meta_pmid int64 | meta_language string | meta_mesh_ids list | meta_mesh_terms list | meta_pubdate_year string | meta_pubdate_month string | text string |
|---|---|---|---|---|---|---|
9,633,918 | eng | [
"D000255",
"Q000378",
"D000818",
"D002118",
"Q000378",
"D006332",
"Q000378",
"D003600",
"Q000378",
"D003971",
"Q000502",
"D004195",
"D004558",
"D004594",
"D005456",
"D006973",
"Q000378",
"D066298",
"D007211",
"D008297",
"D008928",
"Q000378",
"D009206",
"Q000378",
"D00... | [
"Adenosine Triphosphate",
"Animals",
"Calcium",
"Cardiomegaly",
"Cytosol",
"Diastole",
"Disease Models, Animal",
"Electric Stimulation",
"Electrophysiology",
"Fluorescent Dyes",
"Hypertension",
"In Vitro Techniques",
"Indoles",
"Male",
"Mitochondria",
"Myocardium",
"Myofibrils",
"N... | 1998 | Jun | Regulation of mitochondrial [NADH] by cytosolic [Ca2+] and work in trabeculae from hypertrophic and normal rat hearts.
Pressure overload hypertrophy has previously been shown to reduce contractility but paradoxically to increase O2 consumption rates at a given force. Because O2 consumption rates are related to mitochon... |
9,633,920 | eng | [
"D000200",
"Q000502",
"D001145",
"Q000209",
"Q000503",
"D002118",
"Q000378",
"D015220",
"Q000502",
"D002478",
"D003198",
"D006329",
"Q000166",
"Q000503",
"D006333",
"Q000150",
"Q000503",
"D006352",
"Q000737",
"Q000166",
"Q000378",
"D006801",
"D008955",
"D018485",
"Q00... | [
"Action Potentials",
"Arrhythmias, Cardiac",
"Calcium",
"Calcium Channels",
"Cells, Cultured",
"Computer Simulation",
"Heart Conduction System",
"Heart Failure",
"Heart Ventricles",
"Humans",
"Models, Cardiovascular",
"Muscle Fibers, Skeletal",
"Myocardium",
"Patch-Clamp Techniques",
"Po... | 1998 | Jun | Simulation study of cellular electric properties in heart failure.
Patients with severe heart failure are at high risk of sudden cardiac death. In the majority of these patients, sudden cardiac death is thought to be due to ventricular tachyarrhythmias. Alterations of the electric properties of single myocytes in heart... |
9,633,919 | eng | [
"D000818",
"D003243",
"D003326",
"Q000502",
"D003327",
"Q000473",
"Q000503",
"D004699",
"Q000473",
"D006439",
"Q000502",
"D009200",
"Q000502",
"D017682",
"Q000473",
"Q000503",
"D009206",
"Q000473",
"D009336",
"D010496",
"Q000473",
"D013552"
] | [
"Animals",
"Consciousness",
"Coronary Circulation",
"Coronary Disease",
"Endocardium",
"Hemodynamics",
"Myocardial Contraction",
"Myocardial Stunning",
"Myocardium",
"Necrosis",
"Pericardium",
"Swine"
] | 1998 | Jun | Ineffective perfusion-contraction matching in conscious, chronically instrumented pigs with an extended period of coronary stenosis.
Several models purported to represent hibernating myocardium involve a coronary stenosis (CS) to reduce blood flow (BF) and function without eliciting necrosis in anesthetized pigs. The g... |
9,633,921 | eng | [
"D000818",
"D001921",
"Q000378",
"D003176",
"Q000235",
"D003186",
"Q000235",
"D017931",
"D005786",
"D008099",
"Q000378",
"D008297",
"D009203",
"Q000378",
"D017202",
"Q000378",
"D015428",
"Q000378",
"D019696",
"Q000235",
"D012333",
"Q000378",
"D011817",
"D013154",
"Q00... | [
"Animals",
"Brain",
"Complement C3",
"Complement C9",
"DNA Primers",
"Gene Expression Regulation",
"Liver",
"Male",
"Myocardial Infarction",
"Myocardial Ischemia",
"Myocardial Reperfusion Injury",
"Peptidylprolyl Isomerase",
"RNA, Messenger",
"Rabbits",
"Spleen"
] | 1998 | Jun | Complement gene expression by rabbit heart: upregulation by ischemia and reperfusion.
Activation of the complement system has been implicated in the pathogenesis of myocardial ischemia/reperfusion injury. It has always been assumed that liver is the primary source of complement components. In the present study, we used... |
9,633,923 | eng | [
"D000818",
"D006801",
"D007554",
"D050356",
"D008432",
"D008954"
] | [
"Animals",
"Humans",
"Isotopes",
"Lipid Metabolism",
"Mathematical Computing",
"Models, Biological"
] | 1998 | Jun | Development of compartmental models in stable-isotope experiments: application to lipid metabolism.
Kinetic experiments are of great importance in lipid research because they further the understanding of lipid metabolism in vivo and help to explain the physiopathology of lipid disorders in humans. At present, due to sp... |
9,633,924 | eng | [
"D000328",
"D015703",
"Q000096",
"D001792",
"Q000187",
"Q000378",
"D002118",
"Q000378",
"D002462",
"Q000378",
"D003029",
"Q000494",
"D000242",
"Q000378",
"D017868",
"Q000378",
"D004075",
"Q000378",
"D005340",
"Q000378",
"D006801",
"D015544",
"Q000378",
"D007424",
"D00... | [
"Adult",
"Antigens, CD",
"Blood Platelets",
"Calcium",
"Cell Membrane",
"Coagulants",
"Cyclic AMP",
"Cyclic AMP-Dependent Protein Kinases",
"Diglycerides",
"Fibrinogen",
"Humans",
"Inositol 1,4,5-Trisphosphate",
"Intracellular Fluid",
"Lipoproteins, HDL",
"Middle Aged",
"Phosphatidic A... | 1998 | Jun | HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate.
We demonstrate that physiological concentrations of HDL3 inhibit the thrombin-induced platelet fibr... |
9,633,926 | eng | [
"D000208",
"D000328",
"D000368",
"D000369",
"D001161",
"Q000378",
"D003327",
"Q000378",
"D005260",
"D006801",
"D015227",
"D008077",
"Q000378",
"D008297",
"D008875",
"D009203",
"Q000378",
"D019158",
"Q000378"
] | [
"Acute Disease",
"Adult",
"Aged",
"Aged, 80 and over",
"Arteriosclerosis",
"Coronary Disease",
"Female",
"Humans",
"Lipid Peroxidation",
"Lipoproteins, LDL",
"Male",
"Middle Aged",
"Myocardial Infarction",
"N-Acetylneuraminic Acid"
] | 1998 | Jun | Sialic acid content of LDL in coronary artery disease: no evidence of desialylation in subjects with coronary stenosis and increased levels in subjects with extensive atherosclerosis and acute myocardial infarction: relation between desialylation and in vitro peroxidation.
We recently showed that sialic acid content of... |
9,633,925 | eng | [
"D001809",
"D003327",
"Q000097",
"Q000503",
"D006801",
"D016015",
"D008297",
"D008875",
"D009203",
"Q000097"
] | [
"Blood Viscosity",
"Coronary Disease",
"Humans",
"Logistic Models",
"Male",
"Middle Aged",
"Myocardial Infarction"
] | 1998 | Jun | Relationship between plasma viscosity and the severity of coronary heart disease.
Several studies have indicated that plasma viscosity contributes to cardiovascular risk in men. So far, a significant relationship between plasma viscosity and the severity of coronary heart disease has not been found. Thus, the present s... |
9,633,927 | eng | [
"D000328",
"D000818",
"D001158",
"Q000378",
"Q000473",
"Q000648",
"D002448",
"D004195",
"D004730",
"Q000378",
"Q000648",
"D006801",
"D018799",
"Q000096",
"Q000235",
"D008077",
"Q000378",
"D008297",
"D009000",
"Q000378",
"D016328",
"Q000378",
"D010084",
"D051381",
"D01... | [
"Adult",
"Animals",
"Arteries",
"Cell Adhesion",
"Disease Models, Animal",
"Endothelium, Vascular",
"Humans",
"Intercellular Adhesion Molecule-1",
"Lipoproteins, LDL",
"Male",
"Monocytes",
"NF-kappa B",
"Oxidation-Reduction",
"Rats",
"Rats, Sprague-Dawley"
] | 1998 | Jun | An animal model to study local oxidation of LDL and its biological effects in the arterial wall.
Oxidized LDL (oxLDL) is present in atherosclerotic lesions and is believed to play a key role in atherogenesis. Mainly on the basis of cell culture studies, oxLDL has been shown to produce many biological effects that influ... |
9,633,929 | eng | [
"D000818",
"D001011",
"D001161",
"Q000097",
"Q000139",
"Q000517",
"D002784",
"Q000097",
"D002791",
"Q000008",
"D004357",
"D004958",
"Q000494",
"D005260",
"D008074",
"Q000097",
"D009640",
"Q000031",
"Q000494",
"D000077563",
"D010052",
"D011817"
] | [
"Animals",
"Aorta",
"Arteriosclerosis",
"Cholesterol",
"Cholesterol, Dietary",
"Drug Synergism",
"Estradiol",
"Female",
"Lipoproteins",
"Norethindrone",
"Norethindrone Acetate",
"Ovariectomy",
"Rabbits"
] | 1998 | Jun | Norethindrone acetate enhances the antiatherogenic effect of 17beta-estradiol: a secondary prevention study of aortic atherosclerosis in ovariectomized cholesterol-fed rabbits.
The influence of progestogens in combination with 17beta-estradiol (E2) on cardiovascular disease remains controversial. This study investigate... |
9,633,930 | eng | [
"D000818",
"D000925",
"Q000627",
"D003328",
"Q000097",
"Q000503",
"Q000517",
"D003331",
"D004195",
"D004285",
"D004305",
"D017984",
"Q000627",
"D015951",
"Q000378",
"D005260",
"D006439",
"D006493",
"Q000627",
"D008297",
"D010314",
"D011516",
"Q000378",
"D011517",
"D01... | [
"Animals",
"Anticoagulants",
"Coronary Thrombosis",
"Coronary Vessels",
"Disease Models, Animal",
"Dogs",
"Dose-Response Relationship, Drug",
"Enoxaparin",
"Factor Xa",
"Female",
"Hemodynamics",
"Heparin",
"Male",
"Partial Thromboplastin Time",
"Prothrombin",
"Prothrombin Time",
"Rec... | 1998 | Jun | Inhibition of repetitive thrombus formation in the stenosed canine coronary artery by enoxaparin, but not by unfractionated heparin.
Experiments were designed to compare the antithrombotic efficacy of enoxaparin and unfractionated heparin (UH) in a model of platelet-dependent cyclic flow reductions (CFRs) in the stenos... |
9,633,931 | eng | [
"D000818",
"D018821",
"Q000378",
"D002339",
"Q000473",
"D016893",
"Q000209",
"Q000473",
"D004487",
"Q000209",
"D005434",
"D016179",
"Q000008",
"D007958",
"D008297",
"D009504",
"Q000502",
"D011817",
"D012867",
"Q000503"
] | [
"Animals",
"CD18 Antigens",
"Carotid Arteries",
"Carotid Stenosis",
"Edema",
"Flow Cytometry",
"Granulocyte Colony-Stimulating Factor",
"Leukocyte Count",
"Male",
"Neutrophils",
"Rabbits",
"Skin"
] | 1998 | Jun | Role of polymorphonuclear leukocytes in collar-induced intimal thickening in the rabbit carotid artery.
In this study, the involvement of polymorphonuclear leukocytes (PMNs) in the development of intimal thickening was investigated. A fibromuscular intima was induced by placing a silicone collar around the rabbit carot... |
9,633,928 | eng | [
"D002478",
"D018932",
"Q000235",
"D016207",
"Q000378",
"D004730",
"Q000378",
"D006801",
"D016209",
"Q000235",
"D007473",
"Q000378",
"D010812",
"D011493",
"Q000502",
"D011505",
"Q000502",
"D012333",
"Q000378",
"D010738",
"Q000502",
"D015854"
] | [
"Cells, Cultured",
"Chemokine CCL2",
"Cytokines",
"Endothelium, Vascular",
"Humans",
"Interleukin-8",
"Ion Channels",
"Physical Stimulation",
"Protein Kinase C",
"Protein-Tyrosine Kinases",
"RNA, Messenger",
"Type C Phospholipases",
"Up-Regulation"
] | 1998 | Jun | Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in human endothelial cells.
In vivo, vascular walls are exposed to mechanical stretch, which may promote atherogenesis. This study was designed to investigate the effect of mechanical... |
9,633,932 | eng | [
"D000818",
"D001011",
"Q000378",
"D001696",
"D002135",
"Q000096",
"D002148",
"Q000096",
"D003285",
"Q000096",
"D004730",
"Q000378",
"D064448",
"D008297",
"D008840",
"Q000096",
"D009131",
"Q000378",
"D009218",
"Q000096",
"D009924",
"D011312",
"D011817",
"D000096985"
] | [
"Animals",
"Aorta",
"Biomechanical Phenomena",
"Calcium-Binding Proteins",
"Calmodulin-Binding Proteins",
"Contractile Proteins",
"Endothelium, Vascular",
"Filamins",
"Male",
"Microfilament Proteins",
"Muscle, Smooth, Vascular",
"Myosins",
"Organ Culture Techniques",
"Pressure",
"Rabbits... | 1998 | Jun | Intraluminal pressure is essential for the maintenance of smooth muscle caldesmon and filamin content in aortic organ culture.
Different forms of mechanical stimulation are among the physiological factors constantly acting on the vessel wall. We previously demonstrated that subjecting vascular smooth muscle cells (VSMC... |
9,633,933 | eng | [
"D001794",
"D015992",
"D002318",
"Q000453",
"Q000209",
"Q000378",
"D005951",
"D006801",
"D007328",
"Q000097",
"D020738",
"D008297",
"D008875",
"D015999",
"D011506",
"Q000378",
"D012307",
"D013577"
] | [
"Blood Pressure",
"Body Mass Index",
"Cardiovascular Diseases",
"Glucose Tolerance Test",
"Humans",
"Insulin",
"Leptin",
"Male",
"Middle Aged",
"Multivariate Analysis",
"Proteins",
"Risk Factors",
"Syndrome"
] | 1998 | Jun | Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk.
In humans, production of the adipocyte-derived peptide leptin has been linked to adiposity, insulin, and insulin sensitivity. We therefore considered that alterations in plasma leptin concentrations could constitute an additional component o... |
9,633,934 | eng | [
"D002478",
"D018932",
"Q000235",
"D003546",
"Q000378",
"D015853",
"Q000494",
"D004730",
"Q000378",
"D005786",
"D006801",
"D007375",
"Q000502",
"D007976",
"Q000494",
"D009097",
"Q000378",
"D016328",
"Q000378",
"D046988",
"D015842",
"Q000494",
"D014108",
"Q000494"
] | [
"Cells, Cultured",
"Chemokine CCL2",
"Cysteine Endopeptidases",
"Cysteine Proteinase Inhibitors",
"Endothelium, Vascular",
"Gene Expression Regulation",
"Humans",
"Interleukin-1",
"Leupeptins",
"Multienzyme Complexes",
"NF-kappa B",
"Proteasome Endopeptidase Complex",
"Serine Proteinase Inhi... | 1998 | Jun | IL-1beta-induced monocyte chemoattractant protein-1 gene expression in endothelial cells is blocked by proteasome inhibitors.
Human monocyte chemoattractant protein-1 (MCP-1) is expressed by a variety of cell types in response to various stimuli. MCP-1 expressed by the endothelium plays an important role in cell migrat... |
9,633,935 | eng | [
"D001120",
"D001794",
"D015992",
"D008078",
"Q000097",
"D015331",
"D003924",
"D004562",
"D005260",
"D005787",
"D005838",
"D006801",
"D007564",
"D008297",
"D008875",
"D009765",
"Q000097",
"Q000235",
"D017354",
"D011943",
"Q000235",
"D022702",
"D014280",
"Q000097",
"D01... | [
"Arginine",
"Blood Pressure",
"Body Mass Index",
"Cholesterol, LDL",
"Cohort Studies",
"Diabetes Mellitus, Type 2",
"Electrocardiography",
"Female",
"Gene Frequency",
"Genotype",
"Humans",
"Japan",
"Male",
"Middle Aged",
"Obesity",
"Point Mutation",
"Receptors, Adrenergic, beta",
"... | 1998 | Jun | Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.
To characterize the clinical features associated with the Trp64Arg mutation of the beta3-adrenergic receptor (beta3-AR), the effects of this mutation, in particu... |
9,633,936 | eng | [
"D000818",
"D001013",
"Q000378",
"D001786",
"Q000032",
"D001794",
"D002448",
"D003921",
"Q000378",
"Q000503",
"D004730",
"Q000503",
"D006973",
"Q000378",
"Q000503",
"D007328",
"Q000097",
"D008297",
"D051379",
"D009000",
"Q000378",
"D051381",
"D011918",
"D011921",
"D01... | [
"Animals",
"Aorta, Thoracic",
"Blood Glucose",
"Blood Pressure",
"Cell Adhesion",
"Diabetes Mellitus, Experimental",
"Endothelium, Vascular",
"Hypertension",
"Insulin",
"Male",
"Mice",
"Monocytes",
"Rats",
"Rats, Inbred SHR",
"Rats, Inbred WKY",
"Triglycerides"
] | 1998 | Jun | Interaction of diabetes and hypertension on determinants of endothelial adhesiveness.
Epidemiological studies have established that diabetes mellitus and hypertension are independent risk factors for atherosclerosis. One of the earliest abnormalities seen in atherogenesis is enhanced monocyte adherence to the endotheli... |
9,633,937 | eng | [
"D000818",
"D001555",
"Q000737",
"Q000494",
"D002118",
"Q000097",
"D002341",
"Q000097",
"Q000473",
"Q000517",
"D002951",
"D004195",
"D004285",
"D005260",
"D006493",
"D008297",
"D015394",
"D010975",
"Q000494",
"D019038",
"D010980",
"D011956",
"Q000037"
] | [
"Animals",
"Benzene Derivatives",
"Calcium",
"Carotid Artery Thrombosis",
"Citrates",
"Disease Models, Animal",
"Dogs",
"Female",
"Heparin",
"Male",
"Molecular Structure",
"Platelet Aggregation Inhibitors",
"Platelet Glycoprotein GPIb-IX Complex",
"Platelet Membrane Glycoproteins",
"Rece... | 1998 | Jun | In vivo efficacy of SM-20302, a GP IIb/IIIa receptor antagonist, correlates with ex vivo platelet inhibition in heparinized blood but not in citrated blood.
We tested the hypothesis that the in vivo antithrombotic efficacy of SM-20302, a GP IIb/IIIa receptor antagonist, correlates with the ex vivo platelet inhibition i... |
9,633,938 | eng | [
"D000328",
"D001792",
"Q000187",
"Q000378",
"D002118",
"Q000378",
"D000242",
"Q000378",
"D006152",
"Q000378",
"D004958",
"Q000378",
"Q000494",
"D005260",
"D006801",
"D008297",
"D009569",
"Q000096",
"D010974",
"Q000187",
"D010975",
"Q000378",
"Q000494"
] | [
"Adult",
"Blood Platelets",
"Calcium",
"Cyclic AMP",
"Cyclic GMP",
"Estradiol",
"Female",
"Humans",
"Male",
"Nitric Oxide",
"Platelet Aggregation",
"Platelet Aggregation Inhibitors"
] | 1998 | Jun | Effect of 17beta-estradiol on inhibition of platelet aggregation in vitro is mediated by an increase in NO synthesis.
The low prevalence of coronary heart disease in premenopausal women and its increase after menopause are well established. Although estrogen is thought to play a role in protecting the vasculature, the ... |
9,633,939 | eng | [
"D000906",
"Q000378",
"D053299",
"D053283",
"D001055",
"Q000378",
"D002914",
"Q000378",
"D005347",
"Q000378",
"D006493",
"Q000378",
"Q000494",
"D006801",
"D007781",
"Q000378",
"Q000494",
"D008071",
"Q000378",
"D008079",
"Q000378",
"D008264",
"Q000378",
"D009000",
"Q00... | [
"Antibodies",
"Apolipoprotein B-100",
"Apolipoprotein B-48",
"Apolipoproteins B",
"Chylomicrons",
"Fibroblasts",
"Heparin",
"Humans",
"Lactoferrin",
"Lipoprotein Lipase",
"Lipoproteins, VLDL",
"Macrophages",
"Monocytes",
"Receptors, LDL",
"Receptors, Lipoprotein",
"Triglycerides",
"T... | 1998 | Jun | Apolipoprotein B-48 or its apolipoprotein B-100 equivalent mediates the binding of triglyceride-rich lipoproteins to their unique human monocyte-macrophage receptor.
Studies in animals and humans have demonstrated uptake of plasma chylomicrons (triglyceride-rich lipoprotein [TGRLP] of Sf>400) by accessible macrophages ... |
9,633,940 | eng | [
"D000818",
"D001011",
"Q000473",
"D001161",
"Q000209",
"Q000473",
"D002784",
"Q000378",
"D002791",
"Q000378",
"D008078",
"Q000097",
"D015243",
"Q000378",
"D008297",
"D010084",
"D011817"
] | [
"Animals",
"Aorta",
"Arteriosclerosis",
"Cholesterol",
"Cholesterol, Dietary",
"Cholesterol, LDL",
"Cholesterol, VLDL",
"Male",
"Oxidation-Reduction",
"Rabbits"
] | 1998 | Jun | Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits.
Oxidized lipoproteins may play a role in atherosclerosis. Recently, we have demonstrated that the levels of oxidized fatty acids in the circulation correlate directly with the quantity of oxidized fatty ac... |
9,633,941 | eng | [
"D000818",
"D001053",
"Q000235",
"D053241",
"D002478",
"D016207",
"Q000494",
"D005786",
"Q000187",
"D006801",
"D015850",
"Q000494",
"D017270",
"Q000235",
"D008099",
"Q000166",
"D008252",
"D008297",
"D012333",
"D016212",
"Q000494",
"D014409",
"Q000494"
] | [
"Animals",
"Apolipoproteins",
"Apoprotein(a)",
"Cells, Cultured",
"Cytokines",
"Gene Expression Regulation",
"Humans",
"Interleukin-6",
"Lipoprotein(a)",
"Liver",
"Macaca fascicularis",
"Male",
"RNA, Messenger",
"Transforming Growth Factor beta",
"Tumor Necrosis Factor-alpha"
] | 1998 | Jun | Dominant negative effect of TGF-beta1 and TNF-alpha on basal and IL-6-induced lipoprotein(a) and apolipoprotein(a) mRNA expression in primary monkey hepatocyte cultures.
Lipoprotein(a) [Lp(a)] consists of apolipoprotein(a) [apo(a)] disulfide linked to apolipoprotein B-100 of LDL. Elevated plasma Lp(a) is an independent... |
9,633,942 | eng | [
"D000818",
"D000906",
"Q000378",
"Q000494",
"D003994",
"Q000494",
"D002460",
"D002478",
"D002788",
"Q000378",
"D005260",
"D005487",
"Q000166",
"D015870",
"D006868",
"D008264",
"Q000378",
"D017737",
"Q000378",
"D051379",
"D008810",
"D051381",
"D002787",
"Q000235",
"Q00... | [
"Animals",
"Antibodies",
"Bucladesine",
"Cell Line",
"Cells, Cultured",
"Cholesterol Esters",
"Female",
"Foam Cells",
"Gene Expression",
"Hydrolysis",
"Macrophages",
"Macrophages, Peritoneal",
"Mice",
"Mice, Inbred C57BL",
"Rats",
"Sterol Esterase",
"Transfection"
] | 1998 | Jun | Hormone-sensitive lipase overexpression increases cholesteryl ester hydrolysis in macrophage foam cells.
Atherosclerosis is a complex physiopathologic process initiated by the formation of cholesterol-rich lesions in the arterial wall. Macrophages play a crucial role in this process because they accumulate large amount... |
9,633,943 | eng | [
"D016632",
"Q000096",
"Q000235",
"D016633",
"Q000096",
"Q000235",
"D002352",
"Q000378",
"D004958",
"Q000494",
"D006801",
"D008075",
"D011257",
"D012333",
"D019998",
"D014158",
"Q000187",
"D014407"
] | [
"Apolipoprotein A-I",
"Apolipoprotein A-II",
"Carrier Proteins",
"Estradiol",
"Humans",
"Lipoproteins, HDL",
"Pregnancy Proteins",
"RNA, Messenger",
"Racemases and Epimerases",
"Transcription, Genetic",
"Tumor Cells, Cultured"
] | 1998 | Jun | Estradiol stimulates apolipoprotein A-I- but not A-II-containing particle synthesis and secretion by stimulating mRNA transcription rate in Hep G2 cells.
Estrogen therapy increases plasma HDL levels, which may reduce cardiovascular risk in postmenopausal women. The mechanism of action of estrogen in influencing various... |
9,633,944 | eng | [
"D000293",
"D000924",
"Q000494",
"D001055",
"Q000097",
"D002170",
"D002648",
"D008078",
"Q000097",
"D004311",
"D005260",
"D006579",
"D006801",
"D019161",
"Q000494",
"D006938",
"Q000097",
"Q000188",
"Q000235",
"D008074",
"Q000097",
"D008297",
"D017354",
"D011973",
"Q00... | [
"Adolescent",
"Anticholesteremic Agents",
"Apolipoproteins B",
"Canada",
"Child",
"Cholesterol, LDL",
"Double-Blind Method",
"Female",
"Heterozygote",
"Humans",
"Hydroxymethylglutaryl-CoA Reductase Inhibitors",
"Hyperlipoproteinemia Type II",
"Lipoproteins",
"Male",
"Point Mutation",
"... | 1998 | Jun | Association of specific LDL receptor gene mutations with differential plasma lipoprotein response to simvastatin in young French Canadians with heterozygous familial hypercholesterolemia.
In familial hypercholesterolemia (FH), the efficacy of the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase s... |
9,633,945 | eng | [
"D000071479",
"D000818",
"D053299",
"D001055",
"Q000235",
"Q000378",
"D015197",
"D003564",
"Q000096",
"Q000235",
"D006801",
"D008077",
"Q000378",
"D008107",
"Q000209",
"D008113",
"Q000209",
"D051379",
"D008810",
"D008813",
"D008822",
"D017393",
"D051381",
"D019076"
] | [
"APOBEC-1 Deaminase",
"Animals",
"Apolipoprotein B-100",
"Apolipoproteins B",
"Carcinogenicity Tests",
"Cytidine Deaminase",
"Humans",
"Lipoproteins, LDL",
"Liver Diseases",
"Liver Neoplasms",
"Mice",
"Mice, Inbred C57BL",
"Mice, Inbred ICR",
"Mice, Transgenic",
"RNA Editing",
"Rats",
... | 1998 | Jun | Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors.
Hepatic expression of apolipoprotein (apo) B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) has been proposed as a gene therapy approach for lowering plasma low density lipoprot... |
9,633,946 | eng | [
"D002516",
"D008670",
"D008854",
"Q000379",
"D013048",
"Q000379",
"D013499"
] | [
"Ceramics",
"Metals",
"Microscopy, Electron",
"Specimen Handling",
"Surface Properties"
] | 1998 | May | Applications of the FIB lift-out technique for TEM specimen preparation.
A site-specific technique for cross-section transmission electron microscopy specimen preparation of difficult materials is presented. A focused ion beam was used to slice an electron transparent membrane from a specific area of interest within a ... |
9,633,947 | eng | [
"D000447",
"D005404",
"D019276",
"Q000648",
"D006801",
"D008239",
"D008854",
"D012430",
"D013194",
"D013210",
"Q000648",
"D013997"
] | [
"Aldehydes",
"Fixatives",
"Glycocalyx",
"Humans",
"Lysine",
"Microscopy, Electron",
"Ruthenium Red",
"Staining and Labeling",
"Staphylococcus",
"Time Factors"
] | 1998 | May | Superior preservation of the staphylococcal glycocalyx with aldehyde-ruthenium red and select lysine salts using extended fixation times.
The utility of lysine-based aldehyde-ruthenium red fixatives for the preservation and/or staining of the fibrous staphylococcal glycocalyx was improved by substitution of alternative... |
9,633,948 | eng | [
"D000161",
"D000818",
"D001306",
"Q000033",
"Q000502",
"D001933",
"Q000033",
"Q000502",
"D002415",
"D003847",
"Q000378",
"D005456"
] | [
"Acoustic Stimulation",
"Animals",
"Auditory Pathways",
"Brain Stem",
"Cats",
"Deoxyglucose",
"Fluorescent Dyes"
] | 1998 | May | Lack of topography in the ventral nucleus of the lateral lemniscus.
In contrast to the ease of finding tonotopicity in other nuclei, both anatomical and electrophysiological methods have failed to demonstrate a clear and simple tonotopic map within the ventral nucleus of the lateral lemniscus (VLL). The present study w... |
9,633,949 | eng | [
"D000135",
"Q000032",
"D000469",
"Q000032",
"D000818",
"D001853",
"Q000187",
"Q000502",
"Q000648",
"D001862",
"D016222",
"Q000494",
"D007150",
"D017403",
"D008297",
"D008854",
"D010006",
"Q000201",
"Q000648",
"D010010",
"Q000201",
"Q000648",
"D010012",
"D015676",
"Q00... | [
"Acid Phosphatase",
"Alkaline Phosphatase",
"Animals",
"Bone Marrow",
"Bone Resorption",
"Fibroblast Growth Factor 2",
"Immunohistochemistry",
"In Situ Hybridization",
"Male",
"Microscopy, Electron",
"Osteoblasts",
"Osteoclasts",
"Osteogenesis",
"Osteonectin",
"Osteopontin",
"Rats",
... | 1998 | May | Morphological examination of bone synthesis via direct administration of basic fibroblast growth factor into rat bone marrow.
Woven bone induced by direct injection of basic fibroblast growth factor (bFGF) into rat bone marrow was examined. On the first day after injection, fibrous tissues formed in the treated region ... |
9,633,950 | eng | [
"D015100",
"D000818",
"D002196",
"Q000648",
"D003051",
"Q000098",
"Q000648",
"D015834",
"Q000139",
"Q000473",
"D006168",
"D008027",
"D008855",
"D010777",
"D012395",
"D013194",
"Q000379",
"D013927"
] | [
"3,3'-Diaminobenzidine",
"Animals",
"Capillaries",
"Cochlea",
"Cochlear Diseases",
"Guinea Pigs",
"Light",
"Microscopy, Electron, Scanning",
"Photochemistry",
"Rose Bengal",
"Staining and Labeling",
"Thrombosis"
] | 1998 | May | Photochemically induced focal cochlear lesions in the guinea pig: I. DAB staining and SEM study.
A photochemical reaction was used to produce focal microcirculation disorders in the guinea pig cochlea. Temporal bones were removed at various intervals between 5 minutes and 1 month after infusion of rose bengal (RB) and ... |
9,633,951 | eng | [
"D000818",
"D002196",
"Q000648",
"D003051",
"Q000098",
"Q000648",
"D015834",
"Q000139",
"Q000473",
"D005260",
"D006168",
"D008027",
"D008854",
"D009925",
"Q000648",
"D010777",
"D012395",
"D013194",
"Q000379",
"D013316",
"Q000648",
"D013927",
"D013997"
] | [
"Animals",
"Capillaries",
"Cochlea",
"Cochlear Diseases",
"Female",
"Guinea Pigs",
"Light",
"Microscopy, Electron",
"Organ of Corti",
"Photochemistry",
"Rose Bengal",
"Staining and Labeling",
"Stria Vascularis",
"Thrombosis",
"Time Factors"
] | 1998 | May | Photochemically induced focal cochlear lesions in the guinea pig: II. A transmission electron microscope study.
Photochemically induced focal lesions in guinea pig cochleas were studied by light microscopy and transmission electron microscopy. The lesions were induced in the second cochlear turns of 35 adult guinea pig... |
9,633,952 | eng | [
"D000818",
"D001011",
"Q000000981",
"D005240",
"D008297",
"D012077",
"Q000000981",
"D012756",
"D018615",
"D018616",
"D018084"
] | [
"Animals",
"Aorta",
"Feasibility Studies",
"Male",
"Renal Artery",
"Sheep",
"Ultrasonography, Doppler, Color",
"Ultrasonography, Doppler, Duplex",
"Ultrasonography, Interventional"
] | 1998 | May | Biplane color flow duplex intravenous intravascular ultrasound for arterial visualization.
To describe a feasibility study in a sheep model using an intravascular ultrasound (IVUS) instrument in an intravenous position to produce color flow, B-mode images of arterial segments along with Doppler blood flow velocities. F... |
9,633,953 | eng | [
"D000328",
"D000368",
"D000369",
"D000783",
"Q000000981",
"D019917",
"D002445",
"Q000000981",
"D005260",
"D005263",
"Q000000981",
"D006801",
"D007083",
"Q000000981",
"D007432",
"D008297",
"D008875",
"D015607",
"D018084"
] | [
"Adult",
"Aged",
"Aged, 80 and over",
"Aneurysm",
"Blood Vessel Prosthesis Implantation",
"Celiac Artery",
"Female",
"Femoral Artery",
"Humans",
"Iliac Artery",
"Intraoperative Period",
"Male",
"Middle Aged",
"Stents",
"Ultrasonography, Interventional"
] | 1998 | May | Intravascular ultrasound in endovascular stent-grafts for peripheral aneurysm: a clinical study.
To evaluate the potential diagnostic information of intraprocedural intravascular ultrasound (IVUS) in patients undergoing endovascular stent-grafting for peripheral aneurysm. IVUS was used in 17 patients preprocedurally to... |
9,633,954 | eng | [
"D001014",
"Q000628",
"D002404",
"Q000295",
"D006801",
"D011312"
] | [
"Aortic Aneurysm",
"Catheterization",
"Humans",
"Pressure"
] | 1998 | May | Diameter of large balloons used in endoluminal graft deployment varies with inflation pressure.
To evaluate the characteristics of large-diameter balloon catheters used during endoluminal repair of aortic aneurysms. Thirty-three large balloon dilatation catheters in the diameter range of 15 to 30 mm were measured at co... |
9,633,955 | eng | [
"D000328",
"D017541",
"Q000209",
"Q000601",
"D001013",
"Q000293",
"D017545",
"Q000209",
"Q000601",
"D001807",
"D019917",
"Q000379",
"D006801",
"D008297",
"D015607",
"D014950",
"Q000150"
] | [
"Adult",
"Aneurysm, False",
"Aorta, Thoracic",
"Aortic Aneurysm, Thoracic",
"Blood Vessel Prosthesis",
"Blood Vessel Prosthesis Implantation",
"Humans",
"Male",
"Stents",
"Wounds, Penetrating"
] | 1998 | May | Treatment of traumatic false aneurysm of the thoracic aorta with endoluminal grafts.
Traumatic false aneurysms of the thoracic aorta presenting at a time remote from the original injury are a rare but complex problem. The treatment of a traumatic false aneurysm by endovascular techniques may offer many advantages over ... |
9,633,956 | eng | [
"D000818",
"D002404",
"D004285",
"D008433",
"D015588",
"D019047",
"D014159",
"D018084"
] | [
"Animals",
"Catheterization",
"Dogs",
"Mathematics",
"Observer Variation",
"Phantoms, Imaging",
"Transducers",
"Ultrasonography, Interventional"
] | 1998 | May | The effect of angulation on intravascular ultrasound imaging observed in vascular phantoms.
To quantify the error introduced by noncoaxial intravascular ultrasound (IVUS) imaging and to evaluate the use of a balloon-tipped catheter in compensating for intraluminal angulation and subsequent dimensional inaccuracy. The e... |
9,633,957 | eng | [
"D000328",
"D000792",
"D017544",
"Q000000981",
"Q000601",
"D001019",
"Q000000981",
"Q000601",
"D019917",
"D004630",
"D004638",
"D005260",
"D006801",
"D015607",
"D013997"
] | [
"Adult",
"Angiography",
"Aortic Aneurysm, Abdominal",
"Aortic Rupture",
"Blood Vessel Prosthesis Implantation",
"Emergencies",
"Emergency Treatment",
"Female",
"Humans",
"Stents",
"Time Factors"
] | 1998 | May | Emergent endoluminal repair of delayed abdominal aortic rupture after blunt trauma.
To report the emergency repair of a traumatic abdominal aortic rupture using endoluminal techniques. A 25-year-old female sustained multiple head, chest, and abdominal injuries in a motorcycle accident. Six days after emergency treatmen... |
9,633,958 | eng | [
"D000368",
"D017541",
"Q000209",
"Q000601",
"D001166",
"D019917",
"D006801",
"D008297",
"D011138",
"Q000627",
"D011183",
"D006435",
"D015607"
] | [
"Aged",
"Aneurysm, False",
"Arteriovenous Shunt, Surgical",
"Blood Vessel Prosthesis Implantation",
"Humans",
"Male",
"Polytetrafluoroethylene",
"Postoperative Complications",
"Renal Dialysis",
"Stents"
] | 1998 | May | Transluminal stent-graft repair for pseudoaneurysm of PTFE hemodialysis grafts.
To report the use of endovascular techniques to treat two cases of nonanastomotic pseudoaneurysm of a bridge graft fistula (BGF). Two men with fully functional polytetrafluoroethylene (PTFE) BGFs both presented with an enlarging mass adjace... |
9,633,959 | eng | [
"D000368",
"D000369",
"D000783",
"Q000150",
"D001166",
"D019917",
"D004621",
"D005268",
"D006801",
"D007083",
"D007084",
"D008297",
"D019060",
"D011312",
"D015607",
"D013924",
"Q000209",
"Q000601"
] | [
"Aged",
"Aged, 80 and over",
"Aneurysm",
"Arteriovenous Shunt, Surgical",
"Blood Vessel Prosthesis Implantation",
"Embolization, Therapeutic",
"Femoral Vein",
"Humans",
"Iliac Artery",
"Iliac Vein",
"Male",
"Minimally Invasive Surgical Procedures",
"Pressure",
"Stents",
"Thrombophlebitis... | 1998 | May | Iliofemoral venous thrombosis caused by compression of an internal iliac artery aneurysm: a minimally invasive treatment.
To report the success of a minimally invasive treatment for phlegmasia cerulea dolens without gangrene caused by compression from an internal iliac artery aneurysm. An 81-year-old male with a 1-mont... |
9,633,963 | eng | [
"D000402",
"Q000473",
"D000818",
"D002356",
"Q000473",
"D002675",
"D004195",
"D004933",
"Q000473",
"D006801",
"D007223",
"D007231",
"D051381",
"D014132",
"Q000473",
"D014133",
"Q000473",
"D014138",
"Q000473"
] | [
"Airway Obstruction",
"Animals",
"Cartilage",
"Child, Preschool",
"Disease Models, Animal",
"Esophageal Atresia",
"Humans",
"Infant",
"Infant, Newborn",
"Rats",
"Trachea",
"Tracheal Diseases",
"Tracheoesophageal Fistula"
] | 1998 | Jun | Understanding tracheomalacia.
Tracheomalacia is an abnormality of the trachea that probably is present to some degree in all infants and children with oesophageal atresia. It causes the trachea to collapse during breathing, leading to obstruction of the upper airway. Our knowledge of the structural abnormalities underl... |
9,633,964 | eng | [
"D000553",
"D001315",
"D002648",
"D002669",
"Q000639",
"D003153",
"Q000639",
"D003479",
"Q000639",
"D004504",
"Q000639",
"D005544",
"D006801",
"D010372",
"Q000193",
"D018794"
] | [
"Ambulatory Care",
"Australia",
"Child",
"Child Welfare",
"Community Health Services",
"Curriculum",
"Education, Medical, Undergraduate",
"Forecasting",
"Humans",
"Pediatrics",
"Problem-Based Learning"
] | 1998 | Jun | Medical student education in paediatrics and child health: where are we going?
In most undergraduate medical curricula, learning is becoming less content based and the emphasis is changing to problem based learning, continuing self directed learning, and the use of a wide range of learning resources. Particular needs i... |
9,633,965 | eng | [
"D001315",
"D019317",
"D006801",
"D007223",
"D017410",
"D012307",
"D013398",
"Q000209",
"Q000517"
] | [
"Australia",
"Evidence-Based Medicine",
"Humans",
"Infant",
"Practice Guidelines as Topic",
"Risk Factors",
"Sudden Infant Death"
] | 1998 | Jun | Reducing the risk of sudden infant death syndrome: a review of the scientific literature.
In March 1997 a multidisciplinary forum was convened by the National SIDS Council of Australia to review recent evidence concerning risk factors of sudden infant death syndrome (SIDS) and to revise and refine the current guideline... |
9,633,966 | eng | [
"D002648",
"D019988",
"Q000193",
"D004519",
"D006801",
"D008282",
"D010348"
] | [
"Child",
"Disabled Children",
"Education, Special",
"Humans",
"Mainstreaming, Education",
"Patient Care Team"
] | 1998 | Jun | Education for children with disabilities: the rationale for inclusion.
To discuss issues in the education of children with disabilities, particularly with respect to inclusion in mainstream classes. Review of the literature on education for children with disabilities, focusing on the inclusion versus segregation debate... |
9,633,967 | eng | [
"D000293",
"Q000502",
"D044466",
"D002118",
"Q000652",
"D003404",
"Q000652",
"D003431",
"D005260",
"D006723",
"D006801",
"D008297",
"D012016",
"D044465"
] | [
"Adolescent",
"Asian People",
"Calcium",
"Creatinine",
"Cross-Cultural Comparison",
"Female",
"Hong Kong",
"Humans",
"Male",
"Reference Values",
"White People"
] | 1998 | Jun | Urinary calcium excretion in Chinese adolescents.
To obtain normative reference values for urinary calcium excretion in Chinese adolescents. A random group of 425 healthy Chinese adolescents aged 12-19 years were recruited from secondary schools in Hong Kong. Each subject provided a sample of morning urine for the asse... |
9,633,969 | eng | [
"D000015",
"Q000453",
"Q000235",
"D000013",
"Q000453",
"Q000235",
"D003430",
"D005260",
"D006801",
"D015994",
"D007223",
"D007231",
"D008297",
"D011247",
"D012307",
"D014739",
"Q000453"
] | [
"Abnormalities, Multiple",
"Congenital Abnormalities",
"Cross-Sectional Studies",
"Female",
"Humans",
"Incidence",
"Infant",
"Infant, Newborn",
"Male",
"Pregnancy",
"Risk Factors",
"Victoria"
] | 1998 | Jun | Congenital malformations in Victoria, Australia, 1983-95: an overview of infant characteristics.
To provide an overview of the characteristics of Victorian infants born between 1983 and 1995 who are affected by one or more of 27 sentinel birth defects. Using data on congenital malformations supplied to the Victorian Pe... |
9,633,968 | eng | [
"D000818",
"D000941",
"Q000276",
"D002417",
"D002675",
"D003968",
"Q000276",
"D005260",
"D005500",
"D006801",
"D007223",
"D007768",
"Q000276",
"D007782",
"Q000276",
"D008297",
"D008892",
"Q000276",
"D016269",
"Q000276",
"D010047",
"Q000276",
"D012307",
"D012400",
"Q00... | [
"Animals",
"Antigens",
"Cattle",
"Child, Preschool",
"Diarrhea, Infantile",
"Female",
"Follow-Up Studies",
"Humans",
"Infant",
"Lactalbumin",
"Lactoglobulins",
"Male",
"Milk",
"Milk Hypersensitivity",
"Ovalbumin",
"Risk Factors",
"Rotavirus Infections",
"Serum Albumin, Bovine"
] | 1998 | Jun | Humoral immune and clinical responses to food antigens following acute diarrhoea in children.
To investigate the effect of acute watery diarrhoea in children upon humoral immune responses to food antigens and the subsequent development of food allergy. Serum antibodies to cows' milk, beta-lactoglobulin, alpha-lactalbum... |
9,633,971 | eng | [
"D001315",
"D019090",
"D002648",
"D002653",
"Q000175",
"Q000534",
"D002675",
"D003479",
"D002658",
"Q000175",
"Q000534",
"D005260",
"D006801",
"D008297",
"D010348",
"D010372",
"Q000193",
"D012017"
] | [
"Australia",
"Case Management",
"Child",
"Child Behavior Disorders",
"Child, Preschool",
"Curriculum",
"Developmental Disabilities",
"Female",
"Humans",
"Male",
"Patient Care Team",
"Pediatrics",
"Referral and Consultation"
] | 1998 | Jun | Developmental-behavioural problems in general paediatrics.
To determine the current role of private general paediatrics in the care of children with problems of development and behaviour. We surveyed all general paediatricians registered with the Australian College of Paediatrics to assess their current role in develop... |
9,633,972 | eng | [
"D018798",
"Q000453",
"Q000517",
"D003430",
"D005260",
"D006801",
"D015994",
"D007223",
"D019266",
"Q000008",
"D008297",
"D009751",
"D013021",
"Q000453"
] | [
"Anemia, Iron-Deficiency",
"Cross-Sectional Studies",
"Female",
"Humans",
"Incidence",
"Infant",
"Iron, Dietary",
"Male",
"Nutritional Requirements",
"South Australia"
] | 1998 | Jun | Iron status and dietary iron intake of 6-24-month-old children in Adelaide.
Chronic iron deficiency in children is associated with anaemia and impaired mental and psychomotor development. The aim of this study was to assess the iron status and dietary intake of 6-24-month-old Caucasian and Asian children living in metr... |
9,633,970 | eng | [
"D000773",
"D001034",
"D002585",
"D005260",
"D006301",
"D006801",
"D007231",
"D008297",
"D008485",
"D010348",
"D010372",
"D011247",
"D011446",
"D012151",
"D012307",
"D013648"
] | [
"Anesthesia, Obstetrical",
"Apgar Score",
"Cesarean Section",
"Female",
"Health Services Needs and Demand",
"Humans",
"Infant, Newborn",
"Male",
"Medical Audit",
"Patient Care Team",
"Pediatrics",
"Pregnancy",
"Prospective Studies",
"Resuscitation",
"Risk Factors",
"Tasmania"
] | 1998 | Jun | Is a paediatrician needed at all Caesarean sections?
The need for a skilled neonatal resuscitator in the form of a paediatrician or paediatric registrar to attend a vaginal delivery or Caesarean section (CS) is not clearly defined. This study was undertaken in order to ascertain the level of resuscitation a neonate mig... |
9,633,973 | eng | [
"D000293",
"D001315",
"D002648",
"D002675",
"D003431",
"D004739",
"D005260",
"D007722",
"D006801",
"D008297",
"D009381",
"Q000209",
"Q000517",
"D009520",
"D012878",
"Q000209",
"Q000517",
"D013471",
"Q000209",
"Q000517",
"D013472",
"Q000009",
"D013473",
"Q000008"
] | [
"Adolescent",
"Australia",
"Child",
"Child, Preschool",
"Cross-Cultural Comparison",
"England",
"Female",
"Health Knowledge, Attitudes, Practice",
"Humans",
"Male",
"Neoplasms, Radiation-Induced",
"New Zealand",
"Skin Neoplasms",
"Sunburn",
"Sunlight",
"Sunscreening Agents"
] | 1998 | Jun | Children's understanding of sun protection behaviours: a comparative analysis.
To investigate awareness of sun protection behaviours in a sample of primary school children in New Zealand. Information was collected from 824 primary school children in New Zealand using a drawing and writing technique. The data revealed a... |
9,633,974 | eng | [
"D000328",
"D001521",
"D019052",
"Q000175",
"Q000523",
"Q000628",
"D005260",
"D005500",
"D006801",
"D007223",
"D008297",
"D010348",
"D012892"
] | [
"Adult",
"Behavior Therapy",
"Depression, Postpartum",
"Female",
"Follow-Up Studies",
"Humans",
"Infant",
"Male",
"Patient Care Team",
"Sleep Deprivation"
] | 1998 | Jun | Sleep deprivation or postnatal depression in later infancy: separating the chicken from the egg.
To explore the association between maternal distress and depression in the first years of a newborn's life and the child's sleeping behaviour and problems associated with this behaviour. To asses the effectiveness of an out... |
9,633,976 | eng | [
"D000293",
"D001925",
"Q000175",
"Q000453",
"Q000628",
"D002648",
"D002653",
"Q000175",
"Q000453",
"Q000628",
"D015897",
"D002658",
"Q000175",
"Q000453",
"Q000628",
"D005260",
"D006801",
"D008297",
"D019965",
"Q000175",
"Q000453",
"Q000628",
"D009483",
"D010348",
"D01... | [
"Adolescent",
"Brain Damage, Chronic",
"Child",
"Child Behavior Disorders",
"Comorbidity",
"Developmental Disabilities",
"Female",
"Humans",
"Male",
"Neurocognitive Disorders",
"Neuropsychological Tests",
"Patient Care Team",
"Residential Treatment",
"Western Australia"
] | 1998 | Jun | Paediatric assessment in a residential child and adolescent psychiatry unit.
To document the health status, comorbidity and functional impairments experienced by a group of psychiatrically disturbed children and adolescents. A detailed study of consecutive admissions to a residential unit over a two-year period was und... |
9,633,975 | eng | [
"D000223",
"D000293",
"D000328",
"D002648",
"D002662",
"D019052",
"Q000175",
"Q000523",
"D005260",
"D006801",
"D007223",
"D008297",
"D009034",
"D010343",
"D011247",
"D011248",
"Q000175",
"Q000523",
"D012307",
"D012892",
"D012893",
"Q000175",
"Q000523"
] | [
"Adaptation, Psychological",
"Adolescent",
"Adult",
"Child",
"Child Health Services",
"Depression, Postpartum",
"Female",
"Humans",
"Infant",
"Male",
"Mother-Child Relations",
"Patient Admission",
"Pregnancy",
"Pregnancy Complications",
"Risk Factors",
"Sleep Deprivation",
"Sleep Wak... | 1998 | Jun | Childhood sleep problems: association with prenatal factors and maternal distress/depression.
To determine whether problems with childhood sleep behaviour are associated with either maternal sleep patterns and emotional status during the pregnancy period, or levels of maternal distress and depression during the postnat... |
9,633,977 | eng | [
"D000328",
"D000361",
"Q000175",
"Q000235",
"Q000276",
"D001402",
"Q000276",
"D002648",
"D002675",
"D005091",
"D005260",
"D006580",
"D006801",
"D007223",
"D008297",
"D016133",
"D011944",
"Q000235",
"D016511",
"Q000175",
"Q000235",
"Q000276",
"D012729",
"Q000235",
"D01... | [
"Adult",
"Agammaglobulinemia",
"B-Lymphocytes",
"Child",
"Child, Preschool",
"Exons",
"Female",
"Genetic Carrier Screening",
"Humans",
"Infant",
"Male",
"Polymerase Chain Reaction",
"Receptors, Androgen",
"Severe Combined Immunodeficiency",
"Sex Chromosome Aberrations",
"T-Lymphocytes"... | 1998 | Jun | Carrier identification in X-linked immunodeficiency diseases.
Carrier identification in X-linked immunodeficiency disorders can be based on the demonstration of non-random X inactivation (NRXI) in affected blood cell lineages when growth is impaired in cells expressing the abnormal gene. We examined the utility of seek... |
9,633,978 | eng | [
"D001289",
"Q000188",
"D002606",
"Q000008",
"D002648",
"D002653",
"Q000188",
"Q000453",
"D002675",
"D003000",
"Q000506",
"Q000627",
"D003422",
"D005260",
"D005751",
"D006801",
"D007223",
"D007902",
"D008297",
"D011041",
"Q000453",
"Q000517",
"Q000628",
"D011379",
"D01... | [
"Attention Deficit Disorder with Hyperactivity",
"Charcoal",
"Child",
"Child Behavior Disorders",
"Child, Preschool",
"Clonidine",
"Critical Care",
"Female",
"Gastric Lavage",
"Humans",
"Infant",
"Length of Stay",
"Male",
"Poisoning",
"Prognosis",
"Sympatholytics",
"Tic Disorders"
] | 1998 | Jun | Clonidine poisoning--an emerging problem: epidemiology, clinical features, management and preventative strategies.
To ascertain whether the incidence of clonidine poisoning in children has increased given the probable increase in clonidine use for treatment of childhood behavioural disorders. Cases of clonidine poisoni... |
9,633,980 | eng | [
"D000293",
"D001289",
"Q000188",
"Q000523",
"D001294",
"D000697",
"Q000009",
"Q000627",
"D002648",
"D002675",
"D018592",
"D003913",
"Q000009",
"Q000627",
"D004305",
"D004334",
"D005260",
"D006801",
"D008297",
"D008774",
"Q000009",
"Q000627",
"D010290",
"Q000523",
"D01... | [
"Adolescent",
"Attention Deficit Disorder with Hyperactivity",
"Attitude to Health",
"Central Nervous System Stimulants",
"Child",
"Child, Preschool",
"Cross-Over Studies",
"Dextroamphetamine",
"Dose-Response Relationship, Drug",
"Drug Administration Schedule",
"Female",
"Humans",
"Male",
... | 1998 | Jun | Child and parent perceptions of stimulant medication treatment in attention deficit hyperactivity disorder.
To evaluate child and parent perceptions of treatment with stimulant medication in a sample of children with attention deficit hyperactivity disorder (ADHD). Child and parent perceptions questionnaires were compl... |
9,633,979 | eng | [
"D001921",
"Q000473",
"D001932",
"Q000175",
"Q000235",
"D002648",
"D002675",
"D003952",
"D005260",
"D006338",
"Q000175",
"Q000235",
"D006801",
"D007223",
"D007231",
"D008297",
"D009206",
"Q000473",
"D009460",
"D012640",
"Q000209",
"D014402",
"Q000175",
"Q000235"
] | [
"Brain",
"Brain Neoplasms",
"Child",
"Child, Preschool",
"Diagnostic Imaging",
"Female",
"Heart Neoplasms",
"Humans",
"Infant",
"Infant, Newborn",
"Male",
"Myocardium",
"Neurologic Examination",
"Seizures",
"Tuberous Sclerosis"
] | 1998 | Jun | Cardiac manifestations in tuberous sclerosis: a 10-year review.
Tuberous sclerosis is a genetic disorder with multisystem involvement. The aim of this study was to focus primarily on the cardiac aspects of this condition. This review included 10 children with tuberous sclerosis presenting to our department during a 10-... |
9,633,982 | eng | [
"D016470",
"Q000000981",
"D004292",
"Q000502",
"D004927",
"Q000000981",
"D005066",
"D005260",
"D005317",
"Q000000981",
"D006408",
"Q000000981",
"D006801",
"D006849",
"Q000000981",
"D007231",
"D007235",
"Q000000981",
"D019102",
"D007710",
"Q000000981",
"D007711",
"D018447"... | [
"Bacteremia",
"Dominance, Cerebral",
"Escherichia coli Infections",
"Euthanasia, Passive",
"Female",
"Fetal Growth Retardation",
"Hematoma, Subdural",
"Humans",
"Hydrocephalus",
"Infant, Newborn",
"Infant, Premature, Diseases",
"Infant, Very Low Birth Weight",
"Klebsiella Infections",
"Kle... | 1998 | Jun | Massive subdural haematoma: an unusual complication of septicaemia in preterm very low birthweight infants.
Non-traumatic massive subdural haematoma is a rare condition in newborn infants and is usually associated with hereditary coagulation disorders or congenital vascular malformation. Its occurrence in preterm very ... |
9,633,981 | eng | [
"D002648",
"D003937",
"D006801",
"D006977",
"Q000000981",
"Q000601",
"D008297",
"D009392",
"D014398",
"Q000000981",
"Q000601",
"D014517",
"Q000000981",
"Q000601",
"D014567"
] | [
"Child",
"Diagnosis, Differential",
"Humans",
"Hypertension, Renal",
"Male",
"Nephrectomy",
"Tuberculosis, Renal",
"Ureteral Obstruction",
"Urography"
] | 1998 | Jun | Renal tuberculosis in an Australian-born child.
This report describes a case of renal tuberculosis, complicated by hypertension and ureteric obstruction, in a previously well Australian born child. Despite antituberculous chemotherapy and ureteric stenting, there was a progressive loss of renal function in the right ki... |
9,633,983 | eng | [
"D003937",
"D004900",
"D017707",
"D005260",
"D005500",
"D006452",
"D006801",
"D007223",
"D002546",
"Q000097",
"Q000175",
"Q000628",
"D009460"
] | [
"Diagnosis, Differential",
"Erythroblasts",
"Erythrocyte Transfusion",
"Female",
"Follow-Up Studies",
"Hemoglobinometry",
"Humans",
"Infant",
"Ischemic Attack, Transient",
"Neurologic Examination"
] | 1998 | Jun | Transient erythroblastopenia of childhood associated with transient neurologic deficit: report of a case and review of the literature.
Patients with transient erythroblastopenia of childhood (TEC) may also have a transient neurologic disorder. We present a case history and propose a mechanism for this syndrome. PATIENT... |
9,633,984 | eng | [
"D000592",
"Q000175",
"Q000235",
"Q000652",
"D002547",
"Q000175",
"Q000201",
"Q000235",
"D002675",
"D003937",
"D004421",
"Q000175",
"Q000201",
"Q000235",
"D005260",
"D005977",
"Q000652",
"D050770",
"D006801",
"D007223",
"D008297",
"D008928",
"Q000201",
"D009069",
"Q00... | [
"Amino Acid Metabolism, Inborn Errors",
"Cerebral Palsy",
"Child, Preschool",
"Diagnosis, Differential",
"Dystonia",
"Female",
"Glutarates",
"Glutaryl-CoA Dehydrogenase",
"Humans",
"Infant",
"Male",
"Mitochondria",
"Movement Disorders",
"Oxidoreductases",
"Oxidoreductases Acting on CH-CH... | 1998 | Jun | Glutaric aciduria type 1: an underdiagnosed cause of encephalopathy and dystonia-dyskinesia syndrome in children.
Two cases of glutaric aciduria type 1 (GA 1) are presented. GA 1 is probably underdiagnosed and misdiagnosed, and may explain a proportion of cases of extrapyramidal and 'postencephalitic' cerebral palsy. M... |
9,633,989 | eng | [
"D000900",
"Q000737",
"Q000494",
"D001896",
"Q000737",
"Q000494",
"D004351",
"Q000235",
"D006571",
"Q000737",
"Q000494",
"D009154",
"D013329"
] | [
"Anti-Bacterial Agents",
"Boron Compounds",
"Drug Resistance",
"Heterocyclic Compounds",
"Mutation",
"Structure-Activity Relationship"
] | 1998 | May | Mechanism of action of diazaborines.
The diazaborine family of compounds have antibacterial properties against a range of gram-negative bacteria. Initially, this was thought to be due to the prevention of lipopolysaccharide synthesis. More recently, the molecular target of diazaborines has been identified as the NAD(P)... |
9,633,990 | eng | [
"D019380",
"Q000008",
"Q000494",
"D002986",
"D015224",
"Q000494",
"D004357",
"D004359",
"D004791",
"Q000494",
"D015497",
"Q000187",
"D006801",
"D006918",
"Q000008",
"Q000494",
"D012264",
"Q000037",
"D015215",
"Q000008",
"Q000494"
] | [
"Anti-HIV Agents",
"Clinical Trials as Topic",
"Dideoxynucleosides",
"Drug Synergism",
"Drug Therapy, Combination",
"Enzyme Inhibitors",
"HIV-1",
"Humans",
"Hydroxyurea",
"Ribonucleotide Reductases",
"Zidovudine"
] | 1998 | May | Selective depletion of DNA precursors: an evolving strategy for potentiation of dideoxynucleoside activity against human immunodeficiency virus.
Human immunodeficiency virus type 1 (HIV-1) is wholly dependent on its host cell for a variety of essential metabolites. Among the latter are the deoxynucleoside-5'-triphospha... |
9,633,991 | eng | [
"D000082",
"Q000009",
"Q000493",
"D000818",
"D001189",
"D001711",
"D019392",
"Q000378",
"D065691",
"D051544",
"D065607",
"D003577",
"Q000378",
"D004357",
"D004791",
"Q000494",
"D000431",
"Q000009",
"Q000494",
"D008099",
"Q000187",
"D010089",
"Q000037",
"Q000378",
"D01... | [
"Acetaminophen",
"Animals",
"Aryl Hydrocarbon Hydroxylases",
"Biotransformation",
"Cytochrome P-450 CYP2E1",
"Cytochrome P-450 CYP2E1 Inhibitors",
"Cytochrome P-450 CYP3A",
"Cytochrome P-450 Enzyme Inhibitors",
"Cytochrome P-450 Enzyme System",
"Drug Synergism",
"Enzyme Inhibitors",
"Ethanol",... | 1998 | May | Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.
This commentary focuses on the roles of CYP3A and CYP2E in alcohol-mediated increases in acetaminophen hepatotoxicity. CYP2E has been considered to be the main form of P450 responsible for such toxicity in animals and humans. However, ... |
9,633,992 | eng | [
"D000998",
"Q000494",
"D001483",
"D017931",
"D004259",
"Q000235",
"D004352",
"Q000235",
"D006515",
"Q000187",
"Q000201",
"Q000235",
"D006801",
"D019259",
"Q000494",
"D016297",
"D009154",
"D014407"
] | [
"Antiviral Agents",
"Base Sequence",
"DNA Primers",
"DNA-Directed DNA Polymerase",
"Drug Resistance, Microbial",
"Hepatitis B virus",
"Humans",
"Lamivudine",
"Mutagenesis, Site-Directed",
"Mutation",
"Tumor Cells, Cultured"
] | 1998 | May | Role of additional mutations outside the YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance.
L(-)SddC (3TC) has been shown to be the most promising nucleoside analogue used for the treatment of hepatitis B virus (HBV) infection. Unfortunately, it has been reported that about 12% of HBV-infected pat... |
9,633,993 | eng | [
"D000818",
"D000838",
"D003545",
"Q000031",
"Q000378",
"Q000494",
"D004952",
"D005260",
"D005978",
"Q000031",
"Q000378",
"Q000494",
"D066298",
"D008168",
"Q000187",
"Q000378",
"D051381",
"D017208",
"D013438",
"Q000378",
"D014132",
"Q000187",
"Q000378"
] | [
"Animals",
"Anions",
"Cysteine",
"Esters",
"Female",
"Glutathione",
"In Vitro Techniques",
"Lung",
"Rats",
"Rats, Wistar",
"Sulfhydryl Compounds",
"Trachea"
] | 1998 | May | Elevation of endogenous nucleophiles in rat lung by cysteine and glutathione esters in vitro.
In this study, we have compared the uptake of L-cysteine (L-CySH), D-cysteine (D-CySH), L-cysteine isopropyl ester (L-CIPE) and D-cysteine isopropyl ester (D-CIPE) in rat lung slices and tracheal sections and determined the ef... |
9,633,994 | eng | [
"D000818",
"D003907",
"Q000494",
"D004851",
"Q000037",
"Q000235",
"Q000378",
"D005720",
"D015971",
"Q000187",
"Q000528",
"D005982",
"Q000037",
"Q000235",
"Q000378",
"D008099",
"Q000201",
"Q000473",
"Q000528",
"D008297",
"D051379",
"D008813",
"D011719",
"Q000494",
"D01... | [
"Animals",
"Dexamethasone",
"Epoxide Hydrolases",
"Gamma Rays",
"Gene Expression Regulation, Enzymologic",
"Glutathione Transferase",
"Liver",
"Male",
"Mice",
"Mice, Inbred ICR",
"Pyrazines",
"Radiation-Protective Agents",
"Survival Rate",
"Thiones",
"Thiophenes"
] | 1998 | May | In vivo radioprotective effects of oltipraz in gamma-irradiated mice.
Previous studies in this laboratory have shown that oltipraz (Olt), a chemopreventive agent, enhances radiation(Rad)-inducible glutathione S-transferase (GST) and microsomal epoxide hydrolase (mEH) expression in the liver. The present study was desig... |
9,633,995 | eng | [
"D000085",
"Q000494",
"D002784",
"Q000097",
"D003300",
"Q000097",
"D006801",
"D008077",
"Q000097",
"D018716",
"D007470",
"Q000494",
"D010084",
"D013970",
"Q000494",
"D014280",
"Q000097"
] | [
"Acetates",
"Cholesterol",
"Copper",
"Humans",
"Lipoproteins, LDL",
"Molecular Mimicry",
"Monoiodotyrosine",
"Oxidation-Reduction",
"Thyronines",
"Triglycerides"
] | 1998 | May | Effects of iodotyrosines, thyronines, iodothyroacetic acids and thyromimetic analogues on in vitro copper-induced oxidation of low-density lipoproteins.
We studied the effect of different thyroid compounds [(I2, monoiodo-L-tyrosine (MIT), diiodo-L-tyrosine (DIT), L-thyronine (T0), 3,5-diiodo-L-thyronine (T2), 3,5,3'-tr... |
9,633,996 | eng | [
"D000818",
"D000906",
"Q000276",
"D037263",
"D002478",
"D000431",
"Q000008",
"D007457",
"D008099",
"Q000187",
"Q000378",
"D008297",
"D008985",
"Q000494",
"D011485",
"D011499",
"D051381",
"D017208",
"D011956",
"Q000187",
"Q000276",
"Q000378"
] | [
"Animals",
"Antibodies",
"Asialoglycoprotein Receptor",
"Cells, Cultured",
"Ethanol",
"Iodine Radioisotopes",
"Liver",
"Male",
"Monensin",
"Protein Binding",
"Protein Processing, Post-Translational",
"Rats",
"Rats, Wistar",
"Receptors, Cell Surface"
] | 1998 | May | Differential effects of monensin on asialoglycoprotein receptor function after short-term ethanol administration.
Chronic ethanol consumption is associated with multiple impairments in receptor-mediated endocytosis (RME) by the hepatic asialoglycoprotein receptor (ASGP-R). Previous work on this receptor has shown that ... |
9,633,997 | eng | [
"D000998",
"Q000037",
"Q000097",
"Q000493",
"D001086",
"Q000031",
"Q000037",
"Q000097",
"Q000493",
"D001692",
"D004176",
"Q000494",
"D004912",
"Q000378",
"D005461",
"D006801",
"D009682"
] | [
"Antiviral Agents",
"Arabinofuranosyluracil",
"Biological Transport",
"Dipyridamole",
"Erythrocytes",
"Fluorine",
"Humans",
"Magnetic Resonance Spectroscopy"
] | 1998 | May | 19F NMR study of the uptake of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil in erythrocytes: evidence of transport by facilitated and nonfacilitated pathways.
The 19F NMR resonances of intra- and extracellular 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU) in suspensions of human erythrocytes are well re... |
9,633,998 | eng | [
"D000818",
"D002374",
"Q000494",
"D002478",
"D004247",
"Q000378",
"D015971",
"Q000187",
"D007375",
"Q000494",
"D007700",
"D009131",
"Q000166",
"Q000187",
"Q000201",
"D011451",
"Q000235",
"D012333",
"Q000096",
"Q000235",
"D051381",
"D014157",
"Q000378"
] | [
"Animals",
"Catalase",
"Cells, Cultured",
"DNA",
"Gene Expression Regulation, Enzymologic",
"Interleukin-1",
"Kinetics",
"Muscle, Smooth, Vascular",
"Prostaglandin-Endoperoxide Synthases",
"RNA, Messenger",
"Rats",
"Transcription Factors"
] | 1998 | May | Regulation of cyclo-oxygenase gene expression in rat smooth muscle cells by catalase.
We have studied, in detail, the effect of catalase, one of the naturally occurring antioxidant enzymes, on the expression of cyclo-oxygenase (COX) mRNA and protein in rat aortic smooth muscle cells (RASMC). The activity of COX enzyme ... |
9,633,999 | eng | [
"D000818",
"D000911",
"Q000494",
"D001189",
"D002460",
"D065702",
"D065607",
"D003577",
"Q000378",
"D003975",
"Q000378",
"D006801",
"D008099",
"Q000201",
"D051379",
"D008807",
"D010089",
"Q000037",
"Q000378",
"D010616",
"Q000378",
"D011994",
"Q000037",
"D018411",
"D01... | [
"Animals",
"Antibodies, Monoclonal",
"Aryl Hydrocarbon Hydroxylases",
"Cell Line",
"Cytochrome P-450 CYP2B6",
"Cytochrome P-450 Enzyme Inhibitors",
"Cytochrome P-450 Enzyme System",
"Diazepam",
"Humans",
"Liver",
"Mice",
"Mice, Inbred BALB C",
"Oxidoreductases, N-Demethylating",
"Phenanthr... | 1998 | May | Inhibitory monoclonal antibody to human cytochrome P450 2B6.
The human cytochrome P450 2B6 metabolizes, among numerous other substrates, diazepam, 7-ethoxycoumarin, testosterone, and phenanthrene. A recombinant baculovirus containing the human 2B6 cDNA was constructed and used to express 2B6 in Sf9 insect cells. The 2B... |
9,634,000 | eng | [
"D003470",
"D006150",
"Q000737",
"Q000378",
"D006801",
"D015122",
"Q000378",
"D008727",
"Q000494",
"D008745",
"D013866",
"Q000737",
"D014407"
] | [
"Culture Media",
"Guanine Nucleotides",
"Humans",
"Mercaptopurine",
"Methotrexate",
"Methylation",
"Thioguanine",
"Tumor Cells, Cultured"
] | 1998 | May | Increased concentrations of methylated 6-mercaptopurine metabolites and 6-thioguanine nucleotides in human leukemic cells in vitro by methotrexate.
The effect of methotrexate (MTX) on 6-mercaptopurine (6-MP) metabolism was studied in four human leukemic cell lines in vitro. CCRF-CEM, WI-L2, TBJ, and HL-60 all expressed... |
9,634,001 | eng | [
"D000273",
"Q000187",
"Q000378",
"D000818",
"D001483",
"D022762",
"D004247",
"Q000378",
"D004268",
"Q000037",
"Q000096",
"Q000235",
"D018836",
"Q000494",
"D008099",
"Q000187",
"Q000378",
"D008297",
"D051379",
"D008810",
"D009687",
"Q000037",
"Q000096",
"Q000235",
"D00... | [
"Adipose Tissue",
"Animals",
"Base Sequence",
"CCAAT-Enhancer-Binding Proteins",
"DNA",
"DNA-Binding Proteins",
"Inflammation Mediators",
"Liver",
"Male",
"Mice",
"Mice, Inbred C57BL",
"Nuclear Proteins",
"Polychlorinated Dibenzodioxins",
"Protein Binding",
"RNA, Messenger",
"Receptors... | 1998 | May | Suppression of C/EBPalpha and induction of C/EBPbeta by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse adipose tissue and liver.
We examined the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on two transcription factors, CAAT/enhancer binding protein-alpha (C/EBPalpha) and beta (C/EBPbeta), involved in the coordin... |
9,634,002 | eng | [
"D002999",
"D018076",
"D003854",
"Q000378",
"D019008",
"Q000235",
"D006801",
"D006918",
"Q000494",
"D012333",
"Q000235",
"D012264",
"Q000235",
"D014162",
"D014407"
] | [
"Clone Cells",
"DNA, Complementary",
"Deoxyribonucleotides",
"Drug Resistance, Neoplasm",
"Humans",
"Hydroxyurea",
"RNA, Messenger",
"Ribonucleotide Reductases",
"Transfection",
"Tumor Cells, Cultured"
] | 1998 | May | Determination of deoxyribonucleoside triphosphate pool sizes in ribonucleotide reductase cDNA transfected human KB cells.
Ribonucleotide reductase (RR) is a rate-limiting enzyme in DNA synthesis, which is responsible for controlling deoxyribonucleoside triphosphate (dNTP) pool size. It has been shown that transfection ... |
9,634,003 | eng | [
"D000818",
"D002851",
"D006146",
"Q000008",
"Q000737",
"D007668",
"Q000737",
"D008099",
"Q000737",
"D051379",
"D011732",
"Q000737",
"D012545",
"Q000737"
] | [
"Animals",
"Chromatography, High Pressure Liquid",
"Guanidines",
"Kidney",
"Liver",
"Mice",
"Pyridoxal Phosphate",
"Schiff Bases"
] | 1998 | May | In vivo formation of a Schiff base of aminoguanidine with pyridoxal phosphate.
Aminoguanidine (AG) is considered to be a promising compound for the treatment of diabetic complications. We examined the in vitro and in vivo formation of Schiff bases of AG with pyridoxal 5'-phosphate (PLP) and pyridoxal (PL). AG reacted i... |
9,634,004 | eng | [
"D016475",
"D000225",
"Q000031",
"Q000378",
"D000818",
"D002455",
"Q000187",
"D002460",
"D003513",
"Q000494",
"D004247",
"Q000187",
"Q000378",
"D005472",
"Q000494",
"D006801",
"D051379",
"D019384",
"Q000494",
"D011500",
"Q000494",
"D011687",
"Q000378",
"D012313",
"Q00... | [
"3T3 Cells",
"Adenine",
"Animals",
"Cell Division",
"Cell Line",
"Cycloheximide",
"DNA",
"Fluorouracil",
"Humans",
"Mice",
"Nucleic Acid Synthesis Inhibitors",
"Protein Synthesis Inhibitors",
"Purines",
"RNA"
] | 1998 | May | Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
Activation of purine nucleoside analogs by Escherichia coli purine nucleoside phosphorylase (PNP) is being evaluated as a suicide gene therapy strategy for the treatment of cancer. Because the mechanisms of action of two toxic purine... |
9,634,005 | eng | [
"D000818",
"D000964",
"Q000493",
"D001692",
"D001943",
"Q000378",
"Q000473",
"D002352",
"Q000378",
"D002455",
"Q000187",
"D005492",
"Q000378",
"D006801",
"D008565",
"D026901",
"D008727",
"Q000493",
"D051379",
"D058978",
"D014407"
] | [
"Animals",
"Antimetabolites, Antineoplastic",
"Biological Transport",
"Breast Neoplasms",
"Carrier Proteins",
"Cell Division",
"Folic Acid",
"Humans",
"Membrane Proteins",
"Membrane Transport Proteins",
"Methotrexate",
"Mice",
"Reduced Folate Carrier Protein",
"Tumor Cells, Cultured"
] | 1998 | May | Concentrating capacity of the human reduced folate carrier (hRFC1) in human ZR-75 breast cancer cell lines.
Human RFC1 (hRFC1) transfected in transport-deficient methotrexate MTXR(R)ZR-75-1 human breast carcinoma cells (MTX(R)ZR-75/RFC) were used to investigate the impact of hRFC1 overexpression on influx and concentra... |
9,634,006 | eng | [
"D000081",
"D000970",
"Q000494",
"D004790",
"D004988",
"Q000494",
"D016195",
"Q000187",
"D006801",
"D007527",
"Q000378",
"D008543",
"Q000096",
"D008545",
"Q000235",
"Q000378",
"Q000473",
"D008938",
"Q000187",
"D014442",
"Q000096",
"D010766",
"D011493",
"Q000378",
"D05... | [
"Acetamides",
"Antineoplastic Agents",
"Enzyme Induction",
"Ethers, Cyclic",
"G2 Phase",
"Humans",
"Isoenzymes",
"Melanins",
"Melanoma",
"Mitosis",
"Monophenol Monooxygenase",
"Phosphorylation",
"Protein Kinase C",
"Protein Kinase C-delta",
"Pyrans",
"Spiro Compounds",
"Transcription... | 1998 | May | Stimulation of melanogenesis in a human melanoma cell line by bistratene A.
The polyether toxin, bistratene A, induced morphological and functional differentiation of a human melanoma cell line (MM96E). The cells became blocked at the G2/M transition and elaborated a number of processes. Tyrosinase activity and melanin... |
9,634,007 | eng | [
"D000818",
"D002265",
"Q000378",
"D002478",
"D004791",
"Q000494",
"D004952",
"D006147",
"Q000031",
"Q000737",
"Q000378",
"Q000493",
"D006801",
"D006868",
"D015394",
"D019853",
"Q000037",
"D011355",
"Q000378",
"Q000493",
"D013552",
"D014407"
] | [
"Animals",
"Carboxylic Ester Hydrolases",
"Cells, Cultured",
"Enzyme Inhibitors",
"Esters",
"Guanine",
"Humans",
"Hydrolysis",
"Molecular Structure",
"O(6)-Methylguanine-DNA Methyltransferase",
"Prodrugs",
"Swine",
"Tumor Cells, Cultured"
] | 1998 | May | O6-alkylguanine-DNA alkyltransferase inactivation by ester prodrugs of O6-benzylguanine derivatives and their rate of hydrolysis by cellular esterases.
To modulate the bioavailability and perhaps improve the tumor cell selectivity of O6-alkylguanine-DNA alkyltransferase (AGT) inactivators, pivaloyloxymethyl ester deriv... |
9,634,008 | eng | [
"D017209",
"Q000187",
"D001932",
"Q000201",
"Q000378",
"Q000473",
"D002467",
"Q000378",
"D053938",
"D004791",
"Q000494",
"D005434",
"D018816",
"D005909",
"Q000201",
"Q000378",
"Q000473",
"D006801",
"D007150",
"D007211",
"Q000494",
"D018972",
"Q000096",
"D011493",
"Q00... | [
"Apoptosis",
"Brain Neoplasms",
"Cell Nucleus",
"DNA Fragmentation",
"Enzyme Inhibitors",
"Flow Cytometry",
"Genes, cdc",
"Glioblastoma",
"Humans",
"Immunohistochemistry",
"Indoles",
"Insulin-Like Growth Factor Binding Protein 3",
"Protein Kinase C",
"Tumor Cells, Cultured",
"Tumor Suppr... | 1998 | May | Induction of apoptosis in glioblastoma cells by inhibition of protein kinase C and its association with the rapid accumulation of p53 and induction of the insulin-like growth factor-1-binding protein-3.
Increased protein kinase C(alpha) (PKC(alpha)) expression in glioblastoma cells is associated with proliferation and ... |
9,634,009 | eng | [
"D018938",
"D002463",
"D005960",
"Q000378",
"D006801",
"D007413",
"Q000378",
"D011794",
"Q000378"
] | [
"Caco-2 Cells",
"Cell Membrane Permeability",
"Glucosides",
"Humans",
"Intestinal Mucosa",
"Quercetin"
] | 1998 | May | Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells.
There is mounting evidence from human epidemiological, animal in vivo, and in vitro studies to suggest beneficial effects related to the consumption of quercetin and its glucosides. However, there is limited knowledge on the oral... |
9,634,010 | eng | [
"D000818",
"D001692",
"D002331",
"Q000378",
"D002352",
"Q000378",
"D004195",
"D004622",
"Q000166",
"Q000378",
"D005347",
"Q000378",
"D018628",
"D006579",
"D006720",
"D006801",
"D007700",
"D008052",
"Q000235",
"Q000378",
"D051379",
"D008817"
] | [
"Animals",
"Biological Transport",
"Carnitine",
"Carrier Proteins",
"Disease Models, Animal",
"Embryo, Mammalian",
"Fibroblasts",
"Gene Dosage",
"Heterozygote",
"Homozygote",
"Humans",
"Kinetics",
"Lipid Metabolism, Inborn Errors",
"Mice",
"Mice, Mutant Strains"
] | 1998 | May | Gene-dose effect on carnitine transport activity in embryonic fibroblasts of JVS mice as a model of human carnitine transporter deficiency.
Recently, the marked decline in renal carnitine reabsorption has been thought to account fotr the systemic carnitine deficiency in juvenile visceral steatosis (JVS) mice. We have c... |
9,634,011 | eng | [
"D000544",
"Q000188",
"Q000201",
"D000581",
"Q000037",
"D000818",
"D002800",
"Q000494",
"Q000627",
"D002802",
"Q000378",
"D004593",
"D006801"
] | [
"Alzheimer Disease",
"Amidohydrolases",
"Animals",
"Cholinesterase Inhibitors",
"Cholinesterases",
"Electrophorus",
"Humans"
] | 1998 | May | Inhibition of cholinesterase-associated aryl acylamidase activity by anticholinesterase agents: focus on drugs potentially effective in Alzheimer's disease.
The potency of a series of anticholinesterase (anti-ChE) agents and serotonin-related amines as inhibitors of the aryl acylamidase (AAA) activity associated with e... |
9,634,014 | eng | [
"D000280",
"D000293",
"D000328",
"D002648",
"D002675",
"D003894",
"Q000008",
"Q000009",
"D004305",
"D004775",
"Q000188",
"D005260",
"D006801",
"D008134",
"D008297",
"D012008",
"D012076",
"Q000008",
"Q000009",
"D016896"
] | [
"Administration, Inhalation",
"Adolescent",
"Adult",
"Child",
"Child, Preschool",
"Deamino Arginine Vasopressin",
"Dose-Response Relationship, Drug",
"Enuresis",
"Female",
"Humans",
"Long-Term Care",
"Male",
"Recurrence",
"Renal Agents",
"Treatment Outcome"
] | 1998 | May | Long-term use and tapered dose reduction of intranasal desmopressin in the treatment of enuretic children.
To determine the time taken to achieve complete dryness, the management of desmopressin dosage to reduce the relapse rate, the mean dosage in those responding and any side effects of long-term treatment. Enuretic ... |
9,634,013 | eng | [
"D000284",
"D000293",
"D000328",
"D002648",
"D003894",
"Q000627",
"D004775",
"Q000188",
"D005260",
"D005500",
"D006801",
"D008134",
"D008297",
"D012076",
"Q000627",
"D012890",
"Q000502",
"D011795",
"D016896",
"D001745",
"Q000150"
] | [
"Administration, Oral",
"Adolescent",
"Adult",
"Child",
"Deamino Arginine Vasopressin",
"Enuresis",
"Female",
"Follow-Up Studies",
"Humans",
"Long-Term Care",
"Male",
"Renal Agents",
"Sleep",
"Surveys and Questionnaires",
"Treatment Outcome",
"Urinary Bladder Diseases"
] | 1998 | May | Desmopressin in the treatment of severe nocturnal enuresis in adolescents--a 7-year follow-up study.
To evaluate the role of long-term oral desmopressin (over a 7-year follow-up) in refractory enuretics, particularly in assessing the potential curative effect, and to analyse the results for specific types of patient to... |
9,634,015 | eng | [
"D000293",
"D000328",
"D001285",
"Q000008",
"D002648",
"D003894",
"Q000008",
"D003692",
"D004305",
"D004359",
"D004775",
"Q000188",
"D005260",
"D005500",
"D006801",
"D008297",
"D018727",
"Q000008",
"D012076",
"Q000008",
"D012189",
"D016896"
] | [
"Adolescent",
"Adult",
"Atropine",
"Child",
"Deamino Arginine Vasopressin",
"Delayed-Action Preparations",
"Dose-Response Relationship, Drug",
"Drug Therapy, Combination",
"Enuresis",
"Female",
"Follow-Up Studies",
"Humans",
"Male",
"Muscarinic Antagonists",
"Renal Agents",
"Retrospect... | 1998 | May | Combination therapy in the treatment of persistent nocturnal enuresis.
To evaluate, in a retrospective study, the response rate of older children to combination therapy using a sustained-release anticholinergic agent, hyoscyamine, and a synthetic analogue of antidiuretic hormone, desmopressin acetate. Twenty-eight pati... |
9,634,016 | eng | [
"D000281",
"D000284",
"D000293",
"D001294",
"D002648",
"D003894",
"Q000008",
"D004775",
"Q000188",
"Q000523",
"D005260",
"D006801",
"D008019",
"D008297",
"D010290",
"Q000523",
"D012076",
"Q000008",
"D012649",
"D013315",
"Q000209",
"D016896"
] | [
"Administration, Intranasal",
"Administration, Oral",
"Adolescent",
"Attitude to Health",
"Child",
"Deamino Arginine Vasopressin",
"Enuresis",
"Female",
"Humans",
"Life Style",
"Male",
"Parents",
"Renal Agents",
"Self Concept",
"Stress, Psychological",
"Treatment Outcome"
] | 1998 | May | The effectiveness of desmopressin in the treatment of childhood nocturnal enuresis: predicting response using pretreatment variables.
To determine the factors that predict the effectiveness of desmopressin in the treatment of childhood nocturnal enuresis. Sixty-six children with monosymptomatic nocturnal enuresis were ... |
9,634,019 | eng | [
"D000284",
"D000293",
"D001127",
"Q000097",
"D002648",
"D003894",
"Q000008",
"D015232",
"Q000652",
"D004775",
"Q000097",
"Q000188",
"Q000652",
"D005260",
"D006801",
"D008297",
"D009994",
"D012008",
"D012076",
"Q000008",
"D017211",
"D014554",
"Q000502",
"D014556",
"Q00... | [
"Administration, Oral",
"Adolescent",
"Arginine Vasopressin",
"Child",
"Deamino Arginine Vasopressin",
"Dinoprostone",
"Enuresis",
"Female",
"Humans",
"Male",
"Osmolar Concentration",
"Recurrence",
"Renal Agents",
"Treatment Failure",
"Urination",
"Urine"
] | 1998 | May | Monosymptomatic primary enuresis: differences between patients responding or not responding to oral desmopressin.
To evaluate the 24-h diuresis, urinary osmolality, plasma arginine vasopressin (AVP) and urinary prostaglandin E2 (PGE2) before and during desmopressin treatment in patients with monosymptomatic primary enu... |
9,634,021 | eng | [
"D000293",
"D002648",
"D018680",
"Q000627",
"D003894",
"Q000627",
"D004359",
"D004775",
"Q000097",
"Q000188",
"D005260",
"D006801",
"D008134",
"D008297",
"D008333",
"Q000627",
"D012076",
"Q000627",
"D014667",
"Q000097"
] | [
"Adolescent",
"Child",
"Cholinergic Antagonists",
"Deamino Arginine Vasopressin",
"Drug Therapy, Combination",
"Enuresis",
"Female",
"Humans",
"Long-Term Care",
"Male",
"Mandelic Acids",
"Renal Agents",
"Vasopressins"
] | 1998 | May | Evaluation of antidiuretic hormone before and after long-term treatment with desmopressin in a group of enuretic children.
To determine the effect of long-term desmopressin therapy in enuretic patients on the levels of antidiuretic hormone (ADH) during and after the end of therapy. The study comprised 25 outpatients (1... |
9,634,020 | eng | [
"D000293",
"D017677",
"D002648",
"D002675",
"D004775",
"Q000503",
"D005260",
"D006801",
"D008297",
"D001745",
"Q000503",
"D014554",
"Q000502",
"D014563"
] | [
"Adolescent",
"Age Distribution",
"Child",
"Child, Preschool",
"Enuresis",
"Female",
"Humans",
"Male",
"Urinary Bladder Diseases",
"Urination",
"Urodynamics"
] | 1998 | May | Primary enuresis: a urodynamic evaluation.
To assess urodynamic and clinical data in patients with primary enuresis for potential prognostic indicators of detrusor instability. The records of 33 patients (mean age 8.8 years, range 5-14) with monosymptomatic primary enuresis (MPE, bedwetting as the sole symptom) and 47 ... |
9,634,023 | eng | [
"D001143",
"Q000502",
"D001519",
"D002648",
"D004775",
"Q000523",
"D005260",
"D006801",
"D008297",
"D011602",
"Q000523",
"D012890",
"Q000502",
"D011795"
] | [
"Arousal",
"Behavior",
"Child",
"Enuresis",
"Female",
"Humans",
"Male",
"Psychophysiologic Disorders",
"Sleep",
"Surveys and Questionnaires"
] | 1998 | May | Sleep and night-time behaviour of enuretics and non-enuretics.
To investigate connections between nocturnal enuresis and sleep factors such as the subjective depth of sleep and classical parasomnias. One hundred school children aged 6-10 years answered a questionnaire, with their parents, and the same questions were as... |
9,634,025 | eng | [
"D000553",
"D002648",
"D002675",
"D004775",
"Q000503",
"D006801",
"D007223",
"D007259",
"D011312",
"D013686",
"D001745",
"Q000503",
"D014563"
] | [
"Ambulatory Care",
"Child",
"Child, Preschool",
"Enuresis",
"Humans",
"Infant",
"Infrared Rays",
"Pressure",
"Telemetry",
"Urinary Bladder Diseases",
"Urodynamics"
] | 1998 | May | Continuous real-time ambulatory urodynamic monitoring in infants and young children using infrared telemetry.
To assess the feasibility of continuous real-time ambulatory bladder monitoring in infants and young children using a specially developed ambulatory urodynamic data logger with built-in infrared telemetric on-l... |
9,634,024 | eng | [
"D000293",
"D001143",
"Q000502",
"D002648",
"D003700",
"D004569",
"D004775",
"Q000209",
"Q000503",
"D005260",
"D006801",
"D008297",
"D011602",
"Q000503",
"D012890",
"Q000502"
] | [
"Adolescent",
"Arousal",
"Child",
"Delta Rhythm",
"Electroencephalography",
"Enuresis",
"Female",
"Humans",
"Male",
"Psychophysiologic Disorders",
"Sleep"
] | 1998 | May | Changes in the structure of sleep spindles and delta waves on electroencephalography in patients with nocturnal enuresis.
To evaluate the mechanism of the dysfunction of arousal in patients with Type I and Type IIa enuresis. The numbers of sleep spindles and delta waves were analysed during electroencephalography in 19... |
9,634,026 | eng | [
"D000293",
"D002648",
"D002675",
"D006801",
"D009119",
"D011312",
"D014521",
"Q000002",
"D001745",
"Q000503",
"D014554",
"Q000502",
"D014563"
] | [
"Adolescent",
"Child",
"Child, Preschool",
"Humans",
"Muscle Contraction",
"Pressure",
"Urethra",
"Urinary Bladder Diseases",
"Urination",
"Urodynamics"
] | 1998 | May | Detrusor hypocontractility in children with posterior urethral valves arises before puberty.
To assess prepubertal boys with posterior urethral valves (PUV) using an analysis of pressure-flow studies to evaluate the voiding phase and thus determine if myogenic failure (hypocontractility) arises before puberty and if it... |
9,634,027 | eng | [
"D000293",
"D001294",
"D002648",
"D004775",
"Q000453",
"Q000523",
"D005260",
"D006801",
"D007558",
"Q000453",
"D008297",
"D010290",
"Q000523",
"D015995",
"D012307"
] | [
"Adolescent",
"Attitude to Health",
"Child",
"Enuresis",
"Female",
"Humans",
"Italy",
"Male",
"Parents",
"Prevalence",
"Risk Factors"
] | 1998 | May | An Italian epidemiological multicentre study of nocturnal enuresis.
To estimate the prevalence of enuresis in schoolchildren in Italy. The Italian Club of Nocturnal Enuresis promoted a prevalence study of nocturnal enuresis using a self-administered questionnaire in seven cities in Northern, Central and Southern Italy.... |
9,634,028 | eng | [
"D000293",
"D002648",
"D015331",
"D004327",
"D004739",
"Q000453",
"D004775",
"Q000453",
"Q000209",
"D006801",
"D007845",
"D008137",
"D015995",
"D011446",
"D014549",
"Q000453"
] | [
"Adolescent",
"Child",
"Cohort Studies",
"Drinking Behavior",
"England",
"Enuresis",
"Humans",
"Laughter",
"Longitudinal Studies",
"Prevalence",
"Prospective Studies",
"Urinary Incontinence"
] | 1998 | May | The natural history of urinary symptoms during adolescence.
To determine the prevalence and natural history of urinary symptoms and incontinence among healthy adolescent schoolchildren. A prospective longitudinal study using a confidential questionnaire administered to an original cohort of 1176 local schoolchildren at... |
9,634,029 | eng | [
"D000293",
"D017677",
"D001519",
"D002648",
"D002908",
"D004775",
"Q000453",
"Q000523",
"Q000628",
"D005260",
"D005387",
"Q000453",
"D005500",
"D006801",
"D008297",
"D001523",
"Q000150",
"Q000453",
"D015995"
] | [
"Adolescent",
"Age Distribution",
"Behavior",
"Child",
"Chronic Disease",
"Enuresis",
"Female",
"Finland",
"Follow-Up Studies",
"Humans",
"Male",
"Mental Disorders",
"Prevalence"
] | 1998 | May | A follow-up of enuresis from childhood to adolescence.
To determine the prevalence and treatment of enuresis in a national population-based follow-up study of children aged 8-14 years, to evaluate possible factors that enhance or hamper the attainment of continence and to examine the relationships between enuresis and ... |