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NCT00739362 | 42:49:chronic_disease | Personal or first-degree relative with a seizure history | 2 | [
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NCT02496208 | 12:37:chronic_disease,,,,,,131:165:treatment,156:165:treatment, | Concurrent uncontrolled hypertension defined as sustained blood pressure (BP) > 140 mmHg systolic, or > 90 mmHg diastolic despite optimal antihypertensive treatment within 7 days of the first dose of study treatment | 2 | [
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NCT03073070 | 1:14:chronic_disease | heart failure | 2 | [
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NCT02919436 | 12:19:allergy_name | Allergy to lactose | 2 | [
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NCT01815359 | 1:45:chronic_disease | Restrictive or obstructive pulmonary disease that would limit study compliance or place the patient at unacceptable risk for participation in the study | 2 | [
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NCT02561988 | 14:21:chronic_disease,50:73:treatment | History of a seizure disorder or requirement for anti-seizure medication | 2 | [
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NCT02135588 | 27:36:chronic_disease | Active clinically serious infection > CTCAE (version 4.03) Grade 2 | 2 | [
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NCT02056470 | 1:19:chronic_disease | sickle cell anemia | 2 | [
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NCT03117751 | ,34:60:cancer | LLy participants must have < 25% tumor cells in bone marrow and peripheral blood by morphology and flow cytometry | 2 | [
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NCT03016351 | 1:19:chronic_disease | multiple sclerosis | 2 | [
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NCT02347111 | ,20:24:treatment | Received 2 or more AADs in past | 2 | [
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NCT02844465 | 12:22:allergy_name | Allergy to gadolinium | 2 | [
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NCT03169881 | 1:30:chronic_disease | Congenital thrombotic disease | 2 | [
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NCT01445821 | 9:30:chronic_disease,, | Diffuse cutaneous scleroderma with involvement proximal to the elbow or knee and a Rodnan score (see Appendix V) of > 14 | 2 | [
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NCT01974609 | 32:63:chronic_disease | patients with other medical or psychological health conditions that preclude then from receiving either intervention or returning for follow-up visits | 2 | [
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NCT01530958 | 15:18:chronic_disease | Patients with CKD | 2 | [
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NCT02498951 | 7:16:chronic_disease,22:56:chronic_disease | Known infection with human immunodeficiency virus (HIV) | 2 | [
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NCT02382549 | 94:123:chronic_disease | Participants classified according to the New York Heart Association classification as having Class III or IV heart disease | 2 | [
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NCT02101736 | 1:23:chronic_disease | malabsorption syndrome | 2 | [
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NCT01553071 | 29:61:chronic_disease | Patients with an identified familial hyperlipidemia disorder | 2 | [
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NCT01811368 | 15:44:chronic_disease | Uncorrectable hepatic synthetic dysfunction evidenced by prolongation of the prothrombin time | 2 | [
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NCT02188121 | 1:14:chronic_disease,16:40:chronic_disease,42:58:chronic_disease,60:85:chronic_disease,90:99:chronic_disease | schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder, or psychosis NOS (chart diagnosis) | 2 | [
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NCT02338232 | 21:34:chronic_disease,45:61:chronic_disease,72:97:treatment,102:115:chronic_disease | Subjects with known heart failure, advanced renal impairment requiring renal replacement therapy, or liver failure | 2 | [
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NCT02536794 | 42:64:treatment, | Patients may not have received any other investigational agents within 4 weeks prior to registration | 2 | [
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NCT01894061 | 34:44:cancer,71:76:cancer,80:115:cancer,119:161:cancer,,,196:202:cancer,232:250:treatment | Patients must have no concurrent malignancy except curatively treated basal or squamous cell carcinoma of the skin or carcinoma in situ of the cervix and breast, adequately treated stage I or II cancer from which the patient is in complete remission | 2 | [
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NCT01964261 | 1:28:chronic_disease | High cervical spinal lesion | 2 | [
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NCT01931202 | 1:17:chronic_disease | Anxiety Disorder | 2 | [
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NCT02577406 | 71:100:allergy_name | Subject has known or suspected to have hypersensitivity to any of the components of study treatment | 2 | [
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NCT02555280 | ,53:75:treatment | More than two contiguous vertebral levels requiring surgical decompression | 2 | [
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NCT02030028 | 1:3:chronic_disease | RA diagnosis by American College of Rheumatology criteria | 2 | [
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NCT02465541 | 23:83:cancer,85:99:cancer,121:142:treatment,147:156:treatment | Previous diagnosis of grade 1 or 2, stage I or II endometrioid endometrial cancers (type I cancers) as confirmed during surgical intervention for treatment | 2 | [
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NCT03089853 | ,36:51:treatment | can be enrolled within 36 hours of hospitalization | 2 | [
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NCT01810588 | 35:71:cancer | Previously Relapsed or refractory acute leukemia (myeloid or lymphoid) | 2 | [
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NCT02312596 | 1:18:chronic_disease,, | Diabetes mellitus (type I or II) that is adequately controlled | 2 | [
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NCT01851694 | 1:31:treatment | Prior lung or liver transplant | 2 | [
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NCT03036098 | 1:16:treatment,25:33:treatment,35:44:treatment,46:55:treatment,57:67:treatment,72:91:treatment,146:167:treatment,171:190:treatment | Prior treatment with an anti-PD1, anti-PDL1, anti-PDL2, anti-CD137, or anti-CTLA4 antibody, or any other antibody or drug specifically targeting T-cell co-stimulation or checkpoint pathways | 2 | [
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NCT02470897 | 18:25:treatment,27:40:treatment,45:56:treatment,61:76:cancer | Previous radical surgery (prostatectomy) or cryosurgery for prostate cancer | 2 | [
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NCT03137771 | 43:56:treatment,78:86:treatment,106:124:chronic_disease,149:167:treatment,,197:212:treatment,214:238:treatment,243:266:treatment | Patients who received prior non-induction pembrolizumab, patients on chronic steroids or who have active autoimmune disease for which they received systemic treatment in the previous 2 years with corticosteroids, disease modifying agents, or immunosuppressive drugs | 2 | [
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NCT02453373 | 8:32:chronic_disease,44:46:chronic_disease,50:52:chronic_disease,80:91:chronic_disease,,,140:151:treatment | severe ventricular dysrhythmias (sustained VT or VF) ) which cause significant hypotension (SBP ≤ 120 mmHg requiring more than two pressor medications) | 2 | [
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NCT02016781 | 1:7:cancer,21:37:treatment,46:58:treatment,59:76:treatment, | Cancer treated with curative surgery without chemotherapy/radiation therapy > 5 years previously will be allowed | 2 | [
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NCT01989585 | ,152:180:treatment,189:197:chronic_disease,234:247:treatment,254:265:chronic_disease,266:280:chronic_disease,282:303:chronic_disease,305:317:chronic_disease,329:348:treatment | Unresolved toxicity of National Cancer Institute Common Terminology Criteria for Adverse Events, version 5.0 (NCI CTCAE v. 5.0) grade 2 or higher from previous anti-cancer therapy, except alopecia or an endocrine toxicity related to immunotherapy (e.g. thyroiditis/hypothyroidism, adrenal insufficiency, hypophysitis) re... | 2 | [
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NCT02442102 | ,48:68:chronic_disease | Unable to understand or speak English due to a cognitive impairment | 2 | [
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NCT02987491 | 1:10:allergy_name | Lidocaine allergy | 2 | [
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NCT02334865 | 27:38:allergy_name,40:52:allergy_name,54:85:allergy_name,90:147:allergy_name | Known hypersensitivity to thalidomide, lenalidomide, Keyhole Limpet Hemocyanin (KLH), or granulocyte colony-macrophage stimulating factor (GM-CSF) | 2 | [
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NCT02128906 | 1:10:treatment | cetuximab may be harmful to the fetus or the nursing infant | 2 | [
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NCT00630253 | 15:17:chronic_disease,46:66:chronic_disease,74:104:cancer,143:168:chronic_disease | Patients with FA must have moderately severe aplastic anemia (AA), early myelodysplastic syndrome (MDS) with no excess blasts with or without chromosomal abnormalities | 2 | [
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NCT01042522 | 34:55:cancer,79:103:cancer,152:162:cancer, | Patients with a history of other invasive malignancies, with the exception of non-melanoma skin cancer, are excluded if there is any evidence of other malignancy being present within the last five years | 2 | [
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NCT01697293 | 10:22:treatment,24:35:treatment,51:70:treatment,78:88:treatment,92:102:treatment,106:125:treatment,136:146:cancer | No prior chemotherapy, irradiation, or definitive therapeutic surgery (e.g., mastectomy or lumpectomy or axillary dissection) for this malignancy | 2 | [
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NCT02244814 | 1:13:chronic_disease,15:28:chronic_disease,30:44:chronic_disease,46:67:chronic_disease,69:81:chronic_disease,83:90:treatment,107:119:chronic_disease,121:139:chronic_disease,144:175:chronic_disease | hypertension, renal disease, thrombophilias, rheumatologic disease, preeclampsia, steroid use, history of pancreatitis, infectious disease, or intrauterine growth restriction | 2 | [
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NCT02213289 | 27:54:treatment,47:54:treatment,59:70:treatment,75:96:cancer, | Patients who have started first line mFOLFOX6 therapy (+/-trastuzumab for HER2 amplified tumors) may be considered for trial participation if they have received no more than 4 doses of therapy at the time of consent and screening | 2 | [
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NCT01774019 | 23:40:cancer,49:90:cancer,101:122:cancer | Diagnosis of probable pancreatic cancer, distal common bile duct (CBD) cholangiocarcinoma and other periampullary cancers (histology not required) | 2 | [
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NCT00107289 | ,48:64:treatment | At least 2 weeks should have elapsed since any biologic therapy | 2 | [
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NCT02791646 | 1:21:chronic_disease | cognitive impairment | 2 | [
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NCT02122185 | 19:43:treatment,65:86:treatment,108:134:treatment,144:152:treatment,161:175:cancer,179:192:treatment,196:224:treatment | Subjects for whom neoadjuvant chemotherapy followed by interval cytoreductive surgery is planned must have fine needle aspirate (FNA) or other cytology showing adenocarcinoma OR core biopsies OR surgically directed biopsies showing adenocarcinoma | 2 | [
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NCT03022292 | 1:39:chronic_disease | Prior retinal pigment epithelial (RPE) tear in study eye | 2 | [
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NCT01494662 | 53:83:chronic_disease | In cohort 4, eligible patients must have measurable Central Nervous System disease | 2 | [
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NCT02133196 | 1:8:cancer,37:62:treatment,,107:116:treatment | Lesions that have been treated with stereotactic radiosurgery must be clinically stable for 1 month after treatment for the patient | 2 | [
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NCT02531880 | 1:15:chronic_disease | Claustrophobia to a degree that the subject would feel uncomfortable in the MRI machine | 2 | [
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NCT02703272 | 26:35:treatment | has taken any disallowed therapies as noted in Section 8.2 | 2 | [
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NCT02106052 | 1:9:chronic_disease,,,, | Dementia based on a definition validated in people with MS using the MACFIMS (> 2 SD below the mean on at least one memory test and > 2 SD below the mean on at least one neuropsychological test in another domain) | 2 | [
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NCT02172651 | 25:35:chronic_disease,168:179:chronic_disease,183:184:chronic_disease,205:220:treatment | Participants with these infections are ineligible because they are at increased risk of significant complications in the perioperative period, particularly for active hepatitis B or C patients undergoing liver resection | 2 | [
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NCT02584309 | 1:36:treatment | Prior treatment with anthracyclines | 2 | [
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NCT02207439 | 1:19:cancer | Distant metastases | 2 | [
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NCT01459107 | 58:79:chronic_disease,84:95:chronic_disease,131:161:chronic_disease,167:180:chronic_disease | Conditions that may impact functional outcomes including Lipopolysaccharidosis and amyloidosis (may impact nerve regeneration) or rare disorders of bone healing like osteopetrosis | 2 | [
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NCT02497300 | 1:4:chronic_disease,,,,, | CKD (eGFR 25-60 mL/min/1.73m2) with urine albumin-to-creatinine ratio > 30 mg/g | 2 | [
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