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NCT01850758
|
43:53:cancer,132:141:treatment,145:167:treatment
|
Tested positive or has been treated for a malignancy in the past or is suspected of having a malignancy or is currently undergoing radiation or chemotherapy treatment for a malignancy anywhere in the body, whether adjacent to or distant from the proposed injection site
| 1
|
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NCT01187368
|
51:68:treatment
|
Patients with an unacceptable risk for successful LVAD implantation and maintenance
| 1
|
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NCT01367444
|
34:54:chronic_disease,56:66:chronic_disease,68:81:chronic_disease,86:106:treatment
|
History or signs consistent with unilateral amblyopia (strabismic, anisometropic, or stimulus deprivation)
| 1
|
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NCT00432094
|
1:11:chronic_disease
|
arrhythmia
| 1
|
[
"arrhythmia"
] |
[
2
] |
NCT03120585
|
1:27:chronic_disease,31:63:chronic_disease,67:83:chronic_disease
|
Neonates with hypoglycemia or clinical evidence of dehydration or volume depletion requiring fluid bolus
| 1
|
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NCT02321501
|
1:19:chronic_disease,58:73:cancer,127:145:cancer
|
Measurable disease by RECIST or evaluable disease (e.g., bone metastasis, or lesions which do not fulfill RECIST criteria for metastatic disease)
| 1
|
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NCT00107289
|
1:5:treatment,11:13:cancer,39:48:treatment
|
MIBG-avid NB and evaluable disease on MIBG scan at time of enrollment on protocol
| 1
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NCT02841956
|
13:22:chronic_disease,
|
Duration of psychosis > 2 years
| 1
|
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NCT03110354
|
,,,141:177:treatment
|
Has prolonged corrected QT interval by Fridericia's method (QTcF) at rest, where the mean QTcF interval is > 450 milliseconds (ms) based on triplicate electrocardiograms (ECGs)
| 1
|
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NCT03097588
|
48:71:treatment
|
Subjects who have concurrent illness requiring systemic corticosteroid use
| 1
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NCT00911560
|
1:23:chronic_disease,
|
bone marrow metastases plus high urine catecholamine levels
| 1
|
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NCT01903330
|
13:45:cancer
|
presence of punctate hemorrhage in the tumor
| 1
|
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NCT02945800
|
12:28:chronic_disease
|
ongoing or active infection
| 1
|
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0,
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NCT01954576
|
50:53:cancer,70:91:treatment,182:188:treatment,192:201:treatment
|
Unequivocal evidence of recurrent or progressive GBM before or after bevacizumab treatment first based on radiographic appearances then confirmed by histologic confirmation through biopsy or resection
| 1
|
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NCT02245841
|
1:30:chronic_disease
|
juvenile dermatomyositis (JD)
| 1
|
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NCT02233868
|
20:38:treatment
|
Urine positive for psychoactive drugs (clinical laboratory results) on study days involving imaging (PET and MRI) and neuropsychological testing
| 1
|
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NCT02337465
|
1:38:chronic_disease
|
psychiatric illness/social situations that would limit compliance with study requirements
| 1
|
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NCT02706288
|
46:60:treatment
|
increase the risk of study procedures (e.g., anticoagulants) and that cannot be temporarily discontinued for this study
| 1
|
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NCT02419495
|
,16:29:treatment,52:61:treatment,69:76:treatment
|
> 4 weeks from prior therapy completion (including radiation and/or surgery)
| 1
|
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NCT02099591
|
49:61:treatment
|
Patients currently receiving the first cycle of chemotherapy
| 1
|
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NCT02501473
|
73:86:treatment
|
For patients enrolled in Part 2 or Part 4 with the potential to receive pembrolizumab
| 1
|
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NCT02341235
|
10:23:cancer,
|
Report a breast cancer diagnosis no more than 10 years prior to enrollmen
| 1
|
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NCT02585973
|
47:74:treatment,57:74:treatment
|
Unable or unwilling to discontinue use of any sensitive CYP3A4 substrates and CYP3A4 substrates with a narrow therapeutic window
| 1
|
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NCT02752191
|
38:56:treatment
|
other causes (for subjects receiving Feraheme injection only)
| 1
|
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NCT01865162
|
12:40:chronic_disease
|
History of human immunodeficiency virus
| 1
|
[
"History",
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"virus"
] |
[
0,
0,
2,
2,
2
] |
NCT00632853
|
1:13:treatment
|
chemotherapy
| 1
|
[
"chemotherapy"
] |
[
1
] |
NCT01366612
|
34:44:cancer,
|
Diagnosed or treated for another malignancy within 3 years of enrollment
| 1
|
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NCT00392756
|
117:129:treatment
|
with a single serum sample demonstrating low estradiol (estrogen) in association with low or inappropriately normal gonadotropin levels
| 1
|
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NCT01849146
|
,16:40:treatment
|
6 weeks from a nitrosourea chemotherapy
| 1
|
[
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NCT02200445
|
25:46:chronic_disease
|
Positive stool test for Clostridium difficile
| 1
|
[
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"difficile"
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[
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0,
0,
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2
] |
NCT01415752
|
36:62:cancer,93:119:treatment,155:196:treatment
|
Histologically confirmed untreated mantle cell lymphoma (MCL), with documented cyclin D1 by immunohistochemical stains and/or t(11;14) by cytogenetics or fluorescence in situ hybridization (FISH)
| 1
|
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NCT00887146
|
35:42:cancer
|
Patients with codeleted low grade gliomas must also be considered high risk by exhibiting one or more of the following characteristics
| 1
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NCT02386605
|
1:22:chronic_disease
|
Neurological disorder
| 1
|
[
"Neurological",
"disorder"
] |
[
2,
2
] |
NCT03151330
|
,50:68:chronic_disease
|
The subject has known elevated bilirubin levels (hyperbilirubinemia)
| 1
|
[
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NCT03068442
|
7:20:cancer,31:49:chronic_disease,53:64:cancer
|
Known stroke mimics including multiple sclerosis or brain tumor
| 1
|
[
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[
0,
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2,
0,
3,
3
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NCT03096418
|
,40:53:cancer
|
Women with pathologically demonstrated breast cancer
| 1
|
[
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"breast",
"cancer"
] |
[
0,
0,
0,
0,
3,
3
] |
NCT01928576
|
31:49:chronic_disease
|
Any active history of a known autoimmune disease
| 1
|
[
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"autoimmune",
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] |
[
0,
0,
0,
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0,
0,
2,
2
] |
NCT02551679
|
9:33:treatment
|
Chronic cytotoxic drug treatment
| 1
|
[
"Chronic",
"cytotoxic",
"drug",
"treatment"
] |
[
0,
1,
1,
1
] |
NCT02964039
|
14:22:chronic_disease
|
Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
| 1
|
[
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"weight",
"loss",
",",
"diabetic",
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NCT02495753
|
,19:49:chronic_disease
|
women with active herpes simplex virus infection
| 1
|
[
"women",
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[
0,
0,
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2,
2,
2,
2
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NCT02438995
|
,25:48:treatment
|
Less than 6 months from prior Radiation Therapy (Arm 1)
| 1
|
[
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NCT02250157
|
28:55:treatment
|
Require therapeutic use of anticoagulation medications
| 1
|
[
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[
0,
0,
0,
0,
1,
1
] |
NCT02423863
|
26:40:treatment
|
Persistent toxicity from recent therapy that has not sufficiently resolved in the judgment of the study physician
| 1
|
[
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NCT02423863
|
,,,,128:143:treatment
|
Transaminases ≤ 2 times above the upper limits of the institutional normal, - INR<2 (international normalized ratio) if off of anticoagulation
| 1
|
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NCT02583893
|
1:11:treatment,18:25:treatment,43:54:treatment,56:68:treatment,70:82:treatment,84:96:treatment,102:114:treatment,
|
Tacrolimus (e.g. Prograf) Subjects taking fluconozole, voriconizole, itraconazole, posaconazole, and ketokonazole within 72 hours of study drug starting
| 1
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NCT02072148
|
21:59:treatment,
|
Participation in an investigational therapeutic drug trial within 30 days of study entry
| 1
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NCT01591356
|
34:55:chronic_disease,106:123:chronic_disease,125:137:chronic_disease,142:147:cancer
|
Patients with active bleeding or pathologic conditions that carry high risk of bleeding, such as a known bleeding disorder, coagulopathy, or tumor involving major vessels
| 1
|
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NCT00719888
|
,,97:109:treatment
|
ligible with (M2 marrow) with =< 25% blasts in marrow after having failed one or more cycles of chemotherapy
| 1
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NCT01543490
|
10:24:treatment,
|
Have had eyelid surgery in the study eye within twelve (12) months prior to Visit 1 or plan to have eyelid surgery during the study
| 1
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NCT02127398
|
1:12:treatment
|
gastrostomy
| 1
|
[
"gastrostomy"
] |
[
1
] |
NCT02918175
|
1:22:chronic_disease,9:22:chronic_disease,,,,84:93:treatment,99:110:treatment,
|
Chronic heart failure, New York Heart Association (NYHA) class II-IV, with ongoing treatment with medications for heart failure for at least 1 month prior to enrollment
| 1
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NCT02808442
|
1:45:cancer
|
Active Central Nervous System (CNS) leukemia
| 1
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NCT02231073
|
1:13:chronic_disease,24:56:chronic_disease,65:95:chronic_disease,97:120:chronic_disease,122:143:chronic_disease,148:165:chronic_disease
|
Parkinsonism subjects: iPD and Parkinson plus syndromes such as Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Syndrome, or Cerebellar Ataxia
| 1
|
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NCT02466126
|
30:43:treatment
|
Veterans currently receiving psychotherapy WILL be excluded
| 1
|
[
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0,
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0,
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NCT02099058
|
26:45:treatment
|
Subjects enrolled on the combination therapy phase must satisfy the above exclusion criteria
| 1
|
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NCT03107520
|
7:35:chronic_disease
|
Known heart or pulmonary condition
| 1
|
[
"Known",
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] |
[
0,
2,
2,
2,
2
] |
NCT02857218
|
12:28:chronic_disease
|
ongoing or active infection
| 1
|
[
"ongoing",
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"infection"
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[
0,
0,
2,
2
] |
NCT02130687
|
1:44:treatment,
|
Treatment with antihypertensive medications for a minimum of 6 months
| 1
|
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] |
NCT03038620
|
1:8:treatment
|
Surgery scheduled for the trial duration period
| 1
|
[
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[
1,
0,
0,
0,
0,
0,
0
] |
NCT01445821
|
1:4:chronic_disease
|
HIV positive
| 1
|
[
"HIV",
"positive"
] |
[
2,
0
] |
NCT03112603
|
52:64:chronic_disease
|
Participants with clinically diagnosed moderate to severe cGvHD according to NIH Consensus Criteria prior to randomization
| 1
|
[
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NCT02869789
|
27:45:chronic_disease
|
ctive, known or suspected autoimmune disease
| 1
|
[
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[
0,
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2
] |
NCT03073629
|
12:37:chronic_disease,41:55:chronic_disease,73:89:treatment
|
those with indeterminate RV function OR LV dysfunction on comprehensive echocardiography
| 1
|
[
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NCT01059786
|
35:46:treatment,47:54:treatment,,112:127:treatment
|
The patient may have any required vaccination/booster administered at least 4 weeks prior to the initiation of study treatment
| 1
|
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NCT02013154
|
1:10:treatment,16:31:treatment,,84:108:treatment,
|
Treatment with corticosteroids (≥ 10 mg per day prednisone or equivalent) or other immune suppressive drugs within the 14 days prior to study entry
| 1
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NCT03101956
|
1:35:chronic_disease
|
Nervous system disease or disorder
| 1
|
[
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] |
[
2,
2,
2,
2,
2
] |
NCT03171493
|
,,98:107:treatment
|
Men or women of childbearing potential who are unwilling to employ adequate contraception during treatment and 8 weeks following the completion of study drug treatment
| 1
|
[
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NCT01494662
|
4:32:treatment
|
No prior therapy with neratinib
| 1
|
[
"No",
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] |
[
0,
1,
1,
1,
1
] |
NCT02232516
|
,,69:71:treatment
|
Patients must have bi-dimensionally measurable disease (>= 1 cm) by CT imaging
| 1
|
[
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NCT02488057
|
1:9:chronic_disease
|
diabetic
| 1
|
[
"diabetic"
] |
[
2
] |
NCT02013154
|
7:35:cancer
|
Known osteoblastic bony metastasis
| 1
|
[
"Known",
"osteoblastic",
"bony",
"metastasis"
] |
[
0,
3,
3,
3
] |
NCT01943851
|
23:45:chronic_disease
|
Evidence of severe of uncontrolled infection
| 1
|
[
"Evidence",
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"of",
"uncontrolled",
"infection"
] |
[
0,
0,
0,
0,
2,
2
] |
NCT01988246
|
1:70:treatment,
|
Intravitreal anti-VEGF (vascular endothelial growth factor) treatment in the study eye within 6 months of the pre-operative baseline visit
| 1
|
[
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0
] |
NCT03131037
|
23:47:chronic_disease,57:72:chronic_disease,74:98:chronic_disease,112:156:chronic_disease
|
Presence of any other life-threatening illness, such as unstable angina, severe oxygen dependence, significant chronic obstructive pulmonary disease (COPD)
| 1
|
[
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NCT02852057
|
1:12:chronic_disease
|
Bradycardia
| 1
|
[
"Bradycardia"
] |
[
2
] |
NCT02301611
|
12:32:treatment,64:76:treatment,78:95:treatment
|
Completing SoC adjuvant therapy per NCCN guidelines to include chemotherapy, radiation therapy
| 1
|
[
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1,
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NCT02907944
|
108:117:treatment
|
Meets criteria for lifetime or current tobacco, alcohol and/or opioid use disorder regardless of addiction treatment status
| 1
|
[
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NCT01532687
|
3:15:treatment
|
A hysterectomy
| 1
|
[
"A",
"hysterectomy"
] |
[
0,
1
] |
NCT03082612
|
46:58:treatment
|
Treatment plans to include weekly outpatient chemotherapy
| 1
|
[
"Treatment",
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"outpatient",
"chemotherapy"
] |
[
0,
0,
0,
0,
0,
0,
1
] |
NCT02091999
|
18:37:chronic_disease,39:44:cancer,49:52:treatment
|
Dose Escalation, Renal insufficiency, NSCLC and CPI-Treated Expansion Cohorts
| 1
|
[
"Dose",
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"Renal",
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[
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3,
0,
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0,
0
] |
NCT02352480
|
22:30:treatment,
|
Subject has received UCC care for ≥ 2 weeks at treating wound clinic
| 1
|
[
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0,
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0,
0,
0,
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NCT01791543
|
10:46:chronic_disease,50:79:treatment,85:96:treatment
|
Definite protruding left ventricular thrombus on pre-ablation echocardiography when LV ablation is required
| 1
|
[
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0,
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] |
NCT02091141
|
1:19:treatment,25:36:treatment,50:64:treatment,66:81:treatment
|
Previous treatment with vemurafenib or any other BRAF inhibitor (prior sorafenib is allowed)
| 1
|
[
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NCT02347995
|
38:46:chronic_disease,,,,
|
untreated and / or poorly controlled diabetes with fasting blood glucose of greater than 170 and HbA1c greater than 10.0
| 1
|
[
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0
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NCT02690116
|
14:21:chronic_disease,,
|
Experiencing fatigue (scoring < 75 on Vitality scale of Short Form (SF)-36)
| 1
|
[
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NCT02946892
|
1:18:chronic_disease,,
|
Renal dysfunction defined as serum creatinine >2.0mg/dL
| 1
|
[
"Renal",
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[
2,
2,
0,
0,
0,
0,
0,
0
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NCT02562430
|
53:61:allergy_name
|
History of inadequate response/poor tolerability to bupropio
| 1
|
[
"History",
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"inadequate",
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"bupropio"
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[
0,
0,
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0,
0,
0,
4
] |
NCT01421810
|
23:31:chronic_disease,,,,
|
Previous diagnosis of diabetes, fasting glucose ≥126 mg/dL, or a hemoglobin A1c >6.5%
| 1
|
[
"Previous",
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"of",
"diabetes",
",",
"fasting",
"glucose",
"≥126",
"mg/dL",
",",
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NCT02369406
|
1:4:chronic_disease,,
|
HIV-positive between 96 hours and 42 days after birth
| 1
|
[
"HIV-positive",
"between",
"96",
"hours",
"and",
"42",
"days",
"after",
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[
2,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT01943851
|
67:77:treatment
|
This method must be used from the time of the first dose of study medication until 16 weeks after the last dose of study medication
| 1
|
[
"This",
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NCT02101853
|
1:18:treatment,11:18:treatment,,61:78:treatment,101:112:chronic_disease,,191:215:treatment,220:244:treatment,246:258:treatment
|
Cytotoxic therapy: at least 14 days since the completion of cytotoxic therapy with the exception of hydroxyurea, which is permitted up to 24 hours prior to the start of protocol therapy, or maintenance chemotherapy, or intrathecal chemotherapy (methotrexate strongly preferred) administered at the time of the required diagnostic lumbar puncture to establish baseline CNS status
| 1
|
[
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NCT02271100
|
13:22:chronic_disease
|
Significant scoliosis
| 1
|
[
"Significant",
"scoliosis"
] |
[
0,
2
] |
NCT02784535
|
60:82:treatment,84:105:treatment,107:128:treatment,130:154:treatment,156:177:treatment
|
Use of other norepinephrine transporter inhibitors such as Wellbutrin (Bupropion), Cymbalta (Duloxetine), Effexor (venlafaxine), Pristiq (desvenlafaxine), Savella (milnacipran)
| 1
|
[
"Use",
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"other",
"norepinephrine",
"transporter",
"inhibitors",
"such",
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"Wellbutrin",
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"Bupropion",
")",
",",
"Cymbalta",
"(",
"Duloxetine",
")",
",",
"Effexor",
"(",
"venlafaxine",
")",
",",
"Pristiq",
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"desvenlafaxine",
")",
",",
"Savella",
"(",
"milnacipran",
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0,
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1,
0,
0,
0,
1,
1,
0,
0,
0,
1,
1,
0,
0
] |
NCT02932410
|
6:38:chronic_disease
|
with pulmonary veno-occlusive disease
| 1
|
[
"with",
"pulmonary",
"veno-occlusive",
"disease"
] |
[
0,
2,
2,
2
] |
NCT01433315
|
54:86:chronic_disease
|
The investigators will exclude subjects who have any medical or psychiatric disorders
| 1
|
[
"The",
"investigators",
"will",
"exclude",
"subjects",
"who",
"have",
"any",
"medical",
"or",
"psychiatric",
"disorders"
] |
[
0,
0,
0,
0,
0,
0,
0,
0,
2,
2,
2,
2
] |
NCT02046330
|
35:44:treatment
|
Presence of a condition requiring diathermy
| 1
|
[
"Presence",
"of",
"a",
"condition",
"requiring",
"diathermy"
] |
[
0,
0,
0,
0,
0,
1
] |
NCT01614197
|
29:50:treatment,,
|
Patients must have been off blinatumomab infusion for at least 4 days and all drug-related toxicity must have resolved to grade 2 or lower as outlined in the inclusion and exclusion criteria
| 1
|
[
"Patients",
"must",
"have",
"been",
"off",
"blinatumomab",
"infusion",
"for",
"at",
"least",
"4",
"days",
"and",
"all",
"drug-related",
"toxicity",
"must",
"have",
"resolved",
"to",
"grade",
"2",
"or",
"lower",
"as",
"outlined",
"in",
"the",
"inclusion",
"and",
"exclusion",
"criteria"
] |
[
0,
0,
0,
0,
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0,
0,
0,
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0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
NCT02750319
|
13:25:chronic_disease
|
Patients in sinus rhythm
| 1
|
[
"Patients",
"in",
"sinus",
"rhythm"
] |
[
0,
0,
2,
2
] |
NCT02414269
|
1:45:treatment,52:65:treatment,67:81:treatment,85:100:treatment,,175:190:treatment
|
Prior immunotherapy with checkpoint blockade (i.e. PD1 inhibitor, PDL1 inhibitor or CTL4-antagonist or similar agent) must have been completed more than 1 month1prior to the T cell infusion
| 1
|
[
"Prior",
"immunotherapy",
"with",
"checkpoint",
"blockade",
"(",
"i.e",
".",
"PD1",
"inhibitor",
",",
"PDL1",
"inhibitor",
"or",
"CTL4-antagonist",
"or",
"similar",
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")",
"must",
"have",
"been",
"completed",
"more",
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"1",
"month1prior",
"to",
"the",
"T",
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[
1,
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1,
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0,
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0,
0,
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0,
0,
0,
0,
0,
0,
0,
1,
1,
1
] |
NCT02419495
|
1:13:treatment,18:31:treatment,45:72:treatment,,93:103:treatment,144:163:treatment,154:163:treatment,226:235:treatment,290:311:treatment,335:359:treatment
|
Chemotherapy, or immunotherapy or any other systemic anticancer therapy =< 3 weeks prior to study drug administration date; patients receiving anti-PD-1 treatment, and continue to receiving this treatment in combination with selinexor (Arms L and M), can start receiving the selinexor and anti-PD-1 combination without washout of the prior anti-PD-1 antibody
| 1
|
[
"Chemotherapy",
",",
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"any",
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"therapy",
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