id stringlengths 40 40 | source stringclasses 9
values | title stringlengths 2 345 | clean_text stringlengths 35 1.63M | raw_text stringlengths 4 1.63M | url stringlengths 4 498 | overview stringlengths 0 10k |
|---|---|---|---|---|---|---|
5b3e3f3fea9b7a60fb8b559b8333e099b83d079d | wikidoc | Cloxacillin Sodium indications and usage | Cloxacillin Sodium indications and usage
# Indications and Usage
The penicillinase-resistant penicillins are indicated in the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drugs. Cultures and susceptibility tests should be performed initially to d... | Cloxacillin Sodium indications and usage
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
# Indications and Usage
The penicillinase-resistant penicillins are indicated in the treatment of infections caused by penicillinase-producing staphylococci which have... | https://www.wikidoc.org/index.php/Cloxacillin_Sodium_indications_and_usage | |
f94cfae026172a8268c60c9e178751692346e7a8 | wikidoc | Cocaine withdrawal (patient information) | Cocaine withdrawal (patient information)
# Overview
Cocaine withdrawal occurs when a heavy cocaine user cuts down or quits taking the drug.
# What are the symptoms of Cocaine withdrawal?
- Primary symptoms may include:
- Agitation and restless behavior
- Depressed mood
- Fatigue
- Generalized malaise
- Vivid and unpl... | Cocaine withdrawal (patient information)
Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Associate Editor-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S.
# Overview
Cocaine withdrawal occurs when a heavy cocaine user cuts down or quits taking the drug.
# What are the symptoms of Cocaine withdrawal?
... | https://www.wikidoc.org/index.php/Cocaine_withdrawal | |
2b7faeee5cdfb9f19c6f3779a936cade2a67e892 | wikidoc | Colposcopic biopsy (patient information) | Colposcopic biopsy (patient information)
For the WikiDoc page for this topic, click here
# Overview
A colposcopy is a special way of looking at the cervix. It uses a light and a low-powered microscope to make the cervix appear much larger. This helps your health care provider find and then biopsy abnormal areas in you... | Colposcopic biopsy (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S.
# Overview
A colposcopy is a special way of looking at the cervix. It uses a light and a low-powered microscope to make the c... | https://www.wikidoc.org/index.php/Colposcopic_biopsy_(patient_information) | |
9b38fa369a9bcc94412db4ffd50a4fecea62b1fd | wikidoc | Congenital diaphragmatic hernia | Congenital diaphragmatic hernia overview
# Overview
Congenital diaphragmatic hernia (CDH) is a term applied to a variety of congenital birth defects that involve abnormal development of the diaphragm. The term is used most commonly in reference to Bochdalek hernia, however it can also apply to Morgagni's hernia, diap... | Congenital diaphragmatic hernia overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz, M.B.B.S
# Overview
Congenital diaphragmatic hernia (CDH) is a term applied to a variety of congenital birth defects that involve abnormal development of the diaphragm. The term is use... | https://www.wikidoc.org/index.php/Congenital_diaphragmatic_hernia_overview | |
8b5863e21d3c3c3fdd39bec3510633374417ebd4 | wikidoc | Contact dermatitis (patient information) | Contact dermatitis (patient information)
For the WikiDoc page for this topic, click here
# Overview
Contact dermatitis is an inflammation of the skin caused by direct contact with an irritating substance.
# What are the symptoms of Contact dermatitis?
- Itching (pruritus) of the skin in exposed areas
- Skin redness o... | Contact dermatitis (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Contact dermatitis is an inflammation of the skin caused by direct contact with an irritating substance.
# What are the symptoms of Contact dermatitis?
- Itching (pru... | https://www.wikidoc.org/index.php/Contact_dermatitis_(patient_information) | |
dc011ad5adc888476834d7f8f6075b5c8f716245 | wikidoc | Coronary vasospasm (patient information) | Coronary vasospasm (patient information)
For the WikiDoc page for this topic, click here
# Overview
Coronary vasospasm is a temporary, sudden narrowing of one of the coronary arteries (the arteries that supply blood to the heart). The spasm slows or stops blood flow through the artery and starves part of the heart of ... | Coronary vasospasm (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S.
# Overview
Coronary vasospasm is a temporary, sudden narrowing of one of the coronary arteries (the arteries that sup... | https://www.wikidoc.org/index.php/Coronary_vasospasm_(patient_information) | |
1eaf3c5d4dcabc4ee165f43285f99ab582441f4b | wikidoc | Cutaneous innervation of the upper limbs | Cutaneous innervation of the upper limbs
Cutaneous innervation refers to the area of the skin which is supplied by a specific nerve.
Modern texts are in agreement about which areas of the skin are served by which nerves, but there are minor variations in some of the details. The borders designated by the diagrams in th... | Cutaneous innervation of the upper limbs
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Cutaneous innervation refers to the area of the skin which is supplied by a specific nerve.
Modern texts are in agreement about which areas of the skin are served by which nerves, but there are minor variations in some of the d... | https://www.wikidoc.org/index.php/Cutaneous_innervation_of_the_upper_limbs | |
a8eb03dfbc90db2acb5dfc0a501f9efec3fc394d | wikidoc | Defects in intrinsic and innate immunity | Defects in intrinsic and innate immunity
# Overview
Defects in intrinsic and innate immunity can result in infection by bacteria, viruses, and fungi.
# Classification
## Bacterial and Parasitic infections
## MSMD and Viral Infections
# IRAK4 Deficiency
- IRAK4 (interleukin 1 receptor associated kinase 4) gene loca... | Defects in intrinsic and innate immunity
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[3], Anmol Pitliya, M.B.B.S. M.D.[4]
# Overview
Defects in intrinsic and innate immunity can result in infection by bacteria, viruses, and fungi.
# Classif... | https://www.wikidoc.org/index.php/Defects_in_intrinsic_and_innate_immunity | |
ff90d426f44d0482214612925129640e113ea5d4 | wikidoc | Dehydroemetine dosage and administration | Dehydroemetine dosage and administration
# Dosage and Administration
Injections should always be given intramuscularly. Intravenous injection is unacceptably dangerous and holds no advantage. At least 6 weeks should elapse before a second course is administered.
In amebic dysentery, supplementary treatment with tetrac... | Dehydroemetine dosage and administration
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Dosage and Administration
Injections should always be given intramuscularly. Intravenous injection is unacceptably dangerous and holds no advantage. At least 6 weeks should elapse before a second course is administered.
In a... | https://www.wikidoc.org/index.php/Dehydroemetine_dosage_and_administration | |
90838bb0d00284f18d9f4ff84cb84b7ecef7b7b7 | wikidoc | Demeclocycline hydrochloride description | Demeclocycline hydrochloride description
# Description
Demeclocycline hydrochloride is an antibiotic isolated from a mutant strain of Streptomyces aureofaciens. Chemically it is 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12, 12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride. ... | Demeclocycline hydrochloride description
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
# Description
Demeclocycline hydrochloride is an antibiotic isolated from a mutant strain of Streptomyces aureofaciens. Chemically it is 7-Chloro-4-(dimethylamino)-1,4... | https://www.wikidoc.org/index.php/Demeclocycline_hydrochloride_description | |
72a62d3c4e55d867b7bf6f274fc570a96eb423b3 | wikidoc | Dexamethasone Oral (patient information) | Dexamethasone Oral (patient information)
# Why this medication is prescribed
Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain... | Dexamethasone Oral (patient information)
Template:Drug header
# Why this medication is prescribed
Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, h... | https://www.wikidoc.org/index.php/Dexamethasone_Oral | |
41b79bb68731376d013c16747f3f81bcc17302de | wikidoc | Diabetes control and complications trial | Diabetes control and complications trial
The Diabetes Control and Complications Trial, or DCCT, was the largest, most comprehensive diabetes study ever conducted at the time.
The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducted this clinical study of 1,441 volunteers with type 1 d... | Diabetes control and complications trial
The Diabetes Control and Complications Trial, or DCCT, was the largest, most comprehensive diabetes study ever conducted at the time.
The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducted this clinical study of 1,441 volunteers with type 1 ... | https://www.wikidoc.org/index.php/Diabetes_control_and_complications_trial | |
34245349e815fc939f8d40e4fc71d4308d41479d | wikidoc | Diabetes mellitus cardiovascular disease | Diabetes mellitus cardiovascular disease
# Overview
Cardiovascular complications of diabetes include both microvascular disease, such as retinopathy, neuropathy, and nephropathy and macrovascular disease such as coronary artery disease and stroke.
# Cardiovascular Disease
Chronic elevation of blood glucose level lead... | Diabetes mellitus cardiovascular disease
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]
# Overview
Cardiovascular complications of diabetes include both microvascular disease, such as retinopathy, neuropathy, and nephropa... | https://www.wikidoc.org/index.php/Diabetes_mellitus_cardiovascular_disease | |
f639e377cc668fad7e64f5df1162885ebe3db5b1 | wikidoc | Diffuse idiopathic skeletal hyperostosis | Diffuse idiopathic skeletal hyperostosis
# Overview
Diffuse idiopathic skeletal hyperostosis is a common condition characterized by bone proliferation at sites of tendinous and ligamentous insertion. The cervical and thoracic spine in particular are affected. There is an association with hyperglycemia and approximatel... | Diffuse idiopathic skeletal hyperostosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Diffuse idiopathic skeletal hyperostosis is a common condition characterized by bone proliferation at sites of tendinous and ligamentous insertion. The cervical and thoracic spine in particular are affected. There i... | https://www.wikidoc.org/index.php/Diffuse_idiopathic_skeletal_hyperostosis | |
2a05772e090ebc9a04147457aa587cf2909ddd88 | wikidoc | Divalproex sodium nonclinical toxicology | Divalproex sodium nonclinical toxicology
# Nonclinical Toxicology
### 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility
Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a mg/m2 basis) for two years. The primary findings we... | Divalproex sodium nonclinical toxicology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Nonclinical Toxicology
### 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertility
Valproate was administered orally to rats and mice at doses of 80 and 170 mg/kg/day (less than the maximum recommended human dose on a... | https://www.wikidoc.org/index.php/Divalproex_sodium_nonclinical_toxicology | |
4c47a5ccf066b9eef9e86e80f44e63c249fa2eb7 | wikidoc | Dutasteride and Tamsulosin hydrochloride | Dutasteride and Tamsulosin hydrochloride
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The edu... | Dutasteride and Tamsulosin hydrochloride
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Deepika Beereddy, MBBS [2]
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare pro... | https://www.wikidoc.org/index.php/Dutasteride_and_Tamsulosin_hydrochloride | |
b1ac0c3d380714bfeb1b8b8265fab46c47593404 | wikidoc | Metoprolol succinate/Hydrochlorothiazide | Metoprolol succinate/Hydrochlorothiazide
Synonyms / Brand Names:
# Disclaimer
WikiDoc Drug Project is a constellation of drug information for healthcare providers and patients vigorously vetted on the basis of FDA package insert, MedlinePlus, Practice Guidelines, Scientific Statements, and scholarly medical literature... | Metoprolol succinate/Hydrochlorothiazide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms / Brand Names:
# Disclaimer
WikiDoc Drug Project is a constellation of drug information for healthcare providers and patients vigorously vetted on the basis of FDA package insert, MedlinePlus, Practice Guidelines, Sci... | https://www.wikidoc.org/index.php/Dutoprol | |
f3f4740a2067383442b72daee8c965f75eee0921 | wikidoc | Ebstein's anomaly of the tricuspid valve | Ebstein's anomaly of the tricuspid valve
# Overview
# Anatomy
# Historical Perspective
# Pathophysiology
# Causes
# Differentiating Ebstein’s anomaly of the tricuspid valve from other Disorders
# Epidemiology and demographics
# Risk Factors
# Natural history, Complications, and Prognosis
# Diagnosis
History a... | Ebstein's anomaly of the tricuspid valve
For patient information, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]}; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]
# Overview
# Anatomy
# Historical Perspectiv... | https://www.wikidoc.org/index.php/Ebstein%27s_Anomaly_of_the_Tricuspid_Valve | |
d4ced06d51d43c4417a6a3abf6d1c360c82d8ce5 | wikidoc | Econazole patient counseling information | Econazole patient counseling information
# PATIENT COUNSELING INFORMATION
See FDA-approved patient labeling (Patient Information)
The patient should be instructed as follows:
Inform patients that Ecoza (econazole nitrate) topical foam, 1% is for topical use only. Ecoza (econazole nitrate) topical foam, 1% is not inten... | Econazole patient counseling information
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
# PATIENT COUNSELING INFORMATION
See FDA-approved patient labeling (Patient Information)
The patient should be instructed as follows:
Inform patients that Ecoza (econ... | https://www.wikidoc.org/index.php/Econazole_patient_counseling_information | |
48961ec42fad2fdde4a07d3df6ee8389fa807aad | wikidoc | Pulmonary empyema historical perspective | Pulmonary empyema historical perspective
# Overview
Pleural infection was first described by Hippocrates as far back as 460-370 B.C.
During this time open chest drainage was the sole treatment modality and was associated with high mortality. In 1873, Playfair gave the first description of a water-seal chest drainage s... | Pulmonary empyema historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]
# Overview
Pleural infection was first described by Hippocrates as far back as 460-370 B.C.[1]
During this time open chest drainage was the sole treatment modalit... | https://www.wikidoc.org/index.php/Empyema_historical_perspective | |
fd7ce0ad242d89f7f08e211dccba7ee49bd96c68 | wikidoc | Endometrial biopsy (patient information) | Endometrial biopsy (patient information)
For the WikiDoc page for this topic, click here
# Overview
Endometrial biopsy is a procedure in which a tissue sample is taken from the lining of the uterus (endometrium), and is checked under a microscope for any abnormal cells or signs of cancer.
# How is the Endometrial bio... | Endometrial biopsy (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S.
# Overview
Endometrial biopsy is a procedure in which a tissue sample is taken from the lining of the uterus (endometrium), a... | https://www.wikidoc.org/index.php/Endometrial_biopsy_(patient_information) | |
09318f3a01cf66acccee9543f369959435963883 | wikidoc | Endosperm expression gene transcriptions | Endosperm expression gene transcriptions
# Human genes
# Gene expressions
# Consensus sequences
Endosperm expression (TGTGTCA).
# Hypotheses
- A1BG has no Endosperm expression in either promoter.
- A1BG is not transcribed by Endosperm expression.
- Endosperm expression does not participate in the transcription of A... | Endosperm expression gene transcriptions
Associate Editor(s)-in-Chief: Henry A. Hoff
# Human genes
# Gene expressions
# Consensus sequences
Endosperm expression (TGTGTCA).[1]
# Hypotheses
- A1BG has no Endosperm expression in either promoter.
- A1BG is not transcribed by Endosperm expression.
- Endosperm expressi... | https://www.wikidoc.org/index.php/Endosperm_expression_gene_transcriptions | |
678ddeb0ea260555919b418d0c027f63032a3383 | wikidoc | Ergoloid Mesylates (patient information) | Ergoloid Mesylates (patient information)
# Why this medication is prescribed
This medication, a combination of several drugs that belong to a group of drugs called ergoloid mesylates, is used to relieve the signs and symptoms of decreased mental capacity due to the aging process.
This medication is sometimes prescribe... | Ergoloid Mesylates (patient information)
Template:Drug header
# Why this medication is prescribed
This medication, a combination of several drugs that belong to a group of drugs called ergoloid mesylates, is used to relieve the signs and symptoms of decreased mental capacity due to the aging process.
This medication ... | https://www.wikidoc.org/index.php/Ergoloid_Mesylates | |
83cd9fa0caa78ddea8afaad2c772fe622478872b | wikidoc | Esophageal atresia (patient information) | Esophageal atresia (patient information)
For the WikiDoc page for this topic, click here
# Overview
Esophageal atresia is a disorder of the digestive system in which the esophagus does not develop properly. The esophagus is the tube that normally carries food from the mouth to the stomach.
# What are the symptoms of ... | Esophageal atresia (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Esophageal atresia is a disorder of the digestive system in which the esophagus does not develop properly. The esophagus is the tube that normally carries food from th... | https://www.wikidoc.org/index.php/Esophageal_atresia_(patient_information) | |
efe716b252862547e2caf514bc0d673121e74532 | wikidoc | Estrogen Injection (patient information) | Estrogen Injection (patient information)
# IMPORTANT WARNING
Estrogen increases the risk that you will develop endometrial cancer (cancer of the lining of the uterus ). The longer you use estrogen, the greater the risk that you will develop endometrial cancer. If you have not had a hysterectomy (surgery to remove the ... | Estrogen Injection (patient information)
Template:Drug header
# IMPORTANT WARNING
Estrogen increases the risk that you will develop endometrial cancer (cancer of the lining of the uterus [womb]). The longer you use estrogen, the greater the risk that you will develop endometrial cancer. If you have not had a hysterec... | https://www.wikidoc.org/index.php/Estrogen_Injection | |
1f3f4b746fd6acdec6ebb9bac697e4526efc17f7 | wikidoc | Farnesyl-diphosphate farnesyltransferase | Farnesyl-diphosphate farnesyltransferase
Squalene synthase (SQS) or farnesyl-diphosphate:farnesyl-diphosphate farnesyl transferase is an enzyme localized to the membrane of the endoplasmic reticulum. SQS participates in the isoprenoid biosynthetic pathway, catalyzing a two-step reaction in which two identical molecule... | Farnesyl-diphosphate farnesyltransferase
Squalene synthase (SQS) or farnesyl-diphosphate:farnesyl-diphosphate farnesyl transferase is an enzyme localized to the membrane of the endoplasmic reticulum. SQS participates in the isoprenoid biosynthetic pathway, catalyzing a two-step reaction in which two identical molecul... | https://www.wikidoc.org/index.php/Farnesyl-diphosphate_farnesyltransferase | |
42f7b76d138cf3e21d0d2fda21cdd1da13ddd6dc | wikidoc | Gastroesophageal reflux disease | Gastroesophageal reflux disease overview
# Overview
Gastroesophageal reflux disease is defined as chronic symptoms due to damage to the esophageal mucosa as a result of abnormal reflux of acidic stomach contents into the esophagus. This is commonly due to transient or permanent changes in the barrier between the eso... | Gastroesophageal reflux disease overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
# Overview
Gastroesophageal reflux disease is defined as chronic symptoms due to damage to the esophageal mucosa as a result of abnormal reflux of acidic stomach conten... | https://www.wikidoc.org/index.php/Gastroesophageal_reflux_disease_overview | |
206960d7b5cc8b62dfbda1d3124fc9978be6fe26 | wikidoc | Georgetown University School of Medicine | Georgetown University School of Medicine
Georgetown University School of Medicine (GUSOM) is Georgetown University's medical school, and part of the Georgetown University Medical Center. It is located on the University's main campus in Washington, DC. Opened in 1851, Georgetown's School of Medicine provides a compreh... | Georgetown University School of Medicine
Template:Infobox University
Georgetown University School of Medicine (GUSOM) is Georgetown University's medical school, and part of the Georgetown University Medical Center. It is located on the University's main campus in Washington, DC. Opened in 1851, Georgetown's School o... | https://www.wikidoc.org/index.php/Georgetown_University_School_of_Medicine | |
c391d7a2a05946684a1ac375a1b12fc4dd39aa7a | wikidoc | Glomerular disease (patient information) | Glomerular disease (patient information)
For the WikiDoc page for this topic, click here
# Overview
Glomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged.
# What are the symptoms of Glomerulonephritis?
Common symptoms of glomerulo... | Glomerular disease (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
# Overview
Glomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filte... | https://www.wikidoc.org/index.php/Glomerular_disease_(patient_information) | |
2f75cf5f909652c39decc563b1abd588691c9298 | wikidoc | Gluten-sensitive idiopathic neuropathies | Gluten-sensitive idiopathic neuropathies
Diagnosis of gluten-sensitive neuropathies without a clear cause is on the rise. These idiopathic neuropathies were first identified by anti-gliadin IgG (AGA) screening of patients. The criteria has been critiqued because of the large misdiagnosis rate of coeliac disease (CD), a... | Gluten-sensitive idiopathic neuropathies
Template:Gluten sensitivity
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Diagnosis of gluten-sensitive neuropathies without a clear cause is on the rise. These idiopathic neuropathies were first identified by anti-gliadin IgG (AGA) screening of patients.[1] The criteria h... | https://www.wikidoc.org/index.php/Gluten-sensitive_idiopathic_neuropathies | |
1144e0e22694c9d259363e6966e90a11aac963fe | wikidoc | Glyceraldehyde 3-phosphate dehydrogenase | Glyceraldehyde 3-phosphate dehydrogenase
Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) (EC 1.2.1.12) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established ... | Glyceraldehyde 3-phosphate dehydrogenase
Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) (EC 1.2.1.12) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. In addition to this long established... | https://www.wikidoc.org/index.php/Glyceraldehyde-3-phosphate_dehydrogenase | |
b82a7681c5a5c6282a247b44123bfd8fffe0bc9c | wikidoc | Glycogen storage disease type I | Glycogen storage disease type I overview
# Overview
Glycogen storage disease type 1 also known as Von Gierke's disease is an enzymopathy. The most common defect is deficiency of glucose-6-phosphatase enzyme. Glucose-6-phosphatase is an enzyme located on the inner membrane of the endoplasmic reticulum. Glucose-6-phosph... | Glycogen storage disease type I overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
# Overview
Glycogen storage disease type 1 also known as Von Gierke's disease is an enzymopathy. The most common defect is deficiency of glucose-6-phosphatase en... | https://www.wikidoc.org/index.php/Glycogen_storage_disease_type_I_overview | |
4b0bfbaa3c91dfb9b5ae29d1f19656406b4cb97a | wikidoc | Glycoprotein 2-beta-D-xylosyltransferase | Glycoprotein 2-beta-D-xylosyltransferase
# Overview
In enzymology, a glycoprotein 2-beta-D-xylosyltransferase (EC 2.4.2.38) is an enzyme that catalyzes the chemical reaction
The 5 substrates of this enzyme are UDP-D-xylose, ], -beta-D-]], ], and ], whereas its 5 products are UDP, ], -], -beta-D-mannosyl-(1->4)-N-acety... | Glycoprotein 2-beta-D-xylosyltransferase
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
In enzymology, a glycoprotein 2-beta-D-xylosyltransferase (EC 2.4.2.38) is an enzyme that catalyzes the chemical reaction
The 5 substrates of this enzyme are UDP-D-xylose, [[N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-a... | https://www.wikidoc.org/index.php/Glycoprotein_2-beta-D-xylosyltransferase | |
d1783a0ebbc1e015f9214ea9000c2be928f50fa4 | wikidoc | Granulosa cell tumour primary prevention | Granulosa cell tumour primary prevention
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
# Overview
# Primary Prevention
- There are no standard recommendations for screening for ovarian cancer.
- BRCA testing may be done in women at high risk for ovarian cancer.
- R... | Granulosa cell tumour primary prevention
Template:Granulosa cell tumour
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
# Primary Prevention
- There are no standard recommendations for screening for ovari... | https://www.wikidoc.org/index.php/Granulosa_cell_tumour_primary_prevention | |
564a8b5a93155d5cc58916d940f24623c6e1315a | wikidoc | Group B streptococcal infection | Group B streptococcal infection overview
# Overview
Despite substantial progress in prevention of perinatal Group B Streptococal (GBS) disease since the 1990s, GBS remains the leading cause of early-onset neonatal sepsis in the United States. Universal screening at 35--37 weeks' gestation for maternal GBS colonizatio... | Group B streptococcal infection overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [5]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [6]
# Overview
Despite substantial progress in prevention of perinatal Group B Streptococal (GBS) disease since the 1990s, GBS remains the leading cause of early-onset neonatal ... | https://www.wikidoc.org/index.php/Group_B_streptococcal_infection_overview | |
905b5c925d9b8de13527d0767ff9fdce2d517a4d | wikidoc | HFrEF exacerbation (Assessment and Plan) | HFrEF exacerbation (Assessment and Plan)
Author: William J Gibson MD, PhD
History of HFrEF (last TTE XX;LVEF XX%) secondary to XX . Current exacerbation most likely precipitated by . Possible other etiologies (although less likely): ischemia/infarction(15%), HTN, renal failure -> inc. preload, drugs/toxins (eg etoh), ... | HFrEF exacerbation (Assessment and Plan)
Author: William J Gibson MD, PhD
History of HFrEF (last TTE XX;LVEF XX%) secondary to XX [ischemia,non-ischemic dilated cardiomyopathy, non-ischemic restrictive cardiomyopathy] . Current exacerbation most likely precipitated by [medication/dietary non-compliance(40%)]. Possible... | https://www.wikidoc.org/index.php/HFrEF_exacerbation_(Assessment_and_Plan) | |
1420b0f5ef859077e3b643733f3ced914615f68a | wikidoc | HLH (Hemophagocytic lymphohistiocytosis) | HLH (Hemophagocytic lymphohistiocytosis)
Hemophagocytic lymphohistiocytosis (HLH) is an unusual syndrome characterized by fever, splenomegaly, jaundice, and the pathologic finding of hemophagocytosis. This is phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and oth... | HLH (Hemophagocytic lymphohistiocytosis)
Hemophagocytic lymphohistiocytosis (HLH) is an unusual syndrome characterized by fever, splenomegaly, jaundice, and the pathologic finding of hemophagocytosis. This is phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and ot... | https://www.wikidoc.org/index.php/HLH_(Hemophagocytic_lymphohistiocytosis) | |
7d923d7cc3927fc89f3d28e772208a4bc338cb59 | wikidoc | Hearing loss with craniofacial syndromes | Hearing loss with craniofacial syndromes
Hearing loss with craniofacial syndromes is a common occurrence. Many of these multianomaly disorders involve structural malformations of the outer or middle ear, making a significant hearing loss highly likely.
# Treacher Collins syndrome
Individuals with Treacher Collins synd... | Hearing loss with craniofacial syndromes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Hearing loss with craniofacial syndromes is a common occurrence. Many of these multianomaly disorders involve structural malformations of the outer or middle ear, making a significant hearing loss highly likely.
# Treacher Col... | https://www.wikidoc.org/index.php/Hearing_loss_with_craniofacial_syndromes | |
baa8702e45d9f5c90b0f37041df35c0f63c7a165 | wikidoc | High-velocity galaxy radiation astronomy | High-velocity galaxy radiation astronomy
"The irregular galaxy NGC 1427A is a spectacular example of the resulting stellar rumble. Under the gravitational grasp of a large gang of galaxies, called the Fornax cluster, the small bluish galaxy is plunging headlong into the group at 600 kilometers per second or nearly 400 ... | High-velocity galaxy radiation astronomy
Editor-In-Chief: Henry A. Hoff
"The irregular galaxy NGC 1427A is a spectacular example of the resulting stellar rumble. Under the gravitational grasp of a large gang of galaxies, called the Fornax cluster, the small bluish galaxy is plunging headlong into the group at 600 kilo... | https://www.wikidoc.org/index.php/High-velocity_galaxy_radiation_astronomy | |
9e35035f76627f8fa890a3964ef143d1df17a187 | wikidoc | Hydrocodone bitartrate and acetaminophen | Hydrocodone bitartrate and acetaminophen
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The edu... | Hydrocodone bitartrate and acetaminophen
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider... | https://www.wikidoc.org/index.php/Hydrocodone_bitartrate_and_acetaminophen | |
3b94181382b966abf2ee42ee06dc09d628e84b39 | wikidoc | Hydroxychloroquine (patient information) | Hydroxychloroquine (patient information)
# Why this medication is prescribed
Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms hav... | Hydroxychloroquine (patient information)
Template:Drug header
# Why this medication is prescribed
Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patie... | https://www.wikidoc.org/index.php/Hydroxychloroquine_(patient_information) | |
3e2657a16be1e66a1cf042dcfe9cb44e804e9841 | wikidoc | Hyperlipoproteinemia laboratory findings | Hyperlipoproteinemia laboratory findings
# Overview
Complete fasting lipid profile should be obtained for making the diagnosis of hyperlipidemia and risk stratification for coronary heart diseases. In the absence of symptoms or signs suggestive of a particular disorder, a limited workup should also be performed to rul... | Hyperlipoproteinemia laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hardik Patel, M.D., Aditya Govindavarjhulla, M.B.B.S. [2]
# Overview
Complete fasting lipid profile should be obtained for making the diagnosis of hyperlipidemia and risk stratification for coro... | https://www.wikidoc.org/index.php/Hyperlipoproteinemia_laboratory_findings | |
a74d0be1649dec396518be67e4a86bbe1b1205a9 | wikidoc | Hypogastric pain resident survival guide | Hypogastric pain resident survival guide
# Overview
The hypogastrium (alternative names including hypogastric region, pubic region and suprapubic region) is an area of the human abdomen located below the navel. The pubis bone constitutes its lower limit.
# Causes
- Bladder stone
- Bladder cancer (transitional cell ca... | Hypogastric pain resident survival guide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2]
# Overview
The hypogastrium (alternative names including hypogastric region, pubic region and suprapubic region) is an area of the human abdomen located below the navel. Th... | https://www.wikidoc.org/index.php/Hypogastric_pain_resident_survival_guide | |
0aed825a8d461e1c9d010c68c6a14c907bb94980 | wikidoc | Hypoplastic left heart syndrome | Hypoplastic left heart syndrome overview
# Overview
Hypoplasia can affect the heart, which typically results in the failure of either the right ventricle or the left ventricle to develop adequately, leaving only one side of the heart capable of pumping blood to the body and lungs. Hypoplasia of the heart is rare but ... | Hypoplastic left heart syndrome overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S.[2], Cafer Zorkun, M.D., Ph.D. [3], Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S.[5]
# Overview
Hypoplasia can affect the heart, which typica... | https://www.wikidoc.org/index.php/Hypoplastic_left_heart_syndrome_overview | |
b86e516069efc9b972ce930a0ecb738fa4b3d9ac | wikidoc | IMITREX injection nonclinical toxicology | IMITREX injection nonclinical toxicology
# Nonclinical Toxicology
### Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis: In carcinogenicity studies, rats and mice were given sumatriptan by oral gavage. Mice were dosed for 78 weeks and rats were dosed for 104 weeks. Average exposures achieved in mice... | IMITREX injection nonclinical toxicology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Nonclinical Toxicology
### Carcinogenesis, Mutagenesis, Impairment of Fertility
Carcinogenesis: In carcinogenicity studies, rats and mice were given sumatriptan by oral ga... | https://www.wikidoc.org/index.php/IMITREX_injection_nonclinical_toxicology | |
356259e6e483c84f12c0aa707469d994e1c5316d | wikidoc | IMITREX tablet dosage and administration | IMITREX tablet dosage and administration
# Dosage and Administration
### Dosing Information
The recommended dose of IMITREX Tablets is 25 mg, 50 mg, or 100 mg. Doses of 50 mg and 100 mg may provide a greater effect than the 25-mg dose, but doses of 100 mg may not provide a greater effect than the 50-mg dose. Higher d... | IMITREX tablet dosage and administration
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Dosage and Administration
### Dosing Information
The recommended dose of IMITREX Tablets is 25 mg, 50 mg, or 100 mg. Doses of 50 mg and 100 mg may provide a greater effect... | https://www.wikidoc.org/index.php/IMITREX_tablet_dosage_and_administration | |
c40bac5d298636671280026ece230988e36e6d28 | wikidoc | Inappropriate sinus tachycardia | Inappropriate sinus tachycardia overview
# Overview
Inappropriate sinus tachycardia is an uncommon form of supraventricular tachycardia (SVT).
# Epidemiology and Demographics
The condition was first formally recognized as a veritable syndrome in 1979.
# Pathophysiology
The mechanism of the arrhythmia primarily invo... | Inappropriate sinus tachycardia overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Inappropriate sinus tachycardia is an uncommon form of supraventricular tachycardia (SVT).
# Epidemiology and Demographics
The condition was first formally recognized as a veritable syndrome in 1979.
# Pathophysi... | https://www.wikidoc.org/index.php/Inappropriate_sinus_tachycardia_overview | |
7ae32e6231be1710d0fe68e88cda63ef9be2388c | wikidoc | Inborn errors of carbohydrate metabolism | Inborn errors of carbohydrate metabolism
Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of carbohydrates. An example is lactose intolerance. Carbohydrates account for a major portion of the human diet and are metabolized into three principal monosacchari... | Inborn errors of carbohydrate metabolism
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of carbohydrates. An example is lactose intolerance. Carbohydrates account for a major portion of the human diet a... | https://www.wikidoc.org/index.php/Inborn_errors_of_carbohydrate_metabolism | |
dea961b905473aaed263853e112a452c618a6eb4 | wikidoc | Industrial and organizational psychology | Industrial and organizational psychology
Robert G. Badgett, M.D.
Industrial and organizational psychology is "the branch of applied psychology concerned with the application of psychologic principles and methods to industrial problems including selection and training of workers, working conditions, etc."
Research studi... | Industrial and organizational psychology
Robert G. Badgett, M.D.[1]
Industrial and organizational psychology is "the branch of applied psychology concerned with the application of psychologic principles and methods to industrial problems including selection and training of workers, working conditions, etc."[1]
Researc... | https://www.wikidoc.org/index.php/Industrial_and_organizational_psychology | |
d83e4acd96ea4594eef4516a1b4be6004241cd22 | wikidoc | Interferon alfa-2a clinical pharmacology | Interferon alfa-2a clinical pharmacology
# Clinical Pharmacology
The mechanism by which Interferon alfa-2a, recombinant, or any other interferon, exerts antitumor or antiviral activity is not clearly understood. However, it is believed that direct antiproliferative action against tumor cells, inhibition of virus repli... | Interferon alfa-2a clinical pharmacology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Clinical Pharmacology
The mechanism by which Interferon alfa-2a, recombinant, or any other interferon, exerts antitumor or antiviral activity is not clearly understood. How... | https://www.wikidoc.org/index.php/Interferon_alfa-2a_clinical_pharmacology | |
292e3fad25f139cda9f60e2af28a66b83a3f65bd | wikidoc | Interferon alfa-2b clinical pharmacology | Interferon alfa-2b clinical pharmacology
# Clinical Pharmacology
## General
The interferons are a family of naturally occurring small proteins and glycoproteins with molecular weights of approximately 15,000 to 27,600 daltons produced and secreted by cells in response to viral infections and to synthetic or biologica... | Interferon alfa-2b clinical pharmacology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Clinical Pharmacology
## General
The interferons are a family of naturally occurring small proteins and glycoproteins with molecular weights of approximately 15,000 to 27,... | https://www.wikidoc.org/index.php/Interferon_alfa-2b_clinical_pharmacology | |
5ee5b19460cae8b927ce23ec8958d1617fca9eff | wikidoc | Interferon alfa-2b indications and usage | Interferon alfa-2b indications and usage
# Indications And Usage
## Hairy Cell Leukemia
INTRON® A is indicated for the treatment of patients 18 years of age or older with hairy cell leukemia.
## Malignant Melanoma
INTRON A is indicated as adjuvant to surgical treatment in patients 18 years of age or older with malig... | Interferon alfa-2b indications and usage
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Indications And Usage
## Hairy Cell Leukemia
INTRON® A is indicated for the treatment of patients 18 years of age or older with hairy cell leukemia.
## Malignant Melanoma... | https://www.wikidoc.org/index.php/Interferon_alfa-2b_indications_and_usage | |
6b3af0d5e02b118f4ec26e2998e0b8483f6284ff | wikidoc | Journal of the Royal Statistical Society | Journal of the Royal Statistical Society
The Journal of the Royal Statistical Society is a series of three peer-reviewed statistics journals published by Blackwell Publishing for the London-based Royal Statistical Society.
# History
The Statistical Society of London was founded in 1834, but would not begin producing a... | Journal of the Royal Statistical Society
Template:Infobox Journal
The Journal of the Royal Statistical Society is a series of three peer-reviewed statistics journals published by Blackwell Publishing for the London-based Royal Statistical Society.
# History
Template:Wikisource
The Statistical Society of London was fo... | https://www.wikidoc.org/index.php/Journal_of_the_Royal_Statistical_Society | |
40516273dea604f6120fc04454c8921e25cebdb5 | wikidoc | Kendall tau rank correlation coefficient | Kendall tau rank correlation coefficient
# Overview
The Kendall tau rank correlation coefficient (or simply the Kendall tau coefficient, Kendall's τ or Tau test(s)) is used to measure the degree of correspondence between two rankings and assessing the significance of this correspondence. In other words, it measures th... | Kendall tau rank correlation coefficient
# Overview
The Kendall tau rank correlation coefficient (or simply the Kendall tau coefficient, Kendall's τ or Tau test(s)) is used to measure the degree of correspondence between two rankings and assessing the significance of this correspondence. In other words, it measures th... | https://www.wikidoc.org/index.php/Kendall_tau_rank_correlation_coefficient | |
e821574f24ea1f1328706a8d48096368897e121f | wikidoc | Killer cell immunoglobulin-like receptor | Killer cell immunoglobulin-like receptor
Killer cell immunoglobulin-like receptor is a receptor for natural killer cells.
# Genes
- two domains, long cytoplasmic tail: KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5A, KIR2DL5B,
- two domains, short cytoplasmic tail: KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5
- three doma... | Killer cell immunoglobulin-like receptor
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Killer cell immunoglobulin-like receptor is a receptor for natural killer cells.
# Genes
- two domains, long cytoplasmic tail: KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5A, KIR2DL5B,
- two domains, short cytoplasmic tail: KIR2... | https://www.wikidoc.org/index.php/Killer_cell_immunoglobulin-like_receptor | |
ccf418211182c83d5dd4b0aebba4410645342515 | wikidoc | Leucovorin Calcium (patient information) | Leucovorin Calcium (patient information)
# About your treatment
Your doctor has ordered the drug leucovorin to help treat your illness. The drug is given by injection into a vein or taken by mouth with tablets.
This medication is used:
- to prevent or treat the toxicities of medications known as folic acid antagonists... | Leucovorin Calcium (patient information)
Template:Drug header
# About your treatment
Your doctor has ordered the drug leucovorin to help treat your illness. The drug is given by injection into a vein or taken by mouth with tablets.
This medication is used:
- to prevent or treat the toxicities of medications known as ... | https://www.wikidoc.org/index.php/Leucovorin_Calcium | |
e60ea9c3d49c675e6f6f47c48f6b2e7edef40f5b | wikidoc | Lisinoprmil clinical laboratory findings | Lisinopril clinical laboratory findings
# Serum Electrolytes
Hyperkalemia, hyponatremia.
# Creatinine, Blood Urea Nitrogen
Minor increases in blood urea nitrogen and serum creatinine, reversible upon discontinuation of therapy, were observed in about 2% of patients with essential hypertension treated with lisinopril ... | Lisinopril clinical laboratory findings
# Serum Electrolytes
Hyperkalemia, hyponatremia.
# Creatinine, Blood Urea Nitrogen
Minor increases in blood urea nitrogen and serum creatinine, reversible upon discontinuation of therapy, were observed in about 2% of patients with essential hypertension treated with lisinopril ... | https://www.wikidoc.org/index.php/Lisinopril_clinical_laboratory_findings | |
ff6833773cf8fe4a988bc8ba071c4dd0ec2e971f | wikidoc | Lower gastrointestinal bleeding | Lower gastrointestinal bleeding overview
# Overview
Lower gastrointestinal bleeding is defined as blood loss originating distal to the ligament of Treitz. It accounts for 24% to 33% of all hospital admissions for gastrointestinal bleeding and is responsible for 1% of hospital admissions in the United States. It can pr... | Lower gastrointestinal bleeding overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
# Overview
Lower gastrointestinal bleeding is defined as blood loss originating distal to the ligament of Treitz. It accounts for 24% to 33% of all hospital admissions ... | https://www.wikidoc.org/index.php/Lower_gastrointestinal_bleeding_overview | |
130f21a6a640f68581c1e73224a7fb9f5c8f735b | wikidoc | Lysophosphatidic acid phosphatase type 6 | Lysophosphatidic acid phosphatase type 6
Lysophosphatidic acid phosphatase type 6 is an acid phosphatase enzyme that is encoded in humans by the ACP6 gene.
It acts as a phosphomonoesterase at low pHs. It is responsible for the hydrolysis of Lysophosphatidic acids (LPAs) to their respective monoacylglycerols and the rel... | Lysophosphatidic acid phosphatase type 6
Lysophosphatidic acid phosphatase type 6 is an acid phosphatase enzyme that is encoded in humans by the ACP6 gene.[1][2]
It acts as a phosphomonoesterase at low pHs.[3] It is responsible for the hydrolysis of Lysophosphatidic acids (LPAs) to their respective monoacylglycerols a... | https://www.wikidoc.org/index.php/Lysophosphatidic_acid_phosphatase_type_6 | |
c1733d20d1d8d502b98e12c4ba516afc02e358cc | wikidoc | Megakaryocyte-associated tyrosine kinase | Megakaryocyte-associated tyrosine kinase
Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene.
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 dom... | Megakaryocyte-associated tyrosine kinase
Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene.[1][2][3]
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 a... | https://www.wikidoc.org/index.php/Megakaryocyte-associated_tyrosine_kinase | |
99152eef6229a6de9c3bf343ce82003863ad8a30 | wikidoc | Melanin-concentrating hormone receptor 1 | Melanin-concentrating hormone receptor 1
Melanin-concentrating hormone receptor 1, also known as MCH1, is one of the melanin-concentrating hormone receptors found in all mammals.
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds me... | Melanin-concentrating hormone receptor 1
Melanin-concentrating hormone receptor 1, also known as MCH1, is one of the melanin-concentrating hormone receptors found in all mammals. [1]
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which bind... | https://www.wikidoc.org/index.php/Melanin-concentrating_hormone_receptor_1 | |
c40aa4897b08204dcb6ca760bd876d91a47f132b | wikidoc | Melanin-concentrating hormone receptor 2 | Melanin-concentrating hormone receptor 2
Melanin-concentrating hormone receptor 2 (MCH2) also known as G-protein coupled receptor 145 (GPR145) is a protein that in humans is encoded by the MCHR2 gene.
MCH2 is also found in dogs, ferrets, and some other primates and carnivores, but is not found in mice or rats. This has... | Melanin-concentrating hormone receptor 2
Melanin-concentrating hormone receptor 2 (MCH2) also known as G-protein coupled receptor 145 (GPR145) is a protein that in humans is encoded by the MCHR2 gene.[1][2][3]
MCH2 is also found in dogs, ferrets, and some other primates and carnivores, but is not found in mice or rats... | https://www.wikidoc.org/index.php/Melanin-concentrating_hormone_receptor_2 | |
382d03d0605062c451fc8fb09d64560c220c0fba | wikidoc | Methocarbamol Oral (patient information) | Methocarbamol Oral (patient information)
# Why this medication is prescribed
Methocarbamol, a muscle relaxant, is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.
This medication is sometimes prescribed for othe... | Methocarbamol Oral (patient information)
Template:Drug header
# Why this medication is prescribed
Methocarbamol, a muscle relaxant, is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.
This medication is sometim... | https://www.wikidoc.org/index.php/Methocarbamol_Oral | |
4f7979534dc8d172c06b330a3904ad656f003669 | wikidoc | Methoxy polyethylene glycol-epoetin beta | Methoxy polyethylene glycol-epoetin beta
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The edu... | Methoxy polyethylene glycol-epoetin beta
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vignesh Ponnusamy, M.B.B.S. [2]
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcar... | https://www.wikidoc.org/index.php/Methoxy_polyethylene_glycol-epoetin_beta | |
c40eb563132b54c6b2e0f87a52f9ad68b27a6d9d | wikidoc | Methysergide use in specific populations | Methysergide use in specific populations
# Use In Specific Populations
### Pregnancy Category: X
Sansert® (methysergide maleate) is contraindicated in pregnancy due to its oxytocic actions.
### Nursing Mothers
There are no specific studies on the use of Sansert® (methysergide maleate) in nursing mothers. Ergot alkal... | Methysergide use in specific populations
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Use In Specific Populations
### Pregnancy Category: X
Sansert® (methysergide maleate) is contraindicated in pregnancy due to its oxytocic actions.
### Nursing Mothers
There are no specific studies on the use of Sansert® (m... | https://www.wikidoc.org/index.php/Methysergide_use_in_specific_populations | |
8e5930fcb1a672b7443ae26253bafce9956c1807 | wikidoc | Metipranolol use in specific populations | Metipranolol use in specific populations
# Use in Specific Populations
### Pregnancy
Teratogenic Effects
### Pregnancy Category: C
No drug related effects were reported for the segment II teratology study in fetal rats after administration, during organogenesis, to dams of up to 50 mg/kg/day. Metipranolol ophthalmic... | Metipranolol use in specific populations
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Use in Specific Populations
### Pregnancy
Teratogenic Effects
### Pregnancy Category: C
No drug related effects were reported for the segment II teratology study in fetal rats after administration, during organogenesis, to... | https://www.wikidoc.org/index.php/Metipranolol_use_in_specific_populations | |
78675f2d7480b19a99617fd83ee573afcf5f4ef8 | wikidoc | Metronidazole Oral (patient information) | Metronidazole Oral (patient information)
# IMPORTANT WARNING
Metronidazole can cause cancer in laboratory animals. Talk to your doctor about the risks and benefits of using this medication.
# Why this medication is prescribed
Metronidazole eliminates bacteria and other microorganisms that cause infections of the repr... | Metronidazole Oral (patient information)
Template:Drug header
# IMPORTANT WARNING
Metronidazole can cause cancer in laboratory animals. Talk to your doctor about the risks and benefits of using this medication.
# Why this medication is prescribed
Metronidazole eliminates bacteria and other microorganisms that cause ... | https://www.wikidoc.org/index.php/Metronidazole_Oral | |
990561f0bd35d4b325096f88ebde1b450b72ed88 | wikidoc | Microsomal triglyceride transfer protein | Microsomal triglyceride transfer protein
Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP gene.
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal t... | Microsomal triglyceride transfer protein
Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP gene.[1][2]
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric micro... | https://www.wikidoc.org/index.php/Microsomal_triglyceride_transfer_protein | |
927fb11bf4f52d5c0663463bb6427c8f3c7ead95 | wikidoc | Mitochondrial membrane transport protein | Mitochondrial membrane transport protein
Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to transport molecules and other factors such as ions into or out of the organelles.
# Examples
Examples of mitochondrial transport proteins include the following... | Mitochondrial membrane transport protein
Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to transport molecules and other factors such as ions into or out of the organelles.
# Examples
Examples of mitochondrial transport proteins include the followin... | https://www.wikidoc.org/index.php/Mitochondrial_membrane_transport_protein | |
dbd3ddcbbc7ad5b8709e57a6828b27e23c441a38 | wikidoc | Mixed connective tissue disease | Mixed connective tissue disease overview
# Overview
MCTD was first defined by Gordon C.Sharp et al., in 1972. MCTD is a systemic autoimmune disease that is characterized by overlapping symptoms of two or more systemic autoimmune diseases (SLE, RA, DM, polymyositis, and scleroderma) and the presence of antibodies again... | Mixed connective tissue disease overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
# Overview
MCTD was first defined by Gordon C.Sharp et al., in 1972. MCTD is a systemic autoimmune disease that is characterized by overlapping symptoms of two or more... | https://www.wikidoc.org/index.php/Mixed_connective_tissue_disease_overview | |
2195e88c3350f2547de13bc5d76ee6c8b1c75966 | wikidoc | Muscular dystrophy (patient information) | Muscular dystrophy (patient information)
For the WikiDoc page for this topic, click here
# Overview
Muscular dystrophy is a group of inherited disorders that involve muscle weakness and loss of muscle tissue, which get worse over time.
# What are the symptoms of Muscular dystrophy?
Symptoms vary with the different ty... | Muscular dystrophy (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Muscular dystrophy is a group of inherited disorders that involve muscle weakness and loss of muscle tissue, which get worse over time.
# What are the symptoms of Mus... | https://www.wikidoc.org/index.php/Muscular_dystrophy_(patient_information) | |
16f170946281d8edf8a802a76cc2a211bca4ae72 | wikidoc | Myotonia congenita (patient information) | Myotonia congenita (patient information)
For the WikiDoc page for this topic, click here
# Overview
Myotonia congenita is an inherited condition that affects muscle relaxation. It is congenital, meaning that it is present from birth.
# What are the symptoms of Myotonia congenita?
The hallmark of this condition is the... | Myotonia congenita (patient information)
For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Alexandra M. Palmer
# Overview
Myotonia congenita is an inherited condition that affects muscle relaxation. It is congenital, meaning that it is pr... | https://www.wikidoc.org/index.php/Myotonia_congenita_(patient_information) | |
7e2ff08815b07cf71e0782983e4e6824da00862d | wikidoc | NADH dehydrogenase (ubiquinone), alpha 1 | NADH dehydrogenase (ubiquinone), alpha 1
NADH dehydrogenase 1 alpha subcomplex subunit 1 is a protein that in humans is encoded by the NDUFA1 gene. The NDUFA1 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the el... | NADH dehydrogenase (ubiquinone), alpha 1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 is a protein that in humans is encoded by the NDUFA1 gene.[1][2] The NDUFA1 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five ... | https://www.wikidoc.org/index.php/NADH_dehydrogenase_(ubiquinone),_alpha_1 | |
1e95a2c5e147ae89ae47b47ca2f70cc69961624a | wikidoc | National Human Genome Research Institute | National Human Genome Research Institute
The National Human Genome Research Institute (NHGRI) is a division of the National Institutes of Health, located in Bethesda, Maryland.
NHGRI began as the National Center for Human Genome Research (NCHGR), which was established in 1989 to carry out the role of the NIH in the Int... | National Human Genome Research Institute
Template:Wikify
The National Human Genome Research Institute (NHGRI) is a division of the National Institutes of Health, located in Bethesda, Maryland.
NHGRI began as the National Center for Human Genome Research (NCHGR), which was established in 1989 to carry out the role of t... | https://www.wikidoc.org/index.php/NHGRI | |
265e6630929b30bda6becb8cc2bdf13c64966e71 | wikidoc | National Board of Chiropractic Examiners | National Board of Chiropractic Examiners
The National Board of Chiropractic Examiners (NBCE) is a non-profit national and international testing organization for the chiropractic profession that develops, administers, analyzes, scores, and reports results from various examinations. Examinations are offered twice a year ... | National Board of Chiropractic Examiners
The National Board of Chiropractic Examiners (NBCE) is a non-profit national and international testing organization for the chiropractic profession that develops, administers, analyzes, scores, and reports results from various examinations. Examinations are offered twice a year... | https://www.wikidoc.org/index.php/National_Board_of_Chiropractic_Examiners | |
eb0bea388a56a5e43f253a464a4f954c314f75c3 | wikidoc | National Tobacco Cessation Collaborative | National Tobacco Cessation Collaborative
# Background
The National Tobacco Cessation Collaborative (NTCC) was formed in June 2005 to improve the public's health by increasing successful cessation among tobacco users in the U.S. and Canada through collaborative efforts of committed organizations. Collaborative members ... | National Tobacco Cessation Collaborative
# Background
The National Tobacco Cessation Collaborative (NTCC) was formed in June 2005 to improve the public's health by increasing successful cessation among tobacco users in the U.S. and Canada through collaborative efforts of committed organizations. Collaborative members ... | https://www.wikidoc.org/index.php/National_Tobacco_Cessation_Collaborative | |
e23f9efe6437ef3dc32fb594ce1fa35e864c8160 | wikidoc | Neanderthal interaction with Cro-Magnons | Neanderthal interaction with Cro-Magnons
Around 45,000 years ago, the Neanderthals began to be displaced by, or assimilated with, modern humans (Homo sapiens), as the Cro-Magnon people appeared in Europe. Despite this, regional pockets of Neanderthals held on for thousands of years in such areas as modern-day Croatia a... | Neanderthal interaction with Cro-Magnons
Around 45,000 years ago, the Neanderthals began to be displaced by, or assimilated with, modern humans (Homo sapiens), as the Cro-Magnon people appeared in Europe.[citation needed] Despite this, regional pockets of Neanderthals held on for thousands of years in such areas as mo... | https://www.wikidoc.org/index.php/Neanderthal_interaction_with_Cro-Magnons | |
2a93e2b2e0f9b242d319a62ec16f789ee531b924 | wikidoc | Pediatric sepsis resident survival guide | Pediatric sepsis resident survival guide
# Diagnostic Criteria
## Systemic Inflammatory Response Syndrome
Systemic inflammatory response syndrome (SIRS) represents the complex findings resulting from systemic activation of the innate immune response triggered by localized or generalized infection, trauma, thermal inj... | Pediatric sepsis resident survival guide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Diagnostic Criteria
## Systemic Inflammatory Response Syndrome
Systemic inflammatory response syndrome (SIRS) represents the complex findings resulting from systemic activation of the innate immune response triggered by loc... | https://www.wikidoc.org/index.php/Neonatal_sepsis_resident_survival_guide | |
1e5f178edcf9a328a9e94b7ea2cc27ca8587aa79 | wikidoc | Nephritic syndrome (patient information) | Nephritic syndrome (patient information)
For the WikiDoc page for this topic, click here
# Overview
Acute nephritic syndrome is a group of disorders that cause swelling or inflammation of the internal kidney structures (specifically, the glomeruli).
Nephritic syndrome is a type of glomerulonephritis.
# What are the s... | Nephritic syndrome (patient information)
For the WikiDoc page for this topic, click here
Editors-in-Chief: C. Michael Gibson, M.S., M.D. Associate Editor-In-Chief: Ujjwal Rastogi, MBBS [1]
# Overview
Acute nephritic syndrome is a group of disorders that cause swelling or inflammation of the internal kidney structure... | https://www.wikidoc.org/index.php/Nephritic_syndrome_(patient_information) | |
ccba466af92d2a344aa81d04f9e6234b7714850c | wikidoc | Neurogenic bladder (patient information) | Neurogenic bladder (patient information)
For the WikiDoc page for this topic, click here
# Overview
Neurogenic bladder is a urinary problem in which the bladder does not empty properly due to a neurological condition.
# What are the symptoms of Neurogenic bladder?
The specific symptoms depend on the underlying neurol... | Neurogenic bladder (patient information)
For the WikiDoc page for this topic, click here
Editors-in-Chief: C. Michael Gibson, M.S., M.D. Associate Editor-In-Chief: Ujjwal Rastogi, MBBS [1]
# Overview
Neurogenic bladder is a urinary problem in which the bladder does not empty properly due to a neurological condition.... | https://www.wikidoc.org/index.php/Neurogenic_bladder_(patient_information) | |
58eb3e3b7e3cc6e4669ec2df2ec6a27d1305b837 | wikidoc | Neurogenic locus notch homolog protein 4 | Neurogenic locus notch homolog protein 4
Neurogenic locus notch homolog 4 also known as notch 4 is a protein that in humans is encoded by the NOTCH4 gene located on chromosome 6.
# Gene
An alternative splice variant of the NOTCH4 gene has been described, but its biological significance has not been determined.
# Stru... | Neurogenic locus notch homolog protein 4
Neurogenic locus notch homolog 4 also known as notch 4 is a protein that in humans is encoded by the NOTCH4 gene located on chromosome 6.[1]
# Gene
An alternative splice variant of the NOTCH4 gene has been described, but its biological significance has not been determined.[2]
... | https://www.wikidoc.org/index.php/Neurogenic_locus_notch_homolog_protein_4 | |
0716896b09a4aebe97930800b70d1e3bfe2f7bba | wikidoc | Niacin/Simvastatin clinical pharmacology | Niacin/Simvastatin clinical pharmacology
# Clinical Pharmacology
## Pharmacodynamics
A variety of clinical studies have demonstrated that elevated levels of Total-C, LDL-C, and Apo B promote human atherosclerosis. Similarly, decreased levels of HDL-C are associated with the development of atherosclerosis. Epidemiolog... | Niacin/Simvastatin clinical pharmacology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Clinical Pharmacology
## Pharmacodynamics
A variety of clinical studies have demonstrated that elevated levels of Total-C, LDL-C, and Apo B promote human atherosclerosis. ... | https://www.wikidoc.org/index.php/Niacin/Simvastatin_clinical_pharmacology | |
1c6421b8bcb95a7e899804b2ae6b21acfe89dcc9 | wikidoc | Niacin/Simvastatin indications and usage | Niacin/Simvastatin indications and usage
# Indications and Usage
Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Drug therapy is indicated as an adjunct ... | Niacin/Simvastatin indications and usage
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Indications and Usage
Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk fo... | https://www.wikidoc.org/index.php/Niacin/Simvastatin_indications_and_usage | |
9312412ce43a3f6e416d04b9f8102e31376d9a3e | wikidoc | Niacin/lovastatin nonclinical toxicology | Niacin/lovastatin nonclinical toxicology
# Nonclinical Toxicology
## Carcinogenesis, Mutagenesis, Impairment of Fertility
No studies have been conducted with ADVICOR regarding carcinogenesis, mutagenesis, or impairment of fertility.
### Niacin
Niacin, administered to mice for a lifetime as a 1% solution in drinking ... | Niacin/lovastatin nonclinical toxicology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
# Nonclinical Toxicology
## Carcinogenesis, Mutagenesis, Impairment of Fertility
No studies have been conducted with ADVICOR regarding carcinogenesis, mutagenesis, or impair... | https://www.wikidoc.org/index.php/Niacin/lovastatin_nonclinical_toxicology | |
e4a444c5383a5ee13634f33cc311d64f1cd03b37 | wikidoc | Nitrofurantoin dosage and administration | Nitrofurantoin dosage and administration
# Dosage and Administration
Macrobid capsules should be taken with food.
Adults and Pediatric Patients Over 12 Years: One 100 mg capsule every 12 hours for seven days.
HOW SUPPLIED
Macrobid is available as 100 mg opaque black and yellow capsules imprinted “(Band) Macrobid (Band... | Nitrofurantoin dosage and administration
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
# Dosage and Administration
Macrobid capsules should be taken with food.
Adults and Pediatric Patients Over 12 Years: One 100 mg capsule every 12 hours for seven days.... | https://www.wikidoc.org/index.php/Nitrofurantoin_dosage_and_administration | |
d4e5144a0ad878d61aabc36dbad77546ad9c3ac8 | wikidoc | Normalisation (people with disabilities) | Normalisation (people with disabilities)
# Overview
“The normalization principle means making available to all ] people patterns of life and conditions of everyday living which are as close as possible to the regular circumstances and ways of life or society.” (Bengt Nirje, The basis and logic of the normalisation pri... | Normalisation (people with disabilities)
# Overview
“The normalization principle means making available to all [people with disabilities]] people patterns of life and conditions of everyday living which are as close as possible to the regular circumstances and ways of life or society.” (Bengt Nirje, The basis and logi... | https://www.wikidoc.org/index.php/Normalisation_(people_with_disabilities) | |
0b050a7e58983bb7334d994465f20b7489476875 | wikidoc | Olmesartan Medoxomil-Hydrochlorothiazide | Olmesartan Medoxomil-Hydrochlorothiazide
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The edu... | Olmesartan Medoxomil-Hydrochlorothiazide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vignesh Ponnusamy, M.B.B.S. [2]
# Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcar... | https://www.wikidoc.org/index.php/Olmesartan_Medoxomil-Hydrochlorothiazide | |
e01314c8b0d6f8d371bacd0224e3f939a5216b08 | wikidoc | Oxytocin injection (patient information) | Oxytocin injection (patient information)
# About your treatment
Your doctor has ordered oxytocin, a hormone, to stimulate contractions of the uterus and smooth muscle tissue. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a nee... | Oxytocin injection (patient information)
Template:Drug header
# About your treatment
Your doctor has ordered oxytocin, a hormone, to stimulate contractions of the uterus and smooth muscle tissue. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that w... | https://www.wikidoc.org/index.php/Oxytocin_injection | |
5bf69851d378a0379643a3126bb7d740efff3eb6 | wikidoc | P53 response element gene transcriptions | P53 response element gene transcriptions
"A p53 consensus DNA RE is composed of a tandem of two decameric palindromic sequences (half-sites) 5′-RRRCWWGYYY-3′, where R = purine, Y = pyrimidine and W is either A or T. There is a variability in composition of p53 REs, thus two half-sites can be separated by a spacer DNA, ... | P53 response element gene transcriptions
Associate Editor(s)-in-Chief: Henry A. Hoff
"A p53 consensus DNA RE is composed of a tandem of two decameric palindromic sequences (half-sites) 5′-RRRCWWGYYY-3′, where R = purine, Y = pyrimidine and W is either A or T. There is a variability in composition of p53 REs, thus two... | https://www.wikidoc.org/index.php/P53_response_element_gene_transcriptions | |
c83c318c494b2ad0b382ee1f93cf3616dd86198d | wikidoc | P63 DNA-binding site gene transcriptions | P63 DNA-binding site gene transcriptions
"p63 bound preferentially to DNA fragments conforming to the 20 bp sequence 5'-RRRC(A/G)(A/T)GYYYRRRC(A/T)(C/T)GYYY-3'."
# Human genes
# Consensus sequences
The apparent consensus sequence is (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T).
# p63 samplings
Copying an apparent cons... | P63 DNA-binding site gene transcriptions
Associate Editor(s)-in-Chief: Henry A. Hoff
"p63 bound preferentially to DNA fragments conforming to the 20 bp sequence 5'-RRRC(A/G)(A/T)GYYYRRRC(A/T)(C/T)GYYY-3'."[1]
# Human genes
# Consensus sequences
The apparent consensus sequence is (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T... | https://www.wikidoc.org/index.php/P63_DNA-binding_site_gene_transcriptions | |
b0c62f8aaa71faa80e28c48f5d12a50f6c1bd67a | wikidoc | Pulmonary Langerhans' cell histiocytosis | Pulmonary Langerhans' cell histiocytosis
Synonyms and keywords: PLCH
# Overview
# Historical Perspective
- was first discovered by , a , in during/following .
- In , mutations were first identified in the pathogenesis of .
- In , the first was developed by to treat/diagnose .
# Classification
- may be classifi... | Pulmonary Langerhans' cell histiocytosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Your Name
Synonyms and keywords: PLCH
# Overview
# Historical Perspective
- [Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [eve... | https://www.wikidoc.org/index.php/PLCH | |
b4ef9f500c56a8d900f4a05f96a509eb27a0b2f9 | wikidoc | Pancreatic neuroendocrine tumor | Pancreatic neuroendocrine tumor overview
# Overview
Pancreatic neuroendocrine tumors (PanNETs, PETs, or PNETs), often referred to as "islet cell tumors", or "pancreatic endocrine tumors" are neuroendocrine neoplasms that arise from cells of the endocrine (hormonal) and nervous system within the pancreas.
PanNETs are a... | Pancreatic neuroendocrine tumor overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Pancreatic neuroendocrine tumors (PanNETs, PETs, or PNETs), often referred to as "islet cell tumors", or "pancreatic endocrine tumors" are neuroendocrine neoplasms that arise from cells of the endocrine (hormonal) a... | https://www.wikidoc.org/index.php/Pancreatic_neuroendocrine_tumor_overview | |
e4ff099ba715bed5f9db92f6905898a0293f67aa | wikidoc | Paroxysmal AV Block physical examination | Paroxysmal AV Block physical examination
# Overview
There are no specific physical examination findings seen in patients with paroxysmal AV block.
# Physical Examination
There are no specific physical examination findings seen in patients with paroxysmal AV block.
## Appearance of the Patient
- Patients with paroxys... | Paroxysmal AV Block physical examination
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akash Daswaney, M.B.B.S[2]
# Overview
There are no specific physical examination findings seen in patients with paroxysmal AV block.
# Physical Examination
There are no specific physical examin... | https://www.wikidoc.org/index.php/Paroxysmal_AV_Block_physical_examination | |
259e3287efb98e85c477c66c797dd176f31e065a | wikidoc | Pegylated interferon alfa-2a description | Pegylated interferon alfa-2a description
# Description
PEGASYS, peginterferon alfa-2a, is a covalent conjugate of recombinant alfa-2a interferon (approximate molecular weight 20,000 daltons) with a single branched bis-monomethoxy polyethylene glycol (PEG) chain (approximate MW 40,000 daltons). The PEG moiety is linke... | Pegylated interferon alfa-2a description
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Description
PEGASYS, peginterferon alfa-2a, is a covalent conjugate of recombinant alfa-2a interferon (approximate molecular weight [MW] 20,000 daltons) with a single branched bis-monomethoxy polyethylene glycol (PEG) chain ... | https://www.wikidoc.org/index.php/Pegylated_interferon_alfa-2a_description | |
95b10d37fb820c63b4173d3b8610adeb7ab600af | wikidoc | Penicillin G potassium adverse reactions | Penicillin G potassium adverse reactions
# Adverse Reactions
## Body as a whole
The Jarisch-Herxheimer reaction is a systemic reaction, that may occur after the initiation of penicillin therapy in patients with syphilis or other spirochetal infections (i.e., Lyme disease and Relapsing fever). The reaction begins one ... | Penicillin G potassium adverse reactions
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
# Adverse Reactions
## Body as a whole
The Jarisch-Herxheimer reaction is a systemic reaction, that may occur after the initiation of penicillin therapy in patients w... | https://www.wikidoc.org/index.php/Penicillin_G_potassium_adverse_reactions | |
4c8914029f9a4c2f9d6589f80bbc2d915b291a44 | wikidoc | Penicillin V potassium adverse reactions | Penicillin V potassium adverse reactions
# Adverse Reactions
Although the incidence of reactions to oral penicillins has been reported with much less frequency than following parenteral therapy, it should be remembered that all degrees of hypersensitivity, including fatal anaphylaxis, have been reported with oral peni... | Penicillin V potassium adverse reactions
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
# Adverse Reactions
Although the incidence of reactions to oral penicillins has been reported with much less frequency than following parenteral therapy, it should be ... | https://www.wikidoc.org/index.php/Penicillin_V_potassium_adverse_reactions | |
eaccc3b9f3debb89f6d5956731f122e1077d4b2c | wikidoc | Peridontal disease (patient information) | Peridontal disease (patient information)
# Overview
Many adults in the U.S. currently have some form of the disease. Periodontal diseases range from simple gum inflammation to serious disease that results in major damage to the soft tissue and bone that support the teeth. In the worst cases, teeth are lost. Whether yo... | Peridontal disease (patient information)
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
# Overview
Many adults in the U.S. currently have some form of the disease. Periodontal diseases range from simple gum inflammation to serious disease that results in major damage to the soft tissue and bone that support the t... | https://www.wikidoc.org/index.php/Peridontal_disease_(patient_information) | |
b6aa70903e2e2a3d7307ab192a5a0142f491a995 | wikidoc | Periodic table (electron configurations) | Periodic table (electron configurations)
- Grayed out electron numbers indicate subshells that are filled to their maximum.
- Configurations of elements with light gray background are uncertain or not available.
Configurations that are unavailable are guessed to be similar to the element directly above on the Periodic ... | Periodic table (electron configurations)
Template:Element color legend
- Grayed out electron numbers indicate subshells that are filled to their maximum.
- Configurations of elements with light gray background are uncertain or not available.
Configurations that are unavailable are guessed to be similar to the element ... | https://www.wikidoc.org/index.php/Periodic_table_(electron_configurations) | |
209003ba66221cf5a5e77b5f91ddb464600e0ee9 | wikidoc | Phosphoribosylaminoimidazole carboxylase | Phosphoribosylaminoimidazole carboxylase
Phosphoribosylaminoimidazole carboxylase (or AIR carboxylase) is an enzyme involved in nucleotide biosynthesis and in particular in purine biosynthesis. It catalyzes the conversion of 5'-phosphoribosyl-5-aminoimidazole ("AIR") into 5'-phosphoribosyl-4-carboxy-5-aminoimidazole ("... | Phosphoribosylaminoimidazole carboxylase
Phosphoribosylaminoimidazole carboxylase (or AIR carboxylase) is an enzyme involved in nucleotide biosynthesis and in particular in purine biosynthesis. It catalyzes the conversion of 5'-phosphoribosyl-5-aminoimidazole ("AIR") into 5'-phosphoribosyl-4-carboxy-5-aminoimidazole (... | https://www.wikidoc.org/index.php/Phosphoribosylaminoimidazole_carboxylase | |
d33df26d637469c26afab19716fa45a70dffc0ec | wikidoc | Physical Therapy for Arthritis Treatment | Physical Therapy for Arthritis Treatment
In the earlier days, maintaining the well-being of arthritis patients was a challenging task. But in recent times, physical therapy has proven to be an ideal solution for arthritis treatment as it improves mobility, reduces dizziness and pain, and improves balance, strength and ... | Physical Therapy for Arthritis Treatment
In the earlier days, maintaining the well-being of arthritis patients was a challenging task. But in recent times, physical therapy has proven to be an ideal solution for arthritis treatment as it improves mobility, reduces dizziness and pain, and improves balance, strength and... | https://www.wikidoc.org/index.php/Physical_Therapy_for_Arthritis_Treatment |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.