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NCT02576444
|
72:88:chronic_disease,90:120:chronic_disease,124:130:chronic_disease,132:154:chronic_disease,211:233:chronic_disease,235:262:chronic_disease,274:296:chronic_disease,300:309:treatment,317:337:chronic_disease
|
Patients considered a poor medical risk due to a serious, uncontrolled medical disorder, non-malignant systemic disease or active, uncontrolled infection. Examples include, but are not limited to, uncontrolled ventricular arrhythmia, superior vena cava syndrome, extensive bilateral lung disease on HRCT scan or any psychiatric disorder that prohibits obtaining informed consent
| 1
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NCT02390752
|
1:21:cancer
|
Optic pathway glioma are located in the optic pathway and are typically hypo- or iso-intense on T1 and hyperintense on T2-weighted images
| 1
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NCT02122081
|
8:19:chronic_disease
|
Active CNS disease as identified by positive CSF cytospin at time of enrollment
| 1
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NCT02811263
|
45:63:treatment,77:105:treatment,116:128:treatment,130:146:treatment,151:155:treatment
|
Need for resuscitation at 10 minutes (i.e., chest compressions, or positive pressure respiratory support including endotracheal, mask ventilation, or CPAP)
| 1
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NCT02581384
|
1:33:treatment
|
focal radiotherapy to the thorax
| 1
|
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NCT03148379
|
1:23:chronic_disease
|
inflammatory arthritis
| 1
|
[
"inflammatory",
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] |
[
2,
2
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NCT02587312
|
30:39:treatment,
|
Participants who are seeking treatment for their smoking or who report that they intend to quit smoking within the next 30 days and have made a 24-hour quit attempt in the past year
| 1
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NCT01905046
|
31:44:cancer
|
Must be at increased risk for breast cancer
| 1
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NCT01973283
|
,,41:49:chronic_disease
|
Mini Mental Exam < 24 or a diagnosis of dementia
| 1
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NCT01726257
|
1:36:chronic_disease
|
Proximal non-aneurysmal aortic neck
| 1
|
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"aortic",
"neck"
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[
2,
2,
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NCT00293475
|
1:20:treatment
|
spinal radiotherapy
| 1
|
[
"spinal",
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[
1,
1
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NCT01804634
|
58:67:treatment
|
Patients must be willing to participate in all stages of treatment
| 1
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NCT02361554
|
12:34:chronic_disease,,,92:104:chronic_disease,105:113:chronic_disease,114:131:chronic_disease
|
history of traumatic brain injury associated with loss of consciousness of > 1 hour and/or intracranial/epidural/subdural bleeding
| 1
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NCT02075671
|
28:42:chronic_disease
|
Any history or evidence of severe illness or any other condition that would make the patient, in the opinion of the investigator, unsuitable for the study
| 1
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NCT03123783
|
28:46:chronic_disease
|
Active, known or suspected autoimmune disease
| 1
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NCT03104699
|
32:45:treatment,,
|
Persisting toxicity related to prior therapy of NCI CTCAE grade >1 severity
| 1
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NCT02519946
|
1:17:treatment,
|
Heart transplant >11 months before baseline visit
| 1
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NCT02013154
|
57:78:cancer,82:108:cancer,109:122:cancer,126:140:cancer,144:166:cancer
|
Participants with histologically confirmed recurrent or metastatic esophageal or gastro-esophageal junction squamous cell or adenocarcinoma or gastric adenocarcinoma with Wnt Signaling Alterations
| 1
|
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NCT02543983
|
1:33:treatment,
|
Treatment with a reversible MAOI within 2 weeks prior to study Phase III
| 1
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NCT01989585
|
18:41:chronic_disease,37:40:chronic_disease,46:69:chronic_disease,65:68:chronic_disease
|
Known history of hepatitis B virus (HBV), or hepatitis C virus (HCV) infection (patients with chronic or cleared HBV and HCV infection are eligible); it is not necessary to conduct HBV and HCV testing at screening
| 1
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NCT02312570
|
,88:97:treatment
|
Greater than 30% reduction in wound size during the first two weeks of observation and treatment by the investigator
| 1
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NCT03042689
|
1:16:chronic_disease
|
Unstable angina (anginal symptoms at rest)
| 1
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NCT02366754
|
6:9:treatment,13:16:treatment,54:68:chronic_disease
|
Have MRI or TMS contraindications such as pre-injury claustrophobia, metal in eyes/face or brain
| 1
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NCT02089607
|
39:55:treatment
|
The two vessels incorporated into the endograft repair would most commonly be the innominate artery and left common carotid artery
| 1
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NCT02567422
|
12:28:chronic_disease,39:62:treatment,78:87:treatment
|
Ongoing or active infection requiring intravenous antibiotics at the time of treatment initiation
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NCT01822522
|
28:41:chronic_disease,28:31:chronic_disease,101:142:treatment,144:165:treatment,359:387:treatment
|
Serologic documentation of HIV infection at any time prior to study entry, as evidenced by positive enzyme-linked immunosorbent assay (ELISA), positive western blot, or any other federally approved licensed HIV test; alternatively, this documentation may include a record that another physician has documented that the participant has HIV infection based on prior ELISA and western blot, or other approved diagnostic tests
| 1
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NCT02181257
|
15:34:chronic_disease,36:59:chronic_disease,61:90:chronic_disease,92:111:chronic_disease,113:134:chronic_disease,136:144:chronic_disease,155:167:chronic_disease,171:187:chronic_disease,220:231:treatment
|
patients with lupus erythematosus, porphyria cutanea tarda, erythropoietic protoporphyria, variegate porphyria, xeroderma pigmentosum, albinism, or other dermatologic or ocular condition that contraindicates the use of methoxsalen or markedly enhances photosensitivity in the investigator's judgment
| 1
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NCT02977468
|
23:48:cancer,87:104:treatment,106:127:treatment,132:145:treatment,149:152:treatment,157:161:treatment
|
Histologically proven invasive breast carcinoma with triple negative receptor status (Estrogen receptor, Progesterone receptor and HER2 negative by IHC and FISH)
| 1
|
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NCT02799095
|
41:75:chronic_disease
|
The subject is known to be positive for human immunodeficiency virus (HIV)
| 1
|
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NCT02600273
|
10:13:chronic_disease
|
Unstable HIV or associated comorbidities, as determined by a licensed medical professional
| 1
|
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NCT02237183
|
131:139:allergy_name
|
Participants must not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition of iloprost
| 1
|
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0,
4
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NCT02148263
|
8:24:chronic_disease
|
Active ocular infection
| 1
|
[
"Active",
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0,
2,
2
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NCT02496208
|
26:63:treatment,32:41:treatment,,,219:281:treatment
|
The subject has received prior treatment with hormonal therapy within 14 days or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment; subjects receiving gonadotropin-releasing hormone (GnRH) agonists and antagonists are allowed to participate
| 1
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NCT02967315
|
15:85:chronic_disease
|
patients with anomalous coronary crossing the right ventricular outflow tract (RVOT)
| 1
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NCT02990481
|
16:33:treatment,35:42:treatment,44:56:treatment,61:84:treatment,
|
Treatment with radiation therapy, surgery, chemotherapy, or investigational therapy within four weeks prior to study entry
| 1
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NCT02836899
|
1:35:treatment,,
|
Elective cardiac or aortic surgery with CPB>90 minutes
| 1
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NCT02600897
|
,41:56:cancer
|
Histologically documented CD20-positive B-cell lymphoma as determined by the local laboratory
| 1
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NCT02140255
|
159:168:treatment
|
Otherwise assessed by the site investigator or designee, in consultation with the Clinical Management Committee (CMC), as having an indication to re-initiate treatment
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NCT02312518
|
81:90:treatment
|
Presence of another wound that is concurrently treated and might interfere with treatment of index wound
| 1
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NCT02514083
|
12:24:treatment
|
history of hysterectomy
| 1
|
[
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[
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0,
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NCT02719327
|
16:30:treatment
|
Current use of anticoagulants
| 1
|
[
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[
0,
0,
0,
1
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NCT01794559
|
16:34:chronic_disease
|
Diagnosis of a psychotic disorder
| 1
|
[
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[
0,
0,
0,
2,
2
] |
NCT01474889
|
25:45:chronic_disease
|
Untreated proliferative diabetic retinopathy
| 1
|
[
"Untreated",
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"diabetic",
"retinopathy"
] |
[
0,
0,
2,
2
] |
NCT02690116
|
14:22:chronic_disease
|
Uncontrolled diabetes (fatigue-related factor)
| 1
|
[
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")"
] |
[
0,
2,
0,
0,
0,
0
] |
NCT01684904
|
15:44:cancer
|
Patients with cervical esophageal carcinoma
| 1
|
[
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"carcinoma"
] |
[
0,
0,
3,
3,
3
] |
NCT01893554
|
75:84:treatment
|
Subjects with clinically insignificant cardiac abnormalities requiring no treatment may be enrolled
| 1
|
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NCT02466750
|
31:47:chronic_disease,60:106:treatment,142:157:treatment,163:173:treatment,,227:234:treatment
|
Have a personal history of an immunodeficiency or received treatment with an immunosuppressive medication, such as systemically administered glucocorticoids (eg, prednisone) within 1 month before planned administration of the vaccine
| 1
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NCT02542657
|
13:20:chronic_disease,24:43:chronic_disease,132:141:treatment
|
Any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with the completion of treatment according to this protocol
| 1
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NCT02514083
|
1:15:chronic_disease,
|
Active disease as defined by at least one of the following (IWCLL consensus criteria)
| 1
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NCT02185417
|
15:34:treatment,,
|
Are receiving hydrochlorothiazide from the VA pharmacy at a daily dose of 25 or 50 mg
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NCT02355912
|
1:20:treatment
|
Lower Limb Amputees
| 1
|
[
"Lower",
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[
1,
1,
1
] |
NCT01703117
|
18:29:treatment,89:101:treatment,184:193:treatment,195:206:treatment,208:215:treatment,217:224:treatment,226:235:treatment,237:253:treatment,262:274:treatment,279:294:treatment,296:321:treatment,323:338:treatment
|
Currently taking medications that either have evidence of glutamatergic activity or has previous MRS evidence of effects on brain glutamate levels at the discretion of the PI such as memantine, lamotrigine, lithium, opiates, bupropion, psychostimulants such as amphetamines and methylphenidate, tricyclic antidepressants, benzodiazepines and any other drug that the investigators judge might interfere with the study
| 1
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NCT00075387
|
,39:58:treatment
|
least 14 days must have elapsed since radiation treatment
| 1
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NCT02553642
|
22:40:chronic_disease
|
Subjects with active autoimmune disease, symptoms or conditions
| 1
|
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[
0,
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0,
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NCT02943915
|
1:33:chronic_disease
|
Severe muscular or skeletal pain
| 1
|
[
"Severe",
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"skeletal",
"pain"
] |
[
2,
2,
2,
2,
2
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NCT02932410
|
1:36:chronic_disease
|
pulmonary capillary hemangiomatosis
| 1
|
[
"pulmonary",
"capillary",
"hemangiomatosis"
] |
[
2,
2,
2
] |
NCT02568267
|
25:62:cancer
|
Patients diagnosed with anaplastic large cell lymphoma (ALCL) harboring a gene rearrangement of interest may be eligible
| 1
|
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NCT01670877
|
33:50:treatment,,88:109:treatment,201:210:treatment
|
The patient must have completed radiation therapy and be at least 1 week from the last systemic chemotherapy administration, with adequate recovery of bone marrow and organ functions, before starting neratinib
| 1
|
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NCT00904046
|
15:45:chronic_disease
|
Subjects with uric acid kidney stone disease
| 1
|
[
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"stone",
"disease"
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[
0,
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2,
2,
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NCT02943408
|
1:26:chronic_disease
|
major depressive disorder (296.20-296.23, 296.30-296.33)
| 1
|
[
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0,
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NCT02678910
|
29:39:cancer
|
have a medical condition or malignancy that requires removal of all or part of one or both ovaries
| 1
|
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NCT00467987
|
13:31:treatment,33:40:treatment,42:56:treatment,58:87:treatment,91:103:treatment
|
Subjects on thiazolidinediones, statins, ACE inhibitors, angiotensin receptor blockers or antioxidants will be allowed as long as they are on stable doses of these compounds and the dosage in not changed during the study
| 1
|
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NCT02929589
|
36:49:treatment,56:107:treatment,179:188:treatment,189:202:treatment,219:228:treatment,333:339:treatment,341:348:treatment,350:361:treatment,363:376:treatment,378:386:treatment,388:397:treatment,399:410:treatment,412:432:treatment
|
Elective, open unilateral inguinal herniorrhaphy using Lichtenstein (tension free with mesh) hernia repair technique Agree to take only the prescribed oral analgesic medication (oxycodone/acetaminophen), plus or minus ibuprofen, for the initial fourteen-day post-operative period, with allowed exception of any currently prescribed opioid (codeine, hydrocodone, hydromorphone, morphine, methadone, oxymorphone, transdermal fentanyl), which can be continued.Agree to honestly complete a depression screening questionnaire, illicit drug use personal history and questionnaire, and physical activity assessment questionnaire, with the knowledge that if the patient is an active duty member, this information could result in a referral to medical or command authorities for potential Uniform Code of Military Justice (UCMJ) violations or concerns for subject health and fitness for duty
| 1
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NCT02107261
|
16:24:chronic_disease
|
Patients whose dystonia is not severe enough to interfere with musical performance in the opinion of a skilled examiner
| 1
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NCT02355002
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23:33:chronic_disease,37:56:chronic_disease,64:82:chronic_disease,84:92:chronic_disease,94:106:chronic_disease,117:137:chronic_disease,186:189:treatment
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Current or history of neurologic or psychiatric disease (e.g., mental retardation, dementia, brain damage, or other cognitive impairment) that would interfere with ability to engage in TMS
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NCT01872975
|
21:34:cancer,50:63:cancer,67:80:cancer
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patients who have a primary tumor that is either HER2-positive or HER2-negative
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NCT02518594
|
18:49:chronic_disease,51:57:chronic_disease,62:68:chronic_disease
|
Active, unhealed herpetic lesion on labia minora, vagina, or cervix due to the potential for significant patient discomfort or increasing genital tract viral spread. Once lesion(s) heal and the patient is asymptomatic, she may be randomized
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NCT02921022
|
31:53:chronic_disease
|
Known, clinically significant carotid artery disease
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NCT01130077
|
19:36:cancer
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Patients with any oligodendroglioma component
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NCT02257424
|
5:32:treatment,23:32:treatment,60:68:chronic_disease
|
All prior anti-cancer treatment-related toxicities (except alopecia and laboratory values as listed in Eligibility Criteria #4) must be Grade 1 according to the Common Terminology Criteria for Adverse Events version 4 (CTCAE version 4.03, 2009) at the time of starting treatment
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NCT02074631
|
233:238:treatment,
|
Clinically significant fractures as defined by ISCD (a long bone fracture of the lower extremities, vertebral compression fracture, or two or more long bone fractures of the upper extremities) (88,89) indicated by a cast or a spine x-ray within the last 2 weeks
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NCT02208362
|
,123:140:treatment
|
Radiographic evidence of progression/recurrence of the measurable disease more than 12 weeks after the end of the initial radiation therapy
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NCT02543944
|
1:23:chronic_disease
|
3rd degree heart block
| 1
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[
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[
2,
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2,
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NCT02564198
|
43:53:cancer
|
participants with recurrent or refractory CNS tumors
| 1
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NCT01869114
|
15:47:chronic_disease,49:64:chronic_disease,78:102:chronic_disease,104:125:chronic_disease,,175:193:chronic_disease
|
Patients with uncontrolled high blood pressure, unstable angina, symptomatic congestive heart failure, myocardial infarction within the past 6 months or serious uncontrolled cardiac arrhythmia
| 1
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NCT01616108
|
1:21:chronic_disease
|
Paralytic strabismus
| 1
|
[
"Paralytic",
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[
2,
2
] |
NCT02309580
|
56:75:cancer
|
Patients who have a standard curative option for their lymphoid malignancy at current state of disease
| 1
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NCT02207465
|
26:56:cancer
|
Pathologically confirmed adenocarcinoma of the pancreas
| 1
|
[
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NCT01174108
|
18:36:treatment,48:57:treatment,70:76:chronic_disease,78:80:chronic_disease,82:97:chronic_disease,99:124:chronic_disease,133:146:chronic_disease,150:165:chronic_disease
|
Unfit to receive filgrastim (G-CSF) or undergo apheresis (history of stroke, MI, unstable angina, uncontrolled hypertension, severe heart disease or palpable spleen)
| 1
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NCT02124772
|
33:67:treatment,75:89:treatment,91:101:treatment,113:126:treatment,135:182:treatment
|
Part B, Part C and Part D only: Previous treatment with dabrafenib or any BRAF inhibitor, trametinib or another MEK inhibitor, or and Extracellular signal-regulated kinase inhibitor
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NCT02451436
|
1:16:chronic_disease
|
Sleep disorders
| 1
|
[
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[
2,
2
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NCT01804465
|
27:61:cancer,63:81:treatment,111:118:treatment,126:155:treatment
|
Histologically confirmed, metastatic prostate adenocarcinoma (positive bone scan and/or measurable disease on CT scan and/or MRI of the abdomen and pelvis)
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NCT01522768
|
59:79:treatment,,
|
HER2 overexpression and/or amplification as determined by immunohistochemistry (3+) or FISH (≥2.0)
| 1
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NCT02484248
|
1:19:treatment,25:47:treatment,52:63:treatment
|
previous treatment with acid-reduction therapy and montelukast with a level 3 (as defined below)or lesser response
| 1
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NCT02091141
|
33:46:chronic_disease,75:102:treatment,137:148:treatment
|
Refractory nausea and vomiting, malabsorption, external biliary shunt, or significant bowel resection that would preclude absorption of vemurafenib
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NCT02826577
|
30:33:treatment
|
Have a counter indication to EEG
| 1
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0,
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NCT01698658
|
11:25:chronic_disease
|
No active skin infection
| 1
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[
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[
0,
0,
2,
2
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NCT02421380
|
48:60:chronic_disease,85:93:cancer,100:103:treatment
|
Patients identified by a radiologist to have a brain lesion with high suspicion for neoplasm given MRI features
| 1
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NCT01773707
|
9:25:chronic_disease
|
Have an active infection at time of randomization
| 1
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NCT02354547
|
15:50:cancer
|
Patients with relapsed or refractory solid tumors
| 1
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0,
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NCT02056873
|
24:46:treatment,47:88:treatment,90:93:treatment
|
Must have been offered habit reversal therapy/cognitive behavioral intervention therapy (HRT) if subject did not have it prior to enrollment
| 1
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NCT02415387
|
1:11:treatment,36:44:treatment,56:63:treatment,74:85:treatment,91:108:treatment
|
Medication exclusions will include steroids as well as statins and other medications with anti-inflammatory actions
| 1
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NCT02912572
|
33:45:treatment
|
patients who have only received chemotherapy in the adjuvant setting
| 1
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NCT02481765
|
66:78:treatment
|
Intensive medical treatment means that the subject is undergoing chemotherapy for a hematologic/oncologic condition, is carrying a pacemaker or has been diagnosed with a cardiac anomaly which causes cardiac insufficiency not compensated with medications
| 1
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NCT03101566
|
19:43:chronic_disease,45:59:chronic_disease,75:94:treatment,96:110:chronic_disease,120:128:chronic_disease,130:139:chronic_disease,144:152:chronic_disease,168:186:treatment
|
Participants with type I diabetes mellitus, hypothyroidism only requiring hormone replacement, skin disorders (such as vitiligo, psoriasis, or alopecia) not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger are permitted to enroll
| 1
|
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NCT01851369
|
61:72:treatment
|
Patients must be able to swallow whole tablets or capsules; nasogastric or G-tube administration is not allowed
| 1
|
[
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NCT02496208
|
,91:106:treatment,118:128:cancer,144:162:treatment
|
For disease specific studies: the subject has had evidence within 2 years of the start of study treatment of another malignancy which required systemic treatment
| 1
|
[
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NCT02346201
|
22:41:treatment,46:59:treatment,61:70:treatment,79:89:treatment,137:152:treatment,183:211:treatment,216:241:treatment,,
|
Currently taking any amphetamine product, an antipsychotic, bupropion, or any medication that would prohibit the safe concurrent use of methylphenidate, including but not limited to monoamine oxidase inhibitors and tricyclic antidepressants within the 30 days preceding randomization or a period of time equal to 5 half-lives of drug, whichever period of time is longer
| 1
|
[
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NCT00887146
|
38:47:treatment,71:87:treatment,91:107:treatment,119:125:cancer,151:179:treatment
|
if they are receiving other specific treatment (with the exclusion of hormonal therapy or Her-2 inhibitors) for their cancer or if they have received prior total body irradiation which included the brain
| 1
|
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NCT01526603
|
40:52:treatment
|
Recovery from last induction course of chemotherapy
| 1
|
[
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[
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