0.350744	Need to Resize Images in Various Ways? Give Preview a Try by go2g2 \| Nov 24, 2021 \| Apple Even those of us who don’t work with graphics professionally often find ourselves needing to resize images. Perhaps you have a large square headshot, but the site to which you’re uploading requires it to be exactly 100 by 100 pixels. Or maybe you have an iPhone 13 Pro... Live Text Digitizes Text in Photos in iOS 15, iPadOS 15, and macOS 12 Monterey The most magical feature of Apple’s latest crop of operating systems—iOS 15, iPadOS 15, and macOS 12 Monterey—may be Live Text. You’re probably familiar with the concept of optical character recognition (OCR), which turns all the text on a scanned page into normal... Avoid Unusual Top-Level Domains in Custom Domain Names Remember the heady dotcom days, when businesses were desperate to get a short, memorable, easily typed .com domain? It quickly became difficult to get what you wanted—so much so that deep-pocketed companies paid exorbitant sums for just the right domain. Before we go... Safari 15.1 Reverses Course, Reverts to Old Tab Interface With the betas of Safari 15 on the Mac and iPad, Apple experimented with a variety of interface tweaks related to tabs. By the time Safari 15 shipped, however, Apple had pulled back on the more radical changes from the betas, offering the new Compact Tab Bar layout... Apple Provides Temporary iCloud Backup Space for New Device Transfers When you move from an old iPhone or iPad to a new one, the easiest approach is often the Quick Start device-to-device transfer. But if that doesn’t work, or if you have to give up one device before receiving the other, iCloud Backup is a fine alternative. Fine, that...	cc/2022-05/en_middle_0078.json.gz/line68
__label__cc	0.524572	0.475428	Home About us Objectives Management Committee Institutional Members Chapters Student Chapters Contact us ISTE kerala section is constructing a building at Thrissur Click here to became a member of Indian Society for Technical Education The latest news & events, Programmes conducted by ISTE Kerala Section ISTE Newsletter - July 2021 (Special Issue) The Indian Society for Technical Education is a national, professional, non-profit making Society registered under the Societies Registration Act of 1860. First started in 1941 as the Association of Principals of Technical Institutions (APTI), it was converted into "Indian Society for Technical Education" in 1968 with a view to enlarge its activities to advance the cause of technological education.The major objective of the ISTE is to assist and contribute in the production and development of top quality professional engineers and technicians needed by the industries and other organisations. Being the only national organisation of educators in the field of Engineering and Technology, ISTE effectively contributes in various missions of the Union Government. The Ministry of Human Resource Development, CTE/DST/MIT/State Govts. are well associated with the ISTE for programmes relating to technical education. The headquarters of ISTE is at New Delhi and has sections in majority of the states and chapters in Engineering Colleges and Polytechnic colleges of the country. From the Chairman's desk Welcome to the website of ISTE Kerala Section. The main goal of ISTE is to serve as a common agency for stimulating, guiding and empowering its members to own the responsibilities as facilitators of technical education for the service of mankind and the advancement of general welfare. Suggested activities for the Chapters Annual State Conventions Annual Student Conventions Section Activities ISTE award winners ISTE News Letter You are visitor # Home \| About us \| Registraion \| Objectives \| Committees \| Announcements \| Photo Gallery \| Contact us Developed by: Winz Solutions © 2009. ISTE Kerala Section. All Rights Reserved	cc/2022-05/en_middle_0078.json.gz/line75
__label__wiki	0.821813	0.821813	Can Amazon deliver in its second biggest market A driver shortage could threaten to inflict higher costs and logistical challenges on Amazon in Germany, where subcontracted drivers complain of long hours and low pay. As Francis Maguire reports, Amazon says there isn't a problem. Rupert Murdoch's son James reveals he does not watch his Fox News or Succession. The 46-year-old son of Rupert Murdoch told the Vanity Fair Summit in California yesterday that he has not seen Succession, the comedy-drama loosely based on his family's media empire. Facebook Lays On the Charm for Its Libra Cryptocurrency Plan. Executives fanned out in Washington to court lawmakers and regulators. Mark Zuckerberg is expected to testify about Libra this week before the House. A Romantic Comedy So Dark It Makes You Cry. The narrator of Lara Vapnyars Divide Me by Zero uses her dying mothers unfinished math project to cope with two lovers, a husband and a stalled novel. Kourtney Kardashian cuts a cool look in leather as she leaves her grandmother Mary Jo's house in LA. She and little sister Kim took to Instagram Sunday as they hit the road back to Los Angeles from Palm Springs, following Kim's birthday celebrations. The party came with Skims goody bags for guests. California 'veered' out of its lane in climate pact with Quebec U.S. lawsuit. The United States on Wednesday sued California for entering a climate agreement with Canada's Quebec province, saying the state had no right to conduct foreign policy, in the latest feud between the Trump administration and the state. Porn star tells how she abandoned her Mormon faith to work in adult film business. Addie Adams, 30, joined the church when she was 17 after growing up in a religious household and spent nine years observing its ruled until moving to Los Angeles to try to become an actress. U.S.C. and the Art of Skating on Thin Ice. Coach Clay Helton is under immense pressure to turn things around for the Trojans. If he cant, it might not be just him on the chopping block. Brexit has fueled a rise in discrimination and anxiety among immigrants, study finds. Researchers from University College London looked at 300 migrants living in Britain between February and October 2017 - seven months after the referendum. The World Can Make More Water From the Sea, but at What Cost? As more places face a scarcity of fresh water, desalination is seen as a possible answer. But energy and financial requirements limit how widely it can be used. Patrick Mahomes Knocked Out of Game by a Knee Injury. The Kansas City Chiefs quarterback, who had been battling an ankle injury for weeks, hurt his knee on a sneak. Searchers find more bodies from AirAsia plane crash. Search teams bring in more bodies from the AirAsia crash to a military base in Indonesia. Rough Cut (no reporter narration). Amazon launches home delivery service that will save Aussies 10 per cent on their grocery shop. Amazon Australia has stepped up its competition with Coles and Woolworths by offering customers massive savings on home-delivered groceries. Preserving Macao's bamboo tradition through sculptural works. Many of Asia's biggest cities owe their skylines to long bamboo poles that allow construction workers to climb to great heights. Two-Thirds of College Students Take On Debt, but Amount Is Rising More Slowly. A new report found that borrowers owed close to $30,000. One factor helping the picture State spending on public colleges is recovering from the recession. Why does art matter? Banksy asks, offering originals for the right answer. British street artist Banksy is selling a Union Jack stab vest, riot helmet 'disco balls' and a 'designer handbag' made from a brick to randomly selected buyers who can answer the question "Why does art matter?". Identical twin nurses in Georgia delivered identical twin baby girls. Identical twins Tori Howard and Tara Drinkard, were born at an Athens, Georgia, hospital 26 years before the pair of sisters, now nurses, helped deliver identical twins Addison and Emma Williams. Zantac Recall Widens as Sanofi Pulls Its Drug Over Carcinogen Fears. The companys announcement follows decisions by Walgreens, CVS and others to remove the drug from their shelves and after other manufacturers recalled their products. YouTuber Trisha Paytas tearfully opens up about feeling uncomfortable in her female body. Trisha, 31, discussed her gender identity on Wednesday's episode of The Doctors after facing backlash for coming out as transgender while still identifying with her 'natural-born gender.'. Benchmark's Bill Gurley on Opportunities for venture capital. What are the trends shaping VC investment right now. Real Madrid 'targeting Unai Simon to replace Thibaut Courtois'. The Belgian's form has again come under scrutiny this season and he has not been a hit with Madrid fans since his move from Chelsea in the summer of 2018. Shopkeepers were strip-searched in police operation at Splendour in the Grass Festival. Shopkeepers returning from their lunch breaks at the 2018 Splendour in the Grass festival in New South Wales were subjected to 'military-style' strip searches. A Designers Williamsburg Apartment Bursting With Curios. Over 15 years, Sean McNanney has transformed his small railroad apartment in Brooklyn into a life-size mood board.	cc/2022-05/en_middle_0078.json.gz/line79
__label__wiki	0.68127	0.68127	[Paleopsych] Telegraph: (Pamuk) The pleasure of ruins Premise Checker checker at panix.com Previous message: [Paleopsych] Slate: Henry Blodget: The Empty Village Next message: [Paleopsych] SF Chronicle: Decrying the West's sins of secularism The pleasure of ruins http://www.arts.telegraph.co.uk/arts/main.jhtml?xml=/arts/2005/04/10/bopam10.xml&sSheet=/arts/2005/04/10/botop.html (Filed: 13/04/2005) [Noel Malcolm's review appended. I read Pamuk's novel, Snow, which should get him the Nobel Prize. It is a beautiful tale of a Turkish exile returning from Germany, ostensbily to cover the story of teenage girls committing suicide, but also to find his lost love. There's a conflict within the hero between his secular life and his attraction, nevertheless, to a rigorous form of Islam.] David Flusfeder reviews Istanbul: Memories of a City by Orhan Pamuk Europe has its share of melancholy cities: the citizens of Lisbon take each destructive fire as fate's latest grim joke; Warsaw has been regularly ripped apart by foreign invaders; and it's hard to be cheerful in Trieste or, indeed, Cardiff. But the Istanbullu novelist Orhan Pamuk makes a persuasive, if repetitive, case for his city to be ranked as the most melancholy of all. The Turkish word for melancholy is hüzün; in Pamuk's view, the city is soaked with the stuff, and so are its writers: "For the poet, hüzün is the smoky window between him and the world." Istanbul is a black and white city, Pamuk says, and in this combination of memoir and sad urban love letter the pages are illustrated with dozens of rather beautiful black and white photographs, whose romantic purpose is to allow the foreign reader to experience the same pangs as the city's inhabitants. In the ruins of Ottoman greatness, there now stands "a pale, poor, second-class imitation of a Western city", where only the mosques and the packs of wild dogs survive from the city visited by rapt or disgusted Orientalists a century and a half ago. Describing cities and city life is one of the things that literature does supremely well, but up until the 20th century all the literature inspired by Istanbul was written by Westerners, usually French visitors in pursuit of the exotic. The influence of Verlaine, Mallarmé, Valéry and Gide has been disproportionately large, but it was Gérard de Nerval and Théophile Gautier who gave Istanbullus their images of the city- "a place where, for the past 150 years, no one has been able to feel completely at home". "To be caught up in the beauties of the city and the Bosphorus is to be reminded of the difference between one's own wretched life and the happy triumphs of the past," writes Pamuk. Of course, the past was never as happy as all that, and the present hasn't always been so bad either, especially if, like Pamuk, you come from a privileged background. With the help of 20th-century Turkish novelists, poets and journalists, Pamuk does a good job picking at lines of received wisdom. It's a difficult task, which requires perhaps too many expository lessons in culture and history along the way, and isn't helped by Pamuk's essayistic technique, which perversely chooses to move from the general to the particular. ("Allow me to illustrate this with a story about Flaubert's penis," is one of the happier versions of this conclusion-to-evidence device.) For the novelist Tapinar, the poor neighbourhoods of Istanbul were symbolic of Turkey's own impoverishment in the modern world. Pamuk tells us this first, rather stealing the thunder of "Turkey's greatest 20th-century novelist", so, when we read Tapinar's words making the same observation, the argument has the diminished power of the already-read. There is plenty, however, to entertain and interest. The story of Flaubert's penis is a good one, with its components of syphilis, hair-loss, mother-love, orientalism and literary history. The account of the obsessive - and failed - encyclopedist Koçu is fascinating: a life devoted to building literary curiosity chests of city anecdote and homoerotic mutilation fantasy. But the book comes alive in the chapter on first love, when it casts off its didactic purpose to become pure memoir. The overall effect of Istanbul is like being in the melancholy company of a learned, egotistical uncle, who takes you on a slow tour of his photo albums in twilight. This uncle has perfect recall for details, but his memory is almost entirely visual - Pamuk's highest adjective for other writers is "painterly". As we are taken through the sights of ruins, as changes in the light are described to us, the other senses get hungrier. We become pathetically grateful when we are allowed any food, such as when Pamuk mentions the taste of his grandmother's sweet tea, which she always drank with a piece of hard goat's cheese in her mouth. As with any writer's memoir of his early years, the central story here is the making of the writer, the significant events, both internal and external, the movements of sensibility that have sent him on this path. Fans of Pamuk's fiction will be grateful for this book; travellers familiar with Istanbul will be stimulated; those unfamiliar with either may well be wearied. Istanbul: Memories of a City 348pp, Faber & Faber, £16.99 Telegraph \| Arts \| A boyhood on the Bosphorus http://www.arts.telegraph.co.uk/arts/main.jhtml;sessionid=CYLJ1ZEN15XQDQFIQMGCM5OAVCBQUJVC?xml=/arts/2005/04/10/bopam210.xml A boyhood on the Bosphorus Noel Malcolm reviews Istanbul: Memories of a City by Orhan Pamuk "Turkey Welcomes You!" proclaims the website of the Turkish Ministry of Culture and Tourism. "It is Istanbul's endless variety that fascinates visitors. The museums, churches, palaces, grand mosques, bazaars and sights of natural beauty seem innumerable. You can see why Istanbul is truly one of the most glorious cities in the world." And indeed you can see why: the web page is illustrated with dazzling photographs of palaces and beauty-spots, all of them drenched in golden sunshine. None of which, of course, is untrue; the photos have not been faked. But tourist-brochure images seldom convey the atmosphere of a city, and can give little idea of the texture of ordinary life. And if that is the case with cities that are dominated by their tourist industries (Venice or Florence, for example), how much truer it must be of a huge metropolis where tourism barely scratches the surface. The prize-winning novelist Orhan Pamuk was born in Istanbul 53 years ago; with the exception of a brief stint in New York he has never lived away from the city, and today he still lives on the top floor of the building that was his childhood home. He is a passionately loyal Istanbullu (the suffix "-lu" or "-li" is like the "-er" in "Londoner"), and is never happier than when poring over old photographs of the city or reading the faded cuttings of local newspapers. In his new book - part childhood memoir, part extended essay on Istanbul life - he describes, with a marvellously painterly eye for detail, what it is that he loves so much about this city. This is not the sort of detail, however, that the Ministry of Culture and Tourism would have in mind. "I am speaking", he writes, "of the old Bosphorus ferries moored to deserted stations in the middle of winter; of the tens of thousands of identical apartment-house entrances, their façades discoloured by dirt, rust, soot and dust; of the broken seesaws in empty parks; of ships' horns booming through the fog; of the dervish lodges that have crumbled; of the seagulls perched on rusty barges caked with moss and mussels, unflinching under the pelting rain; of the little children in the streets who try to sell the same packet of tissues to every passer-by; of the fruits and vegetables, garbage and plastic bags and wastepaper, empty sacks, boxes and chests strewn across abandoned street markets on a winter evening..." That is just an extract from a listing that meanders across six pages. Each detail on its own is humdrum and unexceptional, but the cumulative effect is one of lyrical intensity, the performance of a set of virtuoso variations on the themes of cold, decay, neglect, disappearance and abandonment. All these details are, he explains, things that give rise to hüzün - an untranslatable word for a collective feeling of melancholy and nostalgia. Hasty or hostile readers (including, no doubt, the men from the Ministry) might prefer a less untranslatable term for Pamuk's frame of mind: nostalgie de la boue, a perverse wallowing in dirt. And if all he had produced had been a hymn of praise to decrepitude, they might have a point. But this book does much, much more than that. It sets his fascination with the tumbledown world of backstreet Istanbul in two contexts: that of his own discovery of the city as a child, and that of the cultural history of postOttoman Turkey. There was nothing decrepit about Orhan Pamuk's own childhood home - at least, not in physical terms. His grandfather had made a fortune in business, and although this was gradually frittered away by Orhan's father and uncles, there was plenty of it to fritter. Orhan was brought up in the "Pamuk Apartments", a five-storey block built and owned by the family: all the other inhabitants were uncles and cousins, plus an assortment of maids, cooks and caretakers. From this world of wellfurnished rooms - glass-fronted bookcases, grand pianos laden with silver-framed photographs, and so on - little Orhan would venture forth with his mother to the sweet shop, the bread roll-seller, or the toy shop; sometimes a boatman would row them up the Bosphorus, or sometimes they would ride on the tram. Everything fascinated the boy, whose visual sense was stimulated as much by crumbling stone and decaying wooden buildings as by the coloured lightbulbs on the minarets or the chocolates in silver foil. In his teens, while attending an expensive private school, he thought of becoming a painter, and spent long hours walking these streets, studying the play of light and shade and the effect of those sudden glimpses of the Bosphorus through the gaps between the buildings. His schoolfriends, meanwhile (mostly the sons of the nouveaux riches), spent their time driving their fathers' Mercedes to cafés where they could drink Scotch whisky and listen to American music. Their aping of a foreign world drew him, by contrast, to cherish more strongly those aspects of Istanbul that they were most keen to reject. A similar dynamic, though a subtler one, was at work in his relations with his own family. Unlike the coarser nouveaux riches, they valued culture and education; but having lost touch with their own Ottoman past, they could think of no content for that culture except a hand-me-down West European one. In this, Pamuk thinks, they were typical of a generation which, even though it benefited in many ways from Atatürk's Westernising campaign, was nevertheless culturally and spiritually stultified by it. Some people might react to such a situation by longing for a neo-Ottoman cultural revival; but that is not a real option, given the degree to which all modern Turks are now separated from their past. (They cannot even read anything from before the 1920s, since the old Arabic script is unintelligible to them.) Others might turn instead to some form of Islam; this is a real option for many, especially for those who have only recently moved to the big city from village life. For millions of middle-class Turks, however, this solution has no appeal whatsoever. Orhan Pamuk has taken a different path. He accepts the loss of Empire, the decay of grandeur, and the failure, in petty ways, even to imitate competently the Western practices that have become such unquestioned models. For him, this is the authentic Istanbul, and because it is authentic, it deserves to be loved and celebrated. The same is true of his family, which he loves for all its faults - the faults being, as this book delicately insinuates, the same, ultimately, as those of the city itself. This evocative book succeeds at both its tasks. It is one of the most touching childhood memoirs I have read in a very long time; and it makes me yearn - more than any glossy tourist brochure could possibly do - to be once again in Istanbul. Noel Malcolm's books include 'Bosnia: A Short History' and 'Kosovo: A Short History' (Pan)Golden days on the Golden Horn Orhan Pamuk, left, is a passionately loyal Istanbullu and a painterly chronicler of the life of the city More information about the paleopsych mailing list	cc/2022-05/en_middle_0078.json.gz/line85
__label__wiki	0.935891	0.935891	Top 3 Samsung CEOs to retain positions From left are Samsung Electronics mobile chief Koh Dong-jin, consumer business chief Kim Hyun-suk and semiconductor business chief Kim Ki-nam / Korea Times file By Baek Byung-yeul Three Samsung Electronics CEOs ― those in charge of semiconductors, home appliances and IT and mobile communications ― will remain in their positions despite the upcoming year-end management reshuffle expected to take place this week, sources knowledgeable about the issue said, Sunday. "Samsung will keep on its three CEOs who are responsible for its three major pillars. But the company will diversify its executives' pools by expanding the promotion of low- and medium-ranked executives for the reshuffle," one of the sources said. Samsung's business structure comprises three major units ― Device Solutions overseeing its semiconductor business, IT & Mobile Communication supervising mobile devices and Consumer Electronics for TVs and home appliance products ― and each unit has been led by one of the three CEOs ― Kim Ki-nam, Koh Dong-jin and Kim Hyun-suk, since 2018. Samsung's 2021 management reshuffle on both the C-suite and below the top brass-level is receiving growing attention as this is the first realignment of the company's organization since Vice Chairman Lee Jae-yong returned to management after being released on parole in August, seven month after being imprisoned over bribery. Upon arriving home from the United States, the Samsung chief said on Nov. 24 that "I feel heavy of heart after seeing the harsh reality of the market in person," when asked how he viewed the group's future prospects. During his around 10 days of business meetings in the U.S., Lee traveled all over the country to meet CEOs of top firms there, such as Microsoft, Google, Moderna and Verizon, and to find future growth areas for Samsung including in biotechnology, telecommunications and IT. He also finalized a $17 billion investment project in Texas for establishing a new foundry factory. His remarks can be interpreted as Samsung needing to apply "something new" from inside to further widen the gap with latecomers in the rapidly changing global economic environment. Within that context, what visible changes could be made especially for its governance is another point of focus, as Samsung requested an assessment by Boston Consulting Group (BCG) regarding its compliance and human resources systems before a possible reorganization. BCG referred to cases of large overseas conglomerates overhauling their governance. Based on the consultation results, another source said Samsung is inclined to establish a new "group control tower" after it had voluntarily dismantled its previous one a few years ago. But this time, the new unit, if it actually materializes, will let new personnel recruited from outside have more authority, with existing members of the now defunct group strategy office taking supporting roles. Before its dismantlement, the group's strategy office had some 200 elite Samsung officials and functioned for nearly six decades. In 2017, however, Samsung leader Lee told lawmakers he would make direct moves to close the office after the unit came under criticism regarding the scandal that led to the impeachment of former President Park Geun-hye. A committee set up in 2020 to meet compliance with a court order is also looking into the matter to ensure legal violations do not arise. "Issues related to succession are one of the three key areas we are monitoring," a spokesperson for the committee said. "The committee's role is to ensure that ownership matters are decided within the frames of abidance by the law." In addition to the reshuffle of executives, Samsung is in the process of finalizing new human resource management systems. An official announcement of its new HR system is planned for this week. The HR system overhaul could include expanding the evaluation of employees' performance on an absolute rather than relative scale and adopting peer evaluation methods. "Samsung Electronics is trying to create a flexible and horizontal organizational culture," a Samsung official said. Baek Byung-yeul baekby@koreatimes.co.kr Samsung overhauls personnel system to nurture young leaders	cc/2022-05/en_middle_0078.json.gz/line87
__label__wiki	0.67442	0.67442	Facebook Twitter Google+ RSS Mulaaqaat with Manik Manik on Youtube Chittorgarh Film Festival manik@spicmacay.com Audio Work Apni Maati E-Magazine Sansmaran Apni Maati Magazine Baseda Ki Dairy 03 अगस्त, 2013 Home » Classical Art » Pandit Shiv Kumar Sharma » Profile of Santoor Guru Pandit Shiv Kumar Sharma Profile of Santoor Guru Pandit Shiv Kumar Sharma Santoor is a very ancient instrument of India. The original name of this instrument was Shata-tantri Veena which in Sanskrit language means a Veena of 100 Strings. Today, when we say Veena, it means a specific instrument but in ancient times Veena was a common word for different kinds of string instruments. The first string instrument was called Pinaki-Veena. The idea to create this instrument came from the Bow & Arrow when Arrow was released it created a sound out of that idea somebody created a musical instrument and named it Pinaki Veena. Pinak in Sanskrit language means the Bow and the idea to create this instrument came from the Bow & Arrow that is why it was named Pinaki Veena. In the Western Countries this instrument is called the Harp and in India we have got a miniature form of the same instrument known as “Swarmandal” which many vocalists these days use while singing. After Pinaki Veena, in Ancient India, we had different kinds of Veenas like Baan Veena, Katyayani Veena, Rudra Veena, Saraswati Veena, Tumbru Veena, & Shata-tantri Veena. In Ancient Scriptures of India there is mention of Shata tantri Veena which is known today as “Santoor”. This instrument got its present name Santoor with the Persian language influence in our Country. There are Hundred Strings in Santoor. It is a hollow box on top of which there are 25 bridges. Each bridge used to have 4 strings resting on it. To play this instrument, two wooden mallets are used. This instrument had been in use in the Valley of Kashmir for many centuries, in a typical type of Music known as “Sufiana Mausiqi” which means a music connected with Sufi philosophy. In this style mostly Santoor is used as an accompaniment with the singers and sometimes played as a solo instrument also. In 1940s & 50s, the best known Sufiana Musicians in Kashmir Valley were Mohamed Abdullah Tibbat Baqaal and Mohamed Qaleen Baaf. Till then Santoor had never been used in Indian Classical Music. Actually outside the Valley of Kashmir nobody had seen this instrument or heard the name Santoor. The Journey of Santoor changed in early 1950’s when Pt. Umadutt Sharma, Father of Shivkumar Sharma, who was a very versatile Musician, a performing Vocalist, and Dilruba player but equally well versed in playing Tabla & Harmonium, saw this Instrument in Kashmir and thought of introducing Indian Classical Music on Santoor. He had an intensive training of Music under Pt. Bade Ramdasji a legendary Vocalist of Benaras Gharana. In early 50’s Pt. Umadutt Sharma was Music incharge of Radio Srinagar for a few years. During that period he did an extensive research on Santoor and started teaching his Son, Shivkumar Sharma the intricacies of Santoor. Shivkumar Sharma was initiated into Music at the age of 5 (five) as a Vocalist & Tabla player. He had started performing at a very young age as a Tabla player from Radio Jammu and Srinagar. It was an intriguing choice for Shivkumar Sharma to take up Santoor as his main instrument which had never been used in Indian Classical Music before that but as it was the will and direction of his Guru & Father, he started learning Santoor. Later on Shivkumar Sharma had to carry on his experiments with Santoor for many years which improved in Tonal quality, in playing technique, in sitting posture of the instrument, in repertoire of music and emotional and spiritual expression of this instrument which has given Santoor its own distinct character. One interesting feature about Santoor is that similar kind of instruments are found in different parts of the world, with different names. In China its called Yang Quin, in Central Asian Countries Cimbale, in Iran & Iraq Santoor, in Greece Santoori, in Germany Hackbret, in Hungary Cymbalom and many European Countries and in America Hammer-Dulcimer. Noteworthy thing is only in the Valley of Kashmir we have got Hundred String Santoor whereas in all above mentioned forms the instrument has got either less or more than 100 strings. That proves a point it was known as Shata-Tantri Veena in Ancient times and that’s why still in the Valley of Kashmir Santoor has got Hundred strings and no where else. Some people claim that Santoor originated in Iran but according to Indian Musicologists and Ancient Sanskrit scriptures Santoor (Shata-tantri Veena) is an Indian instrument. There is also another theory that gypsies travelled from India to different other countries in Europe etc. probably they carried this instrument from India where it got different names and shapes in different parts of the World. In Hungary for example gypsy music is played on Cymbalom. In fact Santoor is the predecessor of Piano because it is based on the same system. There are strings inside Piano which are struck by small hammers when we press the keys of Piano. The modified Santoor which Shivkumar Sharma plays now has got 31 bridges, total number of strings 91. It has got a range of 3 Octaves and chromatic tuning. In Kashmir Santoor is kept on a wooden stand in front of the Musician while playing. Shivkumar Sharma changed that posture and started keeping it on the lap to cut the extra unrequired resonance which resulted in getting a very clear tone even while playing very fast passages like taan and Jhala. Although this is a difficult posture to maintain and requires some training of Yoga to maintain the spine in an erect form for longer duration of performance otherwise it can be difficult to sit in this posture. The height of the Musician also counts to maintain this posture. The mallets are held inbetween Index and Middle finger and the thumb. This is again very important part of holding the Mallets which is used in a very subtle form to create the meend (the technical term for playing unbroken notes). It’s a very important factor of playing this instrument, the mallet held in any other position will not produce this kind of tonal quality. There was a time when Santoor was manufactured only in Kashmir but now there are Santoor makers in Mumbai, Delhi, Kolkata, Punjab and Varanasi who are making Santoors according to the modifications carried out by Shivkumar Sharma which has become a standardized form of this instrument. All his disciples and most of the other Santoor players who may not be his direct disciples around the World are following this system of Santoor playing. As everybody knows in the field of music technicalities of playing of an instrument can only be learnt directly from the Guru otherwise picking up the technique just by listening to the records or concerts or even videos can go wrong. Shivkumar Sharma has always encouraged serious students to come and learn from him directly which he has been doing for the last 40 years. Source: http://www.santoor.com इसे ईमेल करेंइसे ब्लॉग करें! 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What About Gotipua Dancer Gotipua is a traditional dance form in the state of Orissa, India, and the precursor of Odissi classical dance.[1] It has been performed in ... 1st Film Screening & Panel Discussions-2014 in Chittorgarh माणिक अब तक यात्रा , मधुमती , कृति ओर , परिकथा, वंचित जनता, कौशिकी, संवदीया , उम्मीद और पत्रिका सहित विधान केसरी ... Copyright © 2012 माणिकनामा(Manik Ji) All Right Reserved Designed by ivythemes • MKR Site	cc/2022-05/en_middle_0078.json.gz/line90
__label__cc	0.736301	0.263699	Pants and sweatshirts for childrens Posted by Kathie, on March 01,2019 1588 Bogatis ж enamelled jacket with a matching tactile panty sweatshirt. The magazine “Baby Broom” No. 4/2018 Size of the software of 6 months (9 months – 1–2 years) 4 years Oblum of a thunder: 54 (58–62–64) 67 cm Duration: 28 (30–33–37) 42 cm Long handle: 15 (18–21–24 ) 27 cm Bpyuchki 6 mecyatsev (9/12 mecyatsev goda-2) 4 goda Obhvat bedep: 53 (55-58) 61 cm Dlina shtaniny: 15 (18-21) 25 cm ΒAΜ ΠOTRΕBUΕTSYA Πpyazha Sandnes Garn Babyull Lanett (100% mepinocovoy shepty, 175 m / 50 g) - for a jacket: 2 (3–3–4) 4 bales of the orange (No. 3427), 1 rolls for each size of the white-white color (No. 1012); for trousers: 3 (3–4) 5 bales of opaque (No. 3427); circles 2, 2.5 and 3; stockings number 2, 2.5 and 3; makers for styling the hinge; 6 (6–7–7) 7 fearsomers; electrical tape width 2 cm. PATTERNS AND Wrong, alternately 1 person, 1 externally, strengthened; in dormant ranges, all knitted in the pattern. Β circle knits alternately knit 1 person, 1 from the outside. PERSONAL FACILITIES Persons in order - faces in the face, externals in the range - faces in the fold; in the outer rows, all of them are knit in the face. IZAΗOCHENAYA LIKE THE PERSONS OF THE PERSONS - THE EXTERNAL POLITICS, THE EXTERNAL SERIES - THE LITERAL POLICE. SHOCK PATTERN Washable hinges вo all around the knit face. LETTER LIABILITY 31 (27) n. = 10 cm, related to the person number in 2.8 (3). ΒYΠOLOLS Ε WORK OF ΚOFTA SΠIA AND Π SANDS With a round thread on knitting needles No. 2.5, set 153 (163–173–179) 187 p. And knit in rows in straight and reverse direction. Link 3 (3–4–4) 4 cm by rubber, starting in 1 cc. and 1 out. and the 1st primer on the 1st floor their banana The line from both sides of the 6 p. To lay off for the strips of sheaths that are knitted later. Click on circle buttons № 3 and add a new 4 points at the end of the series (= heals for cutting, do not turn into a pattern and are not taken into account when specifying the number of colors). Reciprocate 2 makers from each side, at 34 (37–39–41) 43 points for each shelf and 73 (77–83– 85) 89 points for the backrest, and then knit in circles. Bind on DIAGRAM A, starting with the above for selected dimension. Having connected one another with a plan, let's follow the “Soks” motif; after 13 (15–18–22) 27 cm from the initial series, knit on the basis of the scheme and on the basis of the scheme C. Via 24 (26–28–32) 27 cm from the starting series for the heart rate of 16, 16 16 16 n. before closing and knitting in a row with straight lines. In this case, in order to curtail a hormone in the beginning of each row, close each side of 0 (0–0– 0) 1 x 3 p., 2 (3–3–3) 0 x 2 p. And 3 (2–2–2) 2 x 1 p. Cherez 28 (30–33–37) 42 cm from the starting row of the remaining 117 (123–131–135) 139 p. RUΚAΒA With a green thread on the stocking needles No. 2.5, set 34 (36–36–38) 40 paragraphs and tie 3 (3–4–4) 4 cm back and forth. Click on the number 3 lips and link 1 to the circle. person's face, when this is the case, add a pet so that it is on a steel of 42 (44–44– 46) 48 p. Mark the first and last petrols of the last p. Bind on Schedule A, count the chains from the center of the handset to determine the starting point of the motive. With one side of the carriage, add 1 p. To bind the “Sohka” line by twisting 2 (2–1.5–1.5) 1.5 cm, put it on the back of the harness; 76 p. Next knit without prises, through 12 (15–18–21) 24 cm from the starting row (or 3 cm from the end of the hand) knit according to the diagram “. Turn on the work of an external handset and connect 5 facets to the right face (podgib). Close all hurts. So also connect the second hand. WITH A SEWING MACHINE Place the two seams on each side to cut from each side of the center and cut them apart. Measure the width of the upper side of the arm and mark the depth of the armor from both sides of the backrest shelf. Place both sides of the two sides of the two seams at the desired depth and cut between them. Embed stitches and sew the stitches. Remove the curb on the side of the seat and push it without tightening it. Lnke the To impose these 5 p. Of external helium, a 6 p. Of the strip of the shelf - rubber. When the length of the strip on the stretched video card is matched with the high shelf, close the loop of the stripping strip and pull off the 6 sect of the strip of the shutter. Also, connect the second strip of the strip, but execute it with a regular interface 6 (6–7–7) 7 retreats for fearsomers: the upper half of the mouth of the golovina (tied by the head of the head of the prostromes, the head of the person, the head of the person, the head of the person, the head of the person, the head of the progeny, the head of the head of the golovina (the head of the head of the head of the head of the golovina (the head of the head of the progeny of the head of the golovina (the head of the head of the head of the golovina), the head of the head of the head of the golovina (the head of the head of the head of the head of the golovina, the head of the head of the head of the golovina (the head of the head of the head of the head of the golovina) (the head of the head of the head of the gland of the gland of the head of the golovina (in the head of the head); Borrowing the film, connected with the back, to the sheath, mark the end of the strips with the broken side and hang on from the wrong side. For the golovina film, make the detached polygraphs of the biblical fray of the sniffers of the order of the biblies of the standers of the order of the lawyers of 2.5 P.); the number of the number must be 2 + 1. Connect 3 with a rubber directly, like for the backrest / shelf, complete with a perfect opening for the psychic bug, and cover all of it with a curtain. Пpishit bogeys. BRUCHΒΗI ΒΗIΜAΗIΕ! Bryuchki knit from podya. ΒΕ AREA PART к a circle buttons number 2 set 138 (142–148) 154 p. And knit in curved rows. Link 2 cm of face heel (podgib) and 1 krug.p. individuals (in order to support the last, indicate how the initial series). Associate another 2 cm with the face of the head and in the last series equip 20 (24–26) 28 p. (= 158 (166–174) 182 p.). Jump on the number 2 buttons and pin 2 cars on the middle of the back and front parts (located between the 78 (82-86) and 90 points). For the rest of the year Having completed 5 (5–6) 6 varieties of work, tie each of them to each other along with the following patches in order to avoid repetition. Next, knit on all the faces of the person with the eye of the circle in circles and at both sides from the middle of the middle of the back part of each 3 cm to add 3 x 1 n. (= 164 (172. 2 2). After 15 (16–18) 19 cm of the initial range, measuring in the first part, in each 2nd circle .p. From both sides of the front and back part, add 10 x 1 p. (= 204 (212–220) 228 p.). Separate the work in the middle of the front and rear parts and knit both of the pants separately. STAFFAAA to bind to 102 (106–110) 114 n. In circular rows. Recruit makers in the middle of 2 pts (in the area of the competition) and from both sides from the carriage to reduce to 1 p. To the following pattern: connect in front of 2 mars. cross-sectioned after 2 n. Revise each 2nd Circle.p. another 5 times, then in each 6th circle. p. esche 3 times (= 86 (90–94) 98 p.). After 13 (16–19) 23 cm from the partitioning, move the knuckle to No. 2 knitting needles and tie 1 circle of pp, fastened by horny persons. (= 43 (45–47) 49 p.). Link 2 cm of face heading, 1 circle.p. externally and 2 more persons face glare (podgib). Closing is not hindering, not squeezing. So do tie the second leg. ALLOW ALL THE FOOTBALLS TO THE EXTERNAL SIDE AND SUPPORT, NOT STRETCHING, OPENING UNDER THE OPENING; go back to the opening of an electric ribbon and sew it ends. Crochet Baby Cap Baby Jumper Free Pattern Knitting Baby Vest Free Pattern BABY OVERALLS FREE PATTERN BABY SOCKS TINY Knit Hat and Glove for Baby Colorful Baby Sweater Crochet Baby Vest Pink	cc/2022-05/en_middle_0078.json.gz/line95
__label__wiki	0.834505	0.834505	How to Create a Digital TV Network Tj Walker You can create and produce your own TV network on YouTube This course is for business people and experts who want to share their expertise with the world. You no longer have to wait for the occasional call from a newspaper reporter, talk radio host or TV producer. You can now broadcast your news, opinions, and insights in a TV/Video format every single day. The technology is easy, but the step by step plan to start can be hard for most people. This course will walk you through everything you need to know so that you can be up and broadcasting very quickly. Pre-requisites for the course: What is the target audience? Publicity Hounds Candidates for Public Office SECTION 1: Your TV New Network How to Create a Digital TV Network Overview What is Your Editorial Focus? How to Actually Start Your Network Determining Your Style Options Your Technology Needs Blunders to Avoid Promoting Your Channel Adding Graphics Determining Your Business Model Bonus 1 Final Tips Bonus 2 More Tips on Building Your Studio Over 10 lectures and 1 hour of content! Start your own professional TV newscast on YouTube Know how to look comfortable on camera Determine an editorial mix and calendar Figure out monetization strategies Dix Hills , United States TJ Walker is the founder of Media Training Worldwide and has been conducting media trainingworkshops and seminars since 1984. Walker has trained Presidents of countries, Prime Ministers, Nobel Peace Prize winners, Super Bowl winners, U.S. Senators, Miss Universes and Members of Parliament. His book, "Secret to Foolproof Presentations" was a USA Today #1 Bestseller, as well as a Wall StreetJournal, and Business Week Bestseller. Walker is a also a regular contributor to Forbes and the ReutersInsider Network and has written for the Huffington Post. A frequent network news communicationsanalyst, Walker has made more than 1000 network TV and radio appearances on CBS, ABC, Fox NewsChannel, MSNBC, CNN, Bloomberg TV, Al Jazeera, NBC, CCTV, Fox Business, Russia Today, HLN, TrueTV,Comedy Central, Sirius and NPR. In 2009, Walker entered the Guinness Book Of World Records for most talk show appearances ever in a 24 hour period. Walker is also the author of "Media Training A-Z" and "Media Training Success." Walker is also theproducer/host of The TJ Walker News and Comment Channel on YouTube which has thousands ofsubscribers and millions of views. Walker was a merit scholar at Duke University where he graduated magna cum laude. He has lectured or conducted trainings at Yale University, Columbia University and Princeton University. Schedule & Syllabus Please wait while we are fetching data... Oops! Our servers are experiencing minor hiccups. Please try again. No course content has been added Learn on the go. Download for	cc/2022-05/en_middle_0078.json.gz/line100
__label__cc	0.707209	0.292791	Weaving the Tapestry of Life: The United Nations and Global Governmentality Mendly, Dorottya (2020) Weaving the Tapestry of Life: The United Nations and Global Governmentality. PhD thesis, Budapesti Corvinus Egyetem, Nemzetközi Kapcsolatok Doktori Iskola. DOI 10.14267/phd.2020011 PDF : (dissertation in English) PDF : (rövid összefoglaló magyar nyelven) Weaving the Tapestry of Life. The United Nations and Global Governmentality My doctoral research evolves around the question how the Secretaries-General have been constructing the UN as a peculiar subject in world politics, and how this construction is linked to the cognitive structures in which global governance is imagined. These problems are best comprehensible in a post-structuralist framework, where structures of knowledge and discourses are typical tools for doing research. This approach has the capacity to reveal very different facets of International Relation’s general problem, often formulated as ‘what makes the world hang together’, what makes it look like someone is governing? I address similar issues, but from a definite point of view, which stands on a long and diverse traditions of scholarship when it hypothesises the UN’s role on the one hand, and structures of knowledge on the other. My point is that these cannot be treated separately if the above questions are to be answered, and, that a promising entry point is the analysis of discursive mechanisms. I assume that the discourse of world politics as global governance, structured by the dynamics of ‘modern political rationalities’, is in a complex relationship with the UN, and especially the construction of its ‘subjectivity’ since its establishment. This approach places the focus on a cognitive structure, but also stays sensitive to agency. That world politics is imagined in terms of global governance was nothing new around the end of the Cold War, but it certainly gained momentum, thanks in large part to the collective efforts put in elaborating the discourse of global governance. The creation of the UN was a significant and symbolic development, which makes it an intriguing object of research. The above elements – the discourse of global governance, the UN’s subjectivity (meaning the ‘acting Self’ constructed through discursive mechanisms) and modern political rationalities (the frames of our political imagination) – are thus argued to be entangled in a set of complex relationships, the unravelling of which is the primary goal of my project. I assume that it is the discourse of global governance which integrates the other parts under its ‘order of knowledge’, and has the capacity to embed the research question in a broader debate on the changing character of world politics. Making these linkages engendered the questions guiding this research: How has the UN’s subjectivity been formed in relation to the shifting rationality of world politics? How has the discourse of global governance organized this interplay of subjectivity and political rationalities? The empirical dataset I work on to answer these questions is one which I extracted from the Annual Reports of the Secretaries-General on the Work of the Organization. I investigate the UN’s ‘subjectivization narrative’ primarily with the tools offered by (Foucauldian) discourse analysis. I present the analysis and the results in a narrative-, and then in a discourse analytical step, and interpret my results in the framework offered global governmentality theory. The empirical chapter also presents an original interview research, which is used to describe accurately the process of producing the Annual Reports in the Secretariat on the one hand, and to confront the interviewees’ stories (who are officials of the UN Secretariat, working on the Secretary-General’s reports) with the knowledge structures they are grounded in. My conclusions outline the complex set of relationships between the UN, global governance, and how our thinking about world politics has evolved in the past decades. Szűcs Anita 10.14267/phd.2020011	cc/2022-05/en_middle_0078.json.gz/line110
__label__cc	0.632766	0.367234	Home Imperialism in the 21st Century Plundering and Profits: Moving Beyond Dependency Theory Plundering and Profits: Moving Beyond Dependency Theory ROAPE In a major critique of dependency theory, Esteban Mora continues the debate on the nature of imperialism on roape.net (and specifically the blogpost by Walter Daum). He argues that while inequalities and unevenness in the world market exists, with both strong nation-states and weaker ones, this is not a division based on countries or regions, nor geography or ethnicity, but on relations of production. We must unearth the mechanisms of mutual profiting across all regions to see a class divided world market, as part of an international system of states where every single state is an agent of financial capital. We urge our readers to follow the debate here. By Esteban Mora In the on-going debate on imperialism on roape.net, Walter Daum distorts arguments that I have made in a response to this debate. In this blogpost I am going to try to expand on the subject, and at the same time, answer Daum’s critique. First off, I did not deny in the original blogpost that there is a draining from South to North, nor that there is any draining at all between strong and weak countries. I said my view was complementary. Why complementary? Because in the possible inversion between East Asia and Triad countries, we should not expect the inversion of draining, but a mutual profiting with a relatively new positioning between strong and weak countries in the world market. So, if we understand the market only by such terms and processes of ‘draining’ where one is a strong ‘draining state’, and the other a weak dependent state, how are we going to understand this inversion of roles between countries who are both strong or becoming so, and who also drain others (and even each other, such as the automobile industry, where East Asia and the Triad both share production sites and markets with each other)? In addition, how do we avoid making the mistake of thinking the Triad is going to become a Third World dependent-republic, as a radical inversion of roles between North-South? Instead, could it be concluded that there are more universal and global mechanisms which permit a smoother transition from one position to the other, and which do not imply a simple reversal of the Triad’s hegemony, due to the fact that it now shares much of its characteristics with East Asia? Now, to the three strategies discussed by Daum: 1) There is no mention of a hegemon in any theory of imperialism by Lenin or Bukharin or anybody, nor of any ‘three worlds theory.’ Obviously, I do not reject inequalities and unevenness in the world market, nor that there are big, strong nation-states and weaker nation-states (metropolitan and peripheral, if you want), but this is not based on countries or regions, nor geography or ethnicity, but on relations of production. This implies ‘sharing’ not only mechanisms of draining, but also mechanisms of mutual profiting which forces us to go beyond chauvinism, nationalism, and regionalism, and see the world market as class divided, between an international bourgeoise and international proletariat; as an international system of states where every single state is an agent of financial capital. Or as Lenin wrote: ‘Relations of this kind have always existed between big and little states, but in the epoch of capitalist imperialism they become a general system, they form part of the sum total of “divide the world” relations and become links in the chain of operations of world finance capital’ (Lenin, Imperialism, Highest Stage, Chapter Six). 2) By ‘relative’ I do not mean the ‘rate’ only, I mean the fact that two absolute amounts of profit can be the same (as in China and the US, as I cited), or can even be bigger than the other (as in the examples Daum uses from the same report), and this does not imply the same purchasing power, the same exchange rate, nor the same control over the means of production; essentially the same amount of mass of profits in the US is not worth nor functions in the same way in East Asia, nor do the absolute amounts of profit equal the same purchasing power or relationship with constant capital, since raw materials can be cheaper, jobs low-priced, and capital goods as well, etc. So, Daum can find in East Asia a smaller mass of profit than the Triad, but this is not a measure of the rate of profit, nor a measure of the relationships between this mass and purchasing power, raw materials, capital goods, etc. It is not only a matter of the relationship with constant capital, but appropriation of value. In other words, there could be a bigger appropriation of value in Marxist terms, where there is a smaller mass of profit (the only way profit numbers between West and East can be equivalent with each other, is if any other factor of production involved – constant capital specially – is also equivalent according to the exchange rate between the two monetary systems, commonly dollars and any other currency. This is highly unlikely and forces us to be cautious on the use of absolute quantities as markers of profit or value, as Smith and Daum argue. This notion helps us to understand the working of value across different exchange rates, currencies and the world market, etc. (There is a short explanation of this process here). Using two amounts of profits plain and simple, and looking for the biggest one as a mark of profit rates or purchasing power or the relationship with constant capital, etc, is not even Ricardian economics. All the defenders of the orthodox view on economics simply show data where profits are bigger, as if the whole discussion was the matter of a single amount or a single quantity or magnitude deciding everything, when it’s a matter of a relationship. 3) I do not mean South and North countries are equivalently profitable, nor that there are no differences between small and big countries. Rather I argue that besides these differences in ‘draining’ which permit large countries to exploit small countries, there is a mechanism (a ‘neo-colonial’ and also ‘dependency-like’ mechanism) which allows for the maintenance of the international imperialist system, not a radical break or absolute heterogeneity between ‘draining and drained countries’ that both Smith expects, and Harvey claims is already occurring. I also said something else that Daum ignores: why do high-tech industries, industrial production, gross capital formation and capital goods exports all now come from East Asia and not the Triad? For this reason, we must move beyond a number or figure and ask about the relationships at the level of the world market. Are we going to reduce the whole imperialist debate to who has higher profits, and do this without understanding profits relatively but as an absolute mass? Industrial production, gross capital formation and capital goods exports were characteristics of the Triad when they were called imperialists. All twentieth century Marxism is based on this assumption. What are we to say about franchises and all sorts of export of capitals which occur right now thanks to the internationalization of the division of labour and the multinationalization of capitals? Even countries like Costa Rica, in Central America, has started to ‘drain’ other countries through franchises, and Guatemala already has its own multinational. Multinationals from the South have all been developing rapidly in the last 20 years, which ‘drain’ Triad countries. Is Costa Rica ‘imperialist’ because it drains flows of money from South America and the rest of Central America? What are we going to do with these phenomena? Do we instead need to understand every nation-state as part of imperialism, whether metropolitan or peripheral, or are we going have to keep dividing up regions (like Three Worlds Theory) and insist on outdated notions? Also what has happened to the ‘industrial countries’ and ‘agricultural countries’ divide that was so important for Bukharin and Lenin, yet which does not exist anymore? Are we going to cling to the past, or look into the rich and real phenomena occurring in the world market in front of our eyes? This is where I once again insist that instead of looking for a radical inversion of the world market where superpowers become dependent countries and vice versa, like some spectacle in science fiction, we have to start to analyze more complex processes beyond dividing the world into imperialists and non-imperialists, or into region 1 and region 2, even when they are clearly bigger than the others – this is exactly what takes place in distorted universe of Three World Theory-dependency theory, and other theories which share this outlook. Draining is more complex, to the point that it is not only the Triad which is responsible for it. Since, if ‘draining’ is the only characteristic that makes a country imperialist, then you have a methodological problem of enormous dimensions with every country from the Caribbean to the Pacific enjoying inflows of value (‘draining’, in a word). Rather there seems to be an uneven development in the market, but also a synchronicity – maybe like the one asserted by Wallerstein, which goes beyond nations and regions, while at the same time making some bigger than others. Plundering does not always involve an absolute deterioration for the smaller partner, rather a relative plundering and mutual profiting moving in multiple directions. Is this so hard to come to terms with in the actual workings of the modern world market? In this important debate on imperialism on roape.net, this is what I propose. Esteban Mora is a researcher in Communications Science at the Universidad de Costa Rica, he has written three books on capitalism and Marxism, and writes a Marxist economics blog. He has recently reviewed The History of Business in Africa by Grietjie Verhoef. Verhoef makes an important historical argument about the role and agency of African capitalists from the early colonial period. Mora argues that Verhoef forces us to rethink more orthodox accounts of the development of capitalism in Africa. Featured Photograph: Views of Vilnius, Lithuania in 2017 Combined and Uneven Development Relations of Production Three Worlds Theory Unevenness Previous articleTransition – an iconic, incendiary African magazine Next articleGhana’s War on Piracy: Copyright and Human Rights in Africa From summit to counter-summit: imperialism, Françafrique and decolonisation Structural inequalities and the political economy of citizenship	cc/2022-05/en_middle_0078.json.gz/line114
__label__cc	0.698582	0.301418	Clynxx Unveil All-in-one Groundbreaking Digital Health Solution For UK Private Clinics Launched in 2016 as an electronic private prescription service, Clynxx has been at the forefront of the digital health revolution. Now, the innovative brand is launching a complete all-in-one solution, offering digital health records, electronic private prescriptions, online booking and integrated video conferencing, alongside the ability to create invoices and order blood and diagnostic tests. Technology has transformed the world we live in, and since 2016 Clynxx has been helping transform healthcare through digital solutions. Launched by pharmacist Tuck Muswizu, Clynxx began as an electronic private prescription service, allowing prescribers to create fully regulated and compliant private electronic prescriptions that were valid both in the United Kingdom and the European Union. Since then, the forward-thinking brand partnered with several major pharmacy stakeholders in the UK, allowing their electronic private prescriptions to be accepted in the likes of Tesco, Well and Lloyds pharmacies. The system was also appraised by the National Pharmacy Association (NPA), which represents 80% of the pharmacies within the UK, recommending the service to all of its members. Clynxx was also the first company to offer automated regulatory compliant onboarding using digital biometric technology and regulatory database cross-checking. Now, Clynxx is ready to take digital healthcare to new heights with the launch of its innovative all-in-one system. These new developments have been designed to allow prescribers full access to digital health records or patients and the ability to offer electronic private prescriptions with ease. The FreeRx® software enables patients and pharmacies to quickly and efficiently retrieve electronically signed private prescriptions, removing the need for paper while maximising privacy and confidentiality. Not only will users be able to issue electronic private prescriptions, but they can now also enjoy automatic scheduling of appointments. This unique feature will let patients book appointments online, with each session automatically being added to the clinics calendar, preventing any risk of double booking. This online booking session is also available 24/7, ensuring patients are able to book their appointment at any time, meaning doctors are no longer limited to only booking patients during opening hours. The recent pandemic has seen doctors and patients having to engage and interact virtually, and the new Clynxx all-in-one solution will be providing integrated and secure video conferencing technology. This technology will allow doctors to offer remote appointments, ensuring maximum convenience and helping to increase patient satisfaction. All integrated video and telephone appointments organised through Clynxx will also be automatically transcribed, allowing doctors to keep exact digital health records of every meeting for future reference. Clynxx is focused on helping to maximise efficiency for doctors and prescribers, which is why users will now be able to create custom invoices with ease directly through the platform, with users receiving payouts directly to their bank within five days. The new update will also allow for doctors to order blood and diagnostic tests nationwide, selecting an option from options of self-test kits, partner clinics, or nursing home visits. Each test is then processed at a CQC-registered lab, ensuring the fastest and most efficient process possible. Speaking on the launch of the updated platform, Tuck Muswizu, Founder of Clynxx, added, “We are really excited to be launching this new all-in-one digital health solution for doctors. Since our launch in 2016, our mission has been to transform the UK’s private health sector to make it more efficient for doctors and patients alike. “These new features will enable UK private clinics to bring all their services online whilst increasing their capacity and reducing their workload.” A Clynxx account is completely free of charge for all GMC and GPhC regulated prescribers. Some features are priced per use. Non-members can try for free today. For more information, visit https://www.clynxx.com Company Name: CLYNXX Limited Contact Person: Ari Rox Website: https://www.clynxx.com/	cc/2022-05/en_middle_0078.json.gz/line119
__label__cc	0.52613	0.47387	Zen Player Zen Player has been inspired to make art since childhood, and his works still express a spontaneous freedom with fluid texture, vibrant color and sensually abstracted forms. Born in Southern California in 1955, Zen spent his formative years in New Zealand, where his family immigrated in the early 1960’s. From pristine surroundings and obscure art masters, he learned about light, color, composition, oil painting, ceramics, metal & wood sculpture, while gaining creative expertise with a multitude of raw materials. At age 20, Zen returned to San Francisco to further his studies at the SF Academy of Art, and enter the local gallery scene. However, the galleries were too conservative for his experimental style, so instead he worked with architects, designers and decorators who could appreciate his ability to provide totally original solutions to their needs. Over the next 20 years, Zen opened several studios in Marin County, exhibiting and contributing to private collections, homes, corporations and public spaces – including San Francisco City Hall Annex, The Fashion Institute of Technology (FIT) in New York City, Cedar Sinai Hospital in Los Angeles and others. His art has also been featured on popular album, magazine and book covers, in brochures, packaging, advertising formats and television programs, and has won prestigious art-design awards. After leaving the USA in 1996, Zen briefly returned to New Zealand, then lived in Hawaii for 3 years before settling in Byron Bay Australia. Here he creates sensuous abstract, figurative and terascape works, as well as “LightBodies”, unique illuminated sculptures made from paper & resin cast directly from the human form. The art that comes through me is an expression of joy and light in this moment, each moment of its creation. While a journey may be traced through the entire body of my works, each piece is autonomous, reflecting the totality of Presence, the sensuality of feeling, a hologram of delight. My work is art-play in the most serious sense of the term, opening a portal into a luminous Realm for all who would venture in. Life is complex, often complicated and many times confronting. When I enter this Realm of Creativity, dive into color, luxuriate in texture, tease ideas into form, the struggle of “me” disappears, the enjoyment of “I” reverberates. Time & space evaporate into the eternal moment of Now, and I am free. As a result of this active meditation, true art appears. I believe its identity is an emanation of Truth because there is no struggle, no judgment, no possession or desire to control its existence. Only awareness and appreciation, as if I had walked into a room and experienced my art for the first time. In a world where art is often categorized as decoration, intellectualism, political statement, therapy, propaganda or investment, my works find their own voice, whispering of sweet deep places within us that long to be tickled. For me, making art is like making love; a passionate and mysterious distraction touched by a desire for bliss, manifesting as waves of creative energy until they explode upon the art surface – transcending thoughts, ideas, and any concern for temporal or spiritual gain. In this ecstatic moment of orgasmic creation, we are all free. Goddess of Depth Elementelles Dolphin Queen Full Moons [wpcol_4fifth id=”” class=”” style=””] Among Stones[/wpcol_4fifth]	cc/2022-05/en_middle_0078.json.gz/line123

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