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The flares typically last for up to 3 days at a time, and most patients are completely asymptomatic between attacks; if untreated with prophylactic colchicine, some patients later develop amyloidosis and renal failure.
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None of the patients required treatment for the overdose.
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No risk factors for rhabdomyolysis were found, but the calcium-dependent potassium efflux, normally responsible for membrane hyperpolarization and muscle refractoriness, was severely decreased in the patient's red blood cells.
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Preoperative risk factors, operative data, cardiopulmonary-bypass, postoperative complications and clinical symptoms are discussed together with ophthalmologic findings in order to elucidate the pathophysiology of this process.
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A 54-year-old woman with recurrent adenocarcinoma of the uterus was treated with new third-generation cephalosporin, cefmenoxime, for a urinary tract infection.
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A case of tuberculosis in a patient on Efalizumab and Etanercept for treatment of refractory palmopustular psoriasis and psoriatic arthritis.
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His INR was 1.69 despite the increased warfarin dosage.
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Herein we present a woman with bilateral lower extremity rest pain and a history of chronic ergot use for migraine headaches.
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For pain relief an epidural infusion at the level T1-2 with bupivacaine was started.
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P. falciparum can be transmitted in a hospital environment from patient to patient by blood inoculum if standard precautions are breached.
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Colchicine-induced rhabdomyolysis is a rare complication, and the postulated mechanisms and risk factors for this severe complication are discussed.
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Methemoglobinemia may occur in a number of drug or chemical ingestions, but a comprehensive review of the literature failed to identify a similar reported case.
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We present a 46-year-old African-American man with AIDS who was admitted on two different occasions within three weeks for signs and symptoms of meningitis after using trimethoprim/sulfamethoxazole (TMP/SMX).
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The possible underlying pharmacological mechanisms of this clinical reaction lend support to the cholinergic-adrenergic balance hypothesis of affective disorders.
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Is akathisia a forerunner of tardive dyskinesia? A clinical report with brief review of literature.
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Penile erections were regularly induced by intermittent subcutaneous injections of apomorphine in five patients with Parkinson's disease (PD) complicated by motor fluctuations.
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Propafenone is an effective antiarrhythmic drug used widely for the treatment of supraventricular and ventricular arrhythmias.
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CONCLUSIONS: The mechanism by which loop diuretics induce pancreatitis appears to be via an immunologic pathway.
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Severe hyperkalemia occurred in a patient with radiation pneumonitis and glaucoma shortly after beginning prednisone therapy.
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As ototoxicity appears to be most pronounced in the higher frequencies of sound, any changes can be assessed at an earlier stage by using high-frequency audiometry to test patients at frequencies from 8 to 20 kHz.
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The rotator cuff tendons were noted to be intact and normal in appearance.
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A 31-year-old woman developed pain, decreased vision, and a corneal flap infiltrate 4 days following laser in situ keratomileusis (LASIK).
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The patient tolerated the rechallenge with fluorouracil without complications.
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A literature review has identified only 9 additional cases.
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CONCLUSIONS: We report this case of the concomitant appearance of multiple skin cancers and nail changes associated with hydroxyurea use.
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Due to large chorioretinal scars the visual recovery was poor.
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Adverse effects of atrial fibrillation and syncope induced by calcium-channel blockers in hypertrophic cardiomyopathy.
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Tests for hepatitis A, B, and C were negative.
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Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.
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Since tamoxifen therapy can induce endometrial disorders, surveillance schemes of women taking tamoxifen have been recommended.
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We believe this represents the most delayed reported thrombosis post-sirolimus-eluting stent implantation, which might not have been preventable using even the latest FDA recommendations.
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When his carbamazepine concentration returned to previous levels, seizure control was not reestablished.
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Of note is that the renal histology at autopsy showed a remarkable improvement of mesangial hypercellularity with concomitant reduction in the number of glomerular macrophages.
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We report on a patient who presented an invalidating progressive pelvic dyskinesia while receiving different kinds of neuroleptic drugs for a psychiatric disorder.
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The histological morphology of AILD-type T-cell lymphoma shows proliferation of small, arborizing high endothelial venules.
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Adding morphine (5 mg/60 mL levobupivicaine) permitted a reduction in infusion rate.
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Dapsone (4-4-diaminodiphenyl-sulfone) is a member of the sulfone group of antibiotics used in the treatment of leprosy and various dermatitidies and more recently employed in the management of local reactions to the bite of the brown recluse spider, Loxosceles reclusa.
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Severe hepatocellular dysfunction following cyproterone acetate therapy.
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Within 4 days of discontinuing the pentamidine, the patient's heart rate stabilized at 80 beats/minute without further intervention.
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This is, to the best of our knowledge, the first report of a case in which agranulocytosis followed treatment with both propylthiouracil and methimazole in the same patient.
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Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)--a report of ten cases.
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Although a definitive causal relationship between the steroids and AI was not established, their temporal association and the exclusion of other possible etiologies led us to postulate that AI was a complication of the steroid protocol.
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Two months into his second-line chemotherapy, he developed multiple, concomitant, transverse and longitudinal black lines in all of his fingernails and toenails.
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Methylphenidate is a potent central nervous system stimulant that exerts its effects by increasing synaptic levels of dopamine and norepinephrine.
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Toxic hepatitis induced by disulfiram in a non-alcoholic.
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DISCUSSION: Drug-induced LABD is a variant of classic or idiopathic LABD.
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Anaphylaxis after the injection of chymopapain occurs in about 1% of such cases.
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The relevant literature is reviewed; a case history is presented; and implications for nursing care (e.g., early detection) are discussed.
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CONCLUSIONS: Ovulation induction therapy with clomiphene citrate may precipitate uveitis.
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METHODS: We report the first case of orbital cellulitis following Faden operation on the medial rectus muscle.
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Gold nephropathy.
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This study underscores the risks of routinely administering protamine to susceptible individuals and the need for alternative therapies.
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Methimazole-associated cholestatic liver injury: case report and brief literature review.
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The duration of each infusion should be minimised and blood volume should be carefully monitored throughout.
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SUMMARY OF BACKGROUND DATA: Symptomatic spinal epidural lipomatosis is considered to be a rare condition usually presenting with slowly progressive cord or nerve root compression.
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Once clonidine was discontinued, the resting heart rate returned to normal.
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After successful treatment, she was given demeclocycline prophylactically and rechallenged with vinorelbine without recurrence of the syndrome.
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Herein we reported a case of reactivation of sarcoidosis occurring during the treatment of chronic hepatitis C, and we present a literature review of other centers' experiences with this problem.
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Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.
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Rhino-orbital zygomycosis is usually an aggressive, fulminant and, at times, fatal disease that requires urgent medical and surgical treatment.
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Report of two cases with evidence from serial computed tomographic brain scans.
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Histopathological findings include focal vacuolar alteration of the basal layer with cytoid bodies, dermal and intraepidermal multinucleated giant cells and a mixed chronic inflammatory infiltrate with a lichenoid pattern consisting of lymphocytes, histiocytes, eosinophils and plasma cells.
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CONCLUSIONS: Jet-injection devices might constitute a helpful method to treat those patients affected by severe human insulin-induced lipoatrophy.
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Patients were followed up clinically with slit-lamp examination for evidence of tumor disappearance or recurrence, and local and systemic side effects.
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Renal pathologic findings were consistent with minimal change nephrotic syndrome (MCNS) showing extensive foot process effacement of visceral glomerular epithelial cells (podocyte).
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CONCLUSIONS: Good visual outcome after early debridement and appropriate antibiotics was achieved.
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Sodium phenylbutyrate was added to treatment with HU in two patients, but failed to produce an increase in total Hb despite increasing Hb F levels.
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Actinomyces-like organisms were seen on cervico-vaginal smears.
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The patient underwent a dorsal laminectomy, and arachnoidal calcification and ossification was find, but the removal of the bone plaques was ineffectual in order to the subsequent course of the neurological troubles.
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These two cases of acute leukemia, which developed 3 years after diagnosis of breast cancer and initiation of chemotherapy, were characterized by trilineage dysplasia and pancytopenia, and had abnormalities of chromosomes 5 and 7: characteristics consistent with treatment-related leukemia.
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Pulmonary resection was finally performed because of acute progressive respiratory failure due to massive recurrent hemoptysis.
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Further studies on the precise association with different therapies are thus needed.
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Other causes of the disease were ruled out.
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After completion of chemotherapy the patient remained in a complete remission and free of new thromboembolic events.
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Most cases are managed by oral surgeons with only a handful of reports appearing in the otolaryngology literature.
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In conclusion, the locally prepared LC was able to control the bleeding episodes in a haemophilia A patient with high inhibitor.
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We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon.
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A patient is described who developed a rapid onset of pulmonary fibrosis following treatment with a new non-steroidal anti-inflammatory drug, nabumetone.
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Aminophylline hypersensitivity apparently due to ethylenediamine.
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The observation is consistent with reports linking psychomotor abnormalities and psychosis in severely depressed juveniles to an increased propensity for manic switching, as well as adult studies that report a greater risk of antidepressant-induced cycling in bipolar compared with unipolar affective illness.
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We report the first case of hairy cell leukemia occurring after cardiac transplantation.
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2-CdA induces lymphocytopenia, which may explain the improvement in this patient's psoriasis.
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RESULTS: In these four patients, the use of caspofungin as an additional drug to the standard trimethoprim-sulfamethoxazole regimen led to a rapid improvement and a complete cure of pneumonia.
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A case of nephrotic syndrome treated with associated cyclophosphamide and corticosteroids came to our attention after over 2 years of self-administered immunosuppressive therapy which remained unchanged and uncontrolled during this period.
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Cognitive and speech functions were specifically tested during the evaluation.
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Diltiazem therapy was discontinued, leading to resolution of fever within 48 hours.
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The patients had received anthracyclines and methotrexate, a known nephrotoxic chemotherapeutic agent.
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In conclusion, the in vitro susceptibility assay as well as nucleotide sequence of clinical isolate is important to choose appropriate antiviral agents for patients who have persistent CMV reactivation after stem cell transplantation.
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If neovascularization occurred at the site of the anastomosis, intravitreal bevacizumab (1.25 mg) was injected followed by laser photocoagulation to areas of retinal ischaemia and the area of retina anterior to the L-CRA 1 week later.
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Mycobacterium tuberculosis was isolated in a culture of peritoneal fluid, and the patient responded promptly to antituberculous therapy.
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Eosinophilic pleural effusion is defined as an effusion in which eosinophils constitute more than 10% of white blood cells.
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Five months after initiating mirtazapine therapy, she developed symptomatic hyponatremia.
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We report on the clinical phenotype and infantile development of a girl born to a 36-year-old mother.
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Acute renal failure in a patient treated by continuous povidone-iodine mediastinal irrigation.
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The other patient had one of four primary BCCs respond completely, and the remaining three respond partially.
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However, there remain questions concerning whether these drugs, especially methimazole (MMI), may be associated with aplasia cutis congenita (ACC) and how best to avoid impairment of fetal thyroid function during their use.
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Theoretically, insulin-sensitizing thiazolidinediones (TZDs) should be beneficial in this patient population.
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One of the mainstay pharmacologic therapies for ADHD has been stimulants.
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Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer.
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A 42-year old woman with neck pain was prescribed 15 g of 'maqianzi' to be taken in two doses at 7 hours apart, although the recommended dose was 0.3-0.6 g.
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