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NCT01913106 | 13:31:cancer | Symptomatic metastasis disease | 2 | [
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NCT02176161 | 1:28:treatment | oral glucocorticoid therapy | 2 | [
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NCT02807272 | ,32:48:treatment | At least 1 week since the last systemic therapy regimen prior to Cycle 1 Day 1 | 2 | [
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NCT02535312 | 38:60:treatment | Patients who are receiving any other investigational agents | 2 | [
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NCT01697371 | 1:23:chronic_disease | Active liver infection | 2 | [
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NCT02836574 | 12:18:cancer, | history of cancer within the past 3 years | 2 | [
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NCT02148003 | 8:15:chronic_disease,, | morbid obesity (BMI > 35kg/m2) | 2 | [
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NCT02278315 | ,,97:109:treatment | 25% increase in bone marrow plasma cell percentage from lowest response value during (or after) last therapy | 2 | [
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NCT02635360 | 1:12:chronic_disease | Hepatitis C | 2 | [
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NCT02311361 | 1:18:cancer | Malignant ascites that is clinically detectable by physical examination or is symptomatic | 2 | [
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NCT02304458 | 24:60:cancer | Part D6: Patients with relapsed or refractory neuroblastoma (MIBG evaluable disease without RECIST measurable lesion) | 2 | [
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NCT02091999 | 104:129:cancer,131:152:cancer,157:185:cancer,,268:295:treatment | Subjects with recurrent disease or histologically or cytologically confirmed Stage III/IV diagnosis of epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal carcinoma who have previously progressed while receiving or within 6 months of completing a platinum-containing regimen | 2 | [
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NCT03105700 | 12:18:chronic_disease | History of stroke | 2 | [
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NCT02974686 | 21:31:allergy_name,33:42:allergy_name,53:75:allergy_name | Hypersensitivity to everolimus, sirolimus, or other rapamycin deriviatives | 2 | [
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NCT01430390 | 8:21:treatment,23:46:treatment,,74:82:treatment | Recent prior therapy: Systematic chemotherapy less than 2 weeks prior to infusion | 2 | [
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NCT00857207 | 12:42:chronic_disease | History of pre-morbid learning disability | 2 | [
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NCT02393742 | 20:45:chronic_disease,, | Moderate or severe peripheral artery disease (ankle-brachial index <0.7)(183) | 2 | [
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NCT02592551 | 23:26:cancer | Surgically resectable MPM with no disease extension beyond the ipsilateral hemithorax | 2 | [
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NCT02315196 | 47:65:cancer | Definitive clinical or radiologic evidence of metastatic disease | 2 | [
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NCT02366871 | 12:30:treatment | undergoing surgical debulking | 2 | [
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NCT02562716 | 16:34:cancer | No evidence of metastatic disease | 2 | [
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NCT02204098 | 7:25:chronic_disease | Known metastatic disease | 2 | [
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NCT02542657 | ,69:109:treatment | Disease that has progressed during or within 6 months of coming off therapy with bortezomib and lenalidomide (either sequentially or concurrent); progressive disease | 2 | [
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NCT02115295 | ,,,,,,133:153:cancer,,,,, | Adequate organ function as defined below: liver function (bilirubin </=2mg/dL, AST and/or ALT </=3 x ULN- or <5 x ULN if related to leukemic involvement), kidney function (creatinine </=1.5 x ULN ), known cardiac ejection fraction of > or = 45% within the past 6 months | 2 | [
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NCT02971202 | 1:20:chronic_disease | severe hypoglycemia | 2 | [
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NCT02496611 | 1:8:chronic_disease,25:41:chronic_disease,43:62:chronic_disease | Obesity associated with genetic disorder (monogenetic obesity) | 2 | [
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NCT03051347 | 42:56:chronic_disease | Any child with a potentially disfiguring skin condition or change in appearance related to disease/intervention will be considered eligible | 2 | [
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NCT03072238 | 1:33:treatment,56:72:treatment,80:92:treatment,94:103:treatment | Prior treatment with abiraterone or other known potent CYP17 inhibitors (e.g., ketoconazole, orteronel) or investigational agents that block androgen synthesis | 2 | [
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NCT02429934 | 22:40:chronic_disease, | Subjects with active glomerulonephritis (>3 g protein/24h and/or active urine sediment) | 2 | [
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NCT02555189 | 1:23:treatment,35:38:treatment,40:51:treatment,57:71:treatment,90:118:treatment | Hormonal-acting agents (including DES, aldosterone, and spironolactone but not including GnRH agonists or antagonists) are forbidden during the trial and must be stopped prior to enrollment. No washout period will be required for any of these agents | 2 | [
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NCT02091141 | 1:19:chronic_disease | Measurable disease by RECIST v1.1 | 2 | [
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NCT02076906 | 15:21:cancer,90:97:treatment,147:156:treatment | The patient's cancer must have relapsed after or failed to respond to frontline curative therapy and there must not be other potentially curative treatment options available | 2 | [
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NCT03058029 | 12:41:treatment | History of abdominal radiation treatment | 2 | [
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NCT02107703 | 24:42:cancer,117:126:treatment,142:154:treatment,161:180:treatment,184:212:treatment | presented de novo with metastatic disease and then relapsed with radiologic evidence of progression after receiving treatment with either an antiestrogen or an aromatase inhibitor as first line endocrine therapy for metastatic disease | 2 | [
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NCT02520791 | 24:40:treatment,48:65:treatment,69:85:treatment,91:138:treatment, | Patients not receiving systemic therapy (i.e., systemic steroids or biologic therapy with disease modifying anti-rheumatic drugs [DMARDs]) within 2 years | 2 | [
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NCT02624258 | 15:17:chronic_disease,36:54:treatment,72:86:treatment | subjects with HL with no available curative treatment options (such as autologous SCT) | 2 | [
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NCT02257424 | 48:72:cancer | Subjects with a history of completely resected non-melanoma skin cancer | 2 | [
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NCT02588612 | ,,,,89:114:chronic_disease | Corrected QT interval (QTc) >450 milliseconds (msec) or QTc >480 msec for subjects with Bundle Branch Block (BBB) | 2 | [
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NCT02171104 | 1:32:chronic_disease | Mucopolysaccharidosis Disorders | 2 | [
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NCT03103646 | 40:50:treatment | Subject has previously been dosed with Lu AF35700 | 2 | [
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NCT02310399 | 73:111:treatment | Loss or lack of benefit from appropriate CI without the possibility for revision or contralateral implantation | 2 | [
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NCT02516696 | 38:54:cancer | Subject has histologically confirmed multiple myeloma that has never before been treated | 2 | [
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NCT02760498 | 69:88:allergy_name | Allergic reactions or acute hypersensitivity reaction attributed to antibody treatments | 2 | [
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NCT02469519 | 26:29:chronic_disease | Received first course of ACS at or prior to 31w6d gestation | 2 | [
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NCT02503709 | ,,,,,112:137:treatment,166:183:chronic_disease,217:240:chronic_disease | Consistent corrected QT (QTc) > 450 msec for men and > 470 msec for women by Fridericia formula, on 3 separate electrocardiograms (ECGs); patients with a history of long QTc syndrome or personal or family history of ventricular arrhythmias will be excluded | 2 | [
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NCT02655614 | 126:135:treatment | For participants participating in a designated drug-drug interaction (DDI) cohort in the MAD stage of the study, who require midazolam/caffeine administration: known allergy, religious prohibition, or other condition limiting midazolam or caffeine administration | 2 | [
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NCT02541565 | 1:33:cancer,35:70:cancer,78:98:cancer,130:146:treatment | basal cell carcinoma of the skin, squamous cell carcinoma of the skin, or in situ cervical cancer that has undergone potentially curative therapy | 2 | [
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NCT01648751 | 87:92:chronic_disease,94:114:chronic_disease,116:127:chronic_disease,129:146:chronic_disease,148:163:chronic_disease,169:191:chronic_disease | Connective tissue diseases known to affect collagen or elastin remodeling (including: Lupus, Rheumatoid Arthritis, Scleroderma, Sjogrens syndrome, Marfan syndrome, and Ehlers-Danlos syndrome) | 2 | [
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NCT02819440 | 16:32:treatment,34:44:treatment,46:55:treatment,57:67:treatment | Current use of PDE-5 inhibitors (sildenafil, tadalafil, vardenafil) | 2 | [
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NCT02264236 | 34:56:chronic_disease,58:81:chronic_disease,85:101:cancer | Existing diagnosis or history of leptomeningeal disease, spinal cord compression or brain metastases unless | 2 | [
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NCT02429557 | 13:20:chronic_disease,22:27:chronic_disease,31:46:chronic_disease | Significant cardiac, renal or hepatic illness, or with contraindications to administration of pressor agents or external abdominal compression | 2 | [
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NCT02506192 | 27:37:treatment | Known hypersensitivity to Prednisone | 2 | [
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NCT02315196 | 1:20:treatment,56:62:treatment,,149:167:cancer | Computed tomography of the chest, abdomen, and pelvis (CT CAP) and bone scan performed within 30 days prior to study entry and does not demonstrate metastatic disease | 2 | [
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NCT02332668 | 1:57:treatment, | prior allogeneic hematopoietic stem cell transplantation within the last 5 years | 2 | [
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NCT00186927 | 23:26:chronic_disease | household member with URI | 2 | [
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NCT00967577 | 1:30:treatment,32:43:treatment,,74:83:treatment | Prior investigational therapy (medications or devices) within 6 weeks of treatment | 2 | [
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NCT00716066 | 1:22:chronic_disease | Stiff Person Syndrome | 2 | [
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NCT02166190 | 1:18:cancer,22:40:cancer,56:74:treatment | Pancreatic cancer or cholangiocarcinoma unsuitable for surgical resection | 2 | [
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NCT01614197 | 1:19:treatment,82:89:treatment,97:115:treatment,117:134:treatment,138:151:treatment | Anti-cancer Agents: Patients who are currently receiving or may receive while on therapy, other anti-cancer agents, radiation therapy or immunotherapy are not eligible | 2 | [
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NCT03038620 | 12:37:chronic_disease, | History of Major Depressive Disorder within the last 2 years | 2 | [
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NCT02261519 | 40:53:chronic_disease,,196:209:chronic_disease,214:233:chronic_disease | Physician confirmed DSM-V diagnosis of schizophrenia for the past 2 years based on subject's history and confirmed by psychiatric evaluation and MINI International Neuropsychiatric Interview For Schizophrenia and Psychotic Disorders, version 7.0 (MINI, Version 7.0) | 2 | [
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