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NCT01766297
|
14:24:cancer
|
negative for malignancy on pathology
| 1
|
[
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NCT02012296
|
,26:35:treatment
|
2 or more new lesions on bone scan
| 1
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NCT01940757
|
26:38:chronic_disease,,,,
|
Laboratory evidence of a coagulopathy (PTT or PT INR greater than 1.1-times the upper reference limit)
| 1
|
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NCT01445821
|
20:45:chronic_disease
|
Occult or clinical constrictive pericarditis
| 1
|
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NCT02436070
|
61:67:chronic_disease,110:130:chronic_disease,132:140:chronic_disease
|
Presentation to the ED with a chief complaint related to an asthma exacerbation such as shortness of breath, respiratory distress, wheezing, etc
| 1
|
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NCT02592707
|
1:13:treatment,
|
Chemotherapy ≤ 3 months before enrolment
| 1
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NCT01908777
|
29:39:treatment
|
who are deemed eligible for transplant by their treating physician Disease status: CR or PR required
| 1
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NCT02257424
|
12:22:cancer,
|
History of malignancy other than disease under study within 3 years of study enrollment
| 1
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NCT02324582
|
10:23:treatment,32:41:treatment,43:53:treatment,55:65:treatment,67:77:treatment,82:148:treatment,160:170:treatment,280:289:treatment,294:314:treatment
|
received prior therapy with an anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CD137, or anti-Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) antibody (including ipilimumab or any other antibody or drug specifically targeting T-cell co-stimulation or checkpoint pathways) including anti-CD40 and anti-OX40 antibodies
| 1
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NCT01890590
|
67:104:cancer,,,171:174:treatment,178:185:treatment
|
Participants must have histologically or radiological evidence of Stage I (T1N0M0) renal cell carcinoma with a size no larger than 8 cm in greatest dimension measured by MRI or CT Scan
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NCT01920061
|
1:35:cancer,37:59:cancer,64:91:cancer,116:160:treatment
|
castrate resistant prostate cancer, advanced breast cancer, or non-small cell lunch cancer that are candidates for treatment with a docetaxel-based combination
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NCT03030118
|
1:60:chronic_disease
|
Active bacterial, viral, fungal, or opportunistic infection
| 1
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NCT01595529
|
95:105:treatment
|
A child whose urine culture reveals an organism that is resistant to the initially prescribed antibiotic
| 1
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NCT02544503
|
13:30:chronic_disease
|
Moderate or severe depression
| 1
|
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0,
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NCT02544503
|
8:24:treatment
|
Normal MRI of the brain
| 1
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NCT02091141
|
40:59:treatment,,91:106:cancer,117:134:treatment,137:152:treatment,157:166:treatment,,277:285:chronic_disease,287:304:treatment,
|
Concurrent administration of any other anti-cancer therapy (except male participants with prostate cancer receiving androgen blockade): Bisphosphonates and denosumab are allowed; Most recent anti-cancer therapy ≤28 days and have not recovered from the side effects, excluding alopecia; Radiation therapy within ≤14 days
| 1
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NCT02091999
|
21:31:chronic_disease,,
|
Preexisting sensory neuropathy Grade ≥ 2
| 1
|
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NCT02287558
|
,39:83:treatment
|
Recurrent bleeding after at least one previous interventional endoscopic procedure
| 1
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NCT02273375
|
14:35:chronic_disease
|
known active hepatitis C infection
| 1
|
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0,
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NCT02251431
|
1:28:treatment,30:43:treatment,45:58:treatment,69:94:treatment
|
Implanted cardiac pacemaker, defibrillator, loop recorder, or other implanted metallic device
| 1
|
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NCT02836574
|
44:70:treatment
|
subject is not a good candidate to undergo percutaneous NKA injection, in the judgment of the surgeon or physician who will perform the procedure
| 1
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NCT03026816
|
9:34:chronic_disease
|
Stable, motor-complete paraplegia
| 1
|
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NCT01617161
|
1:15:treatment,17:43:chronic_disease,47:73:chronic_disease,89:100:chronic_disease,104:109:chronic_disease
|
Hip prosthesis, inflammatory bowel disease or connective tissue disorder such as active scleroderma or lupus
| 1
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NCT02360579
|
113:139:chronic_disease,150:162:treatment,164:185:chronic_disease
|
Patients who have active medical illness(es) that would pose increased risk for study participation, including: active systemic infections requiring systemic ABX, coagulation disorders, or other active major medical illnesses of the cardiovascular, respiratory, or immune system
| 1
|
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NCT02176967
|
,,,51:64:cancer,
|
> 6 months and < 12 months of age with an adrenal primary tumor < 5 cm in greatest diameter
| 1
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NCT02955537
|
1:13:chronic_disease
|
Hypertensive
| 1
|
[
"Hypertensive"
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[
2
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NCT02940288
|
19:30:treatment
|
Patients naïve to acupuncture
| 1
|
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NCT03168347
|
16:25:chronic_disease
|
Diagnosed with psoriasis (ICD-9: 696.1)
| 1
|
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NCT02547818
|
1:23:treatment,
|
Investigational agents are prohibited one month prior to entry and for the duration of the trial
| 1
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NCT02937402
|
1:29:treatment,31:41:treatment,43:53:treatment,55:65:treatment,70:90:treatment,102:112:treatment,166:172:cancer
|
Prior therapy with anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CD137, or anti-CTLA-4 antibody (including ipilimumab or any other antibody or drug specifically targeting T-cell co-stimulation or checkpoint pathways)
| 1
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NCT02991651
|
12:28:chronic_disease
|
ongoing or active infection
| 1
|
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0,
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NCT03004807
|
1:12:chronic_disease,,
|
Head injury with loss of consciousness of > 5 minutes in the last 5 years
| 1
|
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NCT01620216
|
26:34:cancer,65:97:cancer,101:135:cancer
|
with relapsed/refractory leukemia with a confirmed diagnosis of acute myelogenous leukemia (AML) or acute lymphoblastic leukemia (ALL)
| 1
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NCT01869114
|
1:4:cancer,8:11:cancer,30:60:treatment,49:60:treatment
|
MDS or AML as above BUT with prior therapy with Azacitibine (Arm C): Patients who meet criteria for either Arm A or Arm B but have been treated or are currently treated with Azacitibine
| 1
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NCT01869114
|
96:105:treatment
|
Patients must be able to sign consent and be willing and able to comply with scheduled visits, treatment plan and laboratory testing
| 1
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NCT02291523
|
37:46:treatment,,65:70:treatment,72:80:treatment,84:100:treatment
|
Children with recent dose change of biologics (within 4 weeks), 5-ASA, steroids or immunomodulators (within 4 weeks)
| 1
|
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NCT02233868
|
1:15:treatment
|
anticoagulants
| 1
|
[
"anticoagulants"
] |
[
1
] |
NCT03088592
|
47:57:chronic_disease,,
|
Currently uncontrolled clinically significant depression (BDI>20)
| 1
|
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NCT02960113
|
1:15:chronic_disease
|
Coagulopathies
| 1
|
[
"Coagulopathies"
] |
[
2
] |
NCT01367444
|
33:42:treatment
|
Enrolment in any other clinical treatment study throughout the duration of the SAR422459 study
| 1
|
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] |
NCT01817751
|
29:44:treatment,
|
Fixed or decreasing dose of corticosteroids (or no corticosteroids) for at least 1 week prior to cycle 1 day 1
| 1
|
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NCT02158793
|
,,41:51:treatment,,,,
|
Negative pregnancy test within 48hrs of transplant for women of childbearing age and who agree to use a reliable form of contraception for one year following transplant
| 1
|
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NCT02862210
|
18:34:chronic_disease,38:51:chronic_disease,55:79:chronic_disease
|
The diagnosis of bipolar disorder or schizophrenia or schizoaffective disorder
| 1
|
[
"The",
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NCT02446457
|
,,106:116:treatment
|
have a negative urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication
| 1
|
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NCT02102113
|
21:30:treatment
|
Current or lifetime treatment
| 1
|
[
"Current",
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"treatment"
] |
[
0,
0,
0,
1
] |
NCT01912612
|
14:35:chronic_disease
|
Uncontrolled narrow-angle glaucoma
| 1
|
[
"Uncontrolled",
"narrow-angle",
"glaucoma"
] |
[
0,
2,
2
] |
NCT02535312
|
16:22:treatment,118:136:treatment,,,,,,,425:436:treatment
|
The effects of TRC102 on the developing human fetus are unknown; for this reason and because TRC102 as well as other therapeutic agents used in this trial are known to be teratogenic, women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and 4 months after completion of the study drugs
| 1
|
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NCT00075387
|
,114:138:chronic_disease
|
Subjects with uncontrolled (over the last 30 days) clinically significant confounding medical conditions such as congestive heart failure
| 1
|
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NCT01849146
|
20:30:cancer,57:62:cancer,66:101:cancer,105:136:cancer,138:144:cancer,149:156:cancer
|
have no concurrent malignancy except curatively treated basal or squamous cell carcinoma of the skin or carcinoma in situ of the cervix, breast, or bladder
| 1
|
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NCT02594501
|
56:59:allergy_name,61:72:allergy_name,74:82:allergy_name
|
Known allergy or intolerance to the study medications: ASA, clopidogrel, coumadin and its derivatives
| 1
|
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NCT00948285
|
15:28:cancer,,,
|
Patients with breast cancer diagnosis during pregnancy (women who could bear children must have a negative pregnancy test before beginning this study)
| 1
|
[
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NCT02542657
|
1:10:treatment,21:24:chronic_disease,36:52:treatment,
|
Treatment sensitive HIV and, if on anti-HIV therapy, HIV viral load < 50 copies/mm^3
| 1
|
[
"Treatment",
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"HIV",
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"if",
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"HIV",
"viral",
"load",
"<",
"50",
"copies/mm^3"
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NCT01817751
|
1:24:chronic_disease,51:72:chronic_disease,74:98:chronic_disease,110:136:chronic_disease,,161:176:treatment
|
Arterial thromboembolic or embolic events such as myocardial infarction, cerebrovascular accident, including transient ischemic attacks 6 months prior to first study treatment
| 1
|
[
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1
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NCT02047474
|
36:46:cancer
|
There is no evidence of the second malignancy at the time of study entry
| 1
|
[
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NCT01293214
|
10:20:treatment
|
Level of amputation anywhere from the wrist (or ankle) joint to just below the shoulder (or hip) joint, which should be functional
| 1
|
[
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NCT02261519
|
49:72:chronic_disease,74:95:chronic_disease,97:113:chronic_disease,115:140:chronic_disease,142:166:chronic_disease,168:193:chronic_disease,195:212:chronic_disease,214:258:chronic_disease,260:268:chronic_disease,292:308:chronic_disease
|
Meets the DSM-IV or V criteria at screening for intellectual disability, dissociative disorder, bipolar disorder, major depressive disorder, schizoaffective disorder, schizophreniform disorder, autistic disorder, primary substance-induced psychotic disorder, dementia, or any other comorbid mental disorders that in the opinion of the Investigator may interfere with study conduct and results interpretation
| 1
|
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NCT02995330
|
1:19:treatment,21:30:treatment,32:43:treatment,49:83:cancer
|
Prior chemotherapy (docetaxel, cabazitaxel) for castrate resistant prostate cancer
| 1
|
[
"Prior",
"chemotherapy",
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"docetaxel",
",",
"cabazitaxel",
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[
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3,
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NCT02232165
|
38:52:allergy_name
|
Allergy or other contraindication to norepinephrine
| 1
|
[
"Allergy",
"or",
"other",
"contraindication",
"to",
"norepinephrine"
] |
[
0,
0,
0,
0,
0,
4
] |
NCT02407028
|
39:46:chronic_disease
|
Coma suspected to de due to primarily non-TBI causes
| 1
|
[
"Coma",
"suspected",
"to",
"de",
"due",
"to",
"primarily",
"non-TBI",
"causes"
] |
[
0,
0,
0,
0,
0,
0,
0,
2,
0
] |
NCT02227199
|
1:25:chronic_disease
|
congestive heart failure
| 1
|
[
"congestive",
"heart",
"failure"
] |
[
2,
2,
2
] |
NCT02129348
|
1:27:chronic_disease,
|
glomerular filtration rate less than 44ml/min/ 1.73m2
| 1
|
[
"glomerular",
"filtration",
"rate",
"less",
"than",
"44ml/min/",
"1.73m2"
] |
[
2,
2,
2,
0,
0,
0,
0
] |
NCT02507687
|
1:12:treatment,24:40:treatment,49:66:treatment,
|
Eye surgery (including cataract surgery) and or eye laser surgery within the past 6 months
| 1
|
[
"Eye",
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"eye",
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"surgery",
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"6",
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[
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0,
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0,
0
] |
NCT03179397
|
10:25:treatment
|
Previous corneal surgery
| 1
|
[
"Previous",
"corneal",
"surgery"
] |
[
0,
1,
1
] |
NCT01791543
|
7:34:treatment,63:84:chronic_disease,86:94:chronic_disease
|
prior antiarrhythmic drug therapy has failed due to recurrent ventricular arrythmia, toxicity, or intolerance
| 1
|
[
"prior",
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"drug",
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0,
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0,
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0,
2,
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2,
0,
0,
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] |
NCT03001882
|
46:64:chronic_disease
|
Participants with active, known or suspected autoimmune disease
| 1
|
[
"Participants",
"with",
"active",
",",
"known",
"or",
"suspected",
"autoimmune",
"disease"
] |
[
0,
0,
0,
0,
0,
0,
0,
2,
2
] |
NCT03062462
|
1:43:chronic_disease
|
severe congestive heart failure NYHA II-IV
| 1
|
[
"severe",
"congestive",
"heart",
"failure",
"NYHA",
"II-IV"
] |
[
2,
2,
2,
2,
2,
2
] |
NCT02805504
|
12:23:allergy_name
|
Allergy to bupivacaine
| 1
|
[
"Allergy",
"to",
"bupivacaine"
] |
[
0,
0,
4
] |
NCT02219555
|
1:12:chronic_disease
|
sarcoidosis
| 1
|
[
"sarcoidosis"
] |
[
2
] |
NCT02473250
|
1:14:chronic_disease
|
renal failure
| 1
|
[
"renal",
"failure"
] |
[
2,
2
] |
NCT02593123
|
1:33:cancer
|
Acute myelogenous leukemia (AML)
| 1
|
[
"Acute",
"myelogenous",
"leukemia",
"(",
"AML",
")"
] |
[
3,
3,
3,
3,
0,
0
] |
NCT02408861
|
40:51:cancer,120:129:treatment,139:147:cancer,149:157:cancer,163:208:cancer
|
For participants in the 24 participant solid tumor cohort, only those histologies not known to respond to single agent nivolumab (such as pancreas, prostate, and microsatellite stable [MSS] colorectal cancer)
| 1
|
[
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3,
0,
0,
0
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NCT02522715
|
1:10:treatment
|
Flutamide; approximate half-life: 6 hours; washout period required: 36 hours
| 1
|
[
"Flutamide",
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"washout",
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[
1,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT01050855
|
8:32:cancer
|
severe Langerhans histiocytosis
| 1
|
[
"severe",
"Langerhans",
"histiocytosis"
] |
[
0,
3,
3
] |
NCT02140255
|
24:28:treatment,
|
Mother did not receive ARVs during the current pregnancy per criteria above
| 1
|
[
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[
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0
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NCT01572480
|
,59:62:cancer,,,
|
Progressive increase in M protein level (evolving type of SMM; increase in serum M protein by greater than or equal to 25% on 2 successive evaluations within a 6-month period)
| 1
|
[
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NCT02101736
|
1:39:treatment,94:113:chronic_disease,203:217:treatment
|
Concomitant treatment with medications that prolong the QT interval and have a known risk of Torsades de Pointes is not contraindicated, but should be avoided if possible and will require more frequent EKG monitoring
| 1
|
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NCT02070549
|
5:18:treatment,30:42:treatment,44:56:treatment,44:78:treatment,80:96:treatment,101:114:treatment,,
|
Any major surgery, extensive radiotherapy, chemotherapy with delayed toxicity, biologic therapy, or immunotherapy within 28 days prior to enrollment and/or daily or weekly chemotherapy without the potential for delayed toxicity within 14 days prior to enrollment
| 1
|
[
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NCT02546583
|
,,46:56:treatment
|
Study Visit 1 loop diuretic dose ≤ 160 mg of furosemide equivalents
| 1
|
[
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"loop",
"diuretic",
"dose",
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[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0
] |
NCT02570672
|
11:21:chronic_disease,,
|
Untreated depression or Geriatric Depression Scale score on 15-item scale >7
| 1
|
[
"Untreated",
"depression",
"or",
"Geriatric",
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"Scale",
"score",
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[
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02414269
|
1:14:cancer,15:25:cancer,95:102:treatment
|
Breast cancer metastatic to the pleura that extends outside of the pleura requiring immediate therapy
| 1
|
[
"Breast",
"cancer",
"metastatic",
"to",
"the",
"pleura",
"that",
"extends",
"outside",
"of",
"the",
"pleura",
"requiring",
"immediate",
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[
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1
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NCT03170453
|
1:23:chronic_disease
|
Organic brain syndrome
| 1
|
[
"Organic",
"brain",
"syndrome"
] |
[
2,
2,
2
] |
NCT00467987
|
5:23:cancer
|
h/o prostate carcinoma
| 1
|
[
"h/o",
"prostate",
"carcinoma"
] |
[
0,
3,
3
] |
NCT02250157
|
,,,,187:189:treatment
|
Sexually active male subjects must use a barrier method of contraception during the study and agree to continue the use of male contraception for at least 30 days after the last dose of IP
| 1
|
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NCT02213289
|
28:38:cancer
|
No currently active second malignancy
| 1
|
[
"No",
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"second",
"malignancy"
] |
[
0,
0,
0,
0,
3
] |
NCT02584647
|
32:37:cancer,41:76:cancer,78:109:cancer,
|
Examples of the latter include basal or squamous cell carcinoma of the skin, in-situ carcinoma of the cervix, and isolated elevation of prostate-specific antigen
| 1
|
[
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"in-situ",
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NCT02950337
|
12:28:chronic_disease
|
ongoing or active infection
| 1
|
[
"ongoing",
"or",
"active",
"infection"
] |
[
0,
0,
2,
2
] |
NCT02578641
|
1:4:chronic_disease
|
HIV Positive
| 1
|
[
"HIV",
"Positive"
] |
[
2,
0
] |
NCT02303977
|
1:21:treatment,38:67:treatment,77:88:treatment,92:101:treatment,173:183:treatment,185:194:treatment,196:207:treatment,209:220:treatment,222:232:treatment,237:246:treatment
|
First-line treatment with a standard platinum doublet chemotherapy regimen (carboplatin or cisplatin at standard dosing plus one of the following drugs at standard dosing: paclitaxel, docetaxel, vinblastine, vinorelbine, pemetrexed, or etoposide)
| 1
|
[
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",",
"docetaxel",
",",
"vinblastine",
",",
"vinorelbine",
",",
"pemetrexed",
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1,
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1,
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0
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NCT02592551
|
,,,,,,,,,,,,,,,,,,334:350:cancer
|
Hemoglobin ≥ 9.0 g/dL Absolute neutrophil count (ANC) ≥ 1.5 × 109/L (> 1500 per mm3) Platelet count ≥ 100 × 109/L (>100,000 per mm3) Serum bilirubin ≤ 1.5× institutional upper limit of normal (ULN)AST<3.0 Creatinine clearance >50mL/miN Aspartate transaminase (AST) and alanine transaminase (ALT) ≤ 2.5 × ULN (≤ 5 × ULN if documented liver metastasis are present)
| 1
|
[
"Hemoglobin",
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NCT02471430
|
12:73:treatment
|
History of solid organ transplantation with an existing functional graft
| 1
|
[
"History",
"of",
"solid",
"organ",
"transplantation",
"with",
"an",
"existing",
"functional",
"graft"
] |
[
0,
0,
1,
1,
1,
1,
1,
1,
1,
1
] |
NCT02442102
|
1:29:treatment,37:47:treatment,49:60:treatment
|
Prior major thoracic surgery (e.g., sternotomy, thoracotomy)
| 1
|
[
"Prior",
"major",
"thoracic",
"surgery",
"(",
"e.g.",
",",
"sternotomy",
",",
"thoracotomy",
")"
] |
[
1,
1,
1,
1,
0,
0,
0,
1,
0,
1,
0
] |
NCT02857218
|
1:35:chronic_disease,57:91:treatment,136:164:treatment,170:181:treatment
|
Human immunodeficiency virus (HIV)-positive patients on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with ferumoxytol
| 1
|
[
"Human",
"immunodeficiency",
"virus",
"(",
"HIV",
")",
"-positive",
"patients",
"on",
"combination",
"antiretroviral",
"therapy",
"are",
"ineligible",
"because",
"of",
"the",
"potential",
"for",
"pharmacokinetic",
"interactions",
"with",
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] |
[
2,
2,
2,
2,
0,
0,
0,
0,
0,
1,
1,
1,
0,
0,
0,
0,
0,
0,
0,
1,
1,
0,
1
] |
NCT02313428
|
11:20:chronic_disease,32:37:chronic_disease,44:54:chronic_disease,58:71:chronic_disease
|
Untreated infection at site of ulcer (i.e. cellulitis or osteomyelitis)
| 1
|
[
"Untreated",
"infection",
"at",
"site",
"of",
"ulcer",
"(",
"i.e",
".",
"cellulitis",
"or",
"osteomyelitis",
")"
] |
[
0,
2,
0,
0,
0,
2,
0,
0,
0,
2,
0,
2,
0
] |
NCT02503722
|
13:29:chronic_disease
|
Significant valvular disease
| 1
|
[
"Significant",
"valvular",
"disease"
] |
[
0,
2,
2
] |
NCT02905370
|
1:17:chronic_disease
|
Terminal illness
| 1
|
[
"Terminal",
"illness"
] |
[
2,
2
] |
NCT01643473
|
6:31:chronic_disease,,,,,144:152:chronic_disease,156:170:chronic_disease,,,,227:230:chronic_disease,253:267:chronic_disease
|
Have uncontrolled hypertension defined as BP>140/90 mmHg on at least two consecutive visits in the past year (or BP>130/80 mmHg for those with diabetes or kidney disease) and Framingham Risk Scores (FRS) >20% (or at least one CVD risk factor including hyperlipidemia or diabetes)
| 1
|
[
"Have",
"uncontrolled",
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"BP",
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"140/90",
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"two",
"consecutive",
"visits",
"in",
"the",
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"(",
"or",
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"130/80",
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"kidney",
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")",
"and",
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"FRS",
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"or",
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0,
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0,
0,
2,
0,
0,
0
] |
NCT02094794
|
1:13:treatment,
|
Chemotherapy given within 14 days of planned study enrollment for the purpose of controlling counts is permitted
| 1
|
[
"Chemotherapy",
"given",
"within",
"14",
"days",
"of",
"planned",
"study",
"enrollment",
"for",
"the",
"purpose",
"of",
"controlling",
"counts",
"is",
"permitted"
] |
[
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02473250
|
1:11:cancer
|
malignancy
| 1
|
[
"malignancy"
] |
[
3
] |
NCT02433210
|
1:19:chronic_disease,56:63:chronic_disease,65:78:chronic_disease,80:89:chronic_disease
|
Medical conditions which may interfere with the study (cardiac, liver disease, Hepatitis)
| 1
|
[
"Medical",
"conditions",
"which",
"may",
"interfere",
"with",
"the",
"study",
"(",
"cardiac",
",",
"liver",
"disease",
",",
"Hepatitis",
")"
] |
[
2,
2,
0,
0,
0,
0,
0,
0,
0,
2,
0,
2,
2,
0,
2,
0
] |
NCT01597518
|
1:12:treatment
|
Montelukast
| 1
|
[
"Montelukast"
] |
[
1
] |
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