ids
stringlengths
6
10
seqs
stringlengths
11
1.02k
texts
stringlengths
108
11.1k
Q46108
MEVKAKQLDSVNATASVKIPSGMIKSEVENLAKKASKSVKMDGFRPGKVPVSAVLKRYERELTQDAEQNLFKSAVNSALQELKKENKELVGEPYFEKFDRKDGEIIAELILSFKPEIKLEGYEKLIPEYQTPKVSKKEIDEKKDELLKRFATPEAIKTKRALKEGDFAKFDFEGFVDDKAFEGGKAENYVLEIGSKQFIPGFEDGMVGMKIGEEKDIKVTFPKEYGAAHLAGKDAVFKVKLHEIQELKIPELDDEMLKKLLPGEEKASVEVLDEKLKEQIKNEKLFKLVNDELKGKFADALIEKYNFDLPKGIVEQETDM...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 50968 Se...
Q3AF97
MKVTKETLEKSRVELTIEVEAEEVSKAYEKAYKKIAQKVVIPGFRKGKAPRVLVERHVGKEYILEEALDELLPESYVKAVNEAGIEPVDKPEVSLVSYGVNEPLVYKAVVDVKPEVELGQYTGLEVTKMPVEVTDEEVEKELEYLQNRYAKLITVEDGEAKFGDIVVIDFAGKMNGEPLEGGSADNYRLELGSKVFIPGFEEQIVGMKPGETKEINVTFPEDYQKEDLAGKPAVFTVTLKEIKRKELAPLDDEFAKDVSEFSTLAELKEDLKKKIAQTKENISREKMEAEVVEKAVDNANVEIPASMVNHEVEHILHHFE...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 48608 Sequence Length: 4...
P0CAX0
MQIVEKSGEGLSRVFGVTVPASELATRLEARIAEVAPQMNVKGFRPGKVPTAHVRRLYGKALMGEVIEQALNETTTKVLEDNKLRPAGQPELNPSSDMDKVIAGGEDLSFDLAVEVMPEFEPIDPTSIELVKPVYKVSDEEVQEALDELAKQARTYEPRTGKSLKAKDGDQLLIDFVGTIDGVEFAGGKAEGAELVLGSGQFIPGFEDQLVGAKPGDDVVVKVKFPEEYQAKDLAGKDAEFATKVQEVRAPVDGKADDELAKRLGLSDLAALTELLKSNLAGRYDNSSRFKLKRALLDVLDTKHDFPLPPRMVDAEFAGI...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 49767 Se...
P56420
MNLEVKKIDTANARLSAKLSIENLEKRYDKIAQKIAQKVKIDGFRRGKVPLSLVKTRYQAQIEQDAQEEMIQEVLKNAFKELGIENKDLIGSPNLTKFEKKDTHFEIEADIGLKPTIVLDKIKECVPSVGVEVPNEEKIDERLKQLAKDYAKFVDTNTQRKAQNDDKLTIDFEGFIDNAPFEGGKAENFNLILGSKQMLEDFEKALLGMQAGEEKEFPLTFPSKYHAEHLAGKEAFFKVKLHQIQAREMLEINDELAKIVLANEENATLKLLKERVEGQLFLENKARLYNEELKEKLIENLDEKIVFDLPKTIIEQEMDL...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 51989 Se...
A9AUT1
MKVTTEQLPKRIVALEIEPDAATIEKELNKAAQRIASKVAIPGFRKGKAPRFIVENYYGKAAILEEATDEIINVAFRAALEQENIKPVAQASLEKLEPEPFRFRILVPVEPEVILPDYKAITVDLTEEPVTDATLEVALDQAREKHVVLSAPEGEPEAAEGDQLTATVQTLVDGVPLHKLDEEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEGEPTTLIMEERRIVPELYAGLKGIKAGETREISAHLPADHPDARVADKDVVFKVTVSEIQNRQLPAWEELPGLEEFEGDLDAYKADL...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 53732 Sequence Length: 4...
Q31GF2
MQVTVEKPETGLEHKINVTLPAGDLDSKVEQRLAQMRRTVKMDGFRPGKVPMSVVKKRYGGQVRQEMMGETVQQSFYDAVAKESLNIAGYPQFQELDEKDGHIVYSATFEVFPEVELPKFSSLKVETVTSEVTDKDVEKMVTRLREQKMAWKPANGNKKAKEGDQVIIDFVGKKDGEEFEGGKAEEVPLELGSGRMIPGFEDGIIGMKKNEEKTIEVTFPEDYQSDELKGQTVTFDITVHSVQTKVLPEIDEEFVKSFGIEEGTEEALVNEIRSNMEKELKRSVENKNRTAVLDALAEKVEVELPQAMVDQEASALMERQ...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 49093 Sequence Length: 4...
B2GGB4
MKSAVEKLNPTEAKITIDIAYTDLKPFVQETYKELANQIQIPGFRKGKVPSKLIDQRVGFDFVVENALNEGLNAFYQQALTENELTPLSQPQVEVLSKPEENDREADTKVEISVAIRPEIELPDYKGLEIQVEAREATAEDEQKALDELRARFGTLKTVDRPAAEGDHVTLDLQALVDGEEVDAANDLSYEVGSGTMLEGIDEAVTGLSAGEDATFETTLAGGEHSGAEATVKVKVTAVKERELPEADDEFAQLASEFDTIAELKEDLKKQAAESAVVEQGIEARDKVLDKLVELIEVPVPEKVIEDQLAQHFDSEQAQA...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 48943 Sequence Length: 4...
Q1IRD7
MTTEASNPEVNATAEVAVPVNPLLRSVTVEIPSDVVDAERNKHVQQYAKLARVPGFRKGKVPPSVIRTRFAQDINEEIVRTLIPHYFREETGKQNLQPVSQPQVTDLHLHDGEPLKFTAEFEILPEIPTTGYENIKVEHPPVEVTDAEIEDTIKSLQEQRATYDPIEDRAAEDGDFVQISFEGRDKSDPEAKPVEVPSIMVELGGSNTVQEFTENLRGTKAGDEKTFDVVYPADYGDQRLAGKSVEYHVSVKSLKKKIFPELDEAFISELGADVKTPDELRAKIREGAEHEKKHHAEHEGKDKLVDALVKLNDFPVPESM...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 49200 Sequence Length: 4...
C5CGV0
MEKNVVKAEKNVEIVEFTFGPDEIAEAENEIVRYVNKNYTIPGFRKGKAPKRIIETFFGENFRDMVLEELSRKIEDTLKDEELFIPAVIADRKIEGDVAVFVVELHREPKVELKDYTGLELSVPKQEEVLANYVDNKLEELRNEAAIVEPKDGPAEIGDVINIEYTIEKDGKIIADHKTQEILIVEDDDRPIVTNVIGKKKGDIVEFDRTFENSNNKYHYKIEIKEVLKRTLMELNDEFAKSVASEVNTLEELKKKLEEEGLEAFESWKKDFLRQQVQDKLAELVELEISEKTLDYFVNRAIENAKKENTYDSYLKQAGS...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 50877 Sequence Length: 4...
Q88KJ1
MQVSVENTSALERRMTIAVPAERVENEVNKRLQQTAKRAKIAGFRPGKVPMTVIRQRFEADARQEAFGDLVQASFYEAIVEQKLNPAGAPAVEPKSFEKGKDLEFVAIFEVFPEFTVAGLESIKVERLSAEVADSDLDNMLEVLRKQNTRFEAVERAAQNDDQVNIDFVGKVDGEAFAGGSAKGTLLVLGSGRMIPGFEEGLVGAKAGEERVVNVTFPEDYQNLDLAGKAAEFTITVNSVSAPVLPELNEEFFAQFGIKESTLEGFRAEVRKNMERELRQAIKTKVKNQVMDGLLAANPIEVPKALLENEVNRLRVQAVQ...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 48517 Sequence Length: 4...
A9WUW4
MKSAVENLSPTRVKLDVEVPFEELQPSIAEAYKTIAEQVQIPGFRKGKFPNRLIDQRVGRGYVLETAINEGLNGWYQNAVAETGLRPLSRPEVEITEVPDPAATDGELKFKVEVDVRPEVELPDYAGITVEVAPAEQSDEDRQKALDDLRGRFGTLKPADRPAAKDDFITIDINAKIADEDVDSATGLSYQVGAGTMLEGLDEAVEGLSTDEEAIFDTKLVGGEHAGEAAQVTVKLTAVKVRELPEADDDFAQLASEFDTIAELREDLVKQVNQSKTVEQGVEARDKVMEKLVELIEVPIPESVIEEQLEQHFDPANAHG...
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. Catalytic Activity: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0) Sequence Mass (Da): 51532 Sequence Length: 4...
Q6F880
MRSALPTFDEIWQRKFRHRLLIQAQQFPADTVFLIGCSGGMDSMLLLHLMSELFPHKVRAIYIDHQLQSSSRAWGVFVQNFAQQSHIPFTIQPVIVDTGNLENQAREARYAAFESHLKSNEVLVLAHHQQDQTETVLLRLLSGSGVKGLGAMKEIEQKKNICCWRPMLSVSRQQIEHWVEHLKIPYIQDLTNFDTTYDRAWCRETVWPVLQKRFPKMQEAISRTSILMQDADEILHEVLQQDLNQCGDLNHLDLSRLQQLSLARQRQLLSFWMKGKAIYRPAFEMVERVQQEVICAKADAKAALHWNHHYYVRYQNILYR...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q8U9L7
MPVDARTPNEKTVAPLAAASAFVESLRKPTHILVAISGGSDSTGLLLALQEAKAADDDGLRLSAVTVDHALRPESADEARKVAMLCAELGIPHTTRRWDGPKPASGLSEASRLARYRLIADVAREIGADLVVSGHTIGDQRETVAMRAARSGGSDNLGLSGMADAVLYDAHLWIMRPFLACERQVIRDYVSSRSRHWLDDPSNENIRYERVRVRQTLPHSPIALDDSTAVRRQMLSERTAVFLRERAQVFHAALARLADDDVNPDLPEFRHGLAALIAALGGRSYFPAASSMERVLRFLKTGETGRMTVGRVLLDRRRDG...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q5WAE0
MEARVEQFIENNRLFGMETNVLVAVSGGPDSMALLAIMANLREKWKLNLFGVHVNHRLRGEESNKDAELVQSFSARLGVPCNVKDVDVAAFKAEHHVGTQQAARALRYQVFQGEMERVHATVLLTAHHGDDEVETAFMKLTRGTTPLTKLGIAATRPFANGVLARPLLEETKRSIVAYCHEKAIPYRIDQSNFSDAYTRNRFRMNMAPYLVEENPHIHKHIGRFDRWQEEDNHYLMEQAKAHLDQILTKKSEKSIELEIQALCLAPFPLQRRMIHLILNYLHLNVYGVNDMRVFPDAIEQIQAFLQTSAPSAQLDLPGRV...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q0A7K1
MAPTPELSPETLARHLAVLGPASGYCVAYSGGLDSTVLLHLMAALSAARELPLRAVHIHHGLQPQADAWAEHCRQQAAALGVDCLVLPVEVRRDSGEGLEAAARQARYAALASHLQSGEALLTAHHADDQAETVLLHLLRGSGPRGLAGMRAQRPLGRGRLLRPLLPWPRERLRAYGDTHALCWVEDPSNAHVAHDRNWLRHTLWPVLTQRWPDASRRVGRAAGEQAEAEALLRELAGEDLARHPPGPGLAVSVLARLSPARARNLVRHWLLMSGLRPPPRARLEQGLADLIRAGRDRQPVLTWPEGELRRYRDRIHRLP...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q5P9R1
MSGVRIPLFPRFIPHGTVKLESAALKKLNSLELSGGYAVAVSGGVDSITLLNLVAALHKTQATSRPVVLTGNHGFRAEADHETRFVQKRAVALGLDCEILRWNRHRTSSKSQETAREIRYSLLHQWCTEHSVKFLLTAHNKSDQAETVLMHLERGSGIDGLSGMHERSVFGDITIYRPLLGFTRQEILEYATQKQLSWVEDPSNQDPKYRRTFFRNLIAESKNPGVVVDRLCRTTSHMHRALACILHYVRSSLDYCLEFSPLGFITVKSQELRSVPEEIASRLLLLSLMAMGGKDHKPRYSAFWPILTKILQGQDFTPRT...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
O67728
MNPESRVIRKVLALQNDEKIFSGERRVLIAFSGGVDSVVLTDVLLKLKNYFSLKEVALAHFNHMLRESAERDEEFCKEFAKERNMKIFVGKEDVRAFAKENRMSLEEAGRFLRYKFLKEILESEGFDCIATAHHLNDLLETSLLFFTRGTGLDGLIGFLPKEEVIRRPLYYVKRSEIEEYAKFKGLRWVEDETNYEVSIPRNRIRHRVIPELKRINENLEDTFLKMVKVLRAEREFLEEEAQKLYKEVKKGNCLDVKKLKEKPLALQRRVIRKFIGEKDYEKVELVRSLLEKGGEVNLGKGKVLKRKERWLCFSPEV
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q5P2I9
MLVAAAVAPRQRLCVAFSGGADSTTLLHLLARLRPRFGFDLCAAHVHHALSPNADAWLDFCARQCAALDVAFHPFREQVARDHPAGLEAAAREVRHAALSRVTCDWLVFGHHQDDQAETLLFRLLRGAGVRGAAAMAAIEPGFPGRLRPLLGVRRADIRAFAQAASLEWIEDESNADPRHARNFLRHHVFPLFGEAFPGAVPALARASGHFREADGLLGDLAALDYAACGGSPWLRDRLLMLSDERVRNLLRWRIRQMGCEAPARARLVEAVRQLRATHAPLYLPLGTAACCTYRDRLWLEPQRDGAPEQPLPWRQEPAL...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q2NIN4
MENIKLACSLETNQTYIIAVSGGVDSMALLHYLVAQKIKLQVVHFNHLTNSNTWKNKELVKNYCLQNSLGFHYFELNCPQKNFQAQARLLRQQKLMQIAAKHRTPFILTAHHLDDLAETILQKISRSSTLLGYSGMQIQTSWTDFIFLKPFLYIPKAKIISYAAFYKIPFLEDYTNQKLTYQRNQIRHQVIPYLKTQTSFLQNIQKYQQTLLQAYNFIRKQTLLFLTKHTNHSCNQPNSIALAPFLNLDLVIQKDIILLLLEQKNITQSFIFIQNIIKGINNPYKPNLSWHLNSDWHLIKDYKHIKLMNPALPLPFALTK...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q81VX7
MKDTFVEKVDDFVRQHDVLKERSTIVVGVSGGPDSLALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKGLGVICETIRINVSQYQKQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVNYCNELKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPTFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGD...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
B3CUJ5
MNIEVDFCHNMECFGAFEKNPKLAIAVSGGSDSLALMLLVKHWNEKVKGEITILTIDHHLRSESTSEADYVSSICQNIKLQHVTLHWIHKGITGNIQAQARKARYQLLTNYCQEHDILHLITGHHADDIVENFFIRLLRGAGLAGLSSHNLFFVNNVRIIRPLFNITKQDLKKYLEQQNIKWINDPSNSSNKYLRTQVRDLLKSMLISFQHNFTVELLKKRIMLSQMHLTQALESVNNEIIHYVVHVVKIYSAGFAVIDRKLFKKASPEARYAILSYLLMIVGANTKPPRFSSLQRISLHDIQEYNTYKTLHGCIVEYSI...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q7UA26
MGEQRPLALAWSPWHDRLHRRLHQHPQLLPQRQPLLLAVSGGQDSMALLVLLQELQRLHHWPLNIWHGDHGWHSGSAVIAADLRSWCQQRDLPIQVDQAPQGSTASEASARHWRYSQLQQRAEELGADVVTGHTASDRAETLLLQLARGTDLAGLGALRPVRPLFNDSPDGAQLRRPLLGFSRADTAAVCRDLQVPIWHDPSNQSPAFARNRIRAEVLPVLEQLHPGCSQRMANLAERTSQLRDTQQELSQLALQPLRTSTGLDRRRLGALQPSTRRQLLVIWLAQQGVTALNAALLEQLTDRLALSAAGGSCDLPGGWR...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q6MDI6
MSCICLKNEKLNVINQVKRFIKKYCKSTQPLLLALSGGADSLSLFYCLLACRLEGILSFHVAHVDHGWREESAKEATILKNLAEQHQVPYHQLKIDLSQLAGNLEDACRKQRQKFFKEICLQNNLQAVCLGHQENDQVETVLKRILEGSHWSHFDGLKERMWHDQVQFLRPLLGIQKDEILAFLKGNQLKAFEDGTNCDERFMRARMRRTIIPDLNRSFGKKIDNSLVYIASEMSELKNFFLGRVSPLLGQIVKGPFGVYLNLANHPSIDLVEIKYLLRLISEQELFFLSRQILQRASEAIEKLEPQLSFEMGTKKIVID...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q6D8C5
MDRTEPDDELLQTIVTQTAGCGSILLAYSGGLDSSVLLHLLVTVRQRSGQTIRAAYIHHGLNPLADSWAEHCRQQCERWQVPFSSLAVTVEAQNGGIEAAARTARYQALQVHLKEGETLLTAQHLDDQSETFLLALKRGSGPAGLSAMAANSFLGHHRLVRPLLGFSRLQLEAYAQRHQLRWIEDDSNQDERFDRNFLRRQILPRLTQRWPHFPSAVARSAELCAEQEQLLDELLEESLRTLRQPDGALSIDGLVPLSPVRRFALLRRWLAQQGATMPARDQLQRLWDEVAASRRDAEPILQLNQMQIRRFRQHLYLLPL...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
C0QU23
MVEKKFLEAVKKYSLISEGDRILVAFSGGIDSTVLTYLLIKFRDHLKISDIYLAHLNHSLRKESDEDQRFCEDFAKKYGLEIFTKKVDIKSLAEKEKKSIEQKAREERYSFFRKVMEERSINRLATGHHLSDLVETMIMWFIQGNRKGIKGFRPKERDIIRPLYLINKDQIENYAREKGIEYRIDITNFETDFLRNRIRHNIIPHIKGINPSLEGSLLTLSYFLSLDDQYLEEESEKISQKFLNGKIELEELLVYDKALVYRAIQNWIYRKTGVYPSYRQIMDIMEIIEKKEGTKSIRLSPEYNLIRRYSTLYIEKVKEK...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
A9BJK2
MILQDFEKKIFKFIRDYKIFNKYDKILLGVSGGKDSMSLLHVMSKLSKTMGFEISVAHLNHCMREEADNDEAFVRQACWKLKIPFFSKKVDVFTYSKKNKVGVEVAGRKLRYEFFYETLRRLSYNKIATAHHMDDLFETMIYRILRGTGIYGLGGLIPIEEEITKPMLCVDLEEIKNYVTINNIEYVEDKYNYSLDYARNKIRYEITPLFKKINPRYKESFFRLAKIIWSYREEVKRKFEERSEISKDSLKLRLENDFFDGEIIRIAFLKFGKYPPNMEETEKIIKMRKGGVRKINGLSITKKSDSLLVKI
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q7N8N0
MANIDERLFVTLAKQLGEYKKILVGFSGGLDSSVLLHLLVNWRNQHNQKIQLRAIHIHHGLNLKADQWIEHCQLICDDWQVEFHSARVTIDARQKGIEAAARDARYQVFKSELQKDEVLVTAQHLDDQAETFLLALKRGSGPAGLASMPSIAVFADTLLLRPLLDYSRNELEKYASKHRLNWIEDDSNQDDRYDRNFLRLHIMPLLNQRWSHFPKAAARSASLCGEQEQLLDELLNESLKELITQDGALGIVSLAVCSEAKRNALLRRWFGYHGMKMPSREQLNRLWYEVALARTDAEPRLQFGKYDVRRYKQKLWLVPQ...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
A1VRB1
MAAPVASLNPALAGIDSLFSAFPSSSSLPLGVAYSGGADSTALLLAAAERWPGQVQAFHIHHGLQAAADDFVRVCESVCAKAGLPLHIVQVDARHASGESPEDAARRARYAALATAATARGMQGVLLGQHADDQVETMLLALSRGAGLPGLSAMPASFGRGGMVFYRPLLHIPSAVLREWLVEQPIEFVDDPTNTDERYTRNRIRARLLPALAQAFPQFHATFARSARHAAQAQAVLVEVAAQDLAVVGNPPAIKALQALSPPRQANVLRHWLLLQYATPSAAQLEQLLHQVAACTTRGHRIHLKVASGHVTRLGGSLCY...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
B2RMB4
MKISLTNRVRTTIRERKLFREGNRLVLVALSGGADSVALLCVLRELGYETVAAHCNFHLRGVESDEDAAFVEGLCRDLDVPLHRIDFDTVRYARERSISIEMAARELRYEWFGLLRKELAIEYVAVAHHADDNAETMVLNLCRGTGISGLCGMPYKRNDGIVRPLLDATRDEIEAYLLDQKITYRTDSSNEDTRFRRNLVRHRIMPLLKELNPSLQEALLRTRENLEGVAAFFSKATEDFHNTLRATASISIREVKETPAPFTLLYDLLHPYGFNRDQIREVVTSLDNPPGASFFSSSHRLLRERDRLTVLPLSPKMEVP...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
P51383
MFLDSFLHKKFFSTIEKKSLLPSKSSLLVAFSGGQDSLTLVKLLYDLNPFYRWRITLIHFDHRWRWDSMLASKQVFSFARYYNFPLYYFECPDYLNTEEASRKWRYTTLIDLAVKNNFTKILLAHTATDSSETLLSNLFRGTSLDGLASIGWSCQLAQSVYIVRPLLNFYRFETSWFCRKYYLPIWVDRSNYDYIMFRNRLRQELVPYIKSYFQPNLEERCYSLSSLVKYDTDFLEQEALRIYFILIHQDLIAINHTALRLLHLSVQSRIFKIFFIANLNFNPNSRQIEDVIIFIKQNILSQINMNNYILVMDDIWFYVG...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q7V9L9
MTNSTKVEKPWTKWHERLHKSLKSKSNLLPYGSSLLISVSGGQDSMALLKLILDLQRIYEWKVHVWHGDHGWHNQSRQIAEELEEWCKCQKLSFFCNRTNKQKVSTEEDARNWRYKSLIQQAKTLSKESPSLPCERVLTGHTANDRTETFIMNLARGAHLKGLSSLREDRTLETKIQLIRPILRFSRQETIQICDEMDLPIWIDPSNSNIAYSRNKIRAEIIPVLESLHPQSTIRISNLAERLTSLQKDQHQLAHLALGALLTSTGLSRSKMTKLSKTVRAIILAQWLEDNKAPLLSSKQLEELSQKIGKNKGPGNMDIS...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
B4F252
MELKNCPLINEIKRQIGSHTHILVGFSGGVDSTVLLHGLVCLRDKYQLPLELTAIYVHHGLNSKADDWLTHCEHFCHNWQVSFISERVQVNGKEGGIEQGAREARYQAYRQYLQPNQVLVTAQHQDDQAETFLLALKRGSGPAGLSSMPAKMPFEQGYLLRPLLNITREQIEAYAHEHGLLWIEDDSNQDDRYDRNFLRLHVMPLLTQRWPHFSQAVTRSAALCGEQEALLDELLDVELQQLIDEHQSLDINLLSRCSEIKRNALLRRWFAKCNKSMPSRSQLSRLWQEVALAKADAEPRLRFFQDEVRRYQQRLYLVPV...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q7V987
MASSSSTQLPWSAWHARLHHKLLANPDLLPAKASLLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQEVLPVLESLHPGCSLRMAALAERLNHHHADQQAIAMLALNNLSKQNGLCRKDLAQLPITARTTLLAYWLKRSGAPSLPAVQLEQISQSIAPGKPPG...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q7UZL1
MSDKNSSQKNWTSWHHLLHKEILGNKTLIPDGANLLIAVSGGQDSMALLNLINDMKTQHNWFVNVWHGDHQWHKKSAKYALELKSYCNKKNISFFFDQANKNNISSEEKARDWRYKKLSERANQLLIENQKEIDIYLLTGHTNTDNAETFLLNLARGSNYAGLSNINKKRLLKHHIFLIRPLLIFSREDTKKFCQLQNIPIWEDPTNCDLTIKRNIVRKEIIPILETMYPGCSKRINSFAEKMSNYKNEQNDLSKLASLYCEDAIGVKRELLNSLCIEARCTILNTFLKKDCTKQLSSKNLTHLASSILVKDRGKIDLPD...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q46ID9
MRLHKRLKQNKSLLPSNSTILLAISGGQDSMALLKLIIDLKRLHQWQVEVWHGNHQWHAKSEETEDELKLWCLKNQISFHSNKADKKEVANEEKARDWRYKNLIMKAKFLSSKNIHFPCTRILTGHTATDRAETVIMNLARGTDLTGLTTLKEQRTIENNIDLTRPLLIFNRNETLEICKDFNLPIWIDPSNENINLTRNKIRKEILPILNSIYKGADSRIASVANRLESYNEDQKLFAKIAIQFCQGEKINSLSRIKLFGLTNSIRQIILSNWLKTMGVKRVTALQIEEINTKVSQRKPPGSIHLHGDFLIRWNKEAIY...
Function: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Catalytic Activity: ATP + cytidine(34)...
Q6FPU1
MDGTGISDGSSVTGDAAAGFPAGATQAPGSKQGMDLYFDNALQYMGEHPVLAGVGGFLALYVGAGVYKGVQTRLNGGKAATQFLKGGFDPKMNAKEALQILNLKENNLTTKKLKEVHRKIMLANHPDKGGSPYLATKINEAKDFLEKKGIVRK
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity). Location Topology: S...
Q6PBT7
MASTMVAVGLTLAAAGFTGRYAVRAMKHMEPQVKQALEASKSAFGSGYYRGGFDPKMNRREASLILGVSPTANKTKIREAHRKLMILNHPDRGGSPYLAAKINEAKDLLDGQAKK
Function: Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling (By similarity). May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent...
Q6BH37
MAPFNMDIPTLAIPGDRNQSQAIELSQQAQQPQQPQQSQQAYTGHLQRKQADEGSAEYYFDKGCEWMGNHPWMTGMGVLGVAYFASGFVKSKQPGINGKAFVKGPFGQKMTPKEALQILNLKETNLSQAKLKEQHRKLMMANHPDKGGSSYLATKVNEAKDILEKRGGLKKK
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity). Location Topology: S...
Q54QN1
MATPIIVGATIAGIAYSSRFLIRVIQRAKSKQLFEMVSTPGFTVETIEDGFENKMTPAEAANILGLKEESTKEEIKIRHKLLMIKNHPDKGGSSYLATKINEARNVLSSKNSN
Function: Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling (By similarity). May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent...
Q9VTJ8
MASSVILAGLSVAAVGFAGKHLMRRMPQMTTKFNEALKNLPKYDAESMAASKYYKGGFDPKMNKREASLILGVSPSASKIKIKDAHKKIMLLNHPDRGGSPYLAAKINEAKDFLDKAK
Function: Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). Location Topology: Singl...
Q5B4H1
MASALTLGLGVATAAFLGRAGLVAYRRSKGGVNALGKAFYKGGFEPRMNRREAALILELPERTLNKEKVRKKHRQLMLLNHPDRGGSPYLATKINEAKEFLDKHT
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity). Location Topolo...
Q4I7T5
MASVMAWGAGAAVAAFLGRAGLVAWRRSRGGVGAMGKAFYKGGFEAKMTKKEATLILSLNERAITKDKVRKAHRTLMLLNHPDRGGSPYLATKVNEAKEFLDKNG
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity). Location Topology: S...
Q96DA6
MASTVVAVGLTIAAAGFAGRYVLQAMKHMEPQVKQVFQSLPKSAFSGGYYRGGFEPKMTKREAALILGVSPTANKGKIRDAHRRIMLLNHPDKGGSPYIAAKINEAKDLLEGQAKK
Function: Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling (By similarity). May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent...
Q9CQV7
MASTVVAVGLTIAAAGFAGRYVLQAMKHVEPQVKQVFQSLPKSAFGGGYYRGGFEPKMTKREAALILGVSPTANKGKIRDAHRRIMLLNHPDKGGSPYIAAKINEAKDLLEGQAKK
Function: Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling . May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May ac...
Q7RX75
MSSAVAIGAGVAVAAFLGRAGLVAWRRSRGGVGALGKAFYKGGFEPRMNKKEASLILSLNERTITKDKIRKAHRTLMLLNHPDRGGSPYLATKVNEAKEFLEKSV
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (hsp70-5) (By similarity). Location Topology...
Q9UT37
MSSAILLGVGIAATAAAGKIGVDAFRKYRNLNGGVKAFLKGGFESKMSRAEAIQILSLNNRTLTRQKIKEAHRRLMLANHPDRGGSPYVASKVNEAKSLLDADRSIRKFSSWALPVSKQRSMPSVLEAVKWLEYSSIPKA
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (ssc1) (By similarity). Location Topology: S...
Q6CEU0
MSTTPVQPLQSEPLMDSETGVAPQIEAPQVPEGPKKGIDEQIFDYFAEHPVQATAATLVGLYALGAVFKRPAAGARGQFFKGGFENKMGPSEALQILSLRDAGLTMNKLKGQHRKIMLLNHPDRGGSPYVATKINEAKSVLEKRGGLK
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity). Location Topology: S...
Q07914
MSSQSNTGNSIEAPQLPIPGQTNGSANVTVDGAGVNVGIQNGSQGQKTGMDLYFDQALNYMGEHPVITGFGAFLTLYFTAGAYKSISKGLNGGKSTTAFLKGGFDPKMNSKEALQILNLTENTLTKKKLKEVHRKIMLANHPDKGGSPFLATKINEAKDFLEKRGISK
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1). Location Topology: Single-pass membr...
O62250
MPWRTALKVALAAGEAVAKALTRAVRDEIKQTQQAAARHAASTGQSASETRENANSNAKLGISLEESLQILNVKTPLNREEVEKHYEHLFNINDKSKGGTLYLQSKVFRAKERIDEEFGRIELKEEKKKEENAKTE
Function: Regulates ATP-dependent protein translocation into the mitochondrial matrix. Location Topology: Peripheral membrane protein Sequence Mass (Da): 15276 Sequence Length: 136 Domain: The J-like region, although related to the J domain does not have co-chaperone activity. Subcellular Location: Mitochondrion inner ...
Q59ZW9
MAHRLLVNVIFTGASVFGRAFTEAYRQAAKASAAGAAGRPAKASSAGGIPVEEAMKILDLEKSELSLDKVEEKYEYLFNVNSKEQGNSFYLQSKVYYAMDTLKKELEYLEKLQNEKGAASN
Function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. ...
P20614
MAPLAALASSMLLLLWLVAPSRACTCVPPHPQTAFCNSDLVIRAKFVGAPEVNHTTLYQRYEIKTTKMFKGFDALGHATDIRFVYTPAMESVCGYSHKSQNRSEEFLIAGQLRNGLLHITTCSFVVPWNSLSFSQRSGFTKTYAAGCDMCTVFACASIPCHLESDTHCLWTDQLLLGSDKGFQSRHLACLPQEPGLCAWQSLRPRKD
Function: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP1...
P50122
MALFAPTVSGILLLLWLTAPSRACTCVPPHPQTAFCNSEVVIRAKFVGTAEVNETALYQRYEIKMTKMFKGFSALRDAPDIRFIYTPAMESVCGYFHRSQNRSEEFLIAGQLSNGHLHITTCSFVAPWNSMSSAQRRGFTKTYAAGCEECTVFPCSSIPCKLQSDTHCLWTDQLLTGSDKGFQSRHLACLPREPGMCTWQSLRPRGA
Function: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP1...
Q60453
RACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds. Sequence Mass (Da): 21941 Sequence Length: 196 Subcellular Location: Secreted
O77717
KAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKADGNGKMHITLCDFIVPWDTLST
Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds. Sequence Mass (Da): 9998 Sequence Length: 91 Subcellular Location: Secreted
P16035
MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. PTM: The activity of TIMP2 is dependent on the presence of disulf...
P30121
MGAAARSLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds. Sequence Mass (Da): 24356 Sequence Length: 220 Subcellular Location: Secreted
P0DTS9
MSVLETKLKSQMSKSAKIARNMNKLPDEIDRLRKRIERINKKRKPTSSNIRDLEKSNKQLVTKQQKLADLQVEYTKIEKKINETKINLQKEQSRNQKKLSSMLDKNTKGNEEIMEKLLTNSDQINEISNQIKKAVNQKEIIEYDVFLSHSSLDKEDYVSKISEKLIEKGLKVFEDVKVFEIGKSQTETMNMGILNSRFVVVFLSPNFIESGWSRYEFLSFLNREINEEHVIILPIWHKVSVEDVRAYNPYLVDKYALNTSDFSIEEIVEKIYQVIVNSKN
Function: Virulence factor that suppresses host Toll-like receptor 2 (TLR2)-mediated NF-kappa-B signaling upon infection . NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide . Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules . Able to reduce NAD(+...
B7UM99
MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADSVDSRDIPGLPTNPSRLAAATSETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADGTHAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGRGGSGHPMVTVASDIAEARTKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSVGAIAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQ...
Function: Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signal...
A5A627
MNLVDIAILILKLIVAALQLLDAVLKYLK
Function: Toxic component of a type I toxin-antitoxin (TA) system (Probable). Overexpression causes cessation of growth, induces stress-response, a number of membrane protein genes, and leads to cell death . Inhibits ATP synthesis, ATP levels drop drastically quickly after induction . Part of the programmed response t...
Q07352
MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSSSSSSHSGSDSPT...
Function: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis . Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter pr...
P23950
MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPSLSSRDSRFRDRSFSEGGERLLPTQKQPGSGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRALAGGRDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLSDHEGYLSSSSSSHSGSDSPT...
Function: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis . Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter pr...
Q805B4
MSTTLLSAFYDIDLLYKNEKALNNLALSTMLDKKAVGSPVSSTNSNLFPGFLRRHSATNLQALSGSTNLAKFCPNNNNNPLKDPAVSSTALLNRENKFRDRSFSENGERSQHLLHLQQQQQQQKAGAQVNSTRYKTELCRPFEENGACKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRQAPGAGERPKLHHSLSFSGFPNHSLDSPLLESPTSRTPPPQSSGSLYCQELLQLNNNNPCANNAFTFSGQELGLIAPLAIHTQNQSYCRQPCSSPPLSFQPLRRVSESPVFDAPPSPP...
Function: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis . Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter pr...
P47974
MSTTLLSAFYDVDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRRHSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPT...
Function: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis . Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter pr...
Q9ZD67
MLPPKIFFEKVKEIIWPIERKELKLFIPMALMMLCILFNFGALRSIKDSLVVPSMGAEIISFLKLWLVLPSCVIFTILYVKLSNKLNFEYIFYSIVGTFLLFFLLFAYIIYPNQDIYHPNDAMINNLIASYPNLKWFIKIGSKWSYALMYIFSELWSAVVINLMFWQFANHIFDTAKAKRFYPVLGMVGNIGLIIAGSVLVFFSSGQYIIDSELLTDSYNSSSNNSIMLQPIISIIVTAGIIAMFLFRIINKFILTNSINVLDVKKVAAKTKTKLALIESIKLIIHSKYIGRIALLIICYGLLINIVEGPWKAKIKELHP...
Function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 57182 Sequence Length: 501 Subcellular Locati...
F1NZP5
MGPGWRAPSAALVGGSVALFGALRRAALALPRPAAVRSRPGRVWRWRNLLVSFAHSVLAGLWALFSLWQSPELLSDIQDGYSVSGHLLVCFSSGYFIHDSLDIIFNQQSRSSWEYLVHHAMAISAFVSLIITGRFLVAAMLLLLVEVSNIFLTIRMLLKMSNVPSPALYEANKYVNLVMYFAFRLAPQVYLTWYFVRYVEVQGQGAFLMANLLLLDAMILMYFSRLLRSDFFPSLRKGSVGRDVDGEKFLID
Function: Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity). Does not appear to have any effect on LCPUFA...
Q96CP7
MPRLLHPALPLLLGATLTFRALRRALCRLPLPVHVRADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFLTE
Function: Regulates the composition and fluidity of the plasma membrane . Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity . Does not appear to have any effect on LCPUFA synthesis . Location Topology...
A8WGS4
MELNSVILTTGSSVGFFKLVNYGLGKLPIPETARRNAWKWNNISTSFVHSLITGVWSVLCFCMHPQMAEDLIETHSVFSHALVSVSIGYFIYDFLDMVINQKIIHSWELLFHHVVVITCFGISVLTCRYVGFAVVALLVEINSVFLHLRQVLRMANLAKSTFYRVNSMINLGTYVVFRINTLAWMTRWLVLNRDLIPLFSYTIGSVGLAIMTAMNIVLFYRLMRSDFMKASREKELRKEKEKEKDM
Function: Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity). Does not appear to have any effect on LCPUFA...
A6NGC4
MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDNGPVTSNSSTLSLKD
Function: Regulates the composition and fluidity of the plasma membrane . Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity . Does not appear to have any effect on LCPUFA synthesis . Location Topology...
Q9ZD47
MTINASNIENSFSKINSHFSKLTDYIWPIKRHEISKFLFITLLMFCILFIQNLIRALKDSIVTTMIGAETISFLKFWGVMPSAFLITVIYVKLVNRMKAENIFYLIISIFLTFFALFAYVIFPNHEMLHLRPVTVHNLTASLPNLKWFILLLSKWSFSLFYIIAELWPNVVFALLFWQFVNNITTVEESKRFYPLFGLLSQTGIYLAGHFLENLSNINYYVTNKFALQSSFHTLSIQIILTIVLILGIVSIKTFWLLNHKVLDKKHMALLRFKTKNKSITIAKSFQMILSSRHIRLIATLLICYGIAINLVEGPWKAAAT...
Function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity). Location Topology: Multi-pass membrane protein Sequence Mass (Da): 58208 Sequence Length: 512 Su...
P50694
MMKTLVVVLSLSLTILSFGGAHAATISFKNNCPYMVWPGTLTSDQKPQLSTTGFELASQASFQLDTPVPWNGRFWARTGCSTDASGKFVCATADCASGQVMCNGNGAIPPATLAEFNIPAGGGQDFYDVSLVDGFNLPMSVTPQGGTGDCKTASCPANVNAVCPSELQKKGSDGSVVACLSACVKFGTPQYCCTPPQNTPETCPPTNYSEIFHNACPDAYSYAYDDKRGTFTCNGGPNYAITFCP
Catalytic Activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans. Sequence Mass (Da): 25707 Sequence Length: 245 Subcellular Location: Secreted EC: 3.2.1.39
Q9BXR5
MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIY...
Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). Location Topology: Single-pass type I membrane protein Sequence Mass (Da): 94564 Sequence Length: 811 Subcellular Locati...
Q6R5P0
MPRMERHQFCSVLLILILLTLVSLTLTGWAWTIPDCIIADSLLFPNLSYYIPFCTSAPGLHLLASCSNVKNLNQTLKRVPRNTEVLCLQGMVPTLPAKAFIRFHSLQLLRLQLRTTSVTSRTFQGLDQLQYLFFDHHAPCCLSLFLSPNCFESLRSLSSLSFQGYCLTYSQSIYLPTSLRHLTLRNSCLTKFQDLQRLFPDLLLSTSSTPNIKPGAPFLETLDLSYNLQLKQAGVRDLYGLTLHSLILDGTPLKALDLTDSGLLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQNILENGEIPGYKALEFLSLH...
Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Location Topology: Single-pass type I membrane protein Sequence Mass (Da): 105873 Sequence Length: 926 Subcellular Location: Membrane
Q6QNU9
MGRYWLLPGLLLSLPLVTGWSTSNCLVTEGSRLPLVSRYFTFCRHSKLSFLAACLSVSNLTQTLEVVPRTVEGLCLGGTVSTLLPDAFSAFPGLKVLALSLHLTQLLPGALRGLGQLQSLSFFDSPLRRSLFLPPDAFSDLISLQRLHISGPCLDKKAGIRLPPGLQWLGVTLSCIQDVGELAGMFPDLVQGSSSRVSWTLQKLDLSSNWKLKMASPGSLQGLQVEILDLTRTPLDAVWLKGLGLQKLDVLYAQTATAELAAEAVAHFELQGLIVKESKIGSISQEALASCHSLKTLGLSSTGLTKLPPGFLTAMPRLQR...
Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. Location Topology: Single-pass type I membrane protein...
Q6R5N8
MSGLYRILVQLEQSPYVKTVPLNMRRDFFFLVVTWMPKTVKMNGSSFVPSLQLLLMLVGFSLPPVAETYGFNKCTQYEFDIHHVLCIRKKITNLTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENLTLLNLVENKIQSVNNSFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISDFSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLVSLTHLSFEGNKLRELNFSALSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLR...
Function: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secre...
P30974
MSEIVDTELLVNCTILAVRRFELNSIVNTTLLGSLNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWL...
Function: Receptor for tachykinin-like peptides. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 58020 Sequence Length: 504 Subcellular Location: Cell membrane
Q86T26
MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV...
Function: Serine protease. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 46337 Sequence Length: 416 Subcellular Location: Cell membrane EC: 3.4.21.-
Q14C59
MYRPVIASRKSIPPWLIILCVLGVLAALGIIIGLLVHFLAVENKIYYYQGGFKVLDIPYDRNYERETSLESNYLSKILENKMVEAFQNSNIYKQYINSQVITLVPDNNSVTAHIWLVFKDPWSNKENLRRRIESILRQMLENNPESLTTDPGSLKLTEISKVDAEKIINNRCGRRPRMSATYDRITGGSTAHKGEWPWQASLRVNGKHYCGASLIGERFLLTAAHCFQGTNNPKNLTVSFGTRVTPAYMQHSVQEIIIHEDYVKGEHHDDVAVIKLTEKVSFNNDVHRVCLPESTQIFPPGEGVVVTGWGSFSYNGKSPL...
Function: Serine protease. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 46713 Sequence Length: 416 Subcellular Location: Cell membrane EC: 3.4.21.-
Q1JRP2
MARGQPRRSEEQWTALQNRTECKTKIKLTRCGKITLGILTAVLAAVLIGLIAYFAACGKDSFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHAVLKFKACYRNNVEKYWESVETTLYQKLKGQTGLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFIRAANPKDWKVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVV...
Function: Serine protease which has a preference for Arg or Lys in position P1 and uncharged residues in positions P2 and P3. Shows specificity towards FGF2 in vitro. PTM: Proteolytically cleaved via an autocatalytic mechanism. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 48073 Sequence L...
O60235
MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHT...
Function: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) sp...
Q8VHJ4
MYRPRSMVSPSRFFNPFMVALIVIITVGLLAMTAGLLIHFLAFDKRAYFYHSNFHILNVDYTEALNSPATHEYRTLSERIESMITDAFRESNLRSEFIRTHVVKLRKEGSGVVADVVMKFRSSKRNNKKAIKTRIQSVLQRLSSSGNLEIAPSNGITSLTDQDTENVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLNNVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTATFGVSTISPRLRVRVRAILAHAEYNSITRDNDIAVVQLDRPVTFTRNIHRVCLPAATQNIMPDSVAYVTGWGSLTYGGNTV...
Function: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Preferentially cleaves the C-terminal side of arginine residues at the P1 posit...
Q9UL52
MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALK...
Function: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. PTM: N-glycosylated. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 47696 Sequence Length: 423 Subcellular Location: Cell membrane EC: 3.4.21.-
Q5S248
MYRSCVVRARKRTCVEPWVIGIISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLSFTSDKLYSEFGREASKNFTEMSQRIETMVKHAFHKSPLRGQLVKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPETVHKIIEYVLHEKLKYATGPPNVDPESVKIKKINKTESDNYFNHCCGTRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRWSATFGATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALK...
Function: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. PTM: N-glycosylated. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 48065 Sequence Length: 423 Subcellular Location: Cell membrane EC: 3.4.21.-
Q6ZWK6
MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIK...
Function: Probable serine protease. Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 49410 Sequence Length: 438 Subcellular Location: Membrane EC: 3.4.21.-
Q5QSK2
MYQPGILGRRKRVCKPWTVALTTTAALLALAVLIGLLVYFLVYEEKTHYYQASFWIPSIKYSSDLSEEQSKLQINLKQKINNEIDVIFQRSSLKHHYVKSQVVNFRPSNDGVKADILIKFQIPRKNADTLRSEADSILNKKLQSSQSFLKRDISLPYLREMNAAQAEHILNSNCGLGMEYPRIARIADGKPAGSNSWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPKLWTVSFGRTLGNPLTTRKVESIIIHENYAAHKHDDDIAVVKLSSPVLFSENLRTVCLPEATFQVLPKSKVFVTGWGALKANGPFP...
Location Topology: Single-pass type II membrane protein Sequence Mass (Da): 46593 Sequence Length: 417 Subcellular Location: Membrane EC: 3.4.21.-
Q8QFN3
MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVKTAKRGYAMILWFLYIFVLEIKLYFIFQNYKADKKNLETVARKALTLLLSICVPGLYLVLVALDSMEYIRTFRKKEDLRGRLFWVALDLLDILDIQANLWEPHRTGLPIWAEGLMFFYCYILLLILPCVSLSEISMQGEHIAPQKMMLYPVLSLVTINIVTIFIRAINMVLFQDSRVSTIFIGKNIIAIATKACTFLEYKRQVKEFPQNAIALELQQNSLSHNQTLHSTQGIPHEPSPTSEILDT
Function: May play a role in MAPK signaling. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 35676 Sequence Length: 312 Subcellular Location: Membrane
Q9BTD3
MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALSLELQPPPPQRNSVPPPPPPLHGPPGRPHMSSPTRDPLDT
Function: May play a role in MAPK signaling. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 35814 Sequence Length: 319 Subcellular Location: Membrane
Q5ZK32
MAPKGKAGTKGKKQIFEENRETLRFYLRIILGASAVYAAVNLVVFYPAASAWTWLAFAFSSAVYGASYRSMSSMARPAFADDGSLADGGIDLNMEQGWQSECPHPHEPRHLKDVILLTAMVQVLSCFSLYVWYFWLLAPGRALYLLWVNILGPWFTAESSAPGQEPNEKKQRRTGTPPE
Function: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 19967 Sequence Length: 179 Subcellular Location: Endoplasmic reticulum membrane
Q9BTX3
MAPKGKVGTRGKKQIFEENRETLKFYLRIILGANAIYCLVTLVFFYSSASFWAWLALGFSLAVYGASYHSMSSMARAAFSEDGALMDGGMDLNMEQGMAEHLKDVILLTAIVQVLSCFSLYVWSFWLLAPGRALYLLWVNVLGPWFTADSGTPAPEHNEKRQRRQERRQMKRL
Function: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 19642 Sequence Length: 173 Subcellular Location: Endoplasmic reticulum membrane
Q9NX78
MSPHGDGRGQAQGRAVRVGLRRSGGIRGGVAVFAAVAAVFTFTLPPSVPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAITLFPFGSIAYRVNLLCGLFGAVAASLLFFTVFRLSGSSAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAKERSKVAKIGAFCCGLSLCNQHTIILYVLCIIPWILFQLLKKKELSLGSLLKLSLYFSAGLLPYVHLPISSYLNHARWTWGDQTTLQGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTELSFNIQALAVCANICLATKDRQNPS...
Function: O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins . Specifically glycosylates the IPT/TIG domain of target proteins, such as MET and MST1R/RON . TMEM260-mediated O-mannosylated residues are composed of single mannose glycans that are not ...
E9PQX1
MWLQDRIATFFFPKGMMLTTAALMLFFLHLGIFIRDVHNFCITYHYDHMSFHYTVVLMFSQVISICWAAMGSLYAEMTENKYVCFSALTILMLNGAMFFNRLSLEFLAIEYREEHH
Function: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 13758 Sequence Length: 116 Subcellular Location: Cell projection
Q3SYV1
MNQTDKNQQEIPSYLSDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLTGKKKDKSD
Function: May play a role in bone development. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 11721 Sequence Length: 116 Subcellular Location: Membrane
Q5ZLA9
MNQTDKSHQEVPSYLHDEPPEGSIKDHPQQQPSMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEITKTAVTSVPSMGVGLVKGSVSAVAGGVTAVGSAVASKVPLTGKKKDKSD
Function: May be involved in the growth pathway. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 11712 Sequence Length: 116 Subcellular Location: Membrane
Q8WUH6
MNQTDKNQQEIPSYLNDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLTGKKKDKSD
Function: May play a role in bone development. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 11748 Sequence Length: 116 Subcellular Location: Membrane
Q2M3C6
MAVAPSFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAGTWDEETAAESVVEELQPSQE...
Function: Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum . Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear . Undergoes both rapid and slow structural rearrangements i...
Q8BZB3
MALVTSFNMANPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTGGSQLLSNLDEEYQREGSDWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDTKLLQFSNAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDAYVLPVKLEMEMVTQQYEKAKAIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESIVEELRPSQE...
Function: Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear. Undergoes both rapid and slow structural rearrangements in ...
Q6UXY8
MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYV...
Function: Probable ion channel. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 114797 Sequence Length: 1006 Subcellular Location: Membrane
Q7Z403
MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCG...
Function: Probable ion channel. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 90045 Sequence Length: 805 Subcellular Location: Endoplasmic reticulum membrane
Q7TN60
MAQSLALALDVPETTGDEGLEPSPYEESEVHDSFHQLIQEQSLRVAEEGLELLPLGLGRGDQTLPGLEGAPALSSATLRILASMPSRTIGRSRGAIISQYYNRTVRLRRRSSRPLLGNVVPSARPSLRLYDLELDSTILEEDEKRSLLVKELQGLSAAQRDHMVRNMPLSLGEKRCLREKSWSPKGKRRHLQGRSGAFSCCSRLRYTCMLALHSLGLALLSGLYAARPWRYALKQIGGQFGSSVLSYFLFLKTLLAFNALMLLPLLAFLVGVQAAFPPDPAGPVPTFSGLELLTGGGRFTHTVMYYGYYSNSTLSPSCDA...
Function: Probable ion channel. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 90546 Sequence Length: 810 Subcellular Location: Endoplasmic reticulum membrane
Q5YCC5
MSEFGAGAELPGWVTESRSRGEFFSPEESHAAAPAGFLQELPSYRSVLWRRAAAGDVQERWGNLRGIASAERREPQPDGGERGAIPLWELPFSIAEKRDSQQGDIKYSSGWNHWKRTSSKSWKKALKDIKELSSYMQLWRHDIHSIEGKFGTGIQSYFSFLRFLVLLNFLMFILMFSFVTLPAVISNYGIFNSSSTKISPNNTEPYCTVYTPSGNKGLVYFYTYLKDLLTGTGFLEVTVLFYGYYTIDAAWFSVLRYNLPLAYLLTTFAYLALSFVWIIKRSVERFRQHLVDDEDQFQSYCNKVFAGWDFCITDLNAARL...
Function: Probable ion channel. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 84377 Sequence Length: 735 Subcellular Location: Membrane
Q7Z402
MSESSGSALQPGRPSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSRDKQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNR...
Function: Probable ion channel. Location Topology: Multi-pass membrane protein Sequence Mass (Da): 83502 Sequence Length: 723 Subcellular Location: Membrane