DOI stringlengths 13 47 | Year int64 2.01k 2.02k | Journal stringlengths 3 170 | Title stringlengths 1 281 ⌀ | Abstract stringlengths 14 62.9k ⌀ | Full Text stringlengths 22 5M |
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10. 7759/cureus. 58564 | 2,024 | Cureus | Dry Mouth Dilemma: A Comprehensive Review of Xerostomia in Complete Denture Wearers | Xerostomia, commonly known as dry mouth, presents a significant challenge for individuals wearing complete dentures, affecting their oral health and quality of life. This review explores the relationship between saliva and complete dentures, highlighting the varied management strategies for xerostomia. Saliva plays a c... | Introduction and background The presence of optimal salivary flow, consistency, and composition holds importance, particularly in completely edentulous patients. It is imperative for the prosthodontist to meticulously consider these salivary characteristics throughout the stages of denture fabrication from initial asse... |
10. 7759/cureus. 58572 | 2,024 | Cureus | Exploring the Horizons of Four-Dimensional Printing Technology in Dentistry | In dentistry, the integration of additive manufacturing, particularly 3D printing, has marked significant progress. However, the emergence of 4D printing, which allows materials to change shape dynamically in response to stimuli, opens up new avenues for innovation. This review sheds light on recent advancements and po... | Introduction and background Exploring the dimensions: an introduction to 4D printing technology 4D printing denotes an additive manufacturing modality characterized by the fabrication of objects utilizing materials endowed with the capacity for self-metamorphosis or morphological adjustment in reaction to external stim... |
10. 7759/cureus. 58664 | 2,024 | Cureus | Synthesis and Analysis of Novel Hyaluronic Acid-Based Dual Photocrosslinkable Tissue Adhesive: An In Vitro Study | Background Tissue adhesives are mainly used for aiding in the attachment of adjacent tissues or to nearby hard tissue surfaces. They promote the natural healing processes of the tissues, especially for less painful closure, simple application, no need for sutures following surgery, and localized drug release. This stud... | Introduction Tissue adhesives are one of the most rapidly developing medical advances in recent times. It is one of the medical innovations that has developed most quickly in recent years [ 1 ]. Tissue adhesive, also known as surgical adhesive or medical glue, is a type of adhesive used in medicine and surgery to close... |
10. 7759/cureus. 58701 | 2,024 | Cureus | Exploration of Whitlockite Nanostructures for Hemostatic Applications | Background Calcium magnesium phosphate (CMP)-based whitlockite is a promising biomaterial for hemostasis and regenerative applications. Regenerative approaches aim to advance tissue repair and recovery in different clinical scenarios. Whitlockite is a biocompatible and biodegradable mineral that has garnered impressive... | Introduction Mineral apatite is a crystalline form of calcium phosphate and is a naturally occurring hydroxyapatite. It is the primary mineral in mammalian bones and teeth, giving those structures their strength and rigidity. Ca 5 (PO 4 ) 3 (OH) is the chemical formula for hydroxyapatite, which is made up of atoms of c... |
10. 7759/cureus. 59202 | 2,024 | Cureus | Green Synthesis and the Evaluation of Osteogenic Potential of Novel Europium-Doped-Monetite Calcium Phosphate by Cissus quadrangularis | Background The quest for an ideal bone grafting material has been ongoing for decades. Calcium phosphate, alone or in combination with other materials in natural bone, has been shown to aid in bone regeneration effectively. Monetite exhibits superior solubility and resorption rates among calcium phosphates, rendering i... | Introduction Enormous progress has been made in bone regeneration to bring an alternative to autologous grafts, as autologous grafts are associated with disadvantages such as limited availability and morbidity to the patient. Numerous techniques have been used routinely with biomaterials such as allografts, xenografts,... |
10. 7759/cureus. 5938 | 2,019 | Cureus | Immunotherapy – Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites | Immunotherapy is widely regarded to have the ability to transform the treatment of cancer, with immune checkpoint inhibitors already in use for cancers such as advanced melanoma and non-small cell lung cancer (NSCLC). However, despite its potential, the widespread adoption of immunotherapy for the treatment of other ca... | Introduction and background The notion of harnessing the host’s immune system to eliminate cancer has been well-established for years, even though the field has only started taking off relatively recently. It stems from the knowledge that the immune system is a critical player in the prevention, as well as the developm... |
10. 7759/cureus. 59474 | 2,024 | Cureus | Stem Cell Therapy for Myocardial Infarction and Heart Failure: A Comprehensive Systematic Review and Critical Analysis | In exploring therapeutic options for ischemic heart disease (IHD) and heart failure, cell-based cardiac repair has gained prominence. This systematic review delves into the current state of knowledge surrounding cell-based therapies for cardiac repair. Employing a comprehensive search across relevant databases, the stu... | Introduction and background Ischemic heart disease (IHD) is a significant worldwide health problem, resulting in 17. 9 million fatalities per year [ 1, 2 ]. Despite recent improvements in treatment, a significant number of individuals still experience persistent ischemia and congestive heart failure (CHF). Despite the ... |
10. 7759/cureus. 59848 | 2,024 | Cureus | Fabrication of Periodontal Membrane From Nelumbo nucifera: A Novel Approach for Dental Applications | Background The periodontal membrane plays a crucial role in tooth support and maintenance. Natural materials with biocompatible and bioactive properties are of interest for periodontal membrane fabrication. Nelumbo nucifera, known for its therapeutic properties, presents a potential source for such materials. Aim This ... | Introduction Nelumbo nucifera, commonly referred to as lotus, is an aquatic perennial plant that falls within the Nelumbonaceae family. This plant serves as a valuable source of herbal medicine, exhibiting potent antipyretic, cooling, astringent, and demulcent properties. The seeds of the lotus plant are utilized in th... |
10. 7759/cureus. 59924 | 2,024 | Cureus | Comparative Analysis of the Effectiveness of Four Distinct Remineralizing Agents in Artificial White Spot Lesions Following Chitosan Nanoparticle Pretreatment: An In Vitro Study | Aim The aim of the study was to compare the effectiveness of chitosan nanoparticle pretreatment with four different remineralizing agents in artificial white spot lesions. Methods A total of 100 human maxillary first premolars were selected and divided into five groups of 20 samples in each group. Artificial white spot... | Introduction Dental caries is one of the most common dental diseases and is recognized as a leading cause of tooth loss [ 1 ]. Fluoride has previously been used for caries treatment due to its cariostatic potential [ 2 ]. However, certain limitations (such as dental and skeletal fluorosis) have restricted its use. Rese... |
10. 7759/cureus. 59970 | 2,024 | Cureus | The Use of Platelet-Rich Plasma and Stem Cell Injections in Musculoskeletal Injuries | Injuries to the musculoskeletal (MSK) system can have a significant impact on an individual’s activities of daily living, as this multifunctional unit is associated with physical movement. Treatment of MSK injuries often involves corticosteroid injections, supplements, pharmaceutical agents, and/or surgery. While these... | Introduction and background The musculoskeletal (MSK) system is a dynamic and multifunctional unit of the human body that is composed of bones, cartilage, ligaments, connective tissue, and tendons, which function to support the body and aid in physical movement. As such, injuries to the MSK system, including acute musc... |
10. 7759/cureus. 60201 | 2,024 | Cureus | Enhancing Hip Arthroplasty Outcomes: The Multifaceted Advantages, Limitations, and Future Directions of 3D Printing Technology | In the evolving field of orthopedic surgery, the integration of three-dimensional printing (3D printing) has emerged as a transformative technology, particularly in addressing the rising incidence of degenerative joint diseases. The integration of 3D printing technology in hip arthroplasty offers substantial advantages... | Introduction and background In the dynamic landscape of modern medicine and surgery, the evolution of technology has propelled the field into new frontiers of innovation. One advancement is the application of three-dimensional printing (3DP) - a transformative technology with far-reaching implications, particularly in ... |
10. 7759/cureus. 892 | 2,016 | Cureus | Biological Treatment Approaches for Degenerative Disc Disease: A Review of Clinical Trials and Future Directions | Biologic-based treatment strategies for musculoskeletal diseases have gained traction over the past 20 years as alternatives to invasive, costly, and complicated surgical interventions. Spinal degenerative disc disease (DDD) is among the anatomic areas being investigated among this group, notably due to its high incide... | Introduction and background The radiographic findings of degenerative disc disease (DDD) can be found in 40% of individuals younger than 30 and in more than 90% of individuals older than 50 years of age [ 1 - 2 ]. While the majority of these imaging findings are part of the normal aging process, a subset of patients wi... |
10. 7860/JCDR/2013/6915. 3638 | 2,013 | Journal of Clinical and Diagnostic Research : JCDR | A Natural Meliorate: Revolutionary Tissue Engineering in Endodontics | Platelet-Rich Fibrin (PRF) was first described by Choukroun et al. , (2001). It has been referred to as a second-generation platelet concentrate, which has been shown to have several advantages over traditionally prepared platelet-rich plasma. PRF has a physiologic architecture that is very favourable to the healing pr... | No full text available |
10. 7860/JCDR/2014/7609. 3937 | 2,014 | Journal of Clinical and Diagnostic Research : JCDR | Biomaterials in Tooth Tissue Engineering: A Review | Biomaterials play a crucial role in the field of tissue engineering. They are utilized for fabricating frameworks known as scaffolds, matrices or constructs which are interconnected porous structures that establish a cellular microenvironment required for optimal tissue regeneration. Several natural and synthetic bioma... | No full text available |
10. 7860/JCDR/2014/8257. 5034 | 2,014 | Journal of Clinical and Diagnostic Research : JCDR | Regenerative Endodontics: A Road Less Travelled | Although traditional approaches like root canal therapy and apexification procedures have been successful in treating diseased or infected root canals, but these modalities fail to re-establish healthy pulp tissue in treated teeth. Regeneration-based approaches aims to offer high levels of success by replacing diseased... | No full text available |
10. 7860/JCDR/2015/13907. 6565 | 2,015 | Journal of Clinical and Diagnostic Research : JCDR | Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review | Biopolymers provide a plethora of applications in the pharmaceutical and medical applications. A material that can be used for biomedical applications like wound healing, drug delivery and tissue engineering should possess certain properties like biocompatibility, biodegradation to non-toxic products, low antigenicity,... | No full text available |
10. 7860/JCDR/2015/9871. 5636 | 2,015 | Journal of Clinical and Diagnostic Research : JCDR | SHED - Basic Structure for Stem Cell Research | The discovery that stem cells from dental pulp are capable of differentiating into endothelial cells raised the exciting possibility that these cells can be a single source of odontoblasts and vascular networks in dental tissue engineering. These so-called mesenchymal stem cell populations have been identified from hum... | No full text available |
10. 7860/JCDR/2016/16809. 7901 | 2,016 | Journal of Clinical and Diagnostic Research : JCDR | Test Tube Tooth: The Next Big Thing | Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the field of prosthetic dentistry, it would be ideal to recreate a third se... | No full text available |
10. 9734/BBJ/2013/4309 | 2,014 | British biotechnology journal | Constraining the Pluripotent Fate of Human Embryonic Stem Cells for Tissue Engineering and Cell Therapy – The Turning Point of Cell-Based Regenerative Medicine | To date, the lack of a clinically-suitable source of engraftable human stem/progenitor cells with adequate neurogenic potential has been the major setback in developing safe and effective cell-based therapies for regenerating the damaged or lost CNS structure and circuitry in a wide range of neurological disorders. Sim... | 1. INTRODUCTION Pluripotent human embryonic stem cells (hESCs) have both the unconstrained capacity for long-term stable undifferentiated growth in culture and the intrinsic potential for differentiation into all somatic cell types in the human body, holding tremendous potential for restoring human tissue and organ fun... |
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