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NCT01903330
26:40:treatment
Anticipation of need for major surgical procedure during the course of the study
2
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NCT00909909
4:31:cancer
No Paget disease of the nipple
2
[ "No", "Paget", "disease", "of", "the", "nipple" ]
[ 0, 3, 3, 3, 3, 3 ]
NCT02624765
1:20:chronic_disease
sick sinus syndrome
2
[ "sick", "sinus", "syndrome" ]
[ 2, 2, 2 ]
NCT02374333
1:13:chronic_disease,37:44:treatment,110:122:chronic_disease
CNS3 disease that is progressive on therapy, or with CNS parenchymal lesions that might increase the risk of CNS toxicity
2
[ "CNS3", "disease", "that", "is", "progressive", "on", "therapy", ",", "or", "with", "CNS", "parenchymal", "lesions", "that", "might", "increase", "the", "risk", "of", "CNS", "toxicity" ]
[ 2, 2, 0, 0, 0, 0, 1, 0, 0, 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02832115
41:50:allergy_name
Hypersensitivity or contraindication to lidocaine
2
[ "Hypersensitivity", "or", "contraindication", "to", "lidocaine" ]
[ 0, 0, 0, 0, 4 ]
NCT02516332
28:35:chronic_disease,,,,188:203:chronic_disease,205:219:chronic_disease,224:238:chronic_disease
Patients also will have an anxiety symptom severity score of at least 8 on the Hospital Anxiety and Depression-Anxiety scale (HADS-A) or a DSM-5 diagnosis of an Anxiety Disorder, such as General Anxiety, Social Anxiety, or Panic Disorder
2
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NCT02434809
32:38:allergy_name
History of hypersensitivity to nickel
2
[ "History", "of", "hypersensitivity", "to", "nickel" ]
[ 0, 0, 0, 0, 4 ]
NCT02451982
54:74:chronic_disease
Conditions, including alcohol or drug dependence, or intercurrent illness that would affect the patient's ability to comply with study visits and procedures
2
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NCT01465100
7:34:chronic_disease
Known biopterin synthesis defects
2
[ "Known", "biopterin", "synthesis", "defects" ]
[ 0, 2, 2, 2 ]
NCT02081404
18:36:treatment
Prior history of esophageal surgery
2
[ "Prior", "history", "of", "esophageal", "surgery" ]
[ 0, 0, 0, 1, 1 ]
NCT03125902
7:43:chronic_disease
Known central nervous system (CNS) disease
2
[ "Known", "central", "nervous", "system", "(", "CNS", ")", "disease" ]
[ 0, 2, 2, 2, 2, 2, 0, 0 ]
NCT02347995
11:27:chronic_disease
untreated major depression by clinical interview
2
[ "untreated", "major", "depression", "by", "clinical", "interview" ]
[ 0, 2, 2, 0, 0, 0 ]
NCT02533674
43:54:treatment
Patients who have previously discontinued gemcitabine-containing regimens due to gemcitabine-related toxicity
2
[ "Patients", "who", "have", "previously", "discontinued", "gemcitabine-containing", "regimens", "due", "to", "gemcitabine-related", "toxicity" ]
[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]
NCT02378428
106:123:treatment
The presence of mixed response (MR), or no response (NR) following the completion of A3973 or equivalent induction therapy
2
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NCT02204956
1:43:treatment
Mini-Mental State Examination (MMSE: [45])
2
[ "Mini-Mental", "State", "Examination", "(", "MMSE", ":", "[", "45", "]", ")" ]
[ 1, 1, 1, 1, 1, 0, 0, 0, 0, 0 ]
NCT00719888
1:29:cancer,31:57:cancer,59:62:cancer,63:66:cancer,69:98:cancer,100:126:cancer,130:149:cancer,,200:215:treatment
Chronic lymphocytic leukemia /small lymphocytic lymphoma (CLL/SLL), marginal zone B-cell lymphoma, lymphoplasmacytic lymphoma or follicular lymphoma that have progressed after at least two different prior therapies
2
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NCT02075671
13:22:chronic_disease
Scarring or infection in the area being treated
2
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[ 0, 0, 2, 0, 0, 0, 0, 0 ]
NCT02075671
8:31:treatment,
Use of topical corticosteroids (on the face) 1 month prior to Visit 1
2
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NCT02319369
23:92:treatment
receiving concomitant treatment with a strong inhibitor or inducer of cytochrome P450 3A4/5
2
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[ 0, 0, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1 ]
NCT02549937
15:26:treatment
Currently use medications known to cause QT prolongation or Torsades de Pointes
2
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[ 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02167009
12:30:treatment
History of pelvic irradiation
2
[ "History", "of", "pelvic", "irradiation" ]
[ 0, 0, 1, 1 ]
NCT02397083
64:115:treatment,
Patients who are currently part of or have participated in any clinical investigation with an investigational drug within 1 month prior to dosing
2
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NCT02881320
11:16:chronic_disease,,,,,,
Cohort 1: HIV-1 infected adolescents (12 to < 18 years of age and screening weight ≥ 35 kg) who are virologically suppressed for ≥ 6 months prior to screening
2
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NCT02145351
9:33:chronic_disease
Complex congenital heart disease
2
[ "Complex", "congenital", "heart", "disease" ]
[ 0, 2, 2, 2 ]
NCT02637947
13:28:chronic_disease
subject has unstable angina
2
[ "subject", "has", "unstable", "angina" ]
[ 0, 0, 2, 2 ]
NCT02496208
23:34:chronic_disease
appearance of one new bone lesion
2
[ "appearance", "of", "one", "new", "bone", "lesion" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT02607514
8:23:chronic_disease
Active suicidal intent within the past year (yes on item 4 or 5 on the Columbia-Suicide Severity Rating Scale)
2
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[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT00924027
1:19:cancer
distant metastases
2
[ "distant", "metastases" ]
[ 3, 3 ]
NCT02252081
12:21:treatment,33:51:treatment,72:81:treatment,85:103:chronic_disease,
History of metformin use or any insulin sensitizer or any drug for the treatment of metabolic syndrome over the last one year
2
[ "History", "of", "metformin", "use", "or", "any", "insulin", "sensitizer", "or", "any", "drug", "for", "the", "treatment", "of", "metabolic", "syndrome", "over", "the", "last", "one", "year" ]
[ 0, 0, 1, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 1, 0, 2, 2, 0, 0, 0, 0, 0 ]
NCT02952365
40:53:treatment
Subjects who have previously undergone LASIK surgery
2
[ "Subjects", "who", "have", "previously", "undergone", "LASIK", "surgery" ]
[ 0, 0, 0, 0, 0, 1, 1 ]
NCT02507232
31:46:treatment,48:60:treatment,62:74:treatment,85:110:treatment,127:138:cancer
Disease that has not received prior radiation, radiosurgery, chemotherapy, or other investigational treatment directed at the brain tumor at any time. Previous surgical procedures
2
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NCT01883258
,29:56:treatment
postmenopausal women taking hormone replacement therapy
2
[ "postmenopausal", "women", "taking", "hormone", "replacement", "therapy" ]
[ 0, 0, 0, 1, 1, 1 ]
NCT02342782
1:22:treatment,10:22:treatment,26:35:treatment,,87:91:treatment,100:124:treatment,148:177:treatment
Systemic chemotherapy or radiation cannot have been given within 4 weeks prior to the Y-90 dose of radioimmunotherapy (RIT), with the exception of single agent cyclophosphamide priming chemotherapy administered for mobilization
2
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NCT03051282
27:37:chronic_disease
Subject with a history of angioedema
2
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[ 0, 0, 0, 0, 0, 2 ]
NCT02525861
48:55:chronic_disease,57:68:chronic_disease,73:90:chronic_disease,141:156:chronic_disease,158:183:chronic_disease
The participant has any clinically significant medical, psychiatric, or cognitive illness, or any other uncontrolled medical condition (eg, unstable angina, transient ischemic attack) that, in the opinion of the investigator, would impede the participant's ability to comply with the study procedures, pose increased ris...
2
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NCT03037385
11:17:cancer
Patient's cancer has a known primary driver alteration other than RET
2
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NCT02965638
1:13:chronic_disease,17:31:chronic_disease
Fetal mitral or aortic atresia
2
[ "Fetal", "mitral", "or", "aortic", "atresia" ]
[ 2, 2, 0, 2, 2 ]
NCT02273375
47:71:cancer
Histologically confirmed diagnosis of primary non-small cell carcinoma of the lung
2
[ "Histologically", "confirmed", "diagnosis", "of", "primary", "non-small", "cell", "carcinoma", "of", "the", "lung" ]
[ 0, 0, 0, 0, 0, 3, 3, 3, 0, 0, 0 ]
NCT03182907
17:44:treatment,
Has received an investigational study agent within the previous 30 days
2
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[ 0, 0, 0, 1, 1, 1, 0, 0, 0, 0, 0 ]
NCT02215096
24:38:chronic_disease
History or evidence of cardiovascular risk
2
[ "History", "or", "evidence", "of", "cardiovascular", "risk" ]
[ 0, 0, 0, 0, 2, 0 ]
NCT02579265
1:33:chronic_disease
Cyanotic congenital heart defect
2
[ "Cyanotic", "congenital", "heart", "defect" ]
[ 2, 2, 2, 2 ]
NCT01835626
108:118:treatment
Agreement not to donate blood or blood products during the study and for 7 months after discontinuation of vismodegib
2
[ "Agreement", "not", "to", "donate", "blood", "or", "blood", "products", "during", "the", "study", "and", "for", "7", "months", "after", "discontinuation", "of", "vismodegib" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
NCT02480114
24:34:treatment
Prior non-tolerance of gabapentin
2
[ "Prior", "non-tolerance", "of", "gabapentin" ]
[ 0, 0, 0, 1 ]
NCT02076906
15:22:chronic_disease
Defined as no dyspnea at rest
2
[ "Defined", "as", "no", "dyspnea", "at", "rest" ]
[ 0, 0, 0, 2, 0, 0 ]
NCT02429349
34:41:cancer,60:78:cancer,87:95:cancer,100:120:cancer
include, but are not limited to, cancers with high risk of ovarian metastasis such as leukemia and non-Hodgkin lymphoma
2
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NCT01703117
1:20:chronic_disease
Lactose intolerance
2
[ "Lactose", "intolerance" ]
[ 2, 2 ]
NCT02217709
24:29:chronic_disease,33:58:chronic_disease,60:73:chronic_disease,75:91:chronic_disease,100:116:chronic_disease,127:142:treatment
Known prior history of mania or major psychiatric illness (schizophrenia, bipolar disorder, severe major depression requiring hospitalization, etc.)
2
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NCT02311361
22:48:chronic_disease,50:57:chronic_disease,59:66:chronic_disease,69:92:chronic_disease,94:108:chronic_disease,137:153:chronic_disease
Active or history of inflammatory bowel disease (colitis, Crohn s), irritable bowel disease, celiac disease, or other serious, chronic, gastrointestinal conditions associated with diarrhea
2
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NCT02058095
1:40:chronic_disease
Obstructive Hypertrophic cardiomyopathy
2
[ "Obstructive", "Hypertrophic", "cardiomyopathy" ]
[ 2, 2, 2 ]
NCT01245712
34:39:cancer,48:79:cancer,92:120:cancer
On histological examination, the tumor must be ductal carcinoma in situ (DCIS) or invasive adenocarcinoma of the breast
2
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NCT02656706
7:17:cancer,,80:87:cancer,129:163:cancer,165:191:cancer,196:229:cancer
Prior malignancy active within the previous 2 years except for locally curable cancers that have been apparently cured, such as basal or squamous cell skin cancer, superficial bladder cancer, or carcinoma in situ of the prostate, cervix, or breast
2
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NCT02856412
19:23:chronic_disease,
Meet criteria for PTSD of at least 3 months duration
2
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[ 0, 0, 0, 2, 0, 0, 0, 0, 0, 0 ]
NCT03013543
1:17:chronic_disease
Alström Syndrome
2
[ "Alström", "Syndrome" ]
[ 2, 2 ]
NCT02978885
,,,,,,132:147:treatment
forced expiratory volume 1 (FEV1)/forced vital capacity (FVC) <0.70 and FEV1 50-79% normal) undergoing Whipple procedures or other major surgeries
2
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NCT02911792
1:124:treatment
Ingestion of medications known to interfere with the renin-angiotensin system or renal function, including diuretic therapy
2
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NCT02466685
25:47:treatment,55:62:treatment,64:73:treatment,78:86:treatment,
Individuals receiving a single mood stabilizer (e.g., lithium. valproate, or lamictal) are allowed if a stable dose has been maintained for at least 2 months prior to screening
2
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NCT02880215
17:35:chronic_disease,37:53:chronic_disease,58:71:chronic_disease
current or past psychotic disorder, bipolar disorder, or schizophrenia
2
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[ 0, 0, 0, 2, 2, 0, 2, 2, 0, 0, 2 ]
NCT02329652
1:19:chronic_disease
multiple sclerosis
2
[ "multiple", "sclerosis" ]
[ 2, 2 ]
NCT02469857
7:20:chronic_disease,,,
Known HIV infection with CD4 count < 200 cells/mm3 or < 14% of all lymphocytes
2
[ "Known", "HIV", "infection", "with", "CD4", "count", "<", "200", "cells/mm3", "or", "<", "14", "%", "of", "all", "lymphocytes" ]
[ 0, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01614197
108:119:treatment
Patients with known optic nerve and/or retinal involvement (because it may not be possible to safely delay irradiation) are not eligible
2
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NCT02898597
18:30:chronic_disease
Having an active skin disease
2
[ "Having", "an", "active", "skin", "disease" ]
[ 0, 0, 0, 2, 2 ]
NCT02582957
44:62:treatment,77:81:chronic_disease
Treating physicians being unwilling to use low VT ventilation strategy when ARDS is diagnosed as low VT ventilation is now considered standard of care for patients with ARDS
2
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NCT02320292
14:24:cancer,35:44:treatment,106:114:cancer
Active other malignancy requiring treatment that would interfere with the assessments of response of the lymphoma to protocol treatment and would interfere with follow-up assessments through year 5
2
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NCT01625234
65:87:cancer
Histologically or cytologically confirmed diagnosis of advanced solid tumor malignancy
2
[ "Histologically", "or", "cytologically", "confirmed", "diagnosis", "of", "advanced", "solid", "tumor", "malignancy" ]
[ 0, 0, 0, 0, 0, 0, 0, 3, 3, 3 ]
NCT02159495
99:123:treatment,131:154:treatment,,,306:321:treatment
Research participant with central nervous system (CNS) leukemic involvement that is refractory to intrathecal chemotherapy and/or cranio-spinal radiation but effectively treated to completion remission (< 5 white blood cell[WBC]/mm^3 and no blast in cerebrospinal fluid [CSF]) is eligible to proceed with lymphodepletion
2
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NCT03119363
,,,71:75:treatment
Who are currently over age 18 and were at least age 16 at the time of ASCT
2
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NCT01878617
12:36:chronic_disease
except for posterior fossa syndrome
2
[ "except", "for", "posterior", "fossa", "syndrome" ]
[ 0, 0, 2, 2, 2 ]
NCT01703117
6:30:chronic_disease
with mild Alzheimer's disease determined after neurological and neuropsychological evaluation following the National Institute on Aging - Alzheimer's disease Association criteria that recently revisited the NINCDS-ADRDA criteria
2
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NCT01701986
1:30:treatment
Prior whole brain irradiation
2
[ "Prior", "whole", "brain", "irradiation" ]
[ 1, 1, 1, 1 ]
NCT02639065
1:24:chronic_disease
Ventricular arrhythmias requiring medication(s)
2
[ "Ventricular", "arrhythmias", "requiring", "medication", "(", "s", ")" ]
[ 2, 2, 0, 0, 0, 0, 0 ]
NCT03023059
7:25:chronic_disease
Known retinal hemorrhage
2
[ "Known", "retinal", "hemorrhage" ]
[ 0, 2, 2 ]
NCT02574910
16:38:chronic_disease
A history of a malabsorption syndrome
2
[ "A", "history", "of", "a", "malabsorption", "syndrome" ]
[ 0, 0, 0, 0, 2, 2 ]
NCT02335242
47:69:chronic_disease,
Be required to have the clinical diagnosis of lymphatic malformation that appears to be over 3 cm in greatest diameter in order to be evaluated for entry
2
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NCT02004275
1:13:treatment,14:32:cancer,,122:150:treatment
Lenalidomide-refractory disease is defined as disease progression on or progression within 60 days of the last dose of a lenalidomide-based treatment
2
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NCT02703220
27:45:chronic_disease,117:145:chronic_disease,146:166:chronic_disease,,
Patients with significant pulmonary diseases by history and abnormal pulmonary function testing, including moderate obstructive/restrictive lung/chest wall disorders with resting oxygen saturation of <96% or on supplemental oxygen
2
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NCT02203695
1:20:chronic_disease,
Uncontrolled angina within 3 months of Screening visit
2
[ "Uncontrolled", "angina", "within", "3", "months", "of", "Screening", "visit" ]
[ 2, 2, 0, 0, 0, 0, 0, 0 ]
NCT01896999
30:45:treatment
no upper limit for number of prior therapies
2
[ "no", "upper", "limit", "for", "number", "of", "prior", "therapies" ]
[ 0, 0, 0, 0, 0, 0, 1, 1 ]
NCT02169089
1:24:chronic_disease,26:51:chronic_disease,53:56:chronic_disease,60:82:chronic_disease,,111:148:treatment,
Acute coronary syndrome, Transient ischemic attack, CVA or critical limb ischemia during the last 6 months or coronary/peripheral revascularization within the last 3 months
2
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NCT02059239
106:117:treatment
History of allergic reactions attributed to compounds of similar chemical or biologic composition to any medications listed in the protocol
2
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NCT02421315
77:80:chronic_disease
Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) Diagnosis of OCD as the principal problem
2
[ "Diagnostic", "and", "Statistical", "Manual", "of", "Mental", "Disorders", "(", "DSM-IV", ")", "Diagnosis", "of", "OCD", "as", "the", "principal", "problem" ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0 ]
NCT01061515
,72:90:treatment
Provided the patient has been allowed at least 4 weeks to recover from surgical debulking, no additional recovery time is required for port placement
2
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NCT02703090
1:19:chronic_disease
Neurologic disease
2
[ "Neurologic", "disease" ]
[ 2, 2 ]
NCT02678351
9:49:treatment
Planned prostatectomy with lymph node dissection
2
[ "Planned", "prostatectomy", "with", "lymph", "node", "dissection" ]
[ 0, 1, 1, 1, 1, 1 ]
NCT02314221
8:34:chronic_disease
Severe concurrent medical disease, illness or condition
2
[ "Severe", "concurrent", "medical", "disease", ",", "illness", "or", "condition" ]
[ 0, 2, 2, 2, 0, 0, 0, 0 ]
NCT02570984
1:11:treatment,15:41:treatment,53:68:treatment
Prior IVIG or systemic immunosuppressant other than corticosteroids
2
[ "Prior", "IVIG", "or", "systemic", "immunosuppressant", "other", "than", "corticosteroids" ]
[ 1, 1, 0, 1, 1, 0, 0, 1 ]
NCT02080221
30:40:cancer,73:82:treatment,,134:147:cancer,164:179:cancer
patients with an early stage malignancy that is not expected to require treatment in the next 2 years (such as early stage, resected breast cancer or asymptomatic prostate cancer)
2
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NCT02056873
42:45:treatment
(Subjects not required to participate in HRT but it will be highly encouraged, and must be completed prior to start of this study's protocol
2
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NCT02533674
22:30:treatment
Prior treatment with PM060184
2
[ "Prior", "treatment", "with", "PM060184" ]
[ 0, 0, 0, 1 ]
NCT02585973
,69:78:treatment,80:97:treatment,101:122:treatment
Receiving or less than 21 days since receiving any other concurrent cytotoxic, biologic agent(s) or investigational agent
2
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[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 1, 0, 0, 0, 0, 1, 1 ]
NCT01465100
1:13:treatment
Liver biopsy shows significant fibrosis, defined by the Ishak Stage 5
2
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[ 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01453088
1:18:chronic_disease
Organ dysfunction
2
[ "Organ", "dysfunction" ]
[ 2, 2 ]
NCT02007239
38:52:treatment,
Previous administration of any other biologic agent targeted at cytokine blockade within 5 days of enrollment
2
[ "Previous", "administration", "of", "any", "other", "biologic", "agent", "targeted", "at", "cytokine", "blockade", "within", "5", "days", "of", "enrollment" ]
[ 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT02242526
1:9:chronic_disease,,
Upper GI with a documented hiatal hernia greater than 5cm
2
[ "Upper", "GI", "with", "a", "documented", "hiatal", "hernia", "greater", "than", "5cm" ]
[ 2, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]
NCT01871727
13:42:chronic_disease
Significant pulmonary symptoms or disease
2
[ "Significant", "pulmonary", "symptoms", "or", "disease" ]
[ 0, 2, 2, 2, 2 ]
NCT01351103
1:40:chronic_disease,44:68:chronic_disease,116:127:treatment,169:175:chronic_disease,177:185:chronic_disease,187:195:chronic_disease,197:219:chronic_disease,221:242:treatment
Impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of oral LGK974 (e.g., ulcerative diseases, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome, small bowel resection)
2
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NCT00293475
56:66:treatment
cytology (analysis from cerebral spinal fluid [CSF] or vitrectomy)
2
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[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0 ]
NCT02408120
1:24:treatment
non-insulin injectables
2
[ "non-insulin", "injectables" ]
[ 1, 1 ]
NCT01686659
45:60:treatment
Adult patients undergoing one of the listed major surgeries associated with possibility of significant blood loss
2
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[ 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0 ]
NCT02551679
58:74:chronic_disease,121:137:treatment,195:215:treatment
Subjects who, in the opinion of the investigator, have a vascular disease prognosis that indicates they would require a major amputation in a time frame shortly after administration of the IMP (investigational drug or placebo)
2
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NCT02990481
1:16:chronic_disease
cardiac disease
2
[ "cardiac", "disease" ]
[ 2, 2 ]