Split (1)

test · 52.6k rows

context stringlengths 21 24.6k	category stringclasses 2 values	entity stringlengths 1 12	entity_type stringclasses 5 values	query stringlengths 97 3.31k	answer stringlengths 12 168
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	678	monetaryItemType	table: <entity> 678 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInOtherOperatingAssets
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	925	monetaryItemType	table: <entity> 925 </entity> <entity type> monetaryItemType </entity type> <context> Other noncurrent assets \| ( 1,084 ) \| ( 678 ) \| 925 </context>	us-gaap:IncreaseDecreaseInOtherOperatingAssets
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3354	monetaryItemType	table: <entity> 3354 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInAccountsPayable
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	6017	monetaryItemType	table: <entity> 6017 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInAccountsPayable
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	5858	monetaryItemType	table: <entity> 5858 </entity> <entity type> monetaryItemType </entity type> <context> Accounts payable \| ( 3,354 ) \| ( 6,017 ) \| 5,858 </context>	us-gaap:IncreaseDecreaseInAccountsPayable
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3654	monetaryItemType	table: <entity> 3654 </entity> <entity type> monetaryItemType </entity type> <context> Accrued compensation and other related benefits \| 3,654 \| ( 2,637 ) \| 1,114 </context>	us-gaap:IncreaseDecreaseInEmployeeRelatedLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	2637	monetaryItemType	table: <entity> 2637 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInEmployeeRelatedLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	1114	monetaryItemType	table: <entity> 1114 </entity> <entity type> monetaryItemType </entity type> <context> Accrued compensation and other related benefits \| 3,654 \| ( 2,637 ) \| 1,114 </context>	us-gaap:IncreaseDecreaseInEmployeeRelatedLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	11209	monetaryItemType	table: <entity> 11209 </entity> <entity type> monetaryItemType </entity type> <context> Deferred revenue \| 11,209 \| 10,932 \| 3,350 </context>	us-gaap:IncreaseDecreaseInDeferredRevenue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	10932	monetaryItemType	table: <entity> 10932 </entity> <entity type> monetaryItemType </entity type> <context> Deferred revenue \| 11,209 \| 10,932 \| 3,350 </context>	us-gaap:IncreaseDecreaseInDeferredRevenue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3350	monetaryItemType	table: <entity> 3350 </entity> <entity type> monetaryItemType </entity type> <context> Deferred revenue \| 11,209 \| 10,932 \| 3,350 </context>	us-gaap:IncreaseDecreaseInDeferredRevenue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	12484	monetaryItemType	table: <entity> 12484 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	8671	monetaryItemType	table: <entity> 8671 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	6423	monetaryItemType	table: <entity> 6423 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	776	monetaryItemType	table: <entity> 776 </entity> <entity type> monetaryItemType </entity type> <context> Other noncurrent liabilities \| 776 \| 1,284 \| ( 2,942 ) </context>	us-gaap:IncreaseDecreaseInOtherNoncurrentLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	1284	monetaryItemType	table: <entity> 1284 </entity> <entity type> monetaryItemType </entity type> <context> Other noncurrent liabilities \| 776 \| 1,284 \| ( 2,942 ) </context>	us-gaap:IncreaseDecreaseInOtherNoncurrentLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	2942	monetaryItemType	table: <entity> 2942 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:IncreaseDecreaseInOtherNoncurrentLiabilities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	6664	monetaryItemType	table: <entity> 6664 </entity> <entity type> monetaryItemType </entity type> <context> Net cash provided by (used in) operating activities \| 6,664 \| ( 15,197 ) \| ( 33,606 ) </context>	us-gaap:NetCashProvidedByUsedInOperatingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	15197	monetaryItemType	table: <entity> 15197 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:NetCashProvidedByUsedInOperatingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	33606	monetaryItemType	table: <entity> 33606 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:NetCashProvidedByUsedInOperatingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3856	monetaryItemType	table: <entity> 3856 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from sales of marketable securities \| 3,856 \| 100,191 \| 49,117 </context>	us-gaap:ProceedsFromSaleOfHeldToMaturitySecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	100191	monetaryItemType	table: <entity> 100191 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from sales of marketable securities \| 3,856 \| 100,191 \| 49,117 </context>	us-gaap:ProceedsFromSaleOfHeldToMaturitySecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	49117	monetaryItemType	table: <entity> 49117 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from sales of marketable securities \| 3,856 \| 100,191 \| 49,117 </context>	us-gaap:ProceedsFromSaleOfHeldToMaturitySecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	25782	monetaryItemType	table: <entity> 25782 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from maturities of marketable securities \| 25,782 \| 82,825 \| 18,528 </context>	us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	82825	monetaryItemType	table: <entity> 82825 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from maturities of marketable securities \| 25,782 \| 82,825 \| 18,528 </context>	us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	18528	monetaryItemType	table: <entity> 18528 </entity> <entity type> monetaryItemType </entity type> <context> Proceeds from maturities of marketable securities \| 25,782 \| 82,825 \| 18,528 </context>	us-gaap:ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	12393	monetaryItemType	table: <entity> 12393 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	48601	monetaryItemType	table: <entity> 48601 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	131661	monetaryItemType	table: <entity> 131661 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquirePropertyPlantAndEquipment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	1000	monetaryItemType	table: <entity> 1000 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquireIntangibleAssets
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	923	monetaryItemType	table: <entity> 923 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquireIntangibleAssets
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:PaymentsToAcquireIntangibleAssets
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	4000	monetaryItemType	table: <entity> 4000 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquireBusinessesNetOfCashAcquired
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	48876	monetaryItemType	table: <entity> 48876 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	282871	monetaryItemType	table: <entity> 282871 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsToAcquireAvailableForSaleSecuritiesDebt
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	32631	monetaryItemType	table: <entity> 32631 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:NetCashProvidedByUsedInInvestingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	133492	monetaryItemType	table: <entity> 133492 </entity> <entity type> monetaryItemType </entity type> <context> Net cash (used in) provided by investing activities \| ( 32,631 ) \| 133,492 \| ( 350,887 ) </context>	us-gaap:NetCashProvidedByUsedInInvestingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	350887	monetaryItemType	table: <entity> 350887 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:NetCashProvidedByUsedInInvestingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:PaymentsOfFinancingCosts
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	5814	monetaryItemType	table: <entity> 5814 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsOfFinancingCosts
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	5409	monetaryItemType	table: <entity> 5409 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsOfFinancingCosts
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	10914	monetaryItemType	table: <entity> 10914 </entity> <entity type> monetaryItemType </entity type> <context> Issuance of common stock from exercise of stock options and employee stock purchase plan purchases \| 10,914 \| 19,483 \| 21,226 </context>	us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	19483	monetaryItemType	table: <entity> 19483 </entity> <entity type> monetaryItemType </entity type> <context> Issuance of common stock from exercise of stock options and employee stock purchase plan purchases \| 10,914 \| 19,483 \| 21,226 </context>	us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	21226	monetaryItemType	table: <entity> 21226 </entity> <entity type> monetaryItemType </entity type> <context> Issuance of common stock from exercise of stock options and employee stock purchase plan purchases \| 10,914 \| 19,483 \| 21,226 </context>	us-gaap:ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	10914	monetaryItemType	table: <entity> 10914 </entity> <entity type> monetaryItemType </entity type> <context> Issuance of common stock from exercise of stock options and employee stock purchase plan purchases \| 10,914 \| 19,483 \| 21,226 </context>	us-gaap:NetCashProvidedByUsedInFinancingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	13669	monetaryItemType	table: <entity> 13669 </entity> <entity type> monetaryItemType </entity type> <context> Net cash provided by financing activities \| 10,914 \| 13,669 \| 15,817 </context>	us-gaap:NetCashProvidedByUsedInFinancingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	15817	monetaryItemType	table: <entity> 15817 </entity> <entity type> monetaryItemType </entity type> <context> Net cash provided by financing activities \| 10,914 \| 13,669 \| 15,817 </context>	us-gaap:NetCashProvidedByUsedInFinancingActivities
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	164	monetaryItemType	table: <entity> 164 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	33	monetaryItemType	table: <entity> 33 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	44	monetaryItemType	table: <entity> 44 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	15217	monetaryItemType	table: <entity> 15217 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	131931	monetaryItemType	table: <entity> 131931 </entity> <entity type> monetaryItemType </entity type> <context> Net (decrease) increase in cash, cash equivalents, and restricted cash \| ( 15,217 ) \| 131,931 \| ( 368,720 ) </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	368720	monetaryItemType	table: <entity> 368720 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	359284	monetaryItemType	table: <entity> 359284 </entity> <entity type> monetaryItemType </entity type> <context> Cash, cash equivalents, and restricted cash at beginning of year \| 359,284 \| 227,353 \| 596,073 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	227353	monetaryItemType	table: <entity> 227353 </entity> <entity type> monetaryItemType </entity type> <context> Cash, cash equivalents, and restricted cash at beginning of year \| 359,284 \| 227,353 \| 596,073 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	596073	monetaryItemType	table: <entity> 596073 </entity> <entity type> monetaryItemType </entity type> <context> Cash, cash equivalents, and restricted cash at beginning of year \| 359,284 \| 227,353 \| 596,073 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	344067	monetaryItemType	table: <entity> 344067 </entity> <entity type> monetaryItemType </entity type> <context> Cash, cash equivalents, and restricted cash at end of year \| $ \| 344,067 \| $ \| 359,284 \| $ \| 227,353 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:InterestPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	436	monetaryItemType	table: <entity> 436 </entity> <entity type> monetaryItemType </entity type> <context> Cash paid for interest \| $ \| — \| $ \| 436 \| $ \| 841 </context>	us-gaap:InterestPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	841	monetaryItemType	table: <entity> 841 </entity> <entity type> monetaryItemType </entity type> <context> Cash paid for interest \| $ \| — \| $ \| 436 \| $ \| 841 </context>	us-gaap:InterestPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	5641	monetaryItemType	table: <entity> 5641 </entity> <entity type> monetaryItemType </entity type> <context> Cash paid for taxes \| $ \| 5,641 \| $ \| 4,927 \| $ \| 3,925 </context>	us-gaap:IncomeTaxesPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	4927	monetaryItemType	table: <entity> 4927 </entity> <entity type> monetaryItemType </entity type> <context> Cash paid for taxes \| $ \| 5,641 \| $ \| 4,927 \| $ \| 3,925 </context>	us-gaap:IncomeTaxesPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3925	monetaryItemType	table: <entity> 3925 </entity> <entity type> monetaryItemType </entity type> <context> Cash paid for taxes \| $ \| 5,641 \| $ \| 4,927 \| $ \| 3,925 </context>	us-gaap:IncomeTaxesPaidNet
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	1351	monetaryItemType	table: <entity> 1351 </entity> <entity type> monetaryItemType </entity type> <context> Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities \| $ \| 1,351 \| $ \| 3,324 \| $ \| 26,750 </context>	us-gaap:CapitalExpendituresIncurredButNotYetPaid
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	3324	monetaryItemType	table: <entity> 3324 </entity> <entity type> monetaryItemType </entity type> <context> Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities \| $ \| 1,351 \| $ \| 3,324 \| $ \| 26,750 </context>	us-gaap:CapitalExpendituresIncurredButNotYetPaid
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	26750	monetaryItemType	table: <entity> 26750 </entity> <entity type> monetaryItemType </entity type> <context> Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities \| $ \| 1,351 \| $ \| 3,324 \| $ \| 26,750 </context>	us-gaap:CapitalExpendituresIncurredButNotYetPaid
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Lease and asset impairment charges \| 3,054 \| 9,845 \| — </context>	us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	6518	monetaryItemType	table: <entity> 6518 </entity> <entity type> monetaryItemType </entity type> <context> Right-of-use assets obtained in exchange for new operating lease liabilities \| $ \| — \| $ \| 6,518 \| $ \| 16,562 </context>	us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Net loss</td><td>$</td><td>( 182,627 )</td><td></td><td></td><td>$</td><td>( 255,099 )</td><td></td><td></td><td>$</td><td>( 166,000 )</td><td></td></tr><tr><td>Adjustments to reconcile net loss to net cash provided by (used in) operating activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Stock-based compensation expense</td><td>140,749</td><td></td><td></td><td>166,950</td><td></td><td></td><td>136,848</td><td></td></tr><tr><td>Depreciation and amortization</td><td>35,879</td><td></td><td></td><td>35,512</td><td></td><td></td><td>25,368</td><td></td></tr><tr><td>Lease and asset impairment charges</td><td>3,054</td><td></td><td></td><td>9,845</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Amortization of right-of-use assets</td><td>7,829</td><td></td><td></td><td>8,107</td><td></td><td></td><td>7,638</td><td></td></tr><tr><td>Realized loss on marketable securities</td><td>3</td><td></td><td></td><td>1,718</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Other</td><td>523</td><td></td><td></td><td>427</td><td></td><td></td><td>1,957</td><td></td></tr><tr><td>Changes in operating assets and liabilities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accounts receivable</td><td>26,951</td><td></td><td></td><td>( 10,613 )</td><td></td><td></td><td>( 18,948 )</td><td></td></tr><tr><td>Inventory</td><td>( 9,777 )</td><td></td><td></td><td>7,871</td><td></td><td></td><td>( 21,192 )</td><td></td></tr><tr><td>Prepaid expenses and other current assets</td><td>( 1,901 )</td><td></td><td></td><td>( 2,429 )</td><td></td><td></td><td>( 4,495 )</td><td></td></tr><tr><td>Other noncurrent assets</td><td>( 1,084 )</td><td></td><td></td><td>( 678 )</td><td></td><td></td><td>925</td><td></td></tr><tr><td>Accounts payable</td><td>( 3,354 )</td><td></td><td></td><td>( 6,017 )</td><td></td><td></td><td>5,858</td><td></td></tr><tr><td>Accrued compensation and other related benefits</td><td>3,654</td><td></td><td></td><td>( 2,637 )</td><td></td><td></td><td>1,114</td><td></td></tr><tr><td>Deferred revenue</td><td>11,209</td><td></td><td></td><td>10,932</td><td></td><td></td><td>3,350</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Accrued expenses and other current liabilities</td><td>( 12,736 )</td><td></td><td></td><td>28,301</td><td></td><td></td><td>3,336</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Operating lease liability</td><td>( 12,484 )</td><td></td><td></td><td>( 8,671 )</td><td></td><td></td><td>( 6,423 )</td><td></td></tr><tr><td>Other noncurrent liabilities</td><td>776</td><td></td><td></td><td>1,284</td><td></td><td></td><td>( 2,942 )</td><td></td></tr><tr><td>Net cash provided by (used in) operating activities</td><td>6,664</td><td></td><td></td><td>( 15,197 )</td><td></td><td></td><td>( 33,606 )</td><td></td></tr><tr><td>Investing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Proceeds from sales of marketable securities</td><td>3,856</td><td></td><td></td><td>100,191</td><td></td><td></td><td>49,117</td><td></td></tr><tr><td>Proceeds from maturities of marketable securities</td><td>25,782</td><td></td><td></td><td>82,825</td><td></td><td></td><td>18,528</td><td></td></tr><tr><td>Purchases of property and equipment</td><td>( 12,393 )</td><td></td><td></td><td>( 48,601 )</td><td></td><td></td><td>( 131,661 )</td><td></td></tr><tr><td>Purchase of intangible assets</td><td>( 1,000 )</td><td></td><td></td><td>( 923 )</td><td></td><td></td><td>—</td><td></td></tr><tr><td>Acquisition of business, net of cash acquired</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>( 4,000 )</td><td></td></tr><tr><td>Purchase of marketable securities</td><td>( 48,876 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 282,871 )</td><td></td></tr><tr><td>Net cash (used in) provided by investing activities</td><td>( 32,631 )</td><td></td><td></td><td>133,492</td><td></td><td></td><td>( 350,887 )</td><td></td></tr><tr><td>Financing activities:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Payments on technology license financing arrangement</td><td>—</td><td></td><td></td><td>( 5,814 )</td><td></td><td></td><td>( 5,409 )</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Issuance of common stock from exercise of stock options and employee stock purchase plan purchases</td><td>10,914</td><td></td><td></td><td>19,483</td><td></td><td></td><td>21,226</td><td></td></tr><tr><td>Net cash provided by financing activities</td><td>10,914</td><td></td><td></td><td>13,669</td><td></td><td></td><td>15,817</td><td></td></tr><tr><td>Effect of exchange rate changes on cash, cash equivalents, and restricted cash</td><td>( 164 )</td><td></td><td></td><td>( 33 )</td><td></td><td></td><td>( 44 )</td><td></td></tr><tr><td>Net (decrease) increase in cash, cash equivalents, and restricted cash</td><td>( 15,217 )</td><td></td><td></td><td>131,931</td><td></td><td></td><td>( 368,720 )</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at beginning of year</td><td>359,284</td><td></td><td></td><td>227,353</td><td></td><td></td><td>596,073</td><td></td></tr><tr><td>Cash, cash equivalents, and restricted cash at end of year</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr><tr><td>Supplemental disclosures of cash flow information:</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Cash paid for interest</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>436</td><td></td><td></td><td>$</td><td>841</td><td></td></tr><tr><td>Cash paid for taxes</td><td>$</td><td>5,641</td><td></td><td></td><td>$</td><td>4,927</td><td></td><td></td><td>$</td><td>3,925</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Noncash investing and financing activities</td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Purchases of property and equipment included in accounts payable, accrued expenses and other current liabilities</td><td>$</td><td>1,351</td><td></td><td></td><td>$</td><td>3,324</td><td></td><td></td><td>$</td><td>26,750</td><td></td></tr><tr><td>Right-of-use assets obtained in exchange for new operating lease liabilities</td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>6,518</td><td></td><td></td><td>$</td><td>16,562</td><td></td></tr><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr></table>	table	16562	monetaryItemType	table: <entity> 16562 </entity> <entity type> monetaryItemType </entity type> <context> Right-of-use assets obtained in exchange for new operating lease liabilities \| $ \| — \| $ \| 6,518 \| $ \| 16,562 </context>	us-gaap:RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	344067	monetaryItemType	table: <entity> 344067 </entity> <entity type> monetaryItemType </entity type> <context> Cash and cash equivalents \| $ \| 344,067 \| $ \| 359,284 \| $ \| 219,746 </context>	us-gaap:CashAndCashEquivalentsAtCarryingValue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	359284	monetaryItemType	table: <entity> 359284 </entity> <entity type> monetaryItemType </entity type> <context> Cash and cash equivalents \| $ \| 344,067 \| $ \| 359,284 \| $ \| 219,746 </context>	us-gaap:CashAndCashEquivalentsAtCarryingValue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	219746	monetaryItemType	table: <entity> 219746 </entity> <entity type> monetaryItemType </entity type> <context> Cash and cash equivalents \| $ \| 344,067 \| $ \| 359,284 \| $ \| 219,746 </context>	us-gaap:CashAndCashEquivalentsAtCarryingValue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Restricted cash \| — \| — \| 7,607 </context>	us-gaap:RestrictedCash
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	7607	monetaryItemType	table: <entity> 7607 </entity> <entity type> monetaryItemType </entity type> <context> Restricted cash \| — \| — \| 7,607 </context>	us-gaap:RestrictedCash
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	344067	monetaryItemType	table: <entity> 344067 </entity> <entity type> monetaryItemType </entity type> <context> Cash and cash equivalents \| $ \| 344,067 \| $ \| 359,284 \| $ \| 219,746 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	359284	monetaryItemType	table: <entity> 359284 </entity> <entity type> monetaryItemType </entity type> <context> Cash and cash equivalents \| $ \| 344,067 \| $ \| 359,284 \| $ \| 219,746 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>Year Ended December 31,</td></tr><tr><td></td><td>2024</td><td></td><td>2023</td><td></td><td>2022</td></tr><tr><td>Cash and cash equivalents</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>219,746</td><td></td></tr><tr><td>Restricted cash</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>7,607</td><td></td></tr><tr><td>Total cash, cash equivalents and restricted cash</td><td>$</td><td>344,067</td><td></td><td></td><td>$</td><td>359,284</td><td></td><td></td><td>$</td><td>227,353</td><td></td></tr></table>	table	227353	monetaryItemType	table: <entity> 227353 </entity> <entity type> monetaryItemType </entity type> <context> Total cash, cash equivalents and restricted cash \| $ \| 344,067 \| $ \| 359,284 \| $ \| 227,353 </context>	us-gaap:CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Balance at January 1, 2022 \| $ \| — \| $ \| — \| $ \| — </context>	us-gaap:RestructuringReserve
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	4216	monetaryItemType	table: <entity> 4216 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 4,216 \| — \| 4,216 </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Balance at January 1, 2022 \| $ \| — \| $ \| — \| $ \| — </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	3385	monetaryItemType	table: <entity> 3385 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsForRestructuring
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Balance at January 1, 2022 \| $ \| — \| $ \| — \| $ \| — </context>	us-gaap:PaymentsForRestructuring
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	616	monetaryItemType	table: <entity> 616 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:RestructuringReserveTranslationAndOtherAdjustment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	215	monetaryItemType	table: <entity> 215 </entity> <entity type> monetaryItemType </entity type> <context> Balance at December 31, 2022 \| 215 \| — \| 215 </context>	us-gaap:RestructuringReserve
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	310	monetaryItemType	table: <entity> 310 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 310 \| 2,171 \| 2,481 </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	2171	monetaryItemType	table: <entity> 2171 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 310 \| 2,171 \| 2,481 </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	2481	monetaryItemType	table: <entity> 2481 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 310 \| 2,171 \| 2,481 </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	215	monetaryItemType	table: <entity> 215 </entity> <entity type> monetaryItemType </entity type> <context> Balance at December 31, 2022 \| 215 \| — \| 215 </context>	us-gaap:PaymentsForRestructuring
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Balance at January 1, 2022 \| $ \| — \| $ \| — \| $ \| — </context>	us-gaap:RestructuringReserveTranslationAndOtherAdjustment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	2171	monetaryItemType	table: <entity> 2171 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 310 \| 2,171 \| 2,481 </context>	us-gaap:RestructuringReserveTranslationAndOtherAdjustment
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	310	monetaryItemType	table: <entity> 310 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring charge \| 310 \| 2,171 \| 2,481 </context>	us-gaap:RestructuringReserve
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	259	monetaryItemType	table: <entity> 259 </entity> <entity type> monetaryItemType </entity type> <context> Restructuring Charge Restructuring Charge \| 259 \| — \| 259 </context>	us-gaap:RestructuringCharges
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td></td><td>Termination Benefits Costs</td><td></td><td>Long-lived Assets Impairment Expenses</td><td></td><td>Total</td></tr><tr><td>Balance at January 1, 2022</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>4,216</td><td></td><td></td><td>—</td><td></td><td></td><td>4,216</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 3,385 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 3,385 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>( 616 )</td><td></td><td></td><td></td><td></td><td>( 616 )</td><td></td></tr><tr><td>Balance at December 31, 2022</td><td></td><td>215</td><td></td><td></td><td>—</td><td></td><td></td><td>215</td><td></td></tr><tr><td>Restructuring charge</td><td></td><td>310</td><td></td><td></td><td>2,171</td><td></td><td></td><td>2,481</td><td></td></tr><tr><td>Cash payments made</td><td></td><td>( 215 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 215 )</td><td></td></tr><tr><td>Non-cash charge</td><td></td><td>—</td><td></td><td></td><td>( 2,171 )</td><td></td><td></td><td>( 2,171 )</td><td></td></tr><tr><td>Balance at December 31, 2023</td><td></td><td>310</td><td></td><td></td><td>—</td><td></td><td></td><td>310</td><td></td></tr><tr><td>Restructuring Charge Restructuring Charge</td><td></td><td>259</td><td></td><td></td><td>—</td><td></td><td></td><td>259</td><td></td></tr><tr><td>Cash payments made Cash payments made</td><td></td><td>( 569 )</td><td></td><td></td><td>—</td><td></td><td></td><td>( 569 )</td><td></td></tr><tr><td>Balance at December 31, 2024 Balance at December 31, 2024</td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td></tr></table>	table	569	monetaryItemType	table: <entity> 569 </entity> <entity type> monetaryItemType </entity type> <context> None </context>	us-gaap:PaymentsForRestructuring
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Assets Acquired and Liabilities Assumed</td><td></td></tr><tr><td>In-process research and development</td><td>$</td><td>60,980</td><td></td></tr><tr><td>Intangible assets - acquired workforce</td><td>200</td><td></td></tr><tr><td>Property and equipment</td><td>671</td><td></td></tr><tr><td>Operating lease liabilities</td><td>( 1,496 )</td><td></td></tr><tr><td>Other assets and liabilities, net</td><td>758</td><td></td></tr><tr><td>Total net assets acquired</td><td>$</td><td>61,113</td><td></td></tr></table>	table	60980	monetaryItemType	table: <entity> 60980 </entity> <entity type> monetaryItemType </entity type> <context> In-process research and development \| $ \| 60,980 </context>	us-gaap:IndefinitelivedIntangibleAssetsAcquired
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Assets Acquired and Liabilities Assumed</td><td></td></tr><tr><td>In-process research and development</td><td>$</td><td>60,980</td><td></td></tr><tr><td>Intangible assets - acquired workforce</td><td>200</td><td></td></tr><tr><td>Property and equipment</td><td>671</td><td></td></tr><tr><td>Operating lease liabilities</td><td>( 1,496 )</td><td></td></tr><tr><td>Other assets and liabilities, net</td><td>758</td><td></td></tr><tr><td>Total net assets acquired</td><td>$</td><td>61,113</td><td></td></tr></table>	table	200	monetaryItemType	table: <entity> 200 </entity> <entity type> monetaryItemType </entity type> <context> Intangible assets - acquired workforce \| 200 </context>	us-gaap:FinitelivedIntangibleAssetsAcquired1
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>December 31, 2024</td><td></td><td>December 31, 2023</td><td></td><td></td></tr><tr><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Fair Value Measurement</td></tr><tr><td>Cash equivalents:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Money market funds</td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>Level 1</td></tr><tr><td>Marketable securities:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Corporate debt securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>10,022</td><td></td><td></td><td>—</td><td></td><td></td><td>( 51 )</td><td></td><td></td><td>9,971</td><td></td><td></td><td>Level 2</td></tr><tr><td>Government debt securities</td><td>49,317</td><td></td><td></td><td>18</td><td></td><td></td><td>—</td><td></td><td></td><td>49,335</td><td></td><td></td><td>18,152</td><td></td><td></td><td>—</td><td></td><td></td><td>( 125 )</td><td></td><td></td><td>18,027</td><td></td><td></td><td>Level 2</td></tr><tr><td>Asset-backed securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>1,425</td><td></td><td></td><td>—</td><td></td><td></td><td>( 12 )</td><td></td><td></td><td>1,413</td><td></td><td></td><td>Level 2</td></tr><tr><td>Total available-for-sale securities</td><td>$</td><td>371,329</td><td></td><td></td><td>$</td><td>18</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>371,347</td><td></td><td></td><td>$</td><td>378,138</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>( 188 )</td><td></td><td></td><td>$</td><td>377,950</td><td></td><td></td><td></td></tr></table>	table	322012	monetaryItemType	table: <entity> 322012 </entity> <entity type> monetaryItemType </entity type> <context> Money market funds \| $ \| 322,012 \| $ \| — \| $ \| — \| $ \| 322,012 \| $ \| 348,539 \| $ \| — \| $ \| — \| $ \| 348,539 \| Level 1 </context>	us-gaap:MoneyMarketFundsAtCarryingValue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>December 31, 2024</td><td></td><td>December 31, 2023</td><td></td><td></td></tr><tr><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Fair Value Measurement</td></tr><tr><td>Cash equivalents:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Money market funds</td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>Level 1</td></tr><tr><td>Marketable securities:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Corporate debt securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>10,022</td><td></td><td></td><td>—</td><td></td><td></td><td>( 51 )</td><td></td><td></td><td>9,971</td><td></td><td></td><td>Level 2</td></tr><tr><td>Government debt securities</td><td>49,317</td><td></td><td></td><td>18</td><td></td><td></td><td>—</td><td></td><td></td><td>49,335</td><td></td><td></td><td>18,152</td><td></td><td></td><td>—</td><td></td><td></td><td>( 125 )</td><td></td><td></td><td>18,027</td><td></td><td></td><td>Level 2</td></tr><tr><td>Asset-backed securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>1,425</td><td></td><td></td><td>—</td><td></td><td></td><td>( 12 )</td><td></td><td></td><td>1,413</td><td></td><td></td><td>Level 2</td></tr><tr><td>Total available-for-sale securities</td><td>$</td><td>371,329</td><td></td><td></td><td>$</td><td>18</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>371,347</td><td></td><td></td><td>$</td><td>378,138</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>( 188 )</td><td></td><td></td><td>$</td><td>377,950</td><td></td><td></td><td></td></tr></table>	table	348539	monetaryItemType	table: <entity> 348539 </entity> <entity type> monetaryItemType </entity type> <context> Money market funds \| $ \| 322,012 \| $ \| — \| $ \| — \| $ \| 322,012 \| $ \| 348,539 \| $ \| — \| $ \| — \| $ \| 348,539 \| Level 1 </context>	us-gaap:MoneyMarketFundsAtCarryingValue
<table><tr><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td></td><td>December 31, 2024</td><td></td><td>December 31, 2023</td><td></td><td></td></tr><tr><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Amortized Cost</td><td></td><td>Gross Unrealized Gains</td><td></td><td>Gross Unrealized Losses</td><td></td><td>Fair Value</td><td></td><td>Fair Value Measurement</td></tr><tr><td>Cash equivalents:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Money market funds</td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>322,012</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>348,539</td><td></td><td></td><td>Level 1</td></tr><tr><td>Marketable securities:</td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td><td></td></tr><tr><td>Corporate debt securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>10,022</td><td></td><td></td><td>—</td><td></td><td></td><td>( 51 )</td><td></td><td></td><td>9,971</td><td></td><td></td><td>Level 2</td></tr><tr><td>Government debt securities</td><td>49,317</td><td></td><td></td><td>18</td><td></td><td></td><td>—</td><td></td><td></td><td>49,335</td><td></td><td></td><td>18,152</td><td></td><td></td><td>—</td><td></td><td></td><td>( 125 )</td><td></td><td></td><td>18,027</td><td></td><td></td><td>Level 2</td></tr><tr><td>Asset-backed securities</td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>—</td><td></td><td></td><td>1,425</td><td></td><td></td><td>—</td><td></td><td></td><td>( 12 )</td><td></td><td></td><td>1,413</td><td></td><td></td><td>Level 2</td></tr><tr><td>Total available-for-sale securities</td><td>$</td><td>371,329</td><td></td><td></td><td>$</td><td>18</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>371,347</td><td></td><td></td><td>$</td><td>378,138</td><td></td><td></td><td>$</td><td>—</td><td></td><td></td><td>$</td><td>( 188 )</td><td></td><td></td><td>$</td><td>377,950</td><td></td><td></td><td></td></tr></table>	table	—	monetaryItemType	table: <entity> — </entity> <entity type> monetaryItemType </entity type> <context> Money market funds \| $ \| 322,012 \| $ \| — \| $ \| — \| $ \| 322,012 \| $ \| 348,539 \| $ \| — \| $ \| — \| $ \| 348,539 \| Level 1 </context>	us-gaap:AvailableForSaleDebtSecuritiesAmortizedCostBasis

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