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The weighted-average fair value of the options granted under all equity incentive plans during the years ended December 31, 2024 and 2023 was $ 1.49 and $ 1.96 per share, respectively, applying the Black-Scholes-Merton option pricing model utilizing the following weighted-average assumptions:
text
1.96
perShareItemType
text: <entity> 1.96 </entity> <entity type> perShareItemType </entity type> <context> The weighted-average fair value of the options granted under all equity incentive plans during the years ended December 31, 2024 and 2023 was $ 1.49 and $ 1.96 per share, respectively, applying the Black-Scholes-Merton option pricing model utilizing the following weighted-average assumptions: </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited.
text
351.8
monetaryItemType
text: <entity> 351.8 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited. </context>
us-gaap:OperatingLossCarryforwards
As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited.
text
10.9
monetaryItemType
text: <entity> 10.9 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited. </context>
us-gaap:TaxCreditCarryforwardAmount
As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited.
text
44.1
monetaryItemType
text: <entity> 44.1 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2024, the Company had $ 351.8 million of U.S. Federal and state net operating losses, $ 10.9 million of research and development tax credits and $ 44.1 million of orphan drug tax credits available to carry forward. A portion of the net operating loss carryforwards will begin to expire in 2025, the research and development tax credits in 2025 and the orphan drug tax credit in 2033. Under current federal income tax laws, federal net operating losses incurred in 2018 and in future years may be carried forward indefinitely, but the deductibility of such federal net operating losses is limited. </context>
us-gaap:TaxCreditCarryforwardAmount
The Company has a defined contribution plan under the Internal Revenue Code Section 401(k). This plan covers substantially all employees who meet minimum age and service requirements and allows participants to defer a portion of their annual compensation on a pre-tax basis. For the years ended December 31, 2024, 2023 and 2022, the Company matched 50 % up to the first 6 % of employee contributions. All matching contributions have been paid by the Company. The Company’s matching contributions vest in full immediately. The total Company matching contributions were approximately $ 211,000 and $ 248,000 for the years ended December 31, 2024 and 2023, respectively.
text
211000
monetaryItemType
text: <entity> 211000 </entity> <entity type> monetaryItemType </entity type> <context> The Company has a defined contribution plan under the Internal Revenue Code Section 401(k). This plan covers substantially all employees who meet minimum age and service requirements and allows participants to defer a portion of their annual compensation on a pre-tax basis. For the years ended December 31, 2024, 2023 and 2022, the Company matched 50 % up to the first 6 % of employee contributions. All matching contributions have been paid by the Company. The Company’s matching contributions vest in full immediately. The total Company matching contributions were approximately $ 211,000 and $ 248,000 for the years ended December 31, 2024 and 2023, respectively. </context>
us-gaap:DefinedContributionPlanEmployerDiscretionaryContributionAmount
The Company has a defined contribution plan under the Internal Revenue Code Section 401(k). This plan covers substantially all employees who meet minimum age and service requirements and allows participants to defer a portion of their annual compensation on a pre-tax basis. For the years ended December 31, 2024, 2023 and 2022, the Company matched 50 % up to the first 6 % of employee contributions. All matching contributions have been paid by the Company. The Company’s matching contributions vest in full immediately. The total Company matching contributions were approximately $ 211,000 and $ 248,000 for the years ended December 31, 2024 and 2023, respectively.
text
248000
monetaryItemType
text: <entity> 248000 </entity> <entity type> monetaryItemType </entity type> <context> The Company has a defined contribution plan under the Internal Revenue Code Section 401(k). This plan covers substantially all employees who meet minimum age and service requirements and allows participants to defer a portion of their annual compensation on a pre-tax basis. For the years ended December 31, 2024, 2023 and 2022, the Company matched 50 % up to the first 6 % of employee contributions. All matching contributions have been paid by the Company. The Company’s matching contributions vest in full immediately. The total Company matching contributions were approximately $ 211,000 and $ 248,000 for the years ended December 31, 2024 and 2023, respectively. </context>
us-gaap:DefinedContributionPlanEmployerDiscretionaryContributionAmount
In July 2024, the Company’s Board of Directors approved a streamlined operating plan that included a reduction in the Company’s workforce by 26 employees, or approximately 80 % of its headcount.
text
26
integerItemType
text: <entity> 26 </entity> <entity type> integerItemType </entity type> <context> In July 2024, the Company’s Board of Directors approved a streamlined operating plan that included a reduction in the Company’s workforce by 26 employees, or approximately 80 % of its headcount. </context>
us-gaap:RestructuringAndRelatedCostNumberOfPositionsEliminated
In July 2024, the Company’s Board of Directors approved a streamlined operating plan that included a reduction in the Company’s workforce by 26 employees, or approximately 80 % of its headcount.
text
80
percentItemType
text: <entity> 80 </entity> <entity type> percentItemType </entity type> <context> In July 2024, the Company’s Board of Directors approved a streamlined operating plan that included a reduction in the Company’s workforce by 26 employees, or approximately 80 % of its headcount. </context>
us-gaap:RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
Employees affected by the reduction in force are entitled to receive severance payments and Company-funded medical insurance for a specific time. During the year ended December 31, 2024, the Company recognized $ 7.0 million of charges for severance and related benefits.
text
7.0
monetaryItemType
text: <entity> 7.0 </entity> <entity type> monetaryItemType </entity type> <context> Employees affected by the reduction in force are entitled to receive severance payments and Company-funded medical insurance for a specific time. During the year ended December 31, 2024, the Company recognized $ 7.0 million of charges for severance and related benefits. </context>
us-gaap:RestructuringCharges
The accrued severance liability of $ 3.5 million is payable within the next twelve months and has been included in accrued expenses on the balance sheet as of December 31, 2024.
text
3.5
monetaryItemType
text: <entity> 3.5 </entity> <entity type> monetaryItemType </entity type> <context> The accrued severance liability of $ 3.5 million is payable within the next twelve months and has been included in accrued expenses on the balance sheet as of December 31, 2024. </context>
us-gaap:PaymentsForRestructuring
The Company recorded $ 0.4 million of impairment charges related to its facility operating lease and accelerated depreciation on property and equipment during the year ended December 31, 2024.
text
0.4
monetaryItemType
text: <entity> 0.4 </entity> <entity type> monetaryItemType </entity type> <context> The Company recorded $ 0.4 million of impairment charges related to its facility operating lease and accelerated depreciation on property and equipment during the year ended December 31, 2024. </context>
us-gaap:RestructuringReserveAcceleratedDepreciation
Accrued interest receivables on debt securities available-for-sale were $ 11.2 million and $ 4.7 million, respectively, as of December 31, 2023 and 2022. We do not measure an allowance for credit losses for accrued interest receivables. For the purposes of identifying and measuring an impairment, accrued interest is excluded from both the fair value and amortized cost basis of the debt security. Uncollectible accrued interest receivables associated with an impaired debt security are reversed against interest income upon identification of the impairment. No accrued interest receivables were written off during 2023, 2022 or 2021.
text
11.2
monetaryItemType
text: <entity> 11.2 </entity> <entity type> monetaryItemType </entity type> <context> Accrued interest receivables on debt securities available-for-sale were $ 11.2 million and $ 4.7 million, respectively, as of December 31, 2023 and 2022. We do not measure an allowance for credit losses for accrued interest receivables. For the purposes of identifying and measuring an impairment, accrued interest is excluded from both the fair value and amortized cost basis of the debt security. Uncollectible accrued interest receivables associated with an impaired debt security are reversed against interest income upon identification of the impairment. No accrued interest receivables were written off during 2023, 2022 or 2021. </context>
us-gaap:InterestReceivableCurrent
Accrued interest receivables on debt securities available-for-sale were $ 11.2 million and $ 4.7 million, respectively, as of December 31, 2023 and 2022. We do not measure an allowance for credit losses for accrued interest receivables. For the purposes of identifying and measuring an impairment, accrued interest is excluded from both the fair value and amortized cost basis of the debt security. Uncollectible accrued interest receivables associated with an impaired debt security are reversed against interest income upon identification of the impairment. No accrued interest receivables were written off during 2023, 2022 or 2021.
text
4.7
monetaryItemType
text: <entity> 4.7 </entity> <entity type> monetaryItemType </entity type> <context> Accrued interest receivables on debt securities available-for-sale were $ 11.2 million and $ 4.7 million, respectively, as of December 31, 2023 and 2022. We do not measure an allowance for credit losses for accrued interest receivables. For the purposes of identifying and measuring an impairment, accrued interest is excluded from both the fair value and amortized cost basis of the debt security. Uncollectible accrued interest receivables associated with an impaired debt security are reversed against interest income upon identification of the impairment. No accrued interest receivables were written off during 2023, 2022 or 2021. </context>
us-gaap:InterestReceivableCurrent
Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021.
text
17.8
monetaryItemType
text: <entity> 17.8 </entity> <entity type> monetaryItemType </entity type> <context> Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021. </context>
us-gaap:Depreciation
Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021.
text
15.1
monetaryItemType
text: <entity> 15.1 </entity> <entity type> monetaryItemType </entity type> <context> Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021. </context>
us-gaap:Depreciation
Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021.
text
10.9
monetaryItemType
text: <entity> 10.9 </entity> <entity type> monetaryItemType </entity type> <context> Property and equipment are stated at cost and depreciated over the estimated useful lives of the assets using the straight-line method. Equipment is depreciated over an average estimated useful life of 3 to 7 years. Leasehold improvements are depreciated over the shorter of their estimated useful lives or the remaining lease term. Depreciation expense was $ 17.8 million for 2023, $ 15.1 million for 2022 and $ 10.9 million for 2021. </context>
us-gaap:Depreciation
We have entered into agreements for the distribution of INGREZZA with a limited number of specialty pharmacy providers and distributors and all of our product sales of INGREZZA are to these customers. Four of these customers represented approximately 91 % of our total product sales for 2023 and approximately 98 % of our accounts receivable balance as of December 31, 2023.
text
91
percentItemType
text: <entity> 91 </entity> <entity type> percentItemType </entity type> <context> We have entered into agreements for the distribution of INGREZZA with a limited number of specialty pharmacy providers and distributors and all of our product sales of INGREZZA are to these customers. Four of these customers represented approximately 91 % of our total product sales for 2023 and approximately 98 % of our accounts receivable balance as of December 31, 2023. </context>
us-gaap:ConcentrationRiskPercentage1
We have entered into agreements for the distribution of INGREZZA with a limited number of specialty pharmacy providers and distributors and all of our product sales of INGREZZA are to these customers. Four of these customers represented approximately 91 % of our total product sales for 2023 and approximately 98 % of our accounts receivable balance as of December 31, 2023.
text
98
percentItemType
text: <entity> 98 </entity> <entity type> percentItemType </entity type> <context> We have entered into agreements for the distribution of INGREZZA with a limited number of specialty pharmacy providers and distributors and all of our product sales of INGREZZA are to these customers. Four of these customers represented approximately 91 % of our total product sales for 2023 and approximately 98 % of our accounts receivable balance as of December 31, 2023. </context>
us-gaap:ConcentrationRiskPercentage1
Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021.
text
159.9
monetaryItemType
text: <entity> 159.9 </entity> <entity type> monetaryItemType </entity type> <context> Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021. </context>
us-gaap:AdvertisingExpense
Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021.
text
149.7
monetaryItemType
text: <entity> 149.7 </entity> <entity type> monetaryItemType </entity type> <context> Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021. </context>
us-gaap:AdvertisingExpense
Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021.
text
139.8
monetaryItemType
text: <entity> 139.8 </entity> <entity type> monetaryItemType </entity type> <context> Advertising costs are expensed as selling, general and administrative when incurred. Advertising expense was $ 159.9 million for 2023, $ 149.7 million for 2022 and $ 139.8 million for 2021. </context>
us-gaap:AdvertisingExpense
In 2021, we entered into the First Supplemental Indenture to the 2017 Indenture, pursuant to which we irrevocably elected to settle the principal amount of the 2.25 % fixed-rate convertible senior notes due May 15, 2024 in cash upon conversion and to settle any conversion premium in either cash or shares of our common stock. As a result, only the shares required to settle any conversion premium are considered dilutive under the if-converted method. Further, PRSUs for which the performance condition has not been achieved are excluded from the calculation of diluted earnings per share.
text
2.25
percentItemType
text: <entity> 2.25 </entity> <entity type> percentItemType </entity type> <context> In 2021, we entered into the First Supplemental Indenture to the 2017 Indenture, pursuant to which we irrevocably elected to settle the principal amount of the 2.25 % fixed-rate convertible senior notes due May 15, 2024 in cash upon conversion and to settle any conversion premium in either cash or shares of our common stock. As a result, only the shares required to settle any conversion premium are considered dilutive under the if-converted method. Further, PRSUs for which the performance condition has not been achieved are excluded from the calculation of diluted earnings per share. </context>
us-gaap:DebtInstrumentInterestRateStatedPercentage
In connection with the agreement, we paid Heptares $ 100.0 million upfront, which, including certain transaction-related costs, was expensed as IPR&D in 2021 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business.
text
100.0
monetaryItemType
text: <entity> 100.0 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the agreement, we paid Heptares $ 100.0 million upfront, which, including certain transaction-related costs, was expensed as IPR&D in 2021 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. </context>
us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
In connection with the FDA's acceptance of our investigational new drug application for NBI-1117568 for the treatment of schizophrenia in June 2022, we paid Heptares a milestone of $ 30.0 million, which was expensed as R&D in 2022.
text
30.0
monetaryItemType
text: <entity> 30.0 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the FDA's acceptance of our investigational new drug application for NBI-1117568 for the treatment of schizophrenia in June 2022, we paid Heptares a milestone of $ 30.0 million, which was expensed as R&D in 2022. </context>
us-gaap:ResearchAndDevelopmentExpense
In connection with the approval of our clinical trial application for NBI-1070770 for the treatment of major depressive disorder in 2022, we paid Takeda a milestone of $ 5.0 million, which was expensed as R&D in 2022.
text
5.0
monetaryItemType
text: <entity> 5.0 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the approval of our clinical trial application for NBI-1070770 for the treatment of major depressive disorder in 2022, we paid Takeda a milestone of $ 5.0 million, which was expensed as R&D in 2022. </context>
us-gaap:ResearchAndDevelopmentExpense
In connection with the agreement, we purchased approximately 1.4 million shares (at $ 14.196 per share) of Xenon common stock in 2019. The purchased shares were recorded at a fair value of $ 14.1 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date.
text
14.196
perShareItemType
text: <entity> 14.196 </entity> <entity type> perShareItemType </entity type> <context> In connection with the agreement, we purchased approximately 1.4 million shares (at $ 14.196 per share) of Xenon common stock in 2019. The purchased shares were recorded at a fair value of $ 14.1 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. </context>
us-gaap:SharePrice
In connection with the agreement, we purchased approximately 1.4 million shares (at $ 14.196 per share) of Xenon common stock in 2019. The purchased shares were recorded at a fair value of $ 14.1 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date.
text
14.1
monetaryItemType
text: <entity> 14.1 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the agreement, we purchased approximately 1.4 million shares (at $ 14.196 per share) of Xenon common stock in 2019. The purchased shares were recorded at a fair value of $ 14.1 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. </context>
us-gaap:EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue
In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021.
text
19.9755
perShareItemType
text: <entity> 19.9755 </entity> <entity type> perShareItemType </entity type> <context> In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021. </context>
us-gaap:SharePrice
In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021.
text
4.6
monetaryItemType
text: <entity> 4.6 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021. </context>
us-gaap:EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue
In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021.
text
5.4
monetaryItemType
text: <entity> 5.4 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the regulatory approval of our clinical trial application in Europe for NBI-921352 for the treatment of focal onset seizures in adults in 2021, we paid Xenon a regulatory milestone of $ 10.0 million, including a purchase of approximately 0.3 million shares (at $ 19.9755 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 4.6 million after considering Xenon’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. The remaining $ 5.4 million of the milestone payment was expensed as R&D in 2021. </context>
us-gaap:ResearchAndDevelopmentExpense
study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022.
text
31.855
perShareItemType
text: <entity> 31.855 </entity> <entity type> perShareItemType </entity type> <context> study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022. </context>
us-gaap:SharePrice
study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022.
text
7.7
monetaryItemType
text: <entity> 7.7 </entity> <entity type> monetaryItemType </entity type> <context> study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022. </context>
us-gaap:EquitySecuritiesFvNiCost
study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022.
text
7.3
monetaryItemType
text: <entity> 7.3 </entity> <entity type> monetaryItemType </entity type> <context> study protocol in 2022, we paid Xenon a regulatory milestone of $ 15.0 million, including a purchase of approximately 0.3 million shares (at $ 31.855 per share) of Xenon common stock. The purchased shares were recorded at a fair value of $ 7.7 million after considering Xenon’s stock price on the measurement date. The remaining $ 7.3 million of the milestone payment was expensed as R&D in 2022. </context>
us-gaap:ResearchAndDevelopmentExpense
In connection with the 2019 Voyager Agreement, we purchased approximately 4.2 million shares (at $ 11.9625 per share) of Voyager common stock (the 2019 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement (defined below). The 2019 Purchased Shares were recorded at a fair value of $ 54.7 million after considering Voyager’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date.
text
11.9625
perShareItemType
text: <entity> 11.9625 </entity> <entity type> perShareItemType </entity type> <context> In connection with the 2019 Voyager Agreement, we purchased approximately 4.2 million shares (at $ 11.9625 per share) of Voyager common stock (the 2019 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement (defined below). The 2019 Purchased Shares were recorded at a fair value of $ 54.7 million after considering Voyager’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. </context>
us-gaap:SharePrice
In connection with the 2019 Voyager Agreement, we purchased approximately 4.2 million shares (at $ 11.9625 per share) of Voyager common stock (the 2019 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement (defined below). The 2019 Purchased Shares were recorded at a fair value of $ 54.7 million after considering Voyager’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date.
text
54.7
monetaryItemType
text: <entity> 54.7 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2019 Voyager Agreement, we purchased approximately 4.2 million shares (at $ 11.9625 per share) of Voyager common stock (the 2019 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement (defined below). The 2019 Purchased Shares were recorded at a fair value of $ 54.7 million after considering Voyager’s stock price and certain transfer restrictions that were applicable to the shares on the measurement date. </context>
us-gaap:EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
8.88
perShareItemType
text: <entity> 8.88 </entity> <entity type> perShareItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:SharePrice
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
19.9
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text: <entity> 19.9 </entity> <entity type> percentItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquityMethodInvestmentOwnershipPercentage
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
31.3
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text: <entity> 31.3 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquitySecuritiesFvNiCost
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
143.9
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text: <entity> 143.9 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
15.5
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text: <entity> 15.5 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
14.5
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text: <entity> 14.5 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
8.7
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text: <entity> 8.7 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquitySecuritiesFvNiUnrealizedGainLoss
In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million.
text
72.4
monetaryItemType
text: <entity> 72.4 </entity> <entity type> monetaryItemType </entity type> <context> In connection with the 2023 Voyager Agreement, we paid Voyager $ 175.0 million upfront, including a purchase of approximately 4.4 million shares (at $ 8.88 per share) of Voyager common stock (the 2023 Purchased Shares), which are subject to certain transfer, beneficial ownership, and voting restrictions for a period of up to three years from the effective date of the 2023 Voyager Agreement. In addition, as part of the collaboration, Jude Onyia, Ph.D., Chief Scientific Officer of Neurocrine, was appointed to Voyager's board of directors with an initial term expiring in 2024. Mr. Onyia (or another individual designated by us) will be nominated for election to Voyager's board of directors annually for a maximum duration of 10 years from the effective date of the 2023 Voyager Agreement. As a result, our strategic investment in Voyager became subject to the equity method of accounting, and Voyager became a related party under ASC 850, following our purchase of the 2023 Purchased Shares, after which, together with the 2019 Purchased Shares, we owned approximately 19.9 % of the voting stock of Voyager. We elected the fair value option to account for our strategic investment in Voyager as we believe it creates greater transparency regarding the investment's fair value at future reporting dates. The 2023 Purchased Shares were recorded at a fair value of $ 31.3 million after considering Voyager’s stock price on the measurement date. The remaining $ 143.9 million of the purchase price, which includes certain transaction-related costs, was expensed as IPR&D in 2023 as the license had no foreseeable alternative future use. We accounted for the transaction as an asset acquisition as the set of acquired assets did not constitute a business. We recognized unrealized gains of $ 15.5 million for 2023 and $ 14.5 million for 2022 and an unrealized loss of $ 8.7 million for 2021 on our strategic investment in Voyager. As of December 31, 2023, the fair value (Level 1) of our strategic investment in Voyager was $ 72.4 million. </context>
us-gaap:EquitySecuritiesFvNiCurrentAndNoncurrent
(opicapone) in the U.S. and Canada. We launched ONGENTYS in the U.S. as an FDA-approved add-on treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing motor fluctuations in 2020. In 2023, we provided BIAL with written notice of termination of the license agreement to commercialize and market ONGENTYS in the U.S. and Canada, and recognized reserves for ONGENTYS inventory obsolescence totaling $ 5.2 million in cost of revenues in connection with the termination, which became effective in December 2023, as management determined the cost cannot be recovered.
text
5.2
monetaryItemType
text: <entity> 5.2 </entity> <entity type> monetaryItemType </entity type> <context> (opicapone) in the U.S. and Canada. We launched ONGENTYS in the U.S. as an FDA-approved add-on treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing motor fluctuations in 2020. In 2023, we provided BIAL with written notice of termination of the license agreement to commercialize and market ONGENTYS in the U.S. and Canada, and recognized reserves for ONGENTYS inventory obsolescence totaling $ 5.2 million in cost of revenues in connection with the termination, which became effective in December 2023, as management determined the cost cannot be recovered. </context>
us-gaap:InventoryValuationReserves
(valbenazine). We receive royalties at tiered percentage rates on MTPC net sales of valbenazine. In connection with MTPC's first commercial sale of DYSVAL in Japan, we received a milestone payment of $ 20.0 million in 2022. ASC 606 provides a royalty exception for a sales-based or usage-based royalty promised in exchange for a license of intellectual property. Under the royalty exception, the milestone would be recognized as revenue only when the later of (1) the subsequent sale or usage occurs or (2) the performance obligation to which some or all of the sales-based or usage-based royalty has been allocated has been satisfied (or partially satisfied). As the milestone related to a license of intellectual property and was contingent upon MTPC’s first commercial sale of DYSVAL in Japan, the milestone was recognized as revenue in 2022.
text
20.0
monetaryItemType
text: <entity> 20.0 </entity> <entity type> monetaryItemType </entity type> <context> (valbenazine). We receive royalties at tiered percentage rates on MTPC net sales of valbenazine. In connection with MTPC's first commercial sale of DYSVAL in Japan, we received a milestone payment of $ 20.0 million in 2022. ASC 606 provides a royalty exception for a sales-based or usage-based royalty promised in exchange for a license of intellectual property. Under the royalty exception, the milestone would be recognized as revenue only when the later of (1) the subsequent sale or usage occurs or (2) the performance obligation to which some or all of the sales-based or usage-based royalty has been allocated has been satisfied (or partially satisfied). As the milestone related to a license of intellectual property and was contingent upon MTPC’s first commercial sale of DYSVAL in Japan, the milestone was recognized as revenue in 2022. </context>
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
(elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021.
text
16.7
monetaryItemType
text: <entity> 16.7 </entity> <entity type> monetaryItemType </entity type> <context> (elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021. </context>
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
(elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021.
text
21.2
monetaryItemType
text: <entity> 21.2 </entity> <entity type> monetaryItemType </entity type> <context> (elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021. </context>
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
(elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021.
text
22.3
monetaryItemType
text: <entity> 22.3 </entity> <entity type> monetaryItemType </entity type> <context> (elagolix, estradiol and norethindrone acetate capsules and elagolix capsules) in the U.S. for the treatment of heavy menstrual bleeding due to uterine fibroids in June 2020. We receive royalties at tiered percentage rates on AbbVie net sales of elagolix and recognized elagolix royalty revenue of $ 16.7 million for 2023, $ 21.2 million for 2022 and $ 22.3 million for 2021. </context>
us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax
On May 2, 2017, we completed a private placement of $ 517.5 million in aggregate principal amount of 2.25 % fixed-rate convertible senior notes due May 15, 2024 (the 2024 Notes) and entered into the 2017 Indenture with respect to the 2024 Notes. Interest on the 2024 Notes is due semi-annually on May 15 and November 15 of each year.
text
517.5
monetaryItemType
text: <entity> 517.5 </entity> <entity type> monetaryItemType </entity type> <context> On May 2, 2017, we completed a private placement of $ 517.5 million in aggregate principal amount of 2.25 % fixed-rate convertible senior notes due May 15, 2024 (the 2024 Notes) and entered into the 2017 Indenture with respect to the 2024 Notes. Interest on the 2024 Notes is due semi-annually on May 15 and November 15 of each year. </context>
us-gaap:DebtInstrumentFaceAmount
On May 2, 2017, we completed a private placement of $ 517.5 million in aggregate principal amount of 2.25 % fixed-rate convertible senior notes due May 15, 2024 (the 2024 Notes) and entered into the 2017 Indenture with respect to the 2024 Notes. Interest on the 2024 Notes is due semi-annually on May 15 and November 15 of each year.
text
2.25
percentItemType
text: <entity> 2.25 </entity> <entity type> percentItemType </entity type> <context> On May 2, 2017, we completed a private placement of $ 517.5 million in aggregate principal amount of 2.25 % fixed-rate convertible senior notes due May 15, 2024 (the 2024 Notes) and entered into the 2017 Indenture with respect to the 2024 Notes. Interest on the 2024 Notes is due semi-annually on May 15 and November 15 of each year. </context>
us-gaap:DebtInstrumentInterestRateStatedPercentage
In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment.
text
136.2
monetaryItemType
text: <entity> 136.2 </entity> <entity type> monetaryItemType </entity type> <context> In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment. </context>
us-gaap:DebtInstrumentRepurchasedFaceAmount
In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment.
text
186.9
monetaryItemType
text: <entity> 186.9 </entity> <entity type> monetaryItemType </entity type> <context> In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment. </context>
us-gaap:RepaymentsOfDebt
In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment.
text
210.8
monetaryItemType
text: <entity> 210.8 </entity> <entity type> monetaryItemType </entity type> <context> In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment. </context>
us-gaap:DebtInstrumentRepurchasedFaceAmount
In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment.
text
279.0
monetaryItemType
text: <entity> 279.0 </entity> <entity type> monetaryItemType </entity type> <context> In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment. </context>
us-gaap:RepaymentsOfDebt
In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment.
text
70.0
monetaryItemType
text: <entity> 70.0 </entity> <entity type> monetaryItemType </entity type> <context> In 2020, we repurchased $ 136.2 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 186.9 million in cash. In 2022, we repurchased $ 210.8 million aggregate principal amount of the 2024 Notes for an aggregate repurchase price of $ 279.0 million in cash, which resulted in the recognition of a $ 70.0 million loss on extinguishment. </context>
us-gaap:GainsLossesOnExtinguishmentOfDebt
The initial conversion rate for the 2024 Notes, which is subject to adjustment in some events (as provided for in the 2017 Indenture), is 13.1711 shares of common stock per $ 1,000 principal amount and equivalent to an initial conversion price of approximately $ 75.92 per share, reflecting a conversion premium of approximately 42.5 % above the closing price of $ 53.28 per share of our common stock on April 26, 2017.
text
75.92
perShareItemType
text: <entity> 75.92 </entity> <entity type> perShareItemType </entity type> <context> The initial conversion rate for the 2024 Notes, which is subject to adjustment in some events (as provided for in the 2017 Indenture), is 13.1711 shares of common stock per $ 1,000 principal amount and equivalent to an initial conversion price of approximately $ 75.92 per share, reflecting a conversion premium of approximately 42.5 % above the closing price of $ 53.28 per share of our common stock on April 26, 2017. </context>
us-gaap:DebtInstrumentConvertibleConversionPrice1
The initial conversion rate for the 2024 Notes, which is subject to adjustment in some events (as provided for in the 2017 Indenture), is 13.1711 shares of common stock per $ 1,000 principal amount and equivalent to an initial conversion price of approximately $ 75.92 per share, reflecting a conversion premium of approximately 42.5 % above the closing price of $ 53.28 per share of our common stock on April 26, 2017.
text
53.28
perShareItemType
text: <entity> 53.28 </entity> <entity type> perShareItemType </entity type> <context> The initial conversion rate for the 2024 Notes, which is subject to adjustment in some events (as provided for in the 2017 Indenture), is 13.1711 shares of common stock per $ 1,000 principal amount and equivalent to an initial conversion price of approximately $ 75.92 per share, reflecting a conversion premium of approximately 42.5 % above the closing price of $ 53.28 per share of our common stock on April 26, 2017. </context>
us-gaap:SharePrice
We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption.
text
130
percentItemType
text: <entity> 130 </entity> <entity type> percentItemType </entity type> <context> We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption. </context>
us-gaap:DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger
We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption.
text
98.70
perShareItemType
text: <entity> 98.70 </entity> <entity type> perShareItemType </entity type> <context> We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption. </context>
us-gaap:DebtInstrumentConvertibleStockPriceTrigger
We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption.
text
20
integerItemType
text: <entity> 20 </entity> <entity type> integerItemType </entity type> <context> We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption. </context>
us-gaap:DebtInstrumentConvertibleThresholdTradingDays
We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption.
text
30
integerItemType
text: <entity> 30 </entity> <entity type> integerItemType </entity type> <context> We may redeem for cash all or part of the 2024 Notes if the last reported sale price (as defined in the 2017 Indenture) of our common stock has been at least 130 % of the conversion price then in effect (equal to $ 98.70 as of December 31, 2023) for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period ending on, and including, the trading day immediately before the date which we provide notice of redemption. </context>
us-gaap:DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day;
text
20
integerItemType
text: <entity> 20 </entity> <entity type> integerItemType </entity type> <context> during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day; </context>
us-gaap:DebtInstrumentConvertibleThresholdTradingDays
during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day;
text
30
integerItemType
text: <entity> 30 </entity> <entity type> integerItemType </entity type> <context> during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day; </context>
us-gaap:DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day;
text
130
percentItemType
text: <entity> 130 </entity> <entity type> percentItemType </entity type> <context> during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day; </context>
us-gaap:DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger
during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day;
text
98.70
perShareItemType
text: <entity> 98.70 </entity> <entity type> perShareItemType </entity type> <context> during any calendar quarter (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than 130 % of the conversion price (equal to $ 98.70 as of December 31, 2023) on each applicable trading day; </context>
us-gaap:DebtInstrumentConvertibleStockPriceTrigger
Until the close of business on the scheduled trading day immediately preceding May 15, 2024, holders of the 2024 Notes may convert the 2024 Notes at any time. On January 4, 2024, we provided notice to the holders of the 2024 Notes electing to settle all conversions of the 2024 Notes in cash. As such, upon conversion, holders will receive the principal amount of their 2024 Notes and any conversion premium, calculated based on the per share volume-weighted average price for each of the 30 consecutive trading days during the observation period (as more fully described in the 2017 Indenture), in cash.
text
30
integerItemType
text: <entity> 30 </entity> <entity type> integerItemType </entity type> <context> Until the close of business on the scheduled trading day immediately preceding May 15, 2024, holders of the 2024 Notes may convert the 2024 Notes at any time. On January 4, 2024, we provided notice to the holders of the 2024 Notes electing to settle all conversions of the 2024 Notes in cash. As such, upon conversion, holders will receive the principal amount of their 2024 Notes and any conversion premium, calculated based on the per share volume-weighted average price for each of the 30 consecutive trading days during the observation period (as more fully described in the 2017 Indenture), in cash. </context>
us-gaap:DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
If we undergo a fundamental change (as defined in the 2017 Indenture), subject to certain conditions, holders of the 2024 Notes may require us to repurchase for cash all or part of their 2024 Notes at a repurchase price equal to 100 % of the principal amount of the 2024 Notes to be repurchased, plus accrued and unpaid interest to, but excluding, the fundamental change repurchase date. In addition, if a make-whole fundamental change (as defined in the 2017 Indenture) occurs prior to January 15, 2024, we would, in certain circumstances, increase the conversion rate for a holder who elects to convert their notes in connection with the make-whole fundamental change.
text
100
percentItemType
text: <entity> 100 </entity> <entity type> percentItemType </entity type> <context> If we undergo a fundamental change (as defined in the 2017 Indenture), subject to certain conditions, holders of the 2024 Notes may require us to repurchase for cash all or part of their 2024 Notes at a repurchase price equal to 100 % of the principal amount of the 2024 Notes to be repurchased, plus accrued and unpaid interest to, but excluding, the fundamental change repurchase date. In addition, if a make-whole fundamental change (as defined in the 2017 Indenture) occurs prior to January 15, 2024, we would, in certain circumstances, increase the conversion rate for a holder who elects to convert their notes in connection with the make-whole fundamental change. </context>
us-gaap:DebtInstrumentRedemptionPricePercentageOfPrincipalAmountRedeemed
The 2024 Notes are our general unsecured obligations that rank senior in right of payment to all of our indebtedness that is expressly subordinated in right of payment to the 2024 Notes, and equal in right of payment to our unsecured indebtedness. The 2024 Notes do not contain any financial or operating covenants or any restrictions on the payment of dividends, the issuance of other indebtedness or the issuance or repurchase of securities by us. The 2017 Indenture contains customary events of default with respect to the 2024 Notes, including that upon certain events of default, 100 % of the principal and accrued and unpaid interest on the 2024 Notes will automatically become due and payable.
text
100
percentItemType
text: <entity> 100 </entity> <entity type> percentItemType </entity type> <context> The 2024 Notes are our general unsecured obligations that rank senior in right of payment to all of our indebtedness that is expressly subordinated in right of payment to the 2024 Notes, and equal in right of payment to our unsecured indebtedness. The 2024 Notes do not contain any financial or operating covenants or any restrictions on the payment of dividends, the issuance of other indebtedness or the issuance or repurchase of securities by us. The 2017 Indenture contains customary events of default with respect to the 2024 Notes, including that upon certain events of default, 100 % of the principal and accrued and unpaid interest on the 2024 Notes will automatically become due and payable. </context>
us-gaap:DebtInstrumentRedemptionPricePercentageOfPrincipalAmountRedeemed
Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021.
text
4.7
sharesItemType
text: <entity> 4.7 </entity> <entity type> sharesItemType </entity type> <context> Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021. </context>
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021.
text
4.6
sharesItemType
text: <entity> 4.6 </entity> <entity type> sharesItemType </entity type> <context> Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021. </context>
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021.
text
4.1
sharesItemType
text: <entity> 4.1 </entity> <entity type> sharesItemType </entity type> <context> Shares which have been excluded from diluted per share amounts because their effect would have been anti-dilutive were 4.7 million for 2023, 4.6 million for 2022 and 4.1 million for 2021. </context>
us-gaap:AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
In May 2022, our stockholders approved an amendment of the 2020 Equity Incentive Plan (as so amended, the Amended 2020 Plan). The Amended 2020 Plan provides for the grant of stock options, stock appreciation rights, restricted stock awards, restricted stock unit awards, performance awards, and other awards. As of December 31, 2023, 10.5 million shares of common stock remain available for future grant under the Amended 2020 Plan.
text
10.5
sharesItemType
text: <entity> 10.5 </entity> <entity type> sharesItemType </entity type> <context> In May 2022, our stockholders approved an amendment of the 2020 Equity Incentive Plan (as so amended, the Amended 2020 Plan). The Amended 2020 Plan provides for the grant of stock options, stock appreciation rights, restricted stock awards, restricted stock unit awards, performance awards, and other awards. As of December 31, 2023, 10.5 million shares of common stock remain available for future grant under the Amended 2020 Plan. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
In May 2011, we adopted the 2011 Equity Incentive Plan (the 2011 Plan). The 2011 Plan was a stockholder-approved plan pursuant to which outstanding awards have been made, but from which no further awards can or will be made.
text
no
sharesItemType
text: <entity> no </entity> <entity type> sharesItemType </entity type> <context> In May 2011, we adopted the 2011 Equity Incentive Plan (the 2011 Plan). The 2011 Plan was a stockholder-approved plan pursuant to which outstanding awards have been made, but from which no further awards can or will be made. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
In May 2021, our stockholders approved an amendment and restatement of the 2018 Employee Stock Purchase Plan (as so amended and restated, the Amended 2018 ESPP). As of December 31, 2023, 0.5 million shares of common stock remain available for future issuance under the Amended 2018 ESPP.
text
0.5
sharesItemType
text: <entity> 0.5 </entity> <entity type> sharesItemType </entity type> <context> In May 2021, our stockholders approved an amendment and restatement of the 2018 Employee Stock Purchase Plan (as so amended and restated, the Amended 2018 ESPP). As of December 31, 2023, 0.5 million shares of common stock remain available for future issuance under the Amended 2018 ESPP. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021.
text
45.19
perShareItemType
text: <entity> 45.19 </entity> <entity type> perShareItemType </entity type> <context> Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021.
text
32.05
perShareItemType
text: <entity> 32.05 </entity> <entity type> perShareItemType </entity type> <context> Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021.
text
45.02
perShareItemType
text: <entity> 45.02 </entity> <entity type> perShareItemType </entity type> <context> Typically, stock options have a 10-year term and vest over a three to four-year period. The exercise price of stock options granted is equal to the closing price of our common stock on the date of grant. We estimate the fair value of stock options using the Black-Scholes option-pricing model on the date of grant. The Black-Scholes option-pricing model incorporates various and highly sensitive assumptions including expected volatility, term and interest rates. The weighted-average grant-date fair values of stock options granted were $ 45.19 for 2023, $ 32.05 for 2022 and $ 45.02 for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
39.9
monetaryItemType
text: <entity> 39.9 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
39.7
monetaryItemType
text: <entity> 39.7 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
58.0
monetaryItemType
text: <entity> 58.0 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
55.5
monetaryItemType
text: <entity> 55.5 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ProceedsFromStockOptionsExercised
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
37.0
monetaryItemType
text: <entity> 37.0 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ProceedsFromStockOptionsExercised
The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021.
text
20.7
monetaryItemType
text: <entity> 20.7 </entity> <entity type> monetaryItemType </entity type> <context> The total intrinsic value of stock options exercised was $ 39.9 million for 2023, $ 39.7 million for 2022 and $ 58.0 million for 2021. Cash received from stock option exercises was $ 55.5 million for 2023, $ 37.0 million for 2022 and $ 20.7 million for 2021. </context>
us-gaap:ProceedsFromStockOptionsExercised
RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021.
text
101.0
monetaryItemType
text: <entity> 101.0 </entity> <entity type> monetaryItemType </entity type> <context> RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021. </context>
us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021.
text
72.4
monetaryItemType
text: <entity> 72.4 </entity> <entity type> monetaryItemType </entity type> <context> RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021. </context>
us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021.
text
64.3
monetaryItemType
text: <entity> 64.3 </entity> <entity type> monetaryItemType </entity type> <context> RSUs typically vest over a four-year period and may be subject to a deferred delivery arrangement at the election of eligible employees. The fair value of RSUs is based on the closing sale price of our common stock on the date of issuance. The total fair value of RSUs that vested was $ 101.0 million for 2023, $ 72.4 million for 2022 and $ 64.3 million for 2021. </context>
us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
PRSUs vest based on the achievement of certain predefined Company-specific performance criteria. Any unvested PRSUs will expire if it is determined the related performance criteria has not been met during the applicable three to four-year performance period. The fair value of PRSUs is estimated based on the closing sale price of our common stock on the date of grant. The fair value of PRSUs that vested during 2023 was $ 34.4 million. No PRSUs vested during 2022 or 2021.
text
34.4
monetaryItemType
text: <entity> 34.4 </entity> <entity type> monetaryItemType </entity type> <context> PRSUs vest based on the achievement of certain predefined Company-specific performance criteria. Any unvested PRSUs will expire if it is determined the related performance criteria has not been met during the applicable three to four-year performance period. The fair value of PRSUs is estimated based on the closing sale price of our common stock on the date of grant. The fair value of PRSUs that vested during 2023 was $ 34.4 million. No PRSUs vested during 2022 or 2021. </context>
us-gaap:ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodTotalFairValue
Under the Amended 2018 ESPP, eligible employees may purchase shares of our common stock at a discount semi-annually based on a percentage of their annual compensation. The discounted purchase price is equal to the lower of 85 % of (i) the market value per share of the common stock on the first day of the offering period or (ii) the market value per share of common stock on the purchase date.
text
85
percentItemType
text: <entity> 85 </entity> <entity type> percentItemType </entity type> <context> Under the Amended 2018 ESPP, eligible employees may purchase shares of our common stock at a discount semi-annually based on a percentage of their annual compensation. The discounted purchase price is equal to the lower of 85 % of (i) the market value per share of the common stock on the first day of the offering period or (ii) the market value per share of common stock on the purchase date. </context>
us-gaap:SharebasedCompensationArrangementBySharebasedPaymentAwardPurchasePriceOfCommonStockPercent
As of December 31, 2023, our deferred tax assets were primarily the result of net operating loss carry forwards, capitalized research costs, acquired intangible assets and tax credit carryforwards. As of December 31, 2023 and 2022, we recorded a valuation allowance of $ 88.9 million and $ 67.0 million, respectively, against our gross deferred tax asset balance.
text
88.9
monetaryItemType
text: <entity> 88.9 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, our deferred tax assets were primarily the result of net operating loss carry forwards, capitalized research costs, acquired intangible assets and tax credit carryforwards. As of December 31, 2023 and 2022, we recorded a valuation allowance of $ 88.9 million and $ 67.0 million, respectively, against our gross deferred tax asset balance. </context>
us-gaap:DeferredTaxAssetsValuationAllowance
As of December 31, 2023, our deferred tax assets were primarily the result of net operating loss carry forwards, capitalized research costs, acquired intangible assets and tax credit carryforwards. As of December 31, 2023 and 2022, we recorded a valuation allowance of $ 88.9 million and $ 67.0 million, respectively, against our gross deferred tax asset balance.
text
67.0
monetaryItemType
text: <entity> 67.0 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, our deferred tax assets were primarily the result of net operating loss carry forwards, capitalized research costs, acquired intangible assets and tax credit carryforwards. As of December 31, 2023 and 2022, we recorded a valuation allowance of $ 88.9 million and $ 67.0 million, respectively, against our gross deferred tax asset balance. </context>
us-gaap:DeferredTaxAssetsValuationAllowance
As of each reporting date, management considers new evidence, both positive and negative, that could affect its assessment of the future realizability of our deferred tax assets. As of December 31, 2023, management determined there was sufficient positive evidence to conclude that it is more likely than not deferred tax assets of $ 362.6 million are realizable. The recorded valuation allowance of $ 88.9 million consisted primarily of state and foreign net operating loss carryforwards and state credit carryforwards for which management cannot conclude it is more likely than not to be realized.
text
362.6
monetaryItemType
text: <entity> 362.6 </entity> <entity type> monetaryItemType </entity type> <context> As of each reporting date, management considers new evidence, both positive and negative, that could affect its assessment of the future realizability of our deferred tax assets. As of December 31, 2023, management determined there was sufficient positive evidence to conclude that it is more likely than not deferred tax assets of $ 362.6 million are realizable. The recorded valuation allowance of $ 88.9 million consisted primarily of state and foreign net operating loss carryforwards and state credit carryforwards for which management cannot conclude it is more likely than not to be realized. </context>
us-gaap:DeferredTaxAssetsLiabilitiesNet
As of each reporting date, management considers new evidence, both positive and negative, that could affect its assessment of the future realizability of our deferred tax assets. As of December 31, 2023, management determined there was sufficient positive evidence to conclude that it is more likely than not deferred tax assets of $ 362.6 million are realizable. The recorded valuation allowance of $ 88.9 million consisted primarily of state and foreign net operating loss carryforwards and state credit carryforwards for which management cannot conclude it is more likely than not to be realized.
text
88.9
monetaryItemType
text: <entity> 88.9 </entity> <entity type> monetaryItemType </entity type> <context> As of each reporting date, management considers new evidence, both positive and negative, that could affect its assessment of the future realizability of our deferred tax assets. As of December 31, 2023, management determined there was sufficient positive evidence to conclude that it is more likely than not deferred tax assets of $ 362.6 million are realizable. The recorded valuation allowance of $ 88.9 million consisted primarily of state and foreign net operating loss carryforwards and state credit carryforwards for which management cannot conclude it is more likely than not to be realized. </context>
us-gaap:DeferredTaxAssetsValuationAllowance
As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely.
text
286.0
monetaryItemType
text: <entity> 286.0 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely. </context>
us-gaap:OperatingLossCarryforwards
As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely.
text
134.3
monetaryItemType
text: <entity> 134.3 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely. </context>
us-gaap:OperatingLossCarryforwards
As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely.
text
no
monetaryItemType
text: <entity> no </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, we had state and foreign income tax net operating loss carryforwards of $ 286.0 million and $ 134.3 million, respectively. We had no federal income tax operating loss carryforwards as of December 31, 2023. California net operating losses will begin to expire in 2029 unless previously utilized and the net operating losses related to other states will begin to expire in 2026. Swiss net operating losses will begin to expire in 2030 unless previously utilized. UK net operating losses will carry forward indefinitely. </context>
us-gaap:OperatingLossCarryforwards
As of December 31, 2023, we had state R&D tax credit carryforwards of $ 85.6 million. California R&D tax credits carry forward indefinitely, while R&D tax credits related to other states will begin to expire in 2033 unless previously utilized.
text
85.6
monetaryItemType
text: <entity> 85.6 </entity> <entity type> monetaryItemType </entity type> <context> As of December 31, 2023, we had state R&D tax credit carryforwards of $ 85.6 million. California R&D tax credits carry forward indefinitely, while R&D tax credits related to other states will begin to expire in 2033 unless previously utilized. </context>
us-gaap:DeferredTaxAssetsTaxCreditCarryforwardsResearch
We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021.
text
3.1
monetaryItemType
text: <entity> 3.1 </entity> <entity type> monetaryItemType </entity type> <context> We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021. </context>
us-gaap:IncomeTaxExaminationInterestAccrued
We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021.
text
1.2
monetaryItemType
text: <entity> 1.2 </entity> <entity type> monetaryItemType </entity type> <context> We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021. </context>
us-gaap:IncomeTaxExaminationInterestAccrued
We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021.
text
2.2
monetaryItemType
text: <entity> 2.2 </entity> <entity type> monetaryItemType </entity type> <context> We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021. </context>
us-gaap:IncomeTaxExaminationPenaltiesAccrued
We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021.
text
0.4
monetaryItemType
text: <entity> 0.4 </entity> <entity type> monetaryItemType </entity type> <context> We recognize interest and penalties related to income tax matters in income tax expense. We had accruals for interest related to income tax matters of $ 3.1 million and $ 1.2 million, respectively, as of December 31, 2023 and 2022. We had accruals for penalties relates to income tax matters of $ 2.2 million and $ 0.4 million, respectively, as of December 31, 2023 and 2022. Accruals for interest and penalties related to income tax matters were not material as of December 31, 2021. </context>
us-gaap:IncomeTaxExaminationPenaltiesAccrued