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wikidoc
Sertraline detailed information
Sertraline detailed information Sertraline hydrochloride (trade names Zoloft, Lustral) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily used to treat clinical depression in adult outpatients as well as obsessive-c...
Sertraline detailed information Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Sertraline hydrochloride (trade names Zoloft, Lustral) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily used to treat clinical de...
https://www.wikidoc.org/index.php/Sertraline_detailed_information
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wikidoc
Sevelamer (patient information)
Sevelamer (patient information) # Why is this medication prescribed Sevelamer is used to treat high blood levels of phosphorous in patients with kidney disease who are on dialysis. It binds phosphorous that you get from foods in your diet and prevents it from being absorbed into your blood stream. This medication is s...
Sevelamer (patient information) Template:Drug header # Why is this medication prescribed Sevelamer is used to treat high blood levels of phosphorous in patients with kidney disease who are on dialysis. It binds phosphorous that you get from foods in your diet and prevents it from being absorbed into your blood stream...
https://www.wikidoc.org/index.php/Sevelamer_(patient_information)
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wikidoc
Shriners Hospitals for Children
Shriners Hospitals for Children Shriners Hospitals for Children is a network of 22 pediatric non-profit hospitals across North America that provide all care at no charge. # History In 1920 the Imperial Session of the Shriners was held in Portland, Oregon. It was during that session that the membership decided unanimou...
Shriners Hospitals for Children Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shriners Hospitals for Children is a network of 22 pediatric non-profit hospitals across North America that provide all care at no charge. # History In 1920 the Imperial Session of the Shriners was held in Portland, Oregon. It was duri...
https://www.wikidoc.org/index.php/Shriners_Hospitals_for_Children
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wikidoc
Signal-regulatory protein alpha
Signal-regulatory protein alpha Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat m...
Signal-regulatory protein alpha Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat ...
https://www.wikidoc.org/index.php/Signal-regulatory_protein_alpha
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wikidoc
Signal recognition particle RNA
Signal recognition particle RNA The signal recognition particle RNA, (also known as 7SL, 6S, ffs, or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex. SRP recognizes the signal peptide and binds to the ribosome halting protein synthesis. SRP-receptor is a protein that is inbeded in ...
Signal recognition particle RNA The signal recognition particle RNA, (also known as 7SL, 6S, ffs, or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex. SRP recognizes the signal peptide and binds to the ribosome halting protein synthesis. SRP-receptor is a protein that is inbeded in...
https://www.wikidoc.org/index.php/Signal_recognition_particle_RNA
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wikidoc
Silver sulfadiazine description
Silver sulfadiazine description # Descrpition Silver Sulfadiazine Cream is a topical antibacterial preparation which has its active antimicrobial ingredient silver sulfadiazine. The active moiety is contained within an opaque, white, water miscible cream base. Each 1000 grams of Silver Sulfadiazine Cream contains 10 g...
Silver sulfadiazine description Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2] # Descrpition Silver Sulfadiazine Cream is a topical antibacterial preparation which has its active antimicrobial ingredient silver sulfadiazine. The active moiety is contain...
https://www.wikidoc.org/index.php/Silver_sulfadiazine_description
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wikidoc
Sirolimus (patient information)
Sirolimus (patient information) # IMPORTANT WARNING: Sirolimus may increase the risk of infection and lymphoma. If you experience any of the following symptoms, call your doctor immediately: fever, sore throat, chills, frequent or painful urination, or other signs of infection. Keep all appointments with your doctor a...
Sirolimus (patient information) Template:Drug header # IMPORTANT WARNING: Sirolimus may increase the risk of infection and lymphoma. If you experience any of the following symptoms, call your doctor immediately: fever, sore throat, chills, frequent or painful urination, or other signs of infection. Keep all appointme...
https://www.wikidoc.org/index.php/Sirolimus_(patient_information)
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wikidoc
Sister Frances Dominica Ritchie
Sister Frances Dominica Ritchie Sister Frances Dominica Ritchie, FRC is a British nurse, specializing in palliative care. # Early life Though religion was a large part of her upbringing in Edinburgh, where her grandfather was an elder of the Church of Scotland, from the age of three she wanted to be a nurse.. As a chi...
Sister Frances Dominica Ritchie Sister Frances Dominica Ritchie, FRC is a British nurse, specializing in palliative care. # Early life Though religion was a large part of her upbringing in Edinburgh, where her grandfather was an elder of the Church of Scotland, from the age of three she wanted to be a nurse.[1]. As a...
https://www.wikidoc.org/index.php/Sister_Frances_Dominica_Ritchie
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wikidoc
Small Cajal body specific RNA 6
Small Cajal body specific RNA 6 Small Cajal body specific RNA 6 (also known as SCARNA6 or U88) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U5 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs tha...
Small Cajal body specific RNA 6 Template:Rfam box Small Cajal body specific RNA 6 (also known as SCARNA6 or U88) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U5 spliceosomal RNA. scaRNAs are a specific class of small...
https://www.wikidoc.org/index.php/Small_Cajal_body_specific_RNA_6
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wikidoc
Small Cajal body specific RNA 8
Small Cajal body specific RNA 8 Small Cajal body specific RNA 8 (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs tha...
Small Cajal body specific RNA 8 Template:Rfam box Small Cajal body specific RNA 8 (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA. scaRNAs are a specific class of small...
https://www.wikidoc.org/index.php/Small_Cajal_body_specific_RNA_8
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wikidoc
Small intestine cancer
Small intestine cancer overview # Overview In oncology, small intestine cancer, also small bowel cancer and cancer of the small bowel, is a cancer of the small intestine. It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal cancer. Small intestine...
Small intestine cancer overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2] # Overview In oncology, small intestine cancer, also small bowel cancer and cancer of the small bowel, is a cancer of the small intestine. It is relatively rare compared to o...
https://www.wikidoc.org/index.php/Small_intestine_cancer_overview
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wikidoc
Solitary pulmonary nodule x ray
Solitary pulmonary nodule x ray # Overview On conventional radiography, characteristic findings of solitary pulmonary nodule include well-defined, small, and rounded opacities within the pulmonary interstitium, usually 8 mm in diameter and normally surrounded by normal aerated lung. # X Ray - Conventional chest x-ray...
Solitary pulmonary nodule x ray Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] # Overview On conventional radiography, characteristic findings of solitary pulmonary nodule include well-defined, small, and rounded opacities within the pulmonary inter...
https://www.wikidoc.org/index.php/Solitary_pulmonary_nodule_x_ray
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wikidoc
Soluble cell adhesion molecules
Soluble cell adhesion molecules Soluble cell adhesion molecules (sCAMs) are a class of cell adhesion molecule (CAMs - cell surface binding proteins) that may represent important biomarkers for inflammatory processes involving activation or damage to cells such as platelets and the endothelium. They include soluble for...
Soluble cell adhesion molecules Soluble cell adhesion molecules (sCAMs) are a class of cell adhesion molecule (CAMs - cell surface binding proteins) that may represent important biomarkers for inflammatory processes involving activation or damage to cells such as platelets and the endothelium. They include soluble fo...
https://www.wikidoc.org/index.php/Soluble_cell_adhesion_molecules
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wikidoc
Sorafenib (patient information)
Sorafenib (patient information) # Why is this medication prescribed Sorafenib is used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidneys). Sorafenib is in a class of medications called multikinase inhibitors. It works by slowing the spread of cancer cells. # How should this medicine b...
Sorafenib (patient information) Template:Drug header # Why is this medication prescribed Sorafenib is used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidneys). Sorafenib is in a class of medications called multikinase inhibitors. It works by slowing the spread of cancer cells. # How ...
https://www.wikidoc.org/index.php/Sorafenib_(patient_information)
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wikidoc
Specific developmental disorder
Specific developmental disorder # Overview Specific developmental disorders categorizes specific learning disabilities and developmental disorders affecting coordination. # ICD-10 taxonomy The tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) has four cate...
Specific developmental disorder Template:DiseaseDisorder infobox # Overview Specific developmental disorders categorizes specific learning disabilities and developmental disorders affecting coordination. # ICD-10 taxonomy The tenth revision of the International Statistical Classification of Diseases and Related Heal...
https://www.wikidoc.org/index.php/Specific_developmental_disorder
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Spectinomycin adverse reactions
Spectinomycin adverse reactions # Adverse Reactions The following reactions were observed during the single dose clinical trials: soreness at the injection site, urticaria, dizziness, nausea, chills, fever, and insomnia. During multiple dose subchronic tolerance studies in normal human volunteers, the following were n...
Spectinomycin adverse reactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Adverse Reactions The following reactions were observed during the single dose clinical trials: soreness at the injection site, urticaria, dizziness, nausea, chills, fever, and insomnia. During multiple dose subchronic tolerance stud...
https://www.wikidoc.org/index.php/Spectinomycin_adverse_reactions
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Sphingomyelin phosphodiesterase
Sphingomyelin phosphodiesterase Sphingomyelinase phosphodiesterase or simply Sphingomyelinase (SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is found in the lysosomes of both prokaryotic and eukaryotic cells and is responsible for breaking sphingomyelin (SM) down into phosph...
Sphingomyelin phosphodiesterase Sphingomyelinase phosphodiesterase or simply Sphingomyelinase (SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is found in the lysosomes of both prokaryotic and eukaryotic cells and is responsible for breaking sphingomyelin (SM) down into phosp...
https://www.wikidoc.org/index.php/Sphingomyelin_phosphodiesterase
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wikidoc
St. Louis encephalitis
St. Louis encephalitis overview # Overview St. Louis encephalitis is a moderate infection of the central nervous system. St. Louis encephalitis virus is a Group IV positive-sense ssRNA virus within the Flaviviridae family of viruses, and the genus Flavivirus. St. Louis encephalitis virus is closely related to Yellow f...
St. Louis encephalitis overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]; Contributor(s): Irfan Dotani [3], Vishnu Vardhan Serla M.B.B.S. [4] # Overview St. Louis encephalitis is a moderate infection of the central nervous system. St. Louis encephaliti...
https://www.wikidoc.org/index.php/St._Louis_encephalitis_overview
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wikidoc
Stavudine clinical pharmacology
Stavudine clinical pharmacology # Clinical Pharmacology ## Mechanism of Action Stavudine is an antiviral drug. ## Pharmacokinetics The pharmacokinetics of stavudine have been evaluated in HIV-1-infected adult and pediatric patients (Tables 7, 8, and 9). Peak plasma concentrations (Cmax) and area under the plasma con...
Stavudine clinical pharmacology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Clinical Pharmacology ## Mechanism of Action Stavudine is an antiviral drug. ## Pharmacokinetics The pharmacokinetics of stavudine have been evaluated in HIV-1-infected adult an...
https://www.wikidoc.org/index.php/Stavudine_clinical_pharmacology
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wikidoc
Stavudine indications and usage
Stavudine indications and usage # Indications and Usage ZERIT® (stavudine), in combination with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV)-1 infection . ## Dosage and Administration The interval between doses of ZERIT (stavudine) should be 12 hours. ZERIT may be ...
Stavudine indications and usage Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Indications and Usage ZERIT® (stavudine), in combination with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV)-1 infection [see Cl...
https://www.wikidoc.org/index.php/Stavudine_indications_and_usage
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wikidoc
Stony Brook University Hospital
Stony Brook University Hospital Stony Brook University Hospital is a hospital in Stony Brook, New York. A part of the State University of New York at Stony Brook, it is one of the largest hospitals on Long Island. Attached to the Hospital is the Health Sciences Center which houses many research laboratories as well as ...
Stony Brook University Hospital Stony Brook University Hospital is a hospital in Stony Brook, New York. A part of the State University of New York at Stony Brook, it is one of the largest hospitals on Long Island. Attached to the Hospital is the Health Sciences Center which houses many research laboratories as well as...
https://www.wikidoc.org/index.php/Stony_Brook_University_Hospital
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wikidoc
Subcutaneous emphysema
Subcutaneous emphysema overview # Overview Subcutaneous emphysema occurs when gas or air is present in the subcutaneous layer of the skin. Subcutaneous refers to the tissue beneath the cutis of the skin, and emphysema refers to trapped air. Since the air generally comes from the chest cavity, subcutaneous emphysema u...
Subcutaneous emphysema overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Subcutaneous emphysema occurs when gas or air is present in the subcutaneous layer of the skin. Subcutaneous refers to the tissue beneath the cutis of the skin, and emphysema refers to trapped air. Since the air generally c...
https://www.wikidoc.org/index.php/Subcutaneous_emphysema_overview
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Substrate-level phosphorylation
Substrate-level phosphorylation # Overview Substrate-level phosphorylation is a type of chemical reaction that results in the formation of adenosine triphosphate (ATP) by the direct transfer of a phosphate group to adenosine diphosphate (ADP) from a reactive intermediate. In cells, it occurs in the cytoplasm (in glyco...
Substrate-level phosphorylation # Overview Substrate-level phosphorylation is a type of chemical reaction that results in the formation of adenosine triphosphate (ATP) by the direct transfer of a phosphate group to adenosine diphosphate (ADP) from a reactive intermediate. In cells, it occurs in the cytoplasm (in glyco...
https://www.wikidoc.org/index.php/Substrate-level_phosphorylation
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wikidoc
Sucrose box gene transcriptions
Sucrose box gene transcriptions Manual "scanning was also done to identify the presence of sugar responsive elements such as sucrose box (NNAATCA) (Chen et al., 2002; Fillion et al., 1999) and pyrimidine box (CCTTTT, TTTTTTCC) (Washio, 2003)." # Human genes # Gene expressions # Interactions # Consensus sequences Su...
Sucrose box gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff Manual "scanning was also done to identify the presence of sugar responsive elements such as sucrose box (NNAATCA) (Chen et al., 2002; Fillion et al., 1999) and pyrimidine box (CCTTTT, TTTTTTCC) (Washio, 2003)."[1] # Human genes # Gene expr...
https://www.wikidoc.org/index.php/Sucrose_box_gene_transcriptions
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wikidoc
Sucrose gradient centrifugation
Sucrose gradient centrifugation # Overview Sucrose gradient centrifugation is a type of centrifugation often used to purify enveloped viruses (with densities 1.1-1.2 g/cm³) and ribosomes, and also to separate cell organelles from crude cellular extracts. This method is also used to purify exosomes. # Equilibrium cent...
Sucrose gradient centrifugation # Overview Sucrose gradient centrifugation is a type of centrifugation often used to purify enveloped viruses (with densities 1.1-1.2 g/cm³) and ribosomes, and also to separate cell organelles from crude cellular extracts. This method is also used to purify exosomes.[1] # Equilibrium c...
https://www.wikidoc.org/index.php/Sucrose_gradient_centrifugation
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wikidoc
Sunitinib (patient information)
Sunitinib (patient information) # Why is this medication prescribed Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with...
Sunitinib (patient information) Template:Drug header # Why is this medication prescribed Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not tre...
https://www.wikidoc.org/index.php/Sunitinib_(patient_information)
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wikidoc
Superficial parotid lymph nodes
Superficial parotid lymph nodes The superficial parotid lymph nodes are a group of lymph nodes anterior to the ear. Their afferent vessels drain the root of the nose, the eyelids, the frontotemporal region, the external acoustic meatus and the tympanic cavity, possibly also the posterior parts of the palate and the flo...
Superficial parotid lymph nodes Template:Infobox Lymph Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The superficial parotid lymph nodes are a group of lymph nodes anterior to the ear. Their afferent vessels drain the root of the nose, the eyelids, the frontotemporal region, the external acoustic meatus and the t...
https://www.wikidoc.org/index.php/Superficial_parotid_lymph_nodes
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wikidoc
Synchrotron radiation astronomy
Synchrotron radiation astronomy Synchrotron radiation is radiation produced from particles traveling along curved paths near the speed of light. # Radiation "Synchrotron radiation is the electromagnetic radiation emitted when charged particles travel in curved paths. Because in most accelerators the particle trajector...
Synchrotron radiation astronomy Editor-In-Chief: Henry A. Hoff Synchrotron radiation is radiation produced from particles traveling along curved paths near the speed of light. # Radiation "Synchrotron radiation is the electromagnetic radiation emitted when charged particles travel in curved paths. Because in most acc...
https://www.wikidoc.org/index.php/Synchrotron_radiation_astronomy
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TACTAAC box gene transcriptions
TACTAAC box gene transcriptions "A consensus sequence TACTAA(C/T) was derived for the branch site of Dictyostelium introns." # Consensus sequences "The comparison of the two rp51 genes suggests that this homology might be more extensive if one allows up to 3 bases to differ from a larger consensus sequence, ATTTACTAA...
TACTAAC box gene transcriptions Editor-In-Chief: Henry A. Hoff "A consensus sequence TACTAA(C/T) was derived for the branch site of Dictyostelium introns."[1] # Consensus sequences "The comparison of the two rp51 genes [...] suggests that this homology might be more extensive if one allows up to 3 bases to differ fro...
https://www.wikidoc.org/index.php/TACTAAC_box_gene_transcriptions
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wikidoc
Toxic anterior segment syndrome
Toxic anterior segment syndrome Toxic Anterior Segment Syndrome (TASS) is an acute, sterile anterior segment inflammation following generally uneventful cataract and anterior segment surgery. One of the main factors in differentiating TASS from an infectious endophthalmitis is the rapid onset. Most patients with TASS w...
Toxic anterior segment syndrome Toxic Anterior Segment Syndrome (TASS) is an acute, sterile anterior segment inflammation following generally uneventful cataract and anterior segment surgery. One of the main factors in differentiating TASS from an infectious endophthalmitis is the rapid onset. Most patients with TASS ...
https://www.wikidoc.org/index.php/TASS
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Traumatic abdominal wall hernia
Traumatic abdominal wall hernia Synonyms and keywords: TAWH # Overview Traumatic Abdominal Wall Hernia (TAWH) represents an infrequent form of hernia and constitutes 1% of hernia cases. # Historical Perspective The first case was reported by Selby in 1906. # Epidemiology and Demographics There have been 100 cases re...
Traumatic abdominal wall hernia Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-in-Chief: Awni D. Shahait, M.D.[2], The University of Jordan Synonyms and keywords: TAWH # Overview Traumatic Abdominal Wall Hernia (TAWH) represents an infrequent form of hernia and constitutes 1% of hernia cases.[1]...
https://www.wikidoc.org/index.php/TAWH
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Tyrosylprotein sulfotransferase
Tyrosylprotein sulfotransferase Tyrosylprotein sulfotransferase is an enzyme that catalyzes tyrosine sulfation. # Function Tyrosylprotein Sulfotransferase is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. It utilizes 3'-Phosphoadenosine-5'-phosphos...
Tyrosylprotein sulfotransferase Tyrosylprotein sulfotransferase is an enzyme that catalyzes tyrosine sulfation.[1] # Function Tyrosylprotein Sulfotransferase is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. It utilizes 3'-Phosphoadenosine-5'-phos...
https://www.wikidoc.org/index.php/TPST
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Tadalafil (patient information)
Tadalafil (patient information) Why is this medication prescribed== Tadalafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual sti...
Tadalafil (patient information) Template:Drug header Why is this medication prescribed== Tadalafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the p...
https://www.wikidoc.org/index.php/Tadalafil_(patient_information)
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wikidoc
Tamoxifen (patient information)
Tamoxifen (patient information) # IMPORTANT WARNING: Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. These conditions may be serious or fatal. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Also tell your doctor if you smoke...
Tamoxifen (patient information) Template:Drug header # IMPORTANT WARNING: Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. These conditions may be serious or fatal. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Also tell yo...
https://www.wikidoc.org/index.php/Tamoxifen_(patient_information)
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wikidoc
Tamsulosin detailed information
Tamsulosin detailed information # Overview Tamsulosin (rINN) (Template:PronEng) is an α1a-selective alpha blocker used in the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin was developed by Yamanouchi Pharmaceuticals (now part of Astellas Pharma) and is marketed by various companies under lice...
Tamsulosin detailed information Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # For patient information, click here # Overview Tamsulosin (rINN) (Template:PronEng) is an α1a-selective alpha blocker used in the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin was developed by Yamanouchi Ph...
https://www.wikidoc.org/index.php/Tamsulosin_detailed_information
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wikidoc
Tapetum box gene transcriptions
Tapetum box gene transcriptions # Human genes # Consensus sequences The consensus sequence for the TAPETUM box is TCGTGT. # Tapetum box samplings Copying the consensus Tapetum box: TCGTGT and putting the sequence in "⌘F" finds one location between ZNF497 and A1BG and one between ZSCAN22 and A1BG as can be found by t...
Tapetum box gene transcriptions Associate Editor(s)-in-Chief: Henry A. Hoff # Human genes # Consensus sequences The consensus sequence for the TAPETUM box is TCGTGT.[1] # Tapetum box samplings Copying the consensus Tapetum box: TCGTGT and putting the sequence in "⌘F" finds one location between ZNF497 and A1BG and ...
https://www.wikidoc.org/index.php/Tapetum_box_gene_transcriptions
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Tegaserod (patient information)
Tegaserod (patient information) # IMPORTANT WARNING: In some clinical studies, more people who took tegaserod had heart attacks, serious chest pain, or strokes than people who did not take tegaserod. The Food and Drug Administration (FDA) has decided that the benefits of taking tegaserod are not greater than the risk ...
Tegaserod (patient information) Template:Drug header # IMPORTANT WARNING: In some clinical studies, more people who took tegaserod had heart attacks, serious chest pain, or strokes than people who did not take tegaserod. The Food and Drug Administration (FDA) has decided that the benefits of taking tegaserod are not ...
https://www.wikidoc.org/index.php/Tegaserod_(patient_information)
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wikidoc
Telithromycin adverse reactions
Telithromycin adverse reactions # Adverse Reactions In Phase III clinical trials, 4,780 patients (n=2702 in controlled trials) received daily oral doses of KETEK 800 mg once daily for 5 days or 7 to 10 days. Most adverse events were mild to moderate in severity. In the combined Phase III studies, discontinuation due t...
Telithromycin adverse reactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Adverse Reactions In Phase III clinical trials, 4,780 patients (n=2702 in controlled trials) received daily oral doses of KETEK 800 mg once daily for 5 days or 7 to 10 days. Most ad...
https://www.wikidoc.org/index.php/Telithromycin_adverse_reactions
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wikidoc
Telithromycin contraindications
Telithromycin contraindications # contraindications KETEK is contraindicated in patients with myasthenia gravis. Exacerbations of myasthenia gravis have been reported in patients and sometimes occurred within a few hours of the first dose of telithromycin. Reports have included fatal and life-threatening acute respira...
Telithromycin contraindications Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # contraindications KETEK is contraindicated in patients with myasthenia gravis. Exacerbations of myasthenia gravis have been reported in patients and sometimes occurred within a few ...
https://www.wikidoc.org/index.php/Telithromycin_contraindications
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wikidoc
Telithromycin drug interactions
Telithromycin drug interactions # Drug Interactions ## In vitro interactions In vitro studies using a model compound have shown that telithromycin may act as an inhibitor for the hepatic uptake transporters OATP1B1 and OATP1B3. Although the clinical relevance of this finding is unknown, it is possible that concomitan...
Telithromycin drug interactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Drug Interactions ## In vitro interactions In vitro studies using a model compound have shown that telithromycin may act as an inhibitor for the hepatic uptake transporters OATP1B1...
https://www.wikidoc.org/index.php/Telithromycin_drug_interactions
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wikidoc
Temazepam (patient information)
Temazepam (patient information) # IMPORTANT WARNING: FDA notified healthcare professionals of its request that all manufacturers of sedative-hypnotic drug products, a class of drugs used to induce and/or maintain sleep, strengthen their product labeling to include stronger language concerning potential risks. These r...
Temazepam (patient information) Template:Drug header # IMPORTANT WARNING: [Posted 03/14/2007] FDA notified healthcare professionals of its request that all manufacturers of sedative-hypnotic drug products, a class of drugs used to induce and/or maintain sleep, strengthen their product labeling to include stronger lan...
https://www.wikidoc.org/index.php/Temazepam_(patient_information)
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Tenofovir (patient information)
Tenofovir (patient information) # IMPORTANT WARNING: Tenofovir, when used alone or in combination with other antiviral medications, may cause serious damage to the liver and a condition called lactic acidosis. Tell your doctor if you drink large amounts of alcohol and if you have or have ever had liver disease. If you...
Tenofovir (patient information) Template:Drug header # IMPORTANT WARNING: Tenofovir, when used alone or in combination with other antiviral medications, may cause serious damage to the liver and a condition called lactic acidosis. Tell your doctor if you drink large amounts of alcohol and if you have or have ever had...
https://www.wikidoc.org/index.php/Tenofovir_(patient_information)
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wikidoc
Tenofovir clinical pharmacology
Tenofovir clinical pharmacology # Clinical Pharmacology ## Mechanism of Action Tenofovir disoproxil fumarate is an antiviral drug. ## Pharmacokinetics The pharmacokinetics of tenofovir disoproxil fumarate have been evaluated in healthy volunteers and HIV-1 infected individuals. Tenofovir pharmacokinetics are similar...
Tenofovir clinical pharmacology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Clinical Pharmacology ## Mechanism of Action Tenofovir disoproxil fumarate is an antiviral drug. ## Pharmacokinetics The pharmacokinetics of tenofovir disoproxil fumarate have b...
https://www.wikidoc.org/index.php/Tenofovir_clinical_pharmacology
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wikidoc
Tenofovir indications and usage
Tenofovir indications and usage # Indications and Usage ## HIV-1 Infection VIREAD is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older. The following points should be considered when initiating therapy with VIREAD f...
Tenofovir indications and usage Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Indications and Usage ## HIV-1 Infection VIREAD is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients...
https://www.wikidoc.org/index.php/Tenofovir_indications_and_usage
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Terazosin (patient information)
Terazosin (patient information) # Why this medication is prescribed Terazosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary freq...
Terazosin (patient information) Template:Drug header # Why this medication is prescribed Terazosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urina...
https://www.wikidoc.org/index.php/Terazosin_(patient_information)
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wikidoc
The WikiDoc Journal of Medicine
The WikiDoc Journal of Medicine Wiki Doc now supports one of the first open access journals in medicine. We invite you to submit a manuscript. # What is an Open Access Journal? An Open Access Journal has the following advantages over traditional print journals and articles: - It is freely accessible via the Internet -...
The WikiDoc Journal of Medicine Wiki Doc now supports one of the first open access journals in medicine. We invite you to submit a manuscript. # What is an Open Access Journal? An Open Access Journal has the following advantages over traditional print journals and articles: - It is freely accessible via the Internet ...
https://www.wikidoc.org/index.php/The_WikiDoc_Journal_of_Medicine
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wikidoc
The heart in cocaine dependence
The heart in cocaine dependence Cocaine can cause coronary artery spasms which may lead to a myocardial infarction. This effect can happen randomly to any user. The coronary artery spasms can occur on the user's first usage or any other usage after. The coronary spasms cause the ectopic ventricular foci of the heart to...
The heart in cocaine dependence Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Cocaine can cause coronary artery spasms which may lead to a myocardial infarction. This effect can happen randomly to any user. The coronary artery spasms can occur on the user's first usage or any other usage after. The coronary spasm...
https://www.wikidoc.org/index.php/The_heart_in_cocaine_dependence
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wikidoc
Treatment of multiple sclerosis
Treatment of multiple sclerosis # Background Although there is no known cure for multiple sclerosis (MS), several therapies for multiple sclerosis have proven helpful. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS). The most common initial course of th...
Treatment of multiple sclerosis Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editors-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] # Background Although there is no known cure for multiple sclerosis (MS), several therapies for multiple sclerosis have proven helpful. Multiple sclerosis is a chronic inflamma...
https://www.wikidoc.org/index.php/Therapies_for_multiple_sclerosis
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wikidoc
Thiabendazole adverse reactions
Thiabendazole adverse reactions # Adverse Reactions - Gastrointestinal: anorexia, nausea, vomiting, diarrhea, epigastric distress, abdominal pain, jaundice, cholestasis, parenchymal liver damage and hepatic failure. (See WARNINGS.) - Central Nervous System: dizziness, weariness, drowsiness, giddiness, headache, numbne...
Thiabendazole adverse reactions Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Adverse Reactions - Gastrointestinal: anorexia, nausea, vomiting, diarrhea, epigastric distress, abdominal pain, jaundice, cholestasis, parenchymal liver damage and hepatic failure. (See WARNINGS.) - Central Nervous System: dizziness...
https://www.wikidoc.org/index.php/Thiabendazole_adverse_reactions
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wikidoc
Tiagabine (patient information)
Tiagabine (patient information) # Why is this medication prescribed Tiagabine is used in combination with other medications to treat partial seizures (a type of epilepsy). Tiagabine is in a class of medications called anticonvulsants. It is not known exactly how tiagabine works, but it increases the amount of natural ...
Tiagabine (patient information) Template:Drug header # Why is this medication prescribed Tiagabine is used in combination with other medications to treat partial seizures (a type of epilepsy). Tiagabine is in a class of medications called anticonvulsants. It is not known exactly how tiagabine works, but it increases ...
https://www.wikidoc.org/index.php/Tiagabine_(patient_information)
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wikidoc
Tissue factor pathway inhibitor
Tissue factor pathway inhibitor Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, d...
Tissue factor pathway inhibitor Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, ...
https://www.wikidoc.org/index.php/Tissue_factor_pathway_inhibitor
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wikidoc
Tocainide (patient information)
Tocainide (patient information) # IMPORTANT WARNING Tocainide is no longer available in the United States. If you are currently taking tocainide, you should call your doctor to discuss switching to another treatment. Tocainide may cause bone marrow suppression which will prevent your body from making blood cells; be s...
Tocainide (patient information) Template:Drug header # IMPORTANT WARNING Tocainide is no longer available in the United States. If you are currently taking tocainide, you should call your doctor to discuss switching to another treatment. Tocainide may cause bone marrow suppression which will prevent your body from ma...
https://www.wikidoc.org/index.php/Tocainide_(patient_information)
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Tolcapone (patient information)
Tolcapone (patient information) # IMPORTANT WARNING: Tolcapone may cause life threatening liver damage. Tell your doctor if you have or have ever had liver disease. Keep all appointments with your doctor and the laboratory. Your doctor will order certain laboratory tests before and during treatment to check your respo...
Tolcapone (patient information) Template:Drug header # IMPORTANT WARNING: Tolcapone may cause life threatening liver damage. Tell your doctor if you have or have ever had liver disease. Keep all appointments with your doctor and the laboratory. Your doctor will order certain laboratory tests before and during treatme...
https://www.wikidoc.org/index.php/Tolcapone_(patient_information)
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wikidoc
Tolvaptan (patient information)
Tolvaptan (patient information) # Why is this medication prescribed? Tolvaptan is used to increase low levels of sodium in the blood in people who have heart failure (condition in which the heart cannot pump enough blood to all parts of the body), syndrome of inappropriate antidiuretic hormone (SIADH; condition in whi...
Tolvaptan (patient information) Template:Drug header # Why is this medication prescribed? Tolvaptan is used to increase low levels of sodium in the blood in people who have heart failure (condition in which the heart cannot pump enough blood to all parts of the body), syndrome of inappropriate antidiuretic hormone (S...
https://www.wikidoc.org/index.php/Tolvaptan_(patient_information)
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wikidoc
Transverse intermuscular septum
Transverse intermuscular septum # Overview The deep transverse fascia of the leg (or transverse intermuscular septum) is a transversely placed, intermuscular septum, between the superficial and deep muscles of the back of the leg. At the sides it is connected to the margins of the tibia and fibula. Above, where it cov...
Transverse intermuscular septum Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The deep transverse fascia of the leg (or transverse intermuscular septum)[1] is a transversely placed, intermuscular septum, between the superficial and deep muscles of the back of the leg. At the s...
https://www.wikidoc.org/index.php/Transverse_intermuscular_septum
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wikidoc
Traumatic brain injury
Traumatic brain injury overview # Overview Traumatic brain injury (TBI) occurs when physical trauma causes brain damage. TBI can result from a blunt head trauma or a penetrating head injury and is one of two subsets of acquired brain injury (ABI). The other subset is non-traumatic brain injury, or injuries that do no...
Traumatic brain injury overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Deekshitha Manney, M.D.[[2]] Joanna Ekabua, M.D. [3] # Overview Traumatic brain injury (TBI) occurs when physical trauma causes brain damage. TBI can result from a blunt head trauma or a penetrating head ...
https://www.wikidoc.org/index.php/Traumatic_brain_injury_overview
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wikidoc
Trazodone (patient information)
Trazodone (patient information) # IMPORTANT WARNING: Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as trazodone may be more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressants. Children younger th...
Trazodone (patient information) Template:Drug header # IMPORTANT WARNING: Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as trazodone may be more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressant...
https://www.wikidoc.org/index.php/Trazodone_(patient_information)
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wikidoc
Treatment of ulcerative colitis
Treatment of ulcerative colitis # Overview This article concerns the treatment of ulcerative colitis, a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the co...
Treatment of ulcerative colitis # Overview This article concerns the treatment of ulcerative colitis, a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the co...
https://www.wikidoc.org/index.php/Treatment_of_ulcerative_colitis
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Triazolam (patient information)
Triazolam (patient information) # IMPORTANT WARNING: FDA notified healthcare professionals of its request that all manufacturers of sedative-hypnotic drug products, a class of drugs used to induce and/or maintain sleep, strengthen their product labeling to include stronger language concerning potential risks. These r...
Triazolam (patient information) Template:Drug header # IMPORTANT WARNING: [Posted 03/14/2007] FDA notified healthcare professionals of its request that all manufacturers of sedative-hypnotic drug products, a class of drugs used to induce and/or maintain sleep, strengthen their product labeling to include stronger lan...
https://www.wikidoc.org/index.php/Triazolam_(patient_information)
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wikidoc
Triple-S Management Corporation
Triple-S Management Corporation Triple-S Management Corporation, more commonly known simply as Triple-S, Triple SSS, or SSS, is a financial holding company located in San Juan, Puerto Rico which offers a wide range of insurance products and services in Puerto Rico through its wholly-owned subsidiaries. Founded on 1959,...
Triple-S Management Corporation Template:Infobox Company Triple-S Management Corporation, more commonly known simply as Triple-S, Triple SSS, or SSS, is a financial holding company located in San Juan, Puerto Rico which offers a wide range of insurance products and services in Puerto Rico through its wholly-owned subs...
https://www.wikidoc.org/index.php/Triple-S_Management_Corporation
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wikidoc
Trousseau sign of latent tetany
Trousseau sign of latent tetany # Overview Trousseau sign of latent tetany is a medical sign observed in patients with low calcium. This sign may become positive before other gross manifestations of hypocalcemia such as hyperreflexia and tetany, as such it is generally believed to be more sensitive (94%) than the Chvo...
Trousseau sign of latent tetany Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Trousseau sign of latent tetany is a medical sign observed in patients with low calcium.[1] This sign may become positive before other gross manifestations of hypocalcemia such as hyperreflexia and tetany, a...
https://www.wikidoc.org/index.php/Trousseau%27s_sign_of_latent_tetany
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wikidoc
Tuberculous meningitis
Tuberculous meningitis overview # Overview Tuberculous meningitis is Mycobacterium tuberculosis infection of the meninges. It is the most common form of CNS tuberculosis. # Causes Tuberculous meningitis is caused by Mycobacterium tuberculosis, the bacteria that causes tuberculosis. The bacteria spreads to the brain ...
Tuberculous meningitis overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Tuberculous meningitis is Mycobacterium tuberculosis infection of the meninges. It is the most common form of CNS tuberculosis. # Causes Tuberculous meningitis is caused by Mycobacterium tuberculosis, the bacteria that cau...
https://www.wikidoc.org/index.php/Tuberculous_meningitis_overview
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wikidoc
Union of South American Nations
Union of South American Nations The Union of South American Nations (Template:Lang-nl, Template:Lang-pt, Template:Lang-es, and abbreviated as Unasur and Unasul) is a fledgling supranational and intergovernmental union that will unite two existing free-trade organizations – Mercosur and the Andean Community – as part o...
Union of South American Nations Template:Infobox Geopolitical organization The Union of South American Nations (Template:Lang-nl, Template:Lang-pt, Template:Lang-es, and abbreviated as Unasur and Unasul) is a fledgling supranational and intergovernmental union that will unite two existing free-trade organizations – M...
https://www.wikidoc.org/index.php/USAN
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wikidoc
USMLE Step 2 Clinical Knowledge
USMLE Step 2 Clinical Knowledge The USMLE-Step 2-CK ("Clinical Knowledge") is the multiple-choice portion of the second part of the United States Medical Licensure Examination. Assesses clinical knowledge through a traditional, multiple-choice examination. In contrast to the USMLE Step 1, the focus is much more on clin...
USMLE Step 2 Clinical Knowledge Template:Physician education and training in the United States The USMLE-Step 2-CK ("Clinical Knowledge") is the multiple-choice portion of the second part of the United States Medical Licensure Examination. Assesses clinical knowledge through a traditional, multiple-choice examination....
https://www.wikidoc.org/index.php/USMLE_Step_2_Clinical_Knowledge
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wikidoc
Ultraviolet radiation astronomy
Ultraviolet radiation astronomy Ultraviolet astronomy is radiation astronomy applied to the ultraviolet phenomena of the sky, especially at night. It is also conducted above the Earth's atmosphere and at locations away from the Earth as a part of explorational (or exploratory) ultraviolet astronomy. Acquiring a suntan ...
Ultraviolet radiation astronomy Editor-In-Chief: Henry A. Hoff Ultraviolet astronomy is radiation astronomy applied to the ultraviolet phenomena of the sky, especially at night. It is also conducted above the Earth's atmosphere and at locations away from the Earth as a part of explorational (or exploratory) ultraviole...
https://www.wikidoc.org/index.php/Ultraviolet_radiation_astronomy
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wikidoc
University of California, Davis
University of California, Davis The University of California, Davis, commonly known as UC Davis, is one of the ten campuses of the University of California, and was established as the University Farm in 1905. It was formally established as a general UC campus by the Regents of the University of California in 1959. UC D...
University of California, Davis Template:Infobox University The University of California, Davis, commonly known as UC Davis, is one of the ten campuses of the University of California, and was established as the University Farm in 1905. It was formally established as a general UC campus by the Regents of the Universit...
https://www.wikidoc.org/index.php/University_of_California,_Davis
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wikidoc
Unstable angina pathophysiology
Unstable angina pathophysiology # Overview Unstable angina occurs when myocardial oxygen demand exceeds myocardial oxygen supply at rest or with minimal exertion. This supply/demand mismatch can be caused by conditions that increase oxygen demand or reduce oxygen supply. # Pathophysiology Unstable angina occurs when ...
Unstable angina pathophysiology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S. # Overview Unstable angina occurs when myocardial oxygen demand exceeds myocardial oxygen supply at rest or with min...
https://www.wikidoc.org/index.php/Unstable_angina_pathophysiology
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wikidoc
Ureaplasma urealyticum
Ureaplasma urealyticum overview # Overview Ureaplasma species (U. urealyticum and U. parvum) are commensal organisms commonly found in the urogenital tract of sexually active men and women. These organisms are considered to be of low virulence although several studies have demonstrated an association between vaginal c...
Ureaplasma urealyticum overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2] # Overview Ureaplasma species (U. urealyticum and U. parvum) are commensal organisms commonly found in the urogenital tract of sexually active men and women.[1] These organisms ...
https://www.wikidoc.org/index.php/Ureaplasma_urealyticum_overview
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wikidoc
Vesicular monoamine transporter
Vesicular monoamine transporter # Overview The vesicular monoamine transporter is a transport protein located within the presynaptic cell. # Isoforms It comprises the two isoforms: - VMAT1 - VMAT2 # Substrates Substrates for the transporter is mainly noradrenaline, adrenaline and isoprenaline. However, other substra...
Vesicular monoamine transporter Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Template:Editor help # Overview The vesicular monoamine transporter is a transport protein located within the presynaptic cell. # Isoforms It comprises the two isoforms: - VMAT1 - VMAT2 # Substrates Substrates for the transporter is ...
https://www.wikidoc.org/index.php/VMAT
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wikidoc
V and P box gene transcriptions
V and P box gene transcriptions "REV-ERBα and RORa are nuclear receptors rather than bZIP transcription factors like VRI and PDP1ϵ, and they regulate transcription by binding RORE elements rather than V/P-boxes (Bell-Pedersen et al., 2005)." "A delayed accumulation of PDP1 leads to a replacement of VRI from P/V (PDP1 ...
V and P box gene transcriptions Editor-In-Chief: Henry A. Hoff "REV-ERBα and RORa are nuclear receptors rather than bZIP transcription factors like VRI [target gene: vrille (VRI)] and PDP1ϵ, and they regulate transcription by binding RORE elements rather than V/P-boxes (Bell-Pedersen et al., 2005)."[1] "A delayed accu...
https://www.wikidoc.org/index.php/V_and_P_box_gene_transcriptions
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wikidoc
Vaginitis (patient information)
Vaginitis (patient information) For the WikiDoc page for this topic, click here # Overview Vaginitis is inflammation or infection of the vagina. # What are the symptoms of Vaginitis? - Irritation and itching of the genital area - Inflammation (irritation, redness, and swelling) of the labia majora, labia minora, or p...
Vaginitis (patient information) For the WikiDoc page for this topic, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Vaginitis is inflammation or infection of the vagina. # What are the symptoms of Vaginitis? - Irritation and itching of the genital area - Inflammation (irritation, redness, a...
https://www.wikidoc.org/index.php/Vaginitis_(patient_information)
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wikidoc
Valsartan (patient information)
Valsartan (patient information) # IMPORTANT WARNING: Do not take valsartan if you are pregnant. If you become pregnant while taking valsartan, call your doctor immediately. Valsartan may harm the fetus. # Why is this medication prescribed Valsartan is used alone or in combination with other medications to treat high ...
Valsartan (patient information) Template:Drug header # IMPORTANT WARNING: Do not take valsartan if you are pregnant. If you become pregnant while taking valsartan, call your doctor immediately. Valsartan may harm the fetus. # Why is this medication prescribed Valsartan is used alone or in combination with other medi...
https://www.wikidoc.org/index.php/Valsartan_(patient_information)
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wikidoc
Ventricular remodeling
Ventricular remodeling overview Synonyms and keywords: Left ventricular remodeling; LV remodeling # Overview Ventricular remodeling refers to the changes in size, shape, and function of the heart after injury to the left ventricle. The injury is typically due to acute myocardial infarction (usually transmural or ST s...
Ventricular remodeling overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: Left ventricular remodeling; LV remodeling # Overview Ventricular remodeling refers to the changes in size, shape, and function of the heart after injury to the left ventricle. The injury is typically due to acu...
https://www.wikidoc.org/index.php/Ventricular_remodeling_overview
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wikidoc
Verapamil (patient information)
Verapamil (patient information) # Why this medication is prescribed Verapamil is used to treat irregular heartbeats (arrhythmias) and high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart to control chest pain (angi...
Verapamil (patient information) Template:Drug header # Why this medication is prescribed Verapamil is used to treat irregular heartbeats (arrhythmias) and high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart to co...
https://www.wikidoc.org/index.php/Verapamil_(patient_information)
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wikidoc
Visceral leishmaniasis
Visceral leishmaniasis overview # Overview Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, a disease caused by parasites of the Leishmania genus. It is the second-largest parasitic killer in the world (after malaria), responsible for an estimated 60 000 who die from the disease each year out of ...
Visceral leishmaniasis overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, a disease caused by parasites of the Leishmania genus. It is the second-largest parasitic killer in the world (after malaria), responsible for an estimat...
https://www.wikidoc.org/index.php/Visceral_leishmaniasis_overview
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wikidoc
Vitamin B12 deficiency
Vitamin B12 deficiency overview # Overview B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system. The daily cobalamin (vitamin B12) requirement is 1-2 mcg. An intake of 5-20 mcg/day is usual in a Western diet. The total body can store 2-5 mg. 60% of vitamin B1...
Vitamin B12 deficiency overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system. The daily cobalamin (vitamin B12) requirement is 1-2 mcg. An intake of 5-20 mcg/day is usual in a Western diet...
https://www.wikidoc.org/index.php/Vitamin_B12_deficiency_overview
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Vitamin D deficiency prevention
Vitamin D deficiency prevention # Overview Vitamin D is recommended for everyone to prevent vitamin D deficiency. The current guideline by the Institute of Medicine (IOM) recommends 600 IU/d for healthy individuals between 1-70 years of age and 800 IU/d for elderly over 70. # Prevention Effective measures for the pri...
Vitamin D deficiency prevention Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2] # Overview Vitamin D is recommended for everyone to prevent vitamin D deficiency. The current guideline by the Institute of Medicine (IOM) recommends 600 IU/d for healthy individual...
https://www.wikidoc.org/index.php/Vitamin_D_deficiency_prevention
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wikidoc
Voltage-gated potassium channel
Voltage-gated potassium channel Voltage-gated potassium channels are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential. They play a crucial role during action potentials in returning the depolarized cell to a resting state. # Classification ## Alpha subuni...
Voltage-gated potassium channel Voltage-gated potassium channels are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential. They play a crucial role during action potentials in returning the depolarized cell to a resting state. # Classification ## Alpha subun...
https://www.wikidoc.org/index.php/Voltage-gated_potassium_channel
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wikidoc
Von Willebrand disease
Von Willebrand disease overview # Overview Von Willebrand’s disease is an genetic coagulation disorder with resultant abnormality in platelet adhesion and aggregation. Von Willebrand disease (vWD) is the most common genetic coagulation disorder described in humans. It affects up to 1% of the population, although most...
Von Willebrand disease overview Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2] Nazia Fuad M.D. # Overview Von Willebrand’s disease is an genetic coagulation disorder with resultant abnormality in platelet adhesion and aggregation. Von Willebrand di...
https://www.wikidoc.org/index.php/Von_Willebrand_disease_overview
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wikidoc
WD repeat-containing protein 11
WD repeat-containing protein 11 WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by the WDR11 gene. # Function This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of app...
WD repeat-containing protein 11 WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by the WDR11 gene.[1][2][3] # Function This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regi...
https://www.wikidoc.org/index.php/WD_repeat-containing_protein_11
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wikidoc
Walter Reed Army Medical Center
Walter Reed Army Medical Center The Walter Reed National Army Medical Center (WRAMC) is the United States Army's medical center on the east coast of the United States. Located on 113 acres (457,000 m²) in Washington, D.C., it serves more than 150,000 active and retired personnel from all branches of the military. The c...
Walter Reed Army Medical Center Template:Two other uses Template:Infobox Military Unit The Walter Reed National Army Medical Center (WRAMC) is the United States Army's medical center on the east coast of the United States. Located on 113 acres (457,000 m²) in Washington, D.C., it serves more than 150,000 active and re...
https://www.wikidoc.org/index.php/Walter_Reed_Army_Medical_Center
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wikidoc
Zanamivir clinical pharmacology
Zanamivir clinical pharmacology # Clinical Pharmacology Absorption and Bioavailability: Pharmacokinetic studies of orally inhaled zanamivir indicate that approximately 4% to 17% of the inhaled dose is systemically absorbed. The peak serum concentrations ranged from 17 to 142 ng/mL within 1 to 2 hours following a 10 mg...
Zanamivir clinical pharmacology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Clinical Pharmacology Absorption and Bioavailability: Pharmacokinetic studies of orally inhaled zanamivir indicate that approximately 4% to 17% of the inhaled dose is systemically a...
https://www.wikidoc.org/index.php/Zanamivir_clinical_pharmacology
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wikidoc
Zanamivir indications and usage
Zanamivir indications and usage # Indications and Usage ## Treatment of Influenza RELENZA® (zanamivir) Inhalation Powder is indicated for treatment of uncomplicated acute illness due to influenza A and B virus in adults and pediatric patients aged 7 years and older who have been symptomatic for no more than 2 days. ...
Zanamivir indications and usage Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Indications and Usage ## Treatment of Influenza RELENZA® (zanamivir) Inhalation Powder is indicated for treatment of uncomplicated acute illness due to influenza A and B virus in a...
https://www.wikidoc.org/index.php/Zanamivir_indications_and_usage
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wikidoc
Zazam Sheriff Phillips syndrome
Zazam Sheriff Phillips syndrome # Overview Zazam Sheriff Phillips syndrome is a rare genetically congenital syndrome. It is associated with the symptoms of Aniridia, ectopia lentis, abnormal upper incisors and mental retardation. It is believed to be inherited in an autosomal recessive fashion. Not a lot of research h...
Zazam Sheriff Phillips syndrome # Overview Zazam Sheriff Phillips syndrome is a rare[1] genetically congenital syndrome. It is associated with the symptoms of Aniridia, ectopia lentis, abnormal upper incisors and mental retardation.[2] It is believed to be inherited in an autosomal recessive fashion. Not a lot of rese...
https://www.wikidoc.org/index.php/Zazam_Sheriff_Phillips_syndrome
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1998 Klang Valley water crisis
1998 Klang Valley water crisis The 1998 Klang Valley water crisis occurred in Malaysia in February 1998 when the three reservoir dams in Klang Valley, Klang Gates Dam, Batu Dam and Semenyih Dam suffered a substantial drop in water level following the El Niño phenomenon. The subsequent water shortage affected almost all...
1998 Klang Valley water crisis The 1998 Klang Valley water crisis occurred in Malaysia in February 1998 when the three reservoir dams in Klang Valley, Klang Gates Dam, Batu Dam and Semenyih Dam suffered a substantial drop in water level following the El Niño phenomenon. The subsequent water shortage affected almost al...
https://www.wikidoc.org/index.php/1998_Klang_Valley_water_crisis
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wikidoc
Methylglutaconyl-CoA hydratase
Methylglutaconyl-CoA hydratase 3-Methylglutaconyl-CoA hydratase, also known as MG-CoA hydratase and AUH, is an enzyme encoded by the AUH gene on chromosome 19. It is a member of the enoyl-CoA hydratase/isomerase superfamily, but it is the only member of that family that is able to bind to RNA. Not only does it bind to ...
Methylglutaconyl-CoA hydratase 3-Methylglutaconyl-CoA hydratase, also known as MG-CoA hydratase and AUH, is an enzyme encoded by the AUH gene on chromosome 19. It is a member of the enoyl-CoA hydratase/isomerase superfamily, but it is the only member of that family that is able to bind to RNA. Not only does it bind to...
https://www.wikidoc.org/index.php/3-_Methylglutaconic_aciduria_type_3
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wikidoc
3-dehydrosphinganine reductase
3-dehydrosphinganine reductase 3-dehydrosphinganine reductase (EC 1.1.1.102) also known as 3-ketodihydrosphingosine reductase (KDSR) or follicular variant translocation protein 1 (FVT1) is an enzyme that in humans is encoded by the KDSR gene. # Function 3-dehydrosphinganine reductase catalyzes the chemical reaction: T...
3-dehydrosphinganine reductase 3-dehydrosphinganine reductase (EC 1.1.1.102) also known as 3-ketodihydrosphingosine reductase (KDSR) or follicular variant translocation protein 1 (FVT1) is an enzyme that in humans is encoded by the KDSR gene.[1][2][3][4][5] # Function 3-dehydrosphinganine reductase catalyzes the chem...
https://www.wikidoc.org/index.php/3-dehydrosphinganine_reductase
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wikidoc
Methylcrotonyl-CoA carboxylase
Methylcrotonyl-CoA carboxylase Methylcrotonyl CoA carboxylase (MCC) (3-methylcrotonyl CoA carboxylase, methylcrotonoyl-CoA carboxylase) is a biotin-requiring enzyme located in the mitochondria. MCC uses bicarbonate as a carboxyl group source to catalyze the carboxylation of a carbon adjacent to a carbonyl group perform...
Methylcrotonyl-CoA carboxylase Methylcrotonyl CoA carboxylase (MCC) (3-methylcrotonyl CoA carboxylase, methylcrotonoyl-CoA carboxylase) is a biotin-requiring enzyme located in the mitochondria. MCC uses bicarbonate as a carboxyl group source to catalyze the carboxylation of a carbon adjacent to a carbonyl group perfor...
https://www.wikidoc.org/index.php/3-methylcrotonyl-CoA_carboxylase
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wikidoc
Phosphogluconate dehydrogenase
Phosphogluconate dehydrogenase 6-Phosphogluconate dehydrogenase (6PGD) is an enzyme in the pentose phosphate pathway. It forms ribulose 5-phosphate from 6-phosphogluconate. It is an oxidative carboxylase that catalyses the decarboxylating reduction of 6-phosphogluconate into ribulose 5-phosphate in the presence of NADP...
Phosphogluconate dehydrogenase 6-Phosphogluconate dehydrogenase (6PGD) is an enzyme in the pentose phosphate pathway. It forms ribulose 5-phosphate from 6-phosphogluconate. It is an oxidative carboxylase that catalyses the decarboxylating reduction of 6-phosphogluconate into ribulose 5-phosphate in the presence of NAD...
https://www.wikidoc.org/index.php/6-phosphogluconate_dehydrogenase
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wikidoc
7-Dehydrocholesterol reductase
7-Dehydrocholesterol reductase 7-Dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the DHCR7 gene. # Function The protein encoded by this gene is an enzyme catalyzing the production of cholesterol from 7-Dehydrocholesterol using NADPH. The DHCR7 gene encodes delta-7-sterol re...
7-Dehydrocholesterol reductase 7-Dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the DHCR7 gene.[1][2][3] # Function The protein encoded by this gene is an enzyme catalyzing the production of cholesterol from 7-Dehydrocholesterol using NADPH. The DHCR7 gene encodes delta-7...
https://www.wikidoc.org/index.php/7-Dehydrocholesterol_reductase
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wikidoc
ADHD predominantly inattentive
ADHD predominantly inattentive # Overview ADHD predominantly inattentive (ADHD-I or ADHD-PI) is one of the three subtypes of Attention-Deficit Hyperactivity Disorder (ADHD). While ADHD-PI is commonly referred to as Attention Deficit Disorder (ADD) without hyperactivity, the terms "ADD" and "attention-deficit disorder"...
ADHD predominantly inattentive Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] # Overview ADHD predominantly inattentive (ADHD-I or ADHD-PI) is one of the three subtypes of Attention-Deficit Hyperactivity Disorder (ADHD). While ADHD-PI is commonly referred to as Attention Deficit Disorder (ADD) without hyperactivi...
https://www.wikidoc.org/index.php/ADHD_predominantly_inattentive
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wikidoc
AHA, ASA guidelines for stroke
AHA, ASA guidelines for stroke # 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association ## DIAGNOSTIC EVALUATION FOR SECONDARY STROKE PREVENTION ## NUTRITION ## PHYSICAL ACTIVITY ## SMOKING CESS...
AHA, ASA guidelines for stroke Template:AHA, ASA stroke guidelines Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Tarek Nafee, M.D. [2] # 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Associa...
https://www.wikidoc.org/index.php/AHA,_ASA_guidelines_for_stroke
e871fd25d2e825eb92274b7d6d2365cc2d353a41
wikidoc
Activated protein C resistance
Activated protein C resistance Synonyms and Keywords: APC Resistance; # Overview Activated protein C (APC) resistance occurs when APC fails to inactivate downstream coagulation factors, specifically Factor V and Factor VIII. This hemostatic disorder may be caused by either acquired, inherited, or a combination of both...
Activated protein C resistance Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2];Associate Editor(s)-in-Chief: Mohsen Basiri M.D. Synonyms and Keywords: APC Resistance; # Overview Activated protein C (APC) resistance occurs when APC fails to inactivate downstream coagulation factors, specifically Fa...
https://www.wikidoc.org/index.php/APC_resistance
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wikidoc
Abacavir (Patient Information)
Abacavir (Patient Information) # IMPORTANT WARNING Abacavir may cause severe allergic reactions that can lead to death. Stop taking abacavir and call your doctor immediately if you develop a rash or at least one symptom from two of the following groups: - fever - excessive tiredness - upset stomach, vomiting, diarrhea...
Abacavir (Patient Information) Template:Drug header Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # IMPORTANT WARNING Abacavir may cause severe allergic reactions that can lead to death. Stop taking abacavir and call your doctor immediately if you develop a rash or at least one symptom from two of the following ...
https://www.wikidoc.org/index.php/Abacavir_(Patient_Information)
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wikidoc
Abacavir clinical pharmacology
Abacavir clinical pharmacology # Clinical Pharmacology ## Mechanism of Action Abacavir is an antiviral agent . ## Pharmacokinetics The pharmacokinetic properties of abacavir have been studied in asymptomatic, HIV-1-infected adult subjects after administration of a single intravenous (IV) dose of 150 mg and after sin...
Abacavir clinical pharmacology Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Clinical Pharmacology ## Mechanism of Action Abacavir is an antiviral agent [See Clinical Pharmacology (12.4)]. ## Pharmacokinetics The pharmacokinetic properties of abacavir have been studied in asymptomatic, HIV-1-infected adult s...
https://www.wikidoc.org/index.php/Abacavir_clinical_pharmacology
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wikidoc
Abacavir indications and usage
Abacavir indications and usage # Indications and Usage - ZIAGEN Tablets and Oral Solution, in combination with other antiretroviral agents, are indicated for the treatment of human immunodeficiency virus (HIV-1) infection. - Additional important information on the use of ZIAGEN for treatment of HIV-1 infection: - ZIAG...
Abacavir indications and usage Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2] # Indications and Usage - ZIAGEN Tablets and Oral Solution, in combination with other antiretroviral agents, are indicated for the treatment of human immunodeficiency virus (HIV-1) i...
https://www.wikidoc.org/index.php/Abacavir_indications_and_usage
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wikidoc
Abacavir lamivudine zidovudine
Abacavir lamivudine zidovudine # Overview # Category Antiretroviral # US Brand Names TRIZIVIR® # FDA Package Insert Description # Mechanism of Action Abacavir: Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP)...
Abacavir lamivudine zidovudine Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2] # Overview # Category Antiretroviral # US Brand Names TRIZIVIR® # FDA Package Insert Description # Mechanism of Action Abacavir: Abacavir is a carbocyclic synthetic nucleoside ana...
https://www.wikidoc.org/index.php/Abacavir_lamivudine_zidovudine
b927cf3dbddabe9febdd206a8fbc7d98f677fc3b
wikidoc
DNA repair-deficiency disorder
DNA repair-deficiency disorder # Overview An DNA repair-deficiency disorder is a medical condition due to reduced functionality of DNA repair. It is sometimes considered synonymous with the term accelerated aging disease, which is a genetic disorder in which various tissues, organs or systems of the human body age pre...
DNA repair-deficiency disorder Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview An DNA repair-deficiency disorder is a medical condition due to reduced functionality of DNA repair. It is sometimes considered synonymous with the term accelerated aging disease, which is a genetic disorder in which various ...
https://www.wikidoc.org/index.php/Accelerated_aging_disease
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wikidoc
Acebutol (patient information)
Acebutol (patient information) # Why is this medication prescribed? Acebutolol is used to treat high blood pressure.Acebutolol also is used to treat an irregular heartbeat. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. This medication is sometimes prescrib...
Acebutol (patient information) Template:Drug header # Why is this medication prescribed? Acebutolol is used to treat high blood pressure.Acebutolol also is used to treat an irregular heartbeat. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. This medication...
https://www.wikidoc.org/index.php/Acebutol_(patient_information)
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wikidoc
Acetyl-CoA C-acetyltransferase
Acetyl-CoA C-acetyltransferase In enzymology, an acetyl-CoA C-acetyltransferase (EC 2.3.1.9) is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, acetyl-CoA, and two products, CoA and acetoacetyl-CoA. Acetyl-CoA C-acetyltransferase belongs to the thiolase family of enzymes. This enzym...
Acetyl-CoA C-acetyltransferase In enzymology, an acetyl-CoA C-acetyltransferase (EC 2.3.1.9) is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, acetyl-CoA, and two products, CoA and acetoacetyl-CoA. Acetyl-CoA C-acetyltransferase belongs to the thiolase family of enzymes. This enzy...
https://www.wikidoc.org/index.php/Acetyl-CoA_C-acetyltransferase