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Datasets Included

5 disease-specific bulk RNA-seq datasets, each containing 200 samples aggregated from public GEO repositories.

obs (samples / observations)

Each row is one bulk RNA-seq sample with 4 metadata columns:

Column Description
tissue Biological tissue from which RNA was extracted
disease Disease condition of the sample
sample_id Individual GEO sample identifier (GSM...)
dataset_name GEO series the sample belongs to (GSE...)

vars (features / genes)

Each column is a gene, identified by:

  • index (gene_names): Entrez gene ID (numeric string, e.g. "1", "10", "100")
  • gene_symbols: HGNC symbol (e.g. A1BG, NAT2, ADA)
  • gene_names: same as index (Entrez ID repeated)

The expression matrix X is bulk RNA-seq gene expression (samples × genes) in raw FPKM (Fragments Per Kilobase of transcript per Million mapped reads), without further normalization

Crohn Disease (CD) : Ileum

Colitis, Ulcerative (UC) : Colon (multiple segments)

Dermatitis, Atopic (AD) : Skin

Diabetes Mellitus, Type 1 (T1D) : Whole Blood

Psoriasis (PSO) : Skin

Each dataset covers one immune-mediated inflammatory disease, with samples drawn from the disease-relevant tissue.

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