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NCT01351103 | 15:21:cancer | patients with tumors of any histological origin with documented genetic alterations upstream in the Wnt signaling pathway (e.g. RNF43 or RSPO fusion) are eligible with prior agreement with Novartis | 2 | [
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NCT01525901 | 1:13:chronic_disease | valvulopathy | 2 | [
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NCT02477839 | 13:21:chronic_disease,49:65:chronic_disease,93:118:chronic_disease,120:141:cancer,145:163:chronic_disease | Subject has epilepsy secondary to a progressing cerebral disease or any other progressively neurodegenerative disease (malignant brain tumor or Rasmussen Syndrome) | 2 | [
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NCT02473354 | 18:37:chronic_disease | has a history of sickle cell disease [self-reported] | 2 | [
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NCT02243813 | 7:28:chronic_disease | Has a psychiatric condition judged to be incompatible with establishment of rapport or safe exposure to psilocybin | 2 | [
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NCT03018704 | 1:34:chronic_disease | imminent suicide or violence risk | 2 | [
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NCT02509546 | 14:42:cancer | Diagnosis of acute promyelocytic leukemia | 2 | [
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NCT02546583 | ,37:45:treatment | At least 6 hours since last dose of diuretic | 2 | [
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NCT02043548 | ,21:32:treatment,34:38:treatment,42:58:treatment | 3 month washout for leflunomide, IVIg or cyclophosphamide | 2 | [
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NCT02541903 | 1:25:cancer | ductal carcinoma in situ | 2 | [
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NCT02068092 | 14:46:cancer,48:63:treatment,68:87:cancer | Diagnosis of lobular carcinoma in situ (LCIS), atypical ductal, or lobular hyperplasia | 2 | [
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NCT02458482 | 98:128:treatment, | Patients who present from a referring facility or Primary Care Physician (PCP) and have received systemic corticosteroids (SCS) within one hour of initial AAIRS scoring will also be included | 2 | [
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NCT01430390 | 15:19:treatment,100:113:treatment,165:177:treatment, | The patient's HSCT donor, or if HSCT donor is not available a third party donor, must consent to a leukapheresis or whole blood donation(s) obtained at one or more phlebotomies which, in aggregate, will total approximately 250 ml for adults and no more than 5ml/kg per draw from pediatric donors | 2 | [
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NCT02455193 | 13:40:chronic_disease,48:73:chronic_disease,82:102:chronic_disease | Significant endocrine/metabolic disease (e.g., uncontrolled hypertension, severe hypertriglyceridemia) | 2 | [
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NCT02145351 | 9:33:chronic_disease | Chronic stable exertional angina | 2 | [
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NCT02507011 | 1:20:treatment, | RVEF by cardiac MRI < 45% | 2 | [
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NCT02479698 | 1:50:cancer | Merkel polyoma-virus related Merkel cell tumor(s) with measurable disease on imaging per RECIST criteria | 2 | [
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NCT02202369 | 36:56:treatment | Subjects undergoing a single level lumbar decompression and fusion | 2 | [
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NCT02845596 | 1:48:chronic_disease | Inherited bone marrow failure syndromes (IBMFS) | 2 | [
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NCT02700451 | ,,22:42:treatment | Require 1 or 2 level lumbar spinal fusion through posterior or lateral approach | 2 | [
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NCT02504866 | 3:30:treatment | A ventriculo-peritoneal shunt | 2 | [
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NCT02351544 | 67:89:treatment,107:124:chronic_disease,115:124:chronic_disease | Those patients are included because there is no consensus whether surgical decompression is effective for chronic migraines only, or for chronic and episodic migraines. One of the goals of this trial is to determine this | 2 | [
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NCT01734512 | 1:22:cancer | Pilocytic Astrocytoma - 90600112 | 2 | [
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NCT00338377 | 18:33:treatment,61:73:treatment,74:87:treatment | Is not receiving B-RAF treatment (Cohort C) (Turnstile II - Chemotherapy/Cell Infusion Exclusion Criteria) | 2 | [
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NCT01420887 | 36:52:treatment | Not possible to have postoperative physical therapy appointment | 2 | [
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NCT02262832 | 17:28:treatment | Availability of metreleptin to the patient either as an approved drug, or through local compassionate use or expanded access programs | 2 | [
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NCT02522715 | 1:16:treatment | Metastatic CRPC | 2 | [
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NCT02538198 | 71:83:treatment | no dosing or adverse event data are currently available on the use of lenalidomide in patients | 2 | [
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NCT02122081 | 29:103:treatment, | Interval between completing treatment with a hypomethylating agent or other non-cytotoxic chemotherapy and the start of conditioning regimen must be at least 10 days | 2 | [
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NCT01787682 | 26:46:treatment | Current use of long-term oral corticosteroids (CHF only) | 2 | [
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NCT02490631 | 9:18:chronic_disease | Current infection | 2 | [
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NCT01990209 | ,,,51:64:chronic_disease | New York Heart Association (NYHA) Class III or IV heart failure | 2 | [
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NCT02167009 | 12:33:treatment,35:49:treatment,54:71:treatment | History of open prostate surgery, radiofrequency, or microwave therapy | 2 | [
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NCT01619761 | ,,,,283:295:treatment | Woman with child bearing potential must either commit to continued abstinence from heterosexual intercourse or begin TWO acceptable methods of birth control, one highly effective method and one additional effective method AT THE SAME TIME, at least 4 weeks before she starts taking lenalidomide | 2 | [
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NCT01794559 | 17:28:treatment,,63:76:treatment,94:97:treatment, | ble to stop all medications (wash out) for 5 half-lves of all medication(s) which affect the EEG. Outpatient subjects are eligible if they can be washed out of their medications in 14 days or less | 2 | [
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NCT03143153 | 11:28:cancer | Must have esophageal cancer that cannot be operated on, or treated with definitive chemoradiation with curative intent, that is advanced, reoccurring or has spread out | 2 | [
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NCT01444209 | 28:33:cancer,54:57:treatment,61:63:treatment | Patients must have visible tumor on imaging studies (MRI or CT) | 2 | [
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NCT03086369 | 9:33:cancer | Current hematologic malignancies | 2 | [
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NCT02429934 | 15:31:chronic_disease,42:46:treatment,50:64:treatment,,99:115:treatment | Subjects with active infection requiring oral or IV antibiotics within one month of first dose of study medication | 2 | [
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NCT01420887 | 18:34:chronic_disease | Current or prior septic arthritis | 2 | [
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NCT02033941 | 35:41:chronic_disease | History of clinically significant stroke | 2 | [
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NCT01591356 | 38:60:chronic_disease,90:102:chronic_disease,126:147:chronic_disease,151:166:chronic_disease,,,252:284:chronic_disease,294:312:chronic_disease,347:382:chronic_disease,409:446:chronic_disease,465:477:chronic_disease | Patients with clinically significant cardiovascular disease; this includes: uncontrolled hypertension (greater than 140/90); myocardial infarction or unstable angina within 6 months prior to registration; New York Heart Association (NYHA) grade II or greater congestive heart failure; serious cardiac arrhythmia requirin... | 2 | [
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NCT02862938 | 17:45:chronic_disease,,71:91:chronic_disease,113:133:chronic_disease | Participant has choroidal neovascularization secondary to age related macular degeneration or any other type of retinal degeneration that may interfere with the study procedures, evaluations and outcome assessments | 2 | [
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NCT03123783 | 29:40:chronic_disease,55:70:treatment | History of (non-infectious) pneumonitis that required corticosteroids or current pneumonitis | 2 | [
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NCT02570854 | 14:34:chronic_disease,,,,, | Uncontrolled renal osteodystrophy defined asthe coexistence of all of the following at screening (1) intact PTH ≥ 750 pg/mL, (2) serum phosphate above the upper limit of the lab normal range, and (3) calcium x phosphate product > 75 mg2/dL2 (6.05 mmol2/L2) | 2 | [
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NCT02273362 | 21:43:treatment, | Receiving any other investigational agents =< 6 months prior to registration | 2 | [
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NCT02159495 | 104:113:allergy_name | History of allergic reactions attributed to compounds of similar chemical or biological composition to cetuximab | 2 | [
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NCT02468453 | 31:40:treatment,42:54:treatment,58:102:treatment,,122:131:treatment | Subject has systemically used retinoids, antioxidants or medical grade of skin nourishing supplements within 2 months of treatment or during the study | 2 | [
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NCT02389465 | 76:86:allergy_name,90:102:allergy_name,114:123:allergy_name,125:132:allergy_name,143:149:allergy_name,218:230:allergy_name | Known history of relevant severe drug allergy or hypersensitivity (e.g. to Citalopram or Escitalopram, and/or to celecoxib, aspirin, or other NSAIDs only for Phase 2; known demonstration of allergic-type reactions to sulfonamides) | 2 | [
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NCT02740595 | 1:18:chronic_disease | Diabetes mellitus | 2 | [
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NCT02725177 | 21:31:cancer,55:85:cancer,89:116:cancer,121:147:cancer, | Have any history of malignancy, except fully resected cutaneous squamous cell cancer or cutaneous basal cell cancer, or cervical carcinoma in-situ with a minimum of 5 years period without recurrence | 2 | [
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NCT02563678 | 16:33:treatment, | presenting for hyperbaric oxygen for acute carbon monoxide poisoning (up to 3 sessions) | 2 | [
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NCT02473250 | 10:23:chronic_disease | lifetime schizophrenia | 2 | [
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NCT02502006 | 1:12:chronic_disease,14:22:chronic_disease,26:41:chronic_disease | coagulation, bleeding or blood disorders | 2 | [
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NCT03130218 | 8:31:chronic_disease,40:46:chronic_disease,50:94:chronic_disease | Severe reactive airway disease such as asthma or chronic obstructive pulmonary disease (COPD) | 2 | [
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NCT02634957 | 1:28:chronic_disease | Sub-epithelial fibrous mass | 2 | [
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NCT02522715 | 1:18:treatment,,,, | Aminoglutethimide; approximate half-life: 15 hours; washout period required: 4 days | 2 | [
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NCT01835626 | 1:24:treatment,7:16:treatment,123:142:treatment | Prior radiation therapy is acceptable but there cannot be major overlap of the previously irradiated tissues with the new radiation treatment volumes anticipated to be delivered for the purposes of this protocol, in such a way that curative intent with radiation cannot be met | 2 | [
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NCT02076906 | 10:29:treatment,31:43:treatment,45:63:treatment,65:82:treatment,104:118:treatment,109:118:treatment | No other anti-cancer therapy (chemotherapy, biological therapy, radiation therapy) is permitted during HIFU treatment and post treatment follow up for tolerability | 2 | [
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NCT02901067 | 1:17:chronic_disease,, | Thrombocytopenia (platelet count < 50,000) | 2 | [
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NCT03182907 | 41:44:chronic_disease | At screening has suspected or confirmed CDI | 2 | [
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NCT02101853 | 28:44:chronic_disease | Patients with uncontrolled seizure disorder | 2 | [
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NCT02772302 | 1:26:chronic_disease | Minimally conscious state | 2 | [
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NCT02176902 | 24:28:allergy_name | Patient has allergy to fish | 2 | [
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NCT01880567 | 17:20:chronic_disease,28:37:treatment,43:52:treatment | Newly diagnosed MCL: Prior treatment with ibrutinib | 2 | [
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NCT01624090 | ,47:76:treatment | At least 3 half-lives must have elapsed since monoclonal antibody treatment | 2 | [
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NCT00391170 | 24:41:chronic_disease | Clinically significant oral chronic GVHD at the time of the screening | 2 | [
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NCT02431806 | 24:48:chronic_disease | Clinically significant cardiovascular disorders | 2 | [
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NCT02061553 | 8:25:chronic_disease | active suicidal ideation | 2 | [
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NCT02312518 | 18:38:chronic_disease | Subjects who are cognitively impaired and do not have a healthcare proxy | 2 | [
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NCT02316886 | 51:76:treatment, | Contraindication to or planned discontinuation of dual antiplatelet therapy within 1 year | 2 | [
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NCT02512926 | ,103:125:chronic_disease,132:141:cancer,143:155:chronic_disease | Patients must meet the WHO classification with ≥ 5% blasts in the bone marrow or must have definitive extramedullary disease (e.g. chloromas, skin lesions) | 2 | [
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NCT02995733 | 22:33:allergy_name | Known allergy to the ICS inhaler used in the study | 2 | [
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NCT02159027 | 78:98:chronic_disease | Ability and willingness to provide written informed consent Mild to moderate cognitive impairment with global neuropsychological (NP) test (NPZglobal) | 2 | [
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NCT02132598 | 26:48:treatment,60:98:treatment,103:118:treatment,126:135:treatment,139:149:treatment,161:192:treatment,,213:225:treatment,227:238:treatment,,285:294:treatment | The subject has received cytotoxic chemotherapy (including investigational cytotoxic chemotherapy) or biologic agents (e.g., cytokines or antibodies; including investigational biologic agents) within 3 weeks, or nitrosoureas/ mitomycin C within 6 weeks before the first dose of study treatment | 2 | [
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NCT02471430 | 1:6:chronic_disease | HIV-1 infection prior to entry | 2 | [
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NCT02979366 | ,61:76:treatment | already enrolled in the study who has received at least one S64315 infusion | 2 | [
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NCT02953509 | 1:18:cancer, | Second malignancy within the last 3 years | 2 | [
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NCT02523443 | 21:35:treatment,36:57:treatment,64:77:treatment | Patients taking any opioid agonist/antagonist medication (i.e. Buprenorphine) | 2 | [
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NCT02494141 | 12:27:treatment, | History of hospitalization within the last 3 months | 2 | [
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NCT02053909 | 12:39:chronic_disease | History of gastrointestinal hemorrhage | 2 | [
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