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QA:9ac5d11a2a316d649ec8a304
QAG:8ee7af7d38d36ca6c684b5a5
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "However, the overall survival (OS) associated with first-line treatments is less than one year, and that associated with second-line treatments is shorter at only 6-8 months, suggesting that the chemotherapy regimens for advanced ESCC may have achieved a bottleneck ( 1...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:20862e17546d7a6df806745c","quotes":["However, the overall survival (OS) associated with first-line treatments is ...
[ "CLM:20862e17546d7a6df806745c", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10185849" ]
[ "SPAN:8c8484f09d0b47fbf9e1ca74" ]
[]
[]
{"qa_id":"QA:9ac5d11a2a316d649ec8a304","qa_group_id":"QAG:8ee7af7d38d36ca6c684b5a5","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"However, the overall survival (OS) associated with first-line trea...
QA:9e822a0beaf54994c7f388f0
QAG:9a97b0c2e5ccab3cc55585ba
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Stage IVB ESCC patients who had failed first-line immunochemotherapy received primary tumor radiotherapy (40GY/20F)/metastatic lesions radiotherapy (30GY/10F) combined with Camrelizumab and irinotecan achieved an ORR of 40.8%, a DCR of 75.5%, with median PFS and OS of ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b8161162944e452f80336565","quotes":["Stage IVB ESCC patients who had failed first-line immunochemotherapy receive...
[ "CLM:b8161162944e452f80336565", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:ba9785b6444fe128a8f3bf11" ]
[]
[]
{"qa_id":"QA:9e822a0beaf54994c7f388f0","qa_group_id":"QAG:9a97b0c2e5ccab3cc55585ba","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Stage IVB ESCC patients who had failed first-line immunochemothera...
QA:9f090d7f6765dff3fd1b859d
QAG:721d1d22197929ec30301e56
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "This study aims to evaluate the safety and effectiveness of camrelizumab combined with chemotherapy in the neoadjuvant treatment of ESCC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c456404a1119da266ce37773","quotes":["This study aims to investigate the safety and effectiveness of camrelizumab ...
[ "CLM:c456404a1119da266ce37773", "CLM:271ef2ae6ac25da19ecda350" ]
[ "PMCID:PMC9577786" ]
[ "SPAN:54a097c7a006ee757a34ec0b" ]
[]
[]
{"qa_id":"QA:9f090d7f6765dff3fd1b859d","qa_group_id":"QAG:721d1d22197929ec30301e56","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"This study aims to evaluate the safety and effectiveness of camrel...
QA:9f4287c8da33ddb2860d454a
QAG:988d0d299a00989ede182485
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "NLR level at baseline was increased in patients with ESCC when compared with tumor-free people, therefore we calculated PLR, MLR and SII in general population to assess the influence of tumor on alteration of PLR, MLR and SII (Table 6 )"? Return the original wording wi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:eaaafc170797b1cc5c31b103","quotes":["NLR level at baseline was increased in patients with ESCC when compared with...
[ "CLM:eaaafc170797b1cc5c31b103", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8262036" ]
[ "SPAN:e6f30feef51549f9cbe18e8f" ]
[]
[]
{"qa_id":"QA:9f4287c8da33ddb2860d454a","qa_group_id":"QAG:988d0d299a00989ede182485","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"NLR level at baseline was increased in patients with ESCC when com...
QA:a0c0bd75925d15b483632877
QAG:1e80fcfc2687cfe60fc7aa3b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "trial participants in the PD-1 inhibitor arm received anti-PD-1 agent only, while participants in the chemotherapy arm received conventional chemotherapy regimen; and the trial used at least three of the following (OS, progression-free survival [PFS], objective respons...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a4481111b1828f6dbd510d4","quotes":["Studies eligible for the analyses satisfied each of the following requiremen...
[ "CLM:9a4481111b1828f6dbd510d4", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8579527" ]
[ "SPAN:947e310371175820538cead3" ]
[]
[]
{"qa_id":"QA:a0c0bd75925d15b483632877","qa_group_id":"QAG:1e80fcfc2687cfe60fc7aa3b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"trial participants in the PD-1 inhibitor arm received anti-PD-1 ag...
QA:a18057de92226f2b346961ba
QAG:2134a99a2ea88e008ffa3e4a
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Patients received camrelizumab at different dose levels, including three, 64 and two patients receiving a dose of 60, 200 and 400 mg every 2 weeks, respectively"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requir...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:384ff643aa3419ab7398b368","quotes":["A total of 69 patients with advanced ESCC enrolled in our center were consec...
[ "CLM:384ff643aa3419ab7398b368", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9161342" ]
[ "SPAN:4d2992a79391d13bb675a64c" ]
[]
[]
{"qa_id":"QA:a18057de92226f2b346961ba","qa_group_id":"QAG:2134a99a2ea88e008ffa3e4a","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Patients received camrelizumab at different dose levels, including...
QA:a1b914f3749cee684c175fa2
QAG:bb77a75506f36336c9a9b712
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Overall, a high enrichment score of the TREM2 + TAMs gene signature predicted poor OS and PFS and was associated with potential immunotherapy modulation"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4df10b4f9a49b50b91130530","quotes":["In addition, we collected 10 samples from ESCC patients treated with immunot...
[ "CLM:4df10b4f9a49b50b91130530", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC10175681" ]
[ "SPAN:2cf2acf2640f64a604aaae7c" ]
[]
[]
{"qa_id":"QA:a1b914f3749cee684c175fa2","qa_group_id":"QAG:bb77a75506f36336c9a9b712","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Overall, a high enrichment score of the TREM2 + TAMs gene signatur...
QA:a1dd1905b7cd35d4a88d9d74
QAG:ee1de31f36beb0803ffa83f9
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In a similar phase Ib study, 20 locally advanced ESCC patients treated with radiotherapy plus Camrelizumab achieved an ORR of 74%, with a median OS and progression-free survival (PFS) of 16.7 and 11.7 months, respectively, and 24-month OS and PFS rates of 31.6% and 35....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fc46e1f450fd1368e6576630","quotes":["In a similar phase Ib study, 20 locally advanced ESCC patients treated with ...
[ "CLM:fc46e1f450fd1368e6576630", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:0ffcf926c03c97c271bb3d6a" ]
[]
[]
{"qa_id":"QA:a1dd1905b7cd35d4a88d9d74","qa_group_id":"QAG:ee1de31f36beb0803ffa83f9","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In a similar phase Ib study, 20 locally advanced ESCC patients tre...
QA:a48a9ca00261508490421bd5
QAG:1422406cc9d205915e5e71ad
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "The combination of PD-1 inhibitors with TP or CF improved OS compared with chemotherapy alone, and there were no significant differences between the CF group and TP group (P = 0.499), demonstrating that both chemotherapy regimens can be combined with immunotherapy for ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:57eacf04ca515b6db9964b37","quotes":["The combination of PD-1 inhibitors with TP or CF significantly improved OS c...
[ "CLM:57eacf04ca515b6db9964b37", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC10185849" ]
[ "SPAN:4f392a90fe9847ca664b56e7" ]
[]
[]
{"qa_id":"QA:a48a9ca00261508490421bd5","qa_group_id":"QAG:1422406cc9d205915e5e71ad","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"The combination of PD-1 inhibitors with TP or CF improved OS compa...
QA:a5a83b6528e274263889128d
QAG:6b2503ee60171d229a2eeba2
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "We have previously reported that the presence of TLSs around gastric cancer is associated with a good prognosis, that increased granzyme B and perforin expression is observed around TLSs, and that memory T cells are present around TLSs"? Return the original wording wit...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c96b9373ac4693053d2672fe","quotes":["We have previously reported that the presence of TLSs around gastric cancer ...
[ "CLM:c96b9373ac4693053d2672fe", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9233387" ]
[ "SPAN:45a2a8f4c82bf35ae7a0103b" ]
[]
[]
{"qa_id":"QA:a5a83b6528e274263889128d","qa_group_id":"QAG:6b2503ee60171d229a2eeba2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"We have previously reported that the presence of TLSs around gastr...
QA:a5b543cdec61b59fb258fa5a
QAG:ea61d5bea3a3e7bf0ade721e
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In recent years, several studies have reported that nCT combined with ICIs followed by esophagectomy could be recognized as an effective treatment for locally advanced ESCC, and the pCR could be increased to 25%-39.2% ( 24 – 27 )"? Return the original wording with pape...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:801c1b16ef7c48edd1f326f3","quotes":["In recent years, several studies have reported that nCT combined with ICIs f...
[ "CLM:801c1b16ef7c48edd1f326f3", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9585292" ]
[ "SPAN:21d1aceb2c38b9749c07f3e9" ]
[]
[]
{"qa_id":"QA:a5b543cdec61b59fb258fa5a","qa_group_id":"QAG:ea61d5bea3a3e7bf0ade721e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In recent years, several studies have reported that nCT combined w...
QA:a8e469da8f1134823c0637be
QAG:f7e691d45534acf8f8bbf844
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Nevertheless, in our cohort of patients, the neoadjuvant setting, camrelizumab combined with chemotherapy led to good survival outcomes, as well as high rates of MPR and pCR, among patients with locally advanced ESCC"? Return the original wording with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b0325298176d99156af0d2a1","quotes":["Nevertheless, in our cohort of patients, the neoadjuvant setting, camrelizum...
[ "CLM:b0325298176d99156af0d2a1", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9251418" ]
[ "SPAN:9ff32b37d3cc9eaebf333ee9" ]
[]
[]
{"qa_id":"QA:a8e469da8f1134823c0637be","qa_group_id":"QAG:f7e691d45534acf8f8bbf844","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Nevertheless, in our cohort of patients, the neoadjuvant setting, ...
QA:a985487267f9d8df1eed0484
QAG:64ae336d88fca3670a7fe7d7
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Patients and Methods Patients with LA-ESCC who received nICT followed by surgery from Jun 2019 to Dec 2021 were enrolled and randomly divided into two sets (7:3)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:e44c1161a94a0c69b1e2a4bd","quotes":["Patients and Methods Patients with LA-ESCC who received nICT followed by sur...
[ "CLM:e44c1161a94a0c69b1e2a4bd", "CLM:08adec9d2dfaf31bc5d24f84" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:e122466691681ae1b0194be5" ]
[]
[]
{"qa_id":"QA:a985487267f9d8df1eed0484","qa_group_id":"QAG:64ae336d88fca3670a7fe7d7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Patients and Methods Patients with LA-ESCC who received nICT follo...
QA:aca4dd1434484901a00f6618
QAG:d7c84f0d4c2fa40d0adf6727
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Despite the TCGA database showing that high TREM2 , SPP1 , APOE , C1QC , C1QB , and C1QA expression led to poor OS, the roles of these genes in ESCC remain unclear"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance req...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4eb5bcb0a874c4f497a78fb7","quotes":["Despite the TCGA database showing that high TREM2 , SPP1 , APOE , C1QC , C1Q...
[ "CLM:4eb5bcb0a874c4f497a78fb7", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10175681" ]
[ "SPAN:4462886dc46ef8fdb066f973" ]
[]
[]
{"qa_id":"QA:aca4dd1434484901a00f6618","qa_group_id":"QAG:d7c84f0d4c2fa40d0adf6727","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Despite the TCGA database showing that high TREM2 , SPP1 , APOE , ...
QA:ad865a4dfe49319b20daf49b
QAG:11bb4096e9a47fff0d347b72
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "For locally advanced resectable ESCC, adding immunotherapy to standard care of the neoadjuvant chemoradiotherapy followed by surgery has not increased the pCR rate but has increased toxicity to some extent"? Return the original wording with paper, Claim, and Evidence S...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c0099aca0f18af9f125b355a","quotes":["For locally advanced resectable ESCC, adding immunotherapy to standard care ...
[ "CLM:c0099aca0f18af9f125b355a", "CLM:2a0dc33e26036765ea69bb10" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:5296239b0e6a815d33da6e01" ]
[]
[]
{"qa_id":"QA:ad865a4dfe49319b20daf49b","qa_group_id":"QAG:11bb4096e9a47fff0d347b72","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"For locally advanced resectable ESCC, adding immunotherapy to stan...
QA:ae498ce8078c70804edf1cb0
QAG:8617bedf0fa0ccd0c5f913ff
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "All patients were histologically confirmed locally advanced ESCC, which was defined as cT1N1-3M0 or cT2-4aN0-3M0 (AJCC, 8th Edition) based on contrast increased computerized tomography (CT), and/or magnetic resonance imaging (MRI), upper gastrointestinal endoscopic ult...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:671d39d28baa1cfc8030adf3","quotes":["All patients were histologically confirmed locally advanced ESCC, which was ...
[ "CLM:671d39d28baa1cfc8030adf3", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9251418" ]
[ "SPAN:9d9c627691ae94061e02ed09" ]
[]
[]
{"qa_id":"QA:ae498ce8078c70804edf1cb0","qa_group_id":"QAG:8617bedf0fa0ccd0c5f913ff","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"All patients were histologically confirmed locally advanced ESCC, ...
QA:b21e7e3351bec5872e9bf096
QAG:e3b0c5281e866e96a7601487
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Compared with chemotherapy alone, chemo-immunotherapy improved the OS of ESCC patients (pooled HR=0.69; 95% CI, 0.63–0.76; p<0.01)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact suppo...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5b77bb88a4c4a4e3059b6c01","quotes":["Compared with chemotherapy alone, chemo-immunotherapy significantly improved...
[ "CLM:5b77bb88a4c4a4e3059b6c01", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:68d4829f62eab273c5d5ad1f" ]
[]
[]
{"qa_id":"QA:b21e7e3351bec5872e9bf096","qa_group_id":"QAG:e3b0c5281e866e96a7601487","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Compared with chemotherapy alone, chemo-immunotherapy improved the...
QA:b38218a7c8d5325ca3d81fea
QAG:14dfeb08495136e977309204
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "This study aims to evaluate the prediction efficacy of pre-therapeutic CT imaging based radiomics models in treatment response of patients with advanced ESCC receiving anti-PD-1 antibodies plus chemotherapy"? Return the original wording with paper, Claim, and Evidence ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:350aa98892765ca25e7ae951","quotes":["This study aimed to evaluate the prediction efficacy of pre-therapeutic CT i...
[ "CLM:350aa98892765ca25e7ae951", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8557514" ]
[ "SPAN:32049d0c34b0b26f3650b2f3" ]
[]
[]
{"qa_id":"QA:b38218a7c8d5325ca3d81fea","qa_group_id":"QAG:14dfeb08495136e977309204","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"This study aims to evaluate the prediction efficacy of pre-therape...
QA:b41559bff24bf6ec379fad74
QAG:e09c2f21ac284cfcb59ffc64
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Conclusion Second line PD-1 inhibitors improved the OS and ORR of patients with advanced ESCC, especially the OS of those with positive PD-L1 expression, and did not result in significant improvement in PFS and DCR"? Return the original wording with paper, Claim, and E...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c58065dc07a58847e1d42e76","quotes":["Conclusion Second line PD-1 inhibitors significantly improved the OS and ORR...
[ "CLM:c58065dc07a58847e1d42e76", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8579527" ]
[ "SPAN:c23a41e97b0ea1be5992225a" ]
[]
[]
{"qa_id":"QA:b41559bff24bf6ec379fad74","qa_group_id":"QAG:e09c2f21ac284cfcb59ffc64","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Conclusion Second line PD-1 inhibitors improved the OS and ORR of ...
QA:b45656ba1707ea3f46f7eff9
QAG:1b1e141b188bb3906e796846
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Several studies have shown that PD-1 inhibitors plus chemotherapy prolonged survival for patients with advanced ESCC ( 20 – 25 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact support...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:230010b55d8fa314c138f186","quotes":["Several studies have shown that PD-1 inhibitors plu...
[ "CLM:230010b55d8fa314c138f186", "CLM:08a48a247c9286d56048a968", "CLM:47163ecffcf8a1593d4b37fa" ]
[ "PMCID:PMC9098952", "PMCID:PMC9428701" ]
[ "SPAN:67602ea38a816048a7f33d05", "SPAN:41a424d8ad80b9cfb678d3be" ]
[ "ASC2:22dae31d277080756ef7b9f8" ]
[]
{"qa_id":"QA:b45656ba1707ea3f46f7eff9","qa_group_id":"QAG:1b1e141b188bb3906e796846","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Several studies have shown that PD-1 inhibitors plus chemotherapy ...
QA:b5db57a22165df0552e2c173
QAG:a263a5be86d6f0d6e5c56dff
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "This study aims to evaluate the efficacy and safety of immune checkpoint inhibitor treatment in esophageal squamous cell carcinoma"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact suppo...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7491c210b1a002a124d5e6d1","quotes":["This study aimed to investigate the efficacy and safety of immune checkpoint...
[ "CLM:7491c210b1a002a124d5e6d1", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC8724211" ]
[ "SPAN:9c6abce7ecd59cd02c0f3022" ]
[]
[]
{"qa_id":"QA:b5db57a22165df0552e2c173","qa_group_id":"QAG:a263a5be86d6f0d6e5c56dff","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"This study aims to evaluate the efficacy and safety of immune chec...
QA:b6395bb21a2ae65175261293
QAG:4a4bc47735d02f8342f1cd5b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "The clinical proteomic tumor analysis consortium (CPTAC) data also suggest that decreased protein level of β ‐TrCP exists in other cancer types, including breast invasive carcinoma, colon adenocarcinoma, and glioblastoma (GBM) (Figure S1A , Supporting Information)"? Re...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ed1b1ec661f1edc4c89a9c65","quotes":["However, at the protein level, β ‐TrCP expressed at lower level in ESCC tiss...
[ "CLM:ed1b1ec661f1edc4c89a9c65", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC10238178" ]
[ "SPAN:b9884cc81b334539931e7f81" ]
[]
[]
{"qa_id":"QA:b6395bb21a2ae65175261293","qa_group_id":"QAG:4a4bc47735d02f8342f1cd5b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"The clinical proteomic tumor analysis consortium (CPTAC) data also...
QA:ba395eb91b4e90b798c2d9d9
QAG:aea098746e70212e068b062f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "668 § Normal albumin, n (%) 64 (100%) 32 (100%) 32 (100%) NA increased leucocyte, n (%) 10 (15.6%) 5 (15.6%) 5 (15.6%) 1.000 † C-reactive protein≥10 mg/L, n (%) 31 (48.4%) 13 (40.6%) 18 (56.3%) 0.211 † Underlying diseases, n (%) 21 (32.8%) 10 (31.3%) 11 (34.4%) 0.790 †...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dea79c43110a5a8fc7728e6d","quotes":["Table 1 Clinicopathological characteristics of advanced ESCC patients treate...
[ "CLM:dea79c43110a5a8fc7728e6d", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8557514" ]
[ "SPAN:ea273b8d1fac66e5d6f1eb24" ]
[]
[]
{"qa_id":"QA:ba395eb91b4e90b798c2d9d9","qa_group_id":"QAG:aea098746e70212e068b062f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"668 § Normal albumin, n (%) 64 (100%) 32 (100%) 32 (100%) NA incre...
QA:bcad7a7ac135ced55a6d17d9
QAG:7bb5d953e7842e9e7d641828
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "These changes have led to prolonged survival for ESCC patients, but questions remain which are challenging to answer in the context of single trial datasets"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requiremen...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:53533c49ce570418a2807de9","quotes":["These changes have led to prolonged survival for ESCC patients, but question...
[ "CLM:53533c49ce570418a2807de9", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8804258" ]
[ "SPAN:cd9d323d7f56ea39ad2ef6f2" ]
[]
[]
{"qa_id":"QA:bcad7a7ac135ced55a6d17d9","qa_group_id":"QAG:7bb5d953e7842e9e7d641828","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"These changes have led to prolonged survival for ESCC patients, bu...
QA:bd74bb1ddc78725268f529fd
QAG:7e8853f76e3e0321b891004d
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In ESCC patient‐derived xenograft (PDX) models, the inhibitory effect of ATRA on tumor growth was also observed, and the level of OTUD6B was correlated with β ‐TrCP and negatively correlated with SNAIL (Figure 6G,H and Figure S6B , Supporting Information)"? Return the ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9e570f363a68574a554557c5","quotes":["In ESCC patient‐derived xenograft (PDX) models, the inhibitory effect of ATR...
[ "CLM:9e570f363a68574a554557c5", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10238178" ]
[ "SPAN:ab04ebf758c90278df9985d0" ]
[]
[]
{"qa_id":"QA:bd74bb1ddc78725268f529fd","qa_group_id":"QAG:7e8853f76e3e0321b891004d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In ESCC patient‐derived xenograft (PDX) models, the inhibitory eff...
QA:be947e65e7ef2536223eefe3
QAG:e1c41e0024a8f9e74f0d0d13
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "11 However, there is a lack of studies regarding risk factors of pCR prediction in LA-ESCC patients who received nICT"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:baa29850fac2c86a8ababd41","quotes":["11 However, there is a lack of studies regarding risk factors of pCR predict...
[ "CLM:baa29850fac2c86a8ababd41", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:e6ff29ec276de32cbf7b2348" ]
[]
[]
{"qa_id":"QA:be947e65e7ef2536223eefe3","qa_group_id":"QAG:e1c41e0024a8f9e74f0d0d13","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"11 However, there is a lack of studies regarding risk factors of p...
QA:bf36aa69aae577eee9650ad9
QAG:1d1132cac030b9c3a48100bd
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Patients with advanced ESCC who received second or further-line treatment of anlotinib plus PD-1 blockade were grouped as cohort A (n=48), and those who received anlotinib monotherapy were grouped as cohort B (n=50)"? Return the original wording with paper, Claim, and ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:47163ecffcf8a1593d4b37fa","quotes":["Patients with advanced ESCC who received second or further-line treatment of...
[ "CLM:47163ecffcf8a1593d4b37fa", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9428701" ]
[ "SPAN:41a424d8ad80b9cfb678d3be" ]
[]
[]
{"qa_id":"QA:bf36aa69aae577eee9650ad9","qa_group_id":"QAG:1d1132cac030b9c3a48100bd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Patients with advanced ESCC who received second or further-line tr...
QA:bf4cc50971801cf8f424f8cd
QAG:c0b8a273f856f29ab145f569
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "For locally advanced unresectable ESCC, the addition of immunotherapy to definitive chemoradiotherapy during the concurrent or consolidation phase holds promise for improved long-term survival"? Return the original wording with paper, Claim, and Evidence Span reference...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:08adec9d2dfaf31bc5d24f84","quotes":["For locally advanced unresectable ESCC, the addition of immunotherapy to def...
[ "CLM:08adec9d2dfaf31bc5d24f84", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:d02eaa88bf26fc37054d90ff" ]
[]
[]
{"qa_id":"QA:bf4cc50971801cf8f424f8cd","qa_group_id":"QAG:c0b8a273f856f29ab145f569","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"For locally advanced unresectable ESCC, the addition of immunother...
QA:c07518d8a60c15fb6947848f
QAG:24c377e5efc5fa4666f6b20b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "The ESCORT randomized phase 3 study ( 14 ) showed that camrelizumab improved OS compared with chemotherapy as second-line therapy in Chinese patients with advanced ESCC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenanc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:81072385b58f887727eb7b87","quotes":["The ESCORT randomized phase 3 study ( 14 ) showed that camrelizumab improved...
[ "CLM:81072385b58f887727eb7b87", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8724211" ]
[ "SPAN:f002ae18d11a642e817fcd85" ]
[]
[]
{"qa_id":"QA:c07518d8a60c15fb6947848f","qa_group_id":"QAG:24c377e5efc5fa4666f6b20b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"The ESCORT randomized phase 3 study ( 14 ) showed that camrelizuma...
QA:c1f173cd2b984a9ccdf21eb6
QAG:029adb4d4b03aca22c19130e
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Moreover, co-culturing of PBMCs with an anticancer drug-treated esophageal squamous cell carcinoma cell line increased the CD20 and CD23 expression in PBMCs in vitro"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:88412ad9eca53f00a28e6610","quotes":["Moreover, co-culturing of PBMCs with an anticancer drug-treated esophageal s...
[ "CLM:88412ad9eca53f00a28e6610", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9233387" ]
[ "SPAN:942cbe17a04187abc18f3259" ]
[]
[]
{"qa_id":"QA:c1f173cd2b984a9ccdf21eb6","qa_group_id":"QAG:029adb4d4b03aca22c19130e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Moreover, co-culturing of PBMCs with an anticancer drug-treated es...
QA:c2a743fb9c6b69d9feac87d0
QAG:729b2ee844e125ec45ec4760
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Compared with chemotherapy alone, the incorporation of anti-programmed cell death-1 (PD-1) antibodies into chemotherapy has improved the prognosis of ESCC patients"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance req...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b95eb0dee0b66b44200ff790","quotes":["Compared with chemotherapy alone, the incorporation of anti-programmed cell ...
[ "CLM:b95eb0dee0b66b44200ff790", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:0ac47b6461f852f718fc1878" ]
[]
[]
{"qa_id":"QA:c2a743fb9c6b69d9feac87d0","qa_group_id":"QAG:729b2ee844e125ec45ec4760","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Compared with chemotherapy alone, the incorporation of anti-progra...
QA:c3fa462bbee57da530d85c5b
QAG:f87f18f4149df99e934a71bb
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In addition, adjuvant nivolumab improved disease-free survival (22.4 versus 11.0 months, hazard ratio (HR) 0.69) in esophageal cancer patients who received nCRT but had residual disease at the time of resection in the CheckMate-577 trial, with the greatest benefit seen...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f2133e79e163974bbccfe48d","quotes":["In addition, adjuvant nivolumab significantly improved disease-free survival...
[ "CLM:f2133e79e163974bbccfe48d", "CLM:0991831bbf7006fe9faffdbf" ]
[ "PMCID:PMC10427424" ]
[ "SPAN:b7d6012ae5ec4dbb4d96d43a" ]
[]
[]
{"qa_id":"QA:c3fa462bbee57da530d85c5b","qa_group_id":"QAG:f87f18f4149df99e934a71bb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In addition, adjuvant nivolumab improved disease-free survival (22...
QA:c4f88fdc0b7b9876a7ec671e
QAG:b812a8b0c0f7e86009e0038b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "7%) in advanced ESCC was higher than that of cohort B (47.9%) (P=0.019)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span referenc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8ffb7935cf6b3147dd217875","quotes":["The DCR of cohort A (71.7%) in advanced ESCC was higher than that of cohort ...
[ "CLM:8ffb7935cf6b3147dd217875", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9428701" ]
[ "SPAN:749f028f23a7eac4fa430df4" ]
[]
[]
{"qa_id":"QA:c4f88fdc0b7b9876a7ec671e","qa_group_id":"QAG:b812a8b0c0f7e86009e0038b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"7%) in advanced ESCC was higher than that of cohort B (47.9%) (P=0...
QA:c5ea6004ac005fd147ecfd2a
QAG:84511ab9862e8a30a097707f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Overexpression of CD73 promotes the malignant properties of cancers, such as proliferation, invasion, migration, adhesion, and metastasis, and it was associated with specific clinical characteristics and worse prognosis in many types of human cancers, including melanom...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:75a6b1c4de8ba26fc050e167","quotes":["Overexpression of CD73 promotes the malignant properties of cancers, such as...
[ "CLM:75a6b1c4de8ba26fc050e167", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:1b7b3fba0d4b71eec2d3373d" ]
[]
[]
{"qa_id":"QA:c5ea6004ac005fd147ecfd2a","qa_group_id":"QAG:84511ab9862e8a30a097707f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Overexpression of CD73 promotes the malignant properties of cancer...
QA:c6cc1522619ba38a618c4743
QAG:1796f85a55830246e7129528
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Compared with chemotherapy alone, our pooled analysis showed that the incidence rates of adverse effects were not significantly increased in ESCC patients who received chemo-immunotherapy, suggesting chemo-immunotherapy was a kind of treatment with high efficacy and sa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:76e8a16af42dadb52dd2bcfd","quotes":["Compared with chemotherapy alone, our pooled analysis showed that the incide...
[ "CLM:76e8a16af42dadb52dd2bcfd", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:b7732c3db7dcef78052cd131" ]
[]
[]
{"qa_id":"QA:c6cc1522619ba38a618c4743","qa_group_id":"QAG:1796f85a55830246e7129528","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Compared with chemotherapy alone, our pooled analysis showed that ...
QA:cb559601d9d00f98c5da8dcc
QAG:7e09260adb103b3b06e5a348
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Background In view of the fact that peripheral blood parameters have been reported as predictors of immunotherapy to various cancers, this study aims to evaluate the predictors of response to anti-programmed death-1 (anti-PD-1) therapy in patients with esophageal squam...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:31e848ae4221bd6fe6d69b90","quotes":["Background In view of the fact that peripheral blood parameters have been re...
[ "CLM:31e848ae4221bd6fe6d69b90", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8262036" ]
[ "SPAN:db93ed8cdeb25d81c28d514f" ]
[]
[]
{"qa_id":"QA:cb559601d9d00f98c5da8dcc","qa_group_id":"QAG:7e09260adb103b3b06e5a348","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Background In view of the fact that peripheral blood parameters ha...
QA:cdee4ff3ee4ca21340a57fb0
QAG:f8b01aa8a02cc85c9a124ab6
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Patients with resectable LA-ESCC who received nICT followed by surgery from Jun 2019 to Dec 2021 were identified in the database of our department"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3f38aee9db16d218c660a1b8","quotes":["Patients with resectable LA-ESCC who received nICT followed by surgery from ...
[ "CLM:3f38aee9db16d218c660a1b8", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:3b2825a94e4cff8a9b1a92de" ]
[]
[]
{"qa_id":"QA:cdee4ff3ee4ca21340a57fb0","qa_group_id":"QAG:f8b01aa8a02cc85c9a124ab6","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Patients with resectable LA-ESCC who received nICT followed by sur...
QA:cecaf5c8bf92ccbc3778ca58
QAG:040ebe80ba036806bba7f096
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Although immunotherapy alone did not improve PFS, the superior OS suggested that immunotherapy was also a good option for patients with ESCC who were refractory or intolerant to chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references....
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:67fed3a1e4ff970b39ad5a74","quotes":["Although immunotherapy alone did not improve PFS, the superior OS suggested ...
[ "CLM:67fed3a1e4ff970b39ad5a74", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC10185849" ]
[ "SPAN:fea593236473e275184604ac" ]
[]
[]
{"qa_id":"QA:cecaf5c8bf92ccbc3778ca58","qa_group_id":"QAG:040ebe80ba036806bba7f096","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Although immunotherapy alone did not improve PFS, the superior OS ...
QA:d1307a1d641d6d72f17d0792
QAG:9758a76851b42d1d456f361f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Co-culturing of PBMCs with an anticancer drug-treated esophageal squamous cell carcinoma cell line increased the CD20 and CD23 expression in PBMCs in vitro (Fig. 6 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance r...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:895d066fa589bfffc6a1abc1","quotes":["Co-culturing of PBMCs with an anticancer drug-treated esophageal squamous ce...
[ "CLM:895d066fa589bfffc6a1abc1", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9233387" ]
[ "SPAN:5e8d6b7ede1cc0b2c8510b1a" ]
[]
[]
{"qa_id":"QA:d1307a1d641d6d72f17d0792","qa_group_id":"QAG:9758a76851b42d1d456f361f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Co-culturing of PBMCs with an anticancer drug-treated esophageal s...
QA:d1d0e8ac26b9d8512b428586
QAG:c758c5c4abaf1c637bbda054
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "A total of 64 patients with advance inoperable ESCC receiving 200 mg every 3 weeks of Sintilimab plus Docetaxel (60 mg/m 2 ) and Carboplatin (AUC = 5) at two centers between January 2019 and June 2020 were included in this study approved by the two institutional review...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:02001ad96144c794bcc3e9a5","quotes":["A total of 64 patients with advance inoperable ESCC...
[ "CLM:02001ad96144c794bcc3e9a5", "CLM:08a48a247c9286d56048a968", "CLM:ba4f6489aaeb1263201db7e0", "CLM:11a8bd68e85fd714329111fe", "CLM:920eeff9e0fea211b0935088" ]
[ "PMCID:PMC8557514", "PMCID:PMC9606329", "PMCID:PMC8262036" ]
[ "SPAN:d248e03a9c0effcd8331ba03", "SPAN:d8fb2eb9246a7d330a888edb", "SPAN:72099f17d508c1f9bf2adb05", "SPAN:91fcf26088ed4609657329a5" ]
[ "ASC2:d6a1d7a195e23269d8bec94c", "ASC2:b0e5062d16e7b6fc01dbc769" ]
[ "HYP:DCH:bd6169127d9bf71668e2277d" ]
{"qa_id":"QA:d1d0e8ac26b9d8512b428586","qa_group_id":"QAG:c758c5c4abaf1c637bbda054","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"A total of 64 patients with advance inoperable ESCC receiving 200 ...
QA:d241a16b9ca0457c9db1f929
QAG:69f16a63e3458daa3d827ef4
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Similarly, for validation, the ‘IFN/EMT score’ was further shown to be associated with clinical benefits in a variety of advanced disease types (for example, metastatic urothelial cancer, melanoma, gastric cancer and nonsmall cell lung cancer) in patients who received ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8d51e75824136c5b52f08ec8","quotes":["Similarly, for validation, the ‘IFN/EMT score’ was further shown to be assoc...
[ "CLM:8d51e75824136c5b52f08ec8", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC10427424" ]
[ "SPAN:5edf79a545dfd64efb655eef" ]
[]
[]
{"qa_id":"QA:d241a16b9ca0457c9db1f929","qa_group_id":"QAG:69f16a63e3458daa3d827ef4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Similarly, for validation, the ‘IFN/EMT score’ was further shown t...
QA:d262a0cae265295172358a52
QAG:20c179c2be4404ff2c73a803
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Table 4 Characteristics of 38 ESCC patients who received pembrolizumab/nivolumab as second-line or later treatment"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage wi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8a5552ecce204ea2c512fcc7","quotes":["Table 4 Characteristics of 38 ESCC patients who received pembrolizumab/nivol...
[ "CLM:8a5552ecce204ea2c512fcc7", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:910e800fd9ba00ed46ce3972" ]
[]
[]
{"qa_id":"QA:d262a0cae265295172358a52","qa_group_id":"QAG:20c179c2be4404ff2c73a803","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Table 4 Characteristics of 38 ESCC patients who received pembroliz...
QA:d28461783a9ae5ed2b4f051b
QAG:0b49ed3b1e6eddd378f50c5f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In addition, KEYNOTE‐590 trial presented the incidence of the TRAEs and TRM for EAC and ESCC, which were included in the meta‐analysis considering that adverse events were mostly multiorgan systemic"? Return the original wording with paper, Claim, and Evidence Span ref...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:fcf7b244357569db61b96223","quotes":["In addition, KEYNOTE‐590 trial presented the incidence of the TRAEs and TRM ...
[ "CLM:fcf7b244357569db61b96223", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10363809" ]
[ "SPAN:5b949223ce46ecc281511a79" ]
[]
[]
{"qa_id":"QA:d28461783a9ae5ed2b4f051b","qa_group_id":"QAG:0b49ed3b1e6eddd378f50c5f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In addition, KEYNOTE‐590 trial presented the incidence of the TRAE...
QA:d3b7d1bcc69b5004dc3ab9d8
QAG:9cad9e6ab5ba5bf3fdb00aa2
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Patients and methods Three hundred and forty Asian patients with advanced/metastatic ESCC were enrolled in KEYNOTE-181, including the China cohort"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:59a2633333886af10f76673c","quotes":["Patients and methods Three hundred and forty Asian patients with advanced/me...
[ "CLM:59a2633333886af10f76673c", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8764510" ]
[ "SPAN:b87ae35c27747430318ac337" ]
[]
[]
{"qa_id":"QA:d3b7d1bcc69b5004dc3ab9d8","qa_group_id":"QAG:9cad9e6ab5ba5bf3fdb00aa2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Patients and methods Three hundred and forty Asian patients with a...
QA:d4a98dc6ae44ce542ce6a887
QAG:f97c8b43e11311438bc0ce59
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Pretreatment IINS was an independent predictor for pCR in LA-ESCC patients who received nICT"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and E...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:cfe060b18ee449c8e294ac68","quotes":["Pretreatment IINS was an independent predictor for pCR in LA-ESCC patients w...
[ "CLM:cfe060b18ee449c8e294ac68", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:bf58dbdc4bc95df087802cbf" ]
[]
[]
{"qa_id":"QA:d4a98dc6ae44ce542ce6a887","qa_group_id":"QAG:f97c8b43e11311438bc0ce59","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Pretreatment IINS was an independent predictor for pCR in LA-ESCC ...
QA:d4df24148ef66834cddff3b4
QAG:88629aa425e48402eff1d2a7
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "From July 2019 to March 2021, 47 patients with esophageal squamous cell carcinoma were enrolled in Jiangsu Tumor Hospital affiliated with Nanjing Medical University, and 45 patients underwent surgery ( Figure 1 )"? Return the original wording with paper, Claim, and Evi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:df21256bc8d0c316ba325ee1","quotes":["From July 2019 to March 2021, 47 patients with esophageal squamous cell carc...
[ "CLM:df21256bc8d0c316ba325ee1", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9606329" ]
[ "SPAN:ee4a0cde2bfb0a72aca88aa0" ]
[]
[]
{"qa_id":"QA:d4df24148ef66834cddff3b4","qa_group_id":"QAG:88629aa425e48402eff1d2a7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"From July 2019 to March 2021, 47 patients with esophageal squamous...
QA:d57ef0d7315f51aa3eeaa795
QAG:5ed02848a5bb0b01e6ecdbb0
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Figure 3 Pooled OS rates (A) and PFS rates (B) for the ICIs+TP and ICIs+FP groups among ESCC patients who received chemo-immunotherapy"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact s...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bc44c9b0b918898f03e21725","quotes":["Figure 3 Pooled OS rates (A) and PFS rates (B) for the ICIs+TP and ICIs+FP g...
[ "CLM:bc44c9b0b918898f03e21725", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:f4b26792fc67d2fcd69f5ea6" ]
[]
[]
{"qa_id":"QA:d57ef0d7315f51aa3eeaa795","qa_group_id":"QAG:5ed02848a5bb0b01e6ecdbb0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Figure 3 Pooled OS rates (A) and PFS rates (B) for the ICIs+TP and...
QA:d5a34a9b34eff829cf120df1
QAG:af689b35c37604ad2ada9443
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In the present study, we initially constructed and verified a novel score of IINS based on various pretreatment inflammatory and nutritional indexes to predict pCR in patients with LA-ESCC who received nICT"? Return the original wording with paper, Claim, and Evidence ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:271ef2ae6ac25da19ecda350","quotes":["In the present study, we initially constructed and verified a novel score of...
[ "CLM:271ef2ae6ac25da19ecda350", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:02842174876e5fe67b2375be" ]
[]
[]
{"qa_id":"QA:d5a34a9b34eff829cf120df1","qa_group_id":"QAG:af689b35c37604ad2ada9443","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In the present study, we initially constructed and verified a nove...
QA:d5c15e3e60f5b6e1af86ba70
QAG:84acdf56e1ef4528f14111dd
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "however, there were no statistical differences of PFS and OS between patients with CPS < 10 who received immunotherapy plus chemotherapy and chemotherapy alone"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance require...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:bc206482682b21b126599c24","quotes":["Another phase III study that focused on ESCC, KEYNOTE-590, showed that ESCC ...
[ "CLM:bc206482682b21b126599c24", "CLM:0313c682e9e59efb742366b7" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:e2e43868d1702bd797c7ec18" ]
[]
[]
{"qa_id":"QA:d5c15e3e60f5b6e1af86ba70","qa_group_id":"QAG:84acdf56e1ef4528f14111dd","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"however, there were no statistical differences of PFS and OS betwe...
QA:d6ecd766be1115339462f6d2
QAG:76e8604216b9635d12cf427e
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "scRNA-seq analysis demonstrated that TREM2 + TAMs was associated with immunosuppressive TME in ESCC and immunotherapy modulation"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact support...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f3c65ed6f298e4cc07f7ca9f","quotes":["3.5. scRNA-seq analysis demonstrated that TREM2 + TAMs were associated with ...
[ "CLM:f3c65ed6f298e4cc07f7ca9f", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10175681" ]
[ "SPAN:886e1551f6cf9a85dd59d05c" ]
[]
[]
{"qa_id":"QA:d6ecd766be1115339462f6d2","qa_group_id":"QAG:76e8604216b9635d12cf427e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"scRNA-seq analysis demonstrated that TREM2 + TAMs was associated w...
QA:d75fc3a1f8d6dcc6c5accb94
QAG:7e72ad61c7222bd94fe1a090
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In the context of adjuvant therapy for resectable ESCC, the randomized, double-blind, placebo-controlled phase III CheckMate 577 study demonstrated that 1-year adjuvant Nivolumab prolonged disease-free survival (DFS) (22.4m vs 11.0 m) and OS (29.7m vs 11.0m) in postope...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0f87746737e3f4978976c066","quotes":["3.1.2. In the context of adjuvant therapy for resectable ESCC, the randomize...
[ "CLM:0f87746737e3f4978976c066", "CLM:0991831bbf7006fe9faffdbf" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:cd067fe1f29a96785ca322fd" ]
[]
[]
{"qa_id":"QA:d75fc3a1f8d6dcc6c5accb94","qa_group_id":"QAG:7e72ad61c7222bd94fe1a090","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In the context of adjuvant therapy for resectable ESCC, the random...
QA:d7835f72de29e246f4f500dd
QAG:0cd9651c2a3072cd004c0d73
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "These changes have led to prolonged survival for ESCC patients, but questions remain which are challenging to answer in the context of single trial datasets"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requiremen...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f662a3e162951dc2e9f8efb5","quotes":["These changes have led to prolonged survival for ESCC patients, but question...
[ "CLM:f662a3e162951dc2e9f8efb5", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8804258" ]
[ "SPAN:cd9d323d7f56ea39ad2ef6f2" ]
[]
[]
{"qa_id":"QA:d7835f72de29e246f4f500dd","qa_group_id":"QAG:0cd9651c2a3072cd004c0d73","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"These changes have led to prolonged survival for ESCC patients, bu...
QA:d7e3b20639a20465147fae09
QAG:556e686a1aae83cf4da75339
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Inclusion criteria were included patients with locally advanced resectable stage ESCC; the disease was histopathologically confirmed in tissue samples; receiving simple nCT or plus ICIs following esophagectomy; at least one of the following primary outcomes were report...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:3854cbb573dcd1d4a85c0b97","quotes":["Inclusion criteria were included: patients with locally advanced resectable ...
[ "CLM:3854cbb573dcd1d4a85c0b97", "CLM:4df10b4f9a49b50b91130530" ]
[ "PMCID:PMC9585292" ]
[ "SPAN:80db3f8a184bb3e9ed8b0f3b" ]
[]
[]
{"qa_id":"QA:d7e3b20639a20465147fae09","qa_group_id":"QAG:556e686a1aae83cf4da75339","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Inclusion criteria were included patients with locally advanced re...
QA:d8112901f600ef30dc4488f4
QAG:2c63498fe58959d3a42e9c10
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In our meta-analysis, second-line PD-1 blockade decreased the risk of death by 27% in patients with advanced ESCC when comparing conventional chemotherapy (HR = 0.73, P < 0.001)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:315ada46466f55c23a6eebfd","quotes":["In our meta-analysis, second-line PD-1 blockade decreased the risk of death ...
[ "CLM:315ada46466f55c23a6eebfd", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8579527" ]
[ "SPAN:cb3eb11dcc5be174e3240ed1" ]
[]
[]
{"qa_id":"QA:d8112901f600ef30dc4488f4","qa_group_id":"QAG:2c63498fe58959d3a42e9c10","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In our meta-analysis, second-line PD-1 blockade decreased the risk...
QA:db124aa3bbcd46a49c340236
QAG:b9cea559e24ae223dd968f54
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "We further validated the predictive power of molecular subtypes in an independent cohort of 36 Chinese ESCC patients who had received PD-1/PD-L1 therapy in combination with chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references. Int...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:4fbb69ca29a1a59e5e60050a","quotes":["We further validated the predictive power of molecular subtypes in an indepe...
[ "CLM:4fbb69ca29a1a59e5e60050a", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9599230" ]
[ "SPAN:e9cedaf3a496db11093c6bcd" ]
[]
[]
{"qa_id":"QA:db124aa3bbcd46a49c340236","qa_group_id":"QAG:b9cea559e24ae223dd968f54","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"We further validated the predictive power of molecular subtypes in...
QA:db165e142a50c607acb50acd
QAG:1bf02e6d8344642da9b025d0
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "3% of the ESCC patients who received chemo-immunotherapy discontinued treatment because of adverse effects ( 11 – 14 )"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passag...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a888157ae40be5a3a88bd51","quotes":["It has been reported that 11.7%-45.3% of the ESCC patients who received chem...
[ "CLM:9a888157ae40be5a3a88bd51", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:430fa75d2a9bb16e0d5c2a28" ]
[]
[]
{"qa_id":"QA:db165e142a50c607acb50acd","qa_group_id":"QAG:1bf02e6d8344642da9b025d0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"3% of the ESCC patients who received chemo-immunotherapy discontin...
QA:dc201405ecdba5fc79f0496f
QAG:6502e671077f2b60f340fae4
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "A total of 10 articles (1688 ESCC patients) were included in the final analysis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9a1e8a74c28d7fc91ec33476","quotes":["A total of 10 articles (1688 ESCC patients) were included in the final analy...
[ "CLM:9a1e8a74c28d7fc91ec33476", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:cab40c5448d93b025e65cb24" ]
[]
[]
{"qa_id":"QA:dc201405ecdba5fc79f0496f","qa_group_id":"QAG:6502e671077f2b60f340fae4","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"A total of 10 articles (1688 ESCC patients) were included in the f...
QA:dd7ad13a56fc2fda239fc839
QAG:a7f097c876c56340661c7940
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Moreover, the transwell assay revealed knockdown of CD73 in two ESCC cell lines, TE1 and KYSE30, exhibited decreased abilities of cell invasion and migration"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requireme...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:df99c56962afa62839f23cc7","quotes":["In addition, we selected another cohort consisting of 38 ESCC patients recei...
[ "CLM:df99c56962afa62839f23cc7", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:e31de79de3077022a039066c" ]
[]
[]
{"qa_id":"QA:dd7ad13a56fc2fda239fc839","qa_group_id":"QAG:a7f097c876c56340661c7940","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Moreover, the transwell assay revealed knockdown of CD73 in two ES...
QA:e04f892fd5928390f4f0cc7b
QAG:661b6d6f8d1a81b2e285c1a1
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "showed that PD‐1/PD‐L1based immune checkpoint inhibitors decreased CPS ≥10 ESCC patients compared with chemotherapy"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage w...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:50b625ebc480e5f41fca81c1","quotes":["22 , 23 , 24 , 25 A meta‐analysis by Leone et al. showed that PD‐1/PD‐L1base...
[ "CLM:50b625ebc480e5f41fca81c1", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10363809" ]
[ "SPAN:e9c661602207533cf65fed7a" ]
[]
[]
{"qa_id":"QA:e04f892fd5928390f4f0cc7b","qa_group_id":"QAG:661b6d6f8d1a81b2e285c1a1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"showed that PD‐1/PD‐L1based immune checkpoint inhibitors decreased...
QA:e2ab29aabcfab9a7ed79c643
QAG:5bae133953b31219c2bf21eb
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Immunotherapy, with agents such as immune checkpoint inhibitors (ICIs), cancer vaccines, and adoptive T-cell therapy, has recently increased hope for improved survival outcomes in patients with esophageal cancer ( 4 – 7 )"? Return the original wording with paper, Claim...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:abb01e3e354a91216ac59698","quotes":["Immunotherapy, with agents such as immune checkpoint inhibitors (ICIs), canc...
[ "CLM:abb01e3e354a91216ac59698", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC8724211" ]
[ "SPAN:37f14215d0176fb3050d553e" ]
[]
[]
{"qa_id":"QA:e2ab29aabcfab9a7ed79c643","qa_group_id":"QAG:5bae133953b31219c2bf21eb","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Immunotherapy, with agents such as immune checkpoint inhibitors (I...
QA:e3330787d8c18f24e6480cd2
QAG:2890c9263cf6815e0390333b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Table 3 Pooled incidence rates of adverse events in ESCC patients who received chemo-immunotherapy"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim,...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:79257d14845eb88760d4ab03","quotes":["Table 3 Pooled incidence rates of adverse events in ESCC patients who receiv...
[ "CLM:79257d14845eb88760d4ab03", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:a14eca4cb564ec7326571d0e" ]
[]
[]
{"qa_id":"QA:e3330787d8c18f24e6480cd2","qa_group_id":"QAG:2890c9263cf6815e0390333b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Table 3 Pooled incidence rates of adverse events in ESCC patients ...
QA:e42fa03ffae8a55e1900ca4d
QAG:e677088fbd6d3544fcedd731
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Background Immunotherapy has largely improved clinical outcome of patients with esophageal squamous cell carcinoma (ESCC)"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting pas...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8ce5e2e9da6cba1a7de8b2f9","quotes":["Background Immunotherapy has largely improved clinical outcome of patients w...
[ "CLM:8ce5e2e9da6cba1a7de8b2f9", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10992089" ]
[ "SPAN:87310442dfc77164c8c3673d" ]
[]
[]
{"qa_id":"QA:e42fa03ffae8a55e1900ca4d","qa_group_id":"QAG:e677088fbd6d3544fcedd731","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Background Immunotherapy has largely improved clinical outcome of ...
QA:e458fa96782f1e52927d82a5
QAG:048d30792082256f5ee81a4b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "For resectable or potentially resectable locally advanced ESCC, the current treatment paradigm established by the CROSS study and the NEOCRTEC5010 study is neoadjuvant chemoradiotherapy followed by surgery, which has achieved a pathologic complete response (pCR) rate o...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:7b09ceed1a23b60e1fa2444c","quotes":["For resectable or potentially resectable locally advanced ESCC, the current ...
[ "CLM:7b09ceed1a23b60e1fa2444c", "CLM:2a0dc33e26036765ea69bb10" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:534cee3df5e2cc61c9ca4b20" ]
[]
[]
{"qa_id":"QA:e458fa96782f1e52927d82a5","qa_group_id":"QAG:048d30792082256f5ee81a4b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"For resectable or potentially resectable locally advanced ESCC, th...
QA:e8ad120f0264aae87121d86d
QAG:60e55878e025f8abd5b3dbba
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Results A total of 66 patients with locally advanced ESCC were included in this study, including 8 patients with stage II, 29 patients with stage III, and 29 patients with stage IVA"? Return the original wording with paper, Claim, and Evidence Span references. Integra...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:5e27c3809de7ce5c43215d53","quotes":["Results A total of 66 patients with locally advanced ESCC were included in t...
[ "CLM:5e27c3809de7ce5c43215d53", "CLM:23c554d40e73d21b46b8fb97" ]
[ "PMCID:PMC9577786" ]
[ "SPAN:e2e42ce38b73792731af90c9" ]
[]
[]
{"qa_id":"QA:e8ad120f0264aae87121d86d","qa_group_id":"QAG:60e55878e025f8abd5b3dbba","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Results A total of 66 patients with locally advanced ESCC were inc...
QA:e8d5e4e5e0cc4596fd5c4939
QAG:68dc562d1ca248464ec9b2d3
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In the CheckMate 648 study, the PD-L1 status was associated with the efficacy of ICIs in ESCC patients"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Cl...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9d4b88929eb1003dff2d66ba","quotes":["In the CheckMate 648 study, the PD-L1 status was associated with the efficac...
[ "CLM:9d4b88929eb1003dff2d66ba", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9599230" ]
[ "SPAN:ece1001dc22c50ea3e3d937b" ]
[]
[]
{"qa_id":"QA:e8d5e4e5e0cc4596fd5c4939","qa_group_id":"QAG:68dc562d1ca248464ec9b2d3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In the CheckMate 648 study, the PD-L1 status was associated with t...
QA:ed5a4742553c55d5589c1400
QAG:2e051f6358475d498faea47f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "A nomogram was established to predict pCR according to the independent predictors (cTNM and IINS) identified in the multivariate logistic regression analyses for patients with LA-ESCC who received nICT ( Figure 7A )"? Return the original wording with paper, Claim, and ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:aa4f5863b881fca29d410abc","quotes":["A nomogram was established to predict pCR according to the independent predi...
[ "CLM:aa4f5863b881fca29d410abc", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:06851112729b766997406b43" ]
[]
[]
{"qa_id":"QA:ed5a4742553c55d5589c1400","qa_group_id":"QAG:2e051f6358475d498faea47f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"A nomogram was established to predict pCR according to the indepen...
QA:eef10e64f3ac6d66c264fd67
QAG:681cf341eb8837f66612278f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "This is a retrospective study to assess neoadjuvant camrelizumab plus chemotherapy for locally advanced ESCC patients, which achieved a promising MPR rate of 50.0%, a pCR rate of 35.3%, and the R0 resection rate of 94.1%"? Return the original wording with paper, Claim,...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ad11e09b8514e3713f2b5f28","quotes":["This is a retrospective study to assess neoadjuvant camrelizumab plus chemot...
[ "CLM:ad11e09b8514e3713f2b5f28", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9251418" ]
[ "SPAN:6f064298fc738f222e1de75b" ]
[]
[]
{"qa_id":"QA:eef10e64f3ac6d66c264fd67","qa_group_id":"QAG:681cf341eb8837f66612278f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"This is a retrospective study to assess neoadjuvant camrelizumab p...
QA:f1308daab6b83df9359751f4
QAG:f8130448a1244da2b40bfe97
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "We also enrolled patients with ESCC who received ICBs (including pembrolizumab and nivolumab) as second-line and later-line treatment in our institute between July 2020 and June 2021. Thirty-eight patients with ESCC were present in this cohort"? Return the original wor...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6e88d02645ad4ab7ec6931fc","quotes":["We also enrolled patients with ESCC who received ICBs (including pembrolizum...
[ "CLM:6e88d02645ad4ab7ec6931fc", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:4e3867f603cf3483249e1151" ]
[]
[]
{"qa_id":"QA:f1308daab6b83df9359751f4","qa_group_id":"QAG:f8130448a1244da2b40bfe97","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"We also enrolled patients with ESCC who received ICBs (including p...
QA:f2ece38053cbdb4018033353
QAG:b7e65a2e807c38648d1ae36e
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "compared surgery after chemoradiotherapy to surgery alone in patients with esophageal cancer and found that preoperative chemoradiotherapy improved the survival of patients with potentially resectable esophageal cancer ( 10 )"? Return the original wording with paper, C...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:08a48a247c9286d56048a968","quotes":["And adjuvant treatment has been demonstrated to reduce the postoperative rec...
[ "CLM:08a48a247c9286d56048a968", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9577786" ]
[ "SPAN:d113d4905922f398548c1a8c" ]
[]
[]
{"qa_id":"QA:f2ece38053cbdb4018033353","qa_group_id":"QAG:b7e65a2e807c38648d1ae36e","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"compared surgery after chemoradiotherapy to surgery alone in patie...
QA:f3f8d006b6dd566ded37064e
QAG:39a0c8cab8576e34ad5a6fed
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "[ 26b ] Here, we found that ATRA inhibited ESCC tumor initiation and progression by promoting OTUD6B translation and inhibiting TIC properties of ESCC cancer cells"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance req...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:cfc1021db89b304b25a0e3da","quotes":["ATRA has been reported for its function in treating acute promyelocytic leuk...
[ "CLM:cfc1021db89b304b25a0e3da", "CLM:0991831bbf7006fe9faffdbf" ]
[ "PMCID:PMC10238178" ]
[ "SPAN:da9d3fb412f12a123678ef34" ]
[]
[]
{"qa_id":"QA:f3f8d006b6dd566ded37064e","qa_group_id":"QAG:39a0c8cab8576e34ad5a6fed","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"[ 26b ] Here, we found that ATRA inhibited ESCC tumor initiation a...
QA:f412b50c333400b180f1b676
QAG:36245e3fa05297703b5b2982
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Recently, the use of immunotherapy in esophageal cancer has been increasingly promoted from second-line to first-line treatment"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporti...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:f7c9d5bf1ccdd05e69aae4d9","quotes":["Recently, the use of immunotherapy in esophageal cancer has been increasingl...
[ "CLM:f7c9d5bf1ccdd05e69aae4d9", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC10714592" ]
[ "SPAN:185e4803f79e433ce003af79" ]
[]
[]
{"qa_id":"QA:f412b50c333400b180f1b676","qa_group_id":"QAG:36245e3fa05297703b5b2982","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Recently, the use of immunotherapy in esophageal cancer has been i...
QA:f4927ce2ccb74818beb03df0
QAG:31e14fdc19a8e7a359a79b7f
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Moreover, only OTUD6B but no other OTU family members was able to regulate β ‐TrCP, since knock down OTUD6A or OTUD2 did not improve β ‐TrCP protein level in ESCC cells (Figure S1E–H , Supporting Information)"? Return the original wording with paper, Claim, and Evidenc...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9c73cda88824e22c589117e1","quotes":["Moreover, only OTUD6B but no other OTU family members was able to regulate β...
[ "CLM:9c73cda88824e22c589117e1", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10238178" ]
[ "SPAN:c2e7de2ee6c132cc4aadf16f" ]
[]
[]
{"qa_id":"QA:f4927ce2ccb74818beb03df0","qa_group_id":"QAG:31e14fdc19a8e7a359a79b7f","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Moreover, only OTUD6B but no other OTU family members was able to ...
QA:f591abc155d968e58a88d106
QAG:3f5e26367c343c69faa0a333
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In a phase III study of advanced esophageal cancer, KEYNOTE-181, patients with CPS ≥ 10 who received pembrolizumab had a better response rate and OS compared to those who received chemotherapy"? Return the original wording with paper, Claim, and Evidence Span reference...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:425974891808dce8b8d00e8e","quotes":["In a phase III study of advanced esophageal cancer, KEYNOTE-181, patients wi...
[ "CLM:425974891808dce8b8d00e8e", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC8393769" ]
[ "SPAN:a3b22a554f92238d551cc368" ]
[]
[]
{"qa_id":"QA:f591abc155d968e58a88d106","qa_group_id":"QAG:3f5e26367c343c69faa0a333","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In a phase III study of advanced esophageal cancer, KEYNOTE-181, p...
QA:f59c456afdf0e3c5da86dd7f
QAG:bd049f0889f650078c8f3fe7
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "The meta‐analysis showed that immunochemotherapy decreased the overall risk of death by 32% and the risk of disease progression or death by 38% in advanced ESCC patients compared with chemotherapy (OS: HR = 0.68, 95% CI 0.61–0.75; PFS: HR = 0.62, 95% CI 0.55–0.70, resp...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:566e53b2b4c06981d3943b35","quotes":["The meta‐analysis showed that immunochemotherapy reduced the overall risk of...
[ "CLM:566e53b2b4c06981d3943b35", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10363809" ]
[ "SPAN:d9c2e90b6fe3e55400194bf4" ]
[]
[]
{"qa_id":"QA:f59c456afdf0e3c5da86dd7f","qa_group_id":"QAG:bd049f0889f650078c8f3fe7","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"The meta‐analysis showed that immunochemotherapy decreased the ove...
QA:f5afb33679bc5d5bcd21e0ad
QAG:ef6ede0cb602a4bf26d79581
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "These results suggested that ICI as second- or later-line treatment for patients with locally advanced or metastatic ESCC was associated with an increased risk of response compared with chemotherapy"? Return the original wording with paper, Claim, and Evidence Span ref...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:8cbc0ff5726c04a7d21e1cfe","quotes":["These results suggested that ICI as second- or later-line treatment for pati...
[ "CLM:8cbc0ff5726c04a7d21e1cfe", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8724211" ]
[ "SPAN:a89f9a49224c567aa446bee1" ]
[]
[]
{"qa_id":"QA:f5afb33679bc5d5bcd21e0ad","qa_group_id":"QAG:ef6ede0cb602a4bf26d79581","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"These results suggested that ICI as second- or later-line treatmen...
QA:f76b638b21f6ce812bf50399
QAG:ec3fcdea557b15f8369473fa
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "According to the inclusion and exclusion criteria, 453 patients diagnosed with locally advanced ESCC from March 2013 to April 2021 were enrolled of whom 48 patients were in the nCT+ICIs group, and 405 patients were in the nCT group"? Return the original wording with pa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0313c682e9e59efb742366b7","quotes":["According to the inclusion and exclusion criteria, 453 patients diagnosed wi...
[ "CLM:0313c682e9e59efb742366b7", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9585292" ]
[ "SPAN:7046e2bb6a629a502ff3f12c" ]
[]
[]
{"qa_id":"QA:f76b638b21f6ce812bf50399","qa_group_id":"QAG:ec3fcdea557b15f8369473fa","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"According to the inclusion and exclusion criteria, 453 patients di...
QA:f77216347a2aacf3cd510512
QAG:284458783202d346947d6f82
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "2%) patients achieved pCR, the MPR rate was 62.5%, the clinical downstaging rate was 83.3%, pathological downstaging was achieved in 74.0% of patients, and 1-year DFS rate was 95.2%"? Return the original wording with paper, Claim, and Evidence Span references. Integra...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:76287602e1565b9f4401c7cf","quotes":["In the present study, neoadjuvant sintilimab plus chemotherapy in patients w...
[ "CLM:76287602e1565b9f4401c7cf", "CLM:2a0dc33e26036765ea69bb10" ]
[ "PMCID:PMC9098952" ]
[ "SPAN:2e842f6306c6c5e676c93097" ]
[]
[]
{"qa_id":"QA:f77216347a2aacf3cd510512","qa_group_id":"QAG:284458783202d346947d6f82","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"2%) patients achieved pCR, the MPR rate was 62.5%, the clinical do...
QA:f7d5efd9c08e947282b4e703
QAG:f0ccbcfc0d84f2b7b7c568ab
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In this study, we aims to evaluate the potential predictive value of CT-derived radiomics in advanced ESCC patients receiving immune-checkpoint inhibitor plus chemotherapy (ICI + CT)"? Return the original wording with paper, Claim, and Evidence Span references. Integr...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:0ea450c7cc5fd215e0694270","quotes":["In this study, we aimed to evaluate the potential predictive value of CT-der...
[ "CLM:0ea450c7cc5fd215e0694270", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8557514" ]
[ "SPAN:826d84be50492b48d9ea0e8c" ]
[]
[]
{"qa_id":"QA:f7d5efd9c08e947282b4e703","qa_group_id":"QAG:f0ccbcfc0d84f2b7b7c568ab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In this study, we aims to evaluate the potential predictive value ...
QA:f7fd9f50e3838e850ed1af39
QAG:397998a5c64a2623d11649f3
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "trial participants in the PD-1 inhibitor arm received anti-PD-1 agent only, while participants in the chemotherapy arm were treated with conventional chemotherapy regimen; and the trial used at least three of the following (OS, progression-free survival [PFS], objectiv...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:6d8b372feb2f9490a744540e","quotes":["Studies eligible for the analyses satisfied each of the following requiremen...
[ "CLM:6d8b372feb2f9490a744540e", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8579527" ]
[ "SPAN:947e310371175820538cead3" ]
[]
[]
{"qa_id":"QA:f7fd9f50e3838e850ed1af39","qa_group_id":"QAG:397998a5c64a2623d11649f3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"trial participants in the PD-1 inhibitor arm received anti-PD-1 ag...
QA:f830698b5a601ac377772307
QAG:cef61794e1d1f4a9dff36fa1
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "We have previously reported that the presence of TLSs around gastric cancer was associated with a good prognosis, that increased granzyme B and perforin expression is observed around TLSs, and that memory T cells are present around TLSs"? Return the original wording wi...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d383437af8ee866436540c2f","quotes":["We have previously reported that the presence of TLSs around gastric cancer ...
[ "CLM:d383437af8ee866436540c2f", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9233387" ]
[ "SPAN:45a2a8f4c82bf35ae7a0103b" ]
[]
[]
{"qa_id":"QA:f830698b5a601ac377772307","qa_group_id":"QAG:cef61794e1d1f4a9dff36fa1","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"We have previously reported that the presence of TLSs around gastr...
QA:f83392ae0d6bc9acfc9558c3
QAG:23ff39f6789013225e5e7fda
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "in the ESCC subgroup, the OS was also improved at 12.6 months v"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; asse...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:a29735543216d0090761d54d","quotes":["In the KEYNOTE-590 trial, pembrolizumab plus chemotherapy exhibited a superi...
[ "CLM:a29735543216d0090761d54d", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10714592" ]
[ "SPAN:f885c3f515417d73270790e1" ]
[]
[]
{"qa_id":"QA:f83392ae0d6bc9acfc9558c3","qa_group_id":"QAG:23ff39f6789013225e5e7fda","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"in the ESCC subgroup, the OS was also improved at 12.6 months v\"?...
QA:f880a71c8fc5a700a0738de5
QAG:4420ba8f9fcc36caf9bb6d56
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "119 patients with ESCC who received anti-PD-1 inhibitor treatment from December 2018 to September 2020 in Sun Yat-sen University Cancer Center, Guangzhou were included in this retrospective study"? Return the original wording with paper, Claim, and Evidence Span refere...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:637e88f9f24574c1afdd4b4e","quotes":["119 patients with ESCC who received anti-PD-1 inhibitor treatment from Decem...
[ "CLM:637e88f9f24574c1afdd4b4e", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8262036" ]
[ "SPAN:203a3dccb0b93fde6413dc53" ]
[]
[]
{"qa_id":"QA:f880a71c8fc5a700a0738de5","qa_group_id":"QAG:4420ba8f9fcc36caf9bb6d56","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"119 patients with ESCC who received anti-PD-1 inhibitor treatment ...
QA:fa8ac4a24f2834b72bd9b0cb
QAG:a28af26044c0d6e8d0669b09
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Secondly, in this systematic review and meta-analysis, a total of 1651 ESCC patients from 9 studies received anti-PD1 therapy (tislelizumab, toripalimab, pembrolizumab, camrelizumab, sintilimab, and nivolumab) and only 37 patients from 1 study received anti-PD-L1 thera...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:ae37f8a84ac7e7a186fb1e35","quotes":["Secondly, in this systematic review and meta-analysis, a total of 1651 ESCC ...
[ "CLM:ae37f8a84ac7e7a186fb1e35", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC9808083" ]
[ "SPAN:0f3aaa826acab02f48654fa0" ]
[]
[]
{"qa_id":"QA:fa8ac4a24f2834b72bd9b0cb","qa_group_id":"QAG:a28af26044c0d6e8d0669b09","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Secondly, in this systematic review and meta-analysis, a total of ...
QA:fab2fbcd6cf7f8e477d67b5d
QAG:8f7c64c5c23d905c018417c8
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Higher doses of neoadjuvant radiation for esophageal cancer did not improve the pathologic complete response rate or survival: a propensity-matched analysis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requiremen...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:65ca74e0888d4dadb9030e62","quotes":["Higher doses of neoadjuvant radiation for esophageal cancer do not affect th...
[ "CLM:65ca74e0888d4dadb9030e62", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC10261849" ]
[ "SPAN:5d5956dc6aa67a57eecb06f8" ]
[]
[]
{"qa_id":"QA:fab2fbcd6cf7f8e477d67b5d","qa_group_id":"QAG:8f7c64c5c23d905c018417c8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Higher doses of neoadjuvant radiation for esophageal cancer did no...
QA:fbca68e14578b4a928a11de1
QAG:a90d76fb2c2c38d654fefcab
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "5%) patients achieved pCR"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact supporting passage with paper, Claim, and Evidence Span references; assess the embedded target Claim only agai...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:53f595b2e5be60ea885f52ca","quotes":["Results Of the 285 enrolled LA-ESCC patients received nICT followed by radic...
[ "CLM:53f595b2e5be60ea885f52ca", "CLM:02001ad96144c794bcc3e9a5" ]
[ "PMCID:PMC9271687" ]
[ "SPAN:538b7a39ad4c3d2be43400f4" ]
[]
[]
{"qa_id":"QA:fbca68e14578b4a928a11de1","qa_group_id":"QAG:a90d76fb2c2c38d654fefcab","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"5%) patients achieved pCR\"? Return the original wording with pape...
QA:fc8f26f5428d483e9654a0c9
QAG:71700b787e1c5fcf8a970161
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "In this study, we aims to evaluate the safety and effectiveness of camrelizumab combined with chemotherapy as a neoadjuvant regimen in the treatment of locally advanced ESCC"? Return the original wording with paper, Claim, and Evidence Span references. Integrated prov...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b37b5af0b3513e6f0e521ae1","quotes":["In this study, we aimed to investigate the safety and effectiveness of camre...
[ "CLM:b37b5af0b3513e6f0e521ae1", "CLM:271ef2ae6ac25da19ecda350" ]
[ "PMCID:PMC9577786" ]
[ "SPAN:b3a6861c582d4f657881973b" ]
[]
[]
{"qa_id":"QA:fc8f26f5428d483e9654a0c9","qa_group_id":"QAG:71700b787e1c5fcf8a970161","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"In this study, we aims to evaluate the safety and effectiveness of...
QA:ff74bf6d44a8b91ad43c2490
QAG:fe3d0ca3ed747fca61e896ed
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Results Eleven phase 3 randomized controlled trials (RCTs) involving 6267 patients with ESCC were included in this meta-analysis"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exact support...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:70c34f24958201ce03d2e417","quotes":["Results Eleven phase 3 randomized controlled trials (RCTs) involving 6267 pa...
[ "CLM:70c34f24958201ce03d2e417", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC10185849" ]
[ "SPAN:a1a1e85d7919d8bd72a12b9a" ]
[]
[]
{"qa_id":"QA:ff74bf6d44a8b91ad43c2490","qa_group_id":"QAG:fe3d0ca3ed747fca61e896ed","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Results Eleven phase 3 randomized controlled trials (RCTs) involvi...
QA:ffd0317305b6593968cb689c
QAG:273b885a303d1087f9834ea8
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "This retrospective study reviewed the electronic medical records of patients with esophageal cancer who received anlotinib plus PD-1 blockade or anlotinib monotherapy as second or further-line therapy from January 2019 to February 2021 at Henan Cancer Hospital"? Return...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:2a0dc33e26036765ea69bb10","quotes":["This retrospective study reviewed the electronic medical records of patients...
[ "CLM:2a0dc33e26036765ea69bb10", "CLM:0313c682e9e59efb742366b7" ]
[ "PMCID:PMC9428701" ]
[ "SPAN:e5eb219f30f6b11e84fc5430" ]
[]
[]
{"qa_id":"QA:ffd0317305b6593968cb689c","qa_group_id":"QAG:273b885a303d1087f9834ea8","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"This retrospective study reviewed the electronic medical records o...
QA:fff4341b1315a318e24ca524
QAG:1cdf0edae883f5fdc9216b7b
provenance_qa
exact_evidence_retrieval
provenance_qa
G023
en
train
Which exact source passage supports the statement "Meta-analysis of three RCTs comprising 1268 patients revealed that ICI treatment improved median OS compared with chemotherapy when used as second- or later-line treatment of locally advanced or metastatic ESCC"? Return the original wording with paper, Claim, and Evide...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:155fac513205cdf17803defe","quotes":["Meta-analysis of three RCTs comprising 1268 patients revealed that ICI treat...
[ "CLM:155fac513205cdf17803defe", "CLM:08a48a247c9286d56048a968" ]
[ "PMCID:PMC8724211" ]
[ "SPAN:65d761af5474c4cb7707caba" ]
[]
[]
{"qa_id":"QA:fff4341b1315a318e24ca524","qa_group_id":"QAG:1cdf0edae883f5fdc9216b7b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G023","question":"Which exact source passage supports the statement \"Meta-analysis of three RCTs comprising 1268 patients revealed that...
QA:02b06f0199d9335b11208da1
QAG:2710405ba7cb6bf6a6b517a0
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "Targeting VEGFR2 with ramucirumab increased PD-L1 expression and CD8+ T cell infiltration in the tumor microenvironment of patients with advanced gastric cancer and reduced the frequency of immunosuppressive effector regulatory T cells in tumor-infiltrating lymphocytes...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:878f99c401450b2636afba6b","quotes":["Targeting VEGFR2 with ramucirumab increased PD-L1 expression and CD8+ T cell...
[ "CLM:878f99c401450b2636afba6b", "CLM:072282e1a03a6f258ddcaf17" ]
[ "PMCID:PMC7602637" ]
[ "SPAN:b3216ec6699fe62239253b11" ]
[]
[]
{"qa_id":"QA:02b06f0199d9335b11208da1","qa_group_id":"QAG:2710405ba7cb6bf6a6b517a0","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"Targeting VEGFR2 with ramucirumab increased PD-L1 expression and C...
QA:02f1a17b55e30a924502eabf
QAG:4bd14e0f44ec4884e7639988
provenance_qa
paper_evidence_availability
provenance_qa
G024
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC10613141? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiabl...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC10613141","verdict":"no_released_traceable_claim","reason":"No...
[]
[ "PMCID:PMC10613141" ]
[]
[]
[]
{"qa_id":"QA:02f1a17b55e30a924502eabf","qa_group_id":"QAG:4bd14e0f44ec4884e7639988","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G024","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC1061314...
QA:0921404391af8d7da2cbab1f
QAG:0c6c7c4b733aa48107fbcab7
provenance_qa
paper_evidence_availability
provenance_qa
G024
en
train
Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9357620? Explicitly abstain if it does not. Integrated provenance requirements: report evidence availability or insufficiency without inventing missing full text. Keep each subtask answer separately identifiable...
{"answer_type":"integrated_provenance","embedded_answer_types":["paper_evidence_availability"],"exact_evidence_retrieval":null,"limited_evidence_retrieval":null,"paper_evidence_availability":{"answer_type":"explicit_evidence_abstention","paper_id":"PMCID:PMC9357620","verdict":"no_released_traceable_claim","reason":"No ...
[]
[ "PMCID:PMC9357620" ]
[]
[]
[]
{"qa_id":"QA:0921404391af8d7da2cbab1f","qa_group_id":"QAG:0c6c7c4b733aa48107fbcab7","qa_family":"provenance_qa","subtask_type":"paper_evidence_availability","language":"en","cluster_id":"G024","question":"Does the current traceable evidence dataset contain a usable Claim and exact source span for paper PMCID:PMC9357620...
QA:0dc4e52d7009359f257eb2f4
QAG:005e51b1d004b1bd959dabd3
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "suggested that treating esophageal or G/GEJ cancer with PD-1/PD-L1 inhibitors led to a higher pooled hazard ratio (HR) for overall survival (OS) and progression-free survival (PFS), indicating their ineffectiveness"? Return the original wording with paper, Claim, and E...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:072282e1a03a6f258ddcaf17","quotes":["A meta-analysis conducted by Wang et al. [ 8 ] sugg...
[ "CLM:072282e1a03a6f258ddcaf17", "CLM:03ccfa8216f57bebab8dab3a", "CLM:6ee7ab0c2b485e3cec13aff8" ]
[ "PMCID:PMC8397221", "PMCID:PMC7602637" ]
[ "SPAN:b090b5b651896cb19b6ff8b3", "SPAN:0ab3c196ce00c5481ec81caa" ]
[ "ASC2:3bd33acc30cde3d844aa36e3" ]
[ "HYP:DCH:bad022e9565efb8163a44707" ]
{"qa_id":"QA:0dc4e52d7009359f257eb2f4","qa_group_id":"QAG:005e51b1d004b1bd959dabd3","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"suggested that treating esophageal or G/GEJ cancer with PD-1/PD-L1...
QA:0f234b4a7d4194314c4dcc12
QAG:2a164a0fe31e86e021e1c15b
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "In a phase 2 study of G/GEJ cancer patients who received ≥ 2 lines of prior therapy, targeting the PD-1 receptor with pembrolizumab benefited a minority of patients, with approximately 80% of patients rapidly progressing, and a response rate of 15.5% in patients with P...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9285985a5af7933bbecaa2c4","quotes":["In a phase 2 study of G/GEJ cancer patients who received ≥ 2 lines of prior ...
[ "CLM:9285985a5af7933bbecaa2c4", "CLM:5de3f7118846b520e68dd9bf" ]
[ "PMCID:PMC7602637" ]
[ "SPAN:a52f0c6290747f879259dbb3" ]
[]
[]
{"qa_id":"QA:0f234b4a7d4194314c4dcc12","qa_group_id":"QAG:2a164a0fe31e86e021e1c15b","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"In a phase 2 study of G/GEJ cancer patients who received ≥ 2 lines...
QA:11032792c9626927ad5e57d3
QAG:50c3d603a1b6c465ca49fd16
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "In the present study, we conducted a 2-cohort phase 2 trial in which cohort 1 aims to evaluate the antitumor activity and safety of HX008 plus irinotecan as second-line treatment in patients with advance G/GEJ cancer"? Return the original wording with paper, Claim, and...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:c71b11d5fa482ce5b985c667","quotes":["In the present study, we conducted a 2-cohort phase 2 trial in which cohort ...
[ "CLM:c71b11d5fa482ce5b985c667", "CLM:32fd278c95b64d239d4e1a49" ]
[ "PMCID:PMC7566427" ]
[ "SPAN:d8523627d3c2647a94178f0c" ]
[]
[]
{"qa_id":"QA:11032792c9626927ad5e57d3","qa_group_id":"QAG:50c3d603a1b6c465ca49fd16","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"In the present study, we conducted a 2-cohort phase 2 trial in whi...
QA:17ad01938362a9428f725422
QAG:89900015a5dcce94338baf1d
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "Ramucirumab demonstrated antitumor activity and a favorable safety profile, which led to its approval in several indications, including second-line advanced G/GEJ cancer as single agent and in combination with paclitaxel"? Return the original wording with paper, Claim,...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification","cross_paper_provenance","cross_paper_provenance"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:9101e1935c3e1afe70e5e8d5","quotes":["Ramucirumab demonstrated a...
[ "CLM:9101e1935c3e1afe70e5e8d5", "CLM:3add2a9d54141ff5edee4d18", "CLM:07188d589c90a9f6b66a8e97", "CLM:619cf140fcdd7c535b17a748" ]
[ "PMCID:PMC7602637", "PMCID:PMC6386029", "PMCID:PMC7781732" ]
[ "SPAN:1d228c1c957dbe15dd5100b1", "SPAN:413f601150ed9386bc71b8ec", "SPAN:4ae33b94f6a1c28552744dd4" ]
[ "ASC2:0f2e011441ef90694f7c1e4d", "ASC2:286c6e807bec7aa05b904164", "ASC2:4538ac9f5c8c8bdc796884c8" ]
[ "HYP:DCH:4bee2cb72836544b4b9eda23", "HYP:DCH:e8df957b97babb3c84969240" ]
{"qa_id":"QA:17ad01938362a9428f725422","qa_group_id":"QAG:89900015a5dcce94338baf1d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"Ramucirumab demonstrated antitumor activity and a favorable safety...
QA:1e125ebf7faf2d09a9402c0f
QAG:75d5f24b38fe6ae12548d32d
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "The randomized, open-label, phase 3 KEYNOTE-061 trial aims to evaluate the efficacy and safety of pembrolizumab versus paclitaxel as second-line therapy in patients with advanced G/GEJ cancer that progressed on platinum and fluoropyrimidine-based chemotherapy"? Return ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b48cdd8015adee1a3c98cb91","quotes":["The randomized, open-label, phase 3 KEYNOTE-061 trial was designed to evalua...
[ "CLM:b48cdd8015adee1a3c98cb91", "CLM:3dd0f0d29cb356f9a00a37ce" ]
[ "PMCID:PMC10314681" ]
[ "SPAN:ae2a73fa78b64e130dd36ce6" ]
[]
[]
{"qa_id":"QA:1e125ebf7faf2d09a9402c0f","qa_group_id":"QAG:75d5f24b38fe6ae12548d32d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"The randomized, open-label, phase 3 KEYNOTE-061 trial aims to eval...
QA:1fe976fac52ab673c6643bb9
QAG:4d8d87d683ee0166dc784eee
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "gov, NCT03745-170) showed that CapeOX combined with sintilimab improved the prognosis of all unresectable advanced gastric cancer patients in first-line therapy regardless of the expression of PD-L1"? Return the original wording with paper, Claim, and Evidence Span ref...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:d1ca67e9969fc8e3a2af4dd7","quotes":["On the other hand, the ORIENT-16 trial (ClinicalTrials.gov, NCT03745-170) sh...
[ "CLM:d1ca67e9969fc8e3a2af4dd7", "CLM:07188d589c90a9f6b66a8e97" ]
[ "PMCID:PMC9491115" ]
[ "SPAN:e410b04868eb51503637f59a" ]
[]
[]
{"qa_id":"QA:1fe976fac52ab673c6643bb9","qa_group_id":"QAG:4d8d87d683ee0166dc784eee","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"gov, NCT03745-170) showed that CapeOX combined with sintilimab imp...
QA:25663562e633fdd0c0053880
QAG:4d2bd3cd2d520ac2f94b67c2
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "Conclusions Nivolumab treatment led to clinically meaningful long-term improvements in OS in patients with previously treated G/GEJ cancer"? Return the original wording with paper, Claim, and Evidence Span references. Integrated provenance requirements: return the exa...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:b18a30d65b19c982dd0c424c","quotes":["Conclusions Nivolumab treatment resulted in clinically meaningful long-term ...
[ "CLM:b18a30d65b19c982dd0c424c", "CLM:03ccfa8216f57bebab8dab3a" ]
[ "PMCID:PMC7165140" ]
[ "SPAN:d7ae4a6128409fbdc8bb153e" ]
[]
[]
{"qa_id":"QA:25663562e633fdd0c0053880","qa_group_id":"QAG:4d2bd3cd2d520ac2f94b67c2","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"Conclusions Nivolumab treatment led to clinically meaningful long-...
QA:29713aed37fa1d67314a19a6
QAG:f2bed9311e862902b560878d
provenance_qa
exact_evidence_retrieval
provenance_qa
G024
en
train
Which exact source passage supports the statement "Conclusions and relevance Pembrolizumab monotherapy demonstrated promising activity and manageable safety in patients with advanced gastric or gastroesophageal junction cancer who had previously received at least 2 lines of treatment"? Return the original wording with ...
{"answer_type":"integrated_provenance","embedded_answer_types":["exact_evidence_retrieval","claim_evidence_verification"],"exact_evidence_retrieval":{"answer_type":"exact_evidence_retrieval","claim_id":"CLM:dbbcc9e09339a0079c59d807","quotes":["Conclusions and relevance Pembrolizumab monotherapy demonstrated promising a...
[ "CLM:dbbcc9e09339a0079c59d807", "CLM:07188d589c90a9f6b66a8e97" ]
[ "PMCID:PMC5885175" ]
[ "SPAN:6e8aaab5860d7a34599b6098" ]
[]
[]
{"qa_id":"QA:29713aed37fa1d67314a19a6","qa_group_id":"QAG:f2bed9311e862902b560878d","qa_family":"provenance_qa","subtask_type":"exact_evidence_retrieval","language":"en","cluster_id":"G024","question":"Which exact source passage supports the statement \"Conclusions and relevance Pembrolizumab monotherapy demonstrated p...