id
stringlengths
11
11
tags
stringlengths
10
777
text
stringlengths
2
1.5k
dataset_num
int64
1
3
tokens
list
ner_tags
list
NCT02832115
18:31:treatment
Previous unknown bypass grafts
3
[ "Previous", "unknown", "bypass", "grafts" ]
[ 0, 0, 1, 1 ]
NCT02641093
1:20:cancer
sinonasal carcinoma
3
[ "sinonasal", "carcinoma" ]
[ 3, 3 ]
NCT03135990
1:18:chronic_disease,26:66:chronic_disease,68:97:chronic_disease,99:128:chronic_disease
Comorbid disorder (e.g., Attention Deficit Hyperactivity Disorder, Obsessive Compulsive Disorder, Oppositional Defiant Disorder) will be allowed provided that the anxiety symptoms are of primary concern to parents and comorbid symptoms are not of sufficient severity to require immediate treatment other than that provided by the current study
3
[ "Comorbid", "disorder", "(", "e.g.", ",", "Attention", "Deficit", "Hyperactivity", "Disorder", ",", "Obsessive", "Compulsive", "Disorder", ",", "Oppositional", "Defiant", "Disorder", ")", "will", "be", "allowed", "provided", "that", "the", "anxiety", "symptoms", "are", "of", "primary", "concern", "to", "parents", "and", "comorbid", "symptoms", "are", "not", "of", "sufficient", "severity", "to", "require", "immediate", "treatment", "other", "than", "that", "provided", "by", "the", "current", "study" ]
[ 2, 2, 0, 0, 0, 2, 2, 2, 2, 0, 2, 2, 2, 0, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02040610
1:43:chronic_disease
Acquired Immune Deficiency Syndrome (AIDS) based upon current Centers for Disease Control (CDC)
3
[ "Acquired", "Immune", "Deficiency", "Syndrome", "(", "AIDS", ")", "based", "upon", "current", "Centers", "for", "Disease", "Control", "(", "CDC", ")" ]
[ 2, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02463305
23:38:treatment,,81:85:treatment,89:111:treatment,
Patients who received anti-TNF agents within 3 months of screening, or who used oral or rectal corticosteroids within 4 weeks of screening
3
[ "Patients", "who", "received", "anti-TNF", "agents", "within", "3", "months", "of", "screening", ",", "or", "who", "used", "oral", "or", "rectal", "corticosteroids", "within", "4", "weeks", "of", "screening" ]
[ 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 1, 0, 0, 0, 0, 0 ]
NCT02143726
1:25:treatment
Radioactive iodine (RAI)
3
[ "Radioactive", "iodine", "(", "RAI", ")" ]
[ 1, 1, 1, 0, 0 ]
NCT02585791
21:43:cancer,
Subjects with known pulmonary malignancies within 5 years
3
[ "Subjects", "with", "known", "pulmonary", "malignancies", "within", "5", "years" ]
[ 0, 0, 0, 3, 3, 0, 0, 0 ]
NCT01859819
4:44:chronic_disease
No congenital or acquired immune deficiency
3
[ "No", "congenital", "or", "acquired", "immune", "deficiency" ]
[ 0, 2, 2, 2, 2, 2 ]
NCT02867696
32:47:chronic_disease
Currently being treated for an eating disorder
3
[ "Currently", "being", "treated", "for", "an", "eating", "disorder" ]
[ 0, 0, 0, 0, 0, 2, 2 ]
NCT01445821
1:23:chronic_disease
Gastrointestinal tract involvement confirmed on radiological study
3
[ "Gastrointestinal", "tract", "involvement", "confirmed", "on", "radiological", "study" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT02063438
26:35:treatment,53:64:treatment,72:82:treatment,84:94:treatment
Patients requiring other incisions in addition to a thoracotomy (i.e., Laparotomy, sternotomy
3
[ "Patients", "requiring", "other", "incisions", "in", "addition", "to", "a", "thoracotomy", "(", "i.e.", ",", "Laparotomy", ",", "sternotomy" ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1 ]
NCT02307565
1:20:chronic_disease
Spinal Cord Injured
3
[ "Spinal", "Cord", "Injured" ]
[ 2, 2, 2 ]
NCT02925923
1:10:treatment
Indinavir
3
[ "Indinavir" ]
[ 1 ]
NCT02514070
28:40:treatment
Subjects requiring regular transfusions for any reason
3
[ "Subjects", "requiring", "regular", "transfusions", "for", "any", "reason" ]
[ 0, 0, 0, 1, 0, 0, 0 ]
NCT02423863
1:9:cancer
Melanoma
3
[ "Melanoma" ]
[ 3 ]
NCT02552953
22:36:cancer
Previously untreated CNS metastasis or progressive CNS metastasis
3
[ "Previously", "untreated", "CNS", "metastasis", "or", "progressive", "CNS", "metastasis" ]
[ 0, 0, 3, 3, 0, 0, 0, 0 ]
NCT01536522
1:8:allergy_name
Coconut allergies
3
[ "Coconut", "allergies" ]
[ 4, 0 ]
NCT03163901
46:59:treatment
Head, neck or back wounds that would prevent OMT treatment
3
[ "Head", ",", "neck", "or", "back", "wounds", "that", "would", "prevent", "OMT", "treatment" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02094625
1:21:chronic_disease,28:43:cancer,52:68:cancer
Disseminated disease (e.g. lepto-meningeal spread, tumor metastases)
3
[ "Disseminated", "disease", "(", "e.g", ".", "lepto-meningeal", "spread", ",", "tumor", "metastases", ")" ]
[ 2, 2, 0, 0, 0, 3, 0, 0, 3, 3, 0 ]
NCT02106598
1:22:chronic_disease,
myocardial infarction within the past 6 months
3
[ "myocardial", "infarction", "within", "the", "past", "6", "months" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT02047721
21:24:treatment
contraindication to MRI
3
[ "contraindication", "to", "MRI" ]
[ 0, 0, 1 ]
NCT02140554
,147:150:treatment
Have been treated and followed for at least the past 24 months prior to Informed Consent in medical center(s) that maintained detailed records on SCD history
3
[ "Have", "been", "treated", "and", "followed", "for", "at", "least", "the", "past", "24", "months", "prior", "to", "Informed", "Consent", "in", "medical", "center", "(", "s", ")", "that", "maintained", "detailed", "records", "on", "SCD", "history" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0 ]
NCT02482376
,,,,,,,,118:122:cancer
60 years of age or older or 50-59 with a low Oncotype score (0-17) Oncotype is not required for women diagnosed with DCIS
3
[ "60", "years", "of", "age", "or", "older", "or", "50-59", "with", "a", "low", "Oncotype", "score", "(", "0-17", ")", "Oncotype", "is", "not", "required", "for", "women", "diagnosed", "with", "DCIS" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3 ]
NCT02501473
1:22:chronic_disease,,67:83:chronic_disease,,,,137:150:chronic_disease
Myocardial infarction within 6 months of study initiation, active cardiac ischemia or New York Heart Association (NYHA) Grade III or IV heart failure
3
[ "Myocardial", "infarction", "within", "6", "months", "of", "study", "initiation", ",", "active", "cardiac", "ischemia", "or", "New", "York", "Heart", "Association", "(", "NYHA", ")", "Grade", "III", "or", "IV", "heart", "failure" ]
[ 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2 ]
NCT02346526
10:45:treatment,53:65:treatment,67:79:treatment,81:92:treatment,97:108:treatment,113:137:treatment,147:156:treatment,160:175:cancer
Received systemic therapy with radionuclides (e.g., strontium-89, samarium-153, rhenium-186, or rhenium-188, or Radium Ra 223 dichloride) for the treatment of bony metastases
3
[ "Received", "systemic", "therapy", "with", "radionuclides", "(", "e.g.", ",", "strontium-89", ",", "samarium-153", ",", "rhenium-186", ",", "or", "rhenium-188", ",", "or", "Radium", "Ra", "223", "dichloride", ")", "for", "the", "treatment", "of", "bony", "metastases" ]
[ 0, 1, 1, 1, 1, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 1, 1, 1, 0, 0, 0, 1, 0, 3, 3 ]
NCT02519322
,76:86:treatment,
WOCBP must follow instructions for birth control when the half-life of the study drug is > 24 hours
3
[ "WOCBP", "must", "follow", "instructions", "for", "birth", "control", "when", "the", "half-life", "of", "the", "study", "drug", "is", ">", "24", "hours" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0 ]
NCT01734512
48:51:treatment
Patients who do not have measurable disease on MRI
3
[ "Patients", "who", "do", "not", "have", "measurable", "disease", "on", "MRI" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02186418
18:41:chronic_disease,,148:166:chronic_disease,186:206:treatment,,344:371:treatment
Frequent painful vaso-occlusive episodes which significantly interfere with normal life activities, defined as a history of 2 or more severe acute sickle pain events per year requiring additional treatment at a medical facility outside of home pain management over the preceding two year period prior to study enrollment, or which necessitate chronic transfusion therapy
3
[ "Frequent", "painful", "vaso-occlusive", "episodes", "which", "significantly", "interfere", "with", "normal", "life", "activities", ",", "defined", "as", "a", "history", "of", "2", "or", "more", "severe", "acute", "sickle", "pain", "events", "per", "year", "requiring", "additional", "treatment", "at", "a", "medical", "facility", "outside", "of", "home", "pain", "management", "over", "the", "preceding", "two", "year", "period", "prior", "to", "study", "enrollment", ",", "or", "which", "necessitate", "chronic", "transfusion", "therapy" ]
[ 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 2, 2, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1 ]
NCT02236013
,,,174:184:treatment
must use two forms of birth control* (at least one of which must be a barrier method) starting at Screening and throughout the study period and for 180 days after the final study drug administration
3
[ "must", "use", "two", "forms", "of", "birth", "control", "*", "(", "at", "least", "one", "of", "which", "must", "be", "a", "barrier", "method", ")", "starting", "at", "Screening", "and", "throughout", "the", "study", "period", "and", "for", "180", "days", "after", "the", "final", "study", "drug", "administration" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02213289
21:31:cancer,36:55:chronic_disease,136:145:treatment,,,
Consent to baseline metastatic and progressive disease biopsy (of metastatic/progressing lesion) for enabling biomarker assessment and treatment assignment (at each time point - baseline, PD1, PD2, PD3) as well as for correlative studies
3
[ "Consent", "to", "baseline", "metastatic", "and", "progressive", "disease", "biopsy", "(", "of", "metastatic/progressing", "lesion", ")", "for", "enabling", "biomarker", "assessment", "and", "treatment", "assignment", "(", "at", "each", "time", "point", "-", "baseline", ",", "PD1", ",", "PD2", ",", "PD3", ")", "as", "well", "as", "for", "correlative", "studies" ]
[ 0, 0, 0, 3, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02765425
,21:40:treatment
<70% correct on the Joint Position Test
3
[ "<", "70", "%", "correct", "on", "the", "Joint", "Position", "Test" ]
[ 0, 0, 0, 0, 0, 0, 1, 1, 1 ]
NCT02099058
26:36:cancer,87:89:treatment,93:96:treatment
Subject has uncontrolled metastases to the central nervous system (CNS) based on head CT or MRI
3
[ "Subject", "has", "uncontrolled", "metastases", "to", "the", "central", "nervous", "system", "(", "CNS", ")", "based", "on", "head", "CT", "or", "MRI" ]
[ 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1 ]
NCT02418195
1:10:treatment,37:48:treatment,116:127:treatment,129:140:treatment,142:151:treatment,153:161:treatment,166:173:treatment
Treatment with one of the following medications, known to affect the glutamate-NMDA receptor system (specifically: lamotrigine, acamprosate, memantine, riluzole, or lithium)
3
[ "Treatment", "with", "one", "of", "the", "following", "medications", ",", "known", "to", "affect", "the", "glutamate-NMDA", "receptor", "system", "(", "specifically", ":", "lamotrigine", ",", "acamprosate", ",", "memantine", ",", "riluzole", ",", "or", "lithium", ")" ]
[ 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0 ]
NCT01618357
,,45:48:treatment
Women who have a < 1.0 cm and are cN0 after NAC
3
[ "Women", "who", "have", "a", "<", "1.0", "cm", "and", "are", "cN0", "after", "NAC" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02187198
33:49:treatment
requirement for current ongoing opioid treatment for adequate pain management
3
[ "requirement", "for", "current", "ongoing", "opioid", "treatment", "for", "adequate", "pain", "management" ]
[ 0, 0, 0, 0, 1, 1, 0, 0, 0, 0 ]
NCT02131467
1:28:chronic_disease
Secondary cervical dystonia
3
[ "Secondary", "cervical", "dystonia" ]
[ 2, 2, 2 ]
NCT02470897
26:46:treatment
Up to a total of year of androgen deprivation allowed
3
[ "Up", "to", "a", "total", "of", "year", "of", "androgen", "deprivation", "allowed" ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 1, 0 ]
NCT01737502
1:19:chronic_disease
Cardiac arrhythmia
3
[ "Cardiac", "arrhythmia" ]
[ 2, 2 ]
NCT02278250
1:13:treatment,39:57:treatment,59:76:treatment,78:101:treatment,103:116:treatment,121:133:treatment,,,166:178:treatment,183:194:treatment,290:300:treatment
Radiotherapy, unless brief course for palliative therapy, endocrine therapy, target-specific therapy, immunotherapy, or chemotherapy during the 4 weeks (6 weeks for nitrosoureas and Mitomycin-C, and 4 weeks for investigational medicinal products) or 4 drug half-lives before first dose of study drug, whichever is greater
3
[ "Radiotherapy", ",", "unless", "brief", "course", "for", "palliative", "therapy", ",", "endocrine", "therapy", ",", "target-specific", "therapy", ",", "immunotherapy", ",", "or", "chemotherapy", "during", "the", "4", "weeks", "(", "6", "weeks", "for", "nitrosoureas", "and", "Mitomycin-C", ",", "and", "4", "weeks", "for", "investigational", "medicinal", "products", ")", "or", "4", "drug", "half-lives", "before", "first", "dose", "of", "study", "drug", ",", "whichever", "is", "greater" ]
[ 1, 0, 0, 0, 0, 0, 1, 1, 0, 1, 1, 0, 1, 1, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0 ]
NCT03085004
1:30:cancer
epithelial type mural nodules
3
[ "epithelial", "type", "mural", "nodules" ]
[ 3, 3, 3, 3 ]
NCT01822522
30:45:treatment,53:84:treatment,90:106:treatment,,,284:299:treatment
The participant has received prior treatment with a small molecule kinase inhibitor or a hormonal therapy (including investigational kinase inhibitors or hormones) within 4 weeks or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment
3
[ "The", "participant", "has", "received", "prior", "treatment", "with", "a", "small", "molecule", "kinase", "inhibitor", "or", "a", "hormonal", "therapy", "(", "including", "investigational", "kinase", "inhibitors", "or", "hormones", ")", "within", "4", "weeks", "or", "five", "half-lives", "of", "the", "compound", "or", "active", "metabolites", ",", "whichever", "is", "longer", ",", "before", "the", "first", "dose", "of", "study", "treatment" ]
[ 0, 0, 0, 0, 1, 1, 0, 0, 1, 1, 1, 1, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT01878617
5:20:cancer,32:47:cancer,51:55:cancer
CNS embryonal tumor other than medulloblastoma or PNET in the posterior fossa
3
[ "CNS", "embryonal", "tumor", "other", "than", "medulloblastoma", "or", "PNET", "in", "the", "posterior", "fossa" ]
[ 0, 3, 3, 0, 0, 3, 0, 3, 0, 0, 0, 0 ]
NCT03175978
1:13:treatment,
methotrexate is Pregnancy Category X - has been reported to cause fetal death and/or congenital abnormalities
3
[ "methotrexate", "is", "Pregnancy", "Category", "X", "-", "has", "been", "reported", "to", "cause", "fetal", "death", "and/or", "congenital", "abnormalities" ]
[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02991144
12:25:chronic_disease
History of liver disease
3
[ "History", "of", "liver", "disease" ]
[ 0, 0, 2, 2 ]
NCT01959425
10:58:treatment,
Awaiting cardiac transplantation or other cardiac surgery within the next 365 days (12 months)
3
[ "Awaiting", "cardiac", "transplantation", "or", "other", "cardiac", "surgery", "within", "the", "next", "365", "days", "(", "12", "months", ")" ]
[ 0, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02312596
5:10:chronic_disease,
The ulcer is greater than 4 weeks duration
3
[ "The", "ulcer", "is", "greater", "than", "4", "weeks", "duration" ]
[ 0, 2, 0, 0, 0, 0, 0, 0 ]
NCT01787409
1:23:cancer
primary cutaneous type
3
[ "primary", "cutaneous", "type" ]
[ 3, 3, 3 ]
NCT02698722
9:14:chronic_disease
Legally blind
3
[ "Legally", "blind" ]
[ 0, 2 ]
NCT03135171
1:14:treatment,26:46:treatment,48:53:treatment,55:65:treatment,67:76:treatment
Prior therapy with other HER2 targeted agents (TDM-1, pertuzumab, lapatinib)
3
[ "Prior", "therapy", "with", "other", "HER2", "targeted", "agents", "(", "TDM-1", ",", "pertuzumab", ",", "lapatinib", ")" ]
[ 1, 1, 0, 0, 1, 1, 1, 0, 1, 0, 1, 0, 1, 0 ]
NCT01582191
14:34:chronic_disease,66:88:chronic_disease,90:109:chronic_disease,120:132:treatment,143:162:treatment
Uncontrolled intercurrent illness including, but not limited to, uncontrolled infection, uncontrolled asthma, need for hemodialysis, need for ventilatory support
3
[ "Uncontrolled", "intercurrent", "illness", "including", ",", "but", "not", "limited", "to", ",", "uncontrolled", "infection", ",", "uncontrolled", "asthma", ",", "need", "for", "hemodialysis", ",", "need", "for", "ventilatory", "support" ]
[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 1 ]
NCT01970176
13:33:treatment,
Received an investigational drug within 1 month prior to dosing
3
[ "Received", "an", "investigational", "drug", "within", "1", "month", "prior", "to", "dosing" ]
[ 0, 0, 1, 1, 0, 0, 0, 0, 0, 0 ]
NCT02516670
14:21:treatment,,53:74:treatment,86:102:treatment,104:115:treatment,117:128:treatment,137:156:treatment,162:185:treatment
Have had had surgery within four weeks of dosing of investigational agent, excluding minor procedures (dental work, skin biopsy, etc.), celiac plexus block, and biliary stent placement
3
[ "Have", "had", "had", "surgery", "within", "four", "weeks", "of", "dosing", "of", "investigational", "agent", ",", "excluding", "minor", "procedures", "(", "dental", "work", ",", "skin", "biopsy", ",", "etc", ".", ")", ",", "celiac", "plexus", "block", ",", "and", "biliary", "stent", "placement" ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 1, 1, 0, 1, 1, 0, 1, 1, 0, 0, 0, 0, 0, 1, 1, 1, 0, 0, 1, 1, 1 ]
NCT02193841
,48:62:treatment
At least 3 months must have elapsed since last cyst treatment
3
[ "At", "least", "3", "months", "must", "have", "elapsed", "since", "last", "cyst", "treatment" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02261519
1:26:chronic_disease,35:58:chronic_disease,60:73:chronic_disease,77:90:chronic_disease
Serious medical illnesses such as end-stage renal disease, liver failure or heart failure that, in the opinion of the Investigator, may interfere with the conduct of the study
3
[ "Serious", "medical", "illnesses", "such", "as", "end-stage", "renal", "disease", ",", "liver", "failure", "or", "heart", "failure", "that", ",", "in", "the", "opinion", "of", "the", "Investigator", ",", "may", "interfere", "with", "the", "conduct", "of", "the", "study" ]
[ 2, 2, 2, 0, 0, 2, 2, 2, 0, 2, 2, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01659203
1:16:chronic_disease,
Life expectancy of greater than 2 years
3
[ "Life", "expectancy", "of", "greater", "than", "2", "years" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT02091141
27:51:allergy_name
Known hypersensitivity to biopharmaceutical agents produced in Chinese hamster ovary cells
3
[ "Known", "hypersensitivity", "to", "biopharmaceutical", "agents", "produced", "in", "Chinese", "hamster", "ovary", "cells" ]
[ 0, 0, 0, 4, 4, 0, 0, 0, 0, 0, 0 ]
NCT01851369
22:38:cancer,42:66:cancer,,,252:259:treatment,264:288:treatment
Patients with active brain metastases or carcinomatous meningitis are excluded from this clinical trial. Patients with treated brain metastases, whose brain metastatic disease has remained stable for greater than or equal to 4 weeks without requiring steroid and anti-seizure medications are eligible to participate
3
[ "Patients", "with", "active", "brain", "metastases", "or", "carcinomatous", "meningitis", "are", "excluded", "from", "this", "clinical", "trial", ".", "Patients", "with", "treated", "brain", "metastases", ",", "whose", "brain", "metastatic", "disease", "has", "remained", "stable", "for", "greater", "than", "or", "equal", "to", "4", "weeks", "without", "requiring", "steroid", "and", "anti-seizure", "medications", "are", "eligible", "to", "participate" ]
[ 0, 0, 0, 3, 3, 0, 3, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 1, 0, 0, 0, 0 ]
NCT01684904
1:19:treatment
Prior radiotherapy that would results in overlap of radiation fields
3
[ "Prior", "radiotherapy", "that", "would", "results", "in", "overlap", "of", "radiation", "fields" ]
[ 1, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01913106
92:119:treatment
Nutritional and general physical condition must be considered compatible with the proposed radio-therapeutic treatment
3
[ "Nutritional", "and", "general", "physical", "condition", "must", "be", "considered", "compatible", "with", "the", "proposed", "radio-therapeutic", "treatment" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT00670358
1:37:chronic_disease
Symptomatic congestive heart failure
3
[ "Symptomatic", "congestive", "heart", "failure" ]
[ 2, 2, 2, 2 ]
NCT02271711
1:20:chronic_disease,
Neurologic deficits must have been relatively stable for a minimum of 1 week prior to study enrollment
3
[ "Neurologic", "deficits", "must", "have", "been", "relatively", "stable", "for", "a", "minimum", "of", "1", "week", "prior", "to", "study", "enrollment" ]
[ 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02910700
,14:24:treatment
> 8 mg daily prednisone equivalents
3
[ ">", "8", "mg", "daily", "prednisone", "equivalents" ]
[ 0, 0, 0, 0, 1, 0 ]
NCT02503722
22:34:cancer,46:51:cancer,55:90:treatment,171:179:cancer,183:206:cancer
Patients with active malignancies other than NSCLC or prior curatively treated malignancy at high risk of relapse during the study period with the exception of localized squamous or basal cell skin cancers
3
[ "Patients", "with", "active", "malignancies", "other", "than", "NSCLC", "or", "prior", "curatively", "treated", "malignancy", "at", "high", "risk", "of", "relapse", "during", "the", "study", "period", "with", "the", "exception", "of", "localized", "squamous", "or", "basal", "cell", "skin", "cancers" ]
[ 0, 0, 0, 3, 0, 0, 3, 0, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 3, 3, 3, 3 ]
NCT02500602
30:44:treatment,46:55:treatment,57:65:treatment,68:93:treatment,95:118:treatment,120:130:treatment,132:142:treatment,144:155:treatment,157:166:treatment,169:185:treatment,187:196:treatment,198:208:treatment,210:220:treatment,222:232:treatment,235:245:treatment,247:257:treatment,259:269:treatment,271:287:treatment,291:310:treatment,312:331:treatment,333:342:treatment,346:349:chronic_disease,352:368:treatment,370:379:treatment,381:390:treatment,392:401:treatment,403:412:treatment,417:426:treatment
Individuals currently taking alpha blockers (terazosin, prazosin), hypnotics/benzodiazepines, atypical antipsychotics (olanzapine, quetiapine, risperidone, clozapine), alpha-2-agonists (Clonidine, methyldopa, tizanidine, guanfacine), conivaptan, boceprevir, idelalisib, PDE-5 inhibitors or alpha-1-antagonists, protease inhibitors (treatment of HIV), oral antifungals, alfuzosin, pazopanib, silodosin, tadalafil, or tamulosin
3
[ "Individuals", "currently", "taking", "alpha", "blockers", "(", "terazosin", ",", "prazosin", ")", ",", "hypnotics/benzodiazepines", ",", "atypical", "antipsychotics", "(", "olanzapine", ",", "quetiapine", ",", "risperidone", ",", "clozapine", ")", ",", "alpha-2-agonists", "(", "Clonidine", ",", "methyldopa", ",", "tizanidine", ",", "guanfacine", ")", ",", "conivaptan", ",", "boceprevir", ",", "idelalisib", ",", "PDE-5", "inhibitors", "or", "alpha-1-antagonists", ",", "protease", "inhibitors", "(", "treatment", "of", "HIV", ")", ",", "oral", "antifungals", ",", "alfuzosin", ",", "pazopanib", ",", "silodosin", ",", "tadalafil", ",", "or", "tamulosin" ]
[ 0, 0, 0, 1, 1, 0, 1, 0, 1, 0, 0, 1, 0, 1, 1, 0, 1, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0, 1, 0, 1, 0, 1, 0, 1, 0, 0, 1, 0, 1, 0, 1, 0, 1, 1, 0, 1, 0, 1, 1, 0, 1, 0, 2, 0, 0, 1, 1, 0, 1, 0, 1, 0, 1, 0, 1, 0, 0, 1 ]
NCT02509507
37:52:treatment,56:76:treatment,80:92:cancer,125:163:treatment
Subjects must not be candidates for hepatic surgery or locoregional therapy of liver tumors with curative intent or planned immediate systemic anti-cancer therapy
3
[ "Subjects", "must", "not", "be", "candidates", "for", "hepatic", "surgery", "or", "locoregional", "therapy", "of", "liver", "tumors", "with", "curative", "intent", "or", "planned", "immediate", "systemic", "anti-cancer", "therapy" ]
[ 0, 0, 0, 0, 0, 0, 1, 1, 0, 1, 1, 0, 3, 3, 0, 0, 0, 0, 0, 1, 1, 1, 1 ]
NCT02106598
17:34:cancer
Newly-diagnosed colorectal cancer patients in whom SLN mapping and total mesorectal excision with lateral pelvic sidewall dissection is indicated
3
[ "Newly-diagnosed", "colorectal", "cancer", "patients", "in", "whom", "SLN", "mapping", "and", "total", "mesorectal", "excision", "with", "lateral", "pelvic", "sidewall", "dissection", "is", "indicated" ]
[ 0, 3, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02036853
15:23:chronic_disease
Patients with GLUT1 DS by physician diagnosis
3
[ "Patients", "with", "GLUT1", "DS", "by", "physician", "diagnosis" ]
[ 0, 0, 2, 2, 0, 0, 0 ]
NCT02588027
31:39:treatment,41:51:treatment,53:60:treatment,67:76:treatment,88:115:treatment
Patients who are currently on warfarin, enoxaparin, heparin, or a factor Xa inhibiting anti-coagulation medication
3
[ "Patients", "who", "are", "currently", "on", "warfarin", ",", "enoxaparin", ",", "heparin", ",", "or", "a", "factor", "Xa", "inhibiting", "anti-coagulation", "medication" ]
[ 0, 0, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 1, 1, 0, 1, 1 ]
NCT02931110
1:40:treatment
hematopoietic stem cell transplantation
3
[ "hematopoietic", "stem", "cell", "transplantation" ]
[ 1, 1, 1, 1 ]
NCT02203513
1:13:chronic_disease,81:101:treatment,106:117:chronic_disease
valvulopathy that is severe, moderate, or deemed clinically significant despite medical intervention; or arrhythmias that are symptomatic or refractory to medical intervention
3
[ "valvulopathy", "that", "is", "severe", ",", "moderate", ",", "or", "deemed", "clinically", "significant", "despite", "medical", "intervention", ";", "or", "arrhythmias", "that", "are", "symptomatic", "or", "refractory", "to", "medical", "intervention" ]
[ 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02044120
13:26:cancer,44:48:treatment,52:58:treatment
Evidence of Ewing sarcoma translocation by FISH or RT-PCR
3
[ "Evidence", "of", "Ewing", "sarcoma", "translocation", "by", "FISH", "or", "RT-PCR" ]
[ 0, 0, 3, 3, 0, 0, 1, 0, 1 ]
NCT02579265
8:29:chronic_disease
Active bloodstream infection demonstrated by positive blood culture at screening
3
[ "Active", "bloodstream", "infection", "demonstrated", "by", "positive", "blood", "culture", "at", "screening" ]
[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0 ]
NCT01993810
1:28:chronic_disease
Exudative pleural effusions are excluded, regardless of cytology
3
[ "Exudative", "pleural", "effusions", "are", "excluded", ",", "regardless", "of", "cytology" ]
[ 2, 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT02214667
1:32:chronic_disease
schizophrenia spectrum disorder
3
[ "schizophrenia", "spectrum", "disorder" ]
[ 2, 2, 2 ]
NCT02307058
13:32:treatment
No previous pelvic radiotherapy
3
[ "No", "previous", "pelvic", "radiotherapy" ]
[ 0, 0, 1, 1 ]
NCT02485418
9:17:chronic_disease,,,,,,
Current migraine has a greater than 24 hours duration with a current pain score of 6 or greater on a 0-10 Numeric Pain Rating Scale
3
[ "Current", "migraine", "has", "a", "greater", "than", "24", "hours", "duration", "with", "a", "current", "pain", "score", "of", "6", "or", "greater", "on", "a", "0-10", "Numeric", "Pain", "Rating", "Scale" ]
[ 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02414139
38:52:chronic_disease
Clinically significant, uncontrolled heart diseases
3
[ "Clinically", "significant", ",", "uncontrolled", "heart", "diseases" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT02203552
1:21:chronic_disease,41:51:chronic_disease,56:82:chronic_disease,106:120:chronic_disease,125:137:chronic_disease
Rheumatoid arthritis and other types of autoimmune and inflammatory joint disease, with the exception of osteoarthritis and fibromyalgia
3
[ "Rheumatoid", "arthritis", "and", "other", "types", "of", "autoimmune", "and", "inflammatory", "joint", "disease", ",", "with", "the", "exception", "of", "osteoarthritis", "and", "fibromyalgia" ]
[ 2, 2, 0, 0, 0, 0, 2, 0, 2, 2, 2, 0, 0, 0, 0, 0, 2, 0, 2 ]
NCT02580604
1:36:chronic_disease,,
Moderate or severe renal impairment defined as an estimated glomerular filtration rate of <60 mL/min/1.73m2 based on the Modified Diet in Renal Disease (MDRD) equation
3
[ "Moderate", "or", "severe", "renal", "impairment", "defined", "as", "an", "estimated", "glomerular", "filtration", "rate", "of", "<", "60", "mL/min/1.73m2", "based", "on", "the", "Modified", "Diet", "in", "Renal", "Disease", "(", "MDRD", ")", "equation" ]
[ 2, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02099591
17:29:chronic_disease,43:52:treatment,95:111:treatment
with history of constipation treated with laxatives or expected to develop constipation after opioid treatment
3
[ "with", "history", "of", "constipation", "treated", "with", "laxatives", "or", "expected", "to", "develop", "constipation", "after", "opioid", "treatment" ]
[ 0, 0, 0, 2, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT03174444
18:35:cancer
Not eligible for colorectal cancer screening for any reason
3
[ "Not", "eligible", "for", "colorectal", "cancer", "screening", "for", "any", "reason" ]
[ 0, 0, 0, 3, 3, 0, 0, 0, 0 ]
NCT01804634
131:144:cancer
Patients with high risk disease as defined in Appendix 1 whose autologous peripheral blood stem cell product is contaminated with neuroblastoma or who do not have an autologous product available
3
[ "Patients", "with", "high", "risk", "disease", "as", "defined", "in", "Appendix", "1", "whose", "autologous", "peripheral", "blood", "stem", "cell", "product", "is", "contaminated", "with", "neuroblastoma", "or", "who", "do", "not", "have", "an", "autologous", "product", "available" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01050855
1:31:chronic_disease
adenosine deaminase deficiency
3
[ "adenosine", "deaminase", "deficiency" ]
[ 2, 2, 2 ]
NCT01757418
18:32:allergy_name
known allergy to gamma globulin
3
[ "known", "allergy", "to", "gamma", "globulin" ]
[ 0, 0, 0, 4, 4 ]
NCT02091999
25:42:chronic_disease,46:65:chronic_disease,,103:113:treatment
History of uncontrolled diabetes mellitus or diabetic neuropathy within 3 months of the first dose of study drug
3
[ "History", "of", "uncontrolled", "diabetes", "mellitus", "or", "diabetic", "neuropathy", "within", "3", "months", "of", "the", "first", "dose", "of", "study", "drug" ]
[ 0, 0, 0, 2, 2, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02203903
1:29:cancer
Acute myeloid leukemia (AML)
3
[ "Acute", "myeloid", "leukemia", "(", "AML", ")" ]
[ 3, 3, 3, 3, 0, 0 ]
NCT02527200
47:60:chronic_disease
Suggestive history of, or significant risk of gastroparesis (e.g. marked abdominal bloating post meal, history of vomiting, severe constipation), as judged by the Investigator
3
[ "Suggestive", "history", "of", ",", "or", "significant", "risk", "of", "gastroparesis", "(", "e.g", ".", "marked", "abdominal", "bloating", "post", "meal", ",", "history", "of", "vomiting", ",", "severe", "constipation", ")", ",", "as", "judged", "by", "the", "Investigator" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02504866
1:26:chronic_disease,,
Uncontrolled hypertension, defined as a resting blood pressure > 140/90 mmHg
3
[ "Uncontrolled", "hypertension", ",", "defined", "as", "a", "resting", "blood", "pressure", ">", "140/90", "mmHg" ]
[ 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT00737893
17:63:treatment
The patient has planned pre or post operative androgen therapy
3
[ "The", "patient", "has", "planned", "pre", "or", "post", "operative", "androgen", "therapy" ]
[ 0, 0, 0, 1, 1, 1, 1, 1, 1, 1 ]
NCT01449149
1:38:cancer
giant cell tumor aneurismal bone cyst
3
[ "giant", "cell", "tumor", "aneurismal", "bone", "cyst" ]
[ 3, 3, 3, 3, 3, 3 ]
NCT02140554
10:23:chronic_disease
Advanced liver disease
3
[ "Advanced", "liver", "disease" ]
[ 0, 2, 2 ]
NCT01760005
12:18:cancer,,51:71:cancer,73:100:cancer,102:117:cancer,121:138:cancer,
History of cancer within the last 5 years, except basal cell carcinoma, non-squamous skin carcinoma, prostate cancer or carcinoma in situ with no significant progression over the past 2 years
3
[ "History", "of", "cancer", "within", "the", "last", "5", "years", ",", "except", "basal", "cell", "carcinoma", ",", "non-squamous", "skin", "carcinoma", ",", "prostate", "cancer", "or", "carcinoma", "in", "situ", "with", "no", "significant", "progression", "over", "the", "past", "2", "years" ]
[ 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 3, 3, 3, 3, 3, 3, 3, 0, 3, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02519322
19:35:cancer,45:50:cancer,51:57:treatment,82:96:cancer
for patients with stage IV disease, site of tumor biopsy will preferably be from non-lymph node disease site
3
[ "for", "patients", "with", "stage", "IV", "disease", ",", "site", "of", "tumor", "biopsy", "will", "preferably", "be", "from", "non-lymph", "node", "disease", "site" ]
[ 0, 0, 0, 3, 3, 3, 0, 0, 0, 3, 1, 0, 0, 0, 0, 3, 3, 0, 0 ]
NCT02624765
1:34:chronic_disease
life-threatening maternal disease
3
[ "life-threatening", "maternal", "disease" ]
[ 2, 2, 2 ]
NCT02338232
1:25:cancer
Myelodysplastic syndrome
3
[ "Myelodysplastic", "syndrome" ]
[ 3, 3 ]
NCT02845596
9:35:cancer
treated cervical carcinoma in situ
3
[ "treated", "cervical", "carcinoma", "in", "situ" ]
[ 0, 3, 3, 3, 3 ]
NCT01444209
28:47:cancer
Patients with diagnosis of pituitary carcinoma
3
[ "Patients", "with", "diagnosis", "of", "pituitary", "carcinoma" ]
[ 0, 0, 0, 0, 3, 3 ]
NCT02099058
26:34:treatment,55:66:treatment,68:77:treatment,81:90:treatment
Subjects may not receive ABBV-399 in combination with osimertinib, erlotinib or nivolumab if they have any medical condition which in the opinion of the Investigator places the subject at an unacceptably high risk for toxicities from the combination
3
[ "Subjects", "may", "not", "receive", "ABBV-399", "in", "combination", "with", "osimertinib", ",", "erlotinib", "or", "nivolumab", "if", "they", "have", "any", "medical", "condition", "which", "in", "the", "opinion", "of", "the", "Investigator", "places", "the", "subject", "at", "an", "unacceptably", "high", "risk", "for", "toxicities", "from", "the", "combination" ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02679560
1:23:chronic_disease
Distal femur fractures
3
[ "Distal", "femur", "fractures" ]
[ 2, 2, 2 ]
NCT02140554
37:47:allergy_name
Any contraindications to the use of plerixafor during the mobilization of hematopoietic stem cells
3
[ "Any", "contraindications", "to", "the", "use", "of", "plerixafor", "during", "the", "mobilization", "of", "hematopoietic", "stem", "cells" ]
[ 0, 0, 0, 0, 0, 0, 4, 0, 0, 0, 0, 0, 0, 0 ]