ids
stringlengths
6
10
seqs
stringlengths
11
1.02k
texts
stringlengths
108
11.1k
P81528
VAVKATTTEEETEIPAK
Function: Hydrolyzes the cell walls of mycobacteria. May play an important role in cell wall growth and cell separation. PTM: The N-terminus is blocked. Sequence Mass (Da): 1817 Sequence Length: 17 EC: 3.2.1.-
P06653
MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK
Function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing cell walls for activity. Catalytic Activity: Hydrolyzes...
P36548
MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDELLKTSNGHSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDARLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMAKYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKLHSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYFHWFDNQKAHSKKR
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. PTM: Exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. Can also be exported by the Sec system. Cata...
P57638
MSKKITILIDAGHGGYDPGAIGIRGLKEKNINIEIALKLEKLLNHDKMFCTILTRHNDSYLSLKKRKQLLKKNQVNFLISIHADSSRKQNVSGASIWIVSKTRINREINNYLKNKSTLLFSKKIENIFKQNKNDFFLKKTILDLQSNNFQKIELDLSKEILKQLEKNTKLNKKYPNYASLGILSSINTPSILIETGFITNILEGKKLKTTNYQNKIANSIYLGLKNYFTKSSYILKK
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 27240 Sequence Length: 237 Subcellular Location: Secreted EC: 3.5.1.28
Q8K908
MIDPGHGGQDPGAINSLGLQEKKITLKIGIKLKNLLQNSDLFYPVLTRNDDSYVSLKKRRDFLKNNHVSFLISIHADSSKKRYVSGASIWITTNDRMHREINNFIKNREENIYFPKNIQNLIQKNKHDFFLKKTVLDLQFNNFQKMEINLSRYIFQQLKKIIKLDKINLNYASLGILSSINTPSMLIETGFITNFLEEKKLRTNKYQNKIANAIYIALKNYFQDRLLSNLRNT
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 27259 Sequence Length: 233 Subcellular Location: Secreted EC: 3.5.1.28
Q89A33
MIIAIDAGHGGQDPGAIGKNKFQEKNITLSIAKKLTKLLNHTNFFKAVMIRRGNYFLSVFKRTQIAEKYHANLLISIHANSSKNRKISGVSIWVLPKNVHNTRIQKHKLNKKTKNIHKKINTKTSKFKNFYEIEYDLAKIIIQELRKVSTLNQKKPKYAKFGILKFSQFPSILVETGFISNPIEEQHLNKKFYQNLISKSISIALKKYFLKRIKQYN
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 25202 Sequence Length: 217 Subcellular Location: Secreted EC: 3.5.1.28
P26365
MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFIGDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDLTENGKTEAVKRQNGSNYTVVFTINADVPPPPPPPPVVAKRVETPAVVAPRVSEPARNPFKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNVTIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRSATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQ...
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 4...
P44493
MKTKILFFLFFSTFSFSIFAAPITIAIDPGHGGKDPGAISRNLGIYEKNVTLSIAKELKALLDKDPHFRGVLTRKSDYYISVPERSEIARKFKANYLISIHADSSKSPDRRGASVWVLSNRRANDEMGQWLEDDEKRSELLGGAGKVLSHNNDKYLDQTVLDLQFGHSQRTGYVLGEHILHHFAKVTTLSRSTPQHASLGVLRSPDIPSVLVETGFLSNSEEEKKLNSQTYRRRIAYMIYEGLVAFHSGKTNTLVKDNLVQNIKQNDIKKSGKNNRTSEQNINEDNIKDSGIRHIVKKGESLGSLSNKYHVKVSDIIKLN...
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 49109 Sequence Length: 432 Domain: LysM domains are thought to be involved in peptid...
P26366
MIYRIKNAVIAALILLCAQAGAASLSDIQVSNGEQQARITLSFIGEPEYAYSQDGKRTVALDIRQTGVIQGLPLQFSGNNLVKTIRAGTPKDAQSLRLLVDLTENGKTEAVKRQNGGNYTVIFTINADVPPPPPPVVAKRVESAPRPTEPARNPFKSSDDRLTGVTSSNTVTRPAARASAGAGDKVVIAIDAGHGGQDPGAIGPGGTREKNVTIAIARKLRTLLNNDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRDATGASVWVLSNRRANSEMANWLEQHEKQSELLGGAGDVLANSQSDPYLS...
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 46790 Sequence Length: 439 Subcellular Location: Periplasm EC: 3.5.1.28
P63884
MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPASSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSARVGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLEDYNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQIARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSGSSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTM...
Function: Cell-wall hydrolase involved in septum cleavage during cell division. PTM: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain ...
Q9K0V3
MIKLTRRQIIRRTAGTLFALSPIASAVAKTVRAPQFTAARIWPSHTYTRLTLESTAALKYQHFTLDNPGRLVVDIQNANINTVLHGLSQKVMADDPFIRSIRAGQNTPTTVRLVIDLKQPTHAQVFALPPVGGFKNRLVVDLYPHGMDADDPMMALLNGSLNKTLRGSPEADLAQNTTPQPGRGRNGRRPVIMLDPGHGGEDPGAISPGGLQEKHVVLSIARETKNQLEALGYNVFMTRNEDVFIPLGVRVAKGRARRADVFVSIHADAFTSPSARGTGVYMLNTKGATSSAAKFLEQTQNNADAVGGVPTSGNRNVDTA...
Function: Cell-wall hydrolase involved in septum cleavage during cell division. Catalytic Activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. Sequence Mass (Da): 45190 Sequence Length: 416 Subcellular Location: Periplasm EC: 3.5.1.28
P0A4M7
MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYNKIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYINQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYLRFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVITQGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQYPSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGA...
Function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 55623 Sequence Length: 498 Subcellular Location: Cell membrane
Q8EI85
MALACLNSLNANAEIFSFDTRNSLNSDTLVLFHSADSTTYSLDFLPQSTQDQLNLAVADNSFSGKRGEVLEILVPSEIDAKRVLLVGIGDAKTLTPGEINALGGNIAAKLETVPQATVRVLTQGLNNAPLFGSELAHGIELRSYRYTQFKASNRVEKNYQIGVDDLSLNQKHHKNLQAVEAGVFLARDLTNAPAGNMYPESFANEARKLKSLGVKVTVLEAKDIERLNLGALAAVGKGSERPPKLVVAHWPGSKEAPIALVGKGITFDSGGYNIKATGTSIARMKSDMAGAATVLGTVKAMAIQKAPVNLVAIMPMAENM...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity). Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which...
Q6FFD8
MKFTLQSTAPQSAQHEYLLVLVTEQQLKNTADTYKINTLDTITHTSQFKSGFNEVLTLIGQAETCSYLNLVGLGDLKDLQPAKIAKLAQTIIKLVQTKFKQIHLDISALPIELHYLFALNLTQANYVFDEFKSKKSEAQLEQIHLITAQTGLTTQQLDLIQAIASGQDLARDLGNRPGNICFPEYLADQAKALAHEFPELLKVTILDEQQMADLGMNAFLAVSQGSDRPGRIITLEYNAQLEQAPVVLVGKGVTFDTGGISIKPAQGMDEMKFDMCGAASVLGTIRTLCEARLPIHVVGAVAAAENMPSGQATRPGDIVT...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferab...
B0VMG3
MKFTTYTTFPEQTSNESLWILVDSEQLQSNLNTYQINNLESILTATQFKANFNETLPLFGQLSTQPHSQLLGLGKAAELQAAKLAKLAQTIIKSAQNKFKHIAIDIAALPVEYHYLFALSLTQAAYGYDEFKSTKNEFVLQQVDLISSQTSLDENQLALVHAVQSGQSYARDLGNRPGNICFPEYLAEQALALAAEFPDLLKVTVLNEQQMADLGMYAFLAVSKGSERPGRIVTLEYQAQLEQAPVVLVGKGVTFDTGGISLKPGLGMDEMKFDMCGAASVLGTIRALCEARLPIHVVGAIAAAENMPSGKATRPGDIVT...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferab...
C1F4B7
MKTTLVSTPLAQLETELLAVFATDTAPAADMANGTQASPQVQLLTRDAALDAAVKTILASGDFKAEANETLLIHAPQGMAARRLLLVGAGKQARFTVHALRKAAGSAVRAARAKNIREATLAIPQSQGLDVTATARALGHGAAVADFDPDFYRSDRKDKSLQSLTLALPEATDANAAEAGLREGIALGESQNLTRTLVNEPGNRLTPTLLGEQAKKMCAEQGLRCQVYSSEKLHELKMGSFWSVTQGSDEPPALIVMEYTPEGAAEGPVLGLVGKGITFDSGGLSLKPADSMEKMKYDMAGAAAMIGAMRAIALLKPRIK...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferab...
P45334
MKYQAKNTALSQATDCIVLGVYENNKFSKSFNEIDQLTQGYLNDLVKSGELTGKLAQTVLLRDLQGLSAKRLLIVGCGKKGELTERQYKQIIQAVLKTLKETNTREVISYLTEIELKDRDLYWNIRFAIETIEHTNYQFDHFKSQKAETSVLESFIFNTDCAQAQQAISHANAISSGIKAARDIANMPPNICNPAYLAEQAKNLAENSTALSLKVVDEEEMAKLGMNAYLAVSKGSENRAYMSVLTFNNAPDKNAKPIVLVGKGLTFDAGGISLKPAADMDEMKYDMCGAASVFGTMKTIAQLNLPLNVIGVLAGCENLP...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity). Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which...
A1WUV1
MELKTKSGDPARQRTACVVVGVYERRRMSEAARAVDAASDGYLSHLLRRGDLEGEAGQTLLLPDCPGVRTDRVLLVGCGRERDFNERTYRKAVTAAARALEQAGTGEAILFLPELPVRGRDVAWRVAATAEILETTLYRFDTYKSDPRPPRRPLRQATLAVPRRADLRRAQPALTLGQAAGRGANFSRDLGNTPANICTPGYLGEQAEALAQRFDGVRAEILGPAELEEQGLAALLAVARGAEAPPRLVVLHYRGADDDQAPVALVGKGITFDSGGISIKPSASMDEMKYDMSGAAAVFGAVHAAAEAQLPLNLVAVIPA...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferab...
Q7VGF0
MKVSISHKNNFKGVSYQAQALLMSKSVFAKSPYAKLCKSFGFEGEGKFFLQEQALLLVCVEELGLDSIREAGASIARHFRTLPYKNVNVALNGKLDDSKAYALLLGALLGVYECVSYKTKTPPLHLKEIILLDEKNEVASESVLKKVHIVAQSVNEVREIINTIPQVATPKYLAKYAKELSKEVGNLECKILDEEALQKEKMGAFLAVNRASCNPPRLIHLSYKPKGAKKRIVLVGKGLTYDCGGLSLKPADFMVTMKADKSGGCAVMGIIKAIAQLGANIEVHSIIGAAENMIGGNAYKPDDVLYSREGKSIEVRNTDA...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferab...
O25294
MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGAHSKDNALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKPCEKTCANSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAY...
Cofactor: Binds 2 manganese ions per subunit. Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity). Catalytic Activity: Release of an N-terminal amino acid, Xaa-|-Yaa-, in which...
Q9H4A4
MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLA...
Cofactor: Binds 1 zinc ion per subunit. Function: Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (...
O09175
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLA...
Cofactor: Binds 1 zinc ion per subunit. Function: Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (...
P00811
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPP...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 41556 Sequence Length: 377 Subcellular Location: Periplasm EC: 3.5.2.6
Q48743
MKRLLAFCLLFFAALGQAKVPPPARSAADAEIQRAVAAFMQQYQVPGVAVGITVDGAERYYNYGVSSRKTQAKVGANTLFEVGSVSKTFTATLASYAQVNQQLSLADHPGKYLPEMKGHDFDKVTLLNLGTHTAGGFPMQVPTQVKTDQQLTAYFQSWHPQYPAGTKRTYANPGIGMLGVIAAKSMRMPFQKAMTGVLLPKLGLTNTYLTVPPAKMAFYAQGYDDKGQPVRMSPGALWEPTYGIKTTARDLLRFVEINLDQVKVEPKLKRAIDGTHVGYYRLGEMTQGLVWEQLPYPASETSLQANSSQKVIFESNAVAA...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 41878 Sequence Length: 385 Subcellular Location: Periplasm EC: 3.5.2.6
P94958
MKKSLSATLISALLAFSAPGFSAADNVAAVVDSTIKPLMAQQDIPGMAVAVSVKGKPYYFNYGFADVQAKQPVTENTLFELGSVSKTFTGVLGAVSVAKKEMTLNDPAEKYQPELALPQWKGITLLDLATYTAGGLPLQVPDAVKSRADLLHFYQQWQPSRKPGDMRLYANSSIGLFGALTANAAGMPYEQLLTARILAPLGLSHTFITVPESAQSQYAYGYKNKKPVRVSPGQLDAESYGVKSASKDMLRWAEMNMEPSRAGNADLEMAMYLAQTRYYKTAAINQGLGWEMYDWPQQKDMIINGVTNEVALQPHPVTDN...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 41272 Sequence Length: 379 Subcellular Location: Periplasm EC: 3.5.2.6
O69773
MDNSMKNIFRQGRLFIALSLAMTSISAFALTQQEVDDIIKPLMKQEQIPGMSVAISVNGKQAIYHYGVQSKQTQIPVSDRTLYEIGSLSKTFTATLATYAQIQGKLDFSQSVSHYLPELKGSAFDNVSVMNLATHTSGLSLFVPSDIKTNDQLMAYYQKWLPDNEVGQYRSYSNLGVGLLGIVTAKQLNMPFSQAMEKLMLPSLGLKHTYIHVPKSQEKYYAQGYNKQNQPVRLNLEILGPEAYGLKSNAKDLIRYLEINMQSIKVAKTWQEAIENTHTGVYLTDSFVQDMMWESYPWPVSLSQLLQGNRDDMALKPQKV...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 43366 Sequence Length: 384 Subcellular Location: Periplasm EC: 3.5.2.6
P24735
MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMAL...
Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 43401 Sequence Length: 397 Subcellular Location: Periplasm EC: 3.5.2.6
P85302
ATDIRQVVDSTVEPLMQQQDIAGLSVAVIQNGKAQYFNYGVANKDSKQPITENTLFEIGSVSKTFTATLAGYALANGKLKLSDPASQYLPALRGDKFDHISLLNLGTYTAGGLPLQFPEESDNTGKMISYYQHWKPAFAPGTQRLYSNPSIGLFGHLAAQSLGQPFEKLMEQTVLPKLGLKHTFISVPETQMSLYAQGYDKAGKPVRVSPGALDAEAYGIKTSTSDLIHYVEVNMHPAKLEKPLQQAIAATHTGYYTVDGMTQGLGWEMYPYPIKVDALVEGNSTQMAMEPHKVNWLTPPQAAPLDTLVNKTGSTGGFGA...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 38728 Sequence Length: 358 Subcellular Location: Periplasm EC: 3.5.2.6
O05465
MKLFTSTLTAKKSSTHKPLISLALSVLISTLLISETAQAADANDRLEQEVDKQAKQLMAQYQIPGMAFGIIVDGKSHFYNYGLADKQRNQPVSEDTIFELGSVSKTFAATLASYSELNGTLSLDDTADKYIPYLKNSAIGNTKLISLVTYSAGGYHYRCLKTLENNKELLQYYKSWHPDFPVNSKRLYSNASIGLFGYISALSMHSDYTKLIENTVLPSLKMTNTFVDVPANKMEDYAFGYNAAGEPIRVNPGMLDAEAYGIKSTSADMTRFMAANMGLVTVDSQMQQALDNNRKGYYRTKSFTQGLAWEMYPLPTTLQQ...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 44451 Sequence Length: 401 Subcellular Location: Secreted EC: 3.5.2.6
P18539
MTKMNRCAALIAALILPTAHAAQQQDIDAVIQPLMKKYGVPGMAIAVSVDGKQQIYPYGVASKQTGKPITEQTLFEVGSLSKTFTATLAVYAQQQSKLSFKDPASHYLPDVRGSAFDGVSLLNLATHTSGLPLFVPDDVTNNAQLMAYYRAWQPKHPAGSYRVYSNLGIGMLGMIAAKSLDQPFIQAMEQGMLPALGMSHTYVQVPAAQMANYAQGYSKDDKPVRVNPGPLDAESYGIKSNARDLIRYLDANLQQVKVASVARRWPRRTSVITSAGAFTQDLMWENYPYPVKLSRLIEGNNAGMIMNGTPATAITPPQPE...
Function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. Catalytic Activity: a beta-lactam + H2O = a substituted beta-amino acid Sequence Mass (Da): 41096 Sequence Length: 376 Subcellular Location: Periplasm EC: 3.5.2.6
P81073
MNQKHLLRFIKKSYRVDADRVVYDAK
Function: AMP deaminase plays a critical role in energy metabolism. Catalytic Activity: AMP + H(+) + H2O = IMP + NH4(+) Sequence Mass (Da): 3195 Sequence Length: 26 Pathway: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1. EC: 3.5.4.6
P23109
MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIK...
Cofactor: Binds 1 zinc ion per subunit. Function: AMP deaminase plays a critical role in energy metabolism. Catalytic Activity: AMP + H(+) + H2O = IMP + NH4(+) Sequence Mass (Da): 86490 Sequence Length: 747 Pathway: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1. EC: 3.5.4.6
P10759
MPLFKLTGQGKQIDDAMRSFAEKVFASEVKDEGGRHEISPFDVDEICPISLREMQAHIFHMENLSMSMDGRRKRRFQGRKTVNLSIPQSETSSTKLSHIEEFISSSPTYESVPDFQRVQITGDYASGVTVEDFEVVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEALVAIESFYPVFTPPPKKGEDPFRREDLPANLGYHLKMKGGVIYIYPDEAAASRDEPKPYPYPNLDDFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIK...
Cofactor: Binds 1 zinc ion per subunit. Function: AMP deaminase plays a critical role in energy metabolism. Catalytic Activity: AMP + H(+) + H2O = IMP + NH4(+) Sequence Mass (Da): 86432 Sequence Length: 747 Pathway: Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1. EC: 3.5.4.6
P0A3Z3
MSNRRKNSLYPTLSAELSALMRTGWADTERHDLAPAEQAPYAALRRAALSARFPGERLVVPSGNLKVRSNDDTYPFRSYSGYVHMTGDQARDGALVLEPRPDGGHDAYCYQLPRDSRDDDEFWTGAHAELWTGRRRSLAESERVLGLPCRDVRTAAADLAAVSEVRTRIVRGIDPALEAAVTTDEERDAELEDALSDLRLVKDAWELGELRKAVDSTVRGFTDVVGELSRAVASSERWLEGTFFRRARLEGNAVGYGTICAAGEHATIMHWTDNDGPVRPGDLLLLDAGVETRSLYTADVTRTLPISGTFTPLQREVYDA...
Cofactor: Binds 2 manganese ions per subunit. Catalytic Activity: Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Sequence Mass (Da): 51925 Sequence Length: 470 EC: 3.4.11.9
D5GHP2
MTSDSTVDKILAGKYPAKQHAENVVERLLHVHPDLTDGVIYLESQRSKLYENSDQEVPFRQRRYFYYLSGCDLADSYLTYSIRDRKLTLFIPPIDPASVLWSGLPLSNSEALEKYDVDEVLPTSATALPTTSYSSLMFVIESQTSRTFHLQNTESLEPAIERARAIKDEYEVALIKKANRISALAHHSCLRAIKSAGNEREIEAVFTKECIANGAPKQAYSGIFGSGRSASTLHYVHNNQPLAGKLNLLLDAGAEYNNYASDITRTFPISGQFTKESREVYDIVLDMQKQCLAASKAGAVWDDIHILAHKVAIQGLLKIG...
Cofactor: Binds 2 manganese ions per subunit. Function: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. Catalytic Activity: Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Sequence Mass (Da): 50793 Sequence Le...
C4JY72
MSGVAEPDCYLTYDITSDTLTLYVPDFDLRRAIWMGPTLGLAEARERYNIDQAKYRSTLEQDILDWASRRAIGSVIYVIHDNQKPVVPFPYLKFNHEDLIPAMDTCREIKDGHEIGLIRRANEISTSAHTEILRNISGMRNEAEIQGKFLDSCVSLGAKNQSYEIIAASGENAAVLHYTRNDEPLKGRQLVCLDAGAEWNCYASDVTRTFPMQPRWPSAEAFSVYSVVQRMQEECIKRISEGVRYLDLHILAHKIAIEELLRLGIFRGGSIAEILKSGASLVFFPHGLGHHVGLEVHDVSGRSLMALEEQEYQGLPLRGC...
Cofactor: Binds 2 manganese ions per subunit. Function: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. Catalytic Activity: Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Sequence Mass (Da): 46144 Sequence Le...
Q9AR04
MSLTEEKPIRPIANFPPSIWGDQFLIYEKQVEQGVEQIVNDLKKEVRQLLKEALDIPMKHANLLKLIDEIQRLGIPYHFEREIDHALQCIYETYGDNWNGDRSSLWFRLMRKQGYYVTCDVFNNYKDKNGAFKQSLANDVEGLLELYEATSMRVPGEIILEDALGFTRSRLSIMTKDAFSTNPALFTEIQRALKQPLWKRLPRIEAAQYIPFYQQQDSHNKTLLKLAKLEFNLLQSLHKEELSHVCKWWKAFDIKKNAPCLRDRIVECYFWGLGSGYEPQYSRARVFFTKAVAVITLIDDTYDAYGTYEELKIFTEAVER...
Cofactor: Binds 3 Mg(2+) or Mn(2+) ions per subunit. Function: Involved in the biosynthesis of the antimalarial endoperoxide artemisinin . Catalyzes the formation of both olefinic and oxygenated sesquiterpenes, with amorpha-4,11-diene being the major product . Catalytic Activity: (2E,6E)-farnesyl diphosphate = (+)-amor...
Q46632
MKDISFSVVIPAYNASESIITTLDCLNEQSYKNFDVIIVDDKSADAQKLAEVVSSERYSGLKINLVLSETKLNGAGARNRGIDLATGDYVCFLDADDEWHKDKLQQNLSLIERLEGQGDRRFIIYSQVNIIQDGSFLKVMPLKPVGEHESIAEYLFGCYGFIQTSTIVLKREDAAEIRFDERYIRHQDYDLCIRADKLGFKFVMIAQPLANYHMVTRFGSQHKGESVKYSLFWLDAMKPHLTRRDVYTYKAYKLPLRYKMDGKSLQASLSFARYFFLTNKDNRNDFLKRLMNKLRTRLTGK
Function: Involved in the biosynthesis of amylovoran, which functions as a virulence factor. May function as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. Sequence Mass (Da): 34788 Sequence Length: 301 Pathway: Glycan metabolism; exopolysaccharide bi...
Q46633
MAIYWIVSYSILVFCFFELAMINQASEAKTKILINYFFLIGVFALILFAGIRGPDSGMDDSQYVGFFHDFSRQTGMTGYQAVANIYRYENFFMVLAWVASCFTHESYFFLLFISFIAVSTNAWVYKKYSPLILCSLCLYSAHLFINKDMNQIRFGLCSAFAIAFICSLVARNYLLALLFIVLSTQSHSTGYTIVMIIPFFFIRERKYLPLVLVIASIPLGIIGGKKLFLDSLGIVPVLGERAASYSGTNFDTTSPVFGLANLKNIAFIGAFTLYYFRKGIMKEDRFVYILLIAYSIGAAVRITFSDFSIFGGRVGNLFLH...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 42570 Sequence Length: 375 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. Subcellular Location: Cell membrane
Q46634
MYKLLILIDGISNSGGTDRVASTLSSLLSNHNYDVTLYSLNSGEPYYPVDNKVSIRQPKSSMRLFKLFEFIRYAKNTRPDGVMIISMGKLSVQALLLSKLFRVKSRLICCDHVSIETFSAAVRKLKVFCYGLAEKVVVLTQHDKNYLTSAFSLKNVYVVGNISPFHHENSLNRFDDVFARKQNRVLAVGRLTYQKNFGRLLDIWKNVHKQGWKLLIVGDGEEKAELLEKIKKYHLEESAEIVSPSKKISEYYRSSGVIAMTSRYEGLPMVLIEAKNYALPAIAFDCKTGPAEIIKDDGYVVDYQSNELFTAQLNQLIASE...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. May be involved in the formation of galactose alpha-1,6 linkages in amylovoran. Sequence Mass (Da): 39872 Sequence Length: 351 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. EC: 2.4.-.-
Q46635
MFSVLISLYNKEKPENLEQCLESLHQQTLNADEIVLVYDGPVSESLKAVATRWANLLPLVIVPLEKNLGLGKALNAGLERCTHNVVARMDTDDICLPERFEKQISYMESHPEVVLSGAAVIEFDEHGKERLKRLPLSNNDIHQFARMKNPFNHMCVVFRKDKVISAGSYQHHLYMEDYNLWLRIMSLGHPVANLPDVLMKVRAGSDMVNKRRGWNYIKSEVQLYRLKLALKQTGFIRGTLYFLIRTMTRLMPVKVMQFLYEKDRKG
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. Sequence Mass (Da): 30747 Sequence Length: 266 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. EC: 2.4.-.-
Q46636
MKRRELIRTAFSTIVATAALSSVSARARSEDLHGLTLKKVPPDAIPKNDVPIFSPDDVFTMPEQFWRDFKGKLYIGKAGTDPTLPQNLIDVFVKNANGGTALLSQPIDLNSETLKTFVAAKGALWSASEYSMALHNDNDEQIFYVPDVKNNGVSEFSRRLSQPGGYQLIGEISSFASLRQTRPLFSGAKVRLKGWHDGTEVGGGAFVGEMTPSEDDGGYIASSGQDFHWRRVSDDMNRITLFDFGAVADGKKDCLPAVMAMYHWAQNNNQKLSIQFPAGRFFISSFDISAKYIRFLRLAGAPVNFGYFPATTLVSDGKSE...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. May be involved in the polymerization or late modification of the repeating units. Sequence Mass (Da): 82253 Sequence Length: 743 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. Subcellular Location: Periplasm
Q46628
MREIEFTFKGLLIRLSLALSDLIFFNIALALAIVLINGFPGEILTGIPQHELDLKIATHILLSVICVGWFWVRLRHYTYRKPFWFELKEVFRTILIFSIVDLSVSALSKWELSRWIWILTWLLSMAMVPFGRACVKRLLNRKKLWKKQSIIIGSGKNAQEAWQALQSEEMMGFDVIAFYDVDGSQTALELFGVPVLKEEQQLWSLVDSDTQFIVAVEYEQSQSRDRWLKNLATHNCRSVSVIPSLRGVPLYGTDMAYIFSHEVMILRVSNNLAKHSSRFLKRTFDLVGALSIITLLLPALVILIFMVSRDGGAPIYGHER...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. May act as a sugar transferase and may be involved in the export of the repeating unit by flipping the lipid carrier to the periplasmic face of the inner membrane. Location Topology: Multi-pass membrane protein Sequence Mass (Da...
Q8VYB5
MGSSFETIDIATSARRIGVDNRISLKFYFRIADNILKQANIFRAEKNVIDLYVMLLRFSSLALETIPSHRDYRTSLKSNKEYLRMRLLDVLTELEKLKPVVQQRIDELYPKLKPRYNVQAHPANGSLGWSSAVKPSFNSYDHAKVRNPPGHNSGYMGSRGQQFLNAAPLEERFRKMSVNFRPNEETLSKHSILGPGGLSAQWQPPKYDTKVQYPSNIDFSPVVIPSFQQLVDSKPMITNGSNDEPEKPIVEPSVASNEKIQKNYTEELSSMISFEEPESVNENNLIRQPSPPPVLAEVQDLVPALCPEVREPECMIENSL...
Cofactor: Binds 2 Zn(2+) ions per subunit. Function: Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Location Topology: Peripheral membrane protein Sequence Mass (Da): 57383 Sequence Length: 507 Domain: The JAMM motif is essential for the protease activity. Subcellular Location: Me...
Q6NKP9
MVTLSSPSPSLSCVENVTCKSSHVSRVLISGTDNINHGESSEAKILRDVHISERLLEDFTELARENTEKDLETCGTLAAFLERGIFYVTTLIIPKQESTSNSCQAMNEVEVFSIQNERELYPVGWIHTHPSQGCFMSSVDLHTHYSYQVMVPEAFAIVVAPTDSSKSYGIFKLTDPGGMEVLRGCSETGFHPHKEPEDGNPVYEHCSNVYKNSNLRFEIFDLR
Cofactor: Binds 2 Zn(2+) ions per subunit. Function: Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Sequence Mass (Da): 24939 Sequence Length: 223 Domain: The JAMM motif is essential for the protease activity. EC: 3.4.19.-
Q5PNU3
MKIDLNKVAREIEVDNRIPLRNYYRIADNLLRQASIYREEKNVVDLYIMLLRYSSLISETIPFHRDYQASLPQERLGSRKRLRAVINELESLKPEFNQLVDKLNRVEDESRQDGSDLPVVSYSSDAVEWPPAHKASYSRPDINKPLPTSQPSWTYNNNLTSSSNRTQIDQQFQKLSFDFLPPNQATLSRHSFLGPNGLKRQMVAPKSEIKVQYPSNTDWGSADNSGLIEAGPSSSSASLNGDSQEVSTLNSVLSLDDGRWQRHSEAVNSQFISDATEDPFQFVGMKQPSPPPVLAQVHQELAQICPSKVADPRPGPAIPS...
Cofactor: Binds 2 Zn(2+) ions per subunit. Function: Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, but is not implicated in protein degradation by the 26S proteasome, deneddylation, or desumoylation. Required for intracellular trafficking (e.g. trafficking from the Golgi to the v...
Q46630
MINSILVVCIGNICRSPTGERLLKAALPERKIASAGLKAMVGGSADETASIVANEHGVSLQDHVAQQLTADMCRDSDLILVMEKKHIDLVCRINPSVRGKTMLFGHWINQQEIADPYKKSRDAFEAVYGVLENAAQKWVNALSR
Function: May function as a phosphatase required for amylovoran (an exopolysaccharide that functions as a virulence factor) production. Catalytic Activity: H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate Sequence Mass (Da): 15772 Sequence Length: 144 EC: 3.1.3.48
Q46637
MKILLVGNHTCGNRGDGAILRGIIDSLHLERTDLDIDIISRFPTSSSYLLQQNILPDELFLETKKSNSLVAKVKRRLMPKIMMAHIRGSGFFKNLAVPEYLQQFTDKLKQYDAVIQVGGSFFVDLYGPLQFEHSLCALLAKKPVYMIGHSVGPFQKERFNQIANFVFSRVNSLVLRESVSLEMMEKAGITTQKVIPGADTAFLVRTRTLDAPGHNLIHWQNQIAASKTIAITVRELAPFDKRLGVTQQEYEMAFGKVINAMIERGYQVVALSTCTGIDSYHRDDRMVAITLGDYVQQKDKYRVVMDEFNDLELGILLAGC...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. Sequence Mass (Da): 46292 Sequence Length: 415 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. EC: 2.-.-.-
Q46639
MSSYIVHRQNITRKEQSTIYWVNVLLSMLTGLLLVAIAWPISWFYHLPQLGGLIMLTSLNFLVLGSLSQYQAHFIKAKRMILLAKIEMVTKFLAFAFTVILLYYSPLGVSAVILGLFANAALRIGCMIWFGDKSWRPTFEFDQGTFYSSLKYGIYQLGSQTINQLRTQADSLIVGKVMGAELLGVYSLAKELILQPLKLVTPVINRLALPRFAEKQHDPVRLQQLFLKGTFVIMLFSAIMYLAIGILSPVIVRVLYGPAHEAVGQLIPLMLLFGMLRPMGGLTGAISQANGRTNVEFYWNVVASIIVVLVLASVWIWPQV...
Function: Involved in the biosynthesis of amylovoran which functions as a virulence factor. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 43726 Sequence Length: 388 Pathway: Glycan metabolism; exopolysaccharide biosynthesis. Subcellular Location: Cell membrane
C9K7C1
MYCDKGASSLANGLLPNVSGDITAKDNILDALDSSAEEHFWGRYIDGFEGQIFPQIPVSVHEAHLTGRARYEIILGNSMVTTLYTVSSIIRTGWALLVSQYTESQDVVIVSSLELPSQAMGGTILFPIRFRIRQDGRTEELLQSAKKHADKVLSSQKHDFPHTKDFVDPFSNSILLICTESQPSHSLEELLTELSASKKCALVLRCELLEDKISISAMFDPQVVRPRQTRRILDQLGHILKQISGSDMLVGDLDFLSPEDRQEIGRWNSRSALSDECIHALISKQAQQNPAAMAVNAHDGNFTYGELESYATRLAAHLIH...
Function: Nonribosomal peptide synthetase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (Probable). AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), de...
P37730
MAKKAKFFKNGIWYWLFIAPTLLSLIIVVLIPFIIGIYYSFTDWNGINQPVFIGLKNFMTLRDDAEFWNSIIFTAKFAVACIVIINVVGLSLAMLVTRKIFARNFMRTAFYLPNLIGGLILGFIWNFIFVDVFQTISDATHIGWLGGWLSTTNTGFWGLVIVTSWQMIGYVMVIYIAYIESIPTDLIEASKIDGANSWQQFRNVVFPLIAPAFTVSLFITLSNSFKLFDQNLSLTAGAPGNTTQMITLNIYQTAFSAQEMAVGQAKAVIMFLIIAVISVIQVYLTQKREVEM
Function: Probably part of a binding-protein-dependent transport system starch degradation products. Probably responsible for the translocation of the substrate across the membrane. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 32908 Sequence Length: 292 Subcellular Location: Cell membrane
Q03045
MRLLPSSCAGALSLLCSLAIAAPTELKARDLSSFIASERAIALQGALNNIGPDGSAVPGAGAGFVVASPSKANPDYFYTWSRDSALTLKMIIDEFILGNTTLQTIIEQYIHAQAVLQTVSNPSGTFLPDGVGLGEPKFMVDGTRFNGPWGRPQRDGPALRAIALMTYSNWLIKNGQFAEAKTKIWPIIANDLSYVGQYWNQSGFDLWEETYASSFFTIQNQHRALVEGAQLAHDLGVTCTGCDQAPEVLCFLQSFWNGKYIVSNINVNNGRTGLDGNSILGAISTFDIDAYCDSPTLQPCHSQSLANFKVLTDTFRNLYT...
Catalytic Activity: Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. Sequence Mass (Da): 66432 Sequence Length: 616 Subcellular Location: Secreted EC: 3.2.1.3
O74254
MKLLSKVFVTALGLTSIVNAAPTSSSSAEEAQKTVPVELSIGVKQLPNIHNDSAVDANAVAKGYSLVNVSLTARGLTGILKLKEATNIYGYDFEYLNLSVEYQSDTRLNVHIEPTDLTDVFVLPEELVVKPKLEGDAKTFNFENSDLVFEYDEEDFGFEVLRSSTREVLFSTKGNPLVFSNQFIQFNTTLPKGHSITGLGESIHGSLNEPGVVKTLYANDIADPIDGNIYGVHPVYYDQRYNTNTTHAVYWRTSAIQEVVVGETSLTWRALSGVIDLYFFSGPDPKDVIQQYVSEIGLPAMQPYWALGYHQCRWGYDTVE...
PTM: The N-terminus is blocked. Location Topology: Peripheral membrane protein Catalytic Activity: Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. Sequence Mass (Da): 105717 Sequence Length: 946 Subcellular Location: Secrete...
P29761
MSRKLIKYLPLLVLASSVLSGCSNNVSSIKIDRFNNISAVNGPGEEDTWASAQKQGVGTANNYVSKVWFTLANGAISEVYYPTIDTADVKEIKFIVTDGKSFVSDETKDTISKVEKFTDKSLGYKLVNTDKKGRYRITKEIFTDVKRNSLIMKAKFEALEGSIHDYKLYLAYDPHIKNQGSYNEGYVIKANNNEMLMAKRDNVYTALSSNIGWKGYSIGYYKVNDIMTDLDENKQMTKHYDSARGNIIEGAEIDLKKNSQFEIVLSFGNSEDEAVKASIETLSENYDSLKSAYIDEWEKYCNSLNNFNGKANSLYYNSMM...
Function: CGA has typical kinetic properties for a glucoamylase, but this bacterial enzyme had higher isomaltose-hydrolyzing activity than other eukaryotic glucoamylases. Catalytic Activity: Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of b...
D8Q9M3
MGLASTVSLALLGLCSLARAQTSAADAYVSAESPIAQAGILANIGPSGSKSHGAASGVIIASPSTSNPDYLYTWTRDAALVSRALVDEFIEGESSLQSVIDSYVSSQQKLQRVDNPSGSYTSGGLGEPKFNIDLTAFTGAWGRPQRDGPALRAITLITYGNHLLSSGNTSYVTDTIWPVVKADLDYVVSYWNQTGFDLWEEVSSSSFFTTAEQHTALRLGATFATAVGASASTYLTQADNVLCFLQSYWNSNGGYATANTGGGRSGIDANTVLTSIHTFDIEAGCDSVTFQPCSDRALSNLKVYVDSFRGLYSINPTGAT...
Catalytic Activity: Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. Sequence Mass (Da): 60941 Sequence Length: 576 Subcellular Location: Secreted EC: 3.2.1.3
A1DN11
MTVTISFEPYVGSSVDALSIPLYLRCQLVFKLSKPLAAVPLLESGVNRLVQALPFLSGEFTAVPASDGGKEILLVRPVLNFELSRILKIKYHETSLRHVCKQMNRPSSQGGDLPHEPYMPYPRLPDPSRPQPIVGFQVNVHTDGIILSVATHHCSFDATGMGSIVQNLAACCRSPPSDEPDLTTSPAQEAEARKVLSQVRETPFDPKMFPEYRPLDSMLSYYKGVQSALQGRQTTIVNRCFTIAADKINALKRRCNQLIPEMVKKYGLSTEDAIGSAWVSSNDVVAALLWTCINRARYPEIRERSVHQLPPDLLHATSSL...
Function: O-acetyltransferase; part of the gene cluster that mediates the biosynthesis of the prenylated pyrroloindoline diketopiperazine acetylaszonalenin . The first step in the pathway is the formation of (R)-benzodiazepinedione by condensation of tryptophan and anthranilic acid catalyzed by the non-ribosomal peptid...
P54802
MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPVLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTDHIYGADTFNEMQPP...
Function: Involved in the degradation of heparan sulfate. Catalytic Activity: Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Sequence Mass (Da): 82266 Sequence Length: 743 Subcellular Location: Lysosome EC: 3.2.1.50
P80884
MTSKVQLVFLFLFLCVMWASPSAASCDEPSDPMMKQFEEWMAEYGRVYKDNDEKMLRFQIFKNNVNHIETFNNRNGNSYTLGINQFTDMTNNEFVAQYTGLSLPLNIKREPVVSFDDVDISSVPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAVSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCGTRLNHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLARDVSS...
Function: Cysteine protease . Displays a high level of diversity in substrate specificity at the P1-P1' cleavage site . A hydrophilic P1 residue is preferred, with Gln or Arg strongly preferred . Favors an Ile/Leu residue at the P2 position of substrates, with an overall higher preference for Leu . The optimal tripepti...
A1DN10
MSPLSMQTDSVQGTAENKSLETNGTSNDQQLPWKVLGKSLGLPTIEQEQYWLNTAPYFNNLLIQCGYDVHQQYQYLAFYHRHVLPVLGPFIRSSAEANYISGFSAEGYPMELSVNYQASKATVRLGCEPVGEFAGTSQDPMNQFMTREVLGRLSRLDPTFDLRLFDYFDSQFSLTTSEANLAASKLIKQRRQSKVIAFDLKDGAIIPKAYFFLKGKSLASGIPVQDVAFNAIESIAPKQIESPLRVLRTFVTKLFSKPTVTSDVFILAVDCIVPEKSRIKLYVADSQLSLATLREFWTLGGSVTDSATMKGLEIAEELWR...
Function: Indole diterpene prenyltransferase; part of the gene cluster that mediates the biosynthesis of the prenylated pyrroloindoline diketopiperazine acetylaszonalenin . The first step in the pathway is the formation of (R)-benzodiazepinedione by condensation of tryptophan and anthranilic acid catalyzed by the non-r...
Q96K21
MNYDSQQPPLPPLPYAGCRRASGFPALGRGGTVPVGVWGGAGQGREGRSWGEGPRGPGLGRRDLSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQDQMIAERLARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPAHHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWSLEEEKSRLLAEAALELREEN...
Function: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or ...
Q9DAZ9
MESRCYGCAVKFTLFKKEYGCKNCGRAFCNGCLSFSALVPRAGNTQQKVCKQCHTILTRGSSDNASKWSPPQNYKKRVAALEAKKKSSTSHSQSLTHKDQAIAERLARLRQENKPKSVPSQAEIEARLAALKDEVQGPIPSTQEMEDRLAALQGRVPPSHTVRPAHQAPDTRTQAQQTQDLLTQLTAEVAIDENCQPRASASLQNDLNKGAARSQRTNSQGQASQSLEEEKYKLLAEAAVELQEENTRQERILALAKRLAVLKGQDPSRVTLQDYHLPDSDEDEETAIQRVMQQLTEEAALDEASGFNIPEKPAPGSRAQ...
Function: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or ...
Q84BZ0
MSADPFVIVGAGHAARRTAEALRARDADAPIVMIGAERELPYDRPALSKDALLNDDGEQRAFVRDAAWYDAQRIALRLGTRVDAIEREAQRVRLDDGTTLPYAKLVLATGSRVRTFGGPIDAGVVAHYVRTVADARALRAQLVRGRRVAVLGGGFIGLEVAAAARQLGCNVTVIDPAARLLQRALPEVVGAYAHRLHDERGVGFQMATLPRAIRAAAGGGAIVETDRGDVHADVVVVGIGVLPNVELAQAAGLDVDNGIRVDAGCRTADRAIFAAGEVTMHFNPLLGRHVRIESWQVAENQPAVAAANLLGADDAYAELP...
Function: Part of the multicomponent anthranilate dioxygenase, that converts anthranilate to catechol. Probably transfers electrons from ferredoxin (AndAb) to NADH. Catalytic Activity: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADH + 2 oxidized [2Fe-2S]-[ferredoxin] Sequence Mass (Da): 42869 Sequence Length: 40...
Q9BQD7
MEQDDPVEALTELRERRLGALELLQAAAGSGLAAYAVWALLLQPGFRRVPLRLQVPYVGASARQVEHVLSLLRGRPGKTVDLGSGDGRIVLAAHRCGLRPAVGYELNPWLVALARLHAWRAGCAGSVCYRRKDLWKVSLRDCRNVSVFLAPSVLPLLEDKLRTELPAGARVVSGRFPLPTWQPVTAVGEGLDRVWAYDVPEGGQAGEAASSRIPIQAAPGPSSAPIPGGLISQAS
Function: Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration . Probably also trimethylates ANT1/SLC25A4 . Catalytic Activity: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(...
Q501J2
MDQDDPAEALTELREKRLGLLEIVQAAAGSGLAVYTIWALLLQPGFRRVPLRLQVPYVGASARQVENVLSLLRGRPGKMVDLGSGDGRIVLAAHQCGLRPAMGYELNPWLVGLARLHAWRAGCSASVCYHRKDLWKVSLRDCHNVSVFLAPSVLQLLEDKLQAELPVGARVVSGRFPLPTWQPVAVVGEGTDRVWAYDVHGSGPTVSSCGVPIKAIPESSSTLVPRAPV
Function: Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration. Probably also trimethylates ANT1/SLC25A4. Catalytic Activity: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)...
Q9GZV1
MAKAPSWAGVGALAYKAPEALWPAEAVMDGTMEDSEAVQRATALIEQRLAQEEENEKLRGDARQKLPMDLLVLEDEKHHGAQSAALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAASHEPPPEPEEITGPVDEETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTPTDLV...
Function: Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. PTM: Phosphorylation at Ser-99 by PKB/AKT2 in response to oxidative stress induces ...
Q9WV06
MEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRE...
Function: Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. PTM: Phosphorylation at Ser-68 by PKB/AKT2 in response to oxidative stress induces ...
Q96BM1
MPWDARRPGGGADGGPEASGAARSRAQKQCRKSSFAFYQAVRDLLPVWLLEDMRASEAFHWDERGRAAAYSPSEALLYALVHDHQAYAHYLLATFPRRALAPPSAGFRCCAAPGPHVALAVRYNRVGILRRILRTLRDFPAEERARVLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPGLRDGGGLTPLELLLRQLGRDAGATPSAAGAPASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPRWQRLLGEDKFQWLAGLAPPSLFARAMQVLVTAISPGRFPEALDELPLPPFLQPLDLTGKG
Function: Substrate receptor subunit of a cullin-RING superfamily E3 ligase complex (CUL5-based E3 ubiquitin ligase complex) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . Depending of the metabolic state of the cell, promotes the proteasomal degradation of IMPDH2, the rat...
C5BV64
MRVLGMISGTSHDGIDVAVVRFTLDAGGAQLRGVVEHATTVPYPTALRARVAGALPPAQVGMAEVCALDADLGHAFADAAAEAAAAPDVPEPPDLVCSHGQTMYHWVAEGSALGTLQLGSPAWIAERLGVPVVADVRIRDVTAGGQGAPLVPLLDELLLAGASGRTAVLNLGGIANVTVVGDGADPVAYDVGPANALIDAAVAAAGRGAYDADGALAAAGRVHAPLLDALLTEPYYARRPPKSTGKELFDPGYVDRVRRGAGGAAAADLSLEDLVSTLTELTARVVAQDVRRLDVARLVVSGGGVRNPVLLGALTAAVPG...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q7VUW3
MDSTTHGPRTHVPGRLFIGLMSGTSMDGADGVLVRLDGPRPEVLASASLPMPAALRDELFALNHAGANELERAALAANGLARLYARAVRQLLDQAGLQPGDVAAIGAHGQTVRHRPDLGYTLQLNAPALLAELAGIDVVADFRSRDVAAGGQGAPLVPPFHAALFAGGQARAVLNLGGIANVTLLEPGRPPRGFDTGPANVLLDAWCQRHTGQPYDADGRFAAQGQVLADLLEHLIASEPWFALAPPKSTGRDLFNLDWLLARLQAFDGPAPQPQDVQATLQRLTARTVANAIDASAAAPRDVLVCGGGARNPGLMRELA...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
A6X3N5
MQPIWAVGLMTGTVLDGNIDVALLKTDGETIAEFGAYALKPYPRWIRDLLEQAQAEARVWNFEGAEPAIFAEAEEALTRAQSAAVRELVEESGLSMADIGVVGFHGQTVLHRAPQAGRLGDTRQLGDGRLMSQLLATKVAYDFRTADIRAGGQGAPLAAVYHAALLRSADASGNTAILNLGGVGNITWWDGDDALVAFDTGPANAPINDFMKKRGLGEMDRDGALAAKGKVDEDRLAELLKHPYLIAPYPKSLDRFDFTEMMADGLNEENGAATLTAFTTSAVGKALDILPRRPKRLAVSGGGRRNPTMMHMLVERAEVE...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q46HU0
MRVLGLMSGTSADGIDAVLVDFTGDPSRPKWQILNTFSYEYPSSIREKIIQVGQGLKISSKDWLELAEEITELNAFAARTCDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLANLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGWRGVLNLGGIANLTIIPPKTGIDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFYLEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKLKQIRLIELLVAGGGSKNLFLMRQLQK...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q15RS7
MNKHIEQLYRSAKKRSRLIIGLMSGTSLDGLDVALCRIEGHGTDTQIELVAFCTVDYDDGYKQKIKSVFAKRQVDLQQVTLLNPWVGVLHGQMVNQCLEKWNIAATDIDAIASHGQTIYHCPLGQHGQSEFGNATLQIGDADHLAVTTGILTIGDFRQKHIAAGGEGAPLAVYGDYLFFTSKQENRILLNMGGIANLTFLPCSADASAVFSSDIGPGNTIMDAYVQRHFSPLHYDKDSAMASQGKVHLGLLDSLLEHAFFALDFPKTTGPEVFNLDYLSVAQAHSATRQLAHEDVLATLNLFSARTIANAINDAAIELEE...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q9I5Q5
MPRYLGLMSGTSLDGMDIVLIEQGDRTTLLASHYLPMPAGLREDILALCVPGPDEIARAAEVEQRWVALAAQGVRELLLQQQMSPDEVRAIGSHGQTIRHEPARHFTVQIGNPALLAELTGIDVVADFRRRDVAAGGQGAPLVPAFHQALFGDDDTSRAVLNIGGFSNVSLLSPGKPVRGFDCGPGNVLMDAWIHHQRGEHFDRDGAWAASGQVNHALLASLLADEFFAARGPKSTGRERFNLPWLQEHLARHPALPAADIQATLLELSARSISESLLDAQPDCEEVLVCGGGAFNTALMKRLAMLMPEARVASTDEYGI...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P (By similarity). Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus ...
Q3K5W7
MALYIGVMSGTSLDGLDIALIEQSSAINLVATHYIPMPDTLRAELLGLCAGGPDEIARSAIAQQNWVKLAAQGIHTLLEQQQLKPEAIRAIGSHGQTIRHEPARGFTVQIGNPALLTELTGITVVSDFRSRDVAAGGQGAPLVPAFHEALFEERTGNRAVLNVGGFSNLSLIEPNKPVAGFDCGPGNVLMDAWIHQQRGENYDRNGQWAASGKVEPTLLKALLSDPFFVTQGPKSTGREVFNLPWLEQQLSCLPGFAAENVQATLLELTALTIVESLQSAQSNTEELLVCGGGAHNVTLMKRLADLLPNAKVASTATHGV...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q88QQ4
MALYLGVMSGTSLDGLDIALVEQGEQLELLATHYLPMPPDLRQDLLALCSSGPDEIARAALAENRWASLAGEGIRQLLARQGLKPEAVRAIGSHGQTIRHEPARGFTVQIGNPALLAELTGISVVADFRRRDVAAGGQGAPLVPAFHETLFSQLGRRLAILNVGGFSNLSLIEQDKPVHGFDCGPGNVLLDAWIEREHGHPYDADGAWAASGVAQPGLLSALMADPFFAGSGPKSTGREVFNLPWLDRHLANLPAYRAQDVQATLLELTARSIIDSLGKAQQGTEALLVCGGGARNGALMARLGQLLPAARVASTGAYGV...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P (By similarity). Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus ...
Q3ICY1
MHPHISKLYNSALKPSRLIIGLMSGTSLDGLDVALCKITAAGVHTQIEVLKFTTVDYSDDYKTKIKQVFAKRECNLEYLTLLHPWVGKFHGDMVNQCLNSWQVNPANIDVIASHGQTIYHCPKSQHQYNDFNNGTLQIGDSDQIAVTTGITTIGDFRQKHIAAGGEGAPLAVYGDYLFFSSSDENRILLNMGGIANLTFLPQNGDSNAVFSSDIGPCNTIMDAYVQRYFNNMHYDENAAIAKAGFINTALLTALCDNHFLTLKMPKTTGPEVFNLAYLEAAQQASNTQKLSHQDVMATLNRFTAEVIANALNTCVKMAPN...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q4FQ90
MDDLNYATLTEALEQTVFENFDDGLYIGMMSGTSLDGMDAILCQFSNHTNSSNISNEDNTQQPMHLLATYSQDFPPRLREVLLALCQPNGINQLTPTAGEPDSELEWFGWASKAYAEFASDVVNTLLQQSNTDIESVLAIGCHGQTVRHRPQMGFSLQLVDANIIAERTGISVVSDFRRRDMAVGGQGAPLVPAFHQALFAVPDSTRILLNLGGIANIAVLPAISDDLSDFNEHSDNQPSDSVVGYDTGPANLLLDAWTALHTDKDYDAGGTWAQSGQVVEPLLNQLLEHPFFVKAYPKSTGREDFNLAWLQDELQKFDQ...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q8Y241
MTTLASSISERYIGLMSGTSLDGVDGVLVDFSGPRPMLLTDAYVPFPPALRQAFFDLQSAGHNEIHREALAANALADLYAECVAQLLHESGCDPREVRAIGAHGQTIRHQPGEHDGIGYTRQTQHAAVLAERTGIDVIADFRSRDIAAGGQGAPLVPAVHRALFALPDAWRVVCNIGGIANLTVLPPQQSDARDRVLGFDCGPGNALLDYWVHAHRGEAYDRNGEWARSGWIDAALLETLRSEPFFARMPPKSTGRDLFNPTWLQQQAGDTLERIRPEDVQATLLALTADTIADAVRTHAPRTASLVVCGGGARNGALMQ...
Function: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in ...
Q6P6B7
MAQPGDPRRLCRLVQEGRLRALKEELQAAGGCPGPAGDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHL...
Function: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of S...
A2AS55
MALPGDPRRLCRLVQEGRLRDLQEELAVARGCRGPAGDTLLHCAARHGRQDILAYLVEAWSMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLDVIQDLVEHGANPLLKNKDGWNSFHIASREGHPVILRYLLTVCPDAWKTESNIRRTPLHTAAMHGCLEAVQVLLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLEQHKACSSAADSMGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALHYAAKEGQTNTVQTLLSLGADINSTDERNRSVLHLACAGQHV...
Function: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity . Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of ...
Q499M5
MAPPGDPRRLCRLVQEGQLRALREELEVAGGCWDPEMFRGSQGPAGDTLLHFASRHGRQDILAYLVEAWSMDIEAANRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLEVIQDLVEHGANPLLKNKDGWNSFHIASREGDPVILRYLLTVCPDVWKTESKIRRTPLHTAAMHGCFEAVQELLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLENHEACSSATDSLGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALLYAAKEGQTSTVQTLLSLGADINSTDERNRSAL...
Function: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of S...
Q945B4
MGSCSPQLPLICLSDQTLKPGSSKWVKVRSDVRKALEDYGCFEAKIDQVSMELQGSVLKAMQELFALPTEAKQRNVCPKPFAGYFSHNGLSESFGIKDANILEKAHEFTQQLWPEGNKSIKMIQLYAEKLAELDMMVRRLILESYGIEYFIDEHLNSTYYRMRLMKYIARPDNDITAAVGANVDNGANDNADGDANVNDDGASIGVKVNVDVGDDVNDNDSVNIGVGVDINVETNVNGDLDAEANGDATAWVVGAVSGNASVGAKEANVDAELGLPSHTDKSLSGIIYQHQIDGLEVKTKEGKWIRVKPAPNTVIVIAGD...
Cofactor: Binds 1 Fe(2+) ion per subunit. Function: 2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis. Catalyzes the conversion of methylsulfinylalkyl glucosinolates to hydroxyalkyl glucosinolates. Sequence Mass (Da): 44943 Sequence Length: 410 EC: 1.14.11.-
Q8NK92
MRPLSHLSFFNGLLLGLSALSAATSVVHERREATSSNWVKRARVNPSDKHVVRIGLTQSSLEEAHDLLMDVSNPSSPNYARFYSADEVAAKFAPSTETVNEVQNWLTEKGINASRVAQTQNHGWLVFHATSKEIENLFDTTYYEYHNRKTGKKAIACEQYHVPASVQKHIDYVHPGVNLNPSSGKPSSIRRRAAASKKTKLPARGPRPIQQHDVKGLNVTNCDQLITPECIRALYKIPSARAAPHPNNSLGIFEEGDYYAQEDLDLFFKTFAKDIPQGTHPIPAFIDGAEAPVPVTKAGGESDLDFELAYPIVHPQSITL...
Cofactor: Binds 1 Ca(2+) ion per subunit. Function: Serine endopeptidase which hydrolyzes a range of fluorogenic peptide substrates containing the basic residues arginine or lysine at the P1 position and prefers paired basic resides. Also hydrolyzes clupeine and salmine, activates plasminogen and converts trypsinogen t...
Q9ZUC1
MNAALATTTATTPVLRRETPLLHYCSLTTKSPVYQINRVRFGSCVQTVSKKFLKISASSQSASAAVNVTADASIPKEMKAWVYSDYGGVDVLKLESNIVVPEIKEDQVLIKVVAAALNPVDAKRRQGKFKATDSPLPTVPGYDVAGVVVKVGSAVKDLKEGDEVYANVSEKALEGPKQFGSLAEYTAVEEKLLALKPKNIDFAQAAGLPLAIETADEGLVRTEFSAGKSILVLNGAGGVGSLVIQLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDLPDKYDVVFDAIGMCDKAVKVIKEGGKVVALTGA...
Function: Reduces the double bond in short-chain unsaturated carbonyls . Acts preferentially on alpha,beta-unsaturated ketones rather on alpha,beta-unsaturated aldehydes . Has no activity with (E)-2-hexenal and (E)-2-pentenal . Contributes to detoxify stromal reactive carbonyls produced under oxidative stress . Sequenc...
Q9V035
MFGYWGKILRVNLTDGTIKEETFNEEFAKKWLGTRGFGIYFLLKEMDPKVDPFSPENKLIFATGPLTGTSAPTGGRYMVITKSPLTGYIAMANSGGYFGAELKFAGWDAIIIEGKADHPVYLYIHDENVEIRDASKVWGKLVSETEKALKEEVGDKHVQIASIGPAGENKVRFAAVMNNGHRAAGRGGVGAVMGSKNLKAIVVRGHKRVEVADKGKFMEVIREKIEKLKKDPVAGGGLPKYGTAVLVNIINEHGLYPTRNFQTGVFEYAYEQSGEAMAAKYLIRNKPCFACPIGCGRVNYLPSIGETEGPEYESTWALGA...
Cofactor: Binds 1 [4Fe-4S] cluster per subunit. Catalytic Activity: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] Sequence Mass (Da): 67520 Sequence Length: 607 EC: 1.2.7.5
Q51739
MYGNWGRFIRVNLSTGDIKVEEYDEELAKKWLGSRGLAIYLLLKEMDPTVDPLSPENKLIIAAGPLTGTSAPTGGRYNVVTKSPLTGFITMANSGGYFGAELKFAGYDAIVVEGKAEKPVYIYIKDEHIEIRDASHIWGKKVSETEATIRKEVGSEKVKIASIGPAGENLVKFAAIMNDGHRAAGRGGVGAVMGSKNLKAIAVEGSKTVPIADKQKFMLVVREKVNKLRNDPVAGGGLPKYGTAVLVNIINENGLYPVKNFQTGVYPYAYEQSGEAMAAKYLVRNKPCYACPIGCGRVNRLPTVGETEGPEYESVWALGA...
Cofactor: Binds 1 [4Fe-4S] cluster per subunit. Function: Catalyzes the oxidation of aldehydes to their corresponding carboxylic acids. May have a pyroglycolytic (saccharolytic) role. Catalytic Activity: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] Sequ...
Q8GZP5
MANTKDSYHIITMDTKESSIPSLPMKEIPGDYGVPFFGAIKDRYDFHYNQGADEFFRSRMKKYDSTVFRTNVPPGPFNARNSKVVVLVDAVSYPILFDNSQVDKENYFEGTFMSSPSFNGGYKVCGFLGTSDPKHTTLKGLFLSTLTRLHDKFIPIFTTSITSMFTSLEKELSEKGTSYFNPIGDNLSFEFLFRLFCEGKNPIDTSVGPNGPKIVDKWVFLQLAPLISLGLKFVPNFLEDLVLHTFPLPYILVKRDHQKLYNAFYNSMKDILDEAEKLGVKRDEACHNFVFLAGFNSYGGLKVFFPSLIKWIGTSGPSLH...
Function: Cytochrome P450 metabolizing both 13- and 9-hydroperoxides of linoleic and linolenic acids, but with a marked preference for 9-hydroperoxy fatty acids . Has no activity toward 13S-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13-HPOT) . Catalyzes not only the synthesis of allene oxide, but also its hydr...
Q3SYW1
MSASAVFILDVKGKPLISRNYKGDVAMSEIDHFMPLLMQREEEGALTPLLSHGRVHFLWIKYSNLYLVATTLKNANASLVYSFLYKIVEVFSEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQGNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGSIKLKVFLSGMPELRLGLNDRVLFELTGRSKNKSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDA...
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. PT...
P35602
MATSAMFILDLKGKTIISRNYRGDIDMTAIDKFIHLLMEKEEEGSAAPVLTYQDTNFVFIKHTNIYLVSACRSNVNVTMILSFLYKCVEVFSEYFKDVEEESVRDNFVVIYELLDEMMDFGFPQTTESRILQEYITQEGQKLISAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNMLASANGTVLQSEIVGSVKMRVYLTGMPELRLGLNDKVLFEGSGRGKSKSVELEDVKFHQCVRLSRFDTDRTISFIPPDGAFELMSYRLTTVVKPLIWIETSIERHSHSRVSFIIKAKSQFKRRSTANNVEIIIPVPSDAD...
Function: Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development a...
P47795
MIHSLFLMNGGGAVFLEKHWRSVVSRSVCAYLLEAQLKAGQPENVAPVLATPHHYLVSTHRHGISFVAVIQAEVPPLFVIEFLHRVAETLQDYFGECSEASIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDQLPTGQLSNIPWRRVGVKYTNNEAYFDVTEEIDAIIDKSGSTVFAEIQGVIDACIKLTGMPDLTLSFLNPRLLDDVSFHPCVRFKRWESERVLSFIPPVGNFRLMSYHVNSQNLVAIPVYVKHNINFRDDGSTGWFDITIGPKQTMGKVVENILVIIHMPKVVLN...
Function: Component of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP47 is a subunit of the plasma membrane adapter. PTM: Regulated...
Q8LEZ8
MIHFVLLVSRQGKVRLTKWYSPYTQKERSKVIRELSGVILNRGPKLCNFIEWRGYKVVYKRYASLYFCMCIDEADNELEVLEIIHHYVEILDRYFGSVCELDLIFNFHKAYYILDELLIAGELQESSKKTVARIISAQDQLVEVAKEEASSISNIIAQATK
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE). The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo mole...
P61966
MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane ...
P56377
MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane ...
Q96PC3
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDMLQEVSTVSQTMGER
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane ...
O94669
MSTIEAIYLVDTNGALLLQLESRGRTSPITLEHIKNELFRYKLRNEEPPFILHNKNFLIFQELEEDVRLCIPTTCDTEPLYIHDIMRRIVDVVKTFFGGFNASKVEKNVCVIVQLLAEMIDYGYATCMEPNALQDIVPLPSFMNKFMAVTGLQTNTPTLARDTVPWRTAKAKYATNEFFIHVLERVSAVYQPNGKLAFGTVKSDMECKCQISGMPLLLLSLRPGTKLGNVRFHQSVNLKRWKQHPDQIEFIPPDGKFTLASFQTDFATQKSLPVVVEAKNKLDGRFEVRIRNTGKKSVENLKILITIPQALKSVTVTEGN...
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity...
P38153
MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLEDSSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDLLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCVEINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSI...
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. Required for ...
Q92572
MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with...
Q1JQA3
MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEMPRNINIGDLNIKVPNLSQFV
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with...
P59780
MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with...
Q8VZ37
MIKAVMMMNTQGKPRLAKFYDYLPVEKQQELIRGVFSVLCSRPENVSNFLEIESLFGPDSRLVYKHYATLYFVLVFDGSENELAMLDLIQVLVETLDKCFSNVCELDIVFNYSKMHAVLDEIVFGGQVLETSSAEVMKAVEEISKLEAASNSISLVPKSVSGWRGR
Function: Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also ...