| <table border="1"> | |
| <tr><td>Rank</td><td>Lane</td><td>Name</td><td>Nationality</td><td>Time</td><td>Notes</td></tr> | |
| <tr><td>-</td><td>4</td><td>Katinka Hosszú</td><td>Hungary</td><td>4:26.36</td><td>WR</td></tr> | |
| <tr><td>-</td><td>3</td><td>Maya DiRado</td><td>United States</td><td>4:31.15</td><td>-</td></tr> | |
| <tr><td>-</td><td>5</td><td>Mireia Belmonte</td><td>Spain</td><td>4:32.39</td><td>-</td></tr> | |
| <tr><td>4</td><td>6</td><td>Hannah Miley</td><td>Great Britain</td><td>4:32.54</td><td>-</td></tr> | |
| <tr><td>5</td><td>8</td><td>Emily Overholt</td><td>Canada</td><td>4:34.70</td><td>-</td></tr> | |
| <tr><td>6</td><td>7</td><td>Elizabeth Beisel</td><td>United States</td><td>4:34.98</td><td>-</td></tr> | |
| <tr><td>7</td><td>2</td><td>Aimee Willmott</td><td>Great Britain</td><td>4:35.04</td><td>-</td></tr> | |
| <tr><td>8</td><td>1</td><td>Sakiko Shimizu</td><td>Japan</td><td>4:38.06</td><td>-</td></tr> | |
| </table> | |