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(MENAFN- PR Newswire)
Family Entertainment platform Company Names Sean Naughton to Chief financial Officer and Promotes Jessica McDonald to Vice President of Marketing of Altitude Trampoline Park
DALLAS, Oct. 15, 2024 /PRNewswire/ -- Indoor Active Brands , a platform company that focuses on indoor entertainment concepts, is pleased to announce the appointment of Sean Naughton as Chief Financial Officer (CFO) and the Promotion of Jessica McDonald to Vice President of Marketing at Altitude Trampoline Park. These leadership changes reflect the company's commitment to strategic growth and development within the family entertainment industry.
Prior to joining Indoor Active Brands, Naughton served as Vice President of Strategy and Financial Planning Analysis at CEC Entertainment, where he honed his expertise in financial forecasting, budgeting, competitive analysis, and performance metrics. As CFO of Indoor Active Brands, Naughton will lead the company's financial strategy, focusing on protecting stakeholder investments while driving sustainable growth and expansion.
"Working in the family entertainment industry has always been a rewarding experience, bringing joy to both kids and families," said Naughton. "At Indoor Active Brands, my focus is on driving growth for both Altitude Trampoline Park and The Pickle Pad. I'm excited to expand Altitude's footprint while helping The Pickle Pad achieve the same level of success."
In addition to Naughton's appointment, Jessica McDonald has been promoted to Vice President of Marketing at Altitude Trampoline Park. Since joining the brand in October 2021, McDonald has played a crucial role in shaping its marketing strategy across various digital and traditional media platforms, including TikTok, Reels, and LinkedIn. Her leadership has driven key initiatives such as membership programs, birthday parties, gift card sales, and product development, all of which have contributed to the brand's revenue growth.
"Jessica has been a vital part of our success at Altitude, and we wouldn't be where we are today without her contributions. It's always rewarding to promote from within, and we're thrilled to recognize Jessica's hard work with this well-deserved promotion," said Mike Rotondo, CEO of Indoor Active Brands. "As Altitude continues to grow and we ramp up efforts with The Pickle Pad, we're focused on building a leadership team that can support our vision. With Sean's financial expertise and Jessica's marketing acumen, we are well-positioned for success."
Established by NRD Capital, Indoor Active Brands utilizes industry experience in the family entertainment and restaurant industries to support and assist its franchisees. Its portfolio includes Altitude Trampoline Park, a leading family entertainment destination, and its newest venture, The Pickle Pad, an indoor pickleball playground featuring a chef-inspired restaurant, bar, and yard games for all ages.
Altitude Trampoline Park is actively seeking qualified candidates to help grow its footprint throughout the U.S. in Kansas City, MO, Minneapolis, MN, Las Vegas, NV,
Denver, CO, among others. To learn more about franchise opportunities and upcoming store openings, contact Mike Stout at [email protected]
or visit .
The Pickle Pad is also seeking qualified candidates to help grow its footprint throughout the U.S. specifically in the Southeast and Midwest regions. To learn more about franchise opportunities, contact
Robert Morris, Vice President of Development, at
[email protected]
or visit
.
About Altitude Trampoline Park
Altitude Trampoline Park is a premier family-friendly entertainment destination offering cutting-edge attractions and Party Packages to accommodate all of life's most meaningful celebrations. Altitude is the home for active family fun! The brand offers children's birthday party packages and special events, providing two hours of unlimited jump time and access to all of Altitude's attractions, including trampolines, playgrounds, basketball, dodgeball, interactive games and more. Altitude's successful $10 Endless Jumps Membership program allows children unlimited access to the brand's attractions for a fixed price, offering a great way for families to stay together and play together all year long. Nearing 100 locations worldwide, Altitude parks are centrally located and easily accessible, making it the convenient, budget friendly choice for families in 2024. More information can be found at
altitudetrampolinepark .
About The Pickle Pad:
The Pickle Pad is an indoor pickleball and entertainment experience featuring multiple courts, spectator seating and open green spaces with social and lawn games. Each location also offers Crave Social Eatery, a full-service, chef-inspired restaurant where guests can dine in the restaurant or courtside. The space is welcoming and offers something for everyone and any athletic level. The Pickle Pad is part of Indoor Active Brands, which also owns Altitude Trampoline Park, one of the largest entertainment brands in the world. For more information about The Pickle Pad visit
About Indoor Active Brands
Indoor Active Brands is a platform company focused on owning and operating franchising concepts in the indoor family entertainment industry. Created by NRD Capital, Indoor Active Brands currently consists of Altitude Trampoline Park and The Pickle Pad. Indoor Active Brands leverages years of experience in the family entertainment and restaurant industries to provide unmatched support for its franchisees. For more information about Indoor Active Brands visit .
Media Contact:
Andrea Mazzola, Fish Consulting
[email protected] | 956-893-9150
SOURCE Indoor Active Brands
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Last week, it was reported that Raul Gonzalez is to leave his position as Real Madrid Castilla head coach at the end of the season. Despite rejecting numerous proposals from other clubs, the Los Blancos legend is to depart the role that he has been in since 2019.
Relevo has revealed more details of Raul’s situation. Although there has been no definitive confirmation of his expected departure, it is set to take place next summer. His contract is not to be renewed, with some sources stating that Jose Angel Sanchez, Real Madrid’s Chief Executive Officer, has told the 47-year-old that his time is up.
The report also claims that Raul has very little support” from those within Real Madrid and Castilla, which is another reason why he will be let go.
Alvaro Arbeloa, who has been Real Madrid’s U19 manager for the last couple of seasons, is expected to make the step up to Castilla from 2025-26 onwards. It remains to be seen whether Raul will go, although it’s unlikely that he’ll be short of offers. | https://www.football-espana.net/2024/10/15/real-madrid-legend-has-very-little-support-from-within-as-expected-2025-departure-looms | 2024-10-15T17:56:18Z |
With eight goals as a substitute since February 2023, he leads the league in this category.
With matches in the English top flight last season averaging nearly to 101 minutes and in-play time increasing by an average of three minutes and 45 seconds, substitutes have more chances to affect the outcome of games.
It’s not surprising that Justin Kluivert's winning goal for Bournemouth against Crystal Palace in April 2024 exceeded the previous record of 132 goals scored by substitutes, which was established in the 2022/2023 season.
The introduction of five substitutions since 2020 has also transformed the strategic landscape regarding betting on goal scorers.
This weekend's fixtures provide a prime context to explore which games might be decided by super-subs.
Odds courtesy of Betway. Correct at time of publishing and subject to change.
Tottenham vs West Ham: A Derby Ripe for Tactical Nuance
In the Premier League, second-half performances have become increasingly pivotal, with Arsenal leading by netting nine goals after the break this season.
Closely following are Chelsea, Aston Villa, and Brighton, each with seven goals scored in the second half.
Spurs, despite their strong home record, have shown a clear vulnerability in the second half, having conceded six goals.
This contrasts notably with West Ham’s impressive second-half record on the road, where they've scored four goals without conceding. For the Hammers, Danny Ings presents a potent threat.
Twenty of Ings’ last 23 appearances for West Ham have been as a substitute, and the former Aston Villa forward has already scored the Hammers’ 95th equaliser at Craven Cottage this season.
With a conversion rate of 50% (one goal from two shots, both on target), Ings is a prime candidate to capitalise on Tottenham's defensive lapses in the closing stages of the game.
Fulham vs Aston Villa: The Duran’s effect
Aston Villa’s standout performer Jhon Duran, has made a name for himself with his incredible ability to score crucial goals after coming off the bench. His record speaks volumes: five of his six goals this season have been as a substitute, making him an invaluable asset in tight match situations.
With Fulham having shown a tendency to concede late goals (three after the 75th minute), Villa's tactical setup could be perfectly poised to unleash the Colombian striker when the game opens up.
Duran, who has a 40% conversion rate, highlights the club's late-game prowess, suggesting an increased likelihood that this game will end with Both Teams to Score and over 2.5 Goals.
Wolves vs Man City: Guardiola’s Rotational Masterpiece
Manchester City are expected to extend their Premier League unbeaten run when they visit Wolverhampton, with Pep Guardiola’s use of substitutes likely to be vital as they prepare for their return to Champions League football.
City tops the league in overall scoring, but has struggled to replicate this success after the break in away matches, scoring just twice.
Wolverhampton Wanderers, on the other hand, have struggled defensively, conceding the most second-half goals with a total of 12, seven of which came at Molineux.
Furthermore, Manchester City leads the league with five goals scored after the 75th minute, while Arsenal, Aston Villa, Newcastle, and Tottenham each follow with three late goals.
Jeremy Doku has come off the bench 13 times for City since 2023/2024 and taken six shots in the current campaign, scoring during the last matchday against Fulham after coming on for Jack Grealish.
Liverpool vs Chelsea: late goals likely
The highly anticipated clash of Liverpool and Chelsea is another game where substitute power could play a pivotal role.
Both clubs have shown competence in second-half performances, with Chelsea maintaining an unbeaten away record post-break and Liverpool boasting squad depth capable of overturning results late in games.
Chelsea has scored six times away from home in second halves, speaking to their ability to recalibrate and adapt as matches evolve.
Christopher Nkunku could be a smart pick, considering his 25% conversion rate in the Premier League, along with his recent goals in the Conference League, and for France during the international break.
Liverpool possess a wealth of attacking options, with a player like Dawin Nuñez (eight goals for The Reds as a substitute in all competitions), potentially turning the tide late in games. | https://www.goal.com/en-za/betting/duran-duran-the-premier-league-s-super-subs-bettors-should-back/blt0d5c5e28e5adebe9 | 2024-10-15T17:56:15Z |
Jerry Jones celebrated his 82nd birthday on Sunday by watching his Dallas Cowboys get dismantled by the Detroit Lions 47-9. Two days later, he directed his frustrations towards a pair of hosts on the team's flagship radio station.
Following an offseason that saw the Cowboys spend little on free agents and save big money spending on their own star players —CeeDee Lamb and Dak Prescott — Jones did not take fondly to being asked why he wasn't more active on improving the roster.
Jones' annoyance with the line of questioning had him appearing to threaten the jobs of 105.3 FM's Shan Shariff, R.J. Choppy and Bobby Belt.
This is not your job. Your job isn't to let me go over all the reasons that I did something and I'm sorry that I did it," Jones said. That's not your job. I'll get somebody else to ask these questions. I'm not kidding. You're not going to figure out what the team is doing right or wrong. If you are, or any five or 10 like you, you need to come to this [NFL owner's] meeting I'm going to today with 32 teams here, you're geniuses.
"Ya'll really think you're gonna sit here with a microphone and tell me all of the things that I've done wrong without going all over the rights? Listen, we both know we're talking to a lot of great fans and a lot of great listeners. And I'm very sorry for what happened out there Sunday. I'm sick about what happened Sunday.
"One of the stupidest things I've ever done, that anybody had ever analyzed is buy the Cowboys. It was an idiot that did that. So idiot things can turn into good decisions. Smart things can turn into bad decisions. The facts are that when you make one, you don't really know if it's going to be good or not at the time. You want some conversation this morning, you're getting it."
The Cowboys have their bye in Week 7 before returning to face the San Francisco 49ers on Sunday night in Week 8. There was already going to be a heavy discussion about the construction of Dallas' roster considering their mediocre start and that the NFL's highest-paid quarterback is tied for second in interceptions (6), has an 85.4% passer rating and has been sacked the fifth-most times (16) — not to mention they've lost four consecutive games at AT&T Stadium.
And now the Cowboys will gobble up headlines during an off week — which makes you think Jones knew what he was doing here. He's always been a salesman.
Jones said after Sunday's loss he was happy the bye week was coming as it will give them time to fix the numerous areas that need improvement. Micah Parsons and DeMarcus Lawrence will likely remain out through the bye, further hobbling a 25th-ranked defense that has given up the sixth-most rushing yards and allowed the third-most points through six weeks.
As for change? That's not coming for any part of the Cowboys' roster. Head coach Mike McCarthy's job is safe as Jones reiterated Tuesday by saying in-season coaching changes are "usually ineffective. They just aren't good."
On the field, Jones trusts in his players — his "outstanding personnel" as he put it — to turn around an uninspired start to the season.
"Well, first of all, where you going to go to get any players? Seriously? Where are you going to go to get any players for next week against San Francisco?" Jones said. "Now, No. 1, I've seen these players. I've seen every single one of them execute like you want the plays to be executed and do their job within the role. That didn't happen the other day, and we paid the consequences for it. But I've seen the players do it." | https://www.wftv.com/news/national/jerry-jones-objects/3XSYJLAHP76APG3MMXDXOVXLMM/ | 2024-10-15T17:56:18Z |
The following is an excerpt from the latest edition of Yahoo's fantasy football newsletter, Get to the Points! If you like what you see, you can subscribe for free here.
Fantasy managers will spend the next 24 hours working the waiver wire, but that's obviously just part of the process. In most instances, you also have to make a corresponding drop. And we'd like to help you make those difficult cuts.
Most fantasy advice will never be one size fits all, and that's especially true for a cut list. You need to apply this to your situation and the context of your league. A nifty stash in one league could be a see-you-later player in a different room. And remember, if you never make a regretful cut during the season, you're probably playing far too conservatively.
Isaiah Likely, TE, Ravens (59% rostered)
I have a few fantasy shares of Likely, and I'm not eager to give them up. But we have to accept that he's merely a contingency-value stash at tight end these days, not someone you can play. He has just nine catches since the blowup season opener. Unless Mark Andrews gets hurt, Likely can't be trusted in lineups. And in the teeth of bye season, that might make him a drop now.
Dontayvion Wicks, WR, Packers (47% rostered)
You used good process when you added Wicks, but he didn't come through in his last two opportunities, and now the receiving room is healing up. The Packers also have two talented backs and a tight end of note. Wicks is also dealing with a shoulder injury, giving him week-to-week status. In most formats, it's not worth the wait.
Trey Sermon, RB, Colts (48% rostered)
Jonathan Taylor probably isn't long off, even if he can't play in Week 7. But Sermon has a more immediate issue — Tyler Goodson is clearly outplaying him. Surely this isn't lost on the Indianapolis coaching staff.
Antonio Gibson, RB, Patriots (49% rostered)
He flopped in his starting opportunity last week (13 carries, 19 yards) and the Patriots will go back to Rhamondre Stevenson when healthy, no matter how much he fumbles. And some of New England's rushing production will also be distributed to athletic and resourceful rookie QB Drake Maye.
Jerome Ford, RB, Browns (73% rostered)
He's dealing with a balky hamstring, the offense is shipwrecked by poor blocking and QB play, and Nick Chubb might return this week. Ford was a fantasy dud most of the year, and while much of it wasn't his fault, he has a capped ceiling.
Daniel Jones, QB, Giants (21% rostered)
He made sense as a Week 6 sleeper, even though his home/road splits are starting to become too large to ignore (Jones, for some reason, plays poorly in New Jersey). It's a home date against Philly this week, and then a trip to Pittsburgh. Even with Malik Nabers expected back, we hope you have a better QB option to navigate the bye weeks. | https://www.hits973.com/news/national/fantasy-football/FC4M6YSYJ5WC6BJCO3H3DEJPM4/ | 2024-10-15T17:56:19Z |
Retired Judge Pat Carroll Wins Award
Ohio Bar Honors Judge Patrick Carroll and the Summit County Juvenile Court's Multidisciplinary Representation Team With Awards for Excellence and Innovation at Ohio Judicial Conference Annual Meeting
In recognition of judicial excellence and innovation, Ohio State Bar Association 2024-2025 President Dan Griffith presented the 2024 Thomas J. Moyer Award for Judicial Excellence to Retired Lakewood Municipal Court Judge Patrick Carroll and the 2024 Innovative Court Programs and Practices Award to the Multidisciplinary Representation Team at the Summit County Juvenile Court, led by Judge Linda Teodosio. Both awards were presented as part of the Ohio Judicial Conference annual meeting at the Hilton Easton Columbus on Sept. 19.
The Moyer award was established in 2010 by the Ohio Bar in honor of the late Chief Justice, who was posthumously given the inaugural award. It seeks to recognize a current or former Ohio state or federal judge in the Moyer mold who displays outstanding qualities of judicial excellence including integrity, fairness, open-mindedness, knowledge of the law, professionalism, ethics, creativity, sound judgment, courage and decisiveness.
For this year’s selection committee, Judge Patrick Carroll checked all the boxes and more. Though he retired from the Lakewood Municipal Court in 2022 after more than 30 years of distinguished service on the bench, he continues to give back by sharing his knowledge and experience as one of Ohio’s most preeminent educators of fellow judges.
A lifelong learner and a lifelong resident of Lakewood, Judge Carroll graduated from the Cleveland-Marshall College of Law, where he would later have an opportunity to serve as an adjunct professor. He began his career as a clerk to 8th District Court of Appeals Judge John Corrigan. Over the years, he served in private practice and as a prosecutor for Cuyahoga County, where his primary clients were the common pleas and juvenile courts and he advocated for judges in civil litigation cases.
It was in 1990 that he was appointed to the Lakewood Municipal Court. He was subsequently elected and re-elected for a total of six terms, earning a reputation for impartiality, professionalism and compassion. Judge Carroll was an early adopter as courts began to take a more proactive role in treating substance abuse. He counts his work with, and in support of defendants struggling with addiction as some of the most rewarding of his career.
While still a sitting judge, Carroll became a frequent presenter on behalf of the Ohio Judicial Conference, conducting 10 webinars over the course of eight months during the pandemic when in-person continuing legal education was not a possibility. He continues to serve on the committee to plan education for judges, as co-chair of the jury instructions committee and recently took on the role as Ohio Judicial Outreach Liaison to the American Bar Association, where he is drafting a monthly newsletter to educate colleagues about recent case law around impaired driving, alcohol and drugs.
“Judge Carroll is highly deserving of this recognition. Not only has he been an outstanding trial judge and public servant, but he continues to embody judicial excellence through his generosity of time, talent and knowledge that has helped countless fellow judges hone their craft," President Griffith said.
By Maggie Ostrowski Ohio Bar Staff, OSBA News
Publisher, Lakewood Observer, Inc. | https://lakewoodobserver.com/read/2024/10/15/retired-judge-pat-carroll-wins-award | 2024-10-15T17:56:22Z |
Updated October 11, 2024 at 07:46 AM ET
A Japanese anti-nuclear weapons group made up of survivors of the atomic bombings in Japan during World War II has won the 2024 Nobel Peace Prize.
The Norwegian Nobel Committee said it has awarded the Japanese organization Nihon Hidankyo "for its efforts to achieve a world free of nuclear weapons and for demonstrating through witness testimony that nuclear weapons must never be used again," sending a message to countries that are considering acquiring or threatening to use them.
Committee Chair Jørgen Watne Frydnes said Nihon Hidankyo, made up of survivors of the August 1945 nuclear bombings of Hiroshima and Nakasaki by the United States, has been instrumental in the global movement that has kept nuclear weapons from being used in conflict for 80 years.
“These historical witnesses have helped to generate and consolidate widespread opposition to nuclear weapons around the world by drawing on personal stories, creating educational campaigns based on their own experience and issuing urgent warnings against the spread of nuclear weapons,” he said.
Frydnes said thanks to their work, nuclear weapons have been stigmatized as morally unacceptable. But he added that the long-held "nuclear taboo" is now under pressure.
“The nuclear powers are modernizing and upgrading their arsenals,” he said. “New countries appear to be preparing to acquire weapons, and threats are being made to use nuclear weapons as part of ongoing warfare.”
At a press conference in Hiroshima, Nihon Hidankyo's co-chair, Toshiyuki Mimaki, 81, held back tears and pinched his cheeks when the award was announced. "I can't believe it's real" he told reporters.
Mimaki is a Hiroshima survivor and said the award helped recognize the group's work. “It would be a great force to appeal to the world that the abolition of nuclear weapons can be achieved," he said.
He said the idea that nuclear weapons bring peace to the world is wrong.
“It has been said that because of nuclear weapons, the world maintains peace. But nuclear weapons can be used by terrorists,” he said. “For example, if Russia uses them against Ukraine, Israel against Gaza, it won’t end there. Politicians should know these things.”
The Nobel Committee’s award seemed to be a message for Iran, who some believe is trying to develop nuclear weapons, to North Korea, a nuclear power thought to be trying to expand its arsenal, as well as to Russia, which has lowered the threshold for when it would launch a nuclear attack.
Many had expected this year’s prize to be linked to the wars in Gaza, Ukraine or Sudan. Those conflicts were top of mind when the Nobel Committee made its decision, Frydnes said.
“When we look at the developments and the conflicts around the world, we see how crucial it is to uphold a nuclear taboo," he said. "To uphold the norm, saying nuclear weapons would never be used again.”
Frydnes said 120,000 inhabitants of Hiroshima and Nagasaki had been incinerated or had died in the months and years that followed from burns and radiation.
“Today’s nuclear weapons have far greater destructive power,” he said. “They can kill millions and would impact the climate catastrophically. Nuclear war could destroy our civilization.”
The award was announced at the Norwegian Nobel Institute in Norway’s capital Oslo.
Copyright 2024 NPR | https://www.ideastream.org/2024-10-11/a-japanese-organization-of-atomic-bombing-survivors-wins-the-2024-nobel-peace-prize | 2024-10-15T17:56:23Z |
(MENAFN- PR Newswire)
New solution is designed to help financial services institutions reduce the risk of fraudulent activities while delivering a secure total experience
SAN FRANCISCO, Oct. 15, 2024 /PRNewswire/ -- BeyondID , a leading managed identity solutions provider (MISP), today announced a fraud prevention solution for its customers. Fraud prevention will be part of the company's managed identity solutions and help customers to deliver a secure total experience. With these new fraud prevention capabilities, BeyondID can combat modern identity fraud scams with strong identity security.
Financial institutions are the top target for digital identity fraud, as hackers frequently target organizations with direct access to monetary resources and sensitive data. According to the Financial Crimes Enforcement Network (FinCEN), 42% of Bank Secrecy Act reports were related to identity in 2021, indicating approximately $212 billion in suspicious activity.
Fraud prevention and digital identity are closely linked and when organizations focus on both, it can dramatically minimize the impact of breaches. When every service requested by every user, whether human or machine, is authenticated, authorized, and encrypted end-to-end, the organization significantly reduces the risk of fraudulent activities.
"As organizations become more interconnected, they face the growing challenge of digital identity fraud-where attackers exploit vulnerabilities across multiple systems to gain unauthorized access," said Arun Shrestha, CEO and co-founder of BeyondID. "With our advanced fraud prevention solutions, we can help our customers, especially those in the financial services industry, tackle the thorny challenges around digital identity security without sacrificing user experience."
The company's fraud prevention focus will be highlighted at
Oktane24 where Neeraj Methi, Vice President of Solutions, will lead a session titled "Combat Digital Identity Fraud: Enhancing Security and User Experience ." The session will be an opportunity for attendees to learn more about building a comprehensive identity strategy to balance robust protection with a seamless user experience.
Organizations interested in exploring fraud prevention through identity can learn more by watching BeyondID and Okta's joint fraud prevention webinar "Prevent Fraud in Financial Services with Identity, "
or downloading BeyondID's e-book " The War Against Fraud: Safeguarding Your Workforce & Customers. "
About BeyondID
BeyondID is a leading Managed Identity Solutions Provider (MISP). By delivering secure solutions and services that help manage digital identities, BeyondID enables organizations to control access to applications, data, networks, and devices while facilitating continuous regulatory compliance and ensuring seamless user experiences. BeyondID has created Secure Total Experiences for organizations like TDECU, Inception Health, Johnson Financial Group, Biogen, Northern Trust, and Cone Health. More information about BeyondID can be found at .
SOURCE BeyondID
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The usual suspects seem set to compete at the very top, but there are some teams who have their sights set on a top-half finish.
Fulham have perhaps been the biggest surprise at this stage. They are 7th in the table after amassing a total of 11 points. Bournemouth are also aiming to build on a positive first season. With the likes of Manchester United and West Ham wilting, there is an opportunity for each of these sides to break into the top 10.
Odds courtesy of 10bet. Correct at time of publishing and subject to change.
Fulham Aiming to Build on Superb Start
Fulham have established themselves in the Premier League since being promoted from the Championship in the 2021/22 season. They secured a 10th-place finish in their first campaign back in the top flight and are now eager to improve on that this year.
Marco Silva’s side have netted 10 goals thus far, more than the likes of Manchester United and Newcastle. Their xG of 13.86 suggests they should have scored even more. Only the current top four and Tottenham rank higher in that regard.
The Cottagers’ defence has also been solid. Only Liverpool have a better xGA than Fulham’s 7.37. However, they have underperformed that metric by conceding an average of 1.14 goals per game in the league.
The loss against Manchester City before the international break was Fulham’s first since the opening day of the season. Marco Silva will be delighted with the way his team played, as they finished the game with a superior xG to Pep Guardiola’s side.
Fulham face a difficult test in the form of Aston Villa this weekend, but home advantage could be key. Marco Silva’s side’s last outing at Craven Cottage was an impressive 3-1 win over Newcastle and they are yet to taste defeat on home turf this season.
Iraola’s Team Can Continue to Progress
Bournemouth made the decision to sack Gary O’Neil ahead of last season. Andoni Iraola was brought in and he has certainly made an impact. The Cherries made a slow start under the Spaniard, but they turned on the style after a couple of months and wound up finishing 12th.
Iraola’s side have had some difficult fixtures at the start of this campaign. They have already faced the likes of Liverpool, Chelsea and Newcastle. Bournemouth have another tough fixture when they host Arsenal this weekend, but they did manage to earn a point the last time they squared off against the Gunners.
Despite the difficult start, the Cherries’ underlying numbers are strong. They have the seventh-highest xG in the league with 13.8. They also rank in the top half of the league for xGA.
Dominic Solanke was a big loss in the summer, but Bournemouth have bolstered their attack with the signings of Evanilson, Enes Unal and Luis Sinisterra. Antoine Semenyo has also started the season well.
Andoni Iraola is also a huge asset for Bournemouth. The talented coach has made his team very difficult to play against. The Cherries tend to be aggressive without the ball and often opt to press intensely with man-to-man marking. Iraola also encourages his players to play balls in behind the opposition defence, exploiting some of the Premier League’s high defensive lines. | https://www.goal.com/en-za/betting/fulham-bournemouth-premier-league-top-ten-bet/bltc46516c1210862e4 | 2024-10-15T17:56:24Z |
- Fast Track Designation is designed to expedite FDA review of important new drugs to treat serious conditions and fill an unmet medical need.
- Fast Track Designation for LP-184 (STAR-001) recognizes Glioblastoma (GBM) as a serious condition impacting more than 13,000 U.S. adults each year and approximately 300,000 globally.
- A phase 1b/2a clinical trial for recurrent GBM is targeted to start in late 2024/early 2025.
- LP-184, which will be developed as STAR-001 for CNS and other neuro-oncology indications by Starlight Therapeutics, a wholly owned subsidiary of Lantern Pharma, has the potential to be the first new drug for treating GBM in more than 20 years.
DALLAS--(BUSINESS WIRE)--Lantern Pharma Inc. (NASDAQ: LTRN), an artificial intelligence (AI) company dedicated to developing cancer therapies and transforming the cost, pace, and timeline of oncology drug discovery and development, today announced that the FDA has granted Fast Track Designation for investigational drug candidate, LP-184, for treatment of Glioblastoma. LP-184 is currently in a Phase 1A clinical trial designed to evaluate the safety and tolerability of the synthetically lethal investigational drug candidate in a broad range of solid tumors, including Glioblastoma (GBM). LP-184 was optimized and advanced in part with Lantern’s AI platform, RADR®, to aid in the validation of mechanisms that could be exploited in the clinical setting to eradicate challenging cancers, and uncover insights in targeted patient populations. RADR® is Lantern’s AI platform for cancer therapy discovery, development and rescue with over 100 billion data points and aiding in the development of both Lantern’s portfolio and development initiatives with Lantern’s collaborators.
About GBM and the need for improved and novel therapies.
Glioblastoma (GBM) affects nearly 13,000 patients annually in the US and approximately 300,000 globally, with a mortality rate of 94%. Current standard of care therapies result in a life expectancy in GBM patients of less than 15 months. A major limitation to development of new drugs in the treatment of GBM is the need for potential drugs to have the ability to cross the blood brain barrier (BBB) as well as the ability to counteract the inherent and adaptive resistance of GBM cancer cells to temozolomide, the current standard of care in GBM. This resistance is largely derived from the expression of the DNA repair enzyme MGMT1. LP-184 activity is agnostic to MGMT expression, meaning it does not depend on the under or over-expression of MGMT in GBM and has shown in-vivo, preclinical activity in both types of GBM models.
No new drugs for GBM have been approved in over two decades. Lantern Pharma is advancing LP-184, a molecule which demonstrates synthetic lethality when combined with agents that cause DNA damage repair deficiency.2 Additionally, LP-184 has shown that it causes double-stranded breaks in the DNA of recurrent GBM (rGBM) cancer cells in multiple in-vivo models and is currently being advanced in early clinical stage studies.
“Receiving FDA Fast Track Designation for Lantern Pharma’s LP-184 in GBM reinforces our belief that this drug-candidate can help in the critical need to find effective treatment options for patients with GBM and further supports the potential of LP-184 to address the challenges in aggressive CNS cancers, where patients have a critical need for novel and life extending therapies” said Panna Sharma, President and CEO of Lantern Pharma.
Current status of LP-184 & STAR-001 in clinical trials & development
LP-184 is currently being studied in a phase 1A clinical trial to evaluate the safety, tolerability and maximum tolerated dose (MTD) of the potential therapy in a wide range of tumors, including GBM. The full study design can be viewed here (clinicaltrials.gov). Once the MTD has been established, Lantern has plans to advance the drug-candidate LP-184 as STAR-001 through its wholly owned subsidiary, Starlight Therapeutics, in GBM and other CNS and brain cancers.
Lantern also anticipates further using RADR® to determine potential additional suitability for LP-184 in combination with other approved agents for the control of cancer progression in multiple other patient subgroups. Lantern has provided information on the development of LP-184 in GBM and has also discussed its plan to advance STAR-001 (LP-184 for CNS cancers) in multiple publicly available webinars, including on:
- June 26, 2024 — STAR-001 in Multiple Brain and CNS Cancers with Dr. Marc Chamberlain, and
- July 31, 2024 — Born from AI, Lighting The Way in CNS Cancer Treatment with Mr. Panna Sharma.
The proposed goals for the development of Phase 1b/2a clinical studies are targeting a rGBM specific trial to begin in late 2024 or early 2025. This trial is being planned to assess LP-184 in a Phase 1b/2a study as mono-therapy and in combination with spironolactone in rGBM to assess safety, pharmacokinetics and preliminary efficacy. Concurrently, Lantern will conduct a retrospective correlative analysis of multiple key markers of DNA damage as exploratory endpoints. EGFR expression or mutation status, MGMT status and expression of DNA damage repair pathway are also planned to be studied as potential response predictors to help inform and guide future late-stage trials and to stratify enrollment.
About the FDA Fast Track process
The FDA’s Fast Track process is designed to facilitate development and expedite the review of therapies intended to treat serious conditions and address unmet medical needs to potentially bring important new medicines to patients sooner. Companies whose programs are granted Fast Track Designation are eligible for more frequent interactions with the FDA during clinical development. For more information on Fast Track designation, please visit the FDA’s website at www.fda.gov/patients/fast-track-breakthrough-therapy-accelerated-approval-priority-review/fast-track.
About Lantern Pharma:
Lantern Pharma (NASDAQ: LTRN) is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 100 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies that span multiple cancer indications, including both solid tumors and blood cancers and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0 - 2.5 million per program.
Our lead development programs include a Phase 2 clinical program and multiple Phase 1 clinical trials. We have also established a wholly-owned subsidiary, Starlight Therapeutics, to focus exclusively on the clinical execution of our promising therapies for CNS and brain cancers, many of which have no effective treatment options. Our AI-driven pipeline of innovative product candidates is estimated to have a combined annual market potential of over $15 billion USD and have the potential to provide life-changing therapies to hundreds of thousands of cancer patients across the world.
Please find more information at:
- Website: www.lanternpharma.com
- LinkedIn: https://www.linkedin.com/company/lanternpharma/
- X: @lanternpharma
Forward-looking Statements:
This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements include, among other things, statements relating to: future events or our future financial performance; the potential advantages of our RADR® platform in identifying drug candidates and patient populations that are likely to respond to a drug candidate; our strategic plans to advance the development of our drug candidates and antibody drug conjugate (ADC) development program; estimates regarding the development timing for our drug candidates and ADC development program; expectations and estimates regarding clinical trial timing and patient enrollment; our research and development efforts of our internal drug discovery programs and the utilization of our RADR® platform to streamline the drug development process; our intention to leverage artificial intelligence, machine learning and genomic data to streamline and transform the pace, risk and cost of oncology drug discovery and development and to identify patient populations that would likely respond to a drug candidate; estimates regarding patient populations, potential markets and potential market sizes; sales estimates for our drug candidates and our plans to discover and develop drug candidates and to maximize their commercial potential by advancing such drug candidates ourselves or in collaboration with others. Any statements that are not statements of historical fact (including, without limitation, statements that use words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “model,” “objective,” “aim,” “upcoming,” “should,” “will,” “would,” or the negative of these words or other similar expressions) should be considered forward-looking statements. There are a number of important factors that could cause our actual results to differ materially from those indicated by the forward-looking statements, such as (i) the risk that our research and the research of our collaborators may not be successful, (ii) the risk that observations in preclinical studies and early or preliminary observations in clinical studies do not ensure that later observations, studies and development will be consistent or successful, (iii) the risk that we may not be successful in licensing potential candidates or in completing potential partnerships and collaborations, (iv) the risk that none of our product candidates has received FDA marketing approval, and we may not be able to successfully initiate, conduct, or conclude clinical testing for or obtain marketing approval for our product candidates, (v) the risk that no drug product based on our proprietary RADR® AI platform has received FDA marketing approval or otherwise been incorporated into a commercial product, and (vi) those other factors set forth in the Risk Factors section in our Annual Report on Form 10-K for the year ended December 31, 2023, filed with the Securities and Exchange Commission on March 18, 2024. You may access our Annual Report on Form 10-K for the year ended December 31, 2023 under the investor SEC filings tab of our website at www.lanternpharma.com or on the SEC’s website at www.sec.gov. Given these risks and uncertainties, we can give no assurances that our forward-looking statements will prove to be accurate, or that any other results or events projected or contemplated by our forward-looking statements will in fact occur, and we caution investors not to place undue reliance on these statements. All forward-looking statements in this press release represent our judgment as of the date hereof, and, except as otherwise required by law, we disclaim any obligation to update any forward-looking statements to conform the statement to actual results or changes in our expectations.
1 In patients with glioblastoma (GBM) an aggressive and severe type of brain tumor, the cancer medicine temozolomide is more effective in those with a methylation of the gene’s promoter. Overall, MGMT methylation or hyper-methylation is associated with prolonged patient survival in clinical prediction models, while under-methylation or no-methylation can be derived as a result of exposure to temozolomide and cause resistance to temozolomide therapy and therefore no benefit from the use of temozolomide in GBM.
2 Bachchu Lal, Aditya Kulkarni, Joseph McDermott, Rana Rais, Jesse Alt, Ying Wu, Hernando Lopez-Bertoni, Sophie Sall, Umesh Kathad, Jianli Zhou, Barbara S. Slusher, Kishor Bhatia, John Laterra; Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma. Clin Cancer Res 15 October 2023; 29 (20): 4209 4218. https://doi.org/10.1158/1078-0432.CCR-23-0673
Contacts
Investor Relations
mailto: ir@lanternpharma.com
ph: (972) 277-1136 | https://www.biospace.com/fda/lantern-pharmas-investigational-drug-candidate-lp-184-receives-fast-track-designation-in-glioblastoma-from-the-fda | 2024-10-15T17:56:25Z |
New York Jets owner Woody Johnson said on Tuesday that it's going to be a busy week for the franchise — one that he believes will turn a rough start into a winning season.
Speaking to reporters at the NFL owner's meetings, Johnson said "we want to bring a lot of change this week" as news traveled that the team was reportedly acquiring wide receiver Davante Adams from the Las Vegas Raiders — a move the Jets owner couldn't confirm, but said was "in the hopper."
The Jets fell to 2-4 following Monday night's 23-20 overtime loss to the Buffalo Bills, their third straight defeat. Last week's loss to the Minnesota Vikings led to head coach Robert Saleh getting fired. Now they're bringing in an All-Pro wideout and former teammate of quarterback Aaron Rodgers to begin the turn around process.
It's a reversal that Johnson is confident will happen starting with these two big moves in a week.
"Salvageable?," Johnson said of the Jets' season. "We're gonna kick ... you can add the words after that. We're going to do really well."
There are still 11 games to play for the Jets and they are only two games behind the Bills for the AFC East lead. But there's still work to do.
Through six weeks, the Jets are tied for the seventh-most sacks allowed (16), third-most interceptions (5), ninth-worst completion percentage (62.2), are fourth in total receiver drops (11), and own the worst field goal completion percentage (66.7) in the NFL.
What's done is done, Johnson believes. The only thing left to do now is look towards the future — moving Haason Reddick may be next — in order to improve their circumstances.
"You have to look forward," Johnson said. "We have to look forward to the games we're going to play each and every week and try to win all of them and that's basic stuff, right? ... You just have to go with your instinct and what's the best thing to build a team and build a winning team and most importantly build a culture, a culture of winning. And I think based on what I saw yesterday, I think we're starting a new and more exciting direction." | https://www.wftv.com/news/national/jets-owner-woody/LTEP6CRNJNBQI4ZQW5ZVT6O5KM/ | 2024-10-15T17:56:25Z |
ETFs across various categories pulled in $19.5 billion in capital last week. International equity ETFs led the way with $8.6 billion in inflows, followed by inflows of $4.7 billion in U.S. equity ETFs and $2.4 billion in fixed-income ETFs. Notably, China ETFs registered strong inflows.
iShares China Large-Cap ETF FXI, Vanguard S&P 500 ETF VOO, Schwab U.S. Large-Cap ETF SCHX, iShares Core S&P 500 ETF IVV and Xtrackers Harvest CSI 300 China A-Shares ETF ASHR dominated the top creation list last week.
The three main bourses wrapped up the week on a positive note, with the Dow Jones and S&P 500 touching new records. In fact, the S&P 500 Index topped 5,800 for the first time, given the solid start of the third-quarter earnings season with companies issuing bolder forecasts due to the Fed’s rate-cutting cycle. Additionally, the latest inflation report renewed investors’ confidence about easing pricing pressure. Inflation cooled down to 2.4% in September, down from 2.5% recorded in August and in line with market expectations of 2.3%-2.4%. The inflation rate peaked at a 41-year high of 8.9% in June 2022.
Investors continued to pile into China ETFs last week despite a sell-off in Chinese stocks. Mainland China stocks plunged on Oct 9, snapping a 10-day winning streak after confidence in stimulus plans to revive the economy diminished. The blue-chip CSI 300 Index lost 7.1% on Oct 9 while the Shanghai Composite index dropped more than 7%, its worst loss since February 2020 (read: A Few Reasons to Buy China ETFs Now).
We have detailed the ETFs below:
iShares China Large-Cap ETF (FXI)
iShares China Large-Cap ETF topped the asset flow creation last week, gathering $3.5 billion in capital. It offers exposure to large companies in China by tracking the FTSE China 50 Index. It holds 50 stocks in its basket with a slight tilt toward the top three firms. iShares China Large-Cap ETF has key holdings in the consumer discretionary sector with 38.1% share, while financials (27.7%) and communication (16.8%) round off the next two spots.
iShares China Large-Cap ETF has AUM of $10.8 billion and an expense ratio of 0.74%. It trades in an average daily volume of 57 million shares and has a Zacks ETF Rank #5 (Strong Sell) with a Medium risk outlook.
Vanguard S&P 500 ETF (VOO)
Vanguard S&P 500 ETF has gathered $2.5 billion in capital. It tracks the S&P 500 Index and holds 506 stocks in its basket, each accounting for no more than 7.2% of the assets. Vanguard S&P 500 ETF is heavy on the information technology sector, while financials and healthcare round off the next two spots with a double-digit allocation each (read: S&P 500's Best Nine-Month Since 1997: Winning ETFs & Stocks).
Vanguard S&P 500 ETF charges investors 3 bps in annual fees and trades in an average daily volume of 4 million shares. It has AUM of $535.3 billion and a Zacks ETF Rank #1 (Strong Buy) with a Medium risk outlook.
Schwab U.S. Large-Cap ETF (SCHX)
Schwab U.S. Large-Cap ETF has pulled in $2.3 billion in capital. It tracks the Dow Jones U.S. Large-Cap Total Stock Market Index, charging investors 3 bps in fees per year. Schwab U.S. Large-Cap ETF holds 755 stocks in its basket, with none making up for more than 6.7% share. Information technology takes the top spot at 31.9% of assets, while financials and healthcare round off the next spots with double-digit exposure each.
Schwab U.S. Large-Cap ETF has AUM of $49.4 billion and volume is solid at 2.1 million shares on average per day. It has a Zacks ETF Rank #3 (Hold).
iShares Core S&P 500 ETF (IVV)
iShares Core S&P 500 ETF gathered $2.1 billion in capital. It tracks the S&P 500 Index and holds 503 stocks in its basket, each accounting for no more than 7.1% of the assets. iShares Core S&P 500 ETF is heavy on the information technology sector, while financials and healthcare round off the next two spots with a double-digit allocation each.
iShares Core S&P 500 ETF charges investors 3 bps in annual fees. It has an AUM of $540.4 billion and trades in an average daily volume of 3.3 million shares. IVV has a Zacks ETF Rank #1 with a Medium risk outlook (read: 5 Top-Ranked ETFs Beating the S&P 500 in 2024).
Xtrackers Harvest CSI 300 China A-Shares ETF (ASHR)
Xtrackers Harvest CSI 300 China A-Shares ETF saw inflows of $1.5 billion. It tracks the CSI 300 Index and holds 287 securities in its basket, with none making up for more than 4.9%. Xtrackers Harvest CSI 300 China A-Shares ETF has key holdings in financials, industrials, information technology and consumer staples.
Xtrackers Harvest CSI 300 China A-Shares ETF has amassed $3.5 billion in its asset base and charges 65 bps in annual fees from investors. It trades in an average daily volume of 9.1 million shares and currently has a Zacks ETF Rank #5.
Want key ETF info delivered straight to your inbox?
Zacks’ free Fund Newsletter will brief you on top news and analysis, as well as top-performing ETFs, each week.
iShares China Large-Cap ETF (FXI): ETF Research Reports
Vanguard S&P 500 ETF (VOO): ETF Research Reports
Xtrackers Harvest CSI 300 China A-Shares ETF (ASHR): ETF Research Reports
iShares Core S&P 500 ETF (IVV): ETF Research Reports
Schwab U.S. Large-Cap ETF (SCHX): ETF Research Reports
To read this article on Zacks.com click here.
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. | https://www.nasdaq.com/articles/5-etfs-gained-investors-love-last-week-2 | 2024-10-15T17:56:26Z |
Jerry Jones celebrated his 82nd birthday on Sunday by watching his Dallas Cowboys get dismantled by the Detroit Lions 47-9. Two days later, he directed his frustrations towards a pair of hosts on the team's flagship radio station.
Following an offseason that saw the Cowboys spend little on free agents and save big money spending on their own star players —CeeDee Lamb and Dak Prescott — Jones did not take fondly to being asked why he wasn't more active on improving the roster.
Jones' annoyance with the line of questioning had him appearing to threaten the jobs of 105.3 FM's Shan Shariff, R.J. Choppy and Bobby Belt.
This is not your job. Your job isn't to let me go over all the reasons that I did something and I'm sorry that I did it," Jones said. That's not your job. I'll get somebody else to ask these questions. I'm not kidding. You're not going to figure out what the team is doing right or wrong. If you are, or any five or 10 like you, you need to come to this [NFL owner's] meeting I'm going to today with 32 teams here, you're geniuses.
"Ya'll really think you're gonna sit here with a microphone and tell me all of the things that I've done wrong without going all over the rights? Listen, we both know we're talking to a lot of great fans and a lot of great listeners. And I'm very sorry for what happened out there Sunday. I'm sick about what happened Sunday.
"One of the stupidest things I've ever done, that anybody had ever analyzed is buy the Cowboys. It was an idiot that did that. So idiot things can turn into good decisions. Smart things can turn into bad decisions. The facts are that when you make one, you don't really know if it's going to be good or not at the time. You want some conversation this morning, you're getting it."
The Cowboys have their bye in Week 7 before returning to face the San Francisco 49ers on Sunday night in Week 8. There was already going to be a heavy discussion about the construction of Dallas' roster considering their mediocre start and that the NFL's highest-paid quarterback is tied for second in interceptions (6), has an 85.4% passer rating and has been sacked the fifth-most times (16) — not to mention they've lost four consecutive games at AT&T Stadium.
And now the Cowboys will gobble up headlines during an off week — which makes you think Jones knew what he was doing here. He's always been a salesman.
Jones said after Sunday's loss he was happy the bye week was coming as it will give them time to fix the numerous areas that need improvement. Micah Parsons and DeMarcus Lawrence will likely remain out through the bye, further hobbling a 25th-ranked defense that has given up the sixth-most rushing yards and allowed the third-most points through six weeks.
As for change? That's not coming for any part of the Cowboys' roster. Head coach Mike McCarthy's job is safe as Jones reiterated Tuesday by saying in-season coaching changes are "usually ineffective. They just aren't good."
On the field, Jones trusts in his players — his "outstanding personnel" as he put it — to turn around an uninspired start to the season.
"Well, first of all, where you going to go to get any players? Seriously? Where are you going to go to get any players for next week against San Francisco?" Jones said. "Now, No. 1, I've seen these players. I've seen every single one of them execute like you want the plays to be executed and do their job within the role. That didn't happen the other day, and we paid the consequences for it. But I've seen the players do it." | https://www.hits973.com/news/national/jerry-jones-objects/3XSYJLAHP76APG3MMXDXOVXLMM/ | 2024-10-15T17:56:26Z |
Seeking Forever Homes
Meet Bono aka “collar #3540!” This handsome guy is a 3-year-old Irish wolfhound mix. At about 40 pounds, he is a small but mighty version of the breed! When Bono first came to the shelter he was pretty reserved, but he has blossomed into a fun and loving boy. Bono enjoys playing, going on walks, and being close to the people he loves most. Anybody would be lucky to call him their best friend.
Meet Charlotte aka “collar #3548!” This pretty one-year-old lady has a very distinct marking on her nose that we call her spider bite! Charlotte is a very calm and relaxed girl who would love to spend her days snuggled on the couch next to her mom or dad. In her free time, she enjoys sleeping, cuddling, and exploring her surroundings. Charlotte is quite the catch.
Visit Bono, Charlotte, and the other animals at the Lakewood Animal Shelter located at 1299 Metropark Drive, just past the Dog Park. Contact the shelter at (216) 529-5020.
Lakewood Animal Shelter hours: 10:00 a.m. to 4:00 p.m. Monday through Saturday, closed on Sundays.
This message is shared by the Citizens Committee for Lakewood’s Animals and Shelter (CCLAS). CCLAS is an all-volunteer nonprofit organization committed to safeguarding and enhancing the lives of Lakewood’s companion animals. We provide financial assistance and other resources to the Lakewood Animal Shelter for the quality care of abandoned, orphaned, sick, and injured animals. In addition, we promote adoptions and advocate for animal welfare through community outreach and education. We treat animals with empathy, kindness, and respect and recognize that they can experience pain, suffering, and other emotions. Learn more at cclas.org. | https://lakewoodobserver.com/read/2024/10/15/seeking-forever-homes | 2024-10-15T17:56:29Z |
MICHEL MARTIN, HOST:
It is Friday, and that means it's time for StoryCorps. For nearly half a century, a group in Charlottesville, Virginia, has been organizing people to tackle the ultimate challenge, world peace, a fact made all the more remarkable since those people are kids.
(SOUNDBITE OF ARCHIVED RECORDING)
JULIANNE SWOPE: Sometimes World Peace Game feels like, you know, the weight of the world on your shoulders. This is exploding over here, this is firing over there, this is spilling oil. And I say to myself, oh, my gosh, I need to fix this.
MARTIN: The World Peace Game was invented in 1978 by a public school teacher named John Hunter. Students are divided into made-up countries and given a specific role, like prime minister or secretary of the United Nations. They tackle pressing world problems like war and climate change. Hunter retired in 2014. He sat down recently with one of his former students, Irene Newman, to remember an unexpected invitation he and his fourth graders received.
JOHN HUNTER: I get a phone call. Hello, Mr. Hunter? Pentagon. I'd like to know if you could bring your students to the Pentagon so we could ask them directly how they do what they did. And I thought, OK, this is going to be a nice photo op. We're going to have pizza with the general or something like that. No. They brought my (laughter) 24 students in this room, who got very dressed up, by the way - suits and ties for the little guys. One of my girls had her nice, poofy skirt with sparkles and rhinestones on it and sparkly shoes.
IRENE NEWMAN: (Laughter).
HUNTER: And they had their top-secret dossiers under their arms that said in big letters, top secret dossier. And they grilled my students for 3 hours. I remember General Santee, general in the Air Force, bending down to ask my secretary-general of the United Nations, in her poofy skirt, what do you do when you have a supply chain break down? And Sarah, she smoothed her skirt, said, well, I just had to deal with that last week, as a matter of fact.
NEWMAN: (Laughter).
HUNTER: And let me tell you what I did. It was surreal. I'm a teacher of these children, 4 feet tall, peer to peer, nose to nose with some of the most powerful military people in the world, who are taking them seriously. But then before we leave, a door opens in the conference room, and a colonel steps out. He says, Mr. Tuner, we're ready for your delegation. We go in, and there is Leon Panetta, the secretary of defense. He says, I got 10 minutes. I got to go see the president. He says what's your toughest problem? He's serious. And in one voice they all say, well, climate change, of course, because it's affecting everything. He says, you know what, what did you do about it? And they talk for 25, 30 minutes.
He was late to go see the president. The most powerful military commander in the world shows respect to fourth graders who've lived through - sure, in a fictional way - what he's living through every day, and they came asking my students' advice. This is why I'm the most optimistic person you will ever meet, because I've seen children, for almost five decades, figure this out so much so that world leaders have come asking, can your children show us how they do this? Because we've not figured it out. I don't know if it made a difference, whether it changed any of their minds or thinking or not. I don't know. But the fact that it happened at all means an awful lot.
(SOUNDBITE OF MUSIC)
MARTIN: John Hunter speaking with Irene Newman for StoryCorps. John has taught the World Peace Game to children and teachers all over the world. Transcript provided by NPR, Copyright NPR.
NPR transcripts are created on a rush deadline by an NPR contractor. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record. | https://www.ideastream.org/2024-10-11/a-teacher-recalls-when-his-students-schooled-the-pentagon | 2024-10-15T17:56:29Z |
(MENAFN- PR Newswire)
Rising DevSecOps and AI software solution provider discards off-the-shelf system and invests in Unanet to optimize business operations
DULLES, Va., Oct. 15, 2024 /PRNewswire/ -- Unanet, the leading provider of project-based enterprise resource planning (ERP) and customer relationship management (CRM)
for the government contracting (GovCon) industry, today announced that Zaden Technologies (Zaden) has selected Unanet ERP GovCon to grow strategically.
Zaden provides software automation solutions in areas such as development, security and operations
(DevSecOps), cloud computing, and cybersecurity. The company leverages artificial learning to reduce costs and enhance digital transformation for customers in the defense, commercial, health care and aerospace sectors. Zaden's newest software product is an artificial intelligence (AI)-enabled model-based systems engineering tool called Icarus, that quickly modernizes legacy systems for government enterprises. It is attracting interest from capital investors and bringing multiple new business opportunities into the company's pipeline.
As compelling as those opportunities are, leaders at Zaden recognized that to capitalize on these benefits, the company must upgrade its systems, starting with its off-the-shelf financial and accounting software. This software required cumbersome workarounds, costly plug-ins, and lacked the sophistication to scale with their ambitious growth goals.
After formally assessing multiple ERP solutions during a rigorous and thorough
evaluation process, Zaden landed with Unanet, primarily due to Unanet's proven ability to deliver a purpose-built solution that government clients trust to enable defense contract audit agency (DCAA) compliance and the system's streamlined integration with timekeeping, accounting, and payroll.
"Government clients know that Unanet ERP GovCon is built from the foundation with strong DCAA-compliance controls," said Valentine Nwachukwu, president and CEO of Zaden. "As a GovCon startup, indicating that we're using Unanet will demonstrate our maturity in financial management, instill confidence that our firm is DCAA compliant, and support our efforts in bidding on prime government contracts."
Approved business systems are becoming a major differentiator in bids, according to Unanet's most recent GAUGE Report , a widely referenced benchmarking analysis that highlights trends, best practices, and business challenges for GovCons. The findings from this year's edition highlight the growing significance of business systems as an indicator of compliant, high-quality service delivery-and a key competitive differentiator for GovCons when they bid on new business.
Today, more than 2,000 GovCons have selected Unanet ERP GovCon and Unanet CRM because the solutions have the right mix of functionality and accessibility while also offering the ability to scale and grow seamlessly.
To learn more about Unanet solutions for GovCons, please visit .
About Unanet
Unanet is a leading provider of project-based ERP and CRM solutions purpose-built for government contractors, architecture, engineering, construction, and professional services. More than 4,000 project-driven organizations depend on Unanet to turn their information into actionable insights, drive better decision-making, maintain regulatory compliance, and accelerate business growth. All backed by a people-centered team invested in the success of your projects, people, and financials.
For more information, visit
.
About Zaden Technologies
Zaden Technologies offers distinctive DevSecOps, cloud computing, and AI solutions that boost defense system security, scalability, and efficiency. Zaden's Olympus software infrastructure enables rapid deployment of configurable cloud environments with integrated DevSecOps best practices.
Augmenting these capabilities, Zaden leverages cutting-edge artificial intelligence like deep learning and anomaly detection to enable intelligent predictive analytics and automation for enhanced cybersecurity threat visibility and response. Whether modernizing legacy systems or developing new capabilities, Zaden's specialized skill set empowers defense teams to achieve improved speed, quality, and security through their solutions. For more information, visit .
SOURCE Unanet
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currently sitting in the relegation zone with just three points from seven matches.
This surprising position hasn’t been seen at Selhurst Park since March 2018.
Despite the rocky start, there is optimism within the club for a turnaround, especially with upcoming fixtures against Nottingham Forest and Tottenham Hotspur.
Palace’s confidence is buoyed by their strong finish last season, where they clinched six wins from their final seven games, matching their highest-ever points tally of 49 and equalling their best 10th-place finish under Oliver Glasner.
This performance also marked their highest-ever season goal tally with 57, suggesting a return to form is well within reach.
Players’ departure and a new system
Odds courtesy of BetWinner. Correct at time of publishing and subject to change.
The statistics clearly highlight Crystal Palace's struggles.
They hold the league's lowest tally for open-play goals—a solitary one—despite accumulating a respectable xG (expected goals) of 9.44.
Palace rank tenth in the league with 92 shots on goal, but their attack has largely relied on long-range efforts (37, the fourth-highest in the Premier League) and set pieces, the latter accounting for two out of their five goals. Defensively, aerial duels have been a significant pain point.
Losing 137 aerial contests—the most in England’s top flight—highlights a weakness against cross-heavy teams. Moreover, Palace's susceptibility to through balls has been frequently exploited, with opponents threading 18 such passes through their backline, ranking them fourth in this metric behind Brighton, West Ham, and Ipswich Town.
The departures of Michael Olise to Bayern Munich and Joachim Andersen to Fulham significantly altered the squad's dynamic. Their losses meant Glasner not only had to implement a new 3-4-3 formation, but also fill the void left by these pivotal players.
While the club acted quickly in the transfer window by bringing in Maxence Lacroix from Wolfsburg and Trevoh Chalobah on loan from Chelsea, defensive resilience takes time to forge.
However, it’s in the wing-back positions, critical in Glasner’s system, that Palace are lacking alternatives, with only Daniel Muñoz and Tyrick Mitchell capable of fulfilling these demanding roles.
This shortage became painfully obvious when Muñoz suffered an injury early against Liverpool, thrusting Nathaniel Clyne into unfamiliar territory.
Mateta’s return could be the spark
However, these statistics reveal room for improvement.
As adjustments are made and new players integrate into the system, these defensive issues could gradually resolve.
Glasner's history of taking time to apply his methods gives hope that improvement is coming.
He did not win any of his first six games in charge of Crystal Palace last season. Similarly, during his first season with Eintracht Frankfurt in the 2021-2022 campaign, the team was close to the relegation zone in November, managing to win only one league game during the early months—against Bayern Munich at the Allianz Arena.
For the first time in 21 years, they accomplished it after 16 matches.
Between November and December, Frankfurt won six out of seven, ultimately sitting sixth at the end of the first round of matches.
Eberechi Eze shoulders the creative responsibility following Michael Olise's departure to Bayern Munich and remains a shining light.
Despite early challenges, Eze's ability to generate shots—27 attempts (3.9 per game) ranking him third in the league—is a testament to his offensive quality.
Despite underperforming his expected goals (xG) tally, the numbers suggest an upward trajectory, especially considering Jean-Philippe Mateta's expected return to full fitness following an overstretched post-Olympics season.
Positive news regarding Cheick Doucouré's return post-international break could further stabilise the side.
Glasner's openness to tactical flexibility may lead to adjustments in formations that capitalise on players’ strengths.
The option of shifting to a back four or incorporating Ismaïla Sarr's pace could introduce much-needed dynamism ahead of Monday’s game away at Nottingham Forest.
In terms of xPTS (expected points), Palace trail Forest by less than two points, presenting a good opportunity to back the team from South London.
Forest are winless in seven games at the City Ground in all competitions, and their defensive metrics—recording the fewest high turnovers and their high PPDA (passes per defensive action)—indicate a side that may struggle with pressure. Palace haven’t beaten the team from the Midlands since 1991 (six draws, four defeats), but could pose a threat with quick transitions. | https://www.goal.com/en-za/betting/stats-suggest-winless-crystal-palace-are-about-to-turn-the-tide/blt2b3ffbe679d39a90 | 2024-10-15T17:56:31Z |
Use of fake IDs at casinos up 23% in 2024
2024 Casino ID Fraud Special Report outlines trends, risks for casinos and gaming businesses as they combat the use of fraudulent IDs.
The rise in use of fake IDs shows that casinos have a growing risk associated with serving underage patrons.”
NEW ORLEANS, LA, UNITED STATES, October 15, 2024 /EINPresswire.com/ -- After analyzing more than 9,000,000 IDs verified on behalf of casino partners, AI-powered identity tech company IDScan.net has published findings from their 2024 Casino ID Fraud Special Report. — Laurel Morley, Director of Gaming Business, IDScan.net
The report comes after several casinos received six-figure fines for allowing underage gambling and failing to catch fake IDs. Casinos in Virginia, Pennsylvania, and New Jersey were among those who had public incidents in the past twelve months, with several casinos racking up multiple offenses.
Casinos around the country use IDScan.net’s VeriScan age verification and visitor management system to verify IDs and ensure guests are of legal age while drinking or gambling on-site. Some casinos, such as Las Vegas Circa, verify age at the door to maintain an adults-only property, while others spot-check on the casino floor, or verify only at the cage at the time of cash out. IDScan.net has reviewed anonymized results showing the past twelve months of ID verifications on both products across the company’s casino and gaming customer base to reveal new insights into ID fraud trends specific to the industry.
Casinos see an average of 162 fake IDs presented every month, up from 128 in 2023. The majority of these IDs show an age between 21 and 30, with 44% being between 21 and 25, likely indicating that a large percentage of fake IDs presented at casinos is to circumvent age restrictions that do not allow anyone under 21 to gamble. Additionally, 59% of fake IDs presented to casinos are by males - more than 12% higher than at other age restricted businesses such as bars, nightclubs, or alcohol retailers. This indicates that young men are a demographic that is particularly keen to gain entry to casinos using fraudulent identity documents.
“Casinos use ID verification for a number of purposes, but age verification is chief among them,” said IDScan.net Director of Casino & Gaming, Laurel Morley. “The rise in use of fake IDs shows that casinos have a growing risk associated with serving underage patrons.”
Other key findings include the riskiest time of year, and time of day for casinos, as well as differing trends for Vegas-based casinos, non-Vegas casinos, and tribal casinos. Unsurprisingly, Vegas casinos see fake IDs from all 50 states, while non-Vegas and tribal casinos are more likely to see fraudulent documents from within the state they operate. Non-Vegas casinos have seen a sharper increase in fake ID usage - 60% growth since 2023.
IDScan.net’s report is available to download here: Casino ID Fraud Report.
About IDScan.net
IDScan.net is the leading AI-powered identity verification platform focusing on age validation and fraud reduction for high compliance industries, performing more than 15M ID and identity-related transactions monthly.
Jillian Kossman
IDScan.net
+1 5048340222
email us here
Legal Disclaimer:
EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above. | https://www.einpresswire.com/article/750779988/use-of-fake-ids-at-casinos-up-23-in-2024 | 2024-10-15T17:56:31Z |
Valencia have had a tough start to the year, and after nine games find themselves mired in the relegation zone with just one win from the opening two months. However one of their key players will be back in action after the international break.
Los Che have been without their captain for the past few months, after Jose Gaya underwent surgery shortly before Euro 2024, tragically missing his second major tournament in a row through injury. The 29-year-old is back in training, and Valencia confirmed he has the green light from the medical staff to return to action.
Gaya could feature against Las Palmas at home on Monday, as Valencia start a gentler run following their tough start. They then have fellow strugglers Getafe and Espanyol either side of a Copa del Rey clash with Parla and a tie at Mestalla with Real Madrid. While Jesus Vazquez is a strong option on the left, Gaya’s defensive quality and balls into the box are key for Ruben Baraja, but his leadership is essential. | https://www.football-espana.net/2024/10/15/valencia-rejoice-as-key-player-returns-to-action | 2024-10-15T17:56:31Z |
The Pittsburgh Steelers are trending toward making a change at quarterback. Veteran Russell Wilson, who signed with the Steelers in March, is finally healthy enough to start taking first-team reps, and will reportedly do just that this week. That sets him up to make his Steelers debut this weekend when they face the New York Jets.
Sources: The #Steelers plan to give Russell Wilson first-team reps in practice this week, putting him in line to make his season debut and start Sunday night against the #Jets.
— Tom Pelissero (@TomPelissero) October 15, 2024
Pittsburgh is 4-2 with Justin Fields. But Wilson’s calf is fully healed and now he gets his shot. pic.twitter.com/vrhgo7LfgO
Wilson, 35, struggled with a calf injury throughout training camp, but appeared to be on the other side of it as the regular season approached. He was named the starting quarterback prior to Week 1 over Justin Fields, but reaggravated that lurking calf injury just days before the Steelers were due to start their season against the Atlanta Falcons.
The Steelers didn't make a formal announcement about their Week 1 starter before inactives were released, but when when they came out 90 minutes before kickoff, Wilson was on the list. Fields would be the starter going forward, and he helped lead the Steelers to a 3-0 start.
Pittsburgh has had just a few hiccups since then and currently sit at 4-2. Despite that strong, Tomlin is definitely putting Wilson in consideration to be the Week 7 starter.
Tomlin: "[Russell Wilson] is in consideration this week. We'll see where that leads us.
— Andrew Siciliano (@AndrewSiciliano) October 15, 2024
The Steelers need an offensive push, and Wilson can definitely give that to them. And Russ wants redemption more than ever after two disastrous years with the Denver Broncos. Now he's closer than ever to proving he's got more passes left in that mighty arm. | https://www.wftv.com/news/national/steelers-qb-russell/MSTXC3ORJOLPTSSXPTSPRH45VE/ | 2024-10-15T17:56:32Z |
New York Jets owner Woody Johnson said on Tuesday that it's going to be a busy week for the franchise — one that he believes will turn a rough start into a winning season.
Speaking to reporters at the NFL owner's meetings, Johnson said "we want to bring a lot of change this week" as news traveled that the team was reportedly acquiring wide receiver Davante Adams from the Las Vegas Raiders — a move the Jets owner couldn't confirm, but said was "in the hopper."
The Jets fell to 2-4 following Monday night's 23-20 overtime loss to the Buffalo Bills, their third straight defeat. Last week's loss to the Minnesota Vikings led to head coach Robert Saleh getting fired. Now they're bringing in an All-Pro wideout and former teammate of quarterback Aaron Rodgers to begin the turn around process.
It's a reversal that Johnson is confident will happen starting with these two big moves in a week.
"Salvageable?," Johnson said of the Jets' season. "We're gonna kick ... you can add the words after that. We're going to do really well."
There are still 11 games to play for the Jets and they are only two games behind the Bills for the AFC East lead. But there's still work to do.
Through six weeks, the Jets are tied for the seventh-most sacks allowed (16), third-most interceptions (5), ninth-worst completion percentage (62.2), are fourth in total receiver drops (11), and own the worst field goal completion percentage (66.7) in the NFL.
What's done is done, Johnson believes. The only thing left to do now is look towards the future — moving Haason Reddick may be next — in order to improve their circumstances.
"You have to look forward," Johnson said. "We have to look forward to the games we're going to play each and every week and try to win all of them and that's basic stuff, right? ... You just have to go with your instinct and what's the best thing to build a team and build a winning team and most importantly build a culture, a culture of winning. And I think based on what I saw yesterday, I think we're starting a new and more exciting direction." | https://www.hits973.com/news/national/jets-owner-woody/LTEP6CRNJNBQI4ZQW5ZVT6O5KM/ | 2024-10-15T17:56:34Z |
CAMBRIDGE, Mass.--(BUSINESS WIRE)--$AMLX--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today announced the Company will host a virtual webcast on October 17, 2024 at 1:30 p.m. ET with management and Fumihiko Urano, MD, PhD, principal investigator of the HELIOS clinical trial and the Samuel E. Schechter Professor of Medicine in the Division of Endocrinology, Metabolism & Lipid Research at Washington University School of Medicine in St. Louis (WashU Medicine), to discuss topline results from HELIOS, a Phase 2 trial of AMX0035 (sodium phenylbutyrate [PB] and taurursodiol [TURSO, also known as ursodoxicoltaurine]) for the investigational treatment of Wolfram syndrome. The live webcast follows the presentation of these data at the International Society for Pediatric and Adolescent Diabetes 50th Annual Congress in Lisbon, Portugal.
The live webcast can be accessed under “Events and Presentations” in the Investor section of the Company’s website, https://investors.amylyx.com/news-events/events, and will be available for replay for 90 days following the event.
Dr. Fumihiko Urano is a physician and leading medical researcher at WashU Medicine in St. Louis specializing in the study of Wolfram syndrome and related disorders, including WFS1-related disorders/Wolfram-like disorders. As director of the Wolfram Syndrome Clinic and the Wolfram Syndrome International Registry & Clinical Study at Washington University, Dr. Urano treats patients and leads basic science, clinical, translational, and interventional studies of Wolfram syndrome and related disorders.
About the HELIOS Trial
The HELIOS trial (NCT05676034) is a 12-participant, open-label, proof of biology, Phase 2 trial designed to study the effect of AMX0035 on safety and tolerability, and various measures of endocrinological, neurological, and ophthalmologic function in adult participants living with Wolfram syndrome.
About Wolfram Syndrome
Wolfram syndrome is an autosomal recessive neurodegenerative disease characterized by childhood-onset diabetes, optic nerve atrophy, and neurodegeneration. Common manifestations of Wolfram syndrome include diabetes mellitus, optic nerve atrophy, central diabetes insipidus, sensorineural deafness, neurogenic bladder, and progressive neurologic difficulties. Genetic and experimental evidence suggests that endoplasmic reticulum (ER) dysfunction is a critical pathogenic component of Wolfram syndrome. The prognosis of Wolfram syndrome is poor, and many people with the disease die prematurely with severe neurological disabilities.
About AMX0035
AMX0035 is an oral, fixed-dose combination of sodium phenylbutyrate (PB) and taurursodiol (TURSO; also known as ursodoxicoltaurine outside of the U.S.). AMX0035 was designed to slow or mitigate neurodegeneration by targeting endoplasmic reticulum (ER) stress and mitochondrial dysfunction, two connected central pathways that lead to cell death and neurodegeneration. We believe that our proprietary combination of PB and TURSO and their complementary mechanisms of action will allow us to synergistically target abnormal cell death to better prevent neurodegeneration than treatment targeted at either mechanism of action alone. AMX0035 is being studied as a potential treatment for Wolfram syndrome and progressive supranuclear palsy, two neurodegenerative diseases.
About Amylyx Pharmaceuticals
Amylyx is committed to the discovery and development of new treatment options for communities with high unmet needs, including people living with serious and fatal diseases. The Company has preclinical or clinical development programs underway in neurodegenerative, neuroendocrine, and endocrine diseases. Since its founding, Amylyx has been guided by science to address unanswered questions, keeping communities at the heart and center of all decisions. Amylyx is headquartered in Cambridge, Massachusetts. For more information, visit amylyx.com and follow us on LinkedIn and X. For investors, please visit investors.amylyx.com.
Contacts
Media
Amylyx Media Team
+1 (857) 799-7274
amylyxmediateam@amylyx.com
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Lindsey Allen
Amylyx Pharmaceuticals, Inc.
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Investors@amylyx.com | https://www.biospace.com/news/amylyx-pharmaceuticals-to-host-virtual-webcast-to-discuss-topline-results-from-phase-2-helios-study-of-amx0035-in-wolfram-syndrome-on-october-17-2024 | 2024-10-15T17:56:35Z |
Vote YES On Issue 1 To End Gerrymandering
Neighbors, I am writing to urge you to vote YES on ISSUE 1.
I came to my service on City Council after years of volunteer community organizing, bringing people together to advocate to their elected officials for needed change. Our power as citizens comes from collective action and our votes. When politicians are able to draw their own districts to favor their own re-election, they take away the power of the people that they are supposed to serve. When politicians draw districts that can only realistically be won by candidates of one particular party, it means that the election is determined by the primary. Since the vast majority of voters are Independent, that means that they do not get a say in who will represent them, and it leads to elected officials who have more extreme positions than their constituents. This practice is called gerrymandering, and it is bad for all Ohioans.
Issue 1, the Citizens Not Politicians Amendment, will take redistricting out of the hands of politicians. It will create the 15-member Ohio Citizens Redistricting Commission made up of Democratic, Republican, and Independent citizens who broadly represent the different geographic areas and demographics of the state. Issue 1 will ban current or former politicians, political party officials and lobbyists from sitting on the Commission. Issue 1 will require fair and impartial districts by making it unconstitutional to draw voting districts that discriminate against or favor any political party or individual politician.
The misinformation campaign around Issue 1 reflects just how scared some politicians are of losing the power of gerrymandering. Four recent events show that when politicians draw their own gerrymandered districts, they completely lose touch with the voters that they're supposed to represent.
1: Extremist politicians held the Aug. 8 special election last year to try to block citizen-led constitutional amendments.
2: Extremist politicians passed one of the most backward and restrictive anti-abortion laws in the country, and the voters amended the constitution to protect reproductive rights.
3. Extremist politicians changed the ballot language of Issue 1 to confuse voters.
4. The current district maps were ruled unconstitutional five times by the Ohio Supreme Court, but extremist politicians disregarded the judges and voters and implemented the maps anyway.
I urge you to read the actual language of Issue 1 at https://www.citizensnotpoliticians.org/petition/ and vote YES on Issue 1 on or before November 5th. You can vote early right now at the Board of Elections or request your vote by mail application.
President Sarah Kepple serves all residents as Lakewood City Councilmember at Large. Reach her at sarah.kepple@lakewoodoh.gov or 216.200.5050.
Sarah Kepple
President Sarah Kepple serves all residents as Lakewood City Councilmember at Large. Reach her at sarah.kepple@lakewoodoh.gov or 216.200.5050. | https://lakewoodobserver.com/read/2024/10/15/vote-yes-on-issue-1-to-end-gerrymandering | 2024-10-15T17:56:35Z |
(MENAFN- PR Newswire)
Combines the Best of Digital and Offline Data with AI to Deliver an Average 8x Incremental Return on Ad Spend
NEW YORK and CHICAGO
, Oct. 15, 2024 /PRNewswire/ --
PebblePost , the creator and leader of the Programmatic Direct Mail (PDM) channel, which combines the best of digital and direct mail advertising, today announced enhancements to its Lookalikes prospecting product. They include:
Best-in-class incremental marketing performance
Always-on capabilities, just like retargeting
Continuous audience optimization
Advanced performance analytics
Fueled by the PebblePost Graph: shared first-party cookieless, online and offline data.
"Customer acquisition at scale that performs is hard to do," said Jacob Ross, PebblePost's CEO. "PebblePost's enhanced Lookalikes product helps brands make it easier and more efficient. Our market-leading product now delivers greater performance and reach for brands to help them grow their customer base faster than they thought possible. Brands leveraging this Lookalikes product see an average 8x return on advertising spend (ROAS), beating our prior version of Lookalikes with 40% higher reach and 30% better conversion rates."
The enhanced Lookalikes product will be a highlight of PebblePost's presence at the Shoptalk Fall conference (Booth #H53, McCormick Place) in Chicago this week.
Best-in-Class Performance Powered by Proprietary Data
PebblePost is the only PDM solution that combines three of the most predictive data types across 500+ brands: transaction, intent, and customer data. This gives PebblePost a more holistic view of a consumer for modeling, which yields higher conversion rates when compared to other solutions that rely on third-party data.
"Blue Nile was already seeing strong success with PebblePost's Lookalikes prospecting product. However, we couldn't be happier with the performance improvements we're seeing with their enhanced Lookalikes, a stunning 70% increase in ROAS," said Megan Birch, Blue Nile's Senior Director of Marketing. "An always-on approach to Lookalikes has allowed us to focus on identifying and engaging our most valuable prospects, and we've been able to scale our monthly investments by up to 6x."
Always-on Capabilities for Continuous Optimization
PebblePost's AI scores nearly 100% of U.S. households daily, using billions of online and offline signals connected to a brand's first-party data. With audience pools that remain fresh and relevant, brands can reach more prospects with active purchase intent faster. Instead of waiting weeks or months for program results, PebblePost's models get smarter continuously with an ongoing feedback loop to optimize in real time.
"As a digital marketer, I can appreciate the difference maker that PebblePost's enhanced Lookalikes represents," said Allie Wooster, BBQGuys' Channel Manager, Programmatic and Affiliates. "It has the efficiency, performance, and always-on characteristics of a lookalike campaign run in a digital channel, with the additional benefit of working seamlessly in direct mail. With lift measurement on every program, PebblePost has instilled confidence that we're exceeding our 10x ROAS benchmark for prospecting."
Backed by Advanced Performance Analytics and Incrementality
"We know that it is not enough to show great performance-although we do-we also have to show why, so brands can fully trust the result," Ross said. "To ensure that PebblePost employs market-leading analytics to help marketers plan, optimize, and measure their always-on marketing programs, including built-in incrementality measurement across all of our products, including the enhanced Lookalikes product."
PebblePost's real-time dashboard lets brands look at performance results in any way a marketer would want–with unmatched data transparency. PebblePost also integrates with leading marketing measurement platforms to enable brands to verify results with trusted third-party partners and against their other marketing efforts.
Built for the Enterprise, By Experts
PebblePost's team acts as strategic partners to brands, focused on unlocking success through a comprehensive, outcomes-based approach.
"As a new brand with ambitious goals, attracting new Sailors (guests) to Virgin Voyages is essential," said Liza Herth, Virgin Voyages' Senior Manager, Lifecycle Marketing. "PebblePost has been instrumental in unlocking the potential of lookalike audiences through their always-on solution. They truly act as an extension of our team, offering comprehensive support-from audience targeting and creative testing recommendations to performance updates and detailed reporting for revenue attribution. With a premium price point and a niche audience, efficiently driving incremental revenue is critical. PebblePost listens closely to our business challenges and collaborates with us on creative solutions, consistently delivering a cost-per-booking that no other acquisition channel can match."
About PebblePost
PebblePost is the industry leader in Programmatic Direct Mail, creating the next generation of addressable marketing. Our solutions enable brands to reach decision-ready consumers across the online and offline moments that matter to drive measurable performance everywhere. The company partners with hundreds of leading brands to power profitable growth by engaging people at home with timely, relevant offers. The shared first-party data managed by PebblePost has enabled brands to realize $1.5 billion incremental revenue YTD and achieve 10x average incremental ROAS for acquisition and 36x average incremental ROAS for retention. Of the brands that work with PebblePost, 85% exceed their KPIs by 4x on average. For more information, please visit
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SOURCE PebblePost
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MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780697/Pebblepost-Announces-Enhanced-Lookalikes-Product-Brings-Higher-Performance-With-Categorys-First-Always-On-Prospecting-Solution | 2024-10-15T17:56:36Z |
Victoria Roshchyna, a Ukrainian journalist held captive by Russia for more than a year, died while in Russian detention, Ukrainian officials confirmed Thursday.
Petro Yatsenko, a spokesperson for Ukraine’s Prisoners of War Coordination Headquarters, told Ukrainian television that the circumstances surrounding Roshchyna’s death were still unclear.
“It is too early to talk about the circumstances of the death, we are working to establish them,” Yatsenko said.
According to a statement from the press freedom watchdog Reporters Without Borders, or RSF, Roshchyna’s family received a letter on Thursday from Russia’s Defense Ministry informing them that she died on Sept. 19.
Roshchyna, who would have turned 28 this month, was one of 20 Ukrainian journalists detained by Russia for their reporting since the start of Russia’s invasion on Feb. 24, 2022, according to RSF.
She was known for her features documenting daily life in Russian-occupied eastern Ukraine, went missing on Aug. 3, 2023, while traveling on assignment to the Russian-occupied town of Zaporizhzhia, according to the International Women's Media Foundation. Her whereabouts were unknown for eight months until Russia’s Defense Ministry confirmed her detention in April 2024.
“The Russian authorities have never provided any information about her detention, despite repeated requests from her family, the Ukrainian authorities, and RSF,” said Jeanne Cavelier, the head of RSF’s Eastern Europe and Central Asia Desk. She added: [Russia] must shed light on all the circumstances surrounding her detention and death. Our thoughts and support go out to her loved ones.”
On social media, friends and colleagues expressed shock, with some also demanding more answers from Russia about Roshchyna’s death.
“I have a question. What did they do with her? What could have been done to a young girl to make her die?” Oleksandra Matviichuk, the head of the nonprofit Center for Civil Liberties Ukraine wrote on X. “I call on all journalistic organizations from different countries to officially demand an answer from Russia.”
Nataliya Gumenyuk, a Ukrainian journalist and former colleague of Roshchyna's, remembered her as "the bravest, the most determined, adding "she risked to tell the truth about occupation."
According to the independent Russian news outlet Mediazona, Roshchyna died while she was in the process of being transferred from a prison in Taganrog, near the Ukrainian border, to Moscow.
Roshchyna was the winner of the 2022 Courage in Journalism award from the International Women's Media Foundation, or IWMF. In a statement, the IWMF said it was "devastated" to learn of Roshchyna's death.
"Victoria’s passing is not just the loss of a remarkable woman, but of an intrepid witness to history. Regardless of her cause of death, we can say with certainty that her life was taken because she dared tell the truth. We hope her death will not be in vain: the international community must pressure Russia to cease targeting journalists and silencing press freedom."
Copyright 2024 NPR | https://www.ideastream.org/2024-10-11/award-winning-ukrainian-journalist-dies-in-russian-captivity-kyiv-says | 2024-10-15T17:56:36Z |
The Blues have picked up 14 points from their last six Premier League outings, after losing their opener against Manchester City. Maintaining that pace is now a challenge for Chelsea as they aim to qualify for the Champions League this season.
Chelsea’s impressive 4-2 win over Brighton at the end of last month made everyone, including the bookmakers, stand up and take notice. However, we assess whether or not now is the time to back against Maresca’s side as they gear up to face Liverpool.
Chelsea Face a Tricky Run of Fixtures
Odds courtesy of Betway. Correct at time of publishing and subject to change.
Chelsea have undoubtedly improved on last season. They have netted an average of 2.29 goals per game, with only Manchester City scoring more in the top tier of English football; however, their poor defence has contributed to their struggles.
Six of the Blues’ goals came against Wolves, who have conceded the most goals in the Premier League, with an average of three per game. Chelsea were also able to take advantage of a West Ham defence that was all at sea last month.
The Hammers’ high line was extremely vulnerable when the team lost possession and Maresca’s team were able to pounce. A week later, Brighton’s defence capitulated as they conceded four first-half goals against the Blues. The opening goal of the game was a gift from Adam Webster, and soon after, Carlos Baleba gave away a penalty.
In their last outing, Chelsea faced a far more resilient Nottingham Forest side at Stamford Bridge. Nuno Espirito Santo’s side had conceded just six goals coming into that clash. Forest went on to secure a 1-1 draw. Only Arsenal and Liverpool have better defensive records at this stage.
Chelsea faces some challenging matches in the weeks ahead. They face both Liverpool and Arsenal, the league’s sturdiest defences, in their next four league games.
The other two matches are against Newcastle and Manchester United. The Blues also have to navigate two Europa Conference League matches, as well as an EFL Cup clash with Eddie Howe’s side during that period.
The Blues Face Firm Liverpool Defence
Liverpool have the best defence in the Premier League this season. They have conceded just two goals across their seven matches, meaning their opponents have scored an average of just 0.29 goals per game. The league leaders will be hoping to keep it tight once again as they look to shut out this Chelsea attack.
Arne Slot has won nine of his first 10 matches in charge of the Reds. Their underlying data in the league also paints a promising picture.
Their xGA of 5.72 is the lowest in the division. Chance creation also hasn’t been a problem. Liverpool have scored an average of 1.86 goals per game and have the third-highest xG in the Premier League.
The Reds have a hugely impressive record in front of their own fans. They have lost three Premier League home games since the start of the 2021/22 campaign, and have conceded an average of just 0.79 goals per game in the process.
Chelsea have won just one of their last nine Premier League matches at Anfield. | https://www.goal.com/en-za/betting/why-now-is-the-time-to-bet-against-chelsea-in-the-premier-league/blt012bd85d3a75b00f | 2024-10-15T17:56:37Z |
(MENAFN- PR Newswire)
NEW YORK and LOS ANGELES, Oct. 15, 2024 /PRNewswire/ -- The tech market in the United States, particularly in San Francisco, is growing at lightning speed rates and simultaneously delivering immaculate business transformations. The San Francisco Bay Area region is already nicknamed the Silicon Valley of the world due to being a global hub due to the huge number of tech, electronics, and computer companies stationed there, and AI development and innovation are a huge part of it. This evolving landscape and change in business dynamics have led enterprises to turn their sights to seeking the expertise of leading AI development companies to curate customized and inventive artificial intelligence solutions. With tech goliaths and startups vying for supremacy, the need for sophisticated, tailored AI solutions persists to grow, propelling intense competition among brands. Custom AI development isn't just a luxury implementation anymore but an indispensable tool in retaining a competitive edge among bigger corporations.
Custom AI development isn't just a luxury implementation anymore but an indispensable tool in retaining a competitive edge among bigger corporations. Organizations across sectors, including entertainment, e-commerce, and healthcare, are utilizing the straightforwardness of artificial intelligence to detect user browsing patterns, enhance consumer involvement, and promote sustained development. This transition has put organizations supplying complete technology and artificial intelligence services in tremendous demand, especially the ones that can supply tailored solutions that satisfy specific company demands. That's where Hyperlink InfoSystem, the leading AI development companies in San Francisco in 2024, realized the enormous potential of AI and ML and promptly invested in it. By collating a team of skilled AI experts and incorporating emerging technologies, their commitment to curating tailored and transformative AI solutions has made them earn this accolade.
Hyperlink InfoSystem, a global leader and recognized as top AI development company by various B2B reviews and ratings platform, provides a comprehensive range of AI development services encompassing natural language processing, AI-driven app development, machine learning, predictive analytics, automation systems, AI chatbot development, and computer vision. By bringing together the best technical expertise and a profound understanding of business demands, the company helps its clients unlock the true power of AI to drive growth and efficiency. Their team's technical prowess goes beyond AI into custom app development, Salesforce CRM implementation, blockchain, IoT, web development, software development, and AR/VR, rendering them an all-in-one tech powerhouse for companies looking to embrace and adapt modern technology. Hyperlink InfoSystem's core values of being passionate about pushing the boundaries of what's possible have solidified its industry position as a reliable partner for custom AI solutions.
"AI development in 2024 is a critical business aspect for many industries and has created unparalleled opportunities to transform operations and drive profitable growth. Thus, being recognized as the leading AI development company in San Francisco in 2024 is nothing less than a delightful honor," said Harnil Oza, CEO of Hyperlink InfoSystem. He also said, "At Hyperlink InfoSystem, we are dedicated to staying at the forefront of artificial intelligence and machine learning technology to supply our clients with solutions that aren't just modern but also suitably aligned with their business goals. This honor is a testament to our team's passion for innovation, incredible expertise, and a lot of hard work."
As Hyperlink InfoSystem strives further to lead the way in AI development, the company aspires to nurture partnerships with industry leaders and render outstanding customer service in San Francisco and beyond. The organization desires to remain committed to assisting businesses to unlock new opportunities for providing bespoke AI solutions. Since its inception in 2011, Hyperlink InfoSystem has held an impressive track record of over 2700 pleased clients and a portfolio of over 4500 applications, 2300 websites, 120 AI & IoT solutions, 140 games, 120 Salesforce solutions, 25 blockchain solutions, 60 data science projects, and 1200 committed professionals. With their forward-thinking approach, they're ready to usher businesses towards transformative digital journeys. Hyperlink InfoSystem is well-positioned to maintain its position as a leading web development firm in San Francisco and worldwide by remaining on top of industry trends and investigating emerging technology. One can email at [email protected]
to learn more about their AI development services.
About Hyperlink InfoSystem
Hyperlink InfoSystem is a prominent international enterprise excelling in IT solutions in many domains. Since its humble beginnings in 2011, its specialization in technologies has expanded across web development, mobile app development, enterprise software solutions, and now Artificial Intelligence (AI). With over 1200+ employees and a global presence in the
USA, UK, UAE,
France,
India, and
Canada, Hyperlink InfoSystem is dedicated to assisting corporations to leverage the complete power of technology to accomplish their goals.
Contact Details:
Hyperlink InfoSystem
Harnil Oza
+1-309-791-4105
[email protected]
New York Address:
One World Trade Center
285 Fulton Street suite 8500,
New York, NY
10007,
United States
Ahmedabad Address:
C-308, Ganesh Meridian,
Opp Kargil Petrol Pump, S.G. Highway,
Sola, Ahmedabad, 380061
India
London Address:
Level 30, The Leadenhall Building,
122 Leadenhall Street,
London
EC3V 4AB
Canada Address:
151
Yonge Street, 11th Floor,
Toronto, Ontario, M5C 2W7,
Canada
Logo: g
SOURCE Hyperlink Infosystem
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DETROIT — (AP) — Kamala Harris and Donald Trump both pushed Tuesday to energize key constituencies that their allies worry might be slipping away, with the vice president looking to reach Black men and the former president focusing on women.
Harris will appear at a town hall-style event in Detroit hosted by the morning radio program “The Breakfast Club," featuring Charlamagne Tha God, who is especially popular with Black males. Trump, meanwhile, will tape a Fox News Channel town hall featuring an all-female audience and moderated by host Harris Faulkner.
The vice president was also scheduled to stop by a Black-owned business in Detroit. A day earlier, she visited LegendErie, a coffee shop and record store in Erie, Pennsylvania, where she met with the husband-and-wife owners, a local pastor and other community leaders.
Harris' running mate, Minnesota Gov. Tim Walz, is unveiling his ticket's plan to improve the lives of rural Americans. It's yet another sign that in a razor-tight race, each side is trying to cut into the other's margins of support with different voting blocs while shoring up traditional areas of strength.
The vice president's "Breakfast Club" appearance comes one day after she announced a series of new proposals dubbed the "Opportunity Agenda for Black Men." The ideas are meant to offer the demographic more economic advantages, including providing forgivable business loans of up to $20,000 for entrepreneurs and creating more apprenticeships. The plan would also support the study of sickle cell and other diseases more common in Black men.
The focus on Black men sharpened last week when former President Barack Obama campaigned for Harris in Pittsburgh and said he wanted to speak "some truths" to Black male voters, suggesting some " just aren't feeling the idea of having a woman as president."
The vice president’s campaign says it doesn’t believe Black men will flip in large numbers to supporting Trump, especially after strongly backing Democrat Joe Biden, with Harris as his running mate, in 2020. They are more concerned about a measurable percentage of Black males opting not to vote at all.
Sen. Raphael Warnock, the first Black senator elected from the state of Georgia, issued a stark warning Tuesday to other Black men that voting for Trump will be “literally dangerous” for them, as the former president heads to Atlanta for a rally.
“He will be dangerous every time you get in the car and you deal with the issue of driving while Black,” Warnock said.
He argued that Democrats’ job is to reach Black men who are deciding whether to vote at all. “The issue is folks have got to understand that if you do not vote, it’s a vote for Donald Trump,” Warnock said.
Harris' campaign has also placed special emphasis on other male voters, including creating " Hombres con Harris," or "Men with Harris," a group that is using celebrities and key elected officials to organize events on her behalf meant to appeal to Hispanic men.
As she campaigns in Detroit, Harris faces other potential challenges in Michigan, including Arab activists angered by the Biden administration's full-throated support for Israel in its war with Hamas in Gaza. Dearborn, outside Detroit, is the largest Arab-majority city in the U.S.
Still, the vice president's campaign expects to see strong support on Election Day from white, college-educated voters in Michigan at rates that might exceed Biden's in 2020, and she hopes to expand the margin by which Trump lost many of the state's key suburbs four years ago.
She's also seized on insults Trump made about Detroit last week while campaigning there. He said if Harris wins, “Our whole country will end up being like Detroit." He added, "You’re going to have a mess on your hands.”
Trump has maligned cities hosting him before, but Harris said it was proof he was “unfit to be president.” Her campaign also released an ad voiced by actor Courtney B. Vance, a Detroit native, that declares: “What Donald Trump doesn’t understand, or care to learn, is that when he said, ‘Our whole country will end up being like Detroit if she’s your president.’ That he should be so ... lucky.”
Trump is scheduled to return to Detroit later this week for a rally.
The former president figures to do well with rural voters, but team Harris hopes to at least keep things closer. And while Harris’ support among women is strong, Trump aims to keep her from running up the score.
Trump has seen his support among women, especially in the suburbs of many key swing states, soften since his term in the White House. A September AP-NORC poll found more than half of registered voters who are women have a somewhat or very favorable view of Harris, while only about one-third have a favorable view of Trump.
To reverse the trend, Trump has sought to cast himself as being able to personally shield women from various threats, as when he suggested at a rally in Pennsylvania last month that women in America, "will no longer be abandoned, lonely or scared. You will no longer be in danger."
“You will be protected, and I will be your protector," Trump said then. He's also suggested that, should he win, women will no longer have a reason to think about abortion, after three Supreme Court judges that he appointed helped in 2022 to overturn the landmark Roe v. Wade decision that had guaranteed a woman's right to the procedure.
In Chicago before members of the Economic Club, Trump defended his support for high tariffs as an economic cure-all.
“To me, the most beautiful word in the dictionary is ‘tariff,’” Trump told Bloomberg Editor-in-Chief John Micklethwait, who interviewed him at the event. Micklethwait has repeatedly pressed Trump on warnings from economists that the costs of high tariffs will be passed along to American consumers, raising prices.
___
Associated Press Writer Bill Barrow in Atlanta and Jill Colvin in Chicago contributed to this report.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/news/politics/harris-zeroes-black/XJ4TUOSEA5BDBP6GUZEUNDPTUQ/ | 2024-10-15T17:56:39Z |
What A Day At Active Aging Week Community Day!
Last Wednesday at Lakewood Park was fantastic! Perfect weather and great energy while celebrating healthy, active aging.
The day was filled with fun activities, including line dancing, adaptive Tai Chi, yoga, Qi Gong, belly dancing, blood pressure screenings, journaling with Dr. Marta, science trivia with Science with Dan, and an energizing drum circle at the Solstice Steps. The Cleveland Road Runners Club even hosted a fun run!
If you missed it, it was a day full of laughter, movement, and connection. Let’s continue working toward healthy, happy aging together! If we keep this up, we might just be aging in reverse! We can't wait to do it again next year!
Nancy Feighan
Nancy Feighan
Project Specialist II, Department of Human Services, City of Lakewood
Volume 20, Issue 20, Posted 12:21 PM, 10.15.2024 | https://lakewoodobserver.com/read/2024/10/15/what-a-day-at-active-aging-week-community-day | 2024-10-15T17:56:41Z |
The Pittsburgh Steelers are trending toward making a change at quarterback. Veteran Russell Wilson, who signed with the Steelers in March, is finally healthy enough to start taking first-team reps, and will reportedly do just that this week. That sets him up to make his Steelers debut this weekend when they face the New York Jets.
Sources: The #Steelers plan to give Russell Wilson first-team reps in practice this week, putting him in line to make his season debut and start Sunday night against the #Jets.
— Tom Pelissero (@TomPelissero) October 15, 2024
Pittsburgh is 4-2 with Justin Fields. But Wilson’s calf is fully healed and now he gets his shot. pic.twitter.com/vrhgo7LfgO
Wilson, 35, struggled with a calf injury throughout training camp, but appeared to be on the other side of it as the regular season approached. He was named the starting quarterback prior to Week 1 over Justin Fields, but reaggravated that lurking calf injury just days before the Steelers were due to start their season against the Atlanta Falcons.
The Steelers didn't make a formal announcement about their Week 1 starter before inactives were released, but when when they came out 90 minutes before kickoff, Wilson was on the list. Fields would be the starter going forward, and he helped lead the Steelers to a 3-0 start.
Pittsburgh has had just a few hiccups since then and currently sit at 4-2. Despite that strong, Tomlin is definitely putting Wilson in consideration to be the Week 7 starter.
Tomlin: "[Russell Wilson] is in consideration this week. We'll see where that leads us.
— Andrew Siciliano (@AndrewSiciliano) October 15, 2024
The Steelers need an offensive push, and Wilson can definitely give that to them. And Russ wants redemption more than ever after two disastrous years with the Denver Broncos. Now he's closer than ever to proving he's got more passes left in that mighty arm. | https://www.hits973.com/news/national/steelers-qb-russell/MSTXC3ORJOLPTSSXPTSPRH45VE/ | 2024-10-15T17:56:41Z |
The billion-pound bottlejobs? Chelsea sporting directors speak out in first major interview since Gary Neville jibe after Carabao Cup final
Chelsea sporting directors Laurence Stewart & Paul Winstanley labelled Gary Neville's "billion-pound bottlejobs" jibe as "outside noise".
Article continues below
Article continues below
Article continues below
- Chelsea lost to Liverpool in 2024 Carabao Cup final
- Neville took a harsh dig at Blues
- Winstanley & Stewart respond to criticism | https://www.goal.com/en-za/lists/billion-pound-bottlejobs-chelsea-sporting-directors-gary-neville-carabao-cup-final/blta2f80dba86cefbb5 | 2024-10-15T17:56:43Z |
(MENAFN- PR Newswire)
Transaction will expand global offering and drive workforce management innovation to meet the future needs of businesses
ROSELAND, N.J., Oct. 15, 2024 /PRNewswire/ --
ADP®
(Nasdaq: ADP ), a leading global technology company providing human capital management (HCM) solutions, today announced that it has acquired WorkForce Software, a premier workforce management solutions provider that specializes in supporting large, global enterprises. This Acquisition will expand ADP's global offering of workforce management solutions and enable future innovation in the space.
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"As the needs of today's global workforce continue to shift, employers need dynamic workforce management solutions that will help them maintain compliance and flexibility while engaging their employees," said Maria Black, president and CEO of ADP.
"We are excited to welcome the WorkForce Software team to ADP and will leverage the deep expertise across both teams to further innovate and address the many unique and wide-ranging needs of our clients."
Transaction will expand global offering and drive workforce management innovation to meet the future needs of businesses
Post this
Founded in 1999 and headquartered in Michigan, WorkForce Software's robust time and attendance, scheduling, forecasting, leave and absence management, and employee communications capabilities, as well as their trusted global support organization, will broaden the full suite of workforce management solutions ADP offers to meet the needs of its more than one million clients in over 140 countries.
WorkForce Software's
solutions adapt to an organization's needs, and can accommodate unique pay rules, labor regulations, and schedules. Whether employees are deskless, hourly, unionized, full-time, part-time, or seasonal, WorkForce Software
has focused on offering tools that create resiliency, drive optimal performance and make managing a global workforce easy.
"The WorkForce Software team is thrilled to join ADP," said Jeff Moses, CEO of WorkForce Software. "For 25 years we have led the way in developing workforce management solutions that enable many of the world's most innovative organizations to optimize their workforce, protect against compliance risks, and increase employee engagement. Now, with the
extensive expertise, resources and global reach of ADP, this winning formula will help us deliver an employee experience for the future through powerful, enterprise-grade workforce management solutions."
About ADP
Designing better ways to work through cutting-edge products, premium services and exceptional experiences that enable people to reach their full potential. HR, Talent, Time Management, Benefits and Payroll. Informed by data and designed for people. Learn more at
ADP .
Safe Harbor Statement
This document and other written or oral statements made from time to time by
ADP
may contain "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Statements that are not historical in nature and which may be identified by the use of words like "outlook," "expects," "assumes," "projects," "anticipates," "estimates," "we believe," "could," "is designed to" and other words of similar meaning, are forward looking statements. These statements are based on management's expectations and assumptions and depend upon or refer to future events or conditions and are subject to risks and uncertainties that may cause actual results to differ materially from those expressed. Factors that could cause actual results to differ materially from those contemplated by the forward-looking statements or that could contribute to such difference include: ADP's
success in obtaining and retaining clients, and selling additional services to clients; the pricing of products and services; the success of our new solutions; our ability to respond successfully to changes in technology, including artificial intelligence; compliance with existing or new legislation or regulations; changes in, or interpretations of, existing legislation or regulations; overall market, political and economic conditions, including interest rate and foreign currency trends and inflation; competitive conditions; our ability to maintain our current credit ratings and the impact on our funding costs and profitability; security or cyber breaches, fraudulent acts, and system interruptions and failures; employment and wage levels; availability of skilled associates; the impact of new acquisitions and divestitures; the adequacy, effectiveness and success of our business transformation initiatives; the impact of any uncertainties related to major natural disasters or catastrophic events; and supply-chain disruptions. ADP
disclaims any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. These risks and uncertainties, along with the risk factors discussed under "Item 1A. Risk Factors" of our most recent Annual Report on Form 10-K, and in other written or oral statements made from time to time by ADP, should be considered in evaluating any forward-looking statements contained herein.
ADP, the ADP logo, and Always Designing for People, are trademarks of
ADP, Inc. All other marks are the property of their respective owners. Copyright © 2024 ADP, Inc. All rights reserved.
SOURCE ADP, Inc.
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STONY BROOK, NY / ACCESSWIRE / October 15, 2024 / Applied DNA Sciences, Inc. (NASDAQ:APDN) (“Applied DNA”), a leader in PCR-based DNA technologies, today announced that Dr. James A. Hayward, president and chief executive officer, will participate in a fireside chat at the 2024 Maxim Healthcare Virtual Summit. Maxim Group LLC is presenting the virtual summit from October 15th to 17th.
Jason McCarthy, Ph.D., Maxim’s senior managing director and head of Biotechnology Research, will interview Dr. Hayward.Applied DNA’s fireside chat will be available for viewing by registered conference attendees on Wednesday, October 16, 2024.
Details for the fireside chat are as follows:
Date: Wednesday, October 16, 2024
Time: 12:50 p.m. EDT
Presenter: James A. Hayward, president and chief executive officer of Applied DNA
Registration: link
About Applied DNA Sciences
Applied DNA Sciences is a biotechnology company developing technologies to produce and detect deoxyribonucleic acid (“DNA”). Using the polymerase chain reaction (“PCR”) to enable both the production and detection of DNA, we operate in three primary business markets: (i) the enzymatic manufacture of synthetic DNA for use in the production of nucleic acid-based therapeutics and the development and sale of a proprietary RNA polymerase (“RNAP”) for use in the production of mRNA therapeutics; (ii) the detection of DNA and RNA in molecular diagnostics and genetic testing services; and (iii) the manufacture and detection of DNA for industrial supply chain security services.
Visit adnas.com for more information. Follow us on X and LinkedIn. Join our mailing list.
Contacts:
Investor Relations contact: Sanjay M. Hurry, 917-733-5573, sanjay.hurry@adnas.com
Web: www.adnas.com
X: @APDN
SOURCE: Applied DNA Sciences
View the original press release on accesswire.com | https://www.biospace.com/news/applied-dna-to-participate-in-the-2024-maxim-healthcare-virtual-summit-on-wednesday-october-16 | 2024-10-15T17:56:45Z |
Attention, American men: Donald Trump and his allies want you to believe your vote says big things about your masculinity.
In the final weeks before the Nov. 5 election, the Republican nominee is amping up his hypermasculine tone and support of traditional gender roles, a reflection of the surgical campaign-within-a-campaign for the votes of men in a showdown with Democratic Vice President Kamala Harris. But where Harris is deploying "dudes" who use bro-ey language and occasional scolding to boost her support particularly among Black and Hispanic males, Trump's camp is meeting men in alpha-male terms, often with crude and demeaning language. That means he appears on podcasts, gaming platforms, and alongside surrogates who define American manliness as a vote for the former Republican president.
“If you are a man in this country and you don’t vote for Donald Trump, you’re not a man,” Turning Point USA founder Charlie Kirk said on his podcast.
Subtle, it's not. But the razor's edge contest between Trump and Harris elevates the importance of small caches of voters who are apathetic or on the fence in the battleground states poised to decide the election. So in a twist on gender and identity politics, both camps are reaching out beyond their ideological bases.
"You're thinking about sitting out or supporting somebody who has a history of denigrating you, because you think that's a sign of strength, because that's what being a man is?" former President Barack Obama scolded Black men last week in Pennsylvania, the largest battleground state. "That's not acceptable."
The polls and history tell the story of the candidates' pursuit of support from men. Trump, who has a long history of denigrating women and bragging about the size of his body parts, won among men in 2016, when he defeated Democrat Hillary Clinton and in 2020, when he lost to President Joe Biden.
This year, men appear to be leaning toward Trump and women toward Harris, though the size of the gap varies across polls.
The nation has an unbroken list of male presidents, who have been presented as father figures, role models and archetypes of American masculinity. Their ranks have included military heroes, including George Washington and Dwight D. Eisenhower. Lawmakers such as Abraham Lincoln, Obama and Biden. A son of the South, Bill Clinton. An actor-turned-governor in Ronald Reagan. And scions like John F. Kennedy and George W. Bush — a Texas rancher.
Then there's Trump, the New York developer and entertainer whose political fortunes have survived a troubled presidential term, 34 felony convictions, a jury verdict finding him liable for sexual assault and two assassination attempts. He rose from a shooting in July, blood-splattered and fist raised, yelling, "Fight, fight, fight!"
He's taking a paternalistic approach as part of a strategy that his campaign hopes could help him not just among men, but also among suburban women who might hesitate supporting him. Trump has long aimed misogyny at women who challenge him.
“I think women like me because I will be your protector,” he told supporters in Aurora, Colorado, on Friday, in remarks about illegal immigration. “The women want protection. They don’t want these people pouring in.”
Last week, Trump called radio host Howard Stern, whose audience is overwhelmingly male, a "BETA MALE" on Truth Social. He recently suggested a female protester at one event should "go back home to Mommy" to "get the hell knocked out of her." His spokesperson, Steven Cheung, tweeted ridicule of Harris' campaign using a sexualized slang term — "cucked" — as apparent shorthand for weakness and submission.
He often muses on stage about his advisers counseling him to change so he would better appeal to women — but then dismisses their advice.
Trump is employing a strategy that has roots in the late 1960s and 1970s, when Republicans realized that framing their opponents as soft and feminine could win them appeal among white working-class men, according to Jackson Katz, an author and the creator of the film “The Man Card: 50 Years of Gender, Power & the American Presidency.”
By positioning Trump as a masculine hero, the campaign has crafted a story, Katz said. “It really is like a soap opera for men.”
In a series of twists on the ever-present gender gap and identity politics, young women are growing more liberal, but young men are not. Most Hispanic women view Harris favorably, but Hispanic men are more divided on her. Alarm bells sounded in Democratic ranks last weekend over concerns about Harris' support among Black men. And some young men feel culturally disaffected in the age of MeToo and Black Lives Matter.
In the election's closing weeks, those dynamics could spell opportunity for the campaigns as they seek to carve more support from whisper-thin slices of the electorate that have yet to choose a side.
“There does seem to be a battle in this campaign to define masculinity,” Jack Z. Bratich, a communications professor at Rutgers University, wrote in an email. Trump, he said, is “harnessing their insecurities and resentments so they feel empowered to vote for him as a way of restoring patriarchal order.”
Harris has unveiled a plan to give Black men more economic incentives and opportunities to thrive. She's sitting for a town hall Tuesday with Charlamagne Tha God, an influential radio host. And vice presidential candidate Tim Walz, fresh off pheasant hunting with reporters in tow and talking football, unveiled an effort to improve the lives of rural voters. She wants you to know that she owns a Glock and that her favorite curse word, as she once said, starts with an "m" and ends with "ah." (After letting out a trademark chuckle, she clarified further: "Not 'e-r.'")
Harris also announced that she'll step outside her ideological comfort zone for her first interview on Fox News. That was enough to activate Trump.
“Fox has grown so weak and soft on the Democrats,” he groused on Truth Social, his social media platform. For his part, Trump is also appearing on Fox News this week in an all-female town hall.
In a sign of how important the votes of men are to Harris' campaign as well: Men are appealing to men to support her. Hence the birth of “Dudes for Harris,” "Hombres con Harris" and Black Men Huddle Up” events in battleground states.
“What the hell are you waiting for?” demanded gravelly voiced actor Sam Elliott in an ad by the anti-Trump Lincoln Project. “Because if it's the woman thing, it's time to get over that.”
___
Kellman reported from London. Associated Press writer Ali Swenson contributed to this report from New York.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/news/politics/trump-emphasizes/VPITDOPE3JHEVGEIESJRYKUTTM/ | 2024-10-15T17:56:45Z |
When Ohioans Vote, We Win
In the past year, politically savvy Ohioans may have noticed an interesting phenomenon at the Ohio Statehouse in Columbus. When members of the legislature discussed issues like protecting abortion access or legalizing recreational cannabis, they were shot down, disregarded, or even outright demonized by Republican lawmakers. When put up for consideration as citizen-led ballot issues, they received enthusiastic votes of support from Ohioans and passed with a sound majority, much to the chagrin of Republican politicians.
So, why do we have such a disconnect between a population that generally supports these issues and a legislative supermajority that vehemently opposes them? The answer is likely something that you’ve been hearing a lot about lately: gerrymandering.
Under our current redistricting laws, GOP politicians enjoy an artificial supermajority and have manipulated our state’s legislative maps to rig the system in ways that even our Republican-controlled state Supreme Court deemed unconstitutional seven times.
An investigation by Newsweek published this past June shows that Ohio is one of the country's most gerrymandered states in the nation. This is an accolade Republicans are fighting hard to keep.
This November, the people of Ohio have a chance to take the power of redistricting out of the hands of politicians and put it into the hands of citizens with Issue 1. Issue 1 would create a citizen-led redistricting commission of equal parts Republicans, Independents, and Democrats, freeing the redistricting process from self-serving elected officials who are often more focused on expanding their manufactured supermajority than creating a map that accurately represents the interests of the people of Ohio.
Ohioans have made it clear that they want redistricting reform, but now they are being gaslighted by our very own Secretary of State, Frank LaRose. Gaslighting is defined as a form of psychological abuse or manipulation in which the person of power attempts to sow self-doubt and confusion in the victim’s mind. Typically, gaslighters seek to gain power and control over people by distorting reality and making them question their judgment and intuition. Over 731,000 Ohioans signed a petition to put redistricting reform on the ballot. The language on that ballot measure has now been manipulated and distorted by LaRose and the Republican politicians that control the Ohio Ballot Board, a committee composed of members of the Ohio House and Senate led by the Secretary of State.
Ballot Board Chair LaRose and his republican counterparts acted in a disingenuous manner when they approved language that paints a citizen-led, anti-gerrymandering measure as an attack on the redistricting process and approved language that says the new commission would be, “Required to gerrymander the legislative and congressional district lines.”
Nothing could be further from the truth. In fact, his decision to write and adopt misleading and deceptive language jeopardizes the integrity of our election process. This is all part of an effort to gaslight the people of Ohio and maintain a supermajority that will allow those in power to continue to use the power of the pen and the state legislature as a weapon against the people of Ohio.
The language that will appear on the November ballot is one in a series of Frank LaRose’s recent attacks on our state's election process. In a letter to the President of the Senate and Speaker of the House, he again attempted to suppress voting rights in this state by suggesting they pass legislation to ban ballot drop boxes, require proof of citizenship for voter registration, and force voters to cast provisional ballots for voter registration if their voter registration differs from the information on file with the Bureau of Motor Vehicles or the Social Security Administration (BMV/SSA).
Let me be clear, our Secretary of State is using his power to push a political agenda making it harder for Ohioans to vote—the antithesis of the Secretary of State’s job!
We have a chance to cut through the lies and deceit and make Ohio a better, more representative democracy. Early voting in Ohio begins October 8. I plan to vote yes on Issue 1, for citizens, not politicians, to draw districts that will lead Ohio into a more balanced representative future where the people choose their representatives, not the other way around.
Nickie J. Antonio serves as Senate Minority Leader. She represents Ohio’s 23rd Senate District, which includes the majority of Cleveland, Parma, Parma Heights, Lakewood, and Bratenahl.
Nickie Antonio
State Senator Nickie J. Antonio (D-Lakewood) is honored to be serving in the Ohio Senate, representing District 23, and in leadership as the Minority Leader. Antonio, who was elected to the Senate in 2018, previously spent eight years in the Ohio House of Representatives, where she served District 13 and was also a member of leadership. Antonio has served as a Lakewood City Councilmember, Executive Director of an outpatient drug and alcohol treatment program for women, Adjunct Professor, and a teacher for children with special needs.
Antonio serves as Highest Ranking Member on the Senate Health, Transportation, and Rules and Reference Committees. Additionally, she is a member of the Ohio House Democratic Women's Caucus, previously as chair, and is the State Director for the National Women Legislators� Lobby.
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She has been a dedicated champion of workers� rights, high-quality education, local governments, equal rights for women and the LGBT community, health care for all, and fighting the opioid crisis.
Antonio is recognized as a leader who reaches across the aisle to get things done. As a result, she championed Ohio�s historic adoption of open records law (S.B. 23/H.B. 61) and step therapy reform law (S.B. 265/H.B. 72). Last General Assembly, Antonio passed legislation to abolish the shackling of pregnant inmates (S.B. 18/H.B. 1) and to require pharmacist education for dispensing life-saving naloxone (S.B. 59/H.B. 341). During her tenure in the Ohio legislature, Antonio introduced the Ohio Fairness Act, which would provide civil rights protections for members of the LGBTQ community. She continues to work to remedy and end Ohio�s use of the death penalty, as well as on an array of other bills focused on improving the lives of all Ohioans. Antonio continues to be an established expert in health policy in the General Assembly.
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The first in her family to graduate from college, she holds both an MPA and a B.S. Ed. from Cleveland State University, and she was named a CSU Distinguished Alumni in 2013. She is also an alumnus and Bohnett Fellow of the Kennedy School Harvard Leadership Program (2011) and has been the recipient of numerous awards as legislator of the year from various organizations during her tenure.
Her daughters, Ariel and Stacey, have made Antonio and her wife, Jean Kosmac, very proud as the girls engage in their adult life journeys. | https://lakewoodobserver.com/read/2024/10/15/when-ohioans-vote-we-win | 2024-10-15T17:56:48Z |
Boeing plans to lay off about 10% of its workers in the coming months, about 17,000 people, as it continues to lose money and tries to deal with a strike that is crippling production of the company’s best-selling airline planes.
New CEO Kelly Ortberg told staff in a memo Friday that the job cuts will include executives, managers and employees.
The company has about 170,000 employees worldwide, many of them working in manufacturing facilities in the states of Washington and South Carolina.
Boeing had already imposed rolling temporary furloughs, but Ortberg said those will be suspended because of the impending layoffs.
The company will further delay the rollout of a new plane, the 777X, to 2026 instead of 2025. It will also stop building the cargo version of its 767 jet in 2027 after finishing current orders.
Boeing has lost more than $25 billion since the start of 2019.
About 33,000 union machinists have been on strike since Sept. 14. Two days of talks this week failed to produce a deal, and Boeing filed an unfair-labor-practices charge against the International Association of Machinists and Aerospace Workers.
As it announced layoffs, Boeing also gave a preliminary report on its third-quarter financial results — and the news is not good for the company.
Boeing said it burned through $1.3 billion in cash during the quarter and lost $9.97 per share. Industry analysts had been expecting the company to lose $1.61 per share in the quarter, according to a FactSet survey, but analysts were likely unaware of some large write-downs that Boeing announced Friday — a $2.6 billion charge related to delays of the 777X, $400 million for the 767, and $2 billion for defense and space programs including new Air Force One jets, a space capsule for NASA and a military refueling tanker.
The company based in Arlington, Virginia, said it had $10.5 billion in cash and marketable securities on Sept. 30. Boeing is schedule to release full third-quarter numbers on Oct. 23.
The strike has a direct bearing on cash burn because Boeing gets half or more of the price of planes when it delivers them to airline customers. The strike has shut down production of the 737 Max, Boeing's best-selling plane, and 777x and 767s. The company is still making 787s at a nonunion plant in South Carolina.
“Our business is in a difficult position, and it is hard to overstate the challenges we face together,” Ortberg told staff. He said the situation “requires tough decisions and we will have to make structural changes to ensure we can stay competitive and deliver for our customers over the long term.”
Ortberg took over at Boeing in August, becoming the troubled company’s third CEO in less than five years. He is a longtime aerospace-industry executive but an outsider to Boeing.
The new CEO faces many challenges to turn the company around.
The Federal Aviation Administration increased scrutiny of the company after a panel blew out of a Max during an Alaska Airlines flight in January. Boeing has agreed to plead guilty and pay a fine for conspiracy to commit fraud tied to the Max, but relatives of the 346 people who died in two Max crashes want tougher punishment.
And Boeing got attention for all the wrong reasons when NASA decided that a Boeing spacecraft wasn’t safe enough to carry two astronauts home from the International Space Station.
Copyright 2024 NPR | https://www.ideastream.org/2024-10-11/boeing-will-lay-off-10-of-employees-as-a-strike-shuts-down-airplane-production | 2024-10-15T17:56:48Z |
Tate McRae's new era is full speed ahead.
After dropping her new song and video, "It's ok I'm ok," the Canadian star is now teasing yet another new song. In a clip on Instagram, she sings, "I just want your two hands on me/ at all times, baby." She captioned the post, "Another one alreadddyyy."
The song is officially called "2 Hands," and you can presave it now. Tate joked on TikTok, "No chance i wrote a happy song."
Prior to that, she posted a carousel of photos. One photo showed a white board with a list of numbers, which looks an awful lot like an album track listing, and next to each of them is a heart. She captioned that post, "Stay tuned." Tate's musical collaborator Ryan Tedder liked both posts.
One fan wrote in the comments, "the whiteboard out already???? oh ur working HARD." Other fans started begging for the release of the song and the album. "Ok Tate feed us," wrote one. "TM3 is definitely sooner than we think omg," another wrote.
Tate's most recent album, Think Later, came out in December 2023.
Copyright © 2024, ABC Audio. All rights reserved. | https://www.hits973.com/news/tate-mcrae-teases/4PJER2K44S65X6TVVOI6VNU3KU/ | 2024-10-15T17:56:48Z |
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The union representing some 2,700 health care workers at the University of Michigan announced it reached a tentative, three-year agreement with the health system Monday night, just hours before a one-day strike was set to begin on October 15.
This is the first agreement reached for the newly formed collective bargaining unit of respiratory therapists, phlebotomists, ECMO specialists, clerical staff and others.
“We’re glad and relieved to have reached a tentative agreement with the University that allows workers to move forward and keep their focus on taking care of Michiganders,” said Larry Alcoff, SEIU Healthcare’s deputy trustee, in a statement.
“This agreement reflects our appreciation for these incredibly valuable members of our team. As always, our goal is to attract and retain the best health care professionals who can provide the high quality care we deliver every day to our patients,” said Dr. David Miller, president of U of M Health, in a statement. “Both negotiating teams worked tirelessly to reach this agreement, embodying the core values of teamwork, collaboration, caring and integrity that set Michigan Medicine apart as a premier academic medical center.”
SEIU Healthcare Michigan will schedule a ratification vote among its members in the coming weeks.
Editor's note: U of M holds Michigan Public's broadcast license. | https://www.wemu.org/michigan-news/2024-10-15/one-day-strike-averted-at-michigan-medicine | 2024-10-15T17:56:51Z |
CAIRO — (AP) — The Grand Egyptian Museum will partially open its main galleries on Wednesday, including 12 halls that exhibit aspects of ancient Egypt, as part of a trial run, officials said Tuesday.
The museum, a mega-project near the famed Giza Pyramids which has cost well over $1 billion so far, will open the halls for 4,000 visitors as a trial run until the official opening date, which is yet to be announced, according to Al-Tayeb Abbas, assistant to the minister of antiquities.
The opening of the museum, which has been under construction for more than a decade, has been repeatedly delayed for various reasons, including the COVID-19 pandemic.
More than 100,000 artifacts of Egypt's ancient treasures will be displayed in the world's largest archaeological museum, according to the Egyptian state information website.
Abbas told the AP that the trial run starting Wednesday would help prepare for the full opening by providing a deeper understanding of issues related to operations such as identifying overcrowded areas across the museum.
The displays across the 12 halls tap into issues related to society, religion, and doctrine in ancient Egypt, he added. All open-style halls have been classified by dynasty and historical order, and each will showcase at least 15,000 artifacts.
Eras that will be exhibited in the main galleries include the Third Intermediate Period (about 1070-664 B.C.), Late Period (664-332 B.C.), Graeco-Roman Period (332 B.C.-395 A.D.), New Kingdom (1550-1070 B.C.), Middle Kingdom (2030-1650 B.C.), and Old Kingdom (2649-2130 B.C.). One of the halls displays statues of “Elite of the King,” members of the royal family and high-ranking officials who worked in the army, priesthood, and the government.
Parts of the site have already been open for limited tours since late 2022 to test visitors’ experience and the museum’s operational preparedness.
Aude Porcedde, a Canadian tourist who visited several sections, told the AP she was amazed by the museum, adding that Egyptian civilization is important for her and for the world to know more about.
“There is a lot of history and a lot of things we are not aware of, especially coming from the other side of the world, and seeing everything here and learning from the locals has been great,” said Costa Rican tourist Jorge Licano.
The grand staircase, six stories high and with a view of the pyramids, and the commercial area are open to the public, showcasing monuments and artifacts that include sarcophagi and statues. Other parts of the museum, including the King Tutankhamun treasure collection, are set to open at later dates.
All halls are equipped with advanced technology and feature multimedia presentations to explain the lives of the ancient Egyptians, including its kings, according to Eissa Zidan, Director-General of the Preliminary Restoration and Antiquities Transfer at the museum.
One of the halls will use virtual reality to explain the history of burial and its development throughout ancient Egypt.
“The museum is not only a place to display antiquities, but it also aims to attract children to learn about ancient Egyptian history ... The museum is a gift to all the world,” Zidan told the AP.
-------------------------------------------------------------------------------------------
Associated Press journalist Fatma Khaled contributed to this report from Cairo.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.actionnewsjax.com/entertainment/egypts-long-delayed/QL7LODGIJJDOBFCG6JRU7ABEYQ/ | 2024-10-15T17:56:51Z |
LONDON — (AP) — Anguilla is raking in extra revenue from registration fees for its .ai web domain thanks to the artificial intelligence boom, but it's not the only place cashing in on demand for websites with distinctive address endings.
Here's a look at some other places cashing in on their unique top-level domains:
TUVALU
Tuvalu is a string of coral atolls, scattered over hundreds of miles in the Pacific Ocean, located midway between Australia and Hawaii. It has one of the world's smallest economies and its low-lying islands are vulnerable to climate change, but it does have a very valuable resource: the .tv web domain. Royalties from .tv, which web users might assume is short for television, have been climbing, especially after videogame streaming platform Twitch licensed the web address twitch.tv.
LIBYA
The North African country, which has been plagued by turmoil since longtime dictator Moammar Gadhafi's death in 2011, isn't readily associated with internet culture. But Libya controls web addresses that end in .ly, which have become widely used as a so-called domain hack for websites with English names that end in -ly. Well-known examples include bit.ly, used by the weblink shortening service Bitly, and parse.ly, the website for online analytics platform Parse.ly.
MONTENEGRO
This Balkan country became an independent nation after the breakup of Yugoslavia. It's one of Europe's smaller countries — about 620,000 people — bordered by the Adriatic Sea, Bosnia, Kosovo, Serbia and Albania. Montenegro was assigned the .me web domain, which has become popular with people who want to claim their pronoun for personal branding.
Websites ending in .me are “often used for personal websites, portfolios, blogs and online resumes or portfolios because ‘me’ can be seen as a way to personalize an online presence,” website builder Wix says.
COLOMBIA
Websites that end in .co aren't from a generic web domain for companies, like .com sites. The .co domain is assigned to Colombia, but the South American country allows anyone to sign up for its web addresses. Internet registrar GoDaddy says more than 2 million .co web domains have been claimed, including addresses claimed by Big Tech names like Amazon which uses it to redirect online shoppers to its .com home page. Google, meanwhile, informs visitors to g.co that the link is it's official shortcut.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/news/technology/countries-that-have/NWED4OGRYBG7NK4MJEIVVQJUPY/ | 2024-10-15T17:56:52Z |
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- Near Infrared Light Delivered Transcranially Can Treat Traumatic Brain Injury
- POC EEG Device Quickly Identifies Non-Convulsive Seizures in Acute Care Environments
- Machine-Learning Tool to Improve Clinical Outcomes for Stroke Patients with Large Blood Vessel Blockages
- Cutting-Edge Intelligent Medical Sutures Accelerate Wound Healing
- Fluorescent Dye Reveals Biochemical Conversations Between Cartilage and Bone in Early Osteoarthritis
- Glowing Approach Helps Surgeons Assess Neural Blood Flow in Chronic Nerve Compression Neuropathy
- Predictive Model Identifies Best Patients for Minimally Invasive Epilepsy Surgery
- Light-Driven Micro-Robot Designed to Swim Autonomously in Viscous Liquids Could Be Used for Unblocking Blood Vessels
- Novel Approach Combines Advanced Robotics and Low-Field MRI Technology for Incisionless Prostate Surgery
- Fast OCT System Integrated into Neurosurgical Microscope Identifies Tumor Margins During Brain Surgery
- First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds
- Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization
- Game-Changing Innovation in Surgical Instrument Sterilization Significantly Improves OR Throughput
- Next Gen ICU Bed to Help Address Complex Critical Care Needs
- Groundbreaking AI-Powered UV-C Disinfection Technology Redefines Infection Control Landscape
- BD Completes Acquisition of Critical Care from Edwards Lifesciences
- ZOLL to Acquire Vyaire Medical’s Ventilator Business
- Getinge Acquires Organ Transport Products and Services Company Paragonix Technologies
- Stryker Acquires care.ai to Boost AI-Driven Healthcare
- Johnson & Johnson Acquires Cardiovascular Specialist V-Wave
- Strategic Collaboration to Develop and Integrate Generative AI into Healthcare
- AI-Enabled Operating Rooms Solution Helps Hospitals Maximize Utilization and Unlock Capacity
- AI Predicts Pancreatic Cancer Three Years before Diagnosis from Patients’ Medical Records
- First Fully Autonomous Generative AI Personalized Medical Authorizations System Reduces Care Delay
- Electronic Health Records May Be Key to Improving Patient Care, Study Finds
- New 8-Minute Blood Test to Diagnose or Rule Out Heart Attack Shortens ED Stay
- 5-Minute Multiplex PCR Testing System to Redefine Point-Of-Care Diagnostics
- POCT for Infectious Diseases Delivers Laboratory Equivalent Pathology Results
- Cartridge-Based Hemostasis Analyzer System Enables Faster Coagulation Testing
- Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing | https://www.hospimedica.com/artificial-intelligence/articles/294802770/clinical-model-accurately-predicts-risk-of-hip-fractures-in-elderly.html | 2024-10-15T17:56:51Z |
James M. Acton | Carnegie Endowment for International Peace
The danger of space-based nuclear weapons isn’t just that Moscow might actually use them. It’s that Washington knows Moscow might actually use them. As a result, the United States might attack Putin’s space nukes before he can push the button—which, in turn, might incentivize Putin to jab his finger as fast as he can.
Karim Sadjadpour and Nicole Grajewski | Carnegie Endowment for International Peace
Few geopolitical alignments are more consequential to global security and world order than the Russia-Iran partnership of defiance…Both countries are ruled by embattled autocrats—eighty-five-year-old Ayatollah Ali Khamenei in Iran and seventy-one-year-old Vladimir Putin in Russia—who have collectively been in power for over five decades. The two men are united in their opposition to the United States and the liberal international order, in particular eastward NATO expansion and America’s political, military, and cultural influence in the Middle East.
Shira Rubin and Ellen Nakashima | The Washington Post
Israeli Prime Minister Benjamin Netanyahu has told the Biden administration he is willing to strike military rather than oil or nuclear facilities in Iran, according to two officials familiar with the matter, suggesting a more limited counterstrike aimed at preventing a full-scale war…When Biden and Netanyahu spoke Wednesday — their first call in more than seven weeks after months of rising tensions between the two men — the prime minister said he was planning to target military infrastructure in Iran, according to a U.S. official and an official familiar with the matter.
Jennifer Hiller | The Wall Street Journal
Google will back the construction of seven small nuclear-power reactors in the U.S., a first-of-its-kind deal that aims to help feed the tech company’s growing appetite for electricity to power AI and jump-start a U.S. nuclear revival.Under the deal’s terms, Google committed to buying power generated by seven reactors to be built by nuclear-energy startup Kairos Power. The agreement targets adding 500 megawatts of nuclear power starting at the end of the decade, the companies said Monday.
Hans Kristensen | Federation of American Scientists
NATO today began its annual tactical nuclear weapons exercise in Europe. Known as Steadfast Noon, the two-week long exercise involves more than 60 aircraft from 13 countries and more than 2,000 personnel, according to a NATO press release. That is slightly bigger than last year’s exercise that involved “up to 60” aircraft. The exercise is co-hosted by Belgium and the Netherlands at the Kleine Brogel and Volkel airbases, respectively. Flight operations are focused over the North Sea and surrounding countries including Belgium, Denmark, Germany, the Netherlands, and the United Kingdom. NATO says a total of eight bases are involved.
Hannah Beech, Hisako Ueno and Kiuko Notoya | The New York Times
On Friday, Nihon Hidankyo, a collective of Japanese atomic bomb survivors, was awarded the 2024 Nobel Peace Prize for its decades-long campaign to rid the world of nuclear weapons. The group was honored by the Norwegian Nobel Committee for “demonstrating through witness testimony that nuclear weapons must never be used again.” The survivors of the bombings — more than 100,000 are still living — “help us to describe the indescribable, to think the unthinkable, and to somehow grasp the incomprehensible pain and suffering caused by nuclear weapons,” Jorgen Watne Frydnes, the committee chairman, said. | https://carnegieendowment.org/programs/nuclear-policy/proliferation-news/proliferation-news-101524 | 2024-10-15T17:56:51Z |
MICHEL MARTIN, HOST:
America's biggest pharmacy chains are not healthy. CVS and Walgreens are closing hundreds of stores and rethinking their role in our lives. NPR's Alina Selyukh explains why.
ALINA SELYUKH, BYLINE: Pick a city, any city in America, and you'll probably find a corner just like this one in Washington, D.C., with a Starbucks, a sandwich shop and a CVS or a Walgreens or sometimes both.
BRIAN TANQUILUT: There are very, very, very few spots in the U.S. where you have to drive more than 5 miles to get to a pharmacy.
SELYUKH: Brian Tanquilut at the investment bank Jefferies sums up the first and the simplest part of why big pharmacies have languished - there are so many. They've gobbled up mom-and-pop shops, signed long leases for prime real estate, and now Walgreens says a quarter of its stores don't make money. And if you can't grow by adding stores, you have to grow the business inside the stores.
NEIL SAUNDERS: The bigger problem is that the stores that they have are not very good.
SELYUKH: That's Neil Saunders with the analytics firm GlobalData, delivering the bitter pill that's the second problem.
SAUNDERS: Their kind of very blunt response is to close stores. They do need to close some stores, but they also need to focus on making the stores they do have work better operationally.
SELYUKH: This problem is chronic. Walk with me through a CVS, and you quickly see it's understaffed while trying to be two things at once.
Getting to the prescription counter, which is arguably the heart of this operation, means first walking through a convenience store with snacks and laundry detergent. Most of that is locked up to prevent theft.
All these shelves were meant to boost profits, except sales here have sagged for years in a losing battle with Amazon, Walmart, grocery stores, dollar stores. So one big idea is for pharmacies to ditch the store and focus on the pharmacy.
(SOUNDBITE OF ARCHIVED RECORDING)
AUTOMATED VOICE: Please remember to take your receipt.
SELYUKH: But here lies the third and most complicated problem - the pharmacy business has been getting less and less profitable. There have been constant changes to how CVS and Walgreens get paid for filling prescriptions, and it has to do with a big shift years back in the balance of power between pharmacies and insurers.
TANQUILUT: Historically, there was a view that there was a lot of customer loyalty to their specific retail pharmacy...
SELYUKH: Brian Tanquilut.
TANQUILUT: ...And that patients or consumers would be all up in arms if they were forced to move their prescriptions.
SELYUKH: This idea was put to a test about a decade ago when Walgreens got into a public fight with a company called Express Scripts. It's one of the middlemen that helps insurers negotiate drug prices. They're called pharmacy benefit managers. Walgreens and Express Scripts played a game of chicken over how much Walgreens should earn from prescriptions, and Walgreens lost. Millions of people simply had to go elsewhere for their medicine.
TANQUILUT: That proved that patient loyalty is not to the retail pharmacy, but it actually is whatever my insurance is willing to pay.
SELYUKH: Beyond these three big problems, there are plenty more - a poor online presence, various government fines. The pharmacy chains have attempted to change. CVS actually bought one of those middlemen, called Caremark, and the insurance company Aetna. Both CVS and Walgreens added primary care clinics, a project that could be revolutionary but takes tremendous time and money. Here's Saunders.
SAUNDERS: Out of the two of them, there's no doubt that Walgreens is in real trouble, whereas CVS is just in a difficult spot.
SELYUKH: Walgreens has now shaken up leadership. CVS is reportedly considering a breakup to undo its mergers with Caremark and Aetna. Both chains are also proposing new ways to negotiate drug prices, hoping that's the big shot in the arm that they need.
Alina Selyukh, NPR News.
(SOUNDBITE OF ARCHIVED RECORDING)
AUTOMATED VOICE: Thank you for shopping at CVS. Transcript provided by NPR, Copyright NPR.
NPR transcripts are created on a rush deadline by an NPR contractor. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record. | https://www.ideastream.org/2024-10-11/cvs-and-walgreens-close-stores-rethink-their-role-in-our-lives | 2024-10-15T17:56:54Z |
SHENZHEN, China, Oct. 15, 2024 /PRNewswire/ -- On October 15, 2024, the list of selected candidates for the oral report of the American Association for the Study of the Liver (AASLD 2024) annual meeting was officially announced online. The abstract of the Phase II clinical study (CGZ203 trial) on the treatment of non-alcoholic steatohepatitis (NASH)/metabolic associated steatohepatitis (MASH) with our independently developed Chiglitazar (Carfloglitazar) will be presented orally at the annual meeting to be held in San Diego, USA from November 15th to 19th.
The incidence of metabolic associated fatty liver disease (MAFLD) in China is over 25%, of which about 25% of patients will further develop MASH. Among patients with metabolic syndrome, this proportion is even higher. However, Currently, there is only one approved thyroid hormone receptor beta (THR - β) agonist drug in the global regulated market for the treatment of MASH. China has not yet approved any drugs for this treatment field.
CGZ203 is a randomized, double-blind, placebo-controlled, phase II clinical trial aimed at evaluating the safety and preliminary efficacy of Chiglitazar (Carfloglitazar) monotherapy in the MASH population. Patients clinically diagnosed with MASH were randomly assigned to receive Chiglitazar 48mg (n=42), 64mg (n=41), or placebo (n=21) at a ratio of 2:2:1, orally once daily for a treatment period of 18 weeks.
The study results showed that the liver fat content (LFC) evaluated by MRI-PDFF decreased from baseline by 28.1% and 39.5% respectively after 18 weeks of treatment with Chiglitazar 48mg or 64mg (decrease of 3.2% in the Placebo). The proportion of patients achieved over 30% decrease in LFC was 40.5% and 65.9% respectively (14.3% in the placebo). The plasma biochemical indicators related to chronic inflammation and liver injury, such as CK-18, liver transaminase, bilirubin, etc., also significantly decreased after treatment with Chiglitazar. The alanine aminotransferase (ALT) level in the high-dose group decreased by more than 50% from baseline, and the ALT level returned to the normal range in more than 70% of patients.
Regarding to liver fibrosis evaluated by Fibroscan LSM, Chiglitazar produced a dose - and time-dependent decrease in liver stiffness values, with the high-dose group showing a decrease of 2 Kpa in LSM values after 18 weeks of treatment. When comparing with the placebo, Chiglitazar groups showed comparable good safety. In terms of potential side effects related to PPAR agonists, there was no significant body weight gain in the Chiglitazar treatment groups, whiles a slight decrease in the high-dose group; and only one mild edema occurred in the low-dose group.
This study demonstrates the good safety tolerance and preliminary promising efficacy of Chiglitazar on the multiple pathological aspects such as liver fat accumulation, chronic inflammation, and liver fibrosis in patients with MASH, although, it remains to be confirmed in further clinical trials.
ABSTRACT PRESENTATION DETAILS
Abstract Number: 2603
Session Date / Time: 11/17/2024，2:00pm - 3:30 pmTitle: MASLD and MASH - New Therapies Type: Abstract Parallel
Speaker: Professor You Hong, Beijing Friendship Hospital Affiliated to Capital Medical University
Presentation: A randomized, double-blind, placebo-controlled phase 2 trial to evaluate the efficacy and safety of Chiglitazar in NASH patients
Presentation Time: 2:15 pm - 2:30 pm
Presentation Duration: 15 minutes
Publication Number: 54
About Chiglitazar:
Chiglitazar is a new mechanism hypoglycemic drug independently developed by the company, and also the first fully PPAR agonist approved to treat type 2 diabetes in the world. At present, Chiglitazar sodium has been approved for blood glucose control in adult patients with type 2 diabetes. It can be taken alone or combined with metformin.The Phase II clinical study of monotherapy for the treatment of nonalcoholic steatohepatitis (NASH) has concluded and achieved its primary endpoint.
Chiglitazar Sodium targets insulin resistance, a core mechanism in the occurrence and development of type 2 diabetes mellitus (T2DM). It moderately activates all three PPAR subtypes to achieve a dynamic balance of glucose, lipid, energy, and protein metabolism. Preliminary comprehensive clinical studies indicate that Chiglitazar Sodium has excellent safety, pharmacokinetic, and pharmacodynamic profiles, demonstrating efficacy in regulating blood glucose, blood lipids, and energy in patients with T2DM.
About Chipscreen:
Chipscreen Biosciences is an innovative drug company driven by core technologies with globally competitive pipelines. As a pioneer in drug innovation & development in China, adhering to the concept of “Constant Innovation for Life”, we focus on developing revolutionary innovative drugs with new mechanisms of action, to address patients’ pressing clinical needs. Our complete industry chain that covers early exploratory discovery through commercialization allows us to provide innovative Chinese drugs for patients worldwide.
With a global development strategy based on early-stage research in China, Chipscreen Biosciences has leveraged the top scientists and teams with extensive experience in related fields from the Shenzhen Small Molecule Early R&D Center and Chengdu Small Molecule Early R&D Center to create an integrated technology platform based on AI-driven design and chemical genomics, which spanned the whole process from basic science to clinical translation. We have successfully developed first-in-class and best-in-class innovative drugs. Currently, 2 drugs with 6 indications have been marketed worldwide. In addition, we have launched a number of R&D projects with differentiated advantages and global competitiveness in the five major areas, including malignant tumors, metabolic diseases, autoimmune diseases, central nervous system diseases, and antivirals.
Chipscreen Biosciences has formed a global industrial layout consisting of Shenzhen Head Office/R&D Center/GMP production base, Chengdu Regional Head Office/R&D Center/GMP production base, Beijing Branch, Shanghai Branch, and Chipscreen Biosciences (USA) Co., Ltd. Meanwhile, as one of the first batches of national “innovative drug incubation bases” and national high-tech enterprises, Chipscreen Biosciences has independently undertaken many national “863" plans and national major science and technology projects, such as “10th five-year plan”, “11th five-year plan”, “12th five-year plan” and “13th five-year plan”, and National Science and Technology primary Project for Innovative Drug Development. We have filed over 660 invention patents in China and worldwide, with over 180 granted.
View original content:https://www.prnewswire.com/news-releases/chiglitazar-for-the-treatment-of-mash-phase-ii-clinical-study-selected-for-oral-presentation-at-the-2024-american-liver-disease-annual-meeting-302276529.html
SOURCE Shenzhen Chipscreen Biosciences, Ltd. | https://www.biospace.com/news/chiglitazar-for-the-treatment-of-mash-phase-ii-clinical-study-selected-for-oral-presentation-at-the-2024-american-liver-disease-annual-meeting | 2024-10-15T17:56:55Z |
SAN FRANCISCO — A Navy parachutist was off-target and instead of landing where he should have, he landed on a mother and daughter during San Francisco’s Fleet Week.
The jump happened on Sunday at the city’s Marina Green, the designated target, SFGate reported.
But instead of hitting the spot where the sailor was supposed to land, he fell onto a group of spectators on the area’s perimeter.
The mother and daughter, who were not identified, bore the brunt of the impact but had minor injuries. They were still taken to an area hospital by ambulance, fire department officials said.
The crash was under investigation. It is not known why the jump went bad, KRON reported.
The U.S. Navy released a statement saying, “Our thoughts are with the individual and their family. Safety is our number one priority. We cannot immediately assess what happened; however, we will review this incident to determine the cause,” KRON reported.
© 2024 Cox Media Group | https://www.hits973.com/news/trending/navy-parachutist-lands-mother-child-during-fleet-week-jump/2PYZJGIEO5FAXJOBBX6CXRYMAA/ | 2024-10-15T17:56:55Z |
Wall Street was moderately upbeat last week. The S&P 500, the Dow Jones and the Nasdaq Composite added 1.1%, 1.2% and 1.1%, respectively. Among the key developments, the Federal Reserve’s September meeting minutes revealed the conflicting perspectives. While a "substantial majority" of officials supported a 50-basis-point reduction, some preferred a smaller 25-basis-point cut.
The annual inflation rate in the United States slowed for the sixth successive month to 2.4% in September 2024, the lowest since February 2021, from 2.5% in August. However, the figure came above the forecast of 2.3%. The monthly core inflation rate remained at 0.3%, the same as in August but above the forecast of 0.2%. Inflation accelerated for food (2.3% versus 2.1%) and transportation (8.5% versus 7.9%).
Against this backdrop, below, we highlight a few exchange-traded funds (ETFs) that gained the most last week.
Inverse/Leveraged ETFs in Focus
Defiance Daily Target 1.75x Long MSTR ETF (MSTX) – Up 35.9%
MicroStrategy shares surged 18% last week, with prominent gains noticed on Oct. 11, 2024. Since the company adopted a bitcoin-centered strategy, its shares have been on a surge.
GraniteShares 2x Long UBER Daily ETF (UBRL) – Up 33.3%
Shares of Uber UBER and Lyft LYFT surged on Oct. 11, 2024, following Tesla’s TSLA not-so-exciting robotaxi event, which failed to meet expectations, raising concerns among ridesharing investors. Tesla’s much-anticipated unveiling of robotaxi lacked some crucial details about the potential ridesharing app. This boosted competitor Uber's stock to an all-time high. Uber shares jumped 10.8% on that day.
Defiance Daily Target 2X Long SMCI ETF (SMCX) – Up 30.6%
Super Micro Computer SMCI stock price jumped 15% last week. The company designs, develops, and sells energy-efficient, application-optimized server solutions based on the x86 architecture. The company recently said that it shipped more than 100,000 GPUs with direct liquid cooling solutions for a few very large data centers built to power AI applications. Hence, its gain is related to the ongoing AI boom.-
Tradr 2X Short TSLA Daily ETF (TSLQ) – Up 28.5%
Tesla shares slumped 8.8% on Oct. 11. On Oct. 10, 2024, Tesla introduced its CyberCab, an autonomous vehicle designed for ridesharing, along with a 20-seater "RoboVan." Tesla CEO Elon Musk claimed that the CyberCab would be priced under $30,000 and envisioned individuals operating fleets of these vehicles as an alternative to Uber and Lyft. Despite this, analysts were underwhelmed by the lack of concrete information regarding Tesla’s plans to launch a ridesharing platform.
GraniteShares 2x Long PLTR Daily ETF (PTIR) – Up 17.2%
Palantir Technologies’ PLTR stock gained 9.1% last week. The company builds and deploys software platforms for the intelligence community principally in the United States. Among the recent news, Palantir owns 8.7% of the struggling electric vehicle startup Faraday Future. The data-mining company is eyeing an EV foothold.
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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. | https://www.nasdaq.com/articles/5-single-stock-etfs-ruled-last-week | 2024-10-15T17:56:56Z |
(MENAFN- PR Newswire)
SAN FRANCISCO
, Oct. 15, 2024 /PRNewswire/ -- Instacart (NASDAQ: CART ) today announced it will report its third quarter 2024 financial results after market close on Tuesday, November 12, 2024. The company's third quarter 2024 Shareholder Letter will be available on Instacart's Investor Relations website at .
Instacart management will also host a conference call to discuss the company's results at 2:00 p.m. Pacific Time (5:00 p.m. Eastern Time) on Tuesday, November 12. To access a live webcast of the conference call, please visit the Investor Relations website at . After the call concludes, a replay will be made available on the Investor Relations website.
Instacart uses and intends to continue to use its Investor Relations website as a means of disclosing material nonpublic information and for complying with its disclosure obligations under Regulation FD. Accordingly, investors should monitor Instacart's Investor Relations website, press releases, SEC filings, public conference calls, and public webcasts, in addition to following Instacart's blog, which is located at .
About Instacart
Instacart, the leading grocery technology company in North America, works with grocers and retailers to transform how people shop. The company partners with more than 1,500 national, regional, and local retail banners to facilitate online shopping, delivery and pickup services from more than 85,000 stores across North America on the Instacart Marketplace. Instacart makes it possible for millions of people to get the groceries they need from the retailers they love, and for approximately 600,000 Instacart shoppers to earn by picking, packing and delivering orders on their own flexible schedule. The Instacart Platform offers retailers a suite of enterprise-grade technology products and services to power their e-commerce experiences, fulfill orders, digitize brick-and-mortar stores, provide advertising services, and glean insights. With Instacart Ads, thousands of CPG brands – from category leaders to emerging brands – partner with the company to connect directly with consumers online, right at the point of purchase. With Instacart Health, the company is providing tools to increase nutrition security, make healthy choices easier for consumers, and expand the role that food can play in improving health outcomes. For more information, visit
, and to start shopping, visit
. Maplebear Inc. is the registered corporate name of
Instacart.
SOURCE Maplebear Inc. dba Instacart
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Getty Images/GoalSoham MukherjeeA family feud! Carlo Ancelotti and assistant coach son Davide at odds over role of Real Madrid starlet Arda GulerReal MadridC. AncelottiA. GulerLaLigaCarlo Ancelotti and his son Davide, Real Madrid's assistant coach, are said to have had disagreements over Arda Guler.Article continues belowArticle continues belowArticle continues belowAncelotti struggling to find Real Madrid balanceHas used Guler sporadically from the benchDavide wants a more prominent role for the TurkFollow GOAL on WhatsApp! 🟢📱Article continues below | https://www.goal.com/en-za/lists/carlo-ancelotti-coach-son-davide-real-madrid-arda-guler/bltb433d3ba7cd48223 | 2024-10-15T17:56:56Z |
Walgreens plans to close 1,200 stores over the next three years, the pharmacy chain said on Tuesday. It's part of the company's plan for a turnaround, as it faces retail competition and lower prescription payouts.
Chief Executive Tim Wentworth said about a quarter of the company’s stores are unprofitable. Walgreens has been on a $1-billion cost-cutting spree. It's already been shutting some stores, shaking up leadership and renegotiating its deals with insurers.
Walgreens, which also owns the British drugstore chain Boots, reported a net loss of $3 billion in the latest quarter. This was actually better than expected, with sales growing 6%.
Walgreens isn't the only big pharmacy chain attempting a turnaround. Rite Aid last month emerged from bankruptcy; CVS has also closed stores and reportedly weighs a breakup to undo its mergers with the insurance company Aetna and with Caremark, a pharmacy benefits manager.
The convenience-store part of pharmacy chains has been losing shoppers to Amazon, Walmart, Costco, grocery stores and dollar stores. Many of those rivals also fill prescriptions, competing for pharmacy customers, too.
Pharmacy chains have over-expanded to thousands of locations over the years, signing long-term leases for pricey corner locations. But many shoppers have criticized the quality of the stores, complaining about understaffing and the inaccessibility of items that are locked up to prevent theft. Pharmacies, for their part, have complained about shrinking profits for filling prescriptions, citing dramatic declines in reimbursement rates.
In light of these challenges, CVS and Walgreens have looked for profits elsewhere. They've tried to add primary-care clinics, a project that costs a lot of time and money. The chains have also proposed new payout structures for prescriptions, with Walgreens on Tuesday warning that it would be "willing to walk away from a line of business, if it doesn't make sense."
"I'm very confident that over a two- to three-year period we will have reset the framework for reimbursement discussions," Walgreens CEO Wentworth told investors on Tuesday.
He also added that Walgreens is focusing on adding more store-brand products to its chain. That tactic has been successful for Boots in Britain, though it has not done as well in the U.S. so far. Wentworth also said the chain would work to re-hire workers from stores that will close and added that overall, "Many of our actions across this turnaround will take time."
Copyright 2024 NPR | https://www.wemu.org/npr-national-news/2024-10-15/walgreens-will-close-1-200-stores-hoping-for-a-turnaround | 2024-10-15T17:56:57Z |
(MENAFN- PR Newswire)
NEW YORK, Oct. 15, 2024 /PRNewswire/ -
Cordelio Power is pleased to announce the advancement of four development projects into active construction, and one project into full commercial operations, as follows:
Advanced into construction under Full Notice to Proceed:
Crossover is a 135 MW wind project located in Cross County, Arkansas.
Winfield is a 150 MW AC solar project in Lincoln County, Missouri.
Box Canyon is a 300 MW AC solar project in Pinal County, Arizona (50% owned by BrightNight).
McHenry is a 20 MW / 40 MWh battery energy storage system located in McHenry County, Illinois.
Advanced into Commercial Operations:
Moraine Sands is a 165 MW wind project located in Mason County, Illinois.
The company expects all four construction projects to achieved commercial operations by the first half of 2025. All projects (except
McHenry) will deliver their power under 15- or 20-year power purchase agreements.
Approximately $1.3 billion of financings have been completed for the five projects.
"Construction is progressing well across all projects and we are pleased to be working with a strong group of primary contractors including Mortenson, Blattner, Qcells and Pepper Energy to bring these projects through to completion," said Paul Rapp, Cordelio's Chief Operating Officer.
"We're pleased to announce this next wave of projects, as we ramp into our long-term growth goals," said John Carson, Cordelio's Chief Executive Officer. "We're also preparing for the future, with new interconnections filed this year totalling over 6,000 MW of wind projects and 2,500 MW of storage projects, all in the MISO and Pacific northwest power markets. We're excited to continue bringing good business opportunities to all the communities we serve."
About Cordelio Power
Cordelio Power is an independent renewable power producer that develops, owns, and manages renewable power facilities across the United States and Canada. Cordelio strives to work with all of our stakeholders in an efficient, safe, and environmentally responsible manner. With over 1,400 MW of operating assets under management, Cordelio also oversees a growth pipeline of over 20,000 MW of wind, solar and energy storage projects. Cordelio is wholly owned by CPP Investments.
Forward Looking Statements & Information
Certain information contained in this news release constitutes forward-looking information or forward-looking statements (collectively, "forward-looking statements"). All statements other than statements of historical fact are forward‐looking statements. Forward‐looking statements typically contain words such as "anticipate", "believe", "confirms", "continuous", "estimate", "expect", "may", "plan", "project", "should", "will", or similar words suggesting future outcomes, and include, without limitation, all financial projections, estimates of future costs, and projected performance or results. Forward-looking statements by their nature are subject to risks, assumptions and uncertainties which may cause the actual outcomes of such events to differ from Cordelio's expectation as of the date hereof. Whether forward-looking statements ultimately prove to be accurate will depend on factors outside of the control of Cordelio. Readers are encouraged to undertake their own analysis and investigation as to the reasonableness of any such forward-looking statements. Forward-looking statements contained in this news release are made as at the date of this news release and Cordelio disclaims any intent or obligation to update or to revise any of the included forward-looking statements.
SOURCE Cordelio Power
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NEW YORK — (AP) — When Elton John was on tour in America in the 1970s, there was someone on TV who caught his eye. She was an over-the-top, heavy makeup-wearing performer who wore her heart on her sleeve and yet seemed in on the joke — televangelist Tammy Faye Bakker. You could say game was recognizing game.
John — who back then toured in bedazzled hats, cartoonish outfits and sported enough sequins to choke an elephant — was drawn to a woman with caked-on makeup, an ability to connect with fans and the skill to return after a gut-punch of betrayal.
“She fascinated the hell out of me,” John tells The Associated Press. “I love people who come back from the dead, more or less. She was completely outlawed and banished, and she fought through that because of her goodness and kindness and her belief and her faith. It’s an amazing story, Shakespearean in a way."
John has put this Shakespearian heroine's story to song with the stage musical "Tammy Faye" and the latest iteration lands on Broadway this month, championing what he calls "a gladiator on her own terms."
“She comes from absolute nothing — complete poverty — getting all the fame and the wealth and then losing it all in a world of men,” says book writer James Graham. “There is a universality to that story.”
Tammy Faye and Jim Bakker rose to prominence as the husband-and-wife televangelist hosts of TV's Praise the Lord Club from 1974 through 1987. They preached the prosperity gospel, a belief that God wants his followers to be wealthy and healthy.
The Bakkers were embroiled in a scandal when Jim Bakker was accused of sexual assault and financial fraud involving hush money paid to his alleged victim. After divorcing Bakker in 1992, Tammy Faye would go on to marry Roe Messner, who was himself convicted of bankruptcy fraud in 1996.
The musical has been retooled from a run in London in 2022, with two songs out and two added. The project has the blessing of her second husband, and her son Jay Bakker, has attended rehearsals.
The creative team — John, Graham, director Rupert Goold and lyricist Jake Shears of Scissor Sisters — is largely British, except for Shears, so they say they were careful coming to America telling the story of an American icon.
“Most of the music is joyous because it’s set in the South and it’s gospel-orientated,” says John. “I consider her to be joyous and so it was quite easy to write the joyous songs. I love that kind of music. I’m basically a born-again Southern person. It just appealed to me.”
Audiences will see a woman — two-time Olivier Award-winner Katie Brayben reprises her West End Tammy Faye — surrounded by men, including portrayals of Ronald Reagan, Jimmy Swaggart, Pat Robertson and Marvin Gorman.
“She is the one that no one was really paying attention to. Everyone went, ‘Oh, that silly woman with the hair and the eyes.’ She’s the one who’s lasted and now has a musical on Broadway. And I think that’s great,” says Graham.
The musical comes at a time when the culture is reconsidering stories of women lost amid crisis, like Sinéad O'Connor, Janet Jackson and Monica Lewinsky. But the look at Tammy Faye is not entirely sympathetic, pointing out that she turned a blind eye to the vast riches coming into her church.
“We celebrate her values and what she represented and her kookiness and her humor. She got into some stuff as well, though, and we have to hold her accountable for,” says Graham. “We have to test her and push her a bit as well, giving her a prosecution and a defense.”
This is not the first time the story of Tammy Faye Messner, who died of cancer in 2007 at 65, has been explored. RuPaul narrated the documentary "The Eyes of Tammy Faye," which was turned into a Hollywood movie that snagged Jessica Chastain her first Oscar opposite Andrew Garfield.
John has had smashing success on Broadway — like with "The Lion King," "Aida" and "Billy Elliot: The Musical." He sees a few connections between "Billy Elliot" from 2005 with "Tammy Faye." Both lampoon conservatives — Margaret Thatcher in "Billy Elliot" and evangelicals in "Tammy Faye" — and both examine traditional gender roles amid culture wars.
Graham hopes a younger audience can connect even without having lived through the time when Messner warbled gospel songs on TV or cried so much her mascara dripped down her cheeks.
“Way before reality television and cancel culture and social media, in a way, she and her family were the very first reality TV family,” he says. “For a younger audience, it's also all about how you celebrate your individual idiosyncrasies and your identity and not apologize for them.”
In the soulful ballad "Empty Hands" that closes Act 1, Brayben as Tammy Faye sings to her husband: "Here I am/Trying to stand/With faithless mercy/Empty hands/I want to forgive you/ But I don't think I can/With faithless mercy and empty hands."
Messner gained lasting affection for stepping out of the strict evangelical, anti-gay doctrine of the time to show compassion and empathy with Steve Pieters, a gay minister living with HIV and AIDS.
“What she represented even 30 or 40 years ago was a desire to reach across those divides and nothing about her faith contradicted that,” says Graham.
“I think what she represents — that goodness and decency — is something we all, particularly in this election year, need to remind ourselves. We’re not divided by these things. That’s weaponized by people to divide us.”
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.actionnewsjax.com/entertainment/elton-john-turns/OPMRZPSAHRDGTPYBNB4HZQHSFQ/ | 2024-10-15T17:56:58Z |
SAN FRANCISCO — A Navy parachutist was off-target and instead of landing where he should have, he landed on a mother and daughter during San Francisco’s Fleet Week.
The jump happened on Sunday at the city’s Marina Green, the designated target, SFGate reported.
But instead of hitting the spot where the sailor was supposed to land, he fell onto a group of spectators on the area’s perimeter.
The mother and daughter, who were not identified, bore the brunt of the impact but had minor injuries. They were still taken to an area hospital by ambulance, fire department officials said.
The crash was under investigation. It is not known why the jump went bad, KRON reported.
The U.S. Navy released a statement saying, “Our thoughts are with the individual and their family. Safety is our number one priority. We cannot immediately assess what happened; however, we will review this incident to determine the cause,” KRON reported.
© 2024 Cox Media Group | https://www.wftv.com/news/trending/navy-parachutist-lands-mother-child-during-fleet-week-jump/2PYZJGIEO5FAXJOBBX6CXRYMAA/ | 2024-10-15T17:56:59Z |
Staque announces strategic partnership with D-Wave
Staque, a firm in AI, blockchain, and quantum computing, unveiled its partnership with D-Wave Quantum Inc, the world’s first commercial supplier of quantum computers, and launched Que AI autopilots to be powered by quantum computing. This strategic alliance aims to accelerate the adoption of annealing quantum computing solutions across the Middle East, fostering innovation in key industries such as health, logistics, financial services, and technology.
The partnership was announced at Qubits UAE, an exclusive, invitation-only event that gathered top experts in quantum computing and technology leaders. Held under the D-Wave Qubits flagship, the event brought together industry trailblazers to discuss the growing potential of quantum technology in solving complex real-world problems.
“By collaborating with D-Wave, we’re bringing cutting-edge computational processing power to help our clients harness advanced technology for growth,” said Dr. Muhammad Khan, Founder and CEO of Staque. Dr. Khan emphasized how this partnership aligns with Staque’s mission of pushing the boundaries of innovation while creating impactful solutions that drive customer success.
“We believe organizations must embrace advanced technologies such as quantum computing and AI in order to succeed in today’s highly competitive environment,” said Lorenzo Martinelli, chief revenue officer at D-Wave. “Staque recognizes the transformative impact that annealing quantum computing could have on its customers, and our shared commitment to redefining what’s possible with technology makes this partnership very exciting.”
Staque and D-Wave’s partnership comes at a critical time when Middle Eastern nations are looking to diversify their economies. As Dr. Khan highlighted, “The Middle East’s vision of becoming a leader in tech innovation makes our partnership with D-Wave a key milestone. Together, we will help enterprises leverage quantum computing to tackle pressing challenges in optimization, AI, and more.”
Quantum computing presents unmatched capabilities for tackling high-complexity problems, such as supply chain management, utility grid optimization, and portfolio optimization—key areas of focus for both Staque and D-Wave. Utilizing D-Wave’s Leap quantum cloud service, this collaboration aims to develop and deploy hybrid quantum applications, providing regional businesses with access to next-generation computing solutions. One such solution is Que – a network of AI autopilots specializing in various tasks like engineering, customer experience and medical diagnosis. Staque plans on leveraging annealing quantum computing to enhance the machine learning model underlying Que. The first set of Ques (beta) were deployed today for health care and customer service use cases. Ques differ from other AI agents in the sense that they can be continuously trained, hired, leased and monetized through Que Studio and Que Network.
The collaboration is also in line with broader regional goals. Countries like the UAE are keen on expanding their tech and innovation sectors as part of a long-term strategy to reduce dependency on oil-based revenues. According to the International Monetary Fund, economic diversification efforts are central to driving the Middle East’s growth agenda, and partnerships like this one play a crucial role in achieving those objectives.
Staque’s collaboration with D-Wave demonstrates the power of quantum computing, not just in theory but in practical business solutions. From financial institutions to logistics giants, many industries stand to benefit from the incredible computational power quantum technology provides. In addition to the new partnership with D-Wave, Staque is actively building a robust ecosystem of partners across the globe, aiming to integrate AI, blockchain, and quantum computing solutions into everyday business operations. The company’s collaboration with D-Wave symbolizes a larger vision of fostering technological innovation that is both scalable and impactful for businesses across various sectors.
The Qubits UAE event also provided a platform for showcasing various successful use cases of D-Wave’s quantum computing technology. Presentations covered breakthroughs in quantum-fueled AI, business operations optimization, and hybrid quantum computing. These demonstrations further highlighted the real-world impact that these solutions are already having in industries ranging from cybersecurity to material sciences. Moving forward, the companies will focus on scaling their offerings to meet the growing demand for quantum applications in the Middle East and globally. With both D-Wave’s expertise in quantum hardware and software and Staque’s deep knowledge of industry optimization and high-performance computing, the partnership is poised to drive significant advancements in quantum adoption across the region. For further details on the event and the novel work being done by Staque and D-Wave, visit the Staque website or contact Staque directly for more information on partnership opportunities.
Got an interesting story to tell in the UAE? We want to hear all about it. Write to the nation's best reporting team, as we cover the emirates like no one else.
reporters@khaleejtimes.com | https://www.khaleejtimes.com/business/new-venture-seeks-to-boost-quantum-computing-in-the-middle-east | 2024-10-15T17:56:54Z |
Ever since streaming became a thing, I’ve wondered why more people who make TV don’t take advantage of its freedoms.
Sure, creatives talk often about how they’re making 10-hour movies. But that’s frequently just empty bluster to cover for projects which feel like skeletal ideas stretched over too many hours, or a jumble of plotpoints shoehorned uneasily into episodes aimed mostly at boosting engagement.
And then a project comes along like Apple TV+’s Disclaimer. This seven-episode series uses the breadth and sophistication of streaming to tell a tale which evolves steadily, appearing to be one thing before morphing into something else.
In the process, it subverts expectations to ask pointed questions of both the characters and its audience.
A woman who has it all faces her deepest secret
It all begins with Cate Blanchett’s character Catherine Ravenscroft. She’s a journalist and documentary filmmaker successful enough to earn a high-profile award presented by CNN star Christiane Amanpour one moment, and credibly fool a co-worker into thinking Jodie Foster will star in a movie adaptation the next.
She is the sort of high-achieving, work-focused alpha female that Blanchett plays so magnificently – see 2022’s Oscar-nominated Tar – flanked by a well-meaning but feckless husband and an emotionally floundering son.
Living a glamorously upper middle class life, Catherine is a character easy to envy and suspect – so when a novel shows up in her mail which presents a lightly fictionalized story of her extra-marital encounter with a young man decades ago, it’s tough to find sympathy for a woman who seems to have betrayed everyone in her life.
The book, titled The Perfect Stranger, comes prefaced with an ominous, um, disclaimer: “Any resemblance to persons living or dead is not a coincidence.”
The novel paints a picture of horrific self-absorption Catherine is desperate to keep hidden. It details how a woman had an affair with a young man who later drowned trying to save her son, leading the woman to tell police she didn’t know him to cover up their connection.
A journalist renowned for exposing others’ secrets seems to have a terrible one of her own.
A story that moves carefully
It is difficult to explain the many twists this narrative takes without dropping spoilers that will ruin the experience. And some may feel the plot – crafted with an auteur’s flair by writer/director Alfonso Cuarón, based on a 2015 novel by Renee Knight – is too predictable and outlandish to land with the power he so obviously intends.
But I found myself swept away by Cuarón’s patient, attentive style. (You’ll spend way too much time wondering about the inner life of a cat which constantly pops up in Catherine’s home at the oddest moments, framed artfully by the director’s lens.) This is a story that moves carefully in revealing its secrets, but never completes an episode without delivering forward momentum, leaving you with new clues, bigger questions and a desire to learn more.
Cuarón, a Mexican filmmaker whose name is associated with ambitious movies like Gravity and Roma, assembles an ace cast here. Sacha Baron Cohen is convincingly emasculated as Catherine’s entitled husband Robert and Oscar nominee Kodi Smit-McPhee brings maximum emo energy as their drug-addled son, Nicholas.
But it is Kevin Kline who is the revelation, even though he’s turned in Oscar, Emmy and Tony-winning work for decades. An American often cast as the prototypical yank, here Kline expertly plays a quietly caustic British widower – retired private school teacher Stephen Brigstocke, devastated after the loss of his wife.
With an immaculate accent and disheveled style, Kline plays Brigstocke as a man grieving over a family life atomized by loss, stumbling on an ambitious, merciless plan for revenge.
He blames Catherine for the death of his son, which happened after the two met years ago. Brigstocke vows to make her pay, in part, by circulating the book.
Shifting narrators bring different perspectives
Even the narration is complicated here. While Kline's character often reveals his thoughts by speaking directly to the viewer, Catherine’s ideas are rendered by an omniscient female narrator speaking about her, sometimes sounding like the voice of the book itself. (And yes, it can be confusing, possibly on purpose). There are also flashbacks featuring Kline playing Brigstocke as a younger man and a different actress, Leila George, playing the younger version of Catherine.
It all services a tale exploring the power of storytelling and the danger of assumptions leveraged to make us believe.
Yes, the ending is dramatic while spotlighting those ideas in stark terms – some may even find it overly manipulative and a little too pat.
But I reveled in a well-told tale that truly earned every second of its seven-episode length, allowing a master filmmaker the time, talent and resources to weave a story perfectly suited for the streaming space.
Here’s hoping a few other folks working in this industry are paying close attention.
Copyright 2024 NPR | https://www.ideastream.org/2024-10-11/disclaimer-is-a-sprawling-thriller-built-for-the-streaming-age | 2024-10-15T17:57:02Z |
Tami Stackelhouse Celebrates 15 Years of Transformative Health Coaching and Brings #1 Fibromyalgia Podcast to YouTube
Leading Fibromyalgia Wellness Expert Celebrates 15th Anniversary by Bringing Popular Podcast to YouTube
LOS ANGELES, CA, UNITED STATES, October 15, 2024 /EINPresswire.com/ -- Tami Stackelhouse, Master Certified Fibromyalgia Coach® and founder of the International Fibromyalgia Coaching Institute is thrilled to celebrate her 15th Anniversary as a health coach and the 10th Anniversary of her institute, which has been life-changing for fibromyalgia patients worldwide. As part of the celebrations, Tami is excited to announce that she is also bringing her popular show, the ”Fibromyalgia Podcast®”, to YouTube this October, further expanding her reach in educating and empowering those living with this chronic condition.
Stackelhouse says, “I’ve dedicated my life to empowering fibromyalgia patients to take back control of their lives. I believe that with the right support and knowledge, anyone can break free from the limitations imposed by their condition. It’s not just about managing symptoms; it’s about reclaiming joy and purpose in life. You can have a great life, even with fibromyalgia.”
Over the past 15 years, Tami has dedicated herself to helping hundreds of thousands of patients reclaim control of their health and well-being. Her innovative Fibromyalgia Wellness Framework™ has not only guided her own journey from disability to remission but has also transformed the lives of many others.
The longest-running show entirely dedicated to the topic of fibromyalgia, the “Fibromyalgia Podcast®” has amassed over 635,000 downloads and is currently the #1 podcast for fibromyalgia. Tami’s podcast—available via audio on podcasting platforms, including Apple Podcasts and Spotify—continues to be a vital resource, delivering hope and healing to listeners. The upcoming YouTube launch, featuring video interviews, will provide an additional platform for education, sponsorship opportunities, and community engagement.
She says, “The Fibromyalgia Podcast® is a vital platform for sharing stories, strategies, and support. It’s a space where patients can find connection and hope, knowing they’re not alone in their journey. Most importantly, it’s a place to find answers and new ways to feel better. I’m thrilled to bring this message to YouTube, reaching even more individuals needing support.”
As Tami heads into her 10th year since the inception of her first training program, she is focused on empowering future coaches through her Certified Fibromyalgia Coach® and Certified Fibromyalgia Advisor® programs. Graduates of these programs have reported significant improvements in their symptoms after completing their training.
“The need for fibromyalgia-informed coaches is critical,” says Tami. “Many healthcare professionals lack the training necessary to support fibromyalgia patients with effective and efficient treatments. Our trained coaches fill this gap, providing the guidance that patients desperately need.”
Tami aims to raise awareness about fibromyalgia, a condition affecting one in 13 women, and to combat the stigma that often surrounds it. She emphasizes that fibromyalgia is not a psychosomatic illness but a legitimate health concern that requires informed care and support.
She adds, “Education is key to transforming lives. Fibromyalgia affects millions, yet many still go undiagnosed or untreated. By training informed coaches, we create a network of support that not only helps patients manage their symptoms but also fosters a community of understanding and hope.”
Tami invites fibromyalgia patients and aspiring coaches to join her on this journey.
For those looking to improve their lives or seeking to become certified coaches, visit FibromyalgiaCoachingInstitute.com and FibromyalgiaPodcast.com for more information.
Watch the “Fibromyalgia Podcast®” on YouTube at YouTube.com/@fibromyalgiawellness.
About Tami Stackelhouse
Tami Stackelhouse is an award-winning author, founder of the International Fibromyalgia Coaching Institute, and executive producer of the fibromyalgia documentary, “INVISIBLE.” She is passionate about helping fibromyalgia patients break free from the prison their bodies have become, utilizing her signature Fibromyalgia Wellness Framework℠ to inspire hope and transformation.
Heather Burgett
The Burgett Group, Inc.
+1 310-633-4801
email us here
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EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above. | https://www.einpresswire.com/article/750783886/tami-stackelhouse-celebrates-15-years-of-transformative-health-coaching-and-brings-1-fibromyalgia-podcast-to-youtube | 2024-10-15T17:57:02Z |
Dele Alli to France? Champions League side Lille considering move for free agent midfielder who is eyeing England return at 2026 World Cup
Lille are showing an interest in forgotten England star Dele Alli as the midfielder eyes the 2026 World Cup.
Article continues below
Article continues below
Article continues below
- Dele keen to return to club football
- Lille one club interested in midfielder
- Ex-Tottenham star eyeing England comeback | https://www.goal.com/en-za/lists/dele-alli-france-champions-league-lille-free-agent-england-2026-world-cup/bltdbe42f2d0f8dc337 | 2024-10-15T17:57:02Z |
Neterra Welcomes James Knowles as New Chief Product Officer
Date
10/15/2024 9:46:48 AM
(MENAFNEditorial) Neterra, a leading provider of global telecommunication services, is excited to announce the appointment of James Knowles as its new Chief Product Officer. Bringing over two decades of experience in the Telecom and technology industries, James has a proven track record of leadership and product innovation, and will now help drive Neterra's mission to deliver cutting-edge solutions to its global customer base.
James Knowles has held senior leadership roles at prominent organizations, where he developed expertise in Network infrastructure, managed services, and enterprise connectivity. In his new role at Neterra, James will focus on expanding the company’s product portfolio and furthering its position as a leading provider of connectivity, Internet Exchange (IX) services, cloud solutions, and colocation infrastructure.
“I’m thrilled to join Neterra and take on the exciting challenges that lie ahead,” said James Knowles. “Neterra has a long-standing reputation in the industry for delivering high-quality services and a customer-first approach. I’m excited to work alongside this talented team and continue the company’s legacy of innovation and growth.”
Neven Dilkov, Founder and CEO of Neterra, shared his enthusiasm for James joining the leadership team: “We are delighted to welcome James to Neterra. His vast experience in product development and deep understanding of the telecoms market will be invaluable as we continue to innovate and grow. He will be a key member of our C-level team, and I am confident his contributions will accelerate our progress and deliver even greater value to our customers.”
Neterra is committed to expanding its global presence, and with the expertise James brings, the company is set to continue developing solutions that empower businesses with seamless, reliable connectivity.
MENAFN15102024000070016332ID1108780704
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MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780704/Neterra-Welcomes-James-Knowles-as-New-Chief-Product-Officer | 2024-10-15T17:57:04Z |
Now that the threat of Hurricanes Helene and Milton has receded, millions of homeowners and business-owners across Florida and the Southeastern U.S. are faced with traversing the often long and laborious process of using insurance to rebuild their lives.
“You’re just traumatized when you have these losses. At some point, you’re just glad you’re alive,” said Don Hornstein, an insurance law expert at the University of North Carolina. “And then you have to turn to the business side of this. It’s tough.”
Helene was a Category 4 storm that first struck Florida's Gulf Coast on September 26, dumped trillions of gallons of rain and left a trail of destruction for hundreds of miles across several states. At least 246 people have died in what is now the deadliest hurricane to hit the mainland U.S. since Katrina, according to statistics from the National Hurricane Center.
Two weeks later, Hurricane Milton swept across Florida, killing at least 11 people. The Category 3 storm destroyed coastal communities, tore apart homes, filled streets with mud and spawned a barrage of deadly tornadoes.
The combined private insured losses from the two hurricanes could reach $55 billion, according to risk management firm Moody’s RMS.
Immediately after disasters like these, property insurance is likely not top of mind as people secure their safety and basic needs, but insurance claims are part of the process of resetting. Many buy the policies in hope they can help protect them when disaster strikes. But oftentimes insurance doesn't cover what the policy holder thinks it does — or thinks it should.
Rhoda Moehring, who turns 86 this month, says she doesn’t have a lot of faith that insurance companies will help her salvage the flooded rental homes she owns in the river town of Steinhatchee in Florida’s Big Bend.
“I usually get zip with these things,” Moehring said. ”‘Was I insured for that?’ ‘No, sorry, you weren’t.’ And it goes on and on. So I don’t put a whole lot of confidence in it.”
Moehring said she wasn’t sure about the details of her insurance policies and she’ll be relying on her son to help her navigate the claims process.
Here are some steps home and business owners should keep in mind when filing an insurance claim after a natural disaster.
After the immediate emergency response, the first thing a homeowner or business owner should do is call their insurance agent or broker. The deadline to file a claim is generally about 60 days from the date of loss.
There are different types of policies that insure against damage. In the initial call, first focus on thoroughly understanding your policy, including coverage limits, deductibles and exclusions, so that you can do a rough calculation of what is covered and what deductibles are at play to decide if you should file a claim, experts said.
Many policies have payouts in complicated percentage formulas. For example, if your roof is damaged, your policy may spell out different deductibles depending on the roofing material, the age of the roof and even the wind speed from the damage event, and the percentage paid out may be based on the insured value versus the cost of replacement, said Amy Bach, executive director of the consumer advocacy group United Policyholders.
Homeowners should weigh their options, as a minor payout may not be worth the long-term ding on your claims history. That’s especially true if you don’t have flood insurance, as the average home insurance policy covers wind damage but generally doesn’t cover flood damage.
While Helene was primarily a flood event, there may be disputes over what is or isn’t “wind-driven rain” from Milton. Hornstein said the line between wind and water is a thin but very clear line that technical experts can determine. Should there be a proverbial tie, the law favors the insurance company.
“If the house was simultaneously destroyed by flood and, concurrently (by) wind, it’s not covered by private insurance,” Hornstein said.
Business owners should also check to see if they have business income or business interruption insurance, which covers the loss of income and other costs like expenses, salaries, or rent when a business is forced to close.
To file a claim, keep track of and document everything. Before and after photos and videos are ideal to jog your memory of what's been lost and for proof to help bolster settlement claims. For business owners, keeping a record of costs that are incurred after the hurricane is important too.
“You may have evacuation costs, you may have business shut down interruption costs, you may have housing costs, you may have additional expenses that are unusual to your business," said Steve Powell, executive vice president of property and catastrophe for claims management firm Sedgwick.
Once a claim is filed, the insurance company’s adjuster will come to survey the damage, typically within a few days if conditions allow. Be responsive to adjusters and make sure they see (and document) the damage that you see.
While it’s easy to get frustrated, adjusters are likely stressed too, said Lawrence White, an economics professor at the NYU Stern School of Business.
“To the maximum extent possible, try not come across as angry. Try to come across as reasonable,” White said.
If there’s disagreement or concern about the accuracy or fairness of the adjuster’s report from the insurance company, property owners can consider hiring a public adjuster for a second opinion. Their own adjuster can then lead the negotiations with the insurance company. First, however, owners should be aware of the fees the public adjuster charges and check their references.
“The insurance companies have totally the upper hand and when there’s a public adjuster, it does level the playing field a lot for the consumer having someone who speaks insurance and speaks damage," Bach said.
Be aware of the deadlines for accepting a payment offer or filing an appeal with the insurance company.
Once you agree to an insurance payout, know that you can update the claim if more damage is discovered during the repairs though there may be deadlines for how long a homeowner has to reopen a claim.
If the back-and-forth with the insurance company drags on, you may consider hiring an attorney to reach a settlement as a last resort. A dispute that ends up in arbitration could stretch out for a year or more.
About 90% of all insurance claims are settled without escalating into a court fight, said Charles Nyce, a professor of risk management and insurance at Florida State University’s College of Business.
For those with little or no insurance, there are government programs that can assist. The application process is similar to insurance claims: Contact the agency, determine eligibility and file an application.
The Federal Emergency Management Agency offers grants for home repair or replacement for applicants who meet certain conditions. The Department of Housing and Urban Development also offers certain grants that are available for hurricane survivors. And the Small Business Administration offers low-interest loans to renters, homeowners, business owners, and non-profits that suffered losses due to disasters. However, the government has warned that the SBA is running out of money to fund these loans unless its coffers are replenished by Congress.
For more details about these programs visit https://www.disasterassistance.gov.
—-
Associated Press reporter Kate Payne contributed from Tallahassee, Fla.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.actionnewsjax.com/news/after-hurricanes/2HRHM5BXS5AVRB7Z7RKPEQLLR4/ | 2024-10-15T17:57:04Z |
WALTHAM, Mass.--(BUSINESS WIRE)--Innoviva Specialty Therapeutics, Inc., a biotechnology company focused on delivering innovative therapies in critical care and infectious diseases, announced today the presentation of data from three clinical abstracts and two oral presentations on the company’s pipeline and Commercial portfolio during IDWeek 2024, October 16-19, 2024, in Los Angeles, CA.
“Our clinical program continues to provide important findings from recent sub-analyses that add meaningful new insights for healthcare professionals managing difficult-to-treat and antimicrobial-resistant pathogens,” said David Altarac, MD, Chief Medical Officer at Innoviva Specialty Therapeutics. “We are pleased with the progress of our development product zoliflodacin, which recently completed the pivotal phase 3 trial conducted with our partner the Global Antibiotics Research Development Partnership. If approved, zoliflodacin could lead to the first new oral antibiotic to treat gonorrhea in decades.”
IDWeek 2024 Clinical Presentations
- Oral Presentation
Addressing a growing global threat through a novel public-private development partnership
David Altarac, MD, Chief Medical Officer, Innoviva Specialty Therapeutics
Friday, October 18, 2024
8:00 am – 9:00 am PT
Petree C
- Oral Presentation
Activity of Sulbactam-durlobactam and Standard-of-Care Antibiotics against Acinetobacter baumannii-calcoaceticus complex isolates acquired from Hospitalized Patients in the United States (2023 – 2024)
Tomefa E. Asempa, PharmD, Hartford Hospital
Saturday, October 19, 2024
10:54-11:06 am PT
Room 403A
- Poster #P-1103
In Vitro Activity of Zoliflodacin Against Baseline Neisseria gonorrhoeae Isolates from US Participants in a Global Phase 3 Randomized Controlled Trial
Sarah McLeod, PhD, Innoviva Specialty Therapeutics
Friday, October 18, 2024
12:15-1:30 pm PT, Hall J&K
- Poster #P-1251
Pharmacometric Analyses to Support Dose Selection of Zoliflodacin, a First-in-Class Oral Antibiotic Being Developed for the Treatment of Uncomplicated Gonorrhea
Sujata M. Bhavnani, MD, Institute for Clinical Pharmacodynamics
Friday, October 18, 2024
12:15-1:30 pm PT, Hall J&K Time
- Poster# P-1532
Surveillance of Eravacycline Against CLINICAL Pathogens, including Resistant Isolates, Collected Worldwide from Multiple Infection Sites During 2018-2022
Kristie Zappas, PharmD, Innoviva Specialty Therapeutics
Friday, October 18, 2024
12:15-1:30 pm PT, Halls JK
About Innoviva Specialty Therapeutics
Innoviva Specialty Therapeutics, a subsidiary of Innoviva, Inc., is focused on delivering innovative therapies in critical care and infectious disease. Innoviva Specialty Therapeutics’ products, through its affiliate, La Jolla Pharmaceutical Company, include GIAPREZA® (angiotensin II), approved to increase blood pressure in adults with septic or other distributive shock, and XERAVA® (eravacycline) for the treatment of complicated intra-abdominal infections in adults. Innoviva Specialty Therapeutics’ product, through its affiliate, Entasis Therapeutics Inc., include XACDURO® (sulbactam for injection; durlobactam for injection), co-packaged for intravenous use approved for the treatment of adults with hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible strains of Acinetobacter baumannii-calcoaceticus complex (Acinetobacter). For more information about Innoviva Specialty Therapeutics, please visit here.
Contacts
Media Contact:
David Patti
Innoviva Corporate Communications
David.patti@inva.com
908.421.5971 | https://www.biospace.com/news/innoviva-specialty-therapeutics-to-present-new-clinical-data-from-its-development-pipeline-and-broad-commercial-portfolio-at-idweek-2024 | 2024-10-15T17:57:06Z |
A dog — rescued in Tampa by the Florida Highway Patrol after being tied to a fence and left in the rain hours before Hurricane Milton made landfall — is now in foster care, with a new, fitting name.
"His name is Trooper, because of how much he's been through and to honor those who saved him," the Leon County Humane Society in Tallahassee said in a statement.
Trooper was discovered on the side of I-75 in Tampa, according to a video posted by Florida Highway Patrol on Wednesday morning. He was less than 100 miles from where Milton had made landfall.
In the video, which has since amassed over 11 million views, a third of the dog's body appeared submerged in water. There were no signs of his owner returning or how long the dog had been outside.
“It’s OK, it’s OK,” an unidentified state trooper said as he approached the pooch. The dog growled and barked back, to which the state trooper replied "I don't blame you."
FHP Troopers rescued a dog left tied to a pole on I-75 near Bruce B Downs Blvd this morning. Do NOT do this to your pets please… pic.twitter.com/8cZJOfkJL2
— FHP Tampa (@FHPTampa) October 9, 2024
Florida Gov. Ron DeSantis re-posted the video, adding that the state "will hold anyone who mistreats pets accountable."
On Thursday, Leon County Humane Society announced that their dog coordinator got a call from the governor's office about Trooper and picked him up. According to the rescue organization, Trooper was not microchipped.
"We can't imagine the situation that ended with him tied to this pole and left him without any hope," the humane society said. "It's hard even to think about how scared he must have been as cars raced by, the water rose to his belly, and the storm clouds darkened."
The organization described Trooper as "incredibly stressed and still decompressing" but "smiled" on a few occasions.
Since announcing that Trooper was in their care, the rescue group said they have received dozens of inquiries about adoption. But as for now, their main focus is to help the dog feel safe and comfortable in his new environment.
"We have absolutely no idea what his life looked like before he was abandoned," the humane society said. "We want to be sure that we know exactly what he needs before even considering adoption, so he'll be in foster care until we feel confident he's ready for the next phase of life, and that his future will be kind to him."
Milton made landfall around 8:30 p.m. Wednesday near Siesta Key as a Category 3 hurricane. Flooding wreaked havoc throughout western Florida while multiple tornadoes touched down in a retirement community on Florida's east coast.
At least 11 people in Florida have died as a result of Milton. Over 2 million customers remain without power in the state, according to PowerOutage.us.
Copyright 2024 NPR | https://www.ideastream.org/2024-10-11/florida-dog-found-tied-to-fence-and-abandoned-before-milton-is-safe-with-rescue-group | 2024-10-15T17:57:09Z |
AITO, Lebanon — (AP) — An Israeli airstrike on an apartment building in northern Lebanon that killed at least 22 people needs to be independently investigated, the United Nations' human rights office said Tuesday.
“We have real concerns with respect to … the laws of war,” Jeremy Laurence, a spokesperson for the U.N.'s human rights office in Geneva said a day after the strike, as rescue workers searching through the rubble found more bodies and remains. Laurence said the U.N. had received credible reports that a dozen women and children were among the dead.
The Israeli military said it “struck a target belonging to the Hezbollah terrorist organization" and that it would look into reports of civilian deaths.
The apartment building hit in the airstrike was in the small village of Aito, in the country's Christian heartland and far from Hezbollah's main areas of influence in Lebanon's south and east. The strike was a shock to residents, and it exacerbated fears that Israel would expand its offensive deeper into Lebanon.
“I heard a loud noise, like a boom,” said Dany Alwan, who lives next door. “We ran outside, I saw the dust and the smoke and the rubble. There was a body here, another one there. It was a really ugly and painful scene.”
The three-story building had been rented out to the Hijazi family, which fled their home in the southern village of Aitaroun, according to Elie Alwan, Dany Alwan's brother and the building's owner. Some 1.2 million people have fled southern and eastern Lebanon, where the fighting between Israel and Hezbollah has been concentrated.
As rescue workers rummaged through the debris on Tuesday, they found the body of a child, and later a small leg and other remains that they put together in a white bag. The Lebanese military watched as a bulldozer cleared heaps of twisted steel, destroyed olive trees, and crushed rocks.
Over the past year, 2,350 people in Lebanon have been killed in Israeli airstrikes, according to the country's Health Ministry, which says roughly 25 percent have been women and children.
Earlier on Tuesday, the acting leader of Hezbollah said the militant group would fire rockets into more areas of Israel until it ceases its airstrikes and ends its ground invasion of Lebanon.
Naim Kassem said Hezbollah is focused on “hurting the enemy,” comments made in a pre-recorded televised speech delivered on the same day the United States said it sent a small team of troops to Israel to support an American-made missile-defense system.
Hezbollah has fired thousands of rockets into Israel over the past year in support of Hamas' war with Israel in Gaza. Tens of thousands of northern Israelis have been displaced from their homes by those attacks — and Israel has said its war with Hezbollah is aimed at stopping those rockets so families can return home.
On Tuesday, Kassem signaled that Hezbollah would ramp up attacks further south in Israel, which it has already done by targeting Tel Aviv and Haifa. Kassem has headed the militant group since Sept. 27, when its longtime leader, Hassan Nasrallah, was assassinated in an Israeli airstrike.
Hezbollah began targeting Israel with rockets on Oct. 8, 2023, a day after the Hamas attack on Israel that left 1,200 dead and 250 as hostages in Gaza.
Israel's ensuing war against Hamas has left more than 42,000 people dead in Gaza, according to local health officials. They do not differentiate between fighters and civilians, but have said a little more than half the dead are women and children. Hezbollah has insisted it will continue to target Israel until a cease-fire in Gaza is reached.
“We cannot separate Lebanon from Palestine, or Palestine from the world,” Kassem said.
Also on Tuesday, Pentagon press secretary Maj. Gen. Pat Ryder announced the arrival of U.S. troops in Israel on Monday. The team will operate a Terminal High-Altitude Area Defense battery there to defend against ballistic missile attacks from Iran, which backs both Hezbollah and Hamas, and has launched two missile attacks on Israel.
“Over the coming days, additional U.S. military personnel and THAAD battery components will continue to arrive in Israel,” Ryder said.
Iran has warned U.S. troops would be in harm’s way if they launch another attack.
In Lebanon, Israel's bombardment and ground invasion have displaced more than 400,000 children in the past three weeks, according to Ted Chaiban, deputy executive director at UNICEF, the U.N. children's agency.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/news/world/un-says-deadly/WBNC4VJXRJFJTOFBSRUNMBGVW4/ | 2024-10-15T17:57:08Z |
FLAGLER COUNTY, Fla. - — Flagler County suffered an estimated $18.8 million in damages countywide from Hurricane Milton.
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Below is the damages, both costs and debris spread, confirmed by Flagler County:
- Damage Control Estimate = $18.8 M
- Unincorporated = $1.56 M
- Beverly Beach = $1.43 M
- Bunnell = $195,830
- Flagler Beach = $10.95 M
- Marineland = n/a
- Palm Coast = $4.69 M
- Estimated Structural Debris = 145.3 K cubic yards
- Estimated Vegetative Debris = 43.3 K cubic yards
- Property damages:
- 308 affected (<20% of total damages)
- 70 minor (20 - 40%)
- 17 major (40 - 80%)
- 0 destroyed (>80% of total damages)
- 27 inaccessible
With these total damages, FEMA encourages property owners and individuals affected by Milton to register for FEMA assistance by clicking HERE or by calling 800-621-3362. The registration is likely to close around December 10.
FEMA assistance can include the following:
- Displacement Assistance
- Serious Needs Assistance
- Expanded Clean and Sanitize Assistance
- Medical/Dental assistance
- Transportation assistance
- Moving and Storage Assistance
- Misc. Assistance
- Group Flood Insurance Policy
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CNTXT leverages AWS cloud to empower UAE start-up and Abu Dhabi government at GITEX 2024
Date
10/15/2024 9:46:55 AM
(MENAFNEditorial) Abu Dhabi, UAE – CNTXT, a leading data services and solutions company, supported by Amazon Web Services (AWS), an Amazoncompany, embarks on several initiatives to empower Abu Dhabi government as well as UAE startups.
CNTXT aims at developing a unified platform powered by AWS to streamline licensing, permitting, inspection, audit, and litigation processes for the Abu Dhabi government, with the potential to expand to other regions and governmental entities in the UAE. Leveraging UAE-grown LLM models, the initiative will contribute to the development of a robust data and AI service platform for government use. AWS will provide support through access to its technical teams, including Solutions Architects and subject matter experts, helping CNTXT achieve its objectives efficiently and effectively.
CNTXT plan to organize targeted training programs, workshops and technical events on AWS Services and CNTXT technologies to empower UAE startups. With a network of over 120 startups, CNTXT is dedicated to enhancing the capabilities of emerging businesses in the region.
“By combining our strengths, we can collectively accelerate digital transformation adoption in the UAE, ensuring that UAE has the infrastructure they need to succeed,” said Mohammad Abu Sheikh, CEO of CNTXT. “CNTXT’s effort with AWS’s support marks a significant step forward in making the UAE's entire ecosystem future-proof and AI-ready.”
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New real estate platform seeks to provide personalised services
Salman Bin Ali, a leader in Dubai’s real estate, has won the “Best Realtor of the Decade” award.
Bin Ali, who is the CEO of DXBA.com, said: “This award is a reflection of my relentless drive and my commitment to reshaping the real estate industry. From a childhood dream of flying planes to becoming one of the most powerful voices in real estate, my journey has been about breaking barriers, setting new standards, and pushing beyond limits others thought impossible. I have an intimate knowledge of Dubai’s market, and I understand its pulse like no one else.”
Salman’s influence stretches far beyond the boundaries of Dubai. Recognized by Men’s Journal as one of the top entrepreneurs of 2023, Salman has consistently shown an unmatched ability to take on challenges with precision and turn them into extraordinary accomplishments. His awards, including ‘Top Agent in Luxury Homes’ and ‘Best Agent of the Year,’ bear testament to his impact, with billions in sales and properties spanning some of the world’s most prestigious locations—Monaco, France, London.
Salman’s latest venture, DXBA.com is a new platform that aims to rewrite the rules of real estate. Through personalized services and cutting-edge strategies, DXBA.com seeks to deliver a superior client experience.
Got an interesting story to tell in the UAE? We want to hear all about it. Write to the nation's best reporting team, as we cover the emirates like no one else.
reporters@khaleejtimes.com | https://www.khaleejtimes.com/business/salman-bin-ali-receives-best-realtor-of-the-decade-award | 2024-10-15T17:57:08Z |
STEVE INSKEEP, HOST:
We assess the damage from Hurricane Milton in Florida.
MICHEL MARTIN, HOST:
Millions are still without power. At least eight deaths have been attributed to the storm. Five people died when tornadoes touched down in a retirement community in St. Lucie County on Florida's east coast. So this was a serious storm, though not as bad as some feared.
INSKEEP: NPR's Greg Allen went through the storm. He's in St. Petersburg. Hi there, Greg.
GREG ALLEN, BYLINE: Hi, Steve.
INSKEEP: I was watching the forecasts. A storm surge was expected of as much as 15 feet in some places, and at least that didn't happen. Why not?
ALLEN: Well, you know, just a few days ago, Milton was one of the most powerful hurricanes ever seen in the Gulf of Mexico. But as it approached land, it did some things that hurricanes often do - it made this jog. In this case, it was one that took it south of Tampa Bay, which is an area that's really vulnerable to storm surge.
INSKEEP: Yeah.
ALLEN: The hurricane also weakened a bit. But even so, it hit the coast with 125-mile-per-hour winds. But the effect was that the storm surge was much less than it was - than was forecast. It was just 5 to 10 feet above ground level in the area where it made landfall. Tampa Bay, as it turned out, had very little surge. Here's Governor DeSantis.
(SOUNDBITE OF ARCHIVED RECORDING)
RON DESANTIS: You did have storm surge in Sarasota, Venice, Charlotte Harbor and all the way down the west coast of Florida - and some significant storm surge, but not the worst-case scenario of what we were looking at.
ALLEN: Milton did a lot of damage but far less than what was feared.
INSKEEP: Yeah. And I want to pause to respect those who did suffer damage. I know it is serious. I know some lives were lost. But what have you seen around Tampa and St. Pete?
ALLEN: Well, here there are a lot of limbs and trees down, but for the most part, the buildings and other infrastructure held up pretty well against the winds. A construction crane in St. Petersburg toppled into a building, and then the fiberglass roof of the baseball stadium was shredded.
INSKEEP: Yeah.
ALLEN: But homes, on the whole, did pretty well. In St. Petersburg, I talked to Jenna Michael (ph) about what she was seeing in her neighborhood.
JENNA MICHAEL: There's definitely some with trees on their roofs. Like, when we were driving by, we saw some that significantly have damage. But for the most part, it looks like it's mostly downed power lines, downed trees, downed fences and not catastrophic damage to homes.
ALLEN: She had a 50-foot oak tree fall on her property. Thankfully, it missed her house, though.
INSKEEP: I did hear you say, though, yesterday, 19 inches of rain in St. Petersburg, among other places. Can that lead to flooding in days to come?
ALLEN: Right. That's what we're watching for now. A number of rivers across Florida are rising and are expected to flood, and they have been flooding, not just on the coast but also in central Florida. The St. Petersburg area, like you say, got so much rain. In one neighborhood, Melissa Anderson (ph) said she spent the day using towels, blankets, even T-shirts to stop the water from coming into her house.
MELISSA ANDERSON: Water was just coming into the bottom of the house faithfully. It just kept coming and coming and coming until we couldn't stop it anymore - the whole bottom floor. Yeah.
ALLEN: You know, like other people in the neighborhood, her house is not in a flood zone, and she doesn't have flood insurance.
INSKEEP: Greg, thanks so much.
ALLEN: You're welcome. Transcript provided by NPR, Copyright NPR.
NPR transcripts are created on a rush deadline by an NPR contractor. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record. | https://www.ideastream.org/2024-10-11/floridians-are-cleaning-up-after-hurricane-milton-stormed-through-the-panhandle | 2024-10-15T17:57:15Z |
Getty/GOALMitchell Fretton'The FA will contact me' - Harry Kane breaks silence on England's attempts to appoint ex-Bayern boss Thomas Tuchel as new managerH. KaneT. TuchelTransfersEnglandBayern MunichEngland captain Harry Kane has suggested he would approve Thomas Tuchel's appointment as the next Three Lions manager.Article continues belowArticle continues belowArticle continues belowGerman manager new candidate to succeed SouthgateWorked with Kane at Bayern MunichEngland skipper spoke highly of TuchelFollow GOAL on WhatsApp! 🟢📱Article continues below | https://www.goal.com/en-za/lists/harry-kane-breaks-silence-england-bayern-thomas-tuchel-new-manager/blt02bb315a9a4b67d2 | 2024-10-15T17:57:15Z |
WASHINGTON — (AP) — The Biden administration has warned Israel that it must increase the amount of humanitarian aid it is allowing into Gaza within the next 30 days or it could risk losing access to U.S. weapons funding.
Secretary of State Antony Blinken and Defense Secretary Lloyd Austin warned their Israeli counterparts in a letter dated Sunday that the changes must occur. The letter, which restates U.S. policy toward humanitarian aid and arms transfers, was sent amid deteriorating conditions in northern Gaza and reports Israel had conducted a strike on a hospital tent site in central Gaza that killed at least four people and ignited a fire that left more than two dozen with severe burns.
A senior defense official said Tuesday that Blinken and Austin sent a letter to their Israeli counterparts as they saw a recent decrease in assistance reaching Gaza. The official said a similar letter sent by Blinken in April triggered a constructive response and "concrete measures from the Israelis."
The official, who spoke on condition of anonymity to discuss internal deliberations, said the latest letter was a way to similarly address the problem.
For Israel to continue qualifying for foreign military financing, the level of aid getting into Gaza must increase to at least 350 trucks a day, Israel must institute additional humanitarian pauses and provide increased security for humanitarian sites, Austin and Blinken said. They said Israel had 30 days to respond to the requirements.
An Israeli official confirmed a letter had been delivered but did not discuss the contents. That official, speaking on condition of anonymity to discuss a diplomatic matter, confirmed the U.S. had raised "humanitarian concerns" and was putting pressure on Israel to speed up the flow of aid into Gaza.
The letter, which an Axios reporter posted a copy of online, was sent during a period of growing frustration in the administration that despite repeated and increasingly vocal requests to scale back offensive operations, Israel’s bombardment has led to unnecessary civilian deaths and risks plunging the region into a much wider war.
“We are particularly concerned that recent actions by the Israeli government, including halting commercial imports, denying or impeding 90 percent of humanitarian movements” and other restrictions have kept aid from flowing, Blinken and Austin said.
The Biden administration is increasing its calls for its ally and biggest recipient of U.S. military aid to ease the humanitarian crisis in Gaza while assuring that America's support for Israel is unwavering just before the U.S. presidential election in three weeks.
Funding for Israel has long carried weight in U.S. politics, and Biden said this month that "no administration has helped Israel more than I have."
Humanitarian aid groups fear that Israeli leaders may approve a plan to seal off humanitarian aid to northern Gaza in an attempt to starve out Hamas, which could trap hundreds of thousands of Palestinians who are unwilling or unable to leave their homes without food, water, medicine and fuel.
U.N. humanitarian officials said last week that aid entering Gaza is at its lowest level in months. About 80 trucks carrying aid have entered through crossings in Gaza’s north since Oct. 1, down from roughly 60 trucks a day previously, according to the U.N. website tracking deliveries.
COGAT, the Israeli body facilitating aid crossings into Gaza, denied that crossings to the north have been closed.
U.S. officials said the letter was sent to remind Israel of both its obligations under international humanitarian law and of the Biden administration’s legal obligation to ensure that the delivery of American humanitarian assistance should not be hindered, diverted or held up by a recipient of U.S. military aid.
Israel’s retaliatory offensive since the Oct. 7, 2023, attacks by Hamas has killed nearly 42,000 people in Gaza, according to the territory’s Health Ministry, which does not distinguish between civilians and combatants in its count. The Hamas attacks that launched the war killed some 1,200 people, mostly civilians, and militants abducted another 250.
The United States has spent a record total of at least $17.9 billion on military aid to Israel since the war in Gaza began and led to escalating conflict around the Middle East, according to a report for Brown University's Costs of War project.
That aid has enabled Israel to purchase billions of dollars worth of munitions it has used in its operations against Hamas in Gaza and Hezbollah in Lebanon. However many of those strikes also have killed civilians in both areas.
___
AP reporter Josef Federman in Jerusalem contributed.
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/news/world/us-warns-israel/PID4WV563RDD7NYF43L6EUQZBM/ | 2024-10-15T17:57:15Z |
- MAIA seeks to advance two new THIO-derived telomere-targeting molecules to clinical trials
CHICAGO--(BUSINESS WIRE)--MAIA Biotechnology, Inc., (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that an abstract related to the company’s second generation of proprietary telomere-targeting THIO prodrugs has been accepted for poster presentation during the upcoming 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, taking place October 23-25, 2024, in Barcelona, Spain. The Symposium is hosted by the European Organisation for Research and Treatment of Cancer (EORTC), the National Cancer Institute (NCI) and the American Association for Cancer Research (AACR).
MAIA will present the results of preclinical studies for its new THIO-based prodrugs, designated as MAIA-2021-20 and MAIA-2022-12, which are lipid-conjugated compounds derived from THIO. These second-generation compounds belong to a new chemical class of molecules called telomere targeting divalent dinucleotides. These preclinical studies were designed to evaluate the efficacy of the new molecules alone and in combination with or without immune checkpoint-blocking antibodies (anti-PD-L1).
MAIA’s Chief Scientific Officer Sergei Gryaznov, Ph.D. commented, “Our presentation will demonstrate that treatment with each of the prodrugs studied was highly efficacious and was shown to overcome immunotherapy resistance. Our results have shown marked activity in advanced tumors and resulted in tumor growth inhibition in preclinical models of lung cancer, colorectal carcinoma, melanoma and hepatocellular carcinoma. We are actively working to advance these candidates toward clinical development.”
Presentation details:
MAIA has designed and evaluated more than 80 THIO-like compounds to date and has submitted three U.S. patent applications for its second-generation telomere targeting agents.
About THIO
THIO (6-thio-dG or 6-thio-2’-deoxyguanosine) is a first-in-class investigational telomere-targeting agent currently in clinical development to evaluate its activity in Non-Small Cell Lung Cancer (NSCLC). Telomeres, along with the enzyme telomerase, play a fundamental role in the survival of cancer cells and their resistance to current therapies. The modified nucleotide 6-thio-2’-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in profound and persistent tumor regression in advanced, in vivo cancer models by induction of cancer type–specific immune memory. THIO is presently developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors.
About MAIA Biotechnology, Inc.
MAIA is a targeted therapy, immuno-oncology company focused on the development and commercialization of potential first-in-class drugs with novel mechanisms of action that are intended to meaningfully improve and extend the lives of people with cancer. Our lead program is THIO, a potential first-in-class cancer telomere targeting agent in clinical development for the treatment of NSCLC patients with telomerase-positive cancer cells. For more information, please visit www.maiabiotech.com.
Forward Looking Statements
MAIA cautions that all statements, other than statements of historical facts contained in this press release, are forward-looking statements. Forward-looking statements are subject to known and unknown risks, uncertainties, and other factors that may cause our or our industry’s actual results, levels or activity, performance or achievements to be materially different from those anticipated by such statements. The use of words such as “may,” “might,” “will,” “should,” “could,” “expect,” “plan,” “anticipate,” “believe,” “estimate,” “project,” “intend,” “future,” “potential,” or “continue,” and other similar expressions are intended to identify forward looking statements. However, the absence of these words does not mean that statements are not forward-looking. For example, all statements we make regarding (i) the initiation, timing, cost, progress and results of our preclinical and clinical studies and our research and development programs, (ii) our ability to advance product candidates into, and successfully complete, clinical studies, (iii) the timing or likelihood of regulatory filings and approvals, (iv) our ability to develop, manufacture and commercialize our product candidates and to improve the manufacturing process, (v) the rate and degree of market acceptance of our product candidates, (vi) the size and growth potential of the markets for our product candidates and our ability to serve those markets, and (vii) our expectations regarding our ability to obtain and maintain intellectual property protection for our product candidates, are forward looking. All forward-looking statements are based on current estimates, assumptions and expectations by our management that, although we believe to be reasonable, are inherently uncertain. Any forward-looking statement expressing an expectation or belief as to future events is expressed in good faith and believed to be reasonable at the time such forward-looking statement is made. However, these statements are not guarantees of future events and are subject to risks and uncertainties and other factors beyond our control that may cause actual results to differ materially from those expressed in any forward-looking statement. Any forward-looking statement speaks only as of the date on which it was made. We undertake no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law. In this release, unless the context requires otherwise, “MAIA,” “Company,” “we,” “our,” and “us” refers to MAIA Biotechnology, Inc. and its subsidiaries.
Contacts
Investor Relations Contact
+1 (872) 270-3518
ir@maiabiotech.com | https://www.biospace.com/news/maia-biotechnology-announces-poster-presentation-of-novel-thio-prodrugs-at-ena-2024-symposium-on-molecular-targets-and-cancer-therapeutics | 2024-10-15T17:57:16Z |
Transforming Healthcare Access: Heart & Neurology Medical Camp in Zambia on October 26th and 27th
Date
10/15/2024 9:47:13 AM
(MENAFNEditorial) Lusaka, Zambia – Relief is on the way for those facing heart and neurological challenges! Vaidam health is organizing a two-day medical camp at St. Johns Medical Centre in Woodlands, Lusaka, on October 26th and 27th, 2024. This event offers a unique opportunity to receive expert consultations from two highly experienced specialists from India: a senior neurosurgeon and a heart specialist.
About Vaidam Health
As a leading medical tourism company, Vaidam Health bridges the gap between patients and top healthcare providers worldwide. The company’s mission is to ensure personalized care and support for patients throughout their medical journeys. Vaidam Health specializes in connecting individuals with skilled healthcare professionals and state-of-the-art hospitals, bringing specialized treatments directly to communities in need, such as Zambia.
Meet the Specialists
The medical camp will feature consultations from Dr. A. Nagesh and Dr. Venkatesh Yeddula.
1. Dr. A. Nagesh brings extensive expertise in cardiovascular care, emphasizing personalized treatment approaches and the latest innovations for heart health.
2. Dr. Venkatesh Yeddula is an esteemed neurosurgeon, known for his customized treatment strategies and innovative techniques in supporting patients through recovery.
Enhancing Access to Specialized Care in Zambia
Mr. Pankaj Chandna, Co-founder of Vaidam Health, shared, “Through these medical camps, we aim to enhance access to specialized care and address critical health issues in Zambia. This camp marks the sixth consecutive initiative in Zambia since 2022, with a goal of organizing ten camps each year. Our senior heart doctor and neurosurgeon are committed to equipping patients with the knowledge and support necessary to manage their health journeys effectively.”
The medical camp will not only provide expert consultations but also promote cultural exchange, strengthen partnerships, and reinforce Vaidam Health’s commitment to addressing healthcare disparities worldwide. This initiative symbolizes a step forward in creating a healthier global community.
MENAFN15102024000070016800ID1108780707
Legal Disclaimer:
MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780707/Transforming-Healthcare-Access-Heart-Neurology-Medical-Camp-in-Zambia-on-October-26th-and-27th | 2024-10-15T17:57:18Z |
The New York Jets just keep digging the hole deeper.
They put everything into one shot this season with Aaron Rodgers at quarterback. They're 2-4, one of the most disappointing teams in the league. They have fired their coach, Robert Saleh, and in their first game without him they made a month's worth of mistakes and lost a big game to the Buffalo Bills.
If the Jets had won that game, Tuesday's trade for Davante Adams would have made more sense. Now it just seems like they're chasing losses.
The Jets sent a conditional third-round pick that can become a second to the Las Vegas Raiders for Adams. The whole Adams situation isn't the best look for the Raiders either, but we'll come back to that. For now it's the Jets, already all-in, reaching in their pocket to put more chips in the middle but with a bad hand.
There's a scenario in which this all works out for New York. But you have to tell a fairly unbelievable story to get there.
Jets' Davante Adams trade doesn't solve their issues
Adams essentially replaces Mike Williams as the Jets' No. 2 receiver, a few months after the Jets signed Williams to a $10 million deal as part of their veteran shopping spree. In a perfect world Adams is the All-Pro that Aaron Rodgers remembers from his Green Bay Packers days. In reality, he's a 32-year-old receiver whose numbers were way down last season — 1,516 yards and 15.2-yard average in 2022 to 1,144 and 11.1 in 2023 — and is joining a new team in midseason.
By the time Adams gets going in the Jets offense, if he ever does, it might be too late.
Adams could be a big help, giving the Jets a needed secondary option in the passing game after Garrett Wilson (though Allen Lazard has been quite productive) and it could help the Jets take off. But what's the real ceiling for this team?
The Jets are two games behind the Bills now, and the Bills have a road win over New York for tiebreaker purposes. if the Jets don't rally to overtake the Bills in the AFC East, the fight for a wild card spot might not be as tough as first anticipated due to down seasons from the Cincinnati Bengals and Miami Dolphins. Prudently, the Jets would have been better off looking toward what comes next rather than shipping off what might be a top 75 draft pick.
For this to all feel like a success, Adams would have to have a nearly immediate impact, reverse a troubling downward career trend, the 2-4 Jets would have to go about 8-3 to make the playoffs, then in the playoffs they would have to get on a hot streak against division winners who look way better than them right now. Maybe Jets fans would be happy with a playoff appearance and a one-and-done exit. It has been 14 years since they made it at all.
But even for that, the Jets would have to be a different team than they've shown the past six weeks. Adams doesn't fix all the issues with penalties, he won't make the offensive line better and he won't help kicker Greg Zuerlein out of his slump either.
Why didn't the Raiders trade Adams before?
The Raiders side makes more sense. They aren't paying any more of Adams' salary in the trade. That makes the dead cap hits a manageable $13.67 million this year and $15.7 million in 2025 according to Spotrac. It's a significant cap savings for a player that had a $44.1 million cap hit coming next season.
But the whole situation has been odd. The Raiders don't have many stars and Adams was a player who was front and center late last season in getting Antonio Pierce the permanent head coaching job. If the Raiders did want to move away from one of their only marketable stars just two years after a major trade for him, why not do it in March when his value would have been higher? Switching lanes three games into the season, when the Raiders aren't any better or worse than expected, makes it seem like Las Vegas doesn't have a plan. Getting a conditional third for Adams is fine but it's not transformative. At least there's more salary cap room for next season, although probably no enticing quarterback to spend it on.
Maybe it works out for everyone. The Jets make the playoffs with a new-look offense. The Raiders wisely use all that extra salary-cap space next offseason to take a big step in their never-ending rebuild. But at the moment, it's hard to find a clear winner to Tuesday's big trade. | https://www.actionnewsjax.com/news/national/davante-adams-trade/77SOYV6Q5QAIMQGCDXHSND6WWQ/ | 2024-10-15T17:57:18Z |
du and HCT Announce Digitalisation of "OneHCT" Contact Center
Date
10/15/2024 9:47:22 AM
(MENAFN- mslgroup) du, the leading Telecom and digital services provider, today announced a strategic partnership with the Higher Colleges of technology (HCT) to launch the OneHCT project, transforming HCT’s contact center into a digital enhanced hub and developing it in line with the Global Star Rating System for Services. The announcement was made during GITEX Global 2024, where du is showcasing innovations under the theme "Global Collaboration to Forge the Future AI Economy."
The OneHCT project is a comprehensive three-year initiative designed to reimagine and digitally upgrade HCT’s contact center into a fully integrated, multichannel service hub. The scope of work includes integrating the center with HCT’s website and CRM, building an AI-based knowledge database, and launching a pilot phase to ensure smooth operations. The project will see the onboarding of new staff, training to manage over 80 services, and the implementation of advanced technologies such as automated workflows and AI-driven solutions. Continuous improvements will be made through performance analysis, regular training, and the adoption of new automation tools, ensuring that HCT’s contact center consistently meets the highest standards of service excellence.
Dr. Faisal Alayyan, HCT President and CEO, stated that the collaboration with du on the OneHCT project aims to fulfill HCT's vision for institutional digital transformation and to develop a unified and efficient communication platform that encompasses all services for various public segments interacting with HCT, including students, graduates, parents, service providers, and stakeholders. The platform will adhere to new standards ensuring quality and speed while also enhancing follow-up, evaluation, and continuous development based on future needs. He noted that this partnership with du will leverage its expertise in managing call centers and delivering services using the latest technologies, including advanced technology and artificial intelligence.
OneHCT marks a major milestone for HCT, placing the institution at the forefront of digital transformation in education. The project is being delivered in partnership with industry leaders such as Teleperformance and du, bringing top-tier expertise in project management and technology deployment.
Fahad Al Hassawi, CEO of du, said, "We are thrilled to collaborate with HCT on this transformative project. By leveraging our technological expertise, we aim to revolutionise the educational contact center experience, setting new standards for service excellence. This partnership highlights our shared commitment to innovation and delivering exceptional service."
Through OneHCT, HCT's contact center will go beyond traditional operations by adopting new systems and platforms that allow for continuous enhancements. This transformation empowers HCT to independently develop and integrate future innovations, ensuring long-term service excellence.
Mohammed Al Nuaimi, Deputy Director of Shared Services at HCT, explained that the "One HCT" project with "du" is designed to turn the contact center into a fully automated self-service platform, ensuring efficient communication that meets global standards. With over 27,000 students, staff, graduates, parents, and service providers, this shift is a major challenge.
Since the project's start, a contact center was set up in Dubai, following strict quality and security standards. The staff received top-level training to handle various services professionally. The center now operates 24/7 to meet stakeholder needs.
Al Nuaimi added that HCT is using the latest technology to improve the customer experience, making it faster and more efficient. The first phase includes self-services through the contact center and WhatsApp, allowing students to access services without staff. The project continues to evolve with ongoing improvements.
By digitally transforming its contact center, HCT aims to redefine stakeholder engagement and set new benchmarks for service excellence in the educational sector.
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The Stuttgart forward was called off the bench after an injury to club teammate Deniz Undav in the warm-up
Germany's Jamie Leweling celebrates scoring their first goal with Antonio Rudiger against the Netherlands on Monday. — Reuters
A 63-minute rocket from debutant Jamie Leweling gave Germany a 1-0 win over a limp Netherlands in Munich on Monday and a first appearance in the Nations League knockout rounds.
The Stuttgart forward was called off the bench after an injury to club teammate Deniz Undav in the warm-up.
Leweling had an early goal ruled out for the tightest of offsides before blasting in a loose ball from a Joshua Kimmich corner.
A beaming Leweling told Germany's ZDF network "we won as a team, I scored the 1-0, we won 1-0, but we did well and I'm just happy I could help out.
"The Dutch are a top nation, but we played a good game nevertheless. We used the chances that we had well."
Captain Kimmich told reporters the side were proud to overcome a long injury list.
"There were just three players on the field in comparison to five weeks ago against Holland (a 2-2 draw in the Netherlands), that's why we are proud of what we did.
"You could see how happy we are, how proud we are of the performance today.
"We had lots of new players, some young players, unfortunately lots of injuries but you didnt notice much of a difference.
"Jamie had an outstanding debut -- it's not often the Allianz Arena gives you a reception like that -- he did well."
Dutch captain Stefan de Vrij told UEFA "this wasn't the game we wanted. We know Germany have a very strong team. We have to analyse and improve.
"We're confident about our Nations League chances. Next month will be crucial, especially the first game against Hungary, but we will stay positive and try and win those games."
Oliver Baumann, at 34 the oldest debutant goalie in Germany history, pulled off a spectacular save from Donyell Malen in the final minute to protect Germany's victory.
The Netherlands, missing suspended captain Virgil van Dijk, were poor until the dying stages. They stayed second in the group but only on goal difference ahead of Hungary, who beat Bosnia 2-0.
Before the match, the hosts bid farewell to international veterans Manuel Neuer, Thomas Mueller, Ilkay Gundogan and Toni Kroos, who have all stepped down since the home Euros in the summer.
Since starting his reign one year ago to the day with a 3-1 away win over the United States, coach Julian Nagelsmann has been willing to ignore big names in favour of in-form players.
Injuries to key players including Jamal Musiala, Kai Havertz and Marc-Andre Ter Stegen forced Nagelsmann into seven changes, the injury to Undav, who scored both goals in Germany's win over Bosnia on October 11, forced a last-minute reshuffle.
The coach gave Leweling and Oliver Baumann their first caps, while Aleksandar Pavlovic and Angelo Stiller started for the first time.
Leweling appeared to have started his Germany career perfectly when he gave the hosts the lead after just two minutes, but a lengthy video review found Serge Gnabry offside in the build-up.
Despite pressing the Dutch into a series of mistakes playing out from goal, Germany failed to carve another clear opportunity in the first half.
The visitors posed little threat to debutant Baumann's goal, failing to register a shot in the first half.
Leweling's stunning strike jolted the match into life with just under half an hour remaining.
Xavi Simons rattled the crossbar late as the Dutch hinted at a possible comeback, with Malen also going close but failing to break through. | https://www.khaleejtimes.com/sports/leweling-rockets-germany-past-dutch-and-into-nations-league-quarterfinals | 2024-10-15T17:57:19Z |
MANCHESTER, England — (AP) — The rising number of injuries to top soccer players came at a cost of nearly $800 million to teams across Europe's leading leagues last season, according to a report published Tuesday.
At a time when there are growing concerns about the number of games players are being asked to play, the Men’s European Football Injury Index found there were 4,123 injuries in the top divisions of England, Spain, Germany, Italy and France in the 2023-24 campaign.
The cost of the injuries was based on the reported salaries of the players concerned and the amount of time they were sidelined for.
The report highlighted a greater strain on clubs as a result of the newly expanded Club World Cup, which will be staged in America next year.
The number of injuries has risen year-on-year since the index was first published in 2021 and the latest report said "it would be fair to expect a continuation of this upwards trajectory.
“The squad depth of clubs will continue to be tested, particularly with the impending introduction of the new FIFA Men’s Club World Cup in 2025.”
The index is produced by sports insurance firm Howden. Its publication comes a day after a players union and European leagues filed a formal complaint to the European Union against world governing body FIFA.
The 32-team Club World Cup — up from seven — has faced consistent pushback over concerns about player welfare since its new extended format was announced last year.
Last month Man City midfielder Rodri said players were close to going on strike in the face of increased demands on them — including an expanded Champions League this year. The Spain international suffered a season-ending knee injury days after those comments.
The football index has tracked a rise in injuries even before the expanded Club World Cup and Champions League.
It said there had been 14,292 — excluding COVID-19 — in the top five European leagues dating back to the 2020-21 season. That came at a cost of $2.5 billion based on the reported salaries.
Last season alone the figure was $798 million.
On average there was an injury every 92 minutes of football involving teams across those leagues.
It found that German teams suffered the most injuries per game (1.72). German teams also made up the top 13 places in terms of injury susceptibility and accounted for 15 of the top 20.
Of the teams least susceptible to injury, the top four were all from the French league.
The report said there was a “concerning trend” surrounding players under the age of 21, who were sustaining an increase of severe injuries.
___
James Robson is at https://twitter.com/jamesalanrobson
___
AP soccer: https://apnews.com/hub/soccer
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/sports/cost-rising-number/6IFGAUW2Y5FSTKNIM4EKWUKB44/ | 2024-10-15T17:57:22Z |
VB World by Namma Veedu Vasanta Bhavan To Serve a Fusion of Global Cuisine With a Traditional Twist, Plans to Open 25 Outlets
Date
10/15/2024 9:47:29 AM
(MENAFN- Nausheen Shamsher) October 2024, UAE — Namma Veedu Vasanta Bhavan – a renowned South Indian vegetarian restaurant chain with a rich legacy has marked its grand entry into the UAE with the launch of VB World. Founded in 1974 by Shri A.Muthukrishnan Reddy in Chennai, India, the restaurant serves over 30,000 customers daily across their 25 plus outlets in India. This UAE launch, marks the 50th anniversary of the brand, offering the people of the UAE a taste of its celebrated South Indian flavours alongside a diverse range of global cuisines.
The UAE branch, introduced by the Chandramari Group, marks a significant expansion of Namma Veedu Vasanta Bhavan’s legacy. As the founding company of VB World, Chandramari Group with VB World, will continue to showcase their commitment to providing a world-class dining experience that reflects the rich heritage of Vasanta Bhavan while appealing to a global audience.
VB World in the UAE, offers multiple global cuisines with a generous dash of fusion and flair. The menu lists South Indian classics with a twist, Popular Asian dishes with a touch of local flavours and premium North Indian classics. House specialities include a wide variety of Dimsums, authentic woodfired pizzas made to perfection, and a wide choice of popular chaats and Sushi. The soothing, serene ambience and personalised service are designed to let visitors relish each dish.
For dessert and more, there’s Cones and Brews. The artisanal single origin coffee bean, made in close collaboration with some of the best Curers, roasters and coffee estate owners across south of India, perfectly complement the wide range of mouth-watering traditional European desserts, brownies, cakes and savouries. Food aficionados can also surrender to the incredible taste, texture and flavours of their premium softy’s.
“Each product served at VB World reflects laser-sharp focus on freshness, innovation and top-notch quality. Namma Veedu Vasantha Bhavan is already renowned for its quality not just in India, but around the world. VB World is one of our flagship ventures, where we have taken that to another level altogether. We are confident that visitors will relish and savour each distinctive sip, bite and slurp, and keep coming back for more,” says the Group’s Director Anand Krishnan.
VB World marks its first presence in Dubai, UAE, a truly international city which perfectly blends world culture and food together. VB world, Bur Dubai outlet has a seating capacity of over 150 people, and holds a significant milestone in the brand’s international expansion as well. The UAE branch, introduced by the Chandramari Group continues its tradition of excellence while introducing innovative dishes that cater to the cosmopolitan palate
In addition to the UAE, Namma Veedu Vasanta Bhavan operates branches in several countries, including Malaysia, Qatar (Doha, Barwa Village), and the UK (London). This UAE branch adds to the brand’s global network, further solidifying its commitment to delivering high-quality vegetarian cuisine around the world.
The UAE branch, introduced by the Chandramari Group, marks a significant expansion of Namma Veedu Vasanta Bhavan’s legacy. As the founding company of VB World, Chandramari Group has played a pivotal role in bringing this celebrated brand to the UAE, while maintaining its dedication to quality, innovation, and excellence. With VB World, they continue to showcase their commitment to providing a world-class dining experience that reflects the rich heritage of Vasanta Bhavan while appealing to a global audience.
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MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780711/VB-World-by-Namma-Veedu-Vasanta-Bhavan-To-Serve-a-Fusion-of-Global-Cuisine-With-a-Traditional-Twist-Plans-to-Open-25-Outlets | 2024-10-15T17:57:24Z |
Welcome to Week 7, friends! We're officially through (at least) half of the regular fantasy football season which means crunch time for your lineups. Luckily, the scheduling gods offered us a lighter slate of bye weeks this go-around, with just the Dallas Cowboys and Chicago Bears on bye, meaning we should have the bulk of our starting lineups in place ... barring injury, of course.
There are plenty of interesting games on the slate this week, but expect everyone's eyes to be on the showdown between the Kansas City Chiefs and San Francisco 49ers — a matchup of Super Bowls LIV and LVIII, each of them games where MVP QB Patrick Mahomes emerged victorious. Brock Purdy will face Andy Reid's Chiefs coming off a bye — an area where the Chiefs have had success historically — but there's no doubt that the Niners have the better personnel on offense to set their QB up for success.
That's certainly been reflected in their fantasy football value this year, as Purdy has had two games of 24+ fantasy points this year, while Mahomes seeks his first game of more than 18 points through his first five games.
Will Chiefs-49ers be the fantasy-scoring bonanza we all hope it will be? To help you make your lineup decisions, our fantasy experts have ranked their top plays at each position in their Week 7 fantasy football rankings for half-PPR scoring formats:
Good luck with your Week 7 matchups! | https://www.actionnewsjax.com/news/national/fantasy-football/A3725AFWSDNOFJSZYTVOHPSW4I/ | 2024-10-15T17:57:24Z |
‘This prestigious event has a storied history of highlighting emerging talent, and we are excited to support the journey of these promising young golfers,’ says Executive Tournament Director Corkill
Amateur Michael Thorbjornsen, in action at the 2024 HERO Dubai Desert Classic. - Supplied photo
For the fourth consecutive year, the No. 1 player from the PGA Tour University standings at the end of the fall college golf season will earn an exemption into the prestigious Hero Dubai Desert Classic.
This year, the top-ranked player as of November 27, 2024, will secure an invitation to compete in the Rolex Series event at Emirates Golf Club, scheduled for January 16–19, 2025.
In the last two years, the top-ranked PGA Tour University player made the cut at the Hero Dubai Desert Classic. Ludvig Åberg finished tied for 70th in 2023, while
Michael Thorbjornsen secured an impressive tie for 11th in 2024. Both players went on to conclude their collegiate careers ranked No. 1 in the PGA Tour University standings, earning PGA Tour membership.
Åberg continued his success by winning for the first time on both the PGA Tour and the DP World Tour, earning a Ryder Cup captain’s pick in his rookie season. Thorbjornsen posted two top-10 finishes in 10 PGA Tour starts since turning pro in June while Sam Bennett, the first PGA Tour University exemption into the Hero Dubai Desert Classic, finished 31st on the Korn Ferry Tour Points List in his second pro season.
Simon Corkill, Executive Tournament Director of the Dubai Desert Classic, said: “We’re thrilled to once again offer the top-ranked player in PGA Tour University an exemption into the Hero Dubai Desert Classic.
"This event has a rich history of showcasing future stars, and we’re proud to be a part of the journey for these talented young golfers.
“Watching players like Ludvig Åberg and Michael Thorbjornsen not only compete but excel on the global stage reinforces the significance of this opportunity,” he added. “We look forward to welcoming the next top-ranked player to Emirates Golf Club and seeing what they can achieve in this prestigious Rolex Series event.”
Auburn’s Brendan Valdes is currently No. 1 in the PGA Tour University Ranking, and he narrowly leads North Carolina’s David Ford. Also in contention for the exemption are Arizona State teammates Josele Ballester (No. 3), who won the U.S. Amateur earlierthis summer, and Preston Summerhays (No. 4).
The No. 1 player in the PGA Tour University Ranking on November 27 th, 2024, will not only receive the exemption into the Hero Dubai Desert Classic, but also the full PGA Tour University points for his finish in the event.
Brendan von Doehren, Executive Director of PGA Tour University, said: “The Hero Dubai Desert Classic has played an integral role in the careers of Sam Bennett, Ludvig Åberg and Michael Thorbjornsen, and we couldn’t be more thankful for the tournament’s support of PGA Tour University and amateur golf.
"There’s no better way to prepare for a professional career than competing against the world’s best in an event like the Hero Dubai Desert Classic”
ALSO READ | https://www.khaleejtimes.com/sports/pga-tour-universitys-leading-player-to-earn-an-exemption-for-2025-hero-dubai-desert-classic-for-fou | 2024-10-15T17:57:26Z |
Carnival Corporation (CCL) has rallied more than 60% in the past year, accompanying the stunning returns recorded by its industry peers over this time frame. Similar to other cruise stocks, Carnival’s rally has been driven by the company’s return to profitability and robust demand for cruise vacations. As we reach a few years into the recovery, investors may wonder if there is more room for growth on a seemingly attractive valuation. Others may question whether the daunting debt load will limit future upside. I lean toward the latter view.
While shares appear to trade at an attractive valuation, Carnival’s substantial debt levels, made necessary by pandemic-induced losses, hinder CCL stock’s long-term potential from here, in my view. I have a neutral sentiment on CCL at this time.
A Strong Turnaround From Losses to Profitability
Carnival’s path to recovery has been nothing short of remarkable. It was very interesting to observe that the company has been consistently profitable, with the exception of the COVID-19 pandemic. Otherwise, results have been in the black even during challenging periods like the 2008-2009 financial crisis. Carnival had never incurred an annual loss until the COVID-19 pandemic hit. The return to profitability has also ben impressive, but I’m cautious on the shares.
During the pandemic, Carnival had to adapt to the troubling reality of travel restrictions and weak consumer demand. The company’s entire fleet was grounded, and its financials suffered immensely. Between 2020 and 2022, Carnival incurred billions of dollars in losses, marking the most difficult period in its history. However, as global travel resumed, the cruise giant began to turn things around, with its two most recent quarters showing profits, including Q2. Those who know the cruise industry will understand that the third-quarter (the summer quarter) represents pinnacle performance for the year.
Debt Issuance and Business Recovery
While the recent return to profitability is encouraging, it’s necessary to mention that Carnival’s ability to survive the pandemic was mainly due to its ability to raise cash. The company raised over $19 billion in capital during these years, primarily through debt issuance, to cover its cash burn during the long operating hiatus. This massive influx of cash allowed Carnival to maintain liquidity, repatriate guests, and keep its fleet operational while preparing for the eventual recovery.
Fortunately, Carnival’s strategy proved successful. As industry conditions stabilized, its revenues and profits began to rebound rapidly. This trend has been well-sustained, evident from its most recent fiscal Q3 earnings report. Carnival posted a net income of $1.7 billion, up by over 60% compared to the previous year, on record revenues of $7.9 billion. These numbers were driven by pent-up demand for cruises and Carnival’s efforts to increase ticket prices and onboard spending. Carnival forecasts that its full-year 2024 adjusted EBITDA will exceed $6 billion, even surpassing its pre-pandemic levels!
Debt Overhang and Potential Upside
Despite Carnival’s impressive turnaround and record-breaking revenue and EBITDA projections, I believe that its substantial debt load is alarming. At the end of June, Carnival had net debt outstanding of $28.8 billion. While the company is generating record revenues, and Wall Street expects free cash flow of $2.7 billion this year, growing to $3.43 billion next year, it will take years of disciplined deleveraging to bring its debt back to safer levels. This is why I assign a neutral rating for CCL.
In terms of valuation, the stock may still appear attractive to many. Carnival currently trades at just 15.4x this year’s expected earnings and 12.1x next year’s estimate. That would seem to indicate room for further potential upside. However, I believe the company’s heavy debt load casts a long shadow over this potential. While the company’s strong earnings recovery might initially make the stock seem undervalued, much of Carnival’s future cash flow will likely be deployed toward debt repayment, leaving little to no room for reinvestment or returns to shareholders. CCL stock currently offers no dividend.
Is Carnival Stock a Buy, According to Analysts?
Looking at Wall Street, TipRanks classifies Carnival stock as Strong Buy despite its prolonged rally. This is based on 14 Buy ratings, two Hold ratings, and one Sell rating assigned in the past three months. At $23.90, the average CCL stock price target implies nearly 20% potential upside.
If you’re unsure which analyst to follow when trading CCL stock, consider Brandt Montour from Barclays (BCS). Over the past year, Brandt has been the most accurate and most profitable analyst on CCL, delivering an average return of 37.19% per rating with a 86% success rate.
Investment Takeaway
Overall, while Carnival has mounted an impressive recovery thanks to a return to profitability amid surging demand for its cruises, I believe the company’s heavy debt burden remains a notable challenge. CCL stock’s valuation may appear attractive, given near-term EPS projections, but its long-term upside is likely to be limited by the need to prioritize debt reduction. With much of its future cash flow likely deployed toward deleveraging, Carnival’s ability to invest in growth or return of capital to shareholders may be constrained, making any further potential for gains less certain in the years ahead.
My rating on CCL stock is neutral.
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. | https://www.nasdaq.com/articles/62-past-year-can-carnival-stock-ccl-produce-further-gains | 2024-10-15T17:57:26Z |
First-in-Human Data from Phase 1 Trial of MZE829 Support Advancement to Phase 2; Phase 2 Trial Expected to Initiate Early 2025
Preclinical Data for MZE782 Support Recent Phase 1 Trial Initiation in Healthy Volunteers
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Maze Therapeutics, a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with common diseases, today announced that upcoming presentations at the American Society of Nephrology’s (ASN) Kidney Week, being held October 23-27, 2024, in San Diego, and the American Society of Human Genetics Annual Meeting, being held November 5-9, 2024, in Denver, will highlight the company’s two lead clinical programs to treat kidney disease. Data from the company’s Phase 1 trial of MZE829 for the treatment of APOL1-mediated kidney disease will be presented at ASN Kidney Week 2024, and new preclinical data supporting the potential of its second lead program, MZE782, a potentially first-in-class, oral, small molecule targeting the solute transporter, SLC6A19, will be presented at ASN Kidney Week 2024 as well as at the American Society of Human Genetics Annual Meeting.
“We look forward to presenting new, positive data for our two lead programs, MZE829 and MZE782, both of which have the potential to address severely underserved patients living with kidney disease,” said Harold Bernstein, M.D., Ph.D., president, R&D, and chief medical officer of Maze. “Importantly, the Phase 1 data from our study of MZE829 in healthy volunteers support this program’s advancement into our planned Phase 2 trial in patients, which we expect to initiate in the coming months. In addition, the preclinical data we’ll present from our MZE782 program formed the basis of our investigational new drug application and recently initiated Phase 1 trial in healthy volunteers. We are pleased by the progress we continue to make at Maze and excited to learn more about the potential of these programs, generated through novel insights from our Compass platform, as they progress through the clinic.”
Details of the presentations are as follows:
American Society of Nephrology Presentation Information
Title: A Phase 1 Study in Healthy Adults of the Safety, Tolerability, and Pharmacokinetics of MZE829, an APOL1 Inhibitor for the Treatment of APOL1-Mediated Kidney Disease (AMKD)
Date & Time: October 24, 2024, 10 a.m. – 12 p.m. PT
Presenter: Susan Limb, M.D., Ph.D.
Title: SLC6A19 (BOAT1) allelic series: loss of function is associated with improved kidney function
Date & Time: October 24, 2024, 10 a.m. – 12 p.m. PT
Presenter: Rob Graham, Ph.D.
Title: Genetic ablation of SLC6A19 is protective against renal damage in mouse models of chronic kidney disease
Date & Time: October 26, 2024, 10 a.m. – 12 p.m. PT
Presenter: Laura Sanman, Ph.D.
American Society of Human Genetics Presentation Information
Title: Functional characterization of Hartnup’s disease missense variants in SLC6A19 shows loss of function by disparate mechanisms
Date & Time: November 6, 2024, 2:30 – 4:30 p.m. MT
Presenter: Nathan Sallee, Ph.D.
Title: SLC6A19 loss of function is associated with improved kidney function and metabolic reprogramming of kidney cells
Date & Time: November 9, 2024, 8:45 a.m. MT
Presenter: Sahar Mozzafarri, Ph.D.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with common diseases, with a focus on renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which provides insights into the genetic variants in disease and links them with the biological pathways that drive disease in specific patient groups. The company’s pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. For more information, please visit mazetx.com, or follow us on LinkedIn and X (formerly Twitter).
Contacts
Jillian Connell, Maze Therapeutics
jconnell@mazetx.com
(650) 850-5080
Media:
Dan Budwick, 1AB
dan@1abmedia.com | https://www.biospace.com/news/maze-therapeutics-to-present-new-data-supporting-advancement-of-mze829-and-mze782-clinical-development-at-american-society-of-nephrologys-kidney-week-and-american-society-of-human-genetics-annual-meeting | 2024-10-15T17:57:26Z |
Kylian Mbappe edited out of Real Madrid promotional image in latest drama concerning controversial France forward
Real Madrid airbrushed Kylian Mbappe out of photos promoting their latest clothing range as controversy around the forward grows.
Article continues below
Article continues below
Article continues below
- Real Madrid promoting new clothing line
- Mbappe part of original cast
- Later removed in final cut of promo | https://www.goal.com/en-za/lists/kylian-mbappe-real-madrid-promotional-image-controversial-france-forward/blt12a28d12e1dd4dfb | 2024-10-15T17:57:28Z |
Haason Reddick has been given permission to seek a trade, New York Jets owner Woody Johnson said at the NFL's fall meetings in Atlanta on Tuesday.
Reddick has not played this season while in a contract dispute with the Jets, who acquired him from Philadelphia in late March to boost their pass rusher. Instead, the star edge rusher has not been with the Jets since his trade was finalized and he passed his physical on April 1.
Drew Rosenhaus, who along with Ryan Matha now represents Reddick after the player recently switched agents, said Monday he was looking forward to getting the issues resolved as soon as possible. Rosenhaus attended New York's 23-20 loss to Buffalo on Monday night, presumably in part to meet with Jets officials.
“He would like to be a New York Jet for years to come,” Rosenhaus said hours before the game, "and our goal is to make that happen.”
Apparently, Reddick would really like to play elsewhere. When asked if the Jets had given him permission to look for a trade, Johnson said simply: "Yes."
During a conference call last Tuesday to discuss the firing of coach Robert Saleh, Johnson made a direct plea to Reddick to join the team.
The 30-year-old Reddick requested to be traded on Aug. 12, but general manager Joe Douglas quickly nixed that, saying New York would not grant his wish to be dealt. But it now appears it is heading that way, after all.
And it comes on the heels of the Jets agreeing to terms Tuesday, according to two people with knowledge of the situation, to acquire wide receiver Davante Adams from Las Vegas — reuniting him with quarterback Aaron Rodgers.
Reddick was placed on the reserve/did not report list on July 25, the second day of the team's training camp practice.
Reddick accumulated around $5 million in fines for not attending mandatory workouts and training camp. He also is forfeiting a game check for each one he misses, which is an additional loss of nearly $5 million.
The Jets could explore their options with teams seeking pass rushing help, perhaps such as the Detroit Lions, who will be without star Aidan Hutchinson after he was lost for the season with a broken tibia and fibula.
Reddick was scheduled to make $14.25 million in nonguaranteed base salary in the final year of his contract, but he wanted a long-term extension from Philadelphia. When the Eagles declined to give him a new deal, Reddick asked for a trade and ended up in New York.
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AP Pro Football Writer Rob Maaddi in Atlanta contributed to this report.
___
AP NFL: https://apnews.com/hub/nfl
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/sports/jets-are-giving/QRYIFRCHAZH6JGDLZ4HBJPOIYA/ | 2024-10-15T17:57:29Z |
Over 500 Children Explore Careers with "Little Employee" Initiative
Date
10/15/2024 9:48:03 AM
(MENAFN- qf) 14 October 2024 - Doha, Qatar - As the fourth edition of the 'Little Employee' initiative continues, Qatar Career Development Center (QCDC), founded by Qatar Foundation (QF), celebrates the program's midway achievements, marked by the participation of over 500 children alongside several leading entities in Qatar.
Launched in May and running through December 2024, the initiative offers children aged 7-15 the opportunity to explore their parents’ workplaces, gaining real-world, firsthand insights into diverse careers.
The list of key participating organizations in the fourth edition of the initiative so far includes several ministries and entities from both the public and private sectors, such as the Ministry of Education and Higher Education, the Ministry of Defense, the Ministry of Interior, the Ministry of Environment and Climate Change, the Ministry of Commerce and Industry, Qatar Foundation, the General Tax Authority, the General Retirement and Social Insurance Authority, Qatar News Agency, Qatar Airways, QatarEnergy LNG, Qatar Museums, Doha and Al Rayyan Municipalities, Hamad General Hospital, Wifaq Family Counseling Center, and START Trading and Services. These organizations demonstrate strong involvement from across various sectors, both public and private.
Reflecting on the initiative’s success, Saad Abdullah Al-Kharji, Acting Director of QCDC, said: "We are proud of the progress achieved by the 'Little Employee' initiative so far. We see the upcoming phase as a valuable opportunity to strengthen and expand our strategic partnerships with key institutions across a range of sectors at the national level.”
“We encourage companies and families to invest in this next stage, empowering children to gain practical experiences that will enrich their understanding of the world of work. This will ultimately contribute to developing a generation that is informed, prepared, and equipped for future challenges and career paths,” Al-Kharji added.
With schools nationwide preparing for the October mid-term break, QCDC invites more companies, parents, and students to participate in the initiative. The break provides an ideal opportunity for families and organizations to engage in the 'Little Employee' initiative, as children are free from school obligations and often seek new ways to spend their time. This makes it convenient to offer their children an educational and entertaining behind-the-scenes experience at their parents' workplaces while helping instill early-age career awareness and culture.
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MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780715/Over-500-Children-Explore-Careers-with-Little-Employee-Initiative | 2024-10-15T17:57:31Z |
The dominant performance at Dambulla was Sri Lanka's sixth-largest T20 win against any team, surpassing their previous best over West Indies — a 57-run triumph in London in 2009
A Sri Lankan fan takes selfies with Sri Lanka's Dunith Wellalage (2nd R) and Matheesha Pathirana (R) after Sri Lanka won by 73 runs during the second Twenty20 international cricket match between Sri Lanka and West Indies at the Rangiri Dambulla International Stadium in Dambulla on Tuesday. — AFP
Sri Lanka stormed back to level the three-match T20 series with an emphatic 73-run win over the West Indies on Tuesday, marking their largest ever margin of victory against the Caribbean side.
The dominant performance at Dambulla was Sri Lanka's sixth-largest T20 win against any team, surpassing their previous best over West Indies — a 57-run triumph in London in 2009.
Sri Lanka, after setting a competitive target of 163, unleashed a relentless assault from their spinners, skittling the visitors for just 89 runs in 16.1 overs.
This score marked the West Indies' lowest total against Sri Lanka in T20 internationals, and their sixth lowest ever.
The spin-dominated attack claimed nine wickets, with only three overs of pace bowled, capitalising on a worn pitch that deteriorated quickly, leaving West Indies with no foothold in the chase.
Sri Lanka's spin magic struck early, removing both openers within the first four overs.
Evin Lewis and Brandon King, who had been the architects of West Indies' explosive start in the first match with a 107-run partnership, were neutralised by Sri Lanka's bowlers.
Debutant all-rounder Dunith Wellalage made an immediate impact, dismissing King with a sharp stumping in his first over, while almost sending Lewis packing on his first ball — though a missed review kept Lewis briefly in play.
Wellalage struck again, claiming Roston Chase at slip, as the West Indies stumbled to 17-3, and struggled to 21-3 by the end of the power play.
Wellalage's stunning debut saw him finish with figures of 3-9 in four overs.
Sri Lankan captain Charith Asalanka called it a "very pleasing win", and hailed Wellalage's performance as "sensational".
Maheesh Theekshana, Charith Asalanka and Wanindu Hasaranga supported Wellalage's efforts with two wickets each, cementing Sri Lanka's grip on the game.
Sri Lanka's total of 162 was built on the solid foundation set by openers Kusal Mendis and Pathum Nissanka, who combined for a 72-run stand.
Nissanka top-scored with 54 off 49 balls, peppering the boundary with nine fours and a six.
"It was a tough wicket to bat on," Nissanka said. "I took some calculated risks — we had a target of 160 and were glad we got there."
Contributions from Kusal Perera (24) and Kamindu Mendis (19) helped push the total past 160, setting up a challenging chase for the West Indies.
On the visitors' side, spinners Chase and Gudakesh Motie were economical, giving away only 37 runs in their combined eight overs, raising questions about the West Indies' decision not to include an additional spinner.
The stage is now set for a thrilling series decider on Thursday, also at Dambulla, with eighth-ranked Sri Lanka eyeing an upset series victory over the third-ranked West Indies.
West Indies skipper Rovman Powell credited Sri Lanka for using "the conditions well" and acknowledged that his men "didn't bat well".
But he said the team would look ahead to the series decider.
"We will look back at things and reassess things and bounce back", he said.
The West Indies won the first match after a commanding five-wicket victory on Sunday. The T20 series will be followed by a three-match ODI series. | https://www.khaleejtimes.com/sports/sri-lanka-level-t20-series-with-record-breaking-west-indies-win | 2024-10-15T17:57:32Z |
The following is an excerpt from the latest edition of Yahoo's fantasy football newsletter, Get to the Points! If you like what you see, you can subscribe for free here.
Fantasy managers will spend the next 24 hours working the waiver wire, but that's obviously just part of the process. In most instances, you also have to make a corresponding drop. And we'd like to help you make those difficult cuts.
Most fantasy advice will never be one size fits all, and that's especially true for a cut list. You need to apply this to your situation and the context of your league. A nifty stash in one league could be a see-you-later player in a different room. And remember, if you never make a regretful cut during the season, you're probably playing far too conservatively.
Isaiah Likely, TE, Ravens (59% rostered)
I have a few fantasy shares of Likely, and I'm not eager to give them up. But we have to accept that he's merely a contingency-value stash at tight end these days, not someone you can play. He has just nine catches since the blowup season opener. Unless Mark Andrews gets hurt, Likely can't be trusted in lineups. And in the teeth of bye season, that might make him a drop now.
Dontayvion Wicks, WR, Packers (47% rostered)
You used good process when you added Wicks, but he didn't come through in his last two opportunities, and now the receiving room is healing up. The Packers also have two talented backs and a tight end of note. Wicks is also dealing with a shoulder injury, giving him week-to-week status. In most formats, it's not worth the wait.
Trey Sermon, RB, Colts (48% rostered)
Jonathan Taylor probably isn't long off, even if he can't play in Week 7. But Sermon has a more immediate issue — Tyler Goodson is clearly outplaying him. Surely this isn't lost on the Indianapolis coaching staff.
Antonio Gibson, RB, Patriots (49% rostered)
He flopped in his starting opportunity last week (13 carries, 19 yards) and the Patriots will go back to Rhamondre Stevenson when healthy, no matter how much he fumbles. And some of New England's rushing production will also be distributed to athletic and resourceful rookie QB Drake Maye.
Jerome Ford, RB, Browns (73% rostered)
He's dealing with a balky hamstring, the offense is shipwrecked by poor blocking and QB play, and Nick Chubb might return this week. Ford was a fantasy dud most of the year, and while much of it wasn't his fault, he has a capped ceiling.
Daniel Jones, QB, Giants (21% rostered)
He made sense as a Week 6 sleeper, even though his home/road splits are starting to become too large to ignore (Jones, for some reason, plays poorly in New Jersey). It's a home date against Philly this week, and then a trip to Pittsburgh. Even with Malik Nabers expected back, we hope you have a better QB option to navigate the bye weeks. | https://www.actionnewsjax.com/news/national/fantasy-football/FC4M6YSYJ5WC6BJCO3H3DEJPM4/ | 2024-10-15T17:57:31Z |
Zone·ify Expands FAST Channel Lineup With 5-Minute Crafts® and 123 Go
The app will offer content from TheSoul Publishing with 180M+ cross-platform subscribers
Our partnership with TheSoul Publishing is another example of our commitment in curating the finest content on our fast-growing free streaming TV service in North America.”
TOLEDO, OH, UNITED STATES, October 15, 2024 /EINPresswire.com/ -- Zone·tv today announced that its premier Free, Ad-Supported Television (FAST) app zone·ify will now feature 5-Minute Crafts® and 123 Go!, two of TheSoul Publishing’s most popular brands. 5-Minute Crafts® is the most-watched DIY digital brand in the world with more than 400 million social media subscribers. 123 Go! brings lighthearted teen content to hundreds of millions of viewers worldwide. — said Doug Edwards, President of Zone·tv
“TheSoul Publishing’s content brings a zest for life to zone·ify viewers,” said Doug Edwards, President of Zone·tv. “Their fun and trendy content adds even more depth to the myriad content that zone·ify users already enjoy.”
“Zone·ify is a perfect platform for the 5-Minute Crafts® and 123 Go! audiences,” said Jonathan Shrank, TheSoul Publishing’s Director of Distribution and Streaming Content Partnerships. “The fully customizable app means that viewers will have a new amazing way to find, watch, and share our shows with their families and friends.”
Zone·ify users can access all of the content on the zone·ify home screen and program guide, today.
“Zone·ify has become known for delivering breadth and depth of content for our audiences,” added Edwards. “Our partnership with TheSoul Publishing is another example of our commitment in curating the finest content on our fast-growing free streaming TV service in North America.”
About zone·tv™
Zone·tv bridges the gap between technology and engaging programming with its innovative technology solution offering a best-in-class, convenient and highly personalized viewer experience. The zone·tv™ Studio suite of tools allows any video service provider to create personalized thematic channels with their own content. Zone·tv uses its own zone·tv Studio tools to create the zone·ify multi-channel video service – an unprecedented linear-like viewing experience, powered by A.I. Its proprietary software architecture combined with an 8,000+ hour content library has powered the company’s monumental growth.
Its diverse programming can be seen on cable TV, Mobile, Web and connected devices including, Comcast Xfinity, U-Verse, Cox Contour box, XUMO box, Rogers Ignite TV, Videotron, iOS Mobile, Android Mobile, FireTV, Roku, AndroidTV, and others.
The company has offices in Toronto, Canada, and Northwood, Ohio
Get zone·ify directly on the App Stores or online at www.zoneify.tv
About TheSoul Publishing
TheSoul Publishing is the world’s leading digital studio that produces engaging, positive, and original content for a global audience. With a creative team based in more than 70 countries and six continents, TheSoul Publishing showcases entertaining brands in 21 languages, which are distributed through a social media-driven cross-platform network.
TheSoul Publishing’s award-winning portfolio offers a wide range of enjoyable content, including cutting-edge 3D technology, stop-motion production, live-action videos, music, craft projects, and vibrant animation, across its universe of well-known channels, including the world’s number one DIY brand, 5-Minute Crafts®, Bright Side, 123 GO!,
Avocado Couple, La La Life, Teen-Z, Baby Zoo, Slick Slime Sam, and Polar.
Founded in 2016, TheSoul Publishing is headquartered in Cyprus with production studios and offices in Europe and the U.S. For more information, please visit https://www.thesoul-publishing.com/
All zone·tv press inquiries should be directed to:
—
Zone·tv Media Relations
Arika Najafi
Zone.tv LLC
mediarelations@zone.tv
Legal Disclaimer:
EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above. | https://www.einpresswire.com/article/750802139/zone-ify-expands-fast-channel-lineup-with-5-minute-crafts-and-123-go | 2024-10-15T17:57:33Z |
GUADALAJARA, Mexico -- As he sits fiddling with the strings on his hoodie in the Guadalajara sun, Malik Tillman's voice hardly rises. He's calm, as he always is. The 22-year-old midfielder rarely shows emotion. No matter the situation, Tillman remains stoic, reserved and, to be honest, just a little bit shy.
His voice may not rise often but, for a split second, a burst of passion comes out. That's because he has a confession to make: he knows what people think of him.
Tillman is naturally quiet, but he has become very aware of what his shyness portrays. He knows how it's perceived when he doesn't bat an eye, yell or react when things don't go his way or, more importantly, his team's way. He knows that there's a segment of U.S. men's national team fans that see him walking off the field emotionless and wonder one thing: why doesn't he feel this as much as we do?
From the outside, it may look like he doesn't care. Tillman sees that, feels that and understands that, but he's also determined to set the record straight.
Malik Tillman does, in fact, care, perhaps more than even those closest to him realize.
"Some people say I'm not interested in the game just from the way I look," Tillman tells GOAL, "but it really is more or less the other way around. That's just how I express myself. I'm a chill guy, and that's also me on the pitch. I might seem relaxed or seem like I don't care, but it really is the other way around.
"I mean, this is just how I am. This? This is how I can be the best I can be."
Tillman is reaching a point where the USMNT will need him to be at his best. With new coach Mauricio Pochettino leading the charge, there are big expectations now being placed on Tillman's shoulders, including from the coach himself. On the club level with PSV, Tillman is the best he's ever been. He's third in the Eredivisie with four goals and he leads the Dutch league in chances created with 21. The goal of being at the 2026 World Cup is in sight, particularly if he continues on the path he's currently on.
Tillman doesn't talk about his goals much. In fact, he doesn't talk about anything much. He generally keeps to himself, both on the field and off of it. Don't mistake his shyness for meekness, though. As he looks to make his mark and seize opportunities for club and country, he has one more message to send:
"As soon as the game comes, for me, I'm not afraid of anyone," he insists. | https://www.goal.com/en-za/lists/malik-tillman-exclusive-usmnt-psv/blt3dd14c83b42c4cf1 | 2024-10-15T17:57:35Z |
CHARLOTTE, N.C. — (AP) — Joey Logano hoped he'd done enough to advance in NASCAR's playoffs with an eighth-place finish at Charlotte Motor Speedway.
But when he left the track Sunday night, he was four points below the cutline and eliminated from any shot at winning a third Cup Series title.
Then came the phone calls: inspection was taking a long time and there could be a problem with one of the playoff cars. All Logano could do was wait and wonder if there truly was something amiss with Alex Bowman's car and if it was egregious enough to push Logano into the round of eight.
“NASCAR, man. Expect the unexpected,” Logano said Tuesday. “You just roll with the punches and go with the flow and just continue on. I feel like these days, more and more, there are just crazy things that can happen. I just go with it."
Sure enough, Bowman's car was found to be underweight and he was disqualified. The penalty dropped Bowman in the standings, and as soon as Hendrick Motorsports declined Monday night to appeal, Logano was back in title contention.
“I was honestly surprised. I had heard rumors there was a delay in tech, some of those things going on. But usually nothing happens,” Logano said. “Would be in? That's the first question you have to ask. And then you are still cautiously optimistic, so you just keep going on with your life and prepare for the next race.”
That next race is Sunday at Las Vegas Motor Speedway, where Logano is a three-time race winner and has started from the pole three different times.
Logano will race over the next three weeks Team Penske teammate and reigning Cup Series champion Ryan Blaney, the Hendrick Motorsports trio of William Byron, Chase Elliott and Kyle Larson, Joe Gibbs Racing drivers Christopher Bell and Denny Hamlin and Tyler Reddick of 23XI Racing for the four spots in the championship-deciding finale.
Should he emerge as the title winner at Phoenix Raceway in November, Logano will be the only active three-time Cup Series champion in NASCAR. Kyle Busch, who did not make the playoffs, is the only active driver alongside Logano with two titles.
Logano said his No. 22 Ford team will not make any changes to its approach as the team heads to Las Vegas, Homestead-Miami Speedway and Martinsville Speedway in Virginia vying for a spot in the finals.
“Same way if we made it any other way, you go out there and attack the positives,” Logano said. "I feel that we've been steadily getting better and improving throughout the season to where we are now. The speed we had at The Roval looked pretty solid to me, to where we are a championship-four caliber race team.
“The stats may not look like it. We may look like we're underdogs from the outside looking in, but internally we feel very confident in our race team that we can make a run at this thing and get us into the championship four," Logano continued. "And we've seen in the past where if you can get in there, anything can happen at Phoenix.”
It starts Sunday at Las Vegas, where Logano won the 2022 playoff race that pushed him to his second Cup title. Larson won last year's playoff race at Las Vegas, as well as the spring race there earlier this season.
But Logano likes his odds now that he's been given this second chance.
“We've done it before,” he said, “we can do it again.”
___
AP auto racing: https://apnews.com/hub/auto-racing
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/sports/logano-gets-back/XE2TSB5L6FGVFOBUN3F44MW5EU/ | 2024-10-15T17:57:35Z |
Savills United Arab Emirates Earns The Great Place to Work Certification 2024
Date
10/15/2024 9:48:10 AM
(MENAFN- Savills) Savills United Arab Emirates, a leading global real estate adviser, is proud to have earned the Great Place to Work Certification for 2024. This achievement underscores the company’s commitment to fostering an inclusive, collaborative, and empowering work environment across all its UAE offices. With a heritage spanning more than 160 years, Savills continues to prioritise employee well-being and professional growth as key pillars of its success.
Great Place to Work is the global authority on workplace culture, employee experience, and leadership behaviours proven to drive market-leading revenue, employee retention, and increased innovation. The certification is recognised worldwide as a mark of excellence for organisations that put people first.
The certification is based entirely on feedback from current employees regarding their experience at Savills UAE. In the survey, Savills employees reported feeling valued and supported from the moment they joined the company. Employees also highlighted a sense of pride in their work, as well as the friendly and welcoming environment that encourages authentic connections and mutual support among colleagues.
“At Savills, our people are at the heart of everything we do,” said Samar Mallah, HR Director at Savills Middle East. “Earning the Great Place to Work certification reflects our dedication to nurturing a thriving workplace culture and our commitment to evolving our employee proposition, which in turn enables us to continually grow and deliver exceptional service to our clients.”
The announcement comes on the heels of ambitions expansion plans announced by the company in early 2024, with a keen focus on the residential agency division. To meet the growing demand across the dynamic real estate market, especially the increasing activity in the UAE, Savills Residential Agency division will expand to over 100 property consultants by the end of 2024, led by the property agent Andrew Cummings, Head of Residential Agency, Middle East.
Savills has also strengthened its commercial agency offering by appointing a new head of Commercial Agency, Toby Hall, to respond to the large-scale leasing interest from corporate entities witnessed in UAE, and Dubai in particular.
These large-scale expansion efforts reinforce Savills commitment to delivering excellence to its clients.
MENAFN15102024007367015881ID1108780716
Legal Disclaimer:
MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780716/Savills-United-Arab-Emirates-Earns-The-Great-Place-to-Work-Certification-2024 | 2024-10-15T17:57:37Z |
ACMSD inhibition offers potential benefit across a broad range of liver and kidney diseases
MENLO PARK, Calif.--(BUSINESS WIRE)--#OrsoBio--OrsoBio, Inc. (“OrsoBio” or “the Company”), a clinical-stage biopharmaceutical company developing treatments for obesity and obesity-associated disorders, together with a team of academic researchers from Europe, Japan, and the United States, published promising preclinical data regarding the potential of ACMSD inhibition in animal and cellular models of metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH). In addition to enhancing synthesis of NAD+, a key co-factor in diverse bodily processes, the researchers discovered that ACMSD inhibition prevents DNA damage and cellular redox stress, leading to significantly reduced inflammation and fibrosis due to MASH.
“We see tremendous therapeutic potential in ACMSD inhibitors across a spectrum of metabolic and inflammatory hepatic and renal diseases,” said Mani Subramanian, MD, PhD, Chief Executive Officer of OrsoBio. “The mechanism of action of ACMSD inhibition is highly complementary to our broader portfolio, including mitochondrial protonophores and an ACC2 inhibitor, as they target causal drivers of inflammation and fibrosis. Their potential therapeutic impact extends well beyond the obesity-associated diseases that are the focus of the rest of our pipeline.”
The study, published in the Journal of Hepatology, investigates the mechanistic role and therapeutic implications of inhibiting a key enzyme involved in cellular energy metabolism for the potential treatment of MASLD/MASH. Researchers found that inhibition of ACMSD (aminocarboxymuconate semialdehyde decarboxylase), an enzyme restricted to liver and kidney, enhances de novo NAD+ synthesis and significantly reduces DNA damage responses in liver, thereby preventing MASLD/MASH progression.1 These findings were reproduced in mouse models and in a human liver organoid (HLO) model of steatohepatitis.
“Enhancing NAD+ levels in hepatocytes represents an attractive yet underexplored area for preventing redox stress. We observed that inhibiting ACMSD in human hepatocytes, both ex vivo and in vivo, increases NAD+ levels, enhances mitochondrial respiration, and helps maintain genomic stability,” said Takanori Takebe, MD, PhD, Associate Professor at Cincinnati Children’s Hospital Medical Center and a scientific advisor to OrsoBio. “Here, we have reproduced our earlier findings from a study published in Cell that demonstrated the benefits of alternative approaches to cellular NAD+/redox/mitochondrial modulation in a MASH organoid model from human induced pluripotent stem cells (iPSCs).2 Importantly, ACMSD inhibition alleviated phenotypes found in MASH organoids even from iPSCs of genetically at-risk individuals.”
“Prevention and delayed progression of organ injury in the setting of acute and chronic liver and kidney diseases is a major unmet medical need,” said Johan Auwerx, MD, PhD, Professor at the École Polytechnique Fédérale de Lausanne (EFPL), Switzerland, and a scientific advisor to OrsoBio. “This research suggests that pharmacologic ACMSD inhibition could have a role in advanced disease where there is both metabolic and mitochondrial dysfunction leading to cellular redox mediated exacerbation of the DNA damage response, which sustains progressive inflammation and fibrosis. We look forward to continued collaboration with the OrsoBio team to evaluate the benefits of ACMSD inhibition as monotherapy and in combination with other mechanisms to better understand its therapeutic potential.”
A range of proprietary compounds within OrsoBio’s ACMSD inhibitor portfolio are currently being evaluated for their potential to replenish NAD+ and improve mitochondrial function in metabolic and inflammatory liver and kidney disorders. The company plans to complete lead optimization and IND-enabling activities in 2025.
About ACMSD
ACMSD (aminocarboxymuconate semialdehyde decarboxylase) is a key enzyme involved in the de novo synthesis of NAD+ from tryptophan. Enhancing NAD+ synthesis by silencing or inhibiting ACMSD improves mitochondrial function, increases the lifespan of C. elegans, and protects against liver and kidney injury in mice. OrsoBio’s preclinical portfolio of ACMSD inhibitors is being advanced for the treatment of a range of metabolic and inflammatory liver and kidney disorders.
About OrsoBio, Inc.
OrsoBio, Inc. is a privately held, clinical-stage biopharmaceutical company dedicated to developing therapies to treat obesity and obesity-associated disorders, including type 2 diabetes, MASH, and severe dyslipidemias. OrsoBio currently has four programs in clinical and preclinical development with first-in-class compounds that address central pathways in energy metabolism. For more information, please visit www.orsobio.com.
1 Liu YJ, et al. J Hepatol 2024 Aug 22:S0168-8278(24)02484-X. doi: 10.1016/j.jhep.2024.08.009. Available: https://www.journal-of-hepatology.eu/article/S0168-8278(24)02484-X/fulltext.
2 Kimura M, et al. Cell 2022;185(22):4216-4232.e16. doi: 10.1016/j.cell.2022.09.031. Available: https://www.cell.com/cell/fulltext/S0092-8674(22)01250-8.
Contacts
Media Contact
Gwen Gordon
Gwen@gwengordonpr.com | https://www.biospace.com/news/orsobio-announces-publication-of-preclinical-data-on-novel-approach-for-regulating-metabolic-dysfunction-and-reducing-inflammation-and-fibrosis | 2024-10-15T17:57:37Z |
The DP World Tour is at Sotogrande, Spain for the penultimate event, the ‘Back 9’, before next week’s Genesis Championship in Korea
UAE resident Garrick Porteous (Eng) competing this week on the Challenge Tour in China - a big week for all. - Supplied photo
Our focus this week is on the Challenge Tour – and the $500,000 Hangzou Open in China – the penultimate event of the season, before the season ending Rolex Challenge Tour Grand Final supported by The R&A in Mallorca at the end of the month.
Dubai residents, Garrick Porteous (Eng) and Joshua Grenville-Wood (UAE) are in 52nd and 64th respectively in the Road to Mallorca Rankings and both need good weeks – if not exceptional weeks to get in the top 45 to play in Spain.
Porteous, 34 years-old is a winner this year – taking top prize and €45,148.70 as well as 320 Ranking points in the Abu Dhabi Challenge at Al Ain Equestrian, Shooting and Golf Club back in April.
The top 20 players in the CT Rankings after Spain will earn their 2025 DP World Tour Cards – all part of the pyramid eco-system of professional golf around the world.
The DP World Tour is at Sotogrande. Defending champion and Dubai resident Adrian Meronk (Pol) is not in the field but is committed to play in the DP World Tour Play-offs at both the Abu Dhabi HSBC Championship at Yas Links and DP World Tour Championship at Jumeirah Golf Estates on the Earth course next month.
The field in Spain includes: Jon Rahm (Spain), the Hojgaard twins (Den), Victor Perez (Fr), David Puig (Spain) and Eugenio Chacarra (Spain) as well as last week’s FedEx Open de France champion, Dan Bradbury (Eng) and a host of DP World Tour stars.
The importance of the Rolex Series events on the DP World Tour’s Race to Dubai is well illustrated by the fact that Meronk last played in a DP World Tour event at the HERO Dubai Desert Classic and is still 34th in the Rankings – without significantly performing that well in all four Majors. These big events attract the best players and are really Ranking movers, as well as Official World Golf Ranking (OWGR) movers - anchoring the DP World Tour Rankings.
This week’s event in Spain is the penultimate event on DP World Tour’s ‘Back 9’ before next week’s Genesis Championship in Korea and then to the DP World Tour Play-Offs.
An exciting climax to the season is ahead of us – with it happening here in the UAE.
Schedule
PGA Tour
Thursday 17th October – 20th October, 2024
Shriners Children’s Open
Venue: TPC Summerlin, Las Vegas, Nevada, US
Purse: $7 million
DP World Tour
Thursday 17th October – 20th October, 2024
Estrella Damm N.A. Andalucia Masters
Venue: Real Club de Golf Sotogrande, San Roque, Andalucia, Spain
Purse: $3.25 million
Challenge Tour
Thursday 17th October – 20th October, 2024
Hangzou Open
Venue: Hangzou West Lake Golf Club, Hangzou, China
Purse: $500,000
LPGA
Thursday 17th October – 20th October, 2024
BMW Ladies Championship
Venue: Seawon-gil, Republic of Korea
Purse: $2.2 million | https://www.khaleejtimes.com/sports/this-week-in-golf-dubai-residents-porteous-and-grenville-wood-looking-for-strong-finishes-on-the-ch | 2024-10-15T17:57:38Z |
If you were a fan of the 2024 quarterback class, Week 6 was something special, as a whopping four rookie quarterbacks scored 20 or more fantasy points. Caleb Williams was the star of the show, of course, leading all QBs with 29.64 fantasy points, including four touchdowns through the air and 56 rushing yards to the joy of fantasy managers.
Unfortunately, most folks have already caught onto his fantasy relevance, so he's not accessible on most waiver wires. You might just find some surprise value, however, in New England in No. 3 pick Drake Maye or Broncos QB Bo Nix, both currently unrostered in more than half of Yahoo leagues.
Maye was the fourth rookie quarterback to make his NFL debut this past week, having an up-and-down outing where he posted 243 passing yards, 3 TDs and 2 INTs but saved his fantasy day with another 38 yards on the ground. Maye led the team in rushing, showcasing some of his athleticism which is a huge plus for fantasy managers. This week, the Patriots will travel overseas to London to face the Jacksonville Jaguars who just allowed a monster breakout game to Williams.
Nix is interesting, too, heading into Week 7 having scored 19+ fantasy points in three of the last four weeks, including 21+ fantasy points in each of the last two. Nix has been showcasing his mobility as well, with 47 or more rushing yards or a rushing touchdown in three of the last four games.
Find out where rookie Drake Maye, Nix and the rest of the quarterbacks slated to start fall in our team's Week 7 quarterback rankings:
Are you trusting any of these rookies in your Week 7 lineups? | https://www.actionnewsjax.com/news/national/fantasy-football/J5SSVSQP26NVDF4EEF5N7D5AJE/ | 2024-10-15T17:57:38Z |
Eaton introduces Bridge Energy Control, featuring energy monitoring and load control via dynamic tariffs, as a step towards better home energy management
Date
10/15/2024 9:48:27 AM
(MENAFN- teamlewis) Dubai, UAE – Eaton, a global expert in intelligent power management, today announced Bridge Energy Control for its xComfort ecosystem. The update will give homeowners more control over their energy bills by providing them with visibility of the energy usage of its connected devices, as well as the rest of the home when it is paired with the new energy meter that is also now available.
This new development in smart home technology combines device-level energy monitoring with load control based on dynamic tariffs. It is ideal for installers and homeowners seeking energy efficiency alongside home automation. When installed with Eaton's new energy meter, xComfort Bridge can also extend energy monitoring to the entire home.
Users operate Bridge Energy Control via an app that visualises its tariff-based load control and energy monitoring features. The load control feature tracks local energy tariffs to provide averages and uses this information to forecast energy expenditure. It supports several types of tariffs, including fixed, day-night, and dynamic.
The tariff modes in the device are categorised as cheap, normal, or expensive based on the average tariff rates of the location. The overall energy cost can be decreased by automatically switching to cheaper options for controllable electrical loads – an example of this might be reducing electrical floor heating to lower temperature setpoints during periods when tariffs are expensive. While this ensures an overall balance between comfort and energy costs, users can over-ride modes as required.
When coupled with Eaton's new energy meter, Bridge Energy Control enables users to monitor the total energy consumption of their home. The app offers 'Current View' and 'Historical View' to monitor energy consumption of all devices connected to the xComfort ecosystem. The Current View shows the energy consumption within a 48-hour timeframe. The Historical View shows energy consumption over time and allows users to select a week, or month, or year of stored data. In both views, users can filter by load type, room or device, or a selected combination of devices connected to xComfort.
Eaton now offers two energy control bundles for xComfort to customers: one with the energy meter and one without, each bundle containing actuators for controlling electrical floor heating, electrical loads like water heaters, and a Room Controller Touch for regulating room temperature. These bundles provide an all-in-one solution for customers.
MENAFN15102024007657016522ID1108780719
Legal Disclaimer:
MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. | https://menafn.com/1108780719/Eaton-introduces-Bridge-Energy-Control-featuring-energy-monitoring-and-load-control-via-dynamic-tariffs-as-a-step-towards-better-home-energy-management | 2024-10-15T17:57:38Z |
Out-of-form Yusuf Maart about to lose Kaizer Chiefs captaincy? - The former Orlando Pirates midfielder is not 'the best leader' for Amakhosi
The 2014/15 PSL title-winning defender believes the current Amakhosi leader has not met all the requirements that are vital for a leader.
Article continues below
Article continues below
Article continues below
- Maart was confirmed Chiefs captain this season
- He succeeded Khune
- What former Amakhosi defender thinks | https://www.goal.com/en-za/lists/out-of-form-yusuf-maart-about-to-lose-kaizer-chiefs-captaincy-the-former-orlando-pirates-midfielder-is-not-the-best-leader-for-amakhosi/blta8b8ec963c94f8c5 | 2024-10-15T17:57:41Z |
PHILADELPHIA — (AP) — The Philadelphia Phillies signed manager Rob Thomson to a one-year contract extension through the 2026 season after he led the team to three straight trips to the playoffs.
The 61-year-old Thomson guided the Phillies to the 2022 World Series and the 2023 National League Championship Series and led them this season to their first NL East title since 2011. The Phillies were eliminated in four games by the New York Mets in the National League Division Series.
Thomson's .575 winning percentage is the best for any manager in franchise history. His contract was set to expire after the 2025 season.
“Year by year is good with me,” Thomson said Tuesday of the extension. “I've mentioned many times this is the only place I want to be. This will be my last stop.”
Phillies president of baseball operations Dave Dombrowski said the entire coaching staff — which includes polarizing hitting coach Kevin Long — will return next season, as well.
“Many managers will say it, but I truly believe we have the best coaching staff in baseball,” Thomson said.
Coming off a 95-67 season, Dombrowski made clear he was happy with the direction of the team under the manager affectionately known by his players as Topper.
“I think we have a good coaching staff, primarily,” Dombrowski said during Tuesday's announcement. “They do a very efficient job. They did lead us to 95 wins.”
Thomson has a 280-155 record since the veteran bench coach replaced Joe Girardi as Phillies manager on June 3, 2022.
Dombrowski said it was important for the team not to enter the 2026 season with a lame-duck manager.
“He's done a good job for us, been a very successful manager,” Dombrowski said. “There's been very few clubs in baseball that have made the postseason three years in a row. He has done that. We've been a very good club under his guidance. It's also one where I think stability in the manager's spot, I don't think going into the manager's last year is ever good situation to be in, if you can prevent that from happening. He deserves the extension in that regard.”
Thomson has been with the club since the 2018 season when he was first hired as bench coach under former manager Gabe Kapler.
He spent 28 years as a member of the New York Yankees organization (1990-2017), including 10 seasons on the major league coaching staff as bench coach (2008, 2015-17) and third base coach (2009-14).
___
AP MLB: https://apnews.com/MLB
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/sports/phillies-sign/D3WMXLEORFDEPKNTYGMTJUBYSQ/ | 2024-10-15T17:57:42Z |
Residents and visitors will be able to enjoy an entirely new way of experiencing events, concerts, and shows
UAE's capital city is set to be the next location to get the landmark Las Vegas Sphere, Abu Dhabi's Department of Culture and Tourism (DCT) announced on Tuesday, October 15.
Residents and visitors will be able to enjoy an entirely new way of experiencing events, concerts, and shows. The medium of entertainment is expected to match the scale of the Las Vegas Sphere with a capacity 20,000. It is also expected to draw visitors all year round.
The authority did not specify exactly where the sphere will be located, however, it did mention that the Sphere will be at a prime spot in the emirate.
Stay up to date with the latest news. Follow KT on WhatsApp Channels.
James L Dolan, executive chairman and chief executive officer, Sphere Entertainment, said, “Sphere is redefining live entertainment and extending the reach of its transformative impact."
Mohamed Khalifa Al Mubarak, chairman of DCT Abu Dhabi, said: “We are excited to bring Sphere to Abu Dhabi in partnership with Sphere Entertainment, providing our residents and visitors with an extraordinary new form of entertainment. Sphere Abu Dhabi will seamlessly integrate advanced technology with captivating storytelling, creating unforgettable memories for everyone who visits."
Under the terms of the partnership, which are yet to be finalised, DCT Abu Dhabi will pay Sphere Entertainment a franchise initiation fee for the right to build the venue, utilising it’s proprietary designs, technology, and intellectual property.
Construction will be funded by DCT Abu Dhabi, with Sphere Entertainment’s team of experts providing services related to development, construction, and pre-opening of the venue.
ALSO READ: | https://www.khaleejtimes.com/uae/abu-dhabi-announced-as-next-location-for-viral-las-vegas-sphere | 2024-10-15T17:57:44Z |
Congratulations, fantasy football managers! Fantasy's top-scoring defense is back in the mix this week as the Minnesota Vikings return from a bye, currently ranked top-three in sacks (20) while leading the NFL with 11 interceptions despite playing just five games. The bad news? They're set to face the Detroit Lions, who are allowing the fourth-fewest fantasy points per game to opposing defenses.
Elsewhere, the Chargers will take on the Las Vegas Raiders who are without recently-traded WR Davante Adams and could be missing a number of other top receiving options with Jakobi Meyers banged up with an ankle injury and Michael Mayer out due to personal reasons. The Raiders have allowed 11 or more fantasy points in four of six games this season, including each of the last three.
Find out where the Chargers D/ST landed in our team's Week 7 defense rankings:
Who will you start at D/ST in Week 7? | https://www.actionnewsjax.com/news/national/fantasy-football/OC4X5UYJCIMCHS4HBEYLHAPK5I/ | 2024-10-15T17:57:44Z |
Novel engineered Fc-fused pan-IgG protease demonstrates deep, rapid and sustained reduction of IgG levels and ability to address multiple pathogenic mechanisms as a single drug molecule
Preclinical data supports potential for S-1117’s multi-mechanistic action to address unmet need in myasthenia gravis
Company expects to initiate first-in-human Phase 1 clinical trial of S-1117 in 1H 2025
WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the presentation of new preclinical data for its pan‑immunoglobulin G (IgG) sculpting enzyme candidate, S-1117, at the Myasthenia Gravis Foundation of America (MGFA) Scientific Session at the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) 2024 annual meeting in Savannah, Georgia.
S-1117 is a novel engineered Fc-fused pan-IgG protease targeting IgG autoantibodies that play a key role in the pathogenesis of a range of chronic and acute autoantibody mediated diseases, including myasthenia gravis (MG), a chronic neuromuscular autoimmune disorder. Seismic plans to initiate a Phase 1 clinical trial of S-1117 in healthy volunteers in the first half of 2025.
“S-1117 has shown the unique ability to target multiple orthogonal pathogenic mechanisms within a single molecule, and we believe this multi-mechanistic approach has the potential to drive deeper responses and offer improved clinical outcomes for MG patients, as well as for patients with other autoantibody-mediated diseases,” said John Sundy, MD, PhD, Chief Medical Officer and Head of R&D at Seismic Therapeutic. “Despite recent treatment advancements, there remains a significant opportunity to address the large proportion of MG patients who do not achieve remission or low disease activity with currently approved therapies. We believe S‑1117 can offer advantages over existing treatment options and look forward to advancing S‑1117 into first-in-human Phase 1 clinical studies in the first half of next year.”
The S-1117 preclinical data presented at AANEM showed deep, rapid and sustained reduction of all IgG subclasses. S-1117 also demonstrated the ability to directly cleave circulating and immune complexed IgG, as well as the IgG B cell receptor expressed on memory B cells. Moreover, current S-1117 PK/PD modeling indicates the potential for a convenient small volume, subcutaneous, self-administered treatment regimen administered every 4-6 weeks.
Highlights of the Presentation
In vitro, S-1117 was shown to cleave soluble forms of IgG from healthy volunteers and MG patients. The results support additional key attributes of S-1117:
- Cleaves all IgG subclasses, including IgG3, in plasma of healthy individuals and MG patients;
- Achieves a magnitude of soluble IgG cleavage in vitro from MG patients similar to healthy volunteers; and
- Cleaves preformed immune complexes, which drive injury to tissues, as well as the B cell receptor.
In vivo studies performed with S-1117 in rabbit and mouse models showed rapid, deep and sustained IgG reduction and demonstrated cleavage of the B cell receptor within hours after both intravenous and subcutaneous administration.
Projections of human PK and PD through quantitative systems pharmacology (QSP) modeling for S-1117 indicate that infrequent chronic low doses can achieve titratable IgG reductions of 90% or greater. PK/PD modeling further supports the potential for a subcutaneous, self-administered treatment regimen to achieve therapeutic levels of IgG reduction at doses as low as <1mg/kg of drug administered monthly. In addition, given the rapid onset of action, S-1117 is predicted to be applied to acute conditions, such as MG crisis.
The poster for the data presented at AANEM is available here on Seismic’s website.
About Seismic Therapeutic
Seismic Therapeutic™ is a biotechnology company making a major shift in how immunology therapies are discovered and developed, enabled by machine learning. The company has a growing preclinical stage best-in-class and first-in-class biologics pipeline, derived from its integrated IMPACT platform, to control dysregulated adaptive immunity and address multiple autoimmune diseases. The company is backed by a strong syndicate of life sciences investors and is located in the Boston biotechnology hub. For more information, please visit www.seismictx.com and follow us on LinkedIn and on X @Seismic_Tx.
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emiley.demick@precisionaq.com | https://www.biospace.com/news/seismic-therapeutic-presents-new-preclinical-data-on-s-1117-in-autoantibody-mediated-diseases-including-myasthenia-gravis-at-mgfa-scientific-session-at-aanem-annual-meeting | 2024-10-15T17:57:47Z |
GettyMitchell FrettonPremier League postpone meeting with clubs over Man City legal hearings as APT saga rages onPremier LeagueManchester CityThe Premier League have pushed back a meeting with clubs other than Manchester City to discuss their recent legal battle.Article continues belowArticle continues belowArticle continues belowMan City in huge legal battle with Premier LeagueChampions won case regarding commercial deals Premier League due to update other clubs on outcome Follow GOAL on WhatsApp! 🟢📱Article continues below | https://www.goal.com/en-za/lists/premier-league-postpone-meeting-clubs-over-man-city-legal-hearings-apt-saga-rages-on/bltfad9e3d42b188355 | 2024-10-15T17:57:48Z |
BCCD panel spotlight business benefits of RAK’s sustainability agenda
Date
10/15/2024 9:48:34 AM
(MENAFN- The Loop)
Representatives from the government and private sectors in Ras Al Khaimah (RAK) have revealed the pioneering measures being implemented to promote greener business practices in the Nature Emirate. In a panel discussion convened by the British Chamber of Commerce Dubai (BCCD), business founders highlighted the benefits of setting up in RAK, while representatives of the municipality and local agencies explained the cost savings and incentives for organisations committing to sustainable operations.
Commercial Director of Marjan, Khaled Assaf, opened the discussion with an overview of the masterplan for the RAK Central project, a progressive development of residential, office and lifestyle facilities, underpinned by sustainability principles. The development is being constructed within the LEED green building framework and is designed as a walkable community to promote sustainable mobility.
Joining the panel discussion were Ramy Jallad, Group CEO of Ras Al Khaimah Economic Zone (RAKEZ); Rukhsana Kausar, Founder of Liquid of Life; Alka Winter, Vice President of Destination & Marketing Communications at RAK Tourism and Development Authority; Nick Glover, Middle East Social Impact Director at Waste to Wonder; and Dr Pablo Izquierdo, Energy Services Manager, Energy Efficiency and Renewables Office (Reem) at RAK Municipality.
Opening the discussion, Jallad explained how the Emirate is attracting new businesses with its sustainability agenda. He said, “RAKEZ’s strategy is to establish a thriving ecosystem centred on ESG principles, where sustainability is not just a responsibility but a catalyst for business growth. We offer incentives to developers committed to green building and energy efficiency; while ensuring they have access to essential business services and infrastructure locally. With the Emirate’s Energy Efficiency and Renewables Strategy 2040 driving tangible results, we are encouraging energy-efficient practices across industries. Our commitment to energy conservation, aligned with the UAE’s Net Zero by 2050 framework, is already making a measurable impact through initiatives like energy audits, innovative recycling, and green energy solutions. Partnering with government authorities, industry leaders, and communities, we are shaping a future for Ras Al Khaimah where economic progress and environmental stewardship go hand in hand.”
Discussing the approach of RAK Municipality, Dr Izquierdo revealed how sustainability has become embedded in the government culture. He said, “The Ras Al Khaimah government was the first in the world to achieve ISO 50001 energy management certification across all of its entities. As well as a change in mindset, we have achieved 25% cost savings across the municipality.”
As founder of a business with sustainability at its core, Kausar explained why she chose to set up the manufacturing of her filtered drinking water solution to Ras Al Khaimah. She said, “When we explored the business opportunities in RAK we found that RAKEZ offered an environment for us to grow in the right way and the Emirate also provides a different lifestyle, with its natural beauty and tranquillity. We want to create a community-based approach to sustainability and there are more opportunities being created in Ras Al Khaimah to adopt practices that have an impact.”
Exemplifying the community approach, Glover shared how Waste to Wonder is working in partnership across RAK to promote sustainability and improve lives. He said, “As an ethical clearance service we take redundant items to be repurposed, so they can be reused for the benefit of people less privileged. We’ve worked with a group of schools to clear unused furniture and benefited thousands of children who don’t have the same opportunities in life. The aim is to create partnerships that deliver social impact and elevate the Emirate.”
Representing the RAK Tourism and Development Authority, Winter went on to explain the actions the organisation is implementing to become a regional champion in sustainable tourism. She said, “We’ve worked with EarthCheck to assess our performance against 10 sustainability metrics and introduced Responsible RAK, our own assessment program for tourism businesses. This enables us to identify those organisations that need support and we have seen some positive results, with better waste management and water saving across the industry.”
Moderated by BCCD CEO, Katy Holmes, the panel discussion followed the recent launch of the Chamber’s Green agenda and the signing of an MoU between RAKEZ and BCCD earlier this year. Commenting on the event, Holmes said, “Increasingly, ESG has become the key lens through which we take our business decisions. Events like this BCCD business briefing create opportunities for open and constructive dialogue to inspire and accelerate impactful change both in the public and private sectors.”
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PITTSBURGH — (AP) — Russell Wilson's time may be fast approaching in Pittsburgh.
Coach Mike Tomlin said Tuesday that Wilson is "in consideration" to be the starting quarterback when the Steelers (4-2) host the New York Jets (2-4) on Sunday night. The 35-year-old nine-time Pro Bowler has spent the past six weeks recovering from a calf injury he aggravated a couple of days before the season opener.
While Tomlin stressed that Justin Fields "has been really good" while filling in for Wilson and the team has "been really good at times," the NFL's longest-tenured coach added that good was "not to be confused with great."
Enter Wilson, who won the starting job at the end of training camp before tweaking the calf less than 72 hours before a Week 1 visit to Atlanta. Tomlin saw enough of Wilson in practice last week to have him serve as the backup behind Fields during a 32-13 win in Las Vegas, and there's a very real chance they could swap roles against the Jets.
“This is a competitive league, man,” Tomlin said. “We’re trying to position ourselves to be that team. And we got a player with talent who hadn’t had an opportunity to play. So we’re going to potentially explore those things.”
Fields has been efficient and occasionally spectacular during his six-week audition. He's also largely avoided the kinds of mistakes that were a common thread during his three years in Chicago, throwing just one interception in 160 attempts. His accuracy, however, had dipped of late. Fields has completed just 57% (29 of 51) of his passes over his past eight quarters, down from 69% (77 of 111) across the opening month of the season.
The Steelers are also 28th in passing and 20th in scoring, riding a soft(ish) early season schedule and a disruptive defense led by All-Pro linebacker T.J. Watt to a tie atop the AFC North with rival Baltimore. After a pair of home primetime games against the New York City area teams — the Jets on Sunday, the Giants on Oct. 28 — the sledding figures to get far heavier once the calendar flips to November and Wilson's resume may be too tantalizing for Tomlin to pass up.
Tomlin cautioned that the decision to give Wilson reps with the first team in practice this week has more to do with Wilson's experience and his resume than Fields' performance.
“Justin has been an asset to us," Tomlin said.
Just not enough of one for Tomlin to definitively hand the starting job to Fields outright. Tomlin declined to get into specifics on how he will divide the practice snaps with the first team and doesn't expect to make a decision on who will start against the Jets until later in the week.
"We’re just going to roll the ball out, let both guys work and make decisions from there," Tomlin said.
Fields' play has allowed the Steelers to bring Wilson — who turns 36 next month — along slowly. Wilson initially injured the calf when the team reported to training camp in July and there was a concern when he aggravated it that it could lead to something more serious.
Wilson has steadily improved and showed Tomlin last week that he could protect himself in practice. The next step will be knocking off whatever rust might remain from a month-plus of relative inactivity, though Tomlin doesn't sound overly concerned.
Whoever the quarterback is will likely be playing behind a seventh different offensive line combination in as many weeks with rookie center Zach Frazier out with an ankle injury sustained against the Raiders. Fields' mobility — he's already run for five touchdowns — has helped offset the constant churn in front of him. That's not a tool that Wilson has had since the height of his “Let Russ Cook” days with Seattle several years ago.
Asked how the offense might change with Wilson behind center, Tomlin smiled and said “it remains to be seen. And I think that’s one of the cute things about this discussion.”
NOTES: LB Nick Herbig (hamstring) will miss his second straight game. ... There's a chance OLB Alex Highsmith (groin), out since a win over the Los Angeles Chargers on Sept. 22, could return. ... RB Cordarrelle Patterson (ankle) may also be available after missing two games.
___
AP NFL: https://apnews.com/hub/nfl
Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission. | https://www.wftv.com/sports/steelers-qb-russell/UDOOWOLXYBFXXGPG2GUDXBV42I/ | 2024-10-15T17:57:49Z |
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