ids stringlengths 6 10 | seqs stringlengths 11 1.02k | texts stringlengths 108 11.1k |
|---|---|---|
Q9PBZ3 | MNTPTHTHPHPFGSTATIRCERAAAELRTGRPVLLIDAHTRRHAVMALDSMTAQSFTTFANAVGNTHYLFLTPARSNVLGLEAPQGARIPLATLSYDSLVKLAYLRQPTHPTTWVPGDIMDAAATEITRLALLLPAIVAAPLTHHTEHAFADCQTLDLTDLDTAAAGASTTEYELVTRTPVPLRDLGMSEFIVFRGGIAQRDQVAILIGQPDLSSAVPVRVHSSCLTGDLFGSLKCDCGDQLRHGLATLKALGGGVLLYLDQEGRGNGIAAKIRAYGYQHVGLDTIDADAQLGFGPDERRYTGAVMMLRALGITRIQLLS... | Cofactor: Binds 1 zinc ion per subunit.
Function: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Catalytic Activity: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate
Sequence Mass (... |
Q8ZEF0 | MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHLALIFGDISGDKPVLSRVHSECLTGDALFSLRCDCGFQLEVALTRIAEEGRGVLIYHRQEGRNIGLLNKIRAYALQDLGADTVEANHQLGFAADERDFTLCSDMYKLLGIKAVRLLTNNPKKVEILTQAGINIVERVPLIVGENPKNEHYLATKAAKMGHLLTK | Cofactor: Binds 1 zinc ion per subunit.
Function: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Catalytic Activity: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate
Sequence Mass (... |
O66679 | MSEREEFKFNTVEEAIEDIRQGKMVIVVDDPDRENEGDLVMAAEKVTPEAINFMAKYGRGLICLSLTPERCEQLDLHPMTPMNTDPKGTYFCVSIDAHPKHGTTTGISAYDRALTIKLAISPDAKPSDFVRPGHVFPLKARPGGVLERAGHTEASVDLARLAGLYPAGVICEIMKDDGTMARVPDLMEFAKKHNLKIITIADLIKYRLRRETLVEKVASAHLPTPWGVFKIHAYRHKLTGEEQVALTMGEWKEDEPVLVRVHSECLTGDVFRSFRCDCRPQLEKALEMIAKEGKGVLVYILGHEGRGIGIANKIKAYELQ... | Cofactor: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
Function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Catalytic Activity: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)
Sequence Mass (Da): 45577
Sequ... |
Q8EKF2 | MNQSLLAPFGTAIERVEAGLNALRQGLGVLVVDDEDRENEGDLIFAAESLTNAQMAMLIRECSGIVCLCLPDEKVKALALPPMVENNSSQYGTAFTVSIEAKVGVTTGVSAADRVTTIKTAIADHAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDLMQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLANVG | Cofactor: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
Function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Catalytic Activity: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)
Sequence Mass (Da): 22956
Sequ... |
A8GYS3 | MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIRECSGIVCLCLTDERIKQLQLPPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKAAIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDLMKLAGLQPFGVLCEVTLPDGTMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ | Cofactor: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
Function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Catalytic Activity: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)
Sequence Mass (Da): 23015
Sequ... |
Q979C2 | MIRVMATGVFDILHLGHIHYLKESKKLGDELVVVVARDSTARNNGKIPIFDENSRLALISELKVVDRAILGHEGDMMKTVIEVKPDIITLGYDQKFDEAELQSKINKLGITVKIVRISKYDGQLNSSSSVRKKIMELIGERY | Function: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
Catalytic Activity: ATP + FMN + H(+) = diphosphate + FAD
Sequence Mass (Da): 16009
Sequence Length: 142
Pathway: Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/... |
K4REQ6 | MNWLNSEAFVLFDQHIIWSDMVGNILGLITLALGFRRSLWTWPVQFLSGLVLFGAFYGHLTGSAGKQAVVMAVALYGWYQWNRGTDKAADGKVSVRFATWAERGAMIAAAAVGTVAVALLFKAYPSLSWDPWPDAYIFVGTIVAMYAQARGMVEFWFAWLLVDLVGVPLNFANGYAFSGFVYVIYGALVLWGMRDWWLRSRRDSRPVLEGAPA | Function: Transports riboflavin and roseoflavin . Can also transport FMN and FAD . May confer roseoflavin resistance to S.davawensis, which naturally produces this antibiotic during stationary growth phase .
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 23749
Sequence Length: 213
Subcellular Locati... |
A6WUW2 | MVAACSAYAAVNVATQWAGTRTGIPSVIIAFWQYVIALVLTLPLLVRDGTRALRTSHFGLHVMRVALAAAGVQVWIYALTHVPIWQVVALSMTSPFFVILCARLFLQEKVTPARLLTTFTGFIGALIIIAPWSDSYTVYSLLPILAAALWAGYSVMTKYLTRFEKPASISAYMLVLLTPINAALWLASGLSMSAITAPDVEIWSILIVIGAFTALAQYFQTAAYSIADAVYLQPFDDLRLPINVIFGWIVFAAAPSINFWPGAALIIGASLYLMRQDSGTSRTA | Function: Transports riboflavin into the cell.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 30844
Sequence Length: 284
Subcellular Location: Cell membrane
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Q1MIM3 | MKDMNQTSLAVEPSRAVVGALWMVLAGIAFSLLNVVTQWLTMKLAFPSASAAFWQYGFAFLFSLPFLKRLGLAAMRTHYPWRHLTRVVLAALGVEAWVAGLAAVPIWQAIALVMTSPFFIILGARLFLGERVGPARWAATAAGFTGAMIILQPWSDGIGWAALLPVLSALLWGASSLITKSLTGIERPETITVWLLVLLTPINGGLALAAGFAVPTGATLALFLLAGLLTAVAQYFLTLAYAAADAAYVQPFDDLKLPLNVLAGWLFFGYAPAGYLWLGAALILSASLFIMRNEMRRERKPA | Function: Transports riboflavin into the cell. Can also transport FMN and FAD. Required for normal nodule development during colonization of pea plant roots.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 32511
Sequence Length: 302
Subcellular Location: Cell membrane
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Q9KKU0 | MSIKHHPLQGALWMLTAGLAFAIVNSVAQYASIQFGLPSTTVALVQYAIAIVVILPYLKTLGIRQSLRTQQFGWHLLRVFLAVIGIQLWLWALAYPVPIWQGIALLMTSPLFATIGSGLWLREKVGMARWVATLTGFIGAMIILEPWADDFNLASLLPVGAAFFWASYSLMVKKLSSHDSPSTMVVYLLLLITPFNLLLALPDWQMPNGQTVWLLLIGAGVMTALAQWAIAKAYAVADASFVQPFDHAKLPLNVLAGWLVFGWVPPGRLWLGAAIIVLSVAFITQWETKKSRRERNIA | Function: Transports riboflavin into the cell.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 32891
Sequence Length: 298
Subcellular Location: Cell membrane
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Q9STY4 | MALSFRISSSSPLICRATLSNGDNSRNYHTTDAAFIRRAADLSEMSAGLTSPHPNFGCVIATSSGKVAGEGYLYAQGTKPAEALAVEAAGEFSRGATAYLNMEPGDCHGDHTAVSALVQAGIERVVVGIRHPLQHLRGSAIRELRSHGIEVNVLGEDFESKVLEDARKSCLLVNAPLIHRACSRVPFSVLKYAMTLDGKIAASSGHAAWISSKLSRTRVFELRGGSDAVIVGGNTVRQDDPRLTARHGQGHTPTRIVMTQSLDLPEKANLWDVSEVSTIVVTQRGARKSFQKLLASKGVEVVEFDMLNPREVMEYFHLRG... | Function: Pyrimidine reductase involved in the riboflavin biosynthesis pathway. Has also a non-functional N-terminal deaminase domain that lacks the catalytically essential zinc-binding residues.
Catalytic Activity: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+)... |
P94465 | MTIIAGTVVKGKQLGRKLGFPTANVDAKIHGLRNGVYGVLATVNHQFHLGVMNIGVKPTVGSNLEKTLEIFLFDFHRDIYGEKIECSILFKIREERRFDSLESLTKQIKKDISCVAKRFELIGIMAPNKKESLLSHQELNLPDLCFYKKCNNLYGVNRGVYNVIDNWFFEYGITQVAYRRIYILSFLSFLKEDNPKVSSKYIRFGAGGLADKLNRFISSYVEESEENILG | Function: May be directly involved in the regulation of the rib genes. C-terminal part of RibR specifically binds to RFN of the rib leader of the riboflavin biosynthetic operon. The RFN element is a sequence within the rib-leader mRNA reported to serve as a receptor for an FMN-dependent riboswitch. Possibly, RibR produ... |
P0CI36 | MSKTRRMVLIAMLAALSTILLLPILQFPLLPGIDFMKVELSIIPVLIGVFTLGLGDGFIILFIRSVLWYLLFNQGPSTWIGVPMNFVALGIFMAIVWFFTKKKFSIKNYTVGIVLATIASVLVMMVLNVFYALPLYRLAAGFDVDKIFAGATHLFNMGSLSVTLNPTYLLTVVLPFNALQYIIFALVFGLIVTVFKKNKVVKFYNA | Function: Mediates riboflavin uptake, may also transport FMN and roseoflavin (By similarity). Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of di... |
Q03WN0 | MSIIPVTRVQRTTLIAILSAISFGLMLFPQVPIIPSADFLKLDFSIVPVVIGLYWLNYSASLWVILIRTLLKLILANEGVNTYLGLPVNLLVVLAFITVLKITMPNLEQYSNWQKKILPLISSTFVMTIVAIVINWFVAIPLYARFANFDIAKFIGLKNYFIGMVLPFNLIEGIIWFVVSMIILRAIQPLQRRFHS | Function: Probable riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracyt... |
Q8Y5W0 | MKNYSMKVFVSVAVLGTLAFILMMLQFPLLPSAPFLKLDFSDIPALIGGLLFGPLAVILVELIKNVLLYIVSGSPVGVPVGELANFISGLFYVLPIYYLFHWLRSTKGMVLSTAVGTVLMTGAMAVFNYFVLLPFYIKLGGLPANTDVAWLITYAIVPFNLLKGVIVSAVFLLLYSRLKKWIAKNQTMKERRKFEKRQQEISH | Function: Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex (By similarity). Mediates uptake of riboflavin . Can also transport roseoflavin (RoF), and probably 8-demethyl-8-aminoriboflavin (AF), toxic riboflavin analogs . In addition, during intracellular growth, binds and impor... |
E5QVT2 | MNGRRKLNMQQNKRLITISMLSAIAFVLTFIKFPIPFLPPYLTLDFSDVPSLLATFTFGPVAGIIVALVKNLLNYLFSMGDPVGPFANFLAGASFLLTAYAIYKNKRSTKSLITGLIIATIVMTIVLSILNYFVLLPLYGMIFNLADIANNLKVIIVSGIIPFNIIKGIVISIVFILLYRRLANFLKRI | Function: Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrat... |
Q5M614 | MRSLFFGIGKSIGNFFQIVKIWRNFFMTNTRKLAYIAILSAVSFLLLYFSFPLIPAADFLKVDFSILPVLIALVIFDFKSAIGVLLLRSLLKLLLNNGGPGSMIGLPMNFVALGVFVWGLSYFWKKNQTSKNYILGSVLGTILLTVAMVVLNYIYAVPLYAKFANFDIAQFIGLYKYLFAMVVPFNLLEGLIFSVAFALIYAPLKSILVKL | Function: Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex. Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters th... |
Q9X1G6 | MSSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSILKLETVEGRSNNG | Function: Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex. Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters th... |
Q6F0N9 | MDKKYKLWNYKYDFSEINLKNWKEVLKDTFKLNTRKIALLSMLFAIEILMTIISKVIMGLAIPMIVGVYTIEISFFVILIIYLCSNYIYASILSITAIWFRLLLGSEPVGLLSMMISDTAFLTIFAVLFFILKKFIFLKFKFKNQIKILIALICFAGLISMIGSGFISMLCNDKFIFEMYYLSDDGSGYWKMLLWVGFGVTLAKYSINILLFASTLKVLLILIKQSRV | Function: Probably transports riboflavin.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 26329
Sequence Length: 228
Subcellular Location: Cell membrane
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Q7MGG3 | MHFVSYSLCYDVRSNIMEQPIYFYEPDENHGFLANFYPCSITVSGTCWPSSEHYYQAQKFDDVRLQEKVLRAEDAAQAFRLSREYQQWQRHDWYDIRVEVMRFIVREKFLQNTPLAHQLLATGDTELKEHSHKDAFWGDGGDGHGRNELGRILMMVREELQEHAPYNLVQFIDSAKLPTQWGTFQMYGFIEKATGKEHLALVYGDIEQQAAPLIRLHSECLTGDALFSARCDCGFQLAKALQNIVAEGAGVLLYLRQEGRGIGLINKIRAYHLQDDGADTVEANEQLGFGADMRDYAFCRGILSFLGIERVRLMTNNPRK... | Cofactor: Binds 1 zinc ion per subunit.
Function: Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless produ... |
Q8A947 | MIKNIVFDFGGVIVDIDRDKAVQAFIKLGLADADTRLDKYHQTGIFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNEVDLRKLDYILGLRKSYHVYLLSNTNPFVMSWACSPEFSSEGKPLNDYCDKLYLSYQLGHTKPAPEIFDFMIKDSHVIPSETLFVDDGSSNIHIGKELGFETFQPENGADWRQELTVILNS | Function: Catalyzes the dephosphorylation of D-ribitol-5-phosphate and D-ribitol-1-phosphate. Is also able to dephosphorylate 5-amino-6-(5-phospho-D-ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway.
Catalytic Activity: D-ribitol 1-phosphate + H2O = phosphate + ribitol
Sequence Mass... |
A9WGD1 | MQQTLPVTRVSPRVRSLQRFEWPALGLPVTLMLLLVFWQAGVTLSGYPAFILPSPALVAGRFWQALSSGLLWQHTLATLSAALGGFTLALIIALILGYTLAHIRWLEQALAPVLAASQAIPVVAVAPLIILWFGAGLTSKVLVAALITFLPILINTVVAIRSIPRELIEMAYISGANRWQLLRYVEAPLALPVLFGGVRTGLALATTGAVVGEFVAGRVGLGALINIARGLFDTPLIFVALATLALITLTLYVLAGLLERLLVRWEAS | Function: Part of an ABC transporter complex that transports riboflavin into the cell.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 28685
Sequence Length: 268
Subcellular Location: Cell membrane
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P38615 | MNIQSNNSPNLSNNIVSKQVYYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSP... | Function: Serine/threonine protein kinase that is thought to function in regulating kinetochore activity and entry into meiosis. Could phosphorylate IME1.
Catalytic Activity: ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
Sequence Mass (Da): 43005
Sequence Length: 370
EC: 2.7.11.1
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Q9VQ37 | MAQNTADTLIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQRRKLSTTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNLVGVAPSRAIYFCTYSQTKNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYNSKVQMTVRQCIERVYAQGGVAAFYKGITASYFGICETMVHFVIYEFIKSKLLEQRNQRHTDTKGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREEGNKYNSFWQTLHTVWKEEGRA... | Function: Mitochondrial transporter that imports purine and pyrimidine nucleotides into the mitochondria. Essential for maintaining mitochondrial structure and function. Appears to be important for mitochondrial gene transcription and mitochondrial respiration.
Location Topology: Multi-pass membrane protein
Sequence Ma... |
O67156 | MMEEYVVIGKVLDTFGLEGELKVRPYAPPEVFENLEKVYLKRKGGDWVPFEVEWVDFIDDKVIIKFKGYDSIDEVEQFKGAKLFLPKEELPELGEEEYYAYELVGMEVETDKGKKLGKVERVQDMGPYDALVLDKENLLVPFVSDIVLKVDKENKKIIVKEELLPV | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A0JXU0 | MQLQVARIGKPHGIRGEVTVQVLTDAPEDRFIPGTRFVVEPASAGPLTVDSARWNKDILLLGFEGIETRNQAEALRGAKLFIETEELEEEDDEGWYEHELVGLDVRVGDAVVGTISGLRTLPVQDLIVVESPDGKEILIPFVEEIVPEVNVGEKYILVTPPPGLFEINVEDSGETSDAGESGPGEAEPGKAEAGDNA | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A8IKV0 | MTDRILIARIGAPHGVKGEVRLFAFGEDPLALKRYPLTDESGARRFKVQSLRAAKDHFVARLEGIADRNAAEALTNTDLFVPRDALPAAEDEDTFYHADLMGLRVEDQSGALLGTVLAMHDFGAGDVLEYTPEGGGRTLLLPFTKAAVPVVDVPGGRIVVVPDTNPDETPPEDADQA | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
B6YRA4 | MINFNELIKVGNFNKSHGIKGEISFVFTNNFFFKGKNSFLICEMEGIFIPFRVESYRSISNSTVLVKLKNINTIEQTKLLTYQEVFLPKKQSAENTKLNYFSWDHYIGFNIIDEKNREIGSITDIDKSTINTLFIVEKESKEILIPTANEMIVTIDEKRKIIYMKLPVGLL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A1K9L0 | MMVLGRIVAPFGVQGWLKIHPFGDDPAAWRKMTHWWLAEDPDGPESAWVQYKLASCRPHGKGLVALLEGVPDRNAAEAIEGRYVGAPRDAMPAPEKDEYYWGDLVGLDVVNETDETLGRVSGLISTGAHDVLQVEDGETERLIPFVAAYVLDVDLAARRIRVAWQKDW | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A0RHL5 | MTKWFNVGKIVNTHGVKGEIRVVSRTDFPEERYKVGNTLYISNEKGGEPFPVKITSHRQHKTFDLLTFEGYGNVNEVEQFKGSLLKVPEDQLGELAEGEYYYHEIIGCNVVTEEGEALGTIKEVLSPGANDVWVIKRPKGQDLLIPYIDDVVLQVNIENKLVTIHVMEGLL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A7GRH2 | MTKWFNVGKIVNTHGVRGEVRVISRTDFPEERYKVGNTLYIWGEKGTEPLPVKVTSHRQHKTFDLLTFEGYSNVNEVEKFKGSLLKVPEEQLGELAEGEYYYHEVIGCKVVTENGEELGTITEILSPGANDVWVIKRPKGQDLLIPYIDDIVLQVNVEQKQVTIHVMEGLL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q2J6Z8 | MAEEIVVGRIGRPHGIRGEVTIEIRTDVPHRRFVVGAVLGREGGGTALTVSGAHWHSGRLLLHFRGVDDRGAAEALRGVLLTIDADQAGSPLDDADGDGEAVEMWWDRDLVGLRAVTTAGMLLGHVTDIIHSPAGDLLAIGGPDGGEHLVPFVRDIVPTVDPPAGRIVVDPPPGLLDLD | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
B0TX17 | MSQDFVEIAKIGATYKLDGELNLYPLASSIETLLSYGDWYIQLPANSAWQPLKDESVLRRADKLYIKLASVNDVETAKKYVNSLIGVPKEALPKVGNDEAYFTDLIGCTIVNTANDSFGKVIGIIETGANEVLVCKKDSDEYLIPYVKQYIVSEDLDLKKIVVDWEYDY | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A8L5A4 | MGEPVVVGRVGRPHGIRGDVTVDVRTDLPERRFAPGARLVRQVADGPASRPAADAAGAADAVGTAAGPGSAGDSGAARAAGPPVATVLSVVASRWHSGRLLVRFDGVTDRDAAEALRGSFLTIDSDECGPAVDPDDEDDDGELWWDRDLVGLHARTPAGDVLGEVVDVIHSPGGEILAIGRPEGGEYLVPFVREIVPTVDPAAGHIVVDPPPGLLDLD | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q8RGK8 | MELLIAGKVLGSHNLKGEVKVISDLDNIEVLVGNKVILELADSQQKLLTIKKIEHLVANKWIFSFEEIKNKQDTIEIRNANIKVRRDIVGIGEDEYLVSDMIGFKVYDVKGDEYLGEITEIMDTAAHDIYVIESEEFETMIPDVDVFIKNIDFENRKMLVDTIEGMKESKVKK | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q74FG4 | MRQDDLKLLGKIVTTHGIRGQLKVASFSGEFDTILSLETVVLKGKDGRMETFPVARATVHHDRVLLSLTPFTNINEVLHLISAVSYAHRDQFPPLEEGEYYWCDLIGLQVVTAAGTVIGRLDSILPTESHDVYVVRGADREYLIPAVEDVVVQVDLEAGTMTVSPPEGLLDL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A9BD47 | MSRKDSWLTIGKLVGAQGLRGEVKVNPSSDFPERFINPGERWLQKNTEEPSRIELKSGRQLPGKSIYIVSFIGITDRNKAESIVGNKLLVPSDQKPKLKEGEFHLVDLLGLKAKFTQDGSDVGEVIDLTSAGNDLLVIKLVEGKTVLIPFVKEIVPVINLKQGWLLIKPPPGLLEL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A2BYY9 | MINHDEWLIVGLITSPQGINGKIKVKSLSDFEERFTKPGIRWIQKETESPKKLQLISGFQKPGKESFVITFKEIKNRNEAEKLKGYKLLVKVDEIPKLNKNEFHLTELMNLKVKILENNKLKIIGKVVNLENEKNNLLVIKLLTNDKEVLVPFVKEIIPEIDIKNKFLIITPPPGLLEL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q7V9R4 | MCKKIIWLTIGKIVAPQGLSGKVRINPSSDFPERFIKSGDRWLQYDNEEPQKIQLNSGRQIPGKSIYVVEFQGIDDREKAKALVGKKLLIDSSHRPTLAPGEFHLLDLLGLKVRLKNDHREIGEVTNLTSAGNDLLEVRLLSGKKVLVPFVKEIVPEIKLQEGWLMVCPPPGLFDL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q7V4K0 | MNGDEDWLTVGKVVAAQGMQGELRINPSSDFPERFTLPGQRWLKERNGEPRPIELLTGRQLPGRSLYVVKFAGVNNRNAAEALVGQKLLVPSSDRPSLAEGEFHLLDLVGLEARLQAEGPAIGHVIDLTTAGNDLLEIELLTGRRVLVPFVEAIVPEVQLNQGWLRLTPPPGLLEL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q46IK7 | MFEKDKWMTIGEIVAPQGLRGDLRIKPSSDFPERFTKPGKRWIQKTDELPTEIKLTKGKLIPGKSIYVLSIEGVSTRSSAEEIIGWKLVIPIDSRPMLSKDEYHYHDLIGLEARRGPSKALIGYVTDLIKGGNDLLEIELVEGKKVLVPFVKEIVPEIEIKEKWLLINPPPGLLEL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q9HXQ0 | MPTPADDLVVIGKIVSVYGIRGEVKVYSFTDPLDNLLDYRRWTLRRDGEIRQAELVRGRLHGKVLAAKLKGLDDREEARTFTGYEICIPRSELPSLEEGEYYWHQLEGLKVIDQGRQLLGVIDHLLETGANDVMVVKPCAGSLDDRERLLPYTGQCVLSIDLAAGEMRVDWDADF | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A8F3G2 | MSDYVVIGKITKTHGLFGSVKVLPLTNALEVFQKLENVFIKNDAQSNTHRLQIEEIRKAGKGFLIKFSGIDDEERARKIVGLSLAVRVTDLPKPKSPNEYYYYELLNVEVLDQSGNFIGRVEDIIQTGSNEVAVVKNGSFEMLIPVIHDYIIKFEKRKRLVVKVPEWI | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
B2V7T6 | MKKDLIAIGKIHGTHGVKGNLKFEIFVKNFYLPEEIYIKDEENELQPLNIETVDRKKGLIKFKNYDTPEKAKEISHRLIYVPEDLLPKLGEDEFYEFQLIGMDVYYNDKLIGKVEKIDDRLSQAYLIIKCTDEKTRHLPFINEFVKDVNVKENKMQITPPEGWFSL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q67PD9 | MAGQSRPDLIRIGQVTAPHGVRGAVRVYPTTDFPERFVTLKRVMIDGPDRAVGARFRGFVKNLVILELEGITDRNQAERLRGADLLVPREEVHPLPEGYYYDFDIIGIEVVDPDGRQLGRVVEVDHTSPVHDLYVVETAPGKRYLVPAVRRFVKEIDLETGRMVIDPIPGLLED | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q2LVU6 | MKFFEIGEIVKSHGLKGRMKAKSYVENGEDLSSVHEAMIVKGKEEPRGYKVRKIVLHKTYFFLELETIDTVESADSLVGSTVLIPEDDRAALSGDEYYWRDLMGLQVVTEEGRFLGRIESIFPTGSNDVYVCAGGSREILLPAISDVILKIDLDKKEMVVRLLPGL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q3A2E6 | MVLQQSDLLILGVVIGTHGLRGDLKIRGSDQDFPLLSKMHQLVFLREGETVLKCARRKAGWYKGHLLLQIAGYRDVRAVQHLVGCEVAVRRDDVPGLPAGEYYWFQLKGMTAVDRRLGALGCLEDIFTTAAHDIYVINGDYGEVLVPAVKAFIADVDLESNRILFDLPDGLVQET | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
A0LMM1 | MSKTVEPACLVPVGKVTRTHGIRGALKIFPYGESLAAQAAGERFFLRSKNGGYCTLTLIGLRAQGRMLVCGFEEIKDVNGAQPFVGEEIFLPEDRLPPVSEGEYYHYRLIGLDIVTLDGESLGVLRKIIETGGNDVYVAEREGREILIPAIEDVIREIDLERKRMVVDLPEGLVDA | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q2JUD0 | MVASRDTAWLLVGQVVAAHGLRGWLRVKCWSDFPERLTEPGPRWLQRDSDPEPLLHPLIEGQFFPAKGLYLVRLEGIPDRTAAEAWVGAKVLVPASQRLPLEPEEYHYSDLIGLAVYHQGRLLGHVSAIWAAGQDVLEIATPDKRQVLIPFVKALVPVVDLEKGELQVQPPPGLVESFLGQDRARN | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
B1XKY8 | MAEQDWIIIGQVVAAQGLKGEVRINPSTDFPERFEVPGQRWLQLPNQDPQSVELERGRQIPGKNLFVVKFEHIQDRTQAENIRGAKVLVRAGDRPELEADEYHVSDLIGLEVFDYNTQAKLGIVSDLYTAAQDVLEVTDANQKKHLVPFVKAIVPVVDLVENRLEVDAPPGLFEI | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q0IDP0 | MTSTPSPSTADPNSTNDWLPVGTLVGAQGLKGELRLNPASDFPERFTEPGTRWLQAKGSAPKEVELLEGRQLPGKSLYVVRLKGVNNRASAEALVGCTVLVPAKDRPELAEGEFHLLDLVGLEARLAGSDEPIGTVSNLISGGNDLLEIKLNSGKTVLVPFVEAIVPDVQLEEGWLLLTPPPGLLEL | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q0AWV6 | MNSDKLVAIGKIAGTYGYAGWLKVIPLTDFPERFYKLDKVILNQGGKLGTFLVDGLKAHNNFYLFKFSGIDTVEVAQGFQNGILQIDESELYPLPEGYFYHFQLQGLSVYDEEKGLLGELTDIIETGANDVYVVDSPQYGEILIPAIKDVILAVKLEEKRMEIKLLPGLIED | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
P74035 | MAEPMTEQQKTENWLEIGTIVAAQGIQGEVRVLSASDFPARFLTKGQRWIRKTPQETPQPLTLKKGKQIPGKNLYILRFTEITDRNQAEALVNYQLLVPATDRLPLEPGEFHVTDLLGLIVYDHDNGDRLGIVTDFYSAGNDLLGITLDKNPDKEVLVPFVEAIVPTVELAEQRLEIKTIPGLLD | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
B7IEQ6 | MINTLRELLSGKVAVAILGKTHGLKGELKLHPFTNFPEIIESLEEIFLYNEKTKQFMVATVENLRLADGYYIIKLNGVENVENARKFVGSKVYINKDELPNLSKDEYYFFEIVGSQVIDESGKVLGVVDEVIQTGSNDVIVVNKNKEDEILIPVIYDYIITLDKENKKIVVKVPEWLD | Function: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but ... |
Q97I40 | MDKLKFGLVSLGCDKNRVDSEIILGSMNRDYEIVNDPREADVILVNTCGFIESAKQESINTILEMNKYKEKYNCKMLIATGCLTQRYGKELKELVPEIDAILGVNDYKSLDDAIEDFFNLGKKDIYCNYSDQSINEGKRIITTGEYSSYVRISEGCNNSCSYCIIPKIRGKYRSRQFENIIDEVRELSENGTKEVILIAQDTTRYGVDLYGRKRLHELLKEMSLIQGIEWIRIMYCYPEEITEELIEEIASNEKVCNYIDMPIQHISDNILKNMFRKTRKSEILDKVEKIRKKVPNIAIRTSLIVGFPGETEGDFNELCD... | Cofactor: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Catalytic Activity: [sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen ... |
Q18BJ2 | MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIVNTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVGTGSYQNIDKILKELSEIHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCTYCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELLEELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRKTTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDF... | Cofactor: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Catalytic Activity: [sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen ... |
A5N854 | MDKLKVGLISLGCDKNRVDSEIILGNVKSAYEIVTDPKLADFIIINTCGFIESAKQESIDTILEMSQYKGKYNCRGIVVTGCLAQRYGIELMELLPEIDIMLGVNDYDKLVENINNFISDKQNKIHNCGYSDLNINEGKRILTTKSHTAYLRIAEGCDNYCTYCIIPKIRGKYRSRSIENILQECNELSLRGVKEVILIAQDTTRYGIDLYNKKMLPELMRSISKIEGIEWIRLLYCYPEEITEDIIDEIALNDKVCNYIDIPLQHISDNILKLMGRRGRKKDILRNINELRKKINDISIRTTIIVGFPGESEEDFKELK... | Cofactor: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Catalytic Activity: [sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen ... |
A1S2T9 | MNKTVETFDPKQTTTLETPAKTLAAEAKASDGTIQGNRIGFVSLGCPKNLVDSERILTQLRIDGYEVTNSYDNADLVIVNTCGFIDAAVEESLDAVREALEENGKVIVTGCLGAKENQIREVHPDVLEITGPHSYEAVLNHVHKYVPKPEHNPFTSLIPQTGVKLTPKHYAYLKISEGCDNRCTFCIIPALRGDLDSRGVGSVLDEAKRLVESGVQEILVVSQDTSAYGKDKDGRTDFWNGMPVKQDITSLARQLGKMGAWVRLHYVYPYPWVDDLIPLMAEGLILPYLDLPLQHASPRVLKMMKRPGRVDRQLDAIKKW... | Cofactor: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Catalytic Activity: [sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen ... |
A0QVH8 | MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWSTRRANRLGSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAMYKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGETGCVAPQITLEEMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAAAVRKLDGPTRIEFKRDGRVMDTVVDVTPTQRFTSADASAPSTVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKIGALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFW... | Function: A probable intramembrane site-2 protease (S2P) that cleaves type-2 transmembrane proteins within their membrane-spanning domains. Degrades PbpB (PBP3, FtsI) under conditions of oxidatives stress; degradation is inhibited by Wag31-PbpB interaction. Also cleaves anti-sigma factors RskA, RslA and RslM. Site-1 pr... |
P10297 | MKSMLVVTISIWLILAPTSTWAVNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYVGGSCQTTYNQNAMFPQLIMSTYYNYMVNLGDLFEGF | Function: Possesses antiviral potency. Inhibits viral infection of plants (tobacco mosaic virus) . Inhibits protein synthesis . Releases both adenine and guanine from Escherichia coli rRNA in vitro. Activity on guanine is 20 times slower than that on adenine .
Catalytic Activity: Endohydrolysis of the N-glycosidic bond... |
Q7M1L7 | VTSITLNLANPTAGQYSSFVDKIRNNVRDP | Function: Exhibits N-glycosylase activity . Catalyzes the release of one adenine from a ribosome . Acts as a ribosome-inactivating protein and inhibits protein synthesis in a rabbit-reticulocyte lysate system and in various cell lines (in vitro) .
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one speci... |
P98185 | VIIYELNLQGTTKAQYSTILKQLRDDIKDPNLXYGXXDYS | Function: Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 4625
Sequence Length: 40
EC: 3.2.2.22
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P56626 | MALSFFFLAISLGSPTAIGDVSFDLSTATKKSYSSFITQLRDALPTQGTVCGIPLLPSTASGSQWFRFFNLTNYNDETVTVAVNVTNVYIVAYRADAVSYFFEDTPAEAFKLIFAGTKTVKLPYSGNYDKLQSVVGKQRDMIELGIPALSSAITNMVYYDYQSTAAALLVLIQCTAEAARYKYIEQQVSSHISSNFYPNQAVISLENKWGALSKQIQIANRTGHGQFENPVELYNPDGTRFSVTNTSAGVVKGNIKLLLYYKASVGSEYDIPTTILHPGAMGMLHNQNGNYVTM | Function: Inhibits protein synthesis by depurinating 28S rRNA in ribosomes.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 32235
Sequence Length: 294
EC: 3.2.2.22
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P98184 | MRSIGFYSVLALYVGAHVTEDVDINFSLIGATGATYKTFIRNLRTKLTVGTPRVYDIPVLRNAAAGLARFQLVTLTNYNGESVTVALDVVNVYVVAYRAGNTAYFLADASTEANNVLFAGINHVRLPYGGNYDGLETAAGRISRENIELGFSEISSAIGNMFRHNPGTSVPRAFIVIIQTVSEAARFKYIEQRVSENVGTKFKPDPAFLSLQNAWGSLSEQIQIAQTRGGEFARPVELRTVSNTPTFVTNVNSPVVKGIALLLYFRVNVGTDNVFAMSLSTY | Function: Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 30754
Sequence Length: 282
EC: 3.2.2.22
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P24477 | AVKTITLNLVSPSANRYATFLTEIRDNVRXRSLDYSHSGIDVIGAPSSRDSXLNINFQSP | Function: Single-chain ribosome-inactivating protein.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 6602
Sequence Length: 60
EC: 3.2.2.22
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P04399 | AAKMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNEPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLEDAVTALHGRTKADKASGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVEKKSGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFTPIEKMGVRTAEQAAATLGILLFVEVPGGLTVAKALELFHASGGK | Function: Inhibits the elongation phase of protein synthesis. It inactivates fungal ribosomes even more effectively than mammalian ribosomes and is thought to function as a constitutive antifungal agent in plants.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Seq... |
A0QQH5 | MNIRPLRQSVRPSPIFLLVIAVTAAGGALAWIAADTIRPLSYVGVFILVIAGWLMSLCLHEFGHAFTAWRFGDHGVETRGYLTLNPLKYTHPMLSLGLPVLIIALGGIGFPGGAVYLQTHWMTARQKSIVSLAGPAANLVLAVLLLGLTRAFWDPAHAVFWSGIAFLGFLQVTALVLNLLPIPGLDGYGALEPHLNPETQRALAPAKQWGFLIVVVLLITPALNRWFFELVYWFFDFSGVSSYLVSAGGQLTRFWSAWF | Cofactor: Binds 1 zinc ion per subunit.
Location Topology: Multi-pass membrane protein
Sequence Mass (Da): 28371
Sequence Length: 259
Subcellular Location: Cell membrane
EC: 3.4.24.-
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D3ZUQ0 | MEEPLGSPPAALSALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRVERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLNHKDVGFSEEELQKHEGMSERERQVMKRLKEVVDKQRDEIRAKDRELVLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEEAEIPPQPDGEESISDAEKAALDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQ... | Function: Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the... |
P85101 | RPSWTVDSDSAKYSSFLDSLREEFGRGTPKVCNIPVTKKANNDKFVLVNLVLPFNRNTITLAFRASDAYLVGFQDRDSKTNKLRANFFSDEYRALSGKYKSIFTDAEVLAPALPCASTYTDLQNKAGVSREKLSLGVSSLQTAFTAVYGKVFTGKNVAKFALISIQMVAEAARFKYIEDQVINRGMYSSFEAGARITLLENNWSKISEQYHKSCKLGGGQFTEEEMKLGLLLYN | Function: Ribosome-inactivating protein of type 1, inhibits protein synthesis in animal cells. Inhibits cell-free translation in rabbit reticulocyte lysate system with an IC(50) of 0.17 nM.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 26132
S... |
P84073 | PRGSPRTEYEAARR | Function: Has antifungal activity against F.oxysporum and M.arachidicola. Inhibits cell-free translation in rabbit reticulocyte lysate system. Has some N-glycosidase activity.
Catalytic Activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Sequence Mass (Da): 1646
Sequence Length:... |
Q2WG80 | MNSVCFATPHTKHMDSKMQLTSSPASLWRPWLVTRKDAQTECRRTKLACPYSRPEVPGNTTTDGKMQSFQHPVRLYWPRSKSFDYLFSDGEALLRNFPVQATINFYDESDSEDEEESCDEDDESDVEDCLKHNSHFTAFN | Function: Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites.
Sequence Mass (Da): 16209
Sequence Length: 140
Domain: The... |
Q0D2K3 | MDSAACAAAATPVPALALALAPDLAQAPLALPGLLSPSCLLSSGQEVNGSERGTCLWRPWLSSTNDSPRQMRKLVDLAAGGATAAEVTKAESKFHHPVRLFWPKSRSFDYLYSAGEILLQNFPVQATINLYEDSDSEEEEEDEEQEDEEEK | Function: Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites (By similarity).
Sequence Mass (Da): 16379
Sequence Length:... |
Q2WG77 | MDPAASPAAAPPAAPAAAPAADPAADPAAALPGQALAQAPALAQINGQEGARNERAAYLWRPWLSSINDQPRQARSLVDWADNRATAAEAAKTDSDFHHPVRLYWPKSHSFDYLYSAGEILLNNFPVQATINLYEDSDSADNEEDKEEEEEEEEEEDDEEEEEDEDKDVNENEPEVCMGVSEATTHKATAHSPDPHSACPN | Function: Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites (By similarity).
Sequence Mass (Da): 21804
Sequence Length:... |
Q2WG79 | MENITFTSGLNSEMDANQPWRPWLSQTSRKAPDYKPYKRPADDEQHKLSIFKHPVKLFWPKSQCFDYLYEDAEVLLRNYPVQATICLYEDPDTEDEEDYSDEEDEKELR | Function: Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity).
Sequence Mass (Da): 13070
Sequence Length: 109
Domain: The ripply homology domain is required for transcriptional repression.
Subcellular Location: Nucleus
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Q5TAB7 | MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN | Function: Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity).
Sequence Mass (Da): 13906
Sequence Length: 128
Domain: The ripply homology domain is required for transcriptional repression.
Subcellular Location: Nucleus
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P69925 | MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAV... | Cofactor: Binds 2 iron ions per subunit.
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
Catalytic Activity: [thioredoxin]-disulfide + a 2'-deoxyribonucleosid... |
P28847 | MSIENSKEAALTAELSLAGAFFYTPECPDIEHLRSLSVANRWLDTDLPISDDLKDVAKLTPAEREFYRFLFAFLSAADDLVNLNLGDLSALFTQKDILHYYIEQESIEVTHSRVYSAIQLMLFGNDAAARARYVASIIGDAAIGRKVAWLQAKVRECGSVAEKYILMILIEGLFFASSFASIAYLRTHNLFVVTCQSNDLISRDEAIHTRASCCIYNNYLGGFEKPEPKRIYELFSEAVNIECEFLLSHAPQYSHLLDIGAIISYVRYSADRLLGEIGLSPLFNAPKPSPSFPLAFMTVEKHTNFFERRSTAYSGTLIND... | Function: Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Catalytic Act... |
Q8SRR2 | MSHGEETELLLDPKEERFVLLPIKYHDIWKMYKKAESSFWTVEEVSLDKDIDDWGKLNAKERHFISYVLAFFAASDGIVNLNLVERFSTEVKVLEARFFYGFQMAIENIHSEMYSLLIDTYIRDNDEKNFLFDAIRTIPSVKEKADWAIRWIEDKNSDFATRLVAFACVEGIFFSGAFASIFWLKKRGLMPGLTFSNELISRDEGLHCEFACLLHYHLKKKCNRIKEVVMDAVEIEKKFLSESLPVNLIGMNCNLMCRYIEFVADRLLENLGEERVYNATNPFDFMENISLVGKTNFFDKRESQYQKAFVGIENGNDSFR... | Cofactor: Binds 2 iron ions per subunit.
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Catalytic Activity: [thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-d... |
Q6GZQ8 | MFPHVTIVEKPGCGNCVTLKRALKEKSVPHTVMPYVPGVPGSYPIATVGGQRVGYREITKALAMDMFTTSKCFKPFRYNWAEDIRTKHEKVHWVETEINLRDDVTDWKSGVMTPGEKAFVSCVLRLFTQLDVEVGALYLDHLTQVFRCNEIRNMLTSFACREAIHQKAYSLLNDTLGMPDCEYQAFADYGEMTDKLDFMREMDCSTLPGLARSLLRAVLNEGVSLFAAFVMLLTFQRSGKMKGMGKVVEWSVRDENIHVEGVSKLFETLNSEYPWVVTKDLIELFKEDAERVAELEEAFVDLAFQECGPVCGLEPKQVKD... | Cofactor: Binds 2 iron ions per subunit.
Function: Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Catalytic Ac... |
Q9KFH7 | MEQLQKRKIYDTTASNASTGILNGKSSNVLNWDDVRFSWAYPLYKNMLANFWTPFEINMSHDAKQFPTLTETEQEAFKKIIGLLAFLDSVQTDYSMRAAEYLTDSSLAALMSVLSFQEVVHNQSYSYVLSSLVPKATQDEIFEYWKHDDVLKERNEFIIDGYEKFVDNPTPKTFLESIVYDVILEGLNFYSGFAFFYNLARNQKMVSTSTMINYINRDEQLHVYLFTNIFKELLVEFPELNTEETKTFVKTTLMKAADLEKDWFRYIIGDKIPGINPEDMETYISFIANKRAVQLGMEKPYPEIKHNPMKWIRAYEDVNS... | Cofactor: Binds 2 iron ions per subunit.
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Catalytic Activity: [thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-d... |
P55983 | MEVSRKKIYNPNSTESVNERKIFGGNPTSMFDLNKIKYQWADHLWKTMLANTWFAEEVSMNDDKRDYLKLSAEEKIGYDRALAQLIFMDSLQANNLIDNINPFITSPEINLCLVRQAYEEALHSHAYAVMVESISANTEEIYDMWRNDMQLKSKNDYIAQVYMELAKNPTEENILKALFANQILEGIYFYSGFSYFYTLARSGKMLGSAQMIRFIQRDEVTHLILFQNMINALRNERADLFTPQLINEVIGMFKKAVEIEALWGDYITQGKILGLTSSLIEQYIQFLADSRLSKVGIAKVYGVQHPIKWVESFSSFNEQR... | Cofactor: Binds 2 iron ions per subunit.
Function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
Catalytic Activity: [thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-d... |
P61720 | MGKIKVGVVTARWNQEITSKLEEGAISYLEACEDVEIFAALVPGAVEIPLACQAFLEAGCDGVVALGVVIRGDTSHYDYVCNSVTDGVTRLMLDYKKPIGFGVLTTENEEQALARAGGDHGNKGEEAAQVTMEMIGLTQEIPAAMKTALMLAKKAPAKAAKKPAKAAAKTQKKKKKVRK | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
B2ICH3 | MAEPRRALAQMDDARISVGNARFLIIEAPYYEDIAAQLRAGAEAALTRAQARFDVVSVPGALEIPIALAIALDRAPALYQGAIALGCIIRGETYHFEIVANESARALTQLVVERKLPFGNGILTVETETQALERASVESGDKGGDAARAALALYRFSQEFGQVVEQAQIQAQRPVLTSGAR | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q7VRI2 | MDVIEGNTVVSNITKIVVVVARFNKAINNHLLEGTIDTLKRVGQVQDENITIVWVPGAYELPLVSQALSISNKYDAIIVLGTIIRGITEHFEFIYKSCNFGLSNISISNLVPIGLGLLVTNDIGQAVERIGIKGNNKGSEAALAALEMINILKTIKNNN | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q494E6 | MNIIESDTIANKAKIAIAVVRFNRFVNNNLLEGALDVLKRIGHVKDENITIIWVPGSYELPLIAKALAISHKYDGIIALGTVIRGFTIHFEFVAKECSSGLSRISMENTLPIGFGLLTTDNISQAIERSGIKANNKGSEAALAVLEMINILKIIKNSS | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q7VTN4 | MNPYILTPDLNGEGLHIGIVRARFNEEIGQAQLQACLEELGKLGVDERDVMVVSVPGALELGVALARMAESYEFDALIALGAVIRGETYHFEVVSNESAAAISRIALETGIPVANGVLTVDTDEQAQARAAGKGADCAQVAVEMANLAAALEPEEDDEDDEDEDFDDEEDDGR | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q8K9A6 | MNIIQSGINVKNASITIIIARFNEFINKNLLSGAIDTLTRIGQIDKEKILTIYVPGTYEIPIVASYIANTNKYDAIIAIGTIIKGSTDHFKHIANDAYSNLSRISTKYFIPITMGILTTENIQQSIERSGTKMGNKGSEAALAALEMINIMKKLKKINN | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
C5D3M9 | MKVMEGNLVGTGLKIAIVISRFNEFITSKLLSGAMDGLKRHGVNENDVTVAWVPGAFEIPLIAKKLAESRQYDAVIALGAVIRGATSHYDYVCNEVAKGVSHAALSTGTPVIFGVLTTDTIEQAIERAGTKAGNKGWEAAVSAIEMANLLRTFA | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q7NLS9 | MTVFEGNLQDTRDLKFAIVIARFNDLVVGKLLSACEDSLRRHGVAVGPDSHQVDYAWVPGSFEIPMVARQLALSGRYDAIVCLGAVIRGQTSHYDHVASEVAKGIQALAFQTGVPVTFGVLTTDTMQQAIERAGIKSNLGWEYGENAIEMATLTRKIRHLVAVRAVQPELPEQTPPSLLQ | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
Q7VM44 | MAKITGNLVATGLKFSIVTARFNDFINDKLLSGAVDTLVRHGAVESDIDTVWVPGAFEIPLVAKKMAESGKYDAVICLGTVIRGSTTHYDYVCNEVAKGIGAVALQTGVPIMFGVLTTESIEQAIERAGTKAGNKGAECALGAIEMVNVLKAL | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
P45149 | MKVLEGSVAAPNAKVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYELPLVARRLAESKKFDAIVALGTVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALTALEMVNLIQQIDAA | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
B9LUV3 | MVSLGLVVARFNDSVTEPMAEAAREAATDRDAVIVDEVSVPGAYDSPLAADRLARRDDVDAVAVVGAIVTGDTDHDHVIASATADKLTQVSLDRDTPVTFGVSGPGMSGAEARERIDKGADAAEAAIDLADELD | Function: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Catalytic Activity: (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = ... |
O28856 | MKIGIADTTFSRINMGKIAIDELRKISSIPYERYTVPGIKDLPIAAKKLLEEKGCDIVITLGWVGGTQKDMLSYIVLSMGLVIVQLMTNKHVIDVTIHEDEAEDEKTLMMVAENRVREHVRNAVDLLVNPKRLQKLAGTGQRQGYPDVGPILK | Catalytic Activity: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin
Sequence Mass (Da): 17083
Sequence Length: 153
Pathway: Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.
EC: 2.5... |
Q9HB40 | MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRKDAYMFWWLYYATNSCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDSDLKPRKTTWLQAASLLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGGKMAAGIGLELYKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAEVSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFTQSHLVCLCQRHVRHLQRDALSQLMNGPIRKK... | Function: May be involved in vascular wall and kidney homeostasis.
Sequence Mass (Da): 50831
Sequence Length: 452
Subcellular Location: Secreted
EC: 3.4.16.-
|
Q58584 | MTKKVGIVDTTFARVDMASIAIKKLKELSPNIKIIRKTVPGIKDLPVACKKLLEEEGCDIVMALGMPGKAEKDKVCAHEASLGLMLAQLMTNKHIIEVFVHEDEAKDDKELDWLAKRRAEEHAENVYYLLFKPEYLTRMAGKGLRQGFEDAGPARE | Catalytic Activity: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin
Sequence Mass (Da): 17495
Sequence Length: 156
Pathway: Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.
EC: 2.5... |
Q59587 | MIKVGICDTTFARYDMGGAAIDEIKKHATGIKIIRRTVPGIKDLPVACKKLIEEEGCEMVMALGMPGPEEKDKVCAHEASTGLIQAQLMTNTHILEVFVHEDEEDDPEDLKVLADNRAREHAQNLIMMLFRPERLTRDAGMGMREGKPDVGPL | Function: The relatively low activity of this enzyme suggested that 6,7-dimethyl-8-ribityllumazine might not be its natural substrate.
Catalytic Activity: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin
Sequence Mass (Da): 16969
Sequence Length: 153
Pathway: Cofactor biosyn... |
Q920A5 | MELSRRICLVRLWLLLLSFLLGFSAGSAIDWREPEGKEVWDYVTVRKDAHMFWWLYYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTQLKPRNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISVELYKAVQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSMSLLDNQGLAEVSDIAEQVLDAVNKGFYKEATQLWGKAEMIIEKNTDGVNFYNILTKSSPEKAMESSLEFLRSPLVRLCQRHVRHLQGDALSQLMNGPIKKK... | Function: May be involved in vascular wall and kidney homeostasis.
Sequence Mass (Da): 50965
Sequence Length: 452
Subcellular Location: Secreted
EC: 3.4.16.-
|
Q920A6 | MELSRRICLVRLWLLLLSFLLGFSAGSALNWREQEGKEVWDYVTVREDARMFWWLYYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTRLKPRNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISLELHKAIQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSVSLLDNKGLAEVSDIAEQVLNAVNKGFYKEATQLWGKAEMIIEKNTDGVNFYNILTKSTPDTSMESSLEFFRSPLVRLCQRHVRHLQGDALSQLMNGPIKKK... | Function: May be involved in vascular wall and kidney homeostasis.
Sequence Mass (Da): 51175
Sequence Length: 452
Subcellular Location: Secreted
EC: 3.4.16.-
|
Q92963 | MDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT | Function: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation... |
P70426 | MESGARPIGSSCSSPAALSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLKQLRQVSKEEGLSLAREFSCPFFETSAAYRYYIDDVFHALVREIRKKEKELVLAMEKKAKPKNSVWKRLKSPFRRKKDSVT | Function: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation... |
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