ids stringlengths 6 10 | seqs stringlengths 11 1.02k | texts stringlengths 108 11.1k |
|---|---|---|
P29346 | MTISINEYSDLNNLAFGLGQDVSQDLKELVKVASIFMPDSKIHKWLIDTRLEEVVTDLNLRYELKSVITNTPISVTWKQLTGTRTKREANSLVQAVFPGQCSRLAIVDWAAKNYVSVAVAFGLLKFHRADKTFTISEIGIQAVKLYDSEELAELDKFLYERLLEYPYAAWLIRLLGNQPSKQFSKFDLGEHFGFIDELGFETAPIEIFLNGLAQAEIDGDKTAAQKIKSNFESTSDKYMRWLAGVLVTAGLATSTTKKVTHTYKNRKFELTLGTVYQITAKGLTALKEVNGKSRYPRSRKRVMWEFLATKDKEAIAKKTS... | Function: An S subtype restriction enzyme that recognizes the double-stranded sequences 5'-GGATG-3' and 3'-CATCC-5' and cleaves respectively 15 bases after G-1 and 14 bases before C-1.
Catalytic Activity: Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
Sequence Ma... |
P34880 | MQRLSPGEFKTLISKERKSHFITPFALVYKTFCDLGYDQKNSDYFLNNPSEYIIAMRKNCWKEFEPFEKEFTTRMLSYLIDEERIKDMSPYDAIRDFTMEYPTHIYDLALSNTQSRRSRAGKEFESILELLMMGAGIPVDVQGAIGKSFFQKNQIGKLVDLVMPGVVQYTSNKRNTMLISAKTTLRERWQEVPEEVNRTGIREMYLATLDDSFSEETINILYEANVVVVTTIENKNFKYKNNNRVLTFEDMLQSAMELSRKWNNVSYTDSEKEEIQRSILKQIEKYSDFPYVVNYYRNRLSALFD | Function: A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CCNGG-3' and cleaves before C-1.
Catalytic Activity: Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
Sequence Mass (Da): 35939
Sequence Length: 305
EC: 3.1.21.4
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Q9SR34 | MENIKNPKNADDCSDSISKNSHQGVDDSLNQSRSYVCSFCIRGFSNAQALGGHMNIHRRDRAKLRQKLMEDNKDDVVAESDASEVVSLDLNEQQQQQGEALTCDDHDQYVDNDISPKQKLEFWVQESKLDTNDHGKVTEASIDGSSSSHHRDIEVLDLELRLGQSVVKKKTT | Function: Activation factor which mediates telomerase activity and potentiates responses to auxin through the regulation of BT2. Binds in vitro to the DNA sequence 5'-GACAGTGTTAC-3' of the BT2 promoter.
Sequence Mass (Da): 19331
Sequence Length: 172
Domain: Contains a slightly degenerated ERF-associated amphiphilic rep... |
P34070 | DSGSSRDPGASSGGC | Function: Tremerogen A-I is produced by the a mating-type cells and induces formation of conjugation tubes in a mating-type cells.
Location Topology: Lipid-anchor
Sequence Mass (Da): 1339
Sequence Length: 15
Subcellular Location: Cell membrane
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P0CF14 | KKVYSFLKLKGCLPRNRFCNALSGPRCCSGLRCKELSIWASKCL | Function: Insect active toxin causing rapid but reversible paralysis in crickets. No activity shown in mammals. Does not show effect on mammalian voltage-gated calcium channels (By similarity).
Sequence Mass (Da): 4979
Sequence Length: 44
Domain: The presence of a 'disulfide through disulfide knot' structurally defines... |
Q9NYW7 | MLESHLIIYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSANCAILLFINELELWLATWLGVFYCAKVASVRHPLFIWLKMRISKLVPWMILGSLLYVSMICVFHSKYAGFMVPYFLRKFFSQNATIQKEDTLAIQIFSFVAEFSVPLLIFLFAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFLILYFSHCMIKVFLSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHSKCCQ | Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Location Topol... |
Q9NYW6 | MMGLTEGVFLILSGTQFTLGILVNCFIELVNGSSWFKTKRMSLSDFIITTLALLRIILLCIILTDSFLIEFSPNTHDSGIIMQIIDVSWTFTNHLSIWLATCLGVLYCLKIASFSHPTFLWLKWRVSRVMVWMLLGALLLSCGSTASLINEFKLYSVFRGIEATRNVTEHFRKKRSEYYLIHVLGTLWYLPPLIVSLASYSLLIFSLGRHTRQMLQNGTSSRDPTTEAHKRAIRIILSFFFLFLLYFLAFLIASFGNFLPKTKMAKMIGEVMTMFYPAGHSFILILGNSKLKQTFVVMLRCESGHLKPGSKGPIFS | Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 35915
Sequence Length: 316
Subcellular Locatio... |
Q7TQA7 | MFGFIEGVFLVLTITEFILGNLVNGFIVSINSSYWFKSKKISLSNFIITSLALFRIFLLWIIFIDSLIIVFSYQTHDSGIMMQLIDVFWTFTNHFSIWLISCLSVFYCLKIASFSHPSFLWLKWRASRVVVGMLWGALLLSCVSTMSLMNEFKIYSALTRSKDTPNMTEYIRLKRQEYNLMHVLGNLWKIPSLIVSLVAYLLLLLSLGKHTQQMQQYSIDSRDQSAEAHKRAMRIISSFLLFFLFYFLSFMILSSSRFLPETRIARIIGVVISMSYLVGDSFILIVCNNKLKHTFVAMLPCECGHLKPGSKGPSAS | Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 36289
Sequence Length: 316
Sub... |
Q9U8X3 | MKLQNTLILIGCLFLMGAMIGDAYSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRY | Function: Exhibits stronger antimicrobial activity against the Gram-positive bacteria (S.aureus (IC(50)=4.2 ug/ml)) and fungi (C.albicans (IC(50)=3.0 ug/ml) and P.pastoris (IC(50)=0.5 ug/ml)) than Gram-negative bacteria (E.coli (IC(50)=25 ug/ml)) . Binds to chitin (8.4 uM are required to obtain 50% of binding) . Does n... |
Q05B45 | MHPPPPGPLGDCLRDWEELQQDFHGIQETHRLYRLKLEELTKLQNSCTSSITRQKKRLQELALVLRKCKPSLPSEAEEAARELENQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLG... | Function: Ion channel involved in sensing mechanical pain. Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli. May also be required for efficient adipogenesis.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 40730
Sequence Length: 343
Subcellular Location:... |
A3KNK1 | MLFNPTGLTECLQEWEDLEKDYQQIQDTHRHYKHKLEEVSKLQESCSSSIARQRKKLKDLSESLEECKGAVNPEDVNKIDDIQESIKERPNVFFEMEAFLPKKNGLYLSLVLGNVNVTLLNKQSKFAYKDEYEKFKLYLTVLLLFFSFTCRFLVSYRVVDALFNFLLVWYYCTLTIRESILINNGSKIKGWWVFQHYVSTFLSGVMLTWPDGELYQMFRNQFLSYSMYINFVQFFQYYYQSGCLYRLRALGERHNMDLTVEGFQSWMWRGLTFLLPFLFLGHFFQLYNGITLFQMTQLPEWKEWQVLMCGSTFLVLFMGN... | Function: Ion channel involved in sensing mechanical pain. Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli. May also be required for efficient adipogenesis.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 40684
Sequence Length: 341
Subcellular Location:... |
Q9BXJ8 | MQPPPPGPLGDCLRDWEDLQQDFQNIQETHRLYRLKLEELTKLQNNCTSSITRQKKRLQELALALKKCKPSLPAEAEGAAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLAQDPQCKEWQVLMCGFPFLLLFLG... | Function: Ion channel involved in sensing mechanical pain. Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli (By similarity). May also be required for efficient adipogenesis .
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 40610
Sequence Length: 343
Subc... |
Q8C1E7 | MQSPPPDPLGDCLRNWEDLQQDFQGIQETHRLYRLKLEELTKLQANCTNSITRQKKRLQELALVLKKCRPSLPSESMEAAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLG... | Function: Ion channel involved in sensing mechanical pain . Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli . May also be required for efficient adipogenesis .
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 40751
Sequence Length: 343
Subcellular Locati... |
P0C1Z8 | YVSCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF | Function: Exhibits stronger antimicrobial activity against the Gram-positive bacteria (S.aureus (IC(50) is 7.4 ug/ml)) and fungi (C.albicans (IC(50) is 3.0 ug/ml) and P.pastoris (IC(50) is 0.1 ug/ml)) than Gram-negative bacteria (E.coli no inhibition at 100 ug/ml). Binds to chitin (4.3 uM are required to obtain 50% of ... |
O75410 | MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKL... | Function: Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways . Might promote the nuclear localization of the receptors . Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
PTM:... |
Q9PTG8 | MSLQIINDENAGNDITAEKFDLLLNPQTTGRPSILRPSQKDNLPPKPALKSTKVTFQTPMRDPQTLRIMTPSVANKPENVFLLEDCTQALEQLHLSLPSSCGPNPVEINVSVSNNQPDSEELPVRTTGAYSIDFDNFDDINPFKSKTQMLNSPIKADLPSLTENIETTTPVVPADEASKQMVSLNLSAANLDSPVTVQFSSESGSIGVSEKTALDDTLPLSESGIKDLQGLNASSNNIEEPVPLDKDICSNNEKDDATMADSTCEGTSDAHTSSNNIEEPVTLDKDICSSNEKDNAAVADSTCEGTSDAQSPLPIPKSSY... | Function: Maternal RNA in oocytes remains in a dormant state as masking outcompetes eif4g to bind eif4e, thereby preventing translation. During oocyte maturation this complex dissolves and eif4g binds eif4e to allow translation of maternal RNAs . Plays a role in the microtubule-dependent coupling of the nucleus and the... |
P09758 | MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGSGMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNRRKSGKYKKVEIKELGELRKE... | Function: May function as a growth factor receptor.
PTM: The N-terminus is blocked.
Location Topology: Single-pass type I membrane protein
Sequence Mass (Da): 35709
Sequence Length: 323
Subcellular Location: Membrane
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Q8BGV3 | MARGLDLAPLLLLLLAMATRFCTAQSNCTCPTNKMTVCDTNGPGGVCQCRAMGSQVLVDCSTLTSKCLLLKARMSARKSGRSLVMPSEHAILDNDGLYDPECDDKGRFKARQCNQTSVCWCVNSVGVRRTDKGDQSLRCDEVVRTHHILIELRHRPTDRAFNHSDLDSELRRLFQERYKLHPSFLSAVHYEEPTIQIELRQNASQKGLRDVDIADAAYYFERDIKGESLFMGRRGLDVQVRGEPLHVERTLIYYLDEKPPQFSMKRLTAGVIAVIAVVSVAVVAGVVVLVVTKRRKSGKYKKVELKELGEMRSEPSL | Function: May function as a growth factor receptor.
Location Topology: Single-pass type I membrane protein
Sequence Mass (Da): 35574
Sequence Length: 317
Subcellular Location: Membrane
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Q27272 | MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKTIDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN | Function: TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
Sequence Mass (Da): 29314
Sequence Length: 278
Domain: The C-terminus is important for mediating interaction with e(y)2.
Subcellular Location: Nucleus
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P53228 | MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDSTTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSGKDYTAETDPGVLSVKKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLNSESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSA... | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 37254
Sequence Length: 333
Pathway: Carbohydrate degradation; p... |
Q8ZN83 | MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGLEQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVDKSRILIKLAATWEGIRAAGQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYETIVMGASFRRTEQILALTGCDRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 35592
Sequence Length: 316
Pathway: Carbohydrate degradation; p... |
Q8FLD1 | MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 35205
Sequence Length: 317
Pathway: Carbohydrate degradation; p... |
Q1CZW4 | MKFFIDSADVEEIRKAHAMGCVDGVTTNPSLLAKVGRGLEETIREICSIVDGPISAECVSMEADELIKEGRSLAKIHDNVVVKIPMGVEGMKATKALTAEGIRTNVTLCFSANQALLCAKAGATYVSPFVGRLDDISQDGMELISHILEIYRNYEHFNTQVLVASVRNPVHVLQAARLGADVATLPYNVITQLANHPLTDAGIKKFLADWEKVPKAAKPPAAK | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 24082
Sequence Length: 223
Pathway: Carbohydrate degradation; p... |
Q5F6E9 | MTILSDVKALGQQIWLDNLSRSLVQSGELAQMLKQGVCGVTSNPAIFQKAFAGDALYADEVAALKRQNLSPKQRYETMAVADVRAACDVCLAEHESTGGKTGFVSLEVSPELAKDAQGTVEEARRLHAAIARKNAMIKVPATDAGIDALETLVSDGISVNLTLLFSRAQTLKAYAAYARGIAKRLAAGQSVAHIQVVASFFISRVDSALDATLPDRLKGKTAIALAKAAYQDWEQYFTAPEFAALEAQGANRVQLLWASTGVKNPAYPDTLYVDSLIGVHTVNTVPDATLKAFIDHGTAKATLTESADEARARLAEIAAL... | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 37502
Sequence Length: 351
Pathway: Carbohydrate degradation; p... |
A9A413 | MKIFLDTANLESIKKFNDMGLLDGITTNPSLMSKEKGNPKDAMEEITKIIKGDVSLEVVSTDFSGMVDEGKRLRQYGDNVVVKVPMTPDGLKACKSLSSEGIPVNVTLVFSPNQALLAAKSGAKYVSPFIGRLDDIGQDGMNLIQDIKDIFKNYPHLKTEILVASVRHPMHVVEAAKIGADVVTLPPGVLDKMLQHPLTKIGLENFLKDWEKVKAENPDIKI | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 24341
Sequence Length: 222
Pathway: Carbohydrate degradation; p... |
Q8D1X3 | MNQLDYIKKFTNVVIDSGNIKYIKKYSPKDVTTNPSLILRESKSKHYYPLLMDAISYAKKKGGNLNSYIINANDKLLVNIGREILKIIDGRISIEIDVRLSFSYLDLIIRAKKIISLYNSYGIENNRILIKIAATWEGIQAAKFLEKSGINCNLTLIFSLVQAIACAESNVYLISPFVGRVNDWYIKNFKLNKNSKIDPGVKLVYKIFYFYQKYGYKTFVMGASFRNIDQIISIIGCDAITISPDFVNKLNNLKLKKIKNFIRVNLESKIKKNKLLEKEFRWKFNQNFMAVEKLSEGIRLFLRDQKKIDSFFLKKFKSG | Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Catalytic Activity: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate
Sequence Mass (Da): 36964
Sequence Length: 319
Pathway: Carbohydrate degradation; p... |
P45791 | MKKQSGFTLIELMIVVAIVAILAAIALPAYQTYTKKAKFTEVVSATGTYKSALEVCFQTVGSLLNCTNGTNGVPPAAGASGLVTSVAVSGNTASAATITATGDATTFGATSNVYIMTAAGSNGQIIWTAPASGSTCAGAGFC | Function: Major component of the type IV (TAP) pilus . Aeromonas hydrophila possesses two distinct families of type IV pili: the bundle-forming pilus (Bfp) and the type IV pilus (Tap) .
Location Topology: Single-pass membrane protein
Sequence Mass (Da): 14069
Sequence Length: 142
Subcellular Location: Membrane
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P45793 | MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAIVSRQITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPRHFDALYCDLVEAGEQSGALETIYDRIATYREKSEALKSKIKKAMFYPAMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQHWWYVIFGGTAFAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR... | Function: Involved in the translocation of the type IV pilin.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 45386
Sequence Length: 413
Subcellular Location: Cell inner membrane
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A2BIE7 | MADSVAAGLGDENETENEDKEREKRLFSGVKKMEKQAAASDVTETLGFYERKAKCKDRKTNVSDLSLVRFISAELTRGYFLEHNEAKYTERRERVYTCLRIPKELEKLMIFGYFLCLDVFLYVFTLLPLRVLLALVRLLTLPCCGLSGSRILQPAQVCDVLKGFIMVLCYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYTLLLIVCLR... | Function: Plays a role in primary cilia formation . Involved in cartilage and bone development . May play a role in the differentiation of cranial neural crest cells . May act as a downstream effector of hoxc8 during development (By similarity).
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 64778
S... |
Q6NXT6 | MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETLGFYESDRRRERRRGRTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLRDRRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIV... | Function: Plays a role in primary cilia formation . May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in... |
A0A0F7GFI5 | MTVSNKTQTALVGSPDGAIILSDTAPLPPSQLEDEQVAVAVQAVSLNPVDTKMAGDYHTPGAISGCEFAGVVTAVGPGAASEWGLGPGDRVSAAIMGMNPLRPSIGAFAQHSVAPAHCLLKMRDDWGFAQAAGLGNSWYTVAWALFHVMGLPAGPELEPLHTKHPPPAREPRISIDNPAPNGGGGKRTTVLVSGGSSSTGTCAIQLLKLAGFDVVATSSARNFDLVRSYGADAVFDHSSPSVAADIKAHTRNGLRLALDCITTPDTTRLCYGAIGRTGGRYVSLDPYSEVVAASRAVVRADWVLGPELMGEDVGWPAPHG... | Function: Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of the tetramic acids Sch210971 and Sch210972, potential anti-HIV fungal natural product that contain a decalin core . The PKS module of tasS together with the enoylreductase tasC catalyze the formation of the polyketide unit which... |
A0A0F7CUE9 | MFFDSVTNGPEDVMYQVKAACDSDNDPSKIDLGVGTYRNEDGDYHELDVLKEIATVQTISGTGAIHIGAMFLARSATDVLPHVYVGTPTWGNYQPLLRLAGLEMRTYNHYLSQTGRVDFASVLSAIRTTPRGSTFILQGCCHNPTAADFSREQWDIVVAEMESHGHLPFFDIAYQGLGEGVDEDVYGVRLCADKGMEMVVCQSFAKNFGLYGERCGALHVVCTSDDVAARVKDQLRCLIRWEFSSSPAYGARLVNLVLSDARAEEQCLLPLSKTQCQELQNKFRIYAVPNGRITMSGLSQGNIDYAARAIDAVVRSGLEA... | Function: Aminotransferase; part of the gene cluster that mediates the biosynthesis of the tetramic acids Sch210971 and Sch210972, potential anti-HIV fungal natural product that contain a decalin core . The PKS module of tasS together with the enoylreductase tasC catalyze the formation of the polyketide unit which is t... |
A0A0F7CUE8 | MRSMSLWMLIGPVTGIATWASLRYAATTTTSSTAAASTRMGLAPVIALSHGGGPLPLLGDPGHKSIIHSLSHRIPKILSLNDPDRRPRAIILITAHWSTAAPTISGAANPDLIYDYYGFPPETYELKYPARGDPGIAAEAAAAFRAEGLGDVVVDPGRGWDHGVFVPMTLVRPEADIPIVQMSVLASEDPTSHLRMGRALRALRAENIAIVGSGFASFHNLRAMMAMRSSAGSRNPEGARIQAISREWNSALTDVVDKNPWQGLEGWRSLPGADLMHPPRGGEHFMPLIACAGAAHEEEKVRWYTDEYLGVDIYTYYWGG... | Cofactor: Binds 1 zinc ion per subunit.
Function: Dioxygenase; part of the gene cluster that mediates the biosynthesis of the tetramic acids Sch210971 and Sch210972, potential anti-HIV fungal natural product that contain a decalin core . The PKS module of tasS together with the enoylreductase tasC catalyze the formatio... |
A0A0F7GG06 | MDDQKGPLPPYTPTATAPPPASMRQRRPPGRRRALRRSRTVRVLALACLAFVVLAQWKQLWRGERKAPPYLSVDKLNDNLETCRKLRVRPQDPAGPGRSKNDRYLDGGGKPTLIRNALIWTGEPVPGTSDEDARAGVGWAWWLGDVLVERGLITKVDNKMPASEVPEDAIIYDAEGRRLTSGIVDMHSHAGVSPLPGLNGNDDTNEASDNITPWARSIDGLFPLDPQIQVIKSGGVTSSLILPGSANNIGGEAFLIKHAVGRHDGRPELSAASMLADPDRTWRYMKMACGENAKRVHGSRTTRPVTRMGESYDFRRAFER... | Function: Amidohydrolase; part of the gene cluster that mediates the biosynthesis of the tetramic acids Sch210971 and Sch210972, potential anti-HIV fungal natural product that contain a decalin core . The PKS module of tasS together with the enoylreductase tasC catalyze the formation of the polyketide unit which is the... |
Q32LD7 | MLSEGYLSGLAYRNDIQWSYPSSNEQVAEEKEEEMEATAAASLSYSSVDETQVQNLYVSCKSSGKVISSVYSRESQHSRNPRITVLQTNPNPVYESPNLAAVELYRDTSRETYLVPPSCKSICKNYNDLQIAGGQVMAINSATTDFPSEGSFQYGPLLKSSEIPLSMEDSMFTQPSDLPPTPIQRYSSYWRITSIKEKNSLQMQKPISNAVLNEYLEQKLVELYKQYFMDTGFHDSSPTQILASELIMTNVDQISIQVSIEKNLEISKARDIVINRLLQYGSTEISTQSLHISQYSNVNP | Function: Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IR... |
Q9HAI6 | MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP | Function: Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 . Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to I... |
Q9D3J9 | MLSEGYLSGLTYWNDIHWNCASYNEPVAGDQGKETSSVAALSYSSVDETQVQSLYVSCKSSGKFISSVHARASQHSRSQSRTVLQANSNPVFESPTLAAVGICRDVIRETYLVPPSCKSICKNYNDLHIAGGQVMAINSVMANFPSESSFEDGPLLKSSEISLSMEDSTSTQLTELPLKPIQRYSSYWRITSIKEKSSLQMQKPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASEFIMTNVDQISLQVSKEKNLDTSKVKDIVISHLLQLVSSEISTPSLHISQYSNITP | Function: Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IR... |
Q9P6N7 | MSNGLVILHAGAGLYSGQREIQAKKTCSDACKAAIQALKVGQSALSAAIQAAKIMEDSPVTNAGVGSNLNIDGKVECEAGVMDSESGLTASVACCNCCRHPSEACLYILNKRKVMSQHGLVPPAMLVGNGIEKLLLHSNIKLVPESHLITERSMKTQIKWKEILYQNPINLSSQDTIGVICVDKNGRIAVVSSSGGLLLKPAGRIGSSPIPGHGFWIESFDNKSHSSTCAVATSGTGEHISNTCFACRSSQLLVSEDNVVSSLNKLINDFHEHPSATLYSDLQVGIIFAKVETSNSHNKRIIFGLAHSSPDMVFGFMKGD... | PTM: Cleaved into an alpha and beta chain by autocatalysis; this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity (By similarity).
Sequence Mass (Da): 36833
Sequence Length: 345
Subcellular Location: Cytoplasm
EC: 3.4.25.-
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A8F2N4 | MGMSVSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDKNK | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
A5UZ79 | MPQLGMGELLIILIIVLLLFGASRITGVASALGGSIKAFRKAVRDDDVPASKSEPAESTDKKVETNV | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
Q1AUL2 | MIPANFGGTELIILLVIILLLFGAKRIPELARGLGTGVREFRKGTSGAYEELEEKKGEEEKDEGGKKEAEASGRGEEEQQARAAGEAGRKQG | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
A1AVW1 | MMPGPFELIVILVIVLLLFGGKRLKNVGSDLGNAIKGFKKSMQKEPADQINTKDNIVEAKTTKESTK | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
Q21FP8 | MGLGGISIWQLLIVLVIVLLLFGTKRLKGLGGDLGGAIKGFKKAMSDDEAAKQEAEEAEQKKVAAEEAAAAKTAEQKEKTEAK | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
A4FBZ2 | MGLPGGWELVLIVGVLVLLFGATKLPQMARSLGQSARVFKAEARGMKEDEEAAKREKQAKSEPQQLTAGESSAPTVASPVEETQRNDSKK | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
A8M2B2 | MGALKPWHIAVLVVVLILLFGAKRLPDAARSLGRSLRIIKAETKSLHDDDRDLAEKANAQAGYQPLPPQVQQEPYPQQTPYQAPPQQQPVVDPVQRARDS | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
P0A2H4 | MGGISIWQLLIVAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDDAKQDKTSQDADFTAKSIADKQGEAKKEDAKSQDKEQV | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Location Topology: Single-pass membrane protein
Sequence Mass (... |
Q4ZZG9 | MFGISFSELLLVGLVALLVLGPERLPGAARTAGLWIGRLKRSFNAIKQEVEREIGADEIRRQLHNEHILSMEDEARKMFAPNQPSENSPEPANPPPAPAAAEAASPVHNQAAHHEIGPAQPAAPKTELSLEKTAKPADAGTPVPAPPAHDSSLPPRAP | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q4FQ60 | MFDIGFSELLLFGVIALIVLGPEKLPQAARTAGQWYAKIRRTVSTLQSEIEAELDLAETRQLMQKELAKIRQTEAEMRREMAEMRGSIKEFEHSQSQNLKTSDKAASPANQANNDSAIQNNNEPATFSYAYGQSNNLTDSQQLSNQDITSINSDAVTDSSTIKQPAQPLITKPWENMWFRLGAYDKARRLPAVPYLPNYKADILLNSSFDSSFDSPLNTQASVNQQESE | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
A1SRS0 | MFDIGFWELVLISVIGLVVLGPERLPHAIRSVMHWITTAKNMANSVKTEVTQELKLHEINENMIKASKQGLSDLDPELQKSIDEMKETAEQLSRPYKKDIDDIKTSLDKNPSGTTQQENSILDSSKTTPPRQDKNE | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q2K969 | MFDIGWTELLVIAVVLIVVVGPKDLPPMLRAFGKMTQRARKVAGEFRAQFDEALREAELDDVRQTISDAQKLNPVSSLREAMNPLRQMGNEIKADLQKATAVTENKTEVPSAAMSAPTPSMSLPETPPVVPTPAPAPEPAAVAAETVAAKPKAPRKPRAKAADKAAFAIAAPVENPPAEKPKRTTAARKPAAPKTPVQTKKKKDEA | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q1MHM4 | MFDIGWTELLVIAVVLIVVVGPKDLPPMLRAFGKMTQRARKVAGDFRAQFDEALREAELDDVRQTISDAQKLNPVNSLREAMNPLRQMGNEIKADLQKATTVTENKTEVPPDAVAAPTPSMSLPETPPLVATPAPSEPVAAAVVQADTVAAKPKAVRKPRGKIADKVDAAAAVAVPVEKPKRTTAVRKPATLKKPAQTKKDEA | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q92Q24 | MLDIGWTELVVIAIVLIIVVGPKDLPPMLRAFGRMTSKMRGMASDFRRQFDEALREADLDDVRKTISDAQSLNPTAALRDAMNPLRQLGNEIKSDLQKATTPDRPPASATPEPLVEPVNTDAVGETAAKATEKVAAAAVSSASRQMDRAADVPKASEPKPAPKPRAQSKKPGTSVTKKAAGETAPKKSPARKAPGEAPAANKSKTRAASRKKGDA | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q214X1 | MFDIGWSELLVIGVVALIAIGPKELPGVLRMVGQWMGKARKMASEFQGQFNEAMREAEMADLKKSFDDIKATANTFSRDNIMTSLQKDVDAAMTIDKIEHIDTSPVEPTTPEPPTAETLLEAETHAASISAATAVTEVGEPLAITQEIHPALPSPEPAAAIAIAPIKDAKAS | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q2RTH3 | MFDLSWSEIALVGVVALIVIGPKDLPNVLRTAGKWVRKIRSLGSEFQRQMDDVMRETGAEDVRRQVTTLARTDVGRKIDQAIDPDGKLAASLSSVPPPSPAGPFGTSPAAPPSLPPQAPAQPVPPATGAAPPSPSAGPDRRTDGSLPPQD | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q163T8 | MFDLGWTEMLVIGIVALIVIGPKDLPVMFRTIGQFVGKAKGMAREFSRAMNDAAADSGVNDVTKSLKAAVNPVNTAMDSVKSAASDLGKFDPESETGKLAADKAERAQNAKKIQAATARAAADRKLKEAQEAQARASELEAAVTPPEKNET | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q5LQ14 | MFDLGWSELLVIGVVALIVVGPKDLPVLFRNVGRWVGKARGLAREFSRAMNDAADEAGVKDISKGLKAATNPVDAALDGVRKAATDFKTDLDPTKYNPDSETGKLAAERAEQAKKIQAATARVAAERRLREATAELEKAKDAEAALKPGPET | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q1GFN7 | MFDLGWTELLVIGVVALIVVGPKDLPKLFRNVGRFVGKARGMAREFSRAMEDAADEAGVSDIQKTFKTATNPMGSAMDSVKQATRDLTDSIDPTKFDPESETGKLAADRAENAKKIQAATARAAADRMAREAAEAAAKAEEAEAALSATPASTASSDSETKA | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q21FP7 | MFDIGFLELAVIAVIGLIVIGPERLPEAVRSGATWMAKIRKMMRDTRAEIEVQIGADEIRRELHNEQVMKSLEALKVTKDDIQQHILDADRKMMLEQEAEEAKLQTPVSRRVAGDDPTLGTDDNVFTDPSYAHPPEEPSKVEADTSAETPQANNQDQQPTTKTEPANDR | Function: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding... |
Q75005 | MEPVDPNLEPWNHPGSQPKTACNQCYCKKCSYHCLVCFLTKA | Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongati... |
P04608 | MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAHQNSQTHQASLSKQPTSQPRGDPTGPKE | Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongati... |
P12508 | EAETATKSCSGRQANQVSLPKQPASQPRGDPTGPKESKKKVETETETDPVN | Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongati... |
P20879 | MEPVDPSLEPWKHPGSQPKTACTNCYCKKCCLHCQVCFTTKGLGISYGRKKRRQRRRPPQDSQTHQVSLPKQPSSQQRGDPTGPKESKKKVERETETDPDN | Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongati... |
P86234 | AVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRLSVDYGKKNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKLDHKFDLMYAK | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
P09734 | MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLY... | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
P68366 | MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR... | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
Q9H853 | MRHQQTERQDPSQPLSRQHGTYRQIFHPEQLITGKEDAANNYAWGHYTIGKEFIDLLLDRIRKLADQCTGLQGFLVFHSLGRGTGSDVTSFLMEWLSVNYGKKSKLGFSIYPAPQVSTAMVQPYNSILTTHTTLEHSDCAFMVDNKAIYDICHCNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVSYLTSTSPWPPMHQSSLQKRYTTSSCWWQRLPMPALSLPTRW | PTM: Some glutamate residues at the C-terminus are polyglutamylated, resulting in polyglutamate chains on the gamma-carboxyl group. Polyglutamylation plays a key role in microtubule severing by spastin (SPAST). SPAST preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing a... |
P09643 | ADACSGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICCRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISSERAYHEQLSVAEITSSCFEPNNQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRNIQFVDWCPTGVKVGINYQPPTVVPGGDLAQVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVSEGMEEGEFAEAREDLAALEKDYEEVGTDSFEDEND... | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
P06606 | MREVVSIQIGQCGIQIGNACWELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLMSAERSAHEQHAITTLTNACFESSNMMVKCDPRA... | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
P33626 | MRECISIHIGQAGIQVGNACWELYCLEHGIQADGQMPGDKTIGGGDAEFDEGEDGDEGDEY | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
Q02245 | MREIISIHIGQAGIQVGNACWELYCLEHGIEHDGTMPSDSSVGVAHDAFNTFFSETGSGKHVPRAIFVDLEPTVIDEVRTGSYRQLFHPEQLISGKEDAANNFARGHYTVGKEIVDLCLDRVRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVLLDNEAIYDICRRSLDIERPTYTNLNRLISQIISSLTTSLRFDGAINVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVPEITNAVFEPSSMMAKCDPRHGKYMACCLMYR... | Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers a... |
Q8IZP1 | MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGP... | Function: Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.
PTM: Ubiquitinated by a CUL7-based E3 ligase, which leads to proteasomal degradation.
Location Topology: Lipid-anchor
Sequence Mass (Da): 62187
Sequence Length: 549
Subcellular Location: Cell membrane
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Q9SEZ9 | MKQTDGRERKAYLSLLYFAVILLPVFLLGCYLYNEKQLRVGQFQEFNTHNLQEHITPLQQSKEDKDKKTDLVPLEFCDVFTGKWVLDNVTHPLYKEDECEFLSEWVACTRNGRPDSKYQKWRWQPQDCSLPRFDSKLLLEKLRGKKLMFIGDSIHYNQWQSMVCMVQSVIPSGKKTLKHTAQMSIFNIEEYNATISFYWAPFLVESNADPPDKRDGKTDPVIIPNSISKHGENWKDADYLIFNTYIWWTRHSTIKVLKQESFNKGDSKEYNEIGIYIVYKQVLSTWTKWLEQNINPSQTSIFFSSMSPTHIRSSDWGFNE... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q1PFD9 | MSIQTTADSRMIQSIFQVVLVSLLVLGSVRWILDELKSKESRISKLYGFRQKEAVFVTKEDQLDESCNVFEGQWVWDNVSYPLYTEKSCPYLVKQTTCQRNGRPDSYYQNWRWKPSSCDLPRFNALKLLDVLRNKRLMFIGDSVQRSTFESMVCMVQSVIPEKKKSFHRIPPMKIFKAEEYNASIEYYWAPFIVESISDHATNHTVHKRLVKLDAIEKHSKSWEGVDVLVFESYVWWMHQPKINATYGDTSEVREYNVTTAYKMALETWAKWFKTKINSEKQKVFFTSMSPTHLWSWEWNPGSDGTCYDELYPIDKRSYW... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q9SRL3 | MTTALFSPSNRRKRRLTHFFFTVLAFILLAAFIYGHDFISFSRRSLHSPTIVHQSAIVVVVDEPPPPPPTSPPPPSPPPPSPPPPSPPPPSPPPPAFAVGKTPEGCDVFKGNWVKDWSTRPLYRESECPYIQPQLTCRTHGRPDSDYQSWRWRPDSCSLPSFNATVMLESLRGKKMMFVGDSLNRGMYVSLICLLHSQIPENSKSMDTFGSLTVFSLKDYNATIEFYWAPFLLESNSDNATVHRVSDRIVRKGSINKHGRHWRGADIVVFNTYLWWRTGFKMKILEGSFKDEKKRIVEMESEDAYRMALKTMVKWVKKNM... | Function: Probable xylan acetyltransferase that plays a role in xylan acetylation and normal deposition of secondary cell walls . Required for 2-O-monoacetylation, 3-O-monoacetylation and 2,3-O-diacetylation of xylosyl residues in xylan . Required for the formation of 3-O-acetylated, 2-O-glucoronic acid-substituted xyl... |
F4IH21 | MKPSSPISLTSSSIARKARFSPYLFTLLAFILFVSVLYGEDFMCIFGQLEPNFVLPPSRTPEKNKKSEKLAFAIGKTEESCDVFSGKWVRDEVSRPLYEEWECPYIQPQLTCQEHGRPDKDYQFWRWQPNHCDLPSFNASLMLETLRGKRMMYVGDSLNRGMFVSMICLLHRLIPEDQKSIKTNGSLTVFTAKEYNATIEFYWAPFLLESNSDDAIVHRISDRVVRKGSINKHGRHWKGVDIIIFNTYLWWMTGLKMNILQGSFDDKEKNIVEVSTEDAYRMGMKSMLRWVKNNMDRKKTRVFFTSMSPTHAKGIDWGGE... | Function: Probable xylan acetyltransferase that plays a role in xylan acetylation and normal deposition of secondary cell walls . Required for 2-O-monoacetylation, 3-O-monoacetylation and 2,3-O-diacetylation of xylosyl residues in xylan . Required for the formation of 3-O-acetylated, 2-O-glucoronic acid-substituted xyl... |
O80919 | MAKRQLLMLGIRTSFHTIAAVLVAGLIFTAVFLSRNSLPKENPQSHGVTDRGGDSGRECNLFEGKWVFDNVSYPLYKEEDCKFMSDQLACEKFGRKDLSYKFWRWQPHTCDLPRFNGTKLLERLRNKRMVYVGDSLNRGQWVSMVCMVSSVITNPKAMYMHNNGSNLITFKALEYNATIDYYWAPLLVESNSDDPTNHRFPDRIVRIQSIEKHARHWTNSDIIVFNSYLWWRMPHIKSLWGSFEKLDGIYKEVEMVRVYEMALQTLSQWLEVHVNPNITKLFFMSMSPTHERAEEWGGILNQNCYGEASLIDKEGYTGRG... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q8RXQ1 | MSQRWSRKKSRLPLAGLLFILVVTFMILFNERSIQQIHHHAASHTQNLREPSTFDFVKPNVPRINYLGAHEVLDRFSKCNSTKEYSGKKIGWVDPFEDHPGQVTKEEQKCDVFSGKWVFDNSSSYPLHKESQCPYMSDQLACQKHGRKDLEYQHWRWQPHACNLKRWNAIEMWEKLRGKRLMFVGDSLNRGQWISMVCLLQSVIPRDKQSMSPNAHLTIFRAEDYNATVEFLWAPLLVESNSDDPVNHRLSERIIRPDSVLKHASKWQHADILIFNTYLWWRQDSVKLRWSSEEKGSCEEVKSAEGMEMAMDSWGDWVAN... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q940H3 | MATSETRVLFLSLCLILGKVVLSQFDELWLVGDDDPLNALQTRRERREERCDYSVGKWTFDETYPLYDSSCPYLSSALSCQRNGRPDSYYQKWRWIPKACSLPRFDALKFLGKMRGKRIMLVGDSMMRNQWESLVCLVQSVLPTHRKKLTYNGPTMSFHSLDFETSIEFCWAPLLVELKRGVDRKRVLHLDSIEDNARYWRGVDVLVFDSAHWWTHSQRWSSWDYYMDGNKIFKAMDPMVAYERGLTTWAKWVEINLDPSKTKVIFRTVSPRESGQMCYNQKHPLPSLSSSTKPHVPQQSRVLNKVLRTMKYRVYLYDIT... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
O22960 | MGFKLNSLFLLLSLLILTILSGADQALAYVKKPHVSQRNKTALAAVAGRGGGKEMLKGRKQTSGCNLFQGRWVFDASYPFYDSSTCPFIDGEFDCLKFGRPDKQFLKYSWQPDSCTVPRFDGEAFLKKWRGKRVMFVGDSLSLNMWESLACMIHSSVPNTKTTFLKRTPLSSLTFQEYDVTLFLYRTPYLVDISKESVGRVLNLGAIEDGADAWKNMDLLVFNSWHWWTHTGVQSQGWDFIRDGSSLMRDMDRLDAFNKGLTTWGQWVDQNVNVSQTRVFFQGISPTHYMGREWNEPRKTCNGQMQPLTGSTYPGGSLPA... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q9SIN2 | MGFTSRGNPSFLFFFFFFLCLSTVSAYINSTSSNNDEVRRELASGRCNWFRGNWVYDVKYPLYDPYKCPFIDPQFNCKKYGRPDNAYLKYRWQPSSCSLPRFNGLYFLRRMRGKKIMFVGDSLSTNMWQSLACLIHSWVPNTRYTLIRQKGLASLTFEEYGVTLLLYRTQFLVDLNVEKVGRVLKLDSIKQGNMWRGMDVLIFNSWHWWTHTEHIQPWDYMEDGNRLYKDMNRLVAFYKGMTTWARWVNAYVDPSKTKVFFNGVSPTHYEGKDWGEPMNSCRSQTQPFYGRKYPGGTPMAWVILNKVMRRLKKPVHWLDI... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q8LED3 | MSFLIPNRGVGGTKIPLSIIVLVLCGFMFFILLYTERISLLSSSSSSSSSFFKLKSCPRKDVSSKPKEKIRKERSEILEVLDDRFEFDPEECNVAAGKWVYNSSIEPLYTDRSCPYIDRQFSCMKNGQPETDYLRWEWQPDDCTIPRFSPKLAMNKLRGKRLLFVGDSLQRSQWESFVCLVESIIPEGEKSMKRSQKYFVFKAKEYNATIEFYWAPYIVESNTDIPVISDPKKRIVKVDSVKDRAKFWEGADILVFNTYVWWMSGLRMKALWGSFGNGESGAEALDTQVAYRLGLKTWANWVDSTVDPNKTRVFFTTMSP... | Function: Involved in secondary cell wall cellulose deposition. Required for normal stem development . May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wa... |
Q67XC4 | MGLCFQLNLASLSLILFSSFPGLLAQSQQHFLGQNNTSLLSGGRCNLARGKWVYDSSYPLYSAFSCPFIDSEFNCQKAGRPDTNYQHFRWQPFSCPLPRFDGANFMRRMRGKKIMMVGDSLSLNMFESLACLLHASLPNAKYSLRRSQPLTSLTFQDYGVTINLYRTQFLVDVVQEKAGRVLVLDSIKQADAWLGMDVLIFNSWHWWTHTSGLQPWDYMREGNQLYKDMNRLVAYYKGLNTWARWINNNIVPSRTQVFFQGVSPVHYDGREWNEPLKSCNGQTQPFMGQRYPGGLPLGWVVVNKVLSRIRKPVHLLDLTT... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
F4IWA8 | MGSKDNAISNDSALVLSLLLLLLLPLLHEAAEGCDMFTGRWVKDDSYPLYNSSTCPFIRHEFSCQRNGRPDLDYSTFRWQPLSCKLARFNGLQFLKKNKGKKIMFVGDSLSLNQWQSLACMLHSSVPNSTYTLTTQGSISTYTFKEYGLELKLDRNVYLVDIVREKIGRVLKLDSINDGKNWVEMDTLIFNTWHWWSRRGPAQPWDLIQIGTNVTKDMDRVAAFEIALGTWGKWVDTVLNTKKTRVFFQGISPSHYKGVLWGEPAAKSCVGQKEPLLGTKYPGGLPAEVGVLKRALGKISKPVTLLDITMLSLLRKDAHP... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q9ZV89 | MNFHQVLFLLLLIFLVDLSDYGVLADKTNDGYKNATKCNIYQGRWIYDNSSNPLYGTSTCPFIGLDCQKFGRPDKNYLHYRWQPTGCDIPRFNGRDFLTRFKGKKILFVGDSLSNNMWVSLSCMLHAAVPNAKYTFQLNKGLSTFTIPEYGISVNFLKNGFLVDLVSDKTRGLILKLDSISRGNQWLGSDVAIFNTFHWWSHTGRAKTWDYFQTGDKIVKEMNRMEAFKIALTTWSKWIDHNIDPSKTRVFYQGVSPVHLNGGEWGKPGKTCLGETVPVQGPSYPGRPNEGEAIVKSVIGRMAKPVELLDVTAMTEMRKD... | Function: May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Location Topology: Single-pass type II membrane protein
Sequence... |
Q9JKD8 | MGIVEPGCGDMLTGTEPMPSDEGRGPGADQQHRFFYPEPGAQDPTDRRAGSSLGTPYSGGALVPAAPGRFLGSFAYPPRAQVAGFPGPGEFFPPPAGAEGYPPVDGYPAPDPRAGLYPGPREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACSASNTHVFTFQETQFIAVTAYQNAEITQLKIDNNPFA... | Function: Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs. Activates transcription of a set of genes important for Th1 cell function, including those encoding ... |
Q9IBC8 | MRDPAFPGAAMAYHPFHAPRAADFPMSAFLAAAQPSFFPALTLPPAALGKPLSDASLAGAAEAGLHLSALGHHHQAAHLRSLKSLEPEEEVEDDPKVNLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLSLPSLRMYEEQCKADRDGAESDASSCDPAPG... | Function: Transcription factor which acts as a transcriptional repressor (By similarity). May also function as a transcriptional activator (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes (By similarity).
... |
Q19691 | MAFNPFALGRPDLLLPFMGAGVGGPGAGGPPPNLFFSMLQAGFPPGPVGSPPEDDGVTDDPKVELDERELWQQFSQCGTEMVITKSGRRIFPAYRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAGKADPEMPKTLYIHPDSPSTGEHWMSKGANFHKLKLTNNISDKHGYTILNSMHKYQPRLHVVRCADRHNLMYSTFRTFVFRETEFIAVTAYQNEKVTELKIENNPFAKGFRDAGAGKREKKRQLHRMNGDATQSPPGKTASLPTHSPHPSESNSEDDEPTLKKCKPEPSQTPTTSSLSTSTTPTLSAHH... | Function: Involved in the transcriptional regulation of genes required for the development of pharyngeal muscles derived from the ABa lineage . Acts as a transcriptional repressor and binds to T-box binding sites in its own promoter to negatively autoregulate its own expression in neurons, seam cells and the gut in ord... |
Q60707 | MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALGKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPTLRLYEEHCKPERDGAES... | Function: Transcription factor which acts as a transcriptional repressor . May also function as a transcriptional activator . Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes . Required for cardiac atrioventricular canal f... |
O74428 | MERPSLSRRTSSSTVSTDGEGVYSRSTKERKRNFIVNSRLKRGGGHVRVNRSGRLGSVTMRPSALTRAHSQNPNSSLVNNSSAVSHLTKQRSLNDLHELNGPKHVAKNGLIPLTQRKPNCVWDDAPVDNDSTAGNLDSDSALPTPSVTTNEAADSSRASSPVTRVVAVHDNKKKIINSNISNAPPFNNTDVQASARPPAAGQDDSAADASTTKSSPVHNEVMAEPLPHSNNREVTQATNQPKWQIHSGSDIASEPPTLSRGNSLSLLANRKVPSTNVKKSQAELYDLGSSTSRTQQKLLIQRASSKFDIVEDDMDTNPSK... | Function: Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for growth. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by r... |
Q08921 | MVHRGRTLKSDTDVTSLNASTVSHQSKPFRQFSTRSRAKSNASFKGLRRVLTHDGTLDNDYFNKHNVSQKCKSSDALFRKRTISGLNMTALTRVKSNQGKRSASFHSPVHNTLLSPKNSSHSNTGTAGFGLKPRRSKSTQSVLSLRDAQESKKSESTTDEEVECFSEDNIEDGKVNNDKVIAEHVMPEEKKNVQQLNQNELQSPDSIDEQEEDKSGTDGKENHRAVSLPLPHLSSNNYFGESSHSIEHQKDGETSPSSIETKLNATSVINEEGQSKVTKEADIDDLSSHSQNLRASLVKAGDNISEAPYDKEKKILDVGN... | Function: Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA ge... |
Q8WWU5 | MPDVKESVPPKYPGDSEGRSCKPETSGPPQEDKSGSEDPPPFLSVTGLTETVNEVSKLSNKIGMNCDYYMEEKVLPPSSLEGKVKETVHNAFWDHLKEQLSATPPDFSCALELLKEIKEILLSLLLPRQNRLRIEIEEALDMDLLKQEAEHGALKVLYLSKYVLNMMALLCAPVRDEAVQKLENITDPVWLLRGIFQVLGRMKMDMVNYTIQSLQPHLQEHSIQYERAKFQELLNKQPSLLNHTTKWLTQAAGDLTMSPPTCPDTSDSSSVAGPSPNEAANNPEPLSPTMVLCQGFLNLLLWDLENEEFPETLLMDRTRL... | Function: Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway.
PTM: Constitutively phosphorylated on serine, threonine and tyrosine res... |
Q01755 | MPDVKERAARKEPGAAESASRESRGGNTRESASSARGTDRVGSTVARARPPSPQGPRRGAVKTAPRGPVGHGGLRTGPTSRCPQPSARAKLPSVTRGAPLPPSPGKGHLGGTPSSHRLGMTERVHDASKLDCQLEERSLSSSSLKGKVKDTMPSDFWEHLNEQLSAVPPDFSCALELLKEIKEILLSLLLPRQSRLKNEIEEALDMEFLQQQADRGDLNVSYLSKYILNMMVLLCAPIRDEAVQRLENISDPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSVQFERAQFQERLNKEPRLLNHTTKWLTQAATQLI... | Function: Plays a role in the process of sperm capacitation and acrosome reactions . Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway .
PTM: Constitutively phosphorylated on serine, threonine and tyrosine r... |
Q93Z00 | MQKPTSSILNVIMDGGDSVGGGGGDDHHRHLHHHHRPTFPFQLLGKHDPDDNHQQQPSPSSSSSLFSLHQHQQLSQSQPQSQSQKSQPQTTQKELLQTQEESAVVAAKKPPLKRASTKDRHTKVDGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPSVIAATGTGTIPANFTSLNISLRSSGSSMSLPSHFRSAASTFSPNNIFSPAMLQQQQQQQRGGGVGFHHPHLQGRAPTSSLFPGIDNFTPTTSFLNFHNPTKQEGDQDSEELNSEKKRRIQTTSDLHQQQQQHQHDQIGGYTLQSSNSGSTATA... | Function: Transcription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues . Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways th... |
P51563 | MRSSAIIALLIVGLDAMGLGLIMPVLPTLLRELVPAEQVAGHYGALLSLYALMQVVFAPMLGQLSDSYGRRPVLLASLAGAAVDYTIMASAPVLWVLYIGRLVSGVTGATGAVAASTIADSTGEGSRARWFGYMGACYGAGMIAGPALGGMLGGISAHAPFIAAALLNGFAFLLACIFLKETHHSHGGTGKPVRIKPFVLLRLDDALRGLGALFAVFFIIQLIGQVPAALWVIYGEDRFQWNTATVGLSLAAFGATHAIFQAFVTGPLSSRLGERRTLLFGMAADGTGFVLLAFATQGWMVFPILLLLAAGGVGMPALQA... | Function: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 40913
Sequence L... |
P51564 | MNKSIIIILLITVLDAIGIGLIMPVLPTLLNEFVSENSLATHYGVLLALYATMQVIFAPILGRLSDKYGRKPILLFSLLGAALDYLLMAFSTTLWMLYIGRIIAGITGATGAVCASAMSDVTPAKNRTRYFGFLGGVFGVGLIIGPMLGGLLGDISAHMPFIFAAISHSILLILSLLFFRETQKREALVANRTPENQTASNTVTVFFKKSLYFWLATYFIIQLIGQIPATIWVLFTQYRFDWNTTSIGMSLAVLGVLHIFFQAIVAGKLAQKWGEKTTIMISMSIDMMGCLLLAWIGHVWVILPALICLAAGGMGQPALQ... | Function: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 43672
Sequence L... |
O07776 | MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR | Function: Member of the three-protein two-component system HK1/HK2/TcrA.
PTM: Phosphorylated by HK2.
Sequence Mass (Da): 28170
Sequence Length: 253
Subcellular Location: Cytoplasm
|
P23054 | MNTSYSQSTLRHNQVLIWLCVLSFFSVLNEMVLNVSLPDIANEFNKLPASANWVNTAFMLTFSIGTALYGKLSDQLGIKNLLLFGIMVNGLGSIIGFVGHSFFPILILARFIQGIGAAAFPALVMVVVARYIPKENRGKAFGLIGSLVAMGEGVGPAIGGMVAHYIHWSYLLLIPTATIITVPFLIKLLKKEERIRGHIDMAGIILMSAGIVFFMLFTTSYRFSFLIISILAFFIFVQHIRKAQDPFVDPELGKNVFFVIGTLCGGLIFGTVAGFVSMVPYMMKDVHHLSTAAIGSGIIFPGTMSVIIFGYIGGLLVDRK... | Function: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 49756
Sequence L... |
O69730 | MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVMLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR | Function: Member of the two-component regulatory system TcrY/TcrX.
PTM: Phosphorylated by TcrY.
Sequence Mass (Da): 25844
Sequence Length: 234
Subcellular Location: Cytoplasm
|
O69729 | MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPV... | Function: Member of the two-component regulatory system TcrY/TcrX. Activates TcrX by phosphorylation.
PTM: Autophosphorylated.
Location Topology: Single-pass membrane protein
Catalytic Activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
Sequence Mass (Da): 50344
Sequence Length: 475
Subcellular L... |
A1JIM8 | MHIDNAITTTIETKTWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILIMLVLAYPIAFLCHRALARLCLSGSNCSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQLAPLNRGVVALALLLLMAVVIYFGKDLMVKVMSFLVFPFIACLVLISLSLIPYWNASVIEQVDLSQISLLGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEPEFGREYTEKKCSQIISRASILMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLANHFSSMAGSRSTFSITLEYAASL... | Function: Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
Catalytic Activity: H(+)(in) + L-threonine(in) = H(+)(out) + L-threonine(out)
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 48950
Sequence Length: 442
Subcellular Locati... |
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