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NEW YORK, June 8, 2022 /PRNewswire/ -- The Industrial Fasteners market will register an incremental spend of about USD 21.3 Billion, growing at a CAGR of 4.50% during the five-year forecast period. A targeted strategic approach to Industrial Fasteners sourcing can unlock several opportunities for buyers. This report also offers market impact and new opportunities created due to the COVID-19 pandemic. Key Highlights Offered in the Report: - Information on how to identify strategic and tactical negotiation levels that will help achieve the best prices. - Gain information on relevant pricing levels, detailed explanation on pros and cons of prevalent pricing models. - Methods to help engage with the right suppliers and discover KPI's to evaluate incumbent suppliers. Get a free sample report for more information Insights into buyer strategies and tactical negotiation levers: Several strategic and tactical negotiation levers are explained in the report to help buyers achieve the best prices for the Industrial Fasteners market. The report also aids buyers with relevant Industrial Fasteners pricing levels, pros, and cons of prevalent pricing models such as volume-based pricing, spot pricing, and cost-plus pricing and category management strategies and best practices to fulfil their category objectives. For more insights on buyer strategies and tactical negotiation levers, www.spendedge.com/report/industrial-fasteners-market-procurement-research-report Key Drivers and Trends Fueling Market Growth: The pressure from substitutes and a moderate level of threat from new entrants has resulted in the low bargaining power of suppliers. Price forecasts are beneficial in purchase planning, especially when supplemented by the constant monitoring of price influencing factors. During the forecast period, the market expects a change of 3%-5%. - Identify favorable opportunities in Industrial Fasteners TCO (total cost of ownership). - Expected changes in price forecast and factors driving the current and future price changes. - Identify pricing models that offer the most rewarding opportunities. SpendEdge presents a detailed picture of this procurement market by the way of study, synthesis, and summation of data from multiple sources. Our Industrial Fasteners market procurement report covers the following areas: - Industrial Fasteners Supplier Selection Criteria, Supplier Evaluation Metrics, and SLA that Buyers Should Consider - Industrial Fasteners Market's Most Adopted Procurement Strategies by Buyers Across Industries - Industrial Fasteners Market's Major Pricing Models Adopted by Buyers in Industrial Fasteners Market Some of the top Industrial Fasteners suppliers listed in this report: This Industrial Fasteners procurement intelligence report has enlisted the top suppliers and their cost structures, SLA terms, best selection criteria, and negotiation strategies. - Alcoa Corp. - LISI SA - Nifco Inc. To get instant access to over 1000 market-ready procurement intelligence reports without any additional costs or commitment. Table of Content - Executive Summary - Market Insights - Category Pricing Insights - Cost-saving Opportunities - Best Practices - Category Ecosystem - Category Management Strategy - Category Management Enablers - Suppliers Selection - Suppliers under Coverage - US Market Insights - Category scope - Appendix About SpendEdge: SpendEdge shares your passion for driving sourcing and procurement excellence. We are the preferred procurement market intelligence partner for 120+ Fortune 500 firms and other leading companies across numerous industries. Our strength lies in delivering robust, real-time procurement market intelligence reports and solutions. Contacts SpendEdge Anirban Choudhury Marketing Manager Ph No: +1 (872) 206-9340 https://www.spendedge.com/contact-us SOURCE SpendEdge	https://www.prnewswire.com/news-releases/global-industrial-fasteners-market-sourcing-and-procurement-intelligence-report-top-spending-regions-and-market-price-trends-spendedge-301562779.html	2022-06-08T12:03:21	en	0.877922
NEW YORK, June 8, 2022 /PRNewswire/ -- The hair color market size is set to grow by USD 18.09 billion from 2021 to 2026, progressing at a CAGR of 8.21% according to the latest market report by Technavio. 30% of the market's growth will originate from Europe during the forecast period. The UK is the key market for hair color in Europe. Market growth in this region will be slower than the growth of the market in other regions. The intense competition among vendors, leading to the expansion of distribution networks and the adoption of multichannel marketing strategies, especially in Western European countries will facilitate the hair color market growth in Europe over the forecast period. For more insights on the contribution of each region - Download a sample now! Hair Color Market 2022-2026: Scope . Our hair color market report covers the following areas: Hair Color Market 2022-2026: Vendor Analysis The hair color market is fragmented and the vendors are deploying growth strategies such as focusing on product innovations by bringing about the concept of product differentiation and new product developments to compete in the market. Amway Corp., Avon, Cadiveu Professional, Chatters Ltd. Partnership, Coty Inc., The Estee Lauder Co. Inc., Godrej and Boyce Manufacturing Co. Ltd., Henkel AG and Co. KGaA, Hoyu Co. Ltd., John Paul Mitchell Systems, Kao Corp., LOreal SA, Madison Reed Inc., Moroccanoil Inc., NATULIQUE Ltd., NATURIGIN, Revlon Inc., Shiseido Co.Ltd., Surya Brasil, Tints of Nature, Tish and Snookys NYC Inc., and Unilever PLC are some of the major market participants. - Amway Corp. - The company offers color CREATION permanent hair color which has been formulated with natural extracts and conditioners to create a unique blend of ingredients for protecting the scalp and hair. - To know about all major vendor offerings - Download a sample now! Hair Color Market 2022-2026: Drivers & Challenges The innovation in product formulation and formats, growth in novelty color segment as a premium product & influence through social media and blogging will offer immense growth opportunities. However, the limited consumer pool for novelty and premium hair colors in developing countries will challenge the growth of the market participants. Hair Color Market 2022-2026: Segmentation Analysis - Product - Permanent - Semi-permanent - Temporary - Highlights And Bleach - End-user - Women - Men - Unisex - Geography - Europe - North America - APAC - South America - Middle East And Africa To know the market contribution of each segment - Download a sample now! The competitive scenario provided in the Hair Color Market report analyzes, evaluates, and positions companies based on various performance indicators. Some of the factors considered for this analysis include the financial performance of companies over the past few years, growth strategies, product innovations, new product launches, investments, growth in market share, etc. Don't wait, Make a strategic approach & boost your business goals with our Hair Color Market Forecast Report - Buy Now! Hair Color Market 2022-2026: Key Highlights - CAGR of the market during the forecast period 2022-2026 - Detailed information on factors that will assist hair color market growth during the next five years - Estimation of the hair color market size and its contribution to the parent market - Predictions on upcoming trends and changes in consumer behavior - The growth of the hair color market - Analysis of the market's competitive landscape and detailed information on vendors - Comprehensive details of factors that will challenge the growth of hair color market vendors Related Reports: - The hair color spray market share is expected to increase to USD 340.97 million by 2026, and the market's growth momentum will accelerate at a CAGR of 4.54%. Download a sample now! - The hair wigs and extension market share is expected to increase by USD 5.26 billion from 2021 to 2026, and the market's growth momentum will accelerate at a CAGR of 9.82%. Download a sample now! Table Of Contents : 1 Executive Summary - 1.1 Market overview - Exhibit 01: Executive Summary – Chart on Market Overview - Exhibit 02: Executive Summary – Data Table on Market Overview - Exhibit 03: Executive Summary – Chart on Global Market Characteristics - Exhibit 04: Executive Summary – Chart on Market by Geography - Exhibit 05: Executive Summary – Chart on Market Segmentation by Product - Exhibit 06: Executive Summary – Chart on Market Segmentation by End-user - Exhibit 07: Executive Summary – Chart on Incremental Growth - Exhibit 08: Executive Summary – Data Table on Incremental Growth - Exhibit 09: Executive Summary – Chart on Vendor Market Positioning 2 Market Landscape - 2.1 Market ecosystem - Exhibit 10: Parent market - Exhibit 11: Market Characteristics 3 Market Sizing - 3.1 Market definition - Exhibit 12: Offerings of vendors included in the market definition - 3.2 Market segment analysis - Exhibit 13: Market segments - 3.3 Market size 2021 - 3.4 Market outlook: Forecast for 2021-2026 - Exhibit 14: Chart on Global - Market size and forecast 2021-2026 ($ million) - Exhibit 15: Data Table on Global - Market size and forecast 2021-2026 ($ million) - Exhibit 16: Chart on Global Market: Year-over-year growth 2021-2026 (%) - Exhibit 17: Data Table on Global Market: Year-over-year growth 2021-2026 (%) 4 Five Forces Analysis - 4.1 Five forces summary - Exhibit 18: Five forces analysis - Comparison between 2021 and 2026 - 4.2 Bargaining power of buyers - Exhibit 19: Chart on Bargaining power of buyers – Impact of key factors 2021 and 2026 - 4.3 Bargaining power of suppliers - Exhibit 20: Bargaining power of suppliers – Impact of key factors in 2021 and 2026 - 4.4 Threat of new entrants - Exhibit 21: Threat of new entrants – Impact of key factors in 2021 and 2026 - 4.5 Threat of substitutes - Exhibit 22: Threat of substitutes – Impact of key factors in 2021 and 2026 - 4.6 Threat of rivalry - Exhibit 23: Threat of rivalry – Impact of key factors in 2021 and 2026 - 4.7 Market condition - Exhibit 24: Chart on Market condition - Five forces 2021 and 2026 5 Market Segmentation by Product - 5.1 Market segments - Exhibit 25: Chart on Product - Market share 2021-2026 (%) - Exhibit 26: Data Table on Product - Market share 2021-2026 (%) - 5.2 Comparison by Product - Exhibit 27: Chart on Comparison by Product - Exhibit 28: Data Table on Comparison by Product - 5.3 Permanent - Market size and forecast 2021-2026 - Exhibit 29: Chart on Permanent - Market size and forecast 2021-2026 ($ million) - Exhibit 30: Data Table on Permanent - Market size and forecast 2021-2026 ($ million) - Exhibit 31: Chart on Permanent - Year-over-year growth 2021-2026 (%) - Exhibit 32: Data Table on Permanent - Year-over-year growth 2021-2026 (%) - 5.4 Semi-permanent - Market size and forecast 2021-2026 - Exhibit 33: Chart on Semi-permanent - Market size and forecast 2021-2026 ($ million) - Exhibit 34: Data Table on Semi-permanent - Market size and forecast 2021-2026 ($ million) - Exhibit 35: Chart on Semi-permanent - Year-over-year growth 2021-2026 (%) - Exhibit 36: Data Table on Semi-permanent - Year-over-year growth 2021-2026 (%) - 5.5 Temporary - Market size and forecast 2021-2026 - Exhibit 37: Chart on Temporary - Market size and forecast 2021-2026 ($ million) - Exhibit 38: Data Table on Temporary - Market size and forecast 2021-2026 ($ million) - Exhibit 39: Chart on Temporary - Year-over-year growth 2021-2026 (%) - Exhibit 40: Data Table on Temporary - Year-over-year growth 2021-2026 (%) - 5.6 Highlights and bleach - Market size and forecast 2021-2026 - Exhibit 41: Chart on Highlights and bleach - Market size and forecast 2021-2026 ($ million) - Exhibit 42: Data Table on Highlights and bleach - Market size and forecast 2021-2026 ($ million) - Exhibit 43: Chart on Highlights and bleach - Year-over-year growth 2021-2026 (%) - Exhibit 44: Data Table on Highlights and bleach - Year-over-year growth 2021-2026 (%) - 5.7 Market opportunity by Product - Exhibit 45: Market opportunity by Product ($ million) 6 Market Segmentation by End-user - 6.1 Market segments - Exhibit 46: Chart on End-user - Market share 2021-2026 (%) - Exhibit 47: Data Table on End-user - Market share 2021-2026 (%) - 6.2 Comparison by End-user - Exhibit 48: Chart on Comparison by End-user - Exhibit 49: Data Table on Comparison by End-user - 6.3 Women - Market size and forecast 2021-2026 - Exhibit 50: Chart on Women - Market size and forecast 2021-2026 ($ million) - Exhibit 51: Data Table on Women - Market size and forecast 2021-2026 ($ million) - Exhibit 52: Chart on Women - Year-over-year growth 2021-2026 (%) - Exhibit 53: Data Table on Women - Year-over-year growth 2021-2026 (%) - 6.4 Men - Market size and forecast 2021-2026 - Exhibit 54: Chart on Men - Market size and forecast 2021-2026 ($ million) - Exhibit 55: Data Table on Men - Market size and forecast 2021-2026 ($ million) - Exhibit 56: Chart on Men - Year-over-year growth 2021-2026 (%) - Exhibit 57: Data Table on Men - Year-over-year growth 2021-2026 (%) - 6.5 Unisex - Market size and forecast 2021-2026 - Exhibit 58: Chart on Unisex - Market size and forecast 2021-2026 ($ million) - Exhibit 59: Data Table on Unisex - Market size and forecast 2021-2026 ($ million) - Exhibit 60: Chart on Unisex - Year-over-year growth 2021-2026 (%) - Exhibit 61: Data Table on Unisex - Year-over-year growth 2021-2026 (%) - 6.6 Market opportunity by End-user - Exhibit 62: Market opportunity by End-user ($ million) 7 Customer Landscape - 7.1 Customer landscape overview - Exhibit 63: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria 8 Geographic Landscape - 8.1 Geographic segmentation - Exhibit 64: Chart on Market share by geography 2021-2026 (%) - Exhibit 65: Data Table on Market share by geography 2021-2026 (%) - 8.2 Geographic comparison - Exhibit 66: Chart on Geographic comparison - Exhibit 67: Data Table on Geographic comparison - 8.3 Europe - Market size and forecast 2021-2026 - Exhibit 68: Chart on Europe - Market size and forecast 2021-2026 ($ million) - Exhibit 69: Data Table on Europe - Market size and forecast 2021-2026 ($ million) - Exhibit 70: Chart on Europe - Year-over-year growth 2021-2026 (%) - Exhibit 71: Data Table on Europe - Year-over-year growth 2021-2026 (%) - 8.4 North America - Market size and forecast 2021-2026 - Exhibit 72: Chart on North America - Market size and forecast 2021-2026 ($ million) - Exhibit 73: Data Table on North America - Market size and forecast 2021-2026 ($ million) - Exhibit 74: Chart on North America - Year-over-year growth 2021-2026 (%) - Exhibit 75: Data Table on North America - Year-over-year growth 2021-2026 (%) - 8.5 APAC - Market size and forecast 2021-2026 - Exhibit 76: Chart on APAC - Market size and forecast 2021-2026 ($ million) - Exhibit 77: Data Table on APAC - Market size and forecast 2021-2026 ($ million) - Exhibit 78: Chart on APAC - Year-over-year growth 2021-2026 (%) - Exhibit 79: Data Table on APAC - Year-over-year growth 2021-2026 (%) - 8.6 South America - Market size and forecast 2021-2026 - Exhibit 80: Chart on South America - Market size and forecast 2021-2026 ($ million) - Exhibit 81: Data Table on South America - Market size and forecast 2021-2026 ($ million) - Exhibit 82: Chart on South America - Year-over-year growth 2021-2026 (%) - Exhibit 83: Data Table on South America - Year-over-year growth 2021-2026 (%) - 8.7 Middle East and Africa - Market size and forecast 2021-2026 - Exhibit 84: Chart on Middle East and Africa - Market size and forecast 2021-2026 ($ million) - Exhibit 85: Data Table on Middle East and Africa - Market size and forecast 2021-2026 ($ million) - Exhibit 86: Chart on Middle East and Africa - Year-over-year growth 2021-2026 (%) - Exhibit 87: Data Table on Middle East and Africa - Year-over-year growth 2021-2026 (%) - 8.8 US - Market size and forecast 2021-2026 - Exhibit 88: Chart on US - Market size and forecast 2021-2026 ($ million) - Exhibit 89: Data Table on US - Market size and forecast 2021-2026 ($ million) - Exhibit 90: Chart on US - Year-over-year growth 2021-2026 (%) - Exhibit 91: Data Table on US - Year-over-year growth 2021-2026 (%) - 8.9 Brazil - Market size and forecast 2021-2026 - Exhibit 92: Chart on Brazil - Market size and forecast 2021-2026 ($ million) - Exhibit 93: Data Table on Brazil - Market size and forecast 2021-2026 ($ million) - Exhibit 94: Chart on Brazil - Year-over-year growth 2021-2026 (%) - Exhibit 95: Data Table on Brazil - Year-over-year growth 2021-2026 (%) - 8.10 Japan - Market size and forecast 2021-2026 - Exhibit 96: Chart on Japan - Market size and forecast 2021-2026 ($ million) - Exhibit 97: Data Table on Japan - Market size and forecast 2021-2026 ($ million) - Exhibit 98: Chart on Japan - Year-over-year growth 2021-2026 (%) - Exhibit 99: Data Table on Japan - Year-over-year growth 2021-2026 (%) - 8.11 UK - Market size and forecast 2021-2026 - Exhibit 100: Chart on UK - Market size and forecast 2021-2026 ($ million) - Exhibit 101: Data Table on UK - Market size and forecast 2021-2026 ($ million) - Exhibit 102: Chart on UK - Year-over-year growth 2021-2026 (%) - Exhibit 103: Data Table on UK - Year-over-year growth 2021-2026 (%) - 8.12 China - Market size and forecast 2021-2026 - Exhibit 104: Chart on China - Market size and forecast 2021-2026 ($ million) - Exhibit 105: Data Table on China - Market size and forecast 2021-2026 ($ million) - Exhibit 106: Chart on China - Year-over-year growth 2021-2026 (%) - Exhibit 107: Data Table on China - Year-over-year growth 2021-2026 (%) - 8.13 Market opportunity by geography - Exhibit 108: Market opportunity by geography ($ million) 9 Drivers, Challenges, and Trends - 9.1 Market drivers - 9.2 Market challenges - 9.3 Impact of drivers and challenges - Exhibit 109: Impact of drivers and challenges in 2021 and 2026 - 9.4 Market trends 10 Vendor Landscape - 10.1 Overview - 10.2 Vendor landscape - Exhibit 110: Overview on Criticality of inputs and Factors of differentiation - 10.3 Landscape disruption - Exhibit 111: Overview on factors of disruption - 10.4 Industry risks - Exhibit 112: Impact of key risks on business 11 Vendor Analysis - 11.1 Vendors covered - Exhibit 113: Vendors covered - 11.2 Market positioning of vendors - Exhibit 114: Matrix on vendor position and classification - 11.3 Amway Corp. - Exhibit 115: Amway Corp. - Overview - Exhibit 116: Amway Corp. - Product / Service - Exhibit 117: Amway Corp. - Key offerings - 11.4 Chatters Ltd. Partnership - Exhibit 118: Chatters Ltd. Partnership - Overview - Exhibit 119: Chatters Ltd. Partnership - Product / Service - Exhibit 120: Chatters Ltd. Partnership - Key offerings - 11.5 Coty Inc. - Exhibit 121: Coty Inc. - Overview - Exhibit 122: Coty Inc. - Business segments - Exhibit 123: Coty Inc. - Key offerings - Exhibit 124: Coty Inc. - Segment focus - 11.6 The Estee Lauder Co. Inc. - Exhibit 125: The Estee Lauder Co. Inc. - Overview - Exhibit 126: The Estee Lauder Co. Inc. - Business segments - Exhibit 127: The Estee Lauder Co. Inc. - Key news - Exhibit 128: The Estee Lauder Co. Inc. - Key offerings - Exhibit 129: The Estee Lauder Co. Inc. - Segment focus - 11.7 Godrej and Boyce Manufacturing Co. Ltd. - Exhibit 130: Godrej and Boyce Manufacturing Co. Ltd. - Overview - Exhibit 131: Godrej and Boyce Manufacturing Co. Ltd. - Business segments - Exhibit 132: Godrej and Boyce Manufacturing Co. Ltd. - Key offerings - Exhibit 133: Godrej and Boyce Manufacturing Co. Ltd. - Segment focus - 11.8 Henkel AG and Co. KGaA - Exhibit 134: Henkel AG and Co. KGaA - Overview - Exhibit 135: Henkel AG and Co. KGaA - Business segments - Exhibit 136: Henkel AG and Co. KGaA - Key news - Exhibit 137: Henkel AG and Co. KGaA - Key offerings - Exhibit 138: Henkel AG and Co. KGaA - Segment focus - 11.9 John Paul Mitchell Systems - Exhibit 139: John Paul Mitchell Systems - Overview - Exhibit 140: John Paul Mitchell Systems - Product / Service - Exhibit 141: John Paul Mitchell Systems - Key offerings - 11.10 Kao Corp. - Exhibit 142: Kao Corp. - Overview - Exhibit 143: Kao Corp. - Business segments - Exhibit 144: Kao Corp. - Key offerings - Exhibit 145: Kao Corp. - Segment focus - 11.11 LOreal SA - Exhibit 146: LOreal SA - Overview - Exhibit 147: LOreal SA - Business segments - Exhibit 148: LOreal SA - Key news - Exhibit 149: LOreal SA - Key offerings - Exhibit 150: LOreal SA - Segment focus - 11.12 Madison Reed Inc. - Exhibit 151: Madison Reed Inc. - Overview - Exhibit 152: Madison Reed Inc. - Product / Service - Exhibit 153: Madison Reed Inc. - Key offerings 12 Appendix - 12.1 Scope of the report - 12.2 Inclusions and exclusions checklist - Exhibit 154: Inclusions checklist - Exhibit 155: Exclusions checklist - 12.3 Currency conversion rates for US$ - Exhibit 156: Currency conversion rates for US$ - 12.4 Research methodology - Exhibit 157: Research methodology - Exhibit 158: Validation techniques employed for market sizing - Exhibit 159: Information sources - 12.5 List of abbreviations - Exhibit 160: List of abbreviations About Us Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contact Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: www.technavio.com/ SOURCE Technavio	https://www.prnewswire.com/news-releases/hair-color-market---30-of-growth-to-originate-from-europe-evolving-opportunities-with-amway-corp--avon--technavio-301562967.html	2022-06-08T12:03:27	en	0.813778
Hamilton Lane to Participate at Morgan Stanley Financials Conference on June 15 CONSHOHOCKEN, Pa., June 8, 2022 /PRNewswire/ --- Hamilton Lane (NASDAQ: HLNE) today announced that Erik Hirsch, Vice Chairman and Head of Strategic Initiatives, will be participating at the 2022 Morgan Stanley US Financials, Payments & CRE Conference on Wednesday, June 15 at 1:00 PM ET. A live audio webcast of the presentation will be available on Hamilton Lane's Shareholders page or by clicking here. For those unable to listen to the live audio webcast of the event, a replay will be available on Hamilton Lane's Shareholders page shortly after the presentation for a period of one year. About Hamilton Lane Hamilton Lane (NASDAQ: HLNE) is a leading private markets investment management firm providing innovative solutions to institutional and private wealth investors around the world. Dedicated exclusively to private markets investing for 30 years, the firm currently employs approximately 530 professionals operating in offices throughout North America, Europe, Asia Pacific and the Middle East. Hamilton Lane has over $901 billion in assets under management and supervision, composed of more than $106 billion in discretionary assets and nearly $795 billion in advisory assets, as of March 31, 2022. Hamilton Lane specializes in building flexible investment programs that provide clients access to the full spectrum of private markets strategies, sectors and geographies. For more information, please visit www.hamiltonlane.com or follow Hamilton Lane on LinkedIn: https://www.linkedin.com/company/hamilton-lane/. SOURCE Hamilton Lane	https://www.prnewswire.com/news-releases/hamilton-lane-to-participate-at-morgan-stanley-financials-conference-on-june-15-301563359.html	2022-06-08T12:03:33	en	0.920605
Huawei Announces New Inventions That Will Revolutionize AI, 5G, and User Experience Company discloses progress in IP, innovation at themed event SHENZHEN, China, June 8, 2022 /PRNewswire/ -- Huawei announced a batch of key inventions as part of its biennial "Top Ten Inventions" Awards at the "Broadening the Innovation Landscape 2022" forum held at its Shenzhen headquarters. The award is designed to recognize inventions that could create new series of products, become important commercial features of existing products, or that generate considerable value for the company and the industry. The awarded inventions range from an adder neural network that significantly reduces power consumption and circuit area to a game-changing "optical iris" that provides a unique identifier for optical fibers. It is designed to help carriers manage their network resources, cutting time and costs associated with broadband deployment. The announcement came in the context of intellectual property rights, the protection and sharing of which Huawei believes is critical to the tech ecosystem. "Protecting IP is key to protecting innovation," said Huawei's Chief Legal Officer, Song Liuping. "We are eager to license our patents and technologies to share our innovations with the world. This will help broaden the innovation landscape, drive our industry forward, and advance technology for everyone," he added. "Huawei is constantly changing itself, and constantly showcasing to the world the value of IP from China," said Tian Lipu, President of the International Association for the Protection of Intellectual Property's China Chapter. By the end of 2021, Huawei held more than 110,000 active patents across over 45,000 patent families. It has more granted patents than any other Chinese company, has filed the most patent applications with the EU Patent Office, and ranked fifth in terms of new patents granted in the United States. For five straight years, Huawei has ranked No. 1 worldwide in terms of Patent Cooperation Treaty applications. Alan Fan, Head of Huawei's IPR Department, said the value of Huawei patents has seen wide recognition in the industry, especially in mainstream standards such as cellular technology, Wi-Fi, and audio/video codecs. "In the past five years, more than two billion smartphones have been licensed to Huawei's 4G/5G patents. And for cars, about eight million connected vehicles licensed to Huawei patents are being delivered to the consumers every year," Fan said. Huawei is also working actively with patent license administration companies in offering "one-stop" licenses for mainstream standards. "Over 260 companies—accounting for one billion devices—have obtained Huawei's HEVC patent licenses through a patent pool," Fan said. He added that the company is in discussions to establish a new patent pool to give the industry "quick access" to Huawei's patents for Wi-Fi devices worldwide. Huawei is also discussing joint licensing programs for 5G patents with licensing experts and other leading industry patentees. Liu Hua, Director of World Intellectual Property Organization Office in China, praised Huawei's sustained focus on innovation, saying: "We look forward to seeing Huawei continue to take part in high-level global competition with innovation at its core." For Manuel Desantes, former Vice President of European Patent Office, given the vast number of changes in the world these days, what matters most is no longer the number of registered patents or inventions. "The IP system should assure that the creations that merit protection are those that bring actual value," he said. This marked the third innovation and IP-themed event Huawei has hosted on its innovation practices. Every year, Huawei invests over 10% of its sales revenue into R&D. In terms of R&D expenditure, Huawei ranked second in the 2021 EU Industrial R&D Investment Scoreboard. In 2021, the company increased its R&D investment to CNY142.7 billion, representing 22.4% of our total revenue. Over the past decade, Huawei's total R&D investment surpassed CNY845 billion. SOURCE Huawei	https://www.prnewswire.com/news-releases/huawei-announces-new-inventions-that-will-revolutionize-ai-5g-and-user-experience-301563881.html	2022-06-08T12:03:39	en	0.954088
At least 17 people were killed and 50 more injured after a passenger train derailed in eastern Iran early Wednesday morning, the Iranian Red Crescent said on Twitter. Twenty-two rescue teams, 10 ambulances and three helicopters were deployed after five train cars derailed at 5.30 a.m. local time near the city of Tabas. The injured were transported to nearby cities for treatment, according to state media. The death toll is expected to rise due to the severity of the injuries, Iranian state media outlet IRNA quoted south Khorasan governorate official Seyyed Abolhassan Mirjalili as saying. The train was carrying 348 passengers when it collided with an excavator on the rail, IRNA said. It had been traveling to the city of Yazd, according to Reuters. Aerial footage published on the Iranian Red CrescentвҖҷs social media showed the cars on their side in the desert. The incident comes almost two weeks after a 10-story commercial building collapsed in the city of Abadan, killing 41 people and sparking anti-government demonstrations across Iranian provinces.	https://www.cnn.com/2022/06/08/middleeast/irain-train-derailment-intl/index.html	2022-06-08T12:03:44	en	0.973065
LONDON, June 8, 2022 /PRNewswire/ -- IHG Hotels & Resorts (IHG), one of the world's leading hotel companies, is celebrating 6,000 open hotels by unveiling the '6,000 Club' and announcing partnerships with major sports and entertainment events. The 6,000 Club features a collection of stunning newly opened hotels from IHG's iconic portfolio, showcasing the global reach of its 17 brands and the many ways its hotel teams delight owners and guests by delivering True Hospitality for Good, every day. The milestone was commemorated by IHG CEO, Keith Barr, at the New York Stock Exchange on June 7 when he rang the bell to signal the close of trading, alongside local hotel General Managers and colleagues. In the past five years, IHG has broadened its appeal to owners and guests by acquiring or launching six exciting brands to take the portfolio to 17 - providing more choice and amazing experiences than ever before. The new additions include Luxury & Lifestyle brands Six Senses, Regent and Vignette Collection; Premium brand, voco hotels; Essentials brand, avid hotels; and Suites brand, Atwell Suites. IHG is set to grow its portfolio by a further 30 percent, with more than 1,800 hotels already signed in its development pipeline, illustrating how much owners value the strength of IHG's scale and brands. To thank guests, the company recently reinvented its loyalty programme, IHG One Rewards, to offer members more choice, value and richer rewards than ever before - all powered by leading technology on a new mobile app. The company is also announcing a series of exciting multi-year sports and entertainment partnerships for IHG One Rewards members that will connect travellers at events around the world, including Major League Soccer, European Professional Club Rugby and music festivals across the US and UK. The partnerships will reward loyal members with the chance to create memorable moments from events the world has missed in recent years. IHG Hotels & Resorts CEO, Keith Barr, said: "I'm incredibly proud of our IHG Hotels & Resorts teams for reaching a milestone of 6,000 hotels open around the world, and would like to thank our owners for their collaboration and our guests for their love and trust in our brands. Every single property we open is a cause for celebration as we offer guests unrivalled experiences in amazing locations and give owners even more reasons to work with us. Our new partnerships will connect more of our IHG One Rewards members with memorable moments, as travel continues to return. With over 1,800 hotels in our pipeline, I'm looking forward to IHG's next chapter of growth and to celebrating plenty more milestones to come." 6,000 Club Hotels in the 6,000 Club will celebrate the occasion in the coming months by surprising select guests with 6,000 IHG One Rewards points. Some of the hotels in the Club are: - Six Senses Fort Barwara – a beautiful 14th-century fort in India which was converted to become a sanctuary of well-being after a significant conservation effort - Regent Phu Quoc – the first all-suites-and-villas resort under the upper luxury brand in Southeast Asia, located off the southwest coast of Vietnam alongside a UNESCO-designated World Biosphere Reserve - Kimpton Margot Sydney – marking the Australian debut for the brand, this art-deco hotel features a rooftop pool, wine bar, and a 1,725-square-foot "Celebrity Suite" - voco The Hague – the first for the brand in Netherlands which includes a garden terrace designed by an expert ecologist who created a welcoming space for nature to thrive - Atwell Suites Denver Airport - Tower Road – the second hotel to open for IHG's newest all-suites brand, featuring the brand's signature design and adaptable spaces which support longer stays and allow for easy transition between business and leisure - Staybridge Suites Al Khobar City – the second for the brand in Saudi Arabia, this all-suites hotel is located on the shores of the Arabian Gulf in the heart of the corporate and shopping hub of vibrant Al Khobar For the complete list of the 6,000 Club, please click here. IHG Partnerships With a shared belief that experiences bring people together, the new partnerships will connect travellers around the world. Each national partnership will bring people together by creating new ways to redeem IHG One Rewards points and celebrate the universal love of music and sports. Highlights include: - The Governors Ball, Lollapalooza, Reading and Leeds Festivals, Music Midtown, Ohana Festival: While watching live performances, attendees can enjoy exclusive benefits with IHG One Rewards including backstage access and time in VIP Lounges. - Major League Soccer: With a multi-year agreement as the official hotel sponsor, IHG Hotels & Resorts and MLS are partnering to create unique, enhanced money-can't-buy experiences exclusively for IHG One Rewards members and MLS fans across the country. - European Professional Club Rugby (EPCR): With the Heineken Champions Cup and EPCR Challenge Cup 2021/2022 tournaments ending in May, under this three-season agreement IHG and EPCR will welcome fans back at the start of the 2022/2023 season beginning this December. To learn more about IHG Hotels & Resorts, visit here. About IHG Hotels & Resorts IHG Hotels & Resorts [LON:IHG,NYSE:IHG (ADRs)] is a global hospitality company, with a purpose to provide True Hospitality for Good. With a family of 17 hotel brands and IHG One Rewards, one of the world's largest hotel loyalty programmes, IHG has over 6,000 open hotels in over 100 countries, and more than 1,800 in the development pipeline. - Luxury & Lifestyle: Six Senses Hotels Resorts Spas, Regent Hotels & Resorts, InterContinental Hotels & Resorts, Vignette Collection, Kimpton Hotels & Restaurants, Hotel Indigo - Premium: voco hotels, HUALUXE Hotels & Resorts, Crowne Plaza Hotels & Resorts, EVEN Hotels - Essentials: Holiday Inn Hotels & Resorts, Holiday Inn Express, avid hotels - Suites: Atwell Suites, Staybridge Suites, Holiday Inn Club Vacations, Candlewood Suites InterContinental Hotels Group PLC is the Group's holding company and is incorporated and registered in England and Wales. Approximately 325,000 people work across IHG's hotels and corporate offices globally. Visit us online for more about our hotels and reservations and IHG One Rewards. For our latest news, visit our Newsroom and follow us on LinkedIn, Facebook and Twitter. SOURCE IHG Hotels & Resorts	https://www.prnewswire.com/news-releases/ihg-hotels--resorts-marks-6-000-hotels-milestone-with-spectacular-openings-and-partnerships-to-reward-travellers-301563636.html	2022-06-08T12:03:46	en	0.929393
podcast Tug of War Tug of War takes listeners to the most volatile corners of the world where democracy is in its dying days. In a special ongoing season, CNN reporters take us on-the-ground in Ukraine to document Russia’s invasion, the escalating conflict, and what it means for the rest of the world. 100 Days Later, Ukraine’s Fight Continues Tug of War He was in Kyiv at the very start of the invasion - CNN Senior International correspondent Matthew Chance returns to find a city experiencing an uneasy calm. Meanwhile, brutal fighting continues in the South and East as the Ukrainians go on a counter-offensive, hoping to retake Russian-occupied territory. We examine what life is like for everyday Ukrainians who have returned to horror and look at what comes next as the conflict drags on. Recorded on June 3, 2022. Recorded on June 3, 2022. Jun 8, 2022	https://www.cnn.com/audio/podcasts/tug-of-war/episodes/b69410c8-ebe3-4fc9-b817-aeae00024904	2022-06-08T12:03:50	en	0.939291
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Indonesia's G20 HWG Meeting Series Urges World Leaders to Be Prepared for Future Pandemics LOMBOK, Indonesia, June 8, 2022 /PRNewswire/ -- The second Health Working Group (HWG) meeting brought global leaders to initiate a new global emergency fund for future pandemics and focused on facilitating greater sharing of genomic sequencing data, as well as how the Financing Intermediary Fund (FIF) functions under the World bank in preparing for future pandemics. The Indonesian Health Minister, Budi Gunadi Sadikin, encouraged the G20 member states not let pandemic stride without learning valuable lessons. "Only through great earthquakes, lofty mountains rise. I believe this is true, not only for volcanoes, but also for our humanity. During every crisis, lie great opportunities," said in Lombok, West Nusa Tenggara, Indonesia. The main issues addressed in the 6 to 8 June 2022 meeting were mobilization of financial resources for future pandemic responses. G20 member states discussed lessons learned from the successes of medical countermeasures initiatives, such as COVAX and the ACT-accelerators that worked efficiently during the pandemic in ushering vaccines, therapeutics, and diagnostics. G20 and its partners, such as GISAID, now is looking at the optimization of genomic surveillance and trusted data sharing mechanisms, allowing the world to quickly identify novel pathogens that may pose new threats to global health security. "We need a more permanent coordinating platform that can address five cores such as access to countermeasures, emergency coordination, collaborative intelligence, community protection; and clinical care to patients in need," said the Minister of Health. Indonesia has committed to donate USD50 million to the FIF. As part of the G20 presidency mandate, Indonesia will also lobby organizations and donors to ensure that the fund benefit the right target countries to prevent conflicting interests from donors and organizations. Dr. Tedros Adhanom Ghebreyesus, WHO's General Secretary, was commended Indonesia's presidency to prioritize the establishment of global health system architecture and putting it in the G20 agenda. "We must learn from the lessons this pandemic has taught us because this will not be the last one," said Dr. Tedros. To access the Health Working Group plenary opening ceremony and press conference, visit https://www.youtube.com/c/KementerianKesehatanRI. SOURCE The Indonesian Ministry of Health	https://www.prnewswire.com/news-releases/indonesias-g20-hwg-meeting-series-urges-world-leaders-to-be-prepared-for-future-pandemics-301563915.html	2022-06-08T12:03:52	en	0.937295
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BOSTON, June 8, 2022 /PRNewswire/ -- Ropes & Gray today announced the appointment of Hui Chen as senior advisor in its innovative R&G Insights Lab, the legal industry's first analytics and behavioral science consulting group. Hui Chen is an internationally renowned expert in business ethics and compliance, and a long-time—and early—advocate of data-driven compliance and the use of multidisciplinary teams to tackle ethics and compliance challenges. She brings to R&G Insights Lab decades of experience as a government prosecutor and expert consultant, in-house compliance executive, academic researcher, and ethics and compliance thought leader. She has served with distinction in business, academia, and government, including as the first in-house compliance counsel expert at the U.S. Department of Justice (DOJ). "Hui is a one-of-a-kind talent," said Zachary Coseglia, co-founder and managing principal of R&G Insights Lab. "She has extensive inside regulatory knowledge and deep cross-industry relationships; she is also intensely analytical, wonderfully creative, and purposefully practical. Her contributions to ethics and compliance are unmatched. She has, put simply, helped shape many of the best practices that now define these disciplines." While at DOJ, Hui advised prosecutors in the DOJ's Fraud Section on corporate ethics and compliance. She was also the architect of the DOJ's Evaluation of Corporate Compliance Programs guidance document, the now "go-to" guide for compliance practitioners across industries and geographies. But her experience is deep, and her knowledge is broad -- extending far beyond traditional areas of ethics and compliance. "Few lawyers have Hui's experience, and by extension, credibility, in the regulatory and enforcement sphere," said litigation & enforcement partner Amanda Raad, co-founder of the Lab and global co-leader of the firm's anticorruption and international risk practice. "Her work and influence sits at the intersection of risk, ESG, enforcement, and investigations, and will elevate R&G Insights Lab's efforts on behalf of Ropes & Gray clients worldwide." Hui began her career as a federal prosecutor under the Attorney General's Honors Program at DOJ. She then served as an Assistant U.S. Attorney in the Eastern District of New York, where she represented the U.S. in federal criminal cases involving narcotics, terrorism, and fraud. She has held high-profile, in-house compliance positions at Microsoft, Pfizer and Standard Chartered Bank. Hui was also the first foreign expert consultant to the Brazilian Comptroller General of the Union; and has frequently provided trainings and presentations to prosecutors and regulators in the U.S., Europe, Latin America, and Asia. Hui has experience in and has advised on a range of legal and compliance topics, including anti-bribery and corruption; discrimination and harassment; antitrust and competition compliance; sanctions and money laundering; privacy and data governance; environmental compliance; and intellectual property. "R&G Insights Lab is groundbreaking and innovative," said Hui Chen, senior advisor, R&G Insights Lab. "It is the realization of everything I believe about how ethics and compliance should be done. Data- and science-driven; out-comes focused; and interdisciplinary." About R&G Insights Lab R&G Insights Lab is the legal industry's first – and only – analytics and behavioral science consulting group. The Lab takes a data-driven and human-centered approach to solving complex legal and business challenges. Staffed by a multidisciplinary global team, the Lab uses analytics to measure outcomes and drive informed decision-making; behavioral science to understand organizational culture and confront the realities of human bias; and the principles of human-centered design to develop creative client solutions. Areas of focus include compliance, ethics, and risk management; organizational culture; diversity, equity and inclusion; ESG; and other areas of corporate social responsibility. The Lab advises clients across a range of industries, including private equity, health care, life sciences, and technology. About Ropes & Gray Ropes & Gray is a preeminent global law firm with approximately 1,400 lawyers and legal professionals serving clients in major centers of business, finance, technology, and government. The firm has offices in New York, Boston, Washington, D.C., Chicago, Los Angeles, San Francisco, Silicon Valley, London, Hong Kong, Shanghai, Tokyo, and Seoul, and has consistently been recognized for its leading practices in many areas, including private equity, M&A, finance, asset management, real estate, tax, antitrust, life sciences, health care, intellectual property, litigation & enforcement, privacy & cybersecurity, and business restructuring. Website \| LinkedIn \| Twitter \| Videos \| Podcasts To view our privacy policy, please click here. Contact: Aaron Kellogg +1 617 235 4403 [email protected] SOURCE Ropes & Gray	https://www.prnewswire.com/news-releases/internationally-renowned-ethics-expert-hui-chen-joins-rg-insights-lab-301563891.html	2022-06-08T12:03:58	en	0.947226
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"Pause Pain and Wellness Medical Cannabis Clinics certainly are." -- Kirk L. Kinard, DO OXFORD, Miss., June 8, 2022 /PRNewswire/ -- "Pause Pain and Wellness Medical Cannabis Clinics certainly are," says spokesperson and owner Kirk L. Kinard, DO of Oxford, MS who has teamed with his pain management colleagues throughout the state to open clinics solely dedicated to the evaluation and education of patients considering this much-anticipated alternative to traditional pain medications. The medical cannabis ballot initiative of the November 2020 election cycle received overwhelming support from over 70% of the Mississippi voting public, and the legislature heard them loud and clear by stamping their approval with Senate Bill 2095, the Mississippi Medical Cannabis Act, which was signed into law earlier this year. Mississippi asked and has now received, but "we are a conservative state, and many are still predictably cautious, if not skeptical, of the whole idea," says Kinard. That reservation is exactly what sparked the idea to offer dedicated outlets for patients and medical providers alike. Most of the debilitating medical conditions which currently allow a patient to be eligible for a medical marijuana card are related to chronic pain, which is a very challenging disease requiring attention to both the physical and emotional consequences of those suffering from its grip. A weekly report from the CDC in 2018 cited the following: "Chronic pain, one of the most common reasons adults seek medical care, has been linked to restrictions in mobility and daily activities, dependence on opioids, anxiety and depression, and poor perceived health or reduced quality of life." Pause Pain and Wellness clinics will utilize collaborating physicians in metropolitan locations throughout the state with specialty training and board certification in the field of pain medicine. "There are no better equipped physician-led teams to evaluate and manage this patient population with medical cannabis than those already with years of experience doing so," says Kinard, who has seen the limitations of even the most specialized procedures and medications for many chronic pain patients in his almost 15 years of practicing pain management in north Mississippi. "Medical marijuana will be a welcomed option for many patients but, like any other prescription medication, patient selection and careful monitoring and education are certainly warranted to ensure its safe use." Pause Pain & Wellness exists to provide focused and compassionate care to patients throughout the state of Mississippi using an evidence-based application of medical cannabis research. As the only clinic with statewide locations, Pause Pain & Wellness goes above and beyond to keep patients in compliance with Mississippi law so they can keep their cards for as long as they need them. It's Time to Pause the Pain. Media Contact: Robert Gammons [email protected] Mississippi medical marijuana, Mississippi marijuana laws This press release was issued through 24-7PressRelease.com. For further information, visit http://www.24-7pressrelease.com. SOURCE Pause Pain & Wellness	https://www.prnewswire.com/news-releases/is-mississippi-ready-for-medical-marijuana-301563361.html	2022-06-08T12:04:04	en	0.962225
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Key project in Jacobs' growing transport infrastructure portfolio in Asia DALLAS, June 8, 2022 /PRNewswire/ -- Jacobs (NYSE:J) has been appointed as the design consultant for the design and construction of the Tavistock Station and Tunnels, as part of the Cross Island Line Phase 1 project in Singapore. Constructed in three phases, the Cross Island Line is Singapore's eighth Mass Rapid Transit (MRT) line with the longest fully underground network. It will serve existing and future developments in the eastern, north-eastern and western corridors – linking major hubs and interchanges and make commuting across the rail network more convenient and efficient. The contract is valued at approximately $302 million (SGD$407 million) and comprises the design and construction of the underground station, bored tunnels, launching shaft for tunnel boring machines and associated building services. "This appointment builds on Jacobs' strong track record of delivering transformational projects in Singapore, as well as strengthening our presence in the growing transport infrastructure market across Asia," said Jacobs People & Places Solutions Senior Vice President Keith Lawson. "Our technical skills and rail experience will help connect more people, places and communities in this vibrant city and support our goal of creating a more connected, sustainable world." Jacobs will work with Sato Kogyo, which was awarded the contract by Singapore's Land Transport Authority, to provide civil, structural and architectural design services and maintain critical oversight through to the construction of the project. The Cross Island Line Phase 1 comprises 12 stations, including the Tavistock Station and will serve residential and industrial areas in Loyang, Tampines, Pasir Ris, Defu, Hougang, Serangoon North and Ang Mo Kio. The 29-kilometer MRT line will benefit more than 100,000 households and provide greater accessibility for common recreational spaces such as Changi Beach Park and Bishan-Ang Mo Kio Park. Construction for Tavistock station began in May with passenger service for Cross Island Line Phase 1 slated to commence in 2030. At Jacobs, we're challenging today to reinvent tomorrow by solving the world's most critical problems for thriving cities, resilient environments, mission-critical outcomes, operational advancement, scientific discovery and cutting-edge manufacturing, turning abstract ideas into realities that transform the world for good. With $14 billion in revenue and a talent force of approximately 55,000, Jacobs provides a full spectrum of professional services including consulting, technical, scientific and project delivery for the government and private sector. Visit jacobs.com and connect with Jacobs on Facebook, Instagram, LinkedIn and Twitter. Certain statements contained in this press release constitute forward-looking statements as such term is defined in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such statements are intended to be covered by the safe harbor provided by the same. Statements made in this release that are not based on historical fact are forward-looking statements. When used herein, words such as "expects," "anticipates," "believes," "seeks," "estimates," "plans," "intends," "future," "will," "would," "could," "can," "may," and similar words are intended to identify forward-looking statements. We base these forward-looking statements on management's current estimates and expectations as well as currently available competitive, financial and economic data. Forward-looking statements, however, are inherently uncertain. There are a variety of factors that could cause business results to differ materially from our forward-looking statements, including, but not limited to, the timing of the award of projects and funding under the Infrastructure Investment and Jobs Act as well as general economic conditions, including inflation, changes in interest rates, foreign currency exchange rates, and changes in capital markets, geopolitical events and conflicts, and the impact of the COVID-19 pandemic, including the related reaction of governments on global and regional market conditions and the company's business, among others. For a description of some additional factors that may occur that could cause actual results to differ from our forward-looking statements, see the discussions contained under Item 1 - Business; Item 1A - Risk Factors; Item 3 - Legal Proceedings; and Item 7 - Management's Discussion and Analysis of Financial Condition and Results of Operations in our most recently filed Annual Report on Form 10-K, ,and Item 2 - Management's Discussion and Analysis of Financial Condition and Results of Operations; Item 1 - Legal Proceedings; and Item 1A - Risk Factors in our most recently filed Quarterly Report on Form 10-Q, as well as the company's other filings with the Securities and Exchange Commission. The company is not under any duty to update any of the forward-looking statements after the date of this press release to conform to actual results, except as required by applicable law. For press/media inquiries: Kerrie Sparks 214.583.8433 SOURCE Jacobs	https://www.prnewswire.com/news-releases/jacobs-secures-rail-contract-in-singapore-301563740.html	2022-06-08T12:04:10	en	0.95542
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Lingnan University study finds older adults show greater resilience during COVID-19 pandemic HONG KONG, June 8, 2022 /PRNewswire/ -- People have been forced to adapt to the new normal in the wake of the COVID-19 outbreak. Evidence suggests that people's subjective well-being has deteriorated especially in societies where the negative impact of the pandemic is relatively large. However, a recent study conducted by Lingnan University (LU) in Hong Kong reveals that Japanese older adults' life satisfaction, as compared with their younger counterparts, had substantially improved during the pandemic, indicating their resilience on average. This research analysed the data from a nationwide panel survey "Changes in Attitudes and Behaviors during the COVID-19 Pandemic" conducted by the Cabinet Office of the Government of Japan between May 2020 and October 2021 for 3,725 respondents aged 25 and over. Participants had been asked how satisfied with their life by using the Cantril Ladder, with 0 being the worst (i.e., not satisfied at all) and 10 being the best (i.e., extremely satisfied). The shift in life satisfaction was compared across three age groups: 25 to 44; 45 to 64; and 65 and above. Figure 1 summarises the mean scores of life satisfaction across three age groups at the two waves of studies. The results showed that the average life satisfaction had not declined but improved regardless of age during the period. In particular, older adults aged 65 and above showed a substantial gain in life satisfaction throughout the period (mean score raised from 4.56 to 5.57). The results also revealed that older adults' life satisfaction was significantly associated with their socio-economic attributes such as gender, income, health and family/social relationships. It is particularly noteworthy that, while better health and social ties largely demonstrated positive signs for preferable life satisfaction shifts during the two waves of studies (e.g., from low to high and from mid to high) and negative ones for unfavourable combinations (e.g., from low to low and from mid to low), the top income group showed a high probability of obtaining high life satisfaction in both waves (i.e., from high to high). This suggested the possession of financial resources played an essential role in dividing older adults into those who could and who could not retain positive feelings during the pandemic. Meanwhile, it was also found that women were more likely to report the "low to low" combination, implying that older women had been penalised in terms of life satisfaction under COVID-19 despite the observed resilience on average in the same age group. Prof Satoshi Araki, Assistant Professor of the Department of Sociology and Social Policy of Lingnan University in Hong Kong, says that this study should be applicable to other Asian societies including Hong Kong. "Considering that older adults' resilience during the COVID-19 pandemic has been reported worldwide even in the super-aged society Japan, it is logical to assume a similar structure exists in Hong Kong. Meanwhile, there is also a possibility that Hong Kong suffers a relatively larger extent of 'resilience divide' among older adults given the existing socio-economic inequality," he said. To address this pressing social issue and realise human flourishing in an ageing society like Hong Kong, Prof Araki added that multiple stakeholders such as policymakers, practitioners, and researchers must work together to reveal the distribution of socio-economic resources and resilience, thus fostering social policy and practice to support older adults, especially with disadvantaged backgrounds. It is also essential for the government or research bodies to collect high-quality panel data that permit both cross-sectional and longitudinal analyses. This study was published in the Journal of Applied Gerontology (https://doi.org/10.1177/07334648221089284). SOURCE Lingnan University (LU)	https://www.prnewswire.com/news-releases/lingnan-university-study-finds-older-adults-show-greater-resilience-during-covid-19-pandemic-301563908.html	2022-06-08T12:04:16	en	0.965795
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(WXYZ) — Dozens of sexual abuse survivors at the hands of former U.S Gymnastics team doctor Larry Nassar have filed a Collective Administrative Claim against the FBI for its alleged mishandling of credible complaints of sexual assaults by Nassar in July 2015. More than 90 young women and girls are a part of the claim, including Olympic medalists and Team USA gymnasts Simone Biles, Aly Raisman, McKayla Maroney, and Maggie Nichols. Former University of Michigan gymnast Samantha Roy is also part of the group, as is Kaylee Lorincz. The women claim that the FBI failed to protect them from Nassar's abuse despite having the information and authority. They are seeking more than $1 billion from the FBI over the mishandling of the investigation. Under federal law, a government agency has six months to respond to the tort claim. Depending on how the bureau responds, lawsuits could follow. In May, the Justice Department said that it would not pursue criminal charges against former agents who failed to open an investigation quickly. Last month, 13 Nassar survivors filed a lawsuit against the FBI seeking $10 million each, claiming a bungled investigation by federal agents led to more abuse by the sports doctor. Nichols, who was the first victim to speak out against Nassar in 2015, says the FBI instead worked to hide the abuse. “The FBI knew that Larry Nassar was a danger to children when his abuse of me was first reported in September of 2015. For 421 days, they worked with USA Gymnastics and USOPC to hide this information from the public and allowed Nassar to continue molesting young women and girls. It is time for the FBI to be held accountable,” Nichols said. In sworn testimony to Congress, FBI officials admitted that FBI employees failed to perform their basic duties and ethical obligations properly. “People at the FBI had their own chance to stop this monster back in 2015 and failed,” FBI Director Christopher Wray said to Congress. As a result, Nassar continued his predatory behavior, sexually assaulting approximately 90 young women and children between July 28, 2015, and September 12, 2016. “My fellow survivors and I were betrayed by every institution that was supposed to protect us. The US Olympic Committee, USA Gymnastics, the FBI, and now the Department of Justice. I had some hope that they would keep their word and hold the FBI accountable after we poured out our hearts to the US Senate Judiciary Committee and begged for justice. It is clear that the only path to justice and healing is through the legal process,” Maroney said. The claimants are represented by Manly Stewart & Finaldi, Pitt McGehee Palmer Bonanni & Rivers, Grewal Law and Drew, Cooper & Anding, and Gruel Mills. This article was written by WXYZ.	https://www.wsfltv.com/news/national/90-nassar-survivors-seek-more-than-1b-from-fbi-over-handling-of-investigation	2022-06-08T12:04:22	en	0.9766
- All-New Sequoia Builds Upon Three-Row Toyota SUV Heritage - Capstone Luxury Grade Leads Extensive Lineup of Full-Size SUVs - Impressive 437 hp, 583 lb.-ft. of Torque - Maximum Towing Capacity of up to 9,520 lbs. - Assembled in the U.S. at Toyota Motor Manufacturing, Texas in San Antonio - On Sale Late Summer 2022 - Starting MSRP of $58,300 PLANO, Texas, June 8, 2022 /PRNewswire/ -- The all-new 2023 Toyota Sequoia lives up to its powerful and legendary namesake, thanks to a head-turning new look, luxurious comfort, impressive technology and the perfect blend of performance and efficiency. Coupled with Toyota's long-lasting quality, durability and reliability, the three-row SUV is sure to stand tall in the large-size SUV segment when it hits dealerships at the end of the summer with a Manufacturer's Suggested Retail Pricing (MSRP) starting at $58,300. "We are excited to write the next chapter in our truck family story with the all-new 2023 Sequoia," said Joe Moses, general manager of Toyota's Vehicle Marketing Team. "A three-row SUV must be excellent at many things to succeed in this highly competitive market, and we've got that with Sequoia. Our customers will have room for their whole crew, the technology they want to stay connected, and the heavy-duty power and efficiency they need for both on and off road." The third-generation Sequoia is completely redesigned and worthy of the "all-new SUV" description. All 2023 Sequoia will feature the powerful twin-turbo V6 hybrid i-FORCE MAX powertrain. First unveiled on Tundra, this exceptional hybrid produces 437 horsepower and 583 lb.-ft. of torque. The i-FORCE MAX is a cleverly engineered powertrain featuring a unique motor generator within the bell housing between the twin-turbo engine and the 10-speed automatic transmission. This design combines maximum performance with amazing efficiency, and it is built with heavy-duty performance in mind. Sequoia's fuel economy is expected to be extremely competitive at the top of the segment – and a huge improvement over the previous generation. The full-size SUV segment demands a lot, which means the all-new 2023 Sequoia needs to handle – and succeed – at a multitude of tasks. Built with this in mind, the Sequoia is rooted in a modern body-on-frame chassis with a fully boxed frame that shares architecture with the all-new Tundra and all-new global Land Cruiser (which shares its platform with the Lexus LX). The core objective of this platform is to provide excellent handling, supreme comfort and impressive capability. The engineering team behind this next-generation frame was able to increase rigidity and improve ride comfort by using new techniques, such as new laser welding technology that helps reduce mass and weight in areas it's not needed while reinforcing the areas that need them most. Sequoia features an independent front suspension and adopts a new rack-mounted electronic power steering system for improved steering feel. A modern multi-link rear suspension is employed out back to offer a smooth ride and create opportunity to add the available Load-Leveling Rear Height Control Air Suspension and Adaptive Variable Suspension (AVS) for those looking to tow regularly. The three-row SUV offers a range of configurations for seating and cargo. Depending upon the grade, second-row passengers get bench seating or captain's chairs, either of which recline for passenger comfort or fold down/tumble forward if larger cargo space is needed. The third-row passengers benefit from a spacious reclining backseat with available power folding, but the third row also gets one of the most noteworthy new features on Sequoia: the exclusive Sliding Third Row with Adjustable Cargo Shelf System. This segment-first feature allows the third row to slide with 6 inches of adjustment range. The third row can also fold down to complement the different storage positions of the new Adjustable Cargo Shelf System, a removeable shelf that can be set in a variety of storage positions depending upon the situation. The Cargo Shelf System offers the ultimate flexibility in rear cargo and storage needs. Since full-size SUVs need to do it all, towing – whether it be a trailer, boat or RV – is high on that list of demands. That's why the all-new Sequoia offers up to an impressive 9,500-pound maximum towing capacity, a 28 percent increase over the previous generation model. Towing can be an intimidating proposition for some drivers. Not to worry, thanks to impressive technology available on Sequoia. The Tow Tech Package, standard on TRD Pro and Capstone and available on all other grades, offers a suite of features that include Trailer Backup Guide to aid in backing up the SUV with a trailer, and Straight Path Assist, which helps provide steering control to keep the trailer straight on its intended path when backing up. Drive Mode Select is an all-new feature on Sequoia offering different driving modes depending upon driver preference, and it includes standard settings Eco, Normal and Sport. With available Load-Leveling Rear Height Control Air Suspension and Adaptive Variable Suspension, settings expand to include Comfort, Sport S+ and Custom. Using the SPORT or SPORT S+ settings, for example, the i-FORCE MAX powertrain makes use of the electric motor's instantaneous responsiveness. While the electric motor does the bulk of the work at lower speeds, once above 18 mph, the gasoline engine assumes primary operation for excellent performance in the mid- and high-speed range. When in TOW/HAUL mode, the i-FORCE MAX system is constantly in tandem operation to provide impressive acceleration and torque for towing. The view around this stunning SUV is improved as well due to Sequoia's plethora of cameras, displaying multiple exterior angles that are viewable from the available 14-inch touchscreen or the available digital display rearview mirror. Those trailering will appreciate Panoramic View Monitor, which displays a top-down view of the SUV and its surrounding area. Options include a rear split view to show what's nearby on each side of the trailer, and a hitch view to assist with connecting a trailer. For the first time on Sequoia, factory available power folding, extending and retracting tow mirrors can provide added peace. Sequoia offers space for families who need it – whether that be to haul passengers, gear or both. It will be available in five unique grades that include SR5, Limited, Platinum, TRD Pro and the new Capstone grade. Sequoia's grade lineup starts with the well-equipped SR5 that offers a strong foundation of power, efficiency and technology. It touts impressive standard features that include the i-FORCE MAX powertrain that is mated to the standard 10-speed automatic transmission, standard Toyota Safety Sense 2.5, moonroof, heated seats and more. It also features a standard 12.3-inch digital instrument display and Panoramic View Monitor (PVM). When upgrading to the SR5 Premium package, Sequoia adds the 14-inch Toyota Audio Multimedia display, power third row, hands-free liftgate, SofTex-trimmed seats, and cabin and cargo 120-volt power outlets. Also available on SR5 models is the TRD Sport package, which upgrades the standard 18-inch wheels to 20-inch matte black TRD wheels. To complement sporty handling, it adds TRD sport-tuned Bilstein® monotube shocks, TRD-tuned springs, aluminum pedals and a red TRD push-button start. Limited builds upon the SR5 with an emphasis on added convenience. Not only does it gain a standard 14-inch Toyota Audio Multimedia touchscreen, but it also adds standard heated/ventilated front seats with memory settings, standard heated steering wheel, power-folding third row and a hands-free power liftgate. Limited also receives standard second- and third-row manual sunshades to help keep the back half of the SUV sun-free. Available for both SR5 and Limited 4x4 models is the first-for-Sequoia TRD Off-Road package. This package enhances off-road capability with the addition of a selectable locking rear differential, Multi-Terrain Select that helps controls wheel spin for improved traction, and Downhill Assist Control to aid with steep descents. Crawl Control also comes standard, functioning as an off-road cruise control for low-speed trail navigation in 4WD Low. TRD Off-Road also comes with Multi-Terrain Monitor to provide the driver a better view of hard-to-see spots on the trail. TRD-tuned Bilstein® monotube shock absorbers and TRD-tuned springs are added, and a red front axle driveshaft provides added flair. Inside, aluminum gas/brake pedals are included, and a red TRD push-button start button adds to the performance look and feel. Both SR5 and Limited are outfitted with unique 18-inch alloy wheels unique to the package. Stepping up to the Platinum grade puts an emphasis on added comfort and premium features, thanks to heated and ventilated front and second-row, second-row captain's chairs, standard 14-speaker JBL® Premium Audio system, standard panoramic moonroof, standard Head-Up Display and more. High-grade LED headlights and taillights are added, along with sequential turn signals. Rain-sensing wipers are added to Platinum, as is standard Qi wireless charging. TRD Pro is a great option for adventure-minded families that plan to get off the beaten path regularly. TRD Pro is not just an off-roader though, as it is loaded with premium features such as standard second-row captain's chairs, TRD heated steering wheel, and TRD accents on the seats and shift knob. TRD Pro comes with additional cargo hauling options thanks to the TRD roof rack. TRD-tuned FOX internal bypass shocks offer a smooth on-road ride, but most importantly they can confidently handle off-road terrain when the trail gets rough. A 1/4-inch aluminum TRD front skid plate offers added trail protection. Sequoia TRD Pro also offers additional trail capability with a standard selectable locking rear differential, Multi-Terrain Select, CRAWL Control and Downhill Assist Control. TRD Pro proudly sports a heritage-inspired "TOYOTA" grille with an embedded TRD light bar and marker lights toward the top of the grille. It's equipped with Pro-specific black 18-inch TRD alloy wheels with an increased offset to provide a wider stance. A dual TRD Pro exhaust tip provides added growl and visual appeal. The Capstone grade sits atop the Sequoia lineup, building upon the great features of Platinum while adding additional top-shelf features to make it the most luxurious Sequoia to date. Capstone features unique chrome accents to provide an upscale appearance, with the most eye-catching feature being the standard 22-inch chrome wheels – a first for Sequoia and exclusive to Capstone. The premium cabin experience begins at the first step with standard power running boards that provide access to the standard semi-aniline leather-trimmed seats. Not only are the seats luxury-grade, but they also tout stylish perforation and a Capstone-exclusive black-and-white color combination. The center console and passenger-side dash are accented with authentic American Walnut with an open-pore finish that highlights the wood grain. On the dash, the Walnut pieces surround a Capstone logo that is accentuated with LED mood lighting when the doors are opened. For an even quieter cabin, Capstone is the only Sequoia grade to feature acoustic glass in the front doors for more exterior sound deadening. A wide variety of colors are available on the all-new Sequoia, including White, Wind Chill Pearl, Celestial Silver, Lunar Rock, Magnetic Gray Metallic, Blueprint, Army Green, Midnight Black Metallic, Smoked Mesquite, Supersonic Red and the TRD-exclusive Solar Octane. Premium paint colors* Wind Chill Pearl and Supersonic Red are available, and the premium color Solar Octane is exclusive to TRD Pro models. Premium paint colors will be available for an additional cost. Sequoia will be fitted with the new multimedia system first launched in Tundra. It is headlined by large 8-inch or available 14-inch touchscreen that controls the all-new Toyota Audio Multimedia system designed and engineered by Toyota's Texas-based Connected Technologies team. The Toyota Audio Multimedia system offers an improved user experience thanks to new sight, touch, and voice activation. With Intelligent Assistant available through Drive Connect, simple phrases like "Hey Toyota" awakens the system for voice-activated commands to search for directions, find POIs, adjust audio controls, change the cabin temperatures and more. The cloud-based native navigation system offered through Drive Connect allows for real-time Over the Air updates for mapping and Points of Interest (POI), and Google POI data is integrated to ensure up-to-date search capability. It also supports standard wireless Apple CarPlay® and Android Auto compatibility. Toyota Audio Multimedia allows for simultaneous dual Bluetooth phone connectivity. A Wi-Fi Connect subscription offers 4G connectivity for up to 5 devices by turning Sequoia into an AT&T Hotspot, and it also offers the ability to link your separate Apple Music® and Amazon Music subscriptions to your vehicle with Integrated Streaming. All Sequoia grades come standard with Toyota Safety Sense 2.5. This active safety system includes Pre-Collision System with Pedestrian Detection that features multiple enhancements over the previous generation, including not only detecting the vehicle ahead but also a pedestrian in low light, bicyclist in daytime, an oncoming vehicle and a pedestrian at intersections when making a turn. At intersections, the system is designed to detect an oncoming vehicle or pedestrian when performing a left-hand turn and provide audio/visual alerts and automatic braking in certain conditions. Emergency steering assist is an additional function designed to detect pedestrians and stabilize the driver's emergency evasive steering maneuvers and help prevent lane departure. Sequoia will be equipped with Dynamic Radar Cruise Control (DRCC). Lane Departure Alert with Steering Assist is designed to notify the driver via audible and visual alerts and slight steering force if it senses the vehicle is leaving the lane without engaging a turn signal. When DRCC is set and engaged, Lane Tracing Assist uses visible lane markers or a preceding vehicle to help keep the vehicle centered in its lane. Automatic High Beams are designed to detect preceding or oncoming vehicles and automatically switch between high beam and low beam headlights. Road Sign Assist is designed to recognize certain road sign information using a forward-facing camera and display them on the multi-information display (MID). Toyota's Rear Seat Reminder comes standard on all 2023 Sequoias. The feature can note whether a rear door was opened within 10 minutes of the vehicle being turned on, or at any time after the vehicle has been turned on, with a reminder message in the instrument cluster after the engine is turned off, accompanied by multitone chimes. In addition to the TSS 2.5 system, other standard safety features include Blind Spot Monitor which is designed to help detect and warn you of vehicles approaching or positioned in the adjacent lanes. Rear Cross Traffic Alert can offer added peace of mind by helping to detect vehicles approaching from either side while backing out and alerting you with a visual and audible warning. The Front and Rear Parking Assist with Automatic Braking is designed to implement brake control when there's a possibility of a collision with a stationary object, approaching vehicle, or while parking. Toyota's 36-month/36,000-mile basic new-vehicle warranty applies to all components other than normal wear and maintenance items. Additional 60-month warranties cover the powertrain for 60,000 miles and corrosion with no mileage limitation. Hybrid-related components, including the battery control module, hybrid control module and inverter with converter, are covered for 8 years or 100,000 miles, whichever comes first. The hybrid battery is covered for 10 years or 150,000 miles, whichever comes first. Toyota dealers have complete details on the limited warranty. Sequoia also comes with ToyotaCare, a plan covering normal factory-scheduled maintenance and 24-hour roadside assistance for two years or 25,000 miles, whichever comes first. Certain features include a trial period at no extra cost upon original date of new vehicle purchase or lease. After the trial period ends, a paid subscription is required. More detail on trial-periods and subscription-based features can be found at https://www.toyota.com/connected-services/. Toyota (NYSE:TM) has been a part of the cultural fabric in the U.S. for more than 60 years, and is committed to advancing sustainable, next-generation mobility through our Toyota and Lexus brands, plus our nearly 1,500 dealerships. Toyota directly employs more than 39,000 people in the U.S. who have contributed to the design, engineering, and assembly of nearly 32 million cars and trucks at our nine manufacturing plants. By 2025, Toyota's 10th plant in North Carolina will begin to manufacture automotive batteries for electrified vehicles. With the more electrified vehicles on the road than any other automaker, a quarter of the company's 2021 U.S. sales were electrified. To help inspire the next generation for a career in STEM-based fields, including mobility, Toyota launched its virtual education hub at www.TourToyota.com with an immersive experience and chance to virtually visit many of our U.S. manufacturing facilities. The hub also includes a series of free STEM-based lessons and curriculum through Toyota USA Foundation partners, virtual field trips and more. For more information about Toyota, visit www.ToyotaNewsroom.com. For customer inquiries, please call 800-331-4331. Media Contacts: Connor Hoffman [email protected] Note to Editors: Photography can be found on ToyotaNewsroom.com SOURCE Toyota	https://www.prnewswire.com/news-releases/live-legendary-with-the-all-new-2023-sequoia-full-size-suv-301563726.html	2022-06-08T12:04:22	en	0.914289
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Major machine translation market participants include AWS (Amazon.com, Inc.), Alibaba Cloud, AppTek LLC, Baidu, Google LLC (Alphabet Inc.), Cloudwords Inc., Microsoft Corporation, IBM Corporation, Moravia IT s.r.o. (RWS Holdings), Lionbridge Technologies, Inc., Omniscien Technologies, Raytheon BBN Technologies Corp. (Raytheon Technologies), Smart Communications, Inc., Systran International, and Tencent Cloud TMT SELBYVILLE, Del., June 8, 2022 /PRNewswire/ -- The machine translation market is expected to surpass USD 7.5 billion by 2030, as reported in a research study by Global Market Insights Inc. The growth can be attributed to the growing demand for translating text at a rapid rate and generating multi-lingual content. The increasing complexity of customer translation requirements will propel the hybrid machine translation segment growth. In this technology, multiple MT processes are used and combined into one machine translation system to obtain high-quality content. With an increasing focus on improving the customer experience, the deployment of single-translation systems is not always effective. It can impact the overall accuracy of the translated data. The technology is categorized into different methodologies including multi-engine translation, statistical rule generation, and multi-pass. These approaches are used to address the issues related to a single translation system and build a custom model for industry-specific solutions. Request for a sample of this research report @ https://www.gminsights.com/request-sample/detail/159 The BFSI sector will witness growth in the market owing to the introduction of new policies & subsiding loans for the agriculture industry. Government authorities are focusing on supporting farmers through these initiatives. For instance, in February 2022, the Indian government increased the agricultural credit target to around USD 232.2 billion for FY 2022-23 from USD 212.9 billion in FY 2021-2022. It will entice more farmers to set up bank accounts, from different rural locations in the country, for leveraging the monetary support. This factor will encourage the banking sector to incorporate its web pages or applications with advanced machine translation systems with multiple languages to allow the users to understand the information clearly. The growing automobile sector in Europe will fuel the machine translation market demand during the estimated timeframe. Global vehicle manufacturers are increasing their presence in the region to strengthen their positioning and expand their customer base. For instance, in March 2022, Tesla inaugurated a new Gigafactory in Berlin to cater to the demand for Electric Vehicles (EVs) in Europe. The factory is estimated to produce nearly 500,000 vehicles at the site annually, employing over 12,000 people. Companies in the sector use machine translation technology for corporate communication, training materials for operations, and technical document translation. MT helps them in streamlining communication and reducing the overall cost. Some major findings of the machine translation market report are: - The integration of AI in machine translation solutions will drive market growth. AI-based technology enables accurate, smooth, and automatic translation of one natural or written language into another target language. It estimates the quality of the machine-translated content. - A growing focus on content localization for better communication across businesses will boost the industry growth. Several companies from different sectors are investing in the technology for translating documents, manuals, and key information to prevent any financial & operational loss. - Increasing utilization of machine translation technology in the e-commerce sector will drive the industry expansion. Through these solutions, the market players are focusing on offering multi-lingual applications to the end-users, enabling a broad range of customers to understand the terminology in their preferred language. - Growing emphasis from technology providers on expanding their language and dialect lists will accelerate the market size. This factor will allow more customers to use these services for different applications. - Rising adoption of cloud services across SMEs and large organizations will spur machine translation technology deployment. Companies in different sectors utilize cloud technology due to its scalability, flexibility, and data security aspects. MT solutions can be easily integrated with the existing cloud infrastructure. Request for customization of this research report at https://www.gminsights.com/roc/159 Partial chapters of report table of contents (TOC): Chapter 2 Executive Summary 2.1 Machine translation industry 360º synopsis, 2018 – 2030 2.1.1 Business trends 2.1.2 Regional trends 2.1.3 Technology trends 2.1.4 Deployment model trends 2.1.5 Application trends Chapter 3 Machine Translation Industry Insights 3.1 Introduction 3.2 Impact of the coronavirus (COVID-19) pandemic 3.3 Ukraine-Russia war impact 3.4 Industry ecosystem analysis 3.5 Technology & innovation landscape 3.6 Regulatory landscape 3.7 Industry impact forces 3.8 Investment portfolio 3.9 Growth potential analysis 3.10 Porter's analysis 3.11 PESTEL analysis About Global Market Insights Global Market Insights Inc., headquartered in Delaware, U.S., is a global market research and consulting service provider; offering syndicated and custom research reports along with growth consulting services. Our business intelligence and industry research reports offer clients with penetrative insights and actionable market data specially designed and presented to aid strategic decision making. These exhaustive reports are designed via a proprietary research methodology and are available for key industries such as chemicals, advanced materials, technology, renewable energy and biotechnology. Contact Us: Arun Hegde Corporate Sales, USA Global Market Insights Inc. Phone: 1-302-846-7766 Toll Free: 1-888-689-0688 Email: [email protected] SOURCE Global Market Insights Inc.	https://www.prnewswire.com/news-releases/machine-translation-market-to-value-usd-7-5-billion-by-2030--says-global-market-insights-inc-301563769.html	2022-06-08T12:04:28	en	0.887532
San Francisco residents voted overwhelmingly to recall progressive District Attorney Chesa Boudin in a heated campaign that divided Democrats over crime, policing and public safety reform in the famously liberal city. Recall backers cheered the results as proof that San Franciscans wanted change in a chaotic DA's office. But Boudin remained defiant to supporters, saying the movement for justice would continue and blaming his loss on billionaire Republicans. Boudin was a first-time political candidate who narrowly won office in November 2019 as part of a national wave of progressive elections. The mayor will appoint his replacement, but Boudin could also run again in November. As of Wednesday morning, results showed the pro-recall vote leading 60-40 with 53% of precincts reporting.	https://www.wsfltv.com/news/national/san-francisco-ousts-liberal-da-chesa-boudin-in-heated-recall	2022-06-08T12:04:28	en	0.976261
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Malaria breakthrough: A collaboration between ISS, IRBM and CNR has led to the discovery of new molecules blocking the transmission of the parasite ROME, June 8, 2022 /PRNewswire/ -- The Istituto Superiore di Sanità, IRBM and CNR today announced collaborative research published in the journal Communications Biology (doi: 10.1038/s42003-022-03510-w) that identified new molecules which block the transmission of the malaria parasite from an infected person to the mosquito, the first step in developing new drugs to eliminate this major infectious disease. In response to the guidance of the World Health Organization to attack the malaria parasite on multiple fronts, researchers have collaborated, in recent years, in the search for new molecules able to block the transmission of the most dangerous of malarial parasites, Plasmodium falciparum - a project funded by the public-private consortium CNCCS, formed by CNR, ISS and IRBM. This work identified seven molecular structures (chemotypes), three of which have never been identified in the past, able to kill gametocytes and prevent the development of the parasite in the mosquito. The success of this work was possible thanks to the combination of biological knowledge on the parasite stages transmissible to the Anopheles mosquito (the gametocytes), innovative cell-based assays on transgenic parasites and the expertise in large-scale screening of pharmacologically active compounds. Giacomo Paonessa, Group Leader at IRBM, outlined that, "The biological assay funnel developed in this collaboration was able to efficiently and quickly screen 120,000 compounds, which corresponds to about a third of those tested so far by various laboratories all over the world in the search for new parasite anti-transmission drugs. This result therefore paves the way to wider screens to identify even better compounds against parasite transmission." "The action of the identified chemotypes is to interrupt the life cycle of P. falciparum and therefore the spread of malaria to other individuals," comments Pietro Alano, researcher at ISS, adding that, "The advantage of the new screening funnel is its efficiency and speed in identifying molecules active specifically against gametocytes as well as dual active molecules, that are able to kill the parasite stages causing the disease symptoms. Today, elimination of malaria requires both types of drugs." In the past five years the global fight against malaria has come to a halt, exacerbated today by the effects of the Covid-19 pandemic on the health systems of the most affected countries, mainly in Africa. In 2021, 240 million new cases and 630,000 deaths, especially African children under the age of 5, was the price imposed by this parasite on the health of humanity, a scenario made increasingly worrying by the emergence of parasites and mosquitoes resistant to the available frontline drugs and insecticides. Istituto Superiore di Sanità (ISS), is the main centre for research, control and technical-scientific advice on public health in Italy. It is supervised by the Ministry of Health. CNR - National Research Council, is a national research public institution with multidisciplinary proficiency, supervised by the Ministry of Education, University and Research (MUR). Founded in1923, it has the task of carrying out scientific research projects in the main fields of knowledge, applying their results for the development of the Country, in order to promote innovation, internationalization of the "research system" and fostering the competitiveness of the industrial system. The CNCCS - National Consortium is a private-public consortium between CNR – Consiglio Nazionale di Ricerca, ISS – Istituto Superiore di Sanità, and IRBM, with a mission to identify compounds acting on innovative biological targets. It also acts as a centre for translational research in rare, neglected and poverty-related diseases. Is a public-private central repository of organic compounds with an associated high throughput screening hub for the identification of novel lead compounds acting on biological targets of interest with the purpose of enabling and accelerating the translation of new basic research discoveries and scientific knowledge into the development of molecules to study gene function and biological mechanisms, and of novel medicines. IRBM is a drug hunting company working across all aspects of drug discovery and early development for different modalities – small molecule, peptides, and antibodies. IRBM fosters collaborations with organizations from the pharmaceutical, biotech and academic sectors to accelerate drug discovery from target validation and hit identification to candidate nomination. IRBM's scientists have discovered several drugs that are on the market, and more than 25 compounds have gone into clinical testing. For further information, visit www.irbm.com SOURCE IRBM	https://www.prnewswire.com/news-releases/malaria-breakthrough-a-collaboration-between-iss-irbm-and-cnr-has-led-to-the-discovery-of-new-molecules-blocking-the-transmission-of-the-parasite-301563899.html	2022-06-08T12:04:34	en	0.930729
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NEW YORK, June 8, 2022 /PRNewswire/ -- According to the market research report published by P&S Intelligence, in 2021, the global medical radiation detection, monitoring, & safety market was worth around $2,140.8 million, which is predicted to touch $4,373.8 million by 2030, advancing at an 8.3% CAGR from 2021 to 2030. The major factors driving the market include the snowballing cases of cancer, rising geriatric population, surging count of nuclear and radio diagnostic and therapeutic procedures, and growing number of diagnostic imaging centers. Market in North America Has Massive Growth Potential The industry in North America has had the biggest market share in recent years, and it is expected to grow at an 8.6% CAGR from 2021 to 2030. The region dominates the market owing to the increasing awareness of the health problems caused by overexposure to radiation and growing incidence of cancer. Similarly, the medical radiation detection, monitoring, & safety market is being propelled by the increasing radiation safety awareness and rising number of radio diagnostic procedures. Get the sample pages of this report at: https://www.psmarketresearch.com/market-analysis/medical-radiation-detection-monitoring-safety-market/report-sample Hospitals Category Leads Market The hospitals category accounted for a roughly 70% share of the medical radiation detection, monitoring, & safety market in 2021. This was due to the ever-increasing demand for medical radiation therapy and diagnosis, both conventional and nuclear. Radiation-based procedures can be performed in hospitals with ease due to the availability of the necessary equipment and experienced professionals. Furthermore, the count of outpatients and inpatients in hospitals is steadily increasing, and this trend will accelerate in the future. Market for Detectors Is Expected To Expand Rapidly The detectors category generated the highest revenue in the medical radiation detection, monitoring, & safety market, of $427.0 million, in 2021. The demand for medical radiation detection is growing as the number of radiography operations increases and medical staff becomes more aware of the necessity of radiation safety. Cancer patients often need radiation therapy, which requires the use of detectors to ascertain the dosage being given. Full-Body Protection Category Held Significant Share of Market In 2021, the full-body protection category accounted for over half the medical radiation detection, monitoring, & safety market share. The growing number of radiological operations and rising awareness of the hazards of radiation overexposure among radiologists, physicians, and patients can be credited for this category's large share. Likewise, the apron market is being pushed by a growth in the number of skilled radiology technicians, increase in safety awareness, and surge in the usage of radiation treatment as a result of the increase in cancer incidence. Browse detailed report on Global Medical Radiation Detection, Monitoring, & Safety Market Size, Share, and Demand Forecast Report, 2030 Radiation Therapy and Nuclear Medicine Used for Better Diagnosis and Treatment As a consequence of the advancements in radio pharmacy, information technology, and instrumentation, nuclear medicine has evolved significantly in the last decade. The increasing application of nuclear medicine in the diagnosis and treatment of diseases, including cancer and cardiovascular diseases, has raised the demand for solutions to detect and monitor monitoring medical radiation and protect patients and doctors from an overdose. Medical Radiation Detection, Monitoring, & Safety Market Segmentation Analysis By Product Type - Radiation Detection & Monitoring Products - Personal dosimeters - Active dosimeters - Passive dosimeters - Area process monitors - Environment radiation monitors - Surface contamination monitors - Radioactive material monitors - Detectors - Safety Products - Full-body protection - Barriers and shields - Aprons - Face Protection - Eye wear - Face masks - Hand Safety - Gloves - Attenuating sleeves By End User - Hospitals - Radiation therapy - Radiology - Dentistry - Nuclear medicine - Emergency care - Non-Hospitals - Imaging centers - Radiation therapy and cancer centers - Dental clinics - Orthopedic facilities Regional Outlook - North America - U.S. - Canada - Europe - U.K. - Germany - France - Spain - Italy - Asia-Pacific - China - Japan - India - Australia - South Korea - Latin America - Brazil - Mexico - Argentina - Middle East and Africa - Saudi Arabia - South Africa Browse Other Reports Published by P&S Global Radiation Dose Management Market Growth and Future Analysis Global Spinal X-Ray and CT Market Growth and Future Analysis Global Dental X-Ray Market Growth and Future Analysis About P&S Intelligence P&S Intelligence provides market research and consulting services to a vast array of industries across the world. As an enterprising research and consulting company, P&S believes in providing thorough insights on the ever-changing market scenario, to empower companies to make informed decisions and base their business strategies with astuteness. P&S keeps the interest of its clients at heart, which is why the insights we provide are both honest and accurate. Our long list of satisfied clients includes entry-level firms as well as multi-million-dollar businesses and government agencies. Contact: Prajneesh Kumar P&S Intelligence Phone: +1-347-960-6455 Email: [email protected] Web: https://www.psmarketresearch.com Follow Us: LinkedIn Twitter SOURCE P&S Intelligence	https://www.prnewswire.com/news-releases/medical-radiation-detection-monitoring--safety-market-to-surpass-4-373-8-million-revenue-by-2030--says-ps-intelligence-301563764.html	2022-06-08T12:04:40	en	0.903766
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SAN FRANCISCO, June 8, 2022 /PRNewswire/ -- The global metalworking fluids market size is expected to reach USD 15.1 million by 2030, as per the new report by Grand View Research, Inc., registering a CAGR of 3.8% in the forecast period. The demand is attributed to arise in demand for automotive and industrial machinery. Individual end-use sectors, such as machinery, metal fabrication, and transportation equipment, are driving the expansion of the market. Key Insights & Findings from the report: - Mineral-based MWFs accounted for a revenue share of 48.1% in 2021 due to the increased consumption owing to their low cost. - Water cutting oils application is anticipated to grow at the fastest CAGR over the forecast period due to product usage in operations, such as drilling, milling grinding, and mainly in heat dissipation for the proper machining process. - The machinery segment dominated the market in 2021 due to the high demand for construction equipment and increased infrastructural development activities. - The automobile industry is anticipated to witness a significant CAGR over the forecast period due to the high demand for automobile machinery. - The growth of the construction and electrical & power equipment sectors in emerging economies is also expected to drive the product demand. - Synthetic and mineral-based products aid in better tool performance, which has led to their high demand. Read 108-page market research report, "Metalworking Fluids Market Size, Share & Trends Analysis Report By Product (Mineral, Synthetic), By End-use (Machinery, Transportation Equipment), By Industrial End-use, By Application, And Segment Forecasts, 2022 - 2030", published by Grand View Research. Metalworking Fluids Market Growth & Trends The market is expected to be driven by strong development in the machinery and transportation equipment end-use industries over the projected period. Manufacturing is one of the core industries in North America and Europe. Advances in the manufacturing methods for the production of sophisticated end-use products, coupled with the increase in the exports of construction machinery and power, agricultural, and automotive equipment, have fueled the market growth. The sector is expected to benefit from increased production of construction machines and related parts for industrial, residential, and commercial construction. The rise in public-private partnerships is expected to boost the demand for a variety of construction components that use MWFs during their production. Because of the expanding building activities in these nations, emerging economies are likely to be critical for product growth. The increasing demand for electricity and upgrading of the existing infrastructure for electricity generation, transmission, and distribution, is anticipated to fuel the market for electrical & power equipment and related components. These components are manufactured using ferrous and non-ferrous metal parts, which consume MWFs during manufacturing. Metalworking Fluids Market Segmentation Grand View Research has segmented the metalworking fluids market report on the basis of product, application, end-use, industrial end-use, and region: MWFs Product Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2030) - Mineral - Synthetic - Bio-based MWFs Application Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2030) - Neat Cutting Oils - Water Cutting Oils - Corrosion Preventive Oils - Others MWFs End-use Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2030) - Metal Fabrication - Transportation Equipment - Machinery - Others MWFs Industrial End-use Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2030) - Construction - Electrical & Power - Agriculture - Automobile - Aerospace - Rail - Marine - Telecommunication - Healthcare MWFs Regional Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2030) - North America - U.S. - Canada - Mexico - Europe - Germany - Russia - France - Spain - Italy - U.K. - Switzerland - Denmark - Norway - Belgium - Poland - Czech Republic - Turkey - Sweden - Finland - Asia Pacific - China - India - Japan - South Korea - Singapore - Malaysia - Thailand - Australia - New Zealand - Central & South America - Brazil - Middle East & Africa List of Key Players in Metalworking Fluids Market - Houghton International, Inc. - Blaser Swisslube AG - BP plc - Exxon Mobil Corp. - Total S.A. - FUCHS - Chevron Corp. - China Petroleum & Chemical Corp. - Kuwait Petroleum Corp. Check out more related studies published by Grand View Research: - Plastic Processing Machinery Market - The global plastic processing machinery market size is expected to reach USD 43.7 billion by 2025, according to a new report by Grand View Research, Inc. The shift in trend towards mechanized packaging for increased efficiency and output is expected to drive demand. - Clear Brine Fluids Market - The global clear brine fluids market size is expected to reach USD 1.03 billion by 2025, according to a new report by Grand View Research, Inc. It is projected to expand at a CAGR of 3.3% during the forecast period. Increasing number of drilling operations is creating the need for completion and workover chemicals, thereby driving the demand for clear brine fluids. - Fracking Chemicals And Fluids Market - The global fracking chemicals & fluids market size is expected to reach USD 57.59 billion by 2025, expanding at a CAGR of 10.3%, according to a new report by Grand View Research, Inc. Globally increasing demand of fuel and electricity has been a major factor driving the market growth. Browse through Grand View Research's Petrochemicals Industry Research Reports. About Grand View Research Grand View Research, U.S.-based market research and consulting company, provides syndicated as well as customized research reports and consulting services. Registered in California and headquartered in San Francisco, the company comprises over 425 analysts and consultants, adding more than 1200 market research reports to its vast database each year. These reports offer in-depth analysis on 46 industries across 25 major countries worldwide. With the help of an interactive market intelligence platform, Grand View Research Helps Fortune 500 companies and renowned academic institutes understand the global and regional business environment and gauge the opportunities that lie ahead. Contact: Sherry James Corporate Sales Specialist, USA Grand View Research, Inc. Phone: +1-415-349-0058 Toll Free: 1-888-202-9519 Email: [email protected] Web: https://www.grandviewresearch.com Grand View Compass \| Grand View Pipeline Follow Us: LinkedIn \| Twitter SOURCE Grand View Research, Inc.	https://www.prnewswire.com/news-releases/metalworking-fluids-market-size-to-hit-15-1-billion-by-2030-grand-view-research-inc-301563858.html	2022-06-08T12:04:52	en	0.904275
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Includes oral presentation on Prospera test's two-threshold algorithm, showing the combination of donor quantity and donor fraction outperforms donor fraction alone AUSTIN, Texas, June 8, 2022 /PRNewswire/ -- Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA (cfDNA) testing, today announced that it has presented data on the clinical utility of the company's Prospera™ and Renasight™ tests in 14 sessions at the American Transplant Congress (ATC) 2022 meeting. This expands on the thirteen peer-reviewed papers that have been published over the last twelve months, demonstrating the strong performance of both assays. Phil Halloran, M.D., Ph.D., director of the Alberta Transplant Applied Genomics Centre, presented new data on the latest findings of the global, multisite, prospective Trifecta study, "Combining fraction and estimated amount of dd-cfDNA to assess kidney transplant rejection using molecular diagnoses and histology." The study demonstrates that the new two-threshold algorithm for the Prospera test - including both dd-cfDNA fraction and quantity - performed better than dd-cfDNA percentage alone in detecting active rejection, with an AUC of 0.88 when compared against molecular biopsy assessment and 0.82 when compared against histological biopsy assessment. This analysis in the Trifecta study features 367 fully-biopsy-matched samples from the 22 participating clinics in the U.S. and Europe. "The data presented at ATC, combined with other important studies, highlight Natera's dedication to innovation and continued leadership in testing for transplant rejection and genetic risks for kidney disease," said Sangeeta Bhorade, M.D., chief medical officer for organ health at Natera. "The evidence continues to support the use of Natera technology for aiding clinicians in making major care decisions for transplant patients." Data from the Trifecta study was also presented in three other ATC sessions, and a full listing of Natera's scientific sessions and presence can be found at https://www.natera.com/events/prospera-conference/ About the Prospera test The ProsperaTM test leverages Natera's core single-nucleotide (SNP)-based massively multiplexed PCR (mmPCR) technology to identify allograft rejection non-invasively and with high precision and accuracy, without the need for prior donor or recipient genotyping. The test works by measuring the fraction of donor-derived cell-free DNA (dd-cfDNA) in the recipient's blood. It may be used by physicians considering the diagnosis of active rejection, helping to rule in or out this condition when evaluating the need for diagnostic testing or the results of an invasive biopsy. The Prospera test has been clinically and analytically validated for performance regardless of donor relatedness, rejection type, and clinical presentation. It has been developed and its performance characteristics determined by Natera, the CLIA-certified laboratory performing the test. The test has not been cleared or approved by the US Food and Drug Administration (FDA). CAP accredited, ISO 13485 certified, and CLIA certified. About the Renasight test The RenasightTM test is a germline genetic test that screens for hereditary causes of kidney disease. It is indicated for patients with diagnosed kidney disease and is run from a patient's blood or saliva sample. Providers can use the Renasight test to identify a genetic predisposition, clarify a clinical diagnosis, or identify the etiology of an unknown kidney disease to help inform medical management. Additionally, genetic counseling and familial testing can be offered based on the test result. The test has been developed and its performance characteristics determined by the CLIA-certified laboratory performing the test. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). CAP accredited, ISO 13485 certified, and CLIA certified. About Natera NateraTM is a global leader in cell-free DNA testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that help lead to longer, healthier lives. Natera's tests are validated by more than 100 peer-reviewed publications that demonstrate high accuracy. Natera operates ISO 13485-certified and CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in Austin, Texas and San Carlos, California. For more information, visit www.natera.com. Forward-Looking Statements All statements other than statements of historical facts contained in this press release are forward-looking statements and are not a representation that Natera's plans, estimates, or expectations will be achieved. These forward-looking statements represent Natera's expectations as of the date of this press release, and Natera disclaims any obligation to update the forward-looking statements. These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual results to differ materially, including with respect to whether the results of clinical or other studies will support the use of our product offerings, our expectations of the reliability, accuracy and performance of our screening tests, or of the benefits of our screening tests and product offerings to patients, providers and payers. Additional risks and uncertainties are discussed in greater detail in "Risk Factors" in Natera's recent filings on Forms 10-K and 10-Q and in other filings Natera makes with the SEC from time to time. These documents are available at www.natera.com/investors and www.sec.gov. Contacts Investor Relations: Mike Brophy, CFO, Natera, Inc., 510-826-2350 Media: Kate Stabrawa, Communications, Natera, Inc., 720-318-4080 [email protected] SOURCE Natera, Inc.	https://www.prnewswire.com/news-releases/natera-showcases-leadership-in-transplantation-at-atc-2022-with-new-data-on-its-prospera-and-renasight-tests-301563616.html	2022-06-08T12:04:58	en	0.914994
Planned divestiture of Canadian cannabis business to cut costs and realign focus on increasing value of consumer products business LAVAL, QC, June 8, 2022 /PRNewswire/ - Neptune Wellness Solutions Inc. ("Neptune" or the "Company") (NASDAQ: NEPT) (TSX: NEPT), a diversified and fully integrated health and wellness company focused on plant-based, sustainable and purpose-driven lifestyle brands, today announced the launch of a new Consumer Packaged Goods (CPG) focused strategic plan to reduce costs, improve the Company's path to profitability and enhance current shareholder value. This plan builds on the Company's initial strategic review that took place in fall of 2021 and focuses on two primary actions: (1) planned accelerated divestiture of the Canadian cannabis business and (2) a realignment of focus and operational resources toward increasing the value of Neptune's consumer products business, which the Company believes is showing greater potential. These actions are also intended to preserve resources towards meeting its funding requirements in the near-term while driving long-term profitability and growth. The intended divestiture of the cannabis business would include the sale of the Mood Ring™ and PanHash™ brands, along with the Company's Sherbrooke, Quebec facility, in one or more transactions. The value of the facility was recently appraised at $21 million CAD by a third-party appraisal company. Neptune has retained Stifel GMP to support the divestiture efforts, with a focus on maximizing the value to Neptune shareholders. In order to accelerate its cost savings, the Company will focus on winding up its cannabis operations pending a transaction. This planned action is intended to provide significant cost savings and help maximize operational efficiencies, resulting in a 50% reduction in workforce, over 30% reduction of total payroll costs and an estimated annual cost savings of $5.8 million CAD. In addition, the Company expects to see additional cost savings from corresponding reductions in corporate overhead costs and professional fees. Finally, the exit of the Canadian cannabis business may impact the amount and structure of financing the company is currently seeking. It is expected to reduce the amount of financing the Company seeks, given a lower anticipated expense structure, along with anticipated cash inflows from the planned divestiture. Additionally, the divestiture is expected to facilitate working with a broader set of financing sources – including traditional banks and financial institutions that have policies restricting dealing with businesses exposed to regulated cannabis operations. "This is the final stage of our transition to a pure play, purpose driven consumer packaged goods Company. This strategic divestiture greatly simplifies our overall structure, enabling us to hyper-focus on those areas of the business we believe are best positioned for profitability and growth," said Michael Cammarata, President and CEO of Neptune. "Of course, the most difficult part of the Company and Board making this decision is the impact on our workforce. We are committed to working with those employees to ensure they are supported throughout this transition. I extend my deepest gratitude to each and every person impacted by this decision and thank them for their hard work and dedication to Neptune throughout their tenure." "Today's decision, while difficult, is a step that is necessary to best position Neptune for long term success," said Julie Phillips, Neptune's Chair of the Board. "Together with management, the Board has worked carefully to explore all possible avenues and we are confident that the decision to exit the Canadian cannabis sector and realign focus on our consumer goods brands is the best next move for both the Company and its shareholders." With the planned divestiture of its cannabis business, Neptune is renewing its focus on the core brands – Sprout Organics and Biodroga Solutions – that align closely with future consumer trends and show a greater potential for future growth and profitability. Sprout Organics, the fast-growing organic baby and toddler food brand, has made major distribution gains over the past year, expanding into Walmart and Target. The recent launch of licensed, co-branded product with CoComelon – the number one kids entertainment show globally – has far surpassed initial sales goals in Walmart stores. Neptune sees significant opportunity to continue to improve Sprout's margins and accelerate its path to profitability. Biodroga Solutions, Neptune's B2B nutraceuticals business, has a strong foundation and a robust pipeline for continued growth. The Company's supply chain capabilities and product development expertise can also be applied to future Neptune brand and product innovations. Cedrick Billequey, Biodroga's business leader, also oversees Forest Remedies, a vegan Omega supplement brand, providing synergies between the B2B business and consumer brands. The success of these businesses and their anticipated growth form the foundation for the future of Neptune as a CPG business built to serve the next generation of consumers. As part of the Company's renewed focus on its CPG brands and Sprout Organics in particular, Neptune is delighted to announce that Sarah Tynan, current Sprout Chief Customer Officer, is promoted to CEO of Sprout, effective immediately. Ms. Tynan has been instrumental in garnering big distribution gains for Sprout, including Walmart and Target, and leading the highly successful CoComelon partnership. She brings deep sales experience and business acumen, including previous roles at Newell Brands and Unilever, and will continue to drive the Sprout business forward. "Our goal with this strategic plan is to strengthen our cash position and enhance financial flexibility, centering focus on our higher potential CPG businesses," said Cammarata. "With Sarah Tynan as the new CEO of Sprout and Cedrick Billequey leading Biodroga Solutions and the personal care & beauty segments of our business, I'm confident we have not only the right plan, but the right team in place to take Neptune into its next stage of growth and profitability." Neptune Wellness will provide further detail on the execution of this new plan over the coming months. Headquartered in Laval, Quebec, Neptune is a diversified health and wellness company with a mission to redefine health and wellness. Neptune is focused on building a portfolio of high quality, affordable consumer products in response to long-term secular trends and market demand for natural, plant-based, sustainable and purpose-driven lifestyle brands. The Company utilizes a highly flexible, cost-efficient manufacturing and supply chain infrastructure that can be scaled to quickly adapt to consumer demand and bring new products to market through its mass retail partners and e-commerce channels. For additional information, please visit: https://neptunewellness.com/. Statements in this news release that are not statements of historical or current fact constitute "forward-looking statements" within the meaning of applicable securities laws. Such forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause the actual results, performance and achievements of Neptune to be materially different from historical results or from any future results, performance and achievements expressed or implied by such forward-looking statements. In addition to statements which explicitly describe such risks and uncertainties, readers are urged to consider statements labeled with the terms "believes", "belief", "cost savings", "estimates", "expects", "intends", "projects", "anticipates", "will", "should" or "plans" to be uncertain and forward-looking. Forward-looking statements relate to future events or future performance and reflect management's expectations or beliefs regarding future events including, but not limited to, statements with respect to the review of strategic and financial alternatives, the anticipated cost savings and operational efficiencies related to the Company's divestiture of its Canadian cannabis business, management's assessment of the potential for growth and profitability of its Sprout Organics and Biodroga Solutions brands, restructuring initiatives and anticipated costs, the expected objectives and financial targets underlying Neptune's CPG-Focused Strategic Plan as well as the anticipated benefits of such transactions and their expected impact on the Company's outlook, operations, opportunities, financial condition, business plan and overall strategy. Forward-looking statements are presented for the purpose of assisting investors and others in understanding certain key elements of the Company's current objectives, strategic priorities, expectations and plans, and in obtaining a better understanding of the Company's business and anticipated operating environment. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this news release. The forward-looking statements contained in this news release are expressly qualified in their entirety by this cautionary statement and the "Cautionary Note Regarding Forward-Looking Information" and "Risk Factors" sections contained in Neptune's latest Annual Information Form, which also forms part of Neptune's latest annual report on Form 40-F, and which is available on SEDAR at www.sedar.com, on EDGAR at www.sec.gov/edgar.shtml. With respect to the pursuit of an accelerated divestiture of the Canadian cannabis business and a realignment of focus and operational resources toward increasing the value of the Company's consumer products business discussed herein specifically, certain factors that could cause actual results to differ materially from those anticipated in the forward looking statements include, but are not limited to: the failure to satisfy the conditions to the completion of these transactions or delay in completing, and uncertainty regarding the length of time required to complete, such transactions, and all or part of the intended benefits therefrom not being realized and the anticipated proceeds therefrom not being available to the Company within the anticipated timeframe, or at all; and alternate sources of funding that would be used to replace the anticipated proceeds from such transactions may not be available when needed, or on desirable terms. Neptune does not undertake to update any such forward-looking statements whether as a result of new information, future events or otherwise, except as required by law. Neither NASDAQ nor the Toronto Stock Exchange accepts responsibility for the adequacy or accuracy of this release. SOURCE Neptune Wellness Solutions Inc.	https://www.prnewswire.com/news-releases/neptune-wellness-launches-new-cpg-focused-strategic-plan-to-improve-path-to-profitability-301563584.html	2022-06-08T12:05:04	en	0.948697
LAVAL, QC, June 8, 2022 /PRNewswire/ - Neptune Wellness Solutions Inc. ("Neptune" or the "Company") (NASDAQ: NEPT) (TSX: NEPT), a diversified and fully integrated health and wellness company focused on plant-based, sustainable and purpose-driven lifestyle brands, announced today that it has received conditional approval of the Toronto Stock Exchange ("TSX") with respect to the Company's proposed consolidation of its common shares (the "Common Shares") on the basis of one (1) post-consolidation Common Share for every thirty-five (35) pre-consolidation Common Shares (the "Consolidation"). The Consolidation was previously approved by the board of directors of the Company on June 3, 2022. Each fractional Common Share remaining after completion of the Consolidation that is less than one (1) whole of a Common Share will be increased to one (1) whole Common Share. The Consolidation will reduce the number of Common Shares issued and outstanding from approximately 198 million Common Shares to approximately 5.7 million Common Shares. The Consolidation is subject to the final approval of the TSX, along with other customary conditions relating to the Consolidation. The precise effective date of the Consolidation and the date upon which the Common Shares will begin trading on the NASDAQ and the TSX on a post-Consolidation basis will be announced at a later date. The Company's transfer agent, Computershare Investor Services Inc. ("Computershare"), will act as the exchange agent for the Consolidation. In connection with the Consolidation, Computershare will send to registered holders of Common Shares (the "Registered Holders") a letter of transmittal (the "Letter of Transmittal") that may be used by such Registered Holders to exchange their pre-Consolidation Common Share certificates for certificates in the capital of the Company representing the consolidated number of Common Shares. Until surrendered, each certificate representing pre-Consolidation Common Shares will represent the number of whole post-Consolidation Common Shares to which the holder is entitled as a result of the Consolidation. The post-Consolidated Common Shares issued will be done via a push-out to shareholders holding book shares / DRS Advice positions and pre-Consolidated Common Shares will become null and void. Shareholders holding Common Shares by way of a physical share certificate are required to deposit a completed Letter of Transmittal and the physical share certificates for cancellation to receive the applicable post-Consolidated Common Shares. Non-registered or beneficial holders holding their Common Shares through a bank, broker or other nominee will not need to complete a Letter of Transmittal and should note that such banks, brokers or other nominees may have specific procedures for processing the Consolidation. Shareholders holding their Common Shares with such a bank, broker or nominee and who have any questions in this regard are encouraged to contact their nominee. A copy of the Letter of Transmittal will be posted on the Company's issuer profile on SEDAR at www.sedar.com. The Company's name and trading symbol will remain unchanged on the Nasdaq and the TSX as a consequence of the Consolidation. Forward-Looking Statements Statements in this news release that are not statements of historical or current fact constitute "forward-looking statements" within the meaning of applicable securities laws. Such forward-looking statements involve known and unknown risks, uncertainties, and other unknown factors that could cause the actual results of Neptune to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. In addition to statements which explicitly describe such risks and uncertainties, readers are urged to consider statements labeled with the terms "believes", "belief", "expects", "intends", "projects", "anticipates", "will", "should" or "plans" to be uncertain and forward-looking. Forward-looking statements relate to future events or future performance and reflect management's expectations or beliefs regarding future events including, but not limited to, statements with respect to the completion of the Consolidation, including the timing thereof. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this news release. The forward-looking statements contained in this news release are expressly qualified in their entirety by this cautionary statement and the "Cautionary Note Regarding Forward-Looking Information" section contained in Neptune's latest Annual Information Form, which also forms part of Neptune's latest annual report on Form 40-F, and which is available on SEDAR at www.sedar.com, on EDGAR at www.sec.gov/edgar.shtml. All forward-looking statements in this news release are made as of the date of this news release. Neptune does not undertake to update any such forward-looking statements whether as a result of new information, future events or otherwise, except as required by law. Neither NASDAQ nor the Toronto Stock Exchange accepts responsibility for the adequacy or accuracy of this release. About Neptune Wellness Solutions Inc. Headquartered in Laval, Quebec, Neptune is a diversified health and wellness company with a mission to redefine health and wellness. Neptune is focused on building a portfolio of high quality, affordable consumer products in response to long-term secular trends and market demand for natural, plant-based, sustainable and purpose-driven lifestyle brands. The Company utilizes a highly flexible, cost-efficient manufacturing and supply chain infrastructure that can be scaled to quickly adapt to consumer demand and bring new products to market through its mass retail partners and e-commerce channels. For additional information, please visit: https://neptunewellness.com/. SOURCE Neptune Wellness Solutions Inc.	https://www.prnewswire.com/news-releases/neptune-wellness-solutions-inc-announces-share-consolidation-301563576.html	2022-06-08T12:05:10	en	0.936961
REHOVOT, Israel, June 8, 2022 /PRNewswire/ -- Nova (NASDAQ: NVMI), a leading innovator and a key provider of metrology solutions for advanced process control used in semiconductor manufacturing, today announced that Eitan Oppenhaim, President & Chief Executive Officer, and Dror David, Chief Financial Officer, will attend SEMICON West and hold investor meetings on July 12 and 13 at the Zelos Hotel, 12 4th Street, San Francisco, CA. SEMICON West will be held as a hybrid event from July 11-14, 2022, both live at San Francisco's Moscone Center as well as in a virtual format. Concurrently, Nova's management will hold meetings in a nearby location in San Francisco. To schedule a meeting and get all the pertinent details, please contact Miri Segal of MS-IR at [email protected]. SEMICON West is the world marketplace for microelectronics innovation, featuring nearly 1,500 international exhibitors from 54 different countries showcasing products and services across the manufacturing ecosystem – from design to fabrication. The global industry looks to SEMICON West for the most up-to-date information on the tools, technologies, and trends driving the design, manufacture, and business of microelectronics. About Nova Nova is a leading innovator and key provider of material, optical, and chemical metrology solutions for advanced process control in semiconductor manufacturing. Nova delivers continuous innovation by providing state-of-the-art high-performance metrology solutions for effective process control throughout the semiconductor fabrication lifecycle. Nova's product portfolio, which combines high-precision hardware and cutting-edge software, provides its customers with deep insight into developing and producing the most advanced semiconductor devices. Nova's unique capability to deliver innovative solutions enables its customers to improve performance, enhance product yields, and accelerate time to market. Nova acts as a partner to semiconductor manufacturers from its offices worldwide. Additional information can be found at Nova's website link - https://www.novami.com/. Nova is traded on Nasdaq & TASE, Nasdaq ticker: NVMI Forward-Looking Statements This press release contains forward-looking statements within the meaning of safe harbor provisions of the Private Securities Litigation Reform Act of 1995 relating to future events or our future performance, such as statements regarding, but not limited to, anticipated growth opportunities and projections about our business and its future revenues, expenses and profitability. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to differ materially from any future results, levels of activity, performance or achievements expressed or implied in those forward-looking statements. Factors that may affect our results, performance, circumstances or achievements include, but are not limited to, the following: catastrophic events such as the outbreak of COVID-19; increased information technology security threats and sophisticated computer crime; foreign political and economic risks; changes in U.S. trade policies; inability to protect our intellectual property; open source technology exposure; failure to compete effectively or to respond to the rapid technological changes; consolidation in our industry; difficulty in predicting the length and strength of any downturn or expansion period of the market we target; factors that adversely affect the pricing and demand for our product lines; dependency on a small number of large customers; dependency on a single manufacturing facility per product line; dependency on a limited number of suppliers; difficulty in integrating current or future acquisitions; lengthy sales cycle and customer delays in orders; political, economic, and military instability in Israel; risks related to our convertible notes; currency fluctuations; and quarterly fluctuations in our operating results. We cannot guarantee future results, levels of activity, performance or achievements. The matters discussed in this press release also involve risks and uncertainties summarized under the heading "Risk Factors" in Nova's Annual Report on Form 20-F for the year ended December 31, 2021 filed with the Securities and Exchange Commission on March 1, 2022. These factors are updated from time to time through the filing of reports and registration statements with the Securities and Exchange Commission. Nova Ltd. does not assume any obligation to update the forward-looking information contained in this press release. Company Contact: Dror David, Chief Financial Officer Tel: +972-73-229-5760 E-mail - [email protected] Nova website link - https://www.novami.com/ Investor Relations Contact: Miri Segal MS-IR LLC Tel: +917-607-8654 E-mail - [email protected] SOURCE Nova	https://www.prnewswire.com/news-releases/nova-to-attend-and-hold-investor-meetings-at-semicon-west-301563821.html	2022-06-08T12:05:16	en	0.909339
Ocean Visions and Running Tide announce the formation of independent Scientific Advisory Board PORTLAND, Maine, June 8, 2022 /PRNewswire/ -- Today, on World Oceans Day, Ocean Visions and Running Tide are proud to announce the formation of an independent Scientific Advisory Board convened and managed by Ocean Visions to guide the development of Running Tide's carbon removal system. Ocean Visions, a nonprofit organization, works to develop innovative and durable solutions to the complex challenges facing our ocean. Running Tide, a company headquartered in Portland, Maine, designs and builds technology that amplifies the natural power of the ocean to durably remove carbon, reverse ocean acidification, and restore ocean health. Ocean Visions will oversee the independent Scientific Advisory Board, and will recruit appropriate experts to advise on various aspects related to Running Tide's foundational science, quantification methods, and approach. Included in this expert group will be: - Dr. Jim Barry, Senior Scientist and Benthic Ecologist at the Monterey Bay Aquarium Research Institute and a leading expert in benthic marine environments. - Dr. Andreas Oschlies, Head of the Biogeochemical Modelling research unit at GEOMAR Helmholtz Centre for Ocean Research and a leading expert in oceanic carbon uptake. - Richard Donovan, a co-founder of the Forest Stewardship Council (FSC) and independent forest advisor with 45+ years' experience in community forest enterprises, rural development, forest certification, community forestry, watershed management, and biomass energy. - David Bannon, Board Member and Founder of Headwall Photonics, a leading designer and manufacturer of imaging sensors and spectral instrumentation and an expert in the deployment of advanced instrumentation for remote sensing and machine vision. Justin Ries, Senior Scientific Advisor at Running Tide, stated the following about the formation of the Board: "The Scientific Advisory Board convened by Ocean Visions comprises some of the world's experts in the fields of global carbon cycling, oceanography, marine ecology, forestry, carbon sequestration, environmental economics and policy, and systems engineering. These experts will provide critical guidance, perspective, and insight into all aspects of Running Tide's environmental and climate services. This engagement is exemplary of the collaboration between industry, policy, science, and engineering that is needed to tackle the CO2 problem at the requisite Earth system scale." The experts comprising this Board are selected based on their understanding of the key systems underlying and impacted by Running Tide's foundational science and carbon removals accounting approach. The guidance and recommendations produced by this Board will be considered in all aspects of Running Tide's methodologies and operations, including quantifying the removal of carbon, conducting environmental impact assessments (EIAs), and responsibly scaling Running Tide's processes globally. Additional experts across a diverse range of fields will also join the Board in the near future. According to Board Member Jim Barry, "Stabilizing the climate system through reduced emissions and carbon removal is likely to be the most important challenge facing society this century and beyond. Developing realistic carbon removal solutions and implementing them at climate-relevant scales will depend upon partnerships involving a wide range of stakeholders including engineering, science, industry and social sciences. As one of the Scientific Advisors for Running Tide's efforts to develop a kelp-sinking approach for ocean carbon sequestration, I'll provide expert advice in marine biology and ecology, and will help identify resources for scientific information relevant for any issues related to their carbon removal efforts." Marty Odlin, the founder and CEO of Running Tide, said of the announcement, "We are immensely pleased that Ocean Visions will be convening this distinguished Scientific Board. This is a critical opportunity to leverage our collective expertise toward solving the climate crisis, restoring ocean health, and delivering positive co-benefits to ecosystems and human communities, while setting a standard for responsible innovation within the carbon removal space." Ocean Visions was born of recognition that the diverse sectors and disciplines needed to design and advance effective solutions to ocean health are often siloed and disconnected. In 2019, a group of leading ocean research and academic institutions came together to bridge these silos and develop innovative and durable solutions to the complex challenges facing our oceans. Ocean Visions connects not only oceanographic and academic research institutions, but marine resource managers, conservation organizations, investors, entrepreneurs, and governments to collaborate on the development, testing, and deployment of scalable and equitable solutions. Together, they are committed to reducing (and ultimately reversing) greenhouse gas-driven changes to the ocean, building climate resiliency in coastal systems and communities, and enhancing ocean-based food security in the face of climatic change. Founded by Marty Odlin, an engineer and 4th generation commercial fisherman, and proudly headquartered in Portland, Maine, Running Tide designs and builds technology that amplifies the natural power of the ocean to durably remove carbon, reverse ocean acidification, and restore coastal ecosystems. Running Tide partners with leading carbon removal purchasers such as Stripe and Shopify, as well as the leaders in climate and ocean science including The Centre for Climate Repair at Cambridge, Ocean Visions, and the Roux Institute at Northeastern University. SOURCE Running Tide	https://www.prnewswire.com/news-releases/ocean-visions-and-running-tide-announce-the-formation-of-independent-scientific-advisory-board-301563488.html	2022-06-08T12:05:22	en	0.928852
OUTBACK STEAKHOUSE® ADDS COLLEGE BASEBALL AND SOFTBALL ATHLETES TO THE TeamMATES PROGRAM ROSTER Outback and its TeamMATES will launch limited-edition NFTs on National Onion Day that will unlock rewards from the brand TAMPA, Fla., June 8, 2022 /PRNewswire/ -- Outback Steakhouse® is rounding out the college year and rounding the bases with eight new college baseball and softball athletes, signing* them to NIL deals as part of the Outback TeamMATES** program. Embracing Outback's connection with college athletes and sports fans across the country, the TeamMATES program will take this connection one step further through the launch of an NFT collection that will engage and reward consumers in an entirely new way. To celebrate the addition of the new TeamMATES, Outback will release a limited-edition series of 8,000 NFTs, which will be available to Outback fans free of charge, set to launch on National Onion Day, in honor of the famed Bloomin' Onion. The NFTs will be redeemable across all Outback Steakhouses for rewards from the brand. The Outback TeamMATES class of 2022 for college baseball and softball includes: - University of Oklahoma Softball – Jocelyn Alo (2x USA Softball National Player of the Year – 2021 and 2022) & Jayda Coleman (2021 All-American 1st Team) - University of Washington Softball – Baylee Klingler (2021 All-American 2nd Team) & Kelley Lynch (2021 Pac-12 Freshman Team) - University of Tennessee Baseball – Jordan Beck (2022 Golden Spikes Award Preseason Watch List) & Ben Joyce (Pitched NCAA record 105.5 mph) - University of Florida Baseball – Hunter Barco (No. 7 Midseason Collegiate 2022 MLB Draft Prospect – d1baseball.com) & Colby Halter (2022 Collegiate Baseball National Player of the Week – Feb. 28) From players bringing the heat with 105mph fastballs, to All-Americans and top projected draft picks, the baseball and softball TeamMATES have stepped up to the plate and delivered this season. Off the field, each TeamMATE will be promoting a lineup of these limited-edition NFTs. The TeamMATES will highlight the NFT drop on their social media channels, alerting fans about the opportunity to own digital collectables that unlock access to exclusive prizes offered by Outback. Fans can be the first to receive news about the NFT drop by visiting http://outbacknft.xyz, with the exact prizes being revealed on National Onion Day on June 27th. "As we continue to grow the TeamMATES program, we're seeking new opportunities to engage with athletes and fans in a unique way," said Brett Patterson, President of Outback Steakhouse®. "In the latest iteration of the program, we're celebrating America's pastime and integrating NFTs as a way to rally fans of baseball, softball and Outback." Giving back is one of Outback Steakhouse's® core values and will continue to be a focal point during the spring sports season, as the brand will help the TeamMATES support charities that they are passionate about. Outback Steakhouse® will continue to build the TeamMATES program with additional male and female college athletes throughout the year, with all eligible student-athletes for the 2022/2023 school year encouraged to apply for consideration at www.outback.com/teammates. The deadline for the fall application period is August 12, 2022. To date, Outback has fielded more than 350 applications and has accepted 150 athletes across 24 different NCAA Division I sports into the program. Athletes accepted through the open call application will receive Outback Steakhouse® gift cards and official TeamMATES merchandise. To learn more about Outback Steakhouse®, its TeamMATES program, please visit www.outback.com/teammates. Download the new app at www.outback.com/app. For more information about Outback Steakhouse®, please visit www.outback.com or follow Outback on Facebook, Twitter, Instagram or TikTok. Athletes were signed in accordance with recent NIL policy. * The Brand Marketing division of Excel Sports Management was tapped by Outback to develop the brand's NIL endorsement program, advising on strategy and leading talent procurement and campaign execution. There's a special spirit at Outback Steakhouse®. One where mates gather, stories are exchanged, and steakhouse favorites flow as freely as the conversation. Serve it up with a dash of Aussie hospitality, and you've got all the makings of a great experience you'll want to share with your friends, time and time again. We're known for high quality, juicy steaks with your choice of big cuts and bold flavor, cooked just the way you like it. Spirited drinks that start the night off right and a heap of craveable dishes and fan favorites like our iconic Bloomin' Onion. For more information, please visit outback.com or the Outback Facebook page. Erin Murphy, PRESS PR + Marketing 207-809-9662 / [email protected] Zach Hrubic, Excel Sports Management 908-477-5230 / [email protected] SOURCE Outback Steakhouse	https://www.prnewswire.com/news-releases/outback-steakhouse-adds-college-baseball-and-softball-athletes-to-the-teammates-program-roster-301563521.html	2022-06-08T12:05:34	en	0.908657
Bouncy, customizable Brown Sugar Jelly unveiled nationwide as a permanent menu addition for cold beverages EMERYVILLE, Calif., June 8, 2022 /PRNewswire/ -- Today, Peet's Coffee introduces its Summer of Jelly menu celebrating the refreshing taste, vibrant colors and unique customization of boba-inspired coffee and tea beverages. As younger U.S. consumers drive demand for boba-inspired specialty drinks1, Peet's debuts a new line of plant-based coffee and tea customized beverages featuring Brown Sugar Jelly for refreshing flavor and texture. Sweet and bouncy Jelly are fully plant-based and can now be added to any cold beverage at Peet's as a permanent menu option. From the new Brown Sugar Cold Brew Oat Latte to a Citrus Green Tea Shaker with Brown Sugar Jelly, Peet's summer menu offers the customization and bright layers that fans of Jelly and boba crave, matched with Peet's aromatic, freshly roasted coffee and tea selections. "Jelly beverages are a refreshing treat that can be dreamed up and enjoyed with endless flavor and color combinations, especially during summer," said Patrick Main, Senior Beverage Innovator. "At Peet's, our Brown Sugar Jelly is fully plant-based and can be added to any cold drink for refreshing sweetness, irresistible texture and luscious layers that look and taste delicious." Peet's Summer of Jelly products include: - Brown Sugar Jelly – Permanent addition - Peet's Coffee introduces playful, plant-based Brown Sugar Jelly to add refreshing sweetness and texture to any iced coffee or tea. Crafted for customization, their bouncy texture can be added to any iced beverage for a bit of fun in every sip. - Brown Sugar Cold Brew Oat Latte – Permanent addition - The familiar sweetness of Brown Sugar with a layer of creamy oat milk and a float of Peet's signature bold, juicy Baridi Cold Brew. Served with new Brown Sugar Jelly and ice for a fun and dynamic experience. - Iced Brown Sugar Matcha Oat Latte – Permanent addition - Organic Ceremonial Matcha Green Tea is prized for its distinctive flavor and creamy texture. Here, it's iced and layered over new bouncy Brown Sugar Jelly, Brown Sugar syrup, and luscious oat milk. - Citrus Green Tea Shaker with Brown Sugar Jelly – Summer feature - When lush Mighty Leaf Green Tea Tropical is hand-shaken with floral Yuzu purée, lemonade, and real citrus slices, all over a scoop of new Brown Sugar Jelly, it's a whole new experiential take on refreshing island vibes. - Strawberry Lemon Tea Shaker with Brown Sugar Jelly – Summer feature - Brisk Mighty Leaf Summer Solstice black tea, hand-shaken with lemonade and tangy strawberry purée all over a scoop of Brown Sugar Jelly, for a sweet, summery, totally fun experience with each sip. - Brown Sugar Oat Latte (Hot or Iced) – Summer feature - The familiar flavor of Brown Sugar sweetens luscious oat milk and bold, smooth Espresso Forté® for a cup that's equally velvety whether enjoyed hot or iced. Peet's Coffee is offering an exclusive promotion for all new Peetnik Rewards Members2 who will receive $3 off a Jelly beverage when they download the Peet's App and enter promo code JELLY3 at registration from June 8-22, 2022. Download the Peet's app here. Also, this summer, coffee drinkers are invited to soak in the sunshine with Peet's Zenith Summer Blend. This sweet and easy-drinking medium roast coffee invokes lighthearted summer vibes whether brewed hot or cold. Guatemala's sweet chocolate-caramel notes are at the forefront, with New Guinea giving the blend some heft, balanced by Rwanda's juicy cherry cola notes. The blend is available in retail stores and online for a limited time. Peet's Coffee honors Pride Month with the return of Peet's Rainbow Sugar Cookie, available now through June 30. As part of the company's longtime community commitment, Peet's is providing a $20,000 donation to SF LGBT Center, a non-profit organization fostering resources, support, and a safe space for LGBTQ individuals in San Francisco. To learn more about Peet's Summer of Jelly menu and to find a Coffeebar location near you, visit www.peets.com. - Source Bloomberg. - $3 off a Jelly beverage when you download the Peet's app, 6/8 - 6/22/2022 Offer valid for $3 off your purchase of a Jelly Beverage, any size, at participating Peetnik Rewards locations. Offer valid for 7 days from issuance. Transaction must include one (1) bar-made beverage with Jelly. Offer valid for one-time use only. Must apply offer at checkout to redeem. Offer not valid on previous purchases. May not be combined with other Peetnik Rewards offers. Only transactions more than $0 will qualify for points. Taxes, surcharges, or fees may apply. No cash value, substitutions, or rainchecks. This offer is exclusive to you and your Peetnik Rewards account, and cannot be reproduced, transferred, or used by any else. Peet's reserves the right to withdraw or change the offer terms at any time, at its discretion, without notice. When Alfred Peet founded Peet's Coffee® in Berkeley, California in 1966, he introduced an artisan movement creating the U.S. specialty coffee industry. Considered the "Big Bang of coffee," Peet's legacy – sourcing the world's best beans, artisan roasting for rich, premium taste and crafting beverages by hand – lives on today in every cup, whether ordered online, selected at a grocery store then brewed at home or served in any one of over 270 Peet's Coffee locations in the U.S and China. Peet's Coffee is committed to the welfare of people and the planet, with 100 percent of its coffee purchases verified as responsibly sourced per Enveritas standards. The company operates the first LEED® Gold certified roastery in the United States. Visit www.peets.com and connect @peetscoffee. Images can be downloaded here SOURCE Peet's Coffee Inc.	https://www.prnewswire.com/news-releases/peets-coffee-introduces-summer-of-jelly-with-plant-based-boba-inspired-coffee-and-tea-menu-301563762.html	2022-06-08T12:05:40	en	0.898465
Moderna says updated COVID shot boosts omicron protection (AP) - Moderna’s experimental COVID-19 vaccine that combines its original shot with protection against the omicron variant appears to work, the company announced Wednesday. COVID-19 vaccine makers are studying updated boosters that might be offered in the fall to better protect people against future coronavirus surges. Moderna’s preliminary study results show people given the combination shot experienced an eight-fold increase in virus-fighting antibodies capable of targeting the omicron mutant, the company announced. Today’s COVID-19 vaccines all are based on the original version of the coronavirus. They’re still providing strong protection against severe disease, hospitalization and death even after the appearance of the super-contagious omicron variant -- especially if people have had a booster dose. But the virus continues to mutate rapidly in ways that let it evade some of the vaccines’ protections and cause milder infections. So U.S. regulators, and the World Health Organization, are considering whether to order a change in the vaccine recipe for a new round of booster shots in the fall -- when cold weather and kids returning to school are expected to drive yet another surge. Key questions: How to make that change without losing the continued strong protection against COVID-19′s worst outcomes? And what’s the right variant to target? After the huge winter omicron surge, that mutant’s genetically distinct siblings now are the main threats, including one that’s fueling the current U.S. wave of infections. The Food and Drug Administration has set a meeting in late June for its scientific advisers to debate those questions and evaluate data from vaccine makers’ tests of potential new formulas. Pfizer also is studying a combination shot, what scientists call a bivalent vaccine. Moderna said its new study found that a month after the combo shot, recipients harbored higher omicron-fighting antibody levels -- and cross-protection against other prior variants — than the original vaccine triggers. However, antibodies naturally wane so it’s not clear how long the protection against infection will last. The study was performed in 437 people, and safety was similar to today’s boosters, Moderna said. The results were announced in a press release and haven’t undergone scientific review. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Copyright 2022 The Associated Press. All rights reserved.	https://www.wlbt.com/2022/06/08/moderna-says-updated-covid-shot-boosts-omicron-protection/	2022-06-08T12:05:42	en	0.933442
SAN FRANCISCO, June 8, 2022 /PRNewswire/ -- The global peptide therapeutics market size is expected to reach USD 68.7 billion by 2030, according to a new report by Grand View Research, Inc. It is expected to expand at a CAGR of 6.4% from 2022 to 2030. Increasing demand for efficient and rapid-acting therapeutics for the treatment of cancer and other lifestyle-associated disorders, which result in lesser adverse effects, is anticipated to propel market growth. The rising incidence of cancer calls for exploring and introducing other means of therapies and low-cost treatment alternatives is expected to drive the market. Moreover, the growing geriatric population is expected to widen the consumer base by triggering the incidence rate of target diseases such as cancer and diabetes, which is expected to drive the demand for peptide therapeutics. Key Insights & Findings from the report: - By application, cancer held the second-largest revenue share in 2021 owing to the increasing demand for alternative therapeutics over conventional treatment options. Peptides are being used as potential therapeutic agents in cancer treatment. - The generic type segment is expected to showcase an upward shift due to the patent expiration of blockbuster peptides and supportive government initiatives pertaining to the introduction of the generic class. - By type of manufacturers, the outsourced segment is expected to expand at a lucrative CAGR of 6.6% over the forecast period owing to the requirements of complex procedures and a shift in preference toward outsourcing, which helps in eliminating the cost of production. - By synthesis technology, hybrid technology is expected to witness the fastest growth over the forecast period. Benefits associated with this technology such as time conservation and ease of usage for both solid- and liquid-phase peptide synthesis are the key factors affirming growth. - North America held the largest share in terms of revenue in 2021 owing to a higher level of awareness pertaining to genomics and proteomics products, well-established R&D infrastructure, and rising funding initiatives. - Asia Pacific is expected to register a lucrative growth rate of 8.7% over the forecast period. The presence of an established generic industry and API providers in this region, coupled with the growing economic stability in some of the countries, is expected to propel market growth. Get more Industry Insights from full market research report with TOC, "Peptide Therapeutics Market Size, Share & Trends Analysis Report By Application, By Type, By Type of Manufacturers, By Route of Administration, By Synthesis Technology, By Region, And Segment Forecasts, 2022 - 2030", published by Grand View Research. Peptide Therapeutics Market Growth & Trends As per the International Agency for Research on Cancer (GLOBOCAN 2020) report, there will be 19,292,789 new cancer cases diagnosed globally in 2020, with 9,958,133 cancer deaths. Furthermore, the five-year prevalence of cancer was projected to be 50,550,287 worldwide. The global number of new cases of cancer is projected to reach 28,887,940 by 2040. As a result, the higher incidence of cancers around the world is set to perform an important role in the development of peptide therapeutics over the forecast period. Besides that, increasing awareness among health care providers and patients about the negative effects of chemotherapy and/or radiation therapy is a primary factor influencing the increased emphasis on alternative therapeutics like peptide-based drugs. Technological advancements in the peptide manufacturing process are driving the market during the forecast period. Manufacturers and suppliers are focusing on the adoption of novel technologies to manufacture efficient drug molecules with low time and capital investment. Improvement in purification and automation process and less generation of waste are additional factors contributing to the market growth. For instance, in March 2022, Amgen announced the official opening of its latest bio-manufacturing facility in Holly Springs, North Carolina. The facility, which is set to open in 2025, will help cope with the growth of Amgen's medicines, which treat serious diseases like cancer and heart disease. The COVID-19 pandemic is anticipated to spur the spectrum of cancer care, which includes delayed diagnoses, therapeutic interventions, and the impeding of clinical trials focused on developing cost-effective therapeutics for cancer treatment, with peptide therapeutics for cancer treatment being no exception, as per a research article published in Nature Cancer, 2020. There have been 21 peptide drugs in therapies for the treatment of COVID-19 as of May 2020, such as 15 synthetic peptides for the therapies of acute respiratory distress syndrome (ARDS) as well as other respiratory illnesses induced by severe acute respiratory infection. However, current implementations of peptide therapeutics in oncological and metabolic disorders and other fields have been hampered by drug shortages, operational problems, and the slow progress of clinical trials involving non-COVID-19 therapeutics. For instance, in May 2022, EVER Pharma announced that Bortezomib has received EU-wide approval for the treatment of individuals with symptomatic myeloma and mantle cell lymphoma1. In May 2022, The European Commission approved Novartis' Jakavi post-steroid therapy for acute and chronic graft-versus-host ailments. Jakavi will be the first JAK1/2 inhibitor widely available for patients in Europe with steroid-refractory graft-versus-host ailment. In September 2021, Nimble Therapeutics and Incyte entered into strategic collaborative research to discover additional new peptide therapies. Peptide Therapeutics Market Segmentation Grand View Research has segmented the global peptide therapeutics market by application, type, type of manufacturers, route of administration, synthesis technology, and region: Peptide Therapeutics Market - Application Outlook (Revenue, USD Million, 2017 - 2030) - Cancer - Metabolic - Cardiovascular Disorder - Respiratory - GIT - Antiinfection - Pain - Dermatology - CNS - Renal - Others Peptide Therapeutics Market - Type Outlook (Revenue, USD Million, 2017 - 2030) - Generic - Innovative Peptide Therapeutics Market - Type of Manufacturers Outlook (Revenue, USD Million, 2017 - 2030) - In-house - Outsourced Peptide Therapeutics Market - Route of Administration Outlook (Revenue, USD Million, 2017 - 2030) - Parenteral Route - Oral Route - Pulmonary - Mucosal - Others Peptide Therapeutics Market - Synthesis Technology Outlook (Revenue, USD Million, 2017 - 2030) - Solid Phase Peptide Synthesis (SPPS) - Liquid Phase Peptide Synthesis (LPPS) - Hybrid Technology Peptide Therapeutics Market - Regional Outlook (Revenue, USD Million, 2017 - 2030) - North America - U.S. - Canada - Europe - Germany - U.K. - Asia Pacific - China - Japan - India - Latin America - Mexico - Brazil - MEA - South Africa List of Key Players in Peptide Therapeutics Market - Eli Lilly and Company - Pfizer, Inc. - Amgen, Inc. - Takeda Pharmaceutical Company Limited - Teva Pharmaceuticals Industries Ltd. - Lonza Inc. - Sanofi - Bristol-Myers Squibb (BMS) - AstraZeneca PLC - GlaxoSmithKline plc (GSK) - Novartis AG - Novo Nordisk A/S Check out more related studies published by Grand View Research: - Prostate Cancer Therapeutics Market - The global prostate cancer therapeutics market is expected to reach USD 12.0 billion by 2025, according to a new report by Grand View Research, Inc. According to the American Cancer Society, approximately 1 in 7 men will be diagnosed with prostate cancer in their lifetime. - Peptide Synthesis Market - The global peptide synthesis market size is expected to reach USD 1,011.99 million by 2026 growing at a CAGR of 13.0%, according to a new report by Grand View Research, Inc. Significant research and innovation targeted towards the development of peptide therapeutics is set to boost the market growth in the near future. - Pruritus Therapeutics Market - The global pruritus therapeutics market is expected to reach USD 16.38 Billion by 2025, according to a new study by Grand View Research, Inc. Growing worldwide prevalence of atopic dermatitis, allergic contact dermatitis, and urticaria is expected to drive market growth during the forecast period. Browse through Grand View Research's Pharmaceuticals Industry Research Reports. About Grand View Research Grand View Research, U.S.-based market research and consulting company, provides syndicated as well as customized research reports and consulting services. Registered in California and headquartered in San Francisco, the company comprises over 425 analysts and consultants, adding more than 1200 market research reports to its vast database each year. These reports offer in-depth analysis on 46 industries across 25 major countries worldwide. With the help of an interactive market intelligence platform, Grand View Research Helps Fortune 500 companies and renowned academic institutes understand the global and regional business environment and gauge the opportunities that lie ahead. Contact: Sherry James Corporate Sales Specialist, USA Grand View Research, Inc Phone: 1-415-349-0058 Toll Free: 1-888-202-9519 Email: [email protected] Web: https://www.grandviewresearch.com Grand View Compass \| Grand View Pipeline Follow Us: LinkedIn \| Twitter SOURCE Grand View Research, Inc.	https://www.prnewswire.com/news-releases/peptide-therapeutics-market-to-be-worth-68-7-billion-by-2030-grand-view-research-inc-301563801.html	2022-06-08T12:05:46	en	0.906275
MONTREAL, June 8, 2022 /PRNewswire/ - Alithya Group inc. (TSX: ALYA) (NASDAQ: ALYA) ("Alithya") will disclose financial results for its fourth quarter and fiscal 2022, ended March 31, 2022, on June 17, 2022. Alithya will host a conference call followed by a question and answer period for the financial community at 9:00 a.m. (Eastern time). Financial statements, MD&A, and presentation will be posted on the Investors page of Alithya's website (https://www.alithya.com/en/investors). For those unable to participate on the live call, a replay will be made available until July 17, 2022, by opening a session at https://www.icastpro.ca/muu7r8. Alithya is a North American leader in strategy and digital transformation, employing a dedicated and highly skilled workforce of 3,600 professionals in Canada, the United States, and internationally. Since its founding in 1992, Alithya's capacity, size, and capabilities have continuously evolved, guided by a long-term strategic vision to become the trusted advisor of its clients. The company's integrated offer is based on four pillars of expertise: business strategies, enterprise cloud solutions, application services, and data and analytics. Alithya deploys leading-edge solutions, services, and skills as one of the most prominent consulting firms, driving successful digital change as a trusted advisor to customers in a variety of sectors, including financial services, manufacturing, renewable energy, telecommunications, transport and logistics, professional services, healthcare, government, and beyond. View original content: SOURCE Alithya	https://www.wlbt.com/prnewswire/2022/06/08/alithya-release-fourth-quarter-fiscal-2022-financial-results-june-17/	2022-06-08T12:05:48	en	0.948415
Microsoft technology empowers scalability for consumer products leader CINCINNATI and REDMOND, Wash., June 8, 2022 /PRNewswire/ -- On Wednesday, The Procter & Gamble Company (NYSE: PG) (P&G) and Microsoft Corp. announced a new multiyear collaboration that will leverage the Microsoft Cloud to help create the future of digital manufacturing at P&G. The two companies will co-innovate to accelerate and expand P&G's digital manufacturing platform and leverage the Industrial Internet of Things (IIoT) to bring products to consumers faster, increase customer satisfaction and improve productivity to reduce costs. "Together with Microsoft, P&G intends to make manufacturing smarter by enabling scalable predictive quality, predictive maintenance, controlled release, touchless operations and manufacturing sustainability optimization — which has not been done at this scale in the manufacturing space to date," said P&G CIO Vittorio Cretella. "At P&G, data and technology are at the heart of our business strategy and are helping create superior consumer experiences. This first-of-its-kind co-innovation agreement will digitize and integrate data to increase quality, efficiency and sustainable use of resources to help deliver those superior experiences." With Microsoft Azure as the foundation, the new collaboration marks the first time that P&G can digitize and integrate data from more than 100 manufacturing sites around the world and enhance its AI, machine learning and edge computing services for real-time visibility. This will enable P&G employees to analyze production data and leverage artificial intelligence to immediately make decisions that drive improvement and exponential impact. Accessing this level of data, at scale, is rare within the consumer goods industry. P&G selected Microsoft as its preferred cloud provider to build the future of digital manufacturing based on a four-year history of successfully working together on data and AI. The new collaborative effort will: - Allow for better utilization of data, AI capabilities and digital twins technology. - Optimize manufacturing environmental sustainability efforts. - Increase workforce efficiency and productivity. "We are excited to help P&G accelerate its digital manufacturing platform using Microsoft Azure, AI and IIoT to accommodate volatility in the consumer products industry with innovative, agile solutions that can easily scale based on market conditions," said Judson Althoff, Microsoft's chief commercial officer. "Our partnership will further P&G's growth and business transformation through digital technology that seamlessly connects people, assets, workflow and business processes that promote resiliency." Empowering technicians and advancing operations with IIoT P&G is already innovating and using Azure IoT Hub and IoT Edge to help manufacturing technicians analyze insights with greater speed and efficiency, creating improvements in the production of its baby care and paper products with pilot projects happening in Egypt, India, Japan and the United States. Diapers and data: Quality control and process improvements P&G is making advancements in its diaper manufacturing process to reduce manufacturing downtime, minimize scrap and lower maintenance expenses by automatically detecting and resolving the largest causes of line stops and rework using machine learning. The production of diapers involves assembling many layers of material at high speed with great precision to ensure optimal absorbency, superior leak protection and outstanding comfort. The new IIoT platform uses machine telemetry and high-speed analytics to continuously monitor production lines to provide early detection and prevention of potential issues in the material flow. This improves cycle time, reduces rework losses and ensures quality, while simultaneously improving operator productivity. Pioneering paper towels In a pilot with Microsoft, P&G can now better predict finished paper towel sheet lengths, improving the ability to deliver the right amount of product to the consumer. With the new IIoT platform, P&G can collect data from sensors on the manufacturing line and use technologies like advanced algorithms, machine learning and predictive analytics so it can improve manufacturing efficiencies. Increasing sustainability and predicting equipment failure To optimize manufacturing sustainability, P&G will use Microsoft's machine learning and data storage platforms to improve energy utilization across its paper machines in Family Care. With the efficiency and speed of cloud computing, P&G teams can analyze large volumes of holistic data sets and pinpoint energy efficiency and machine maintenance opportunities across the manufacturing process. The Azure platform will allow P&G to easily integrate event summary data — such as production runs, downtime, changeovers and more — along with historical data. Co-innovation with a new Digital Enablement Office and incubator To accelerate technology integration and support pilot programs, Microsoft and P&G have co-created a Digital Enablement Office (DEO) staffed by experts from both organizations. They will jointly deploy the Azure platform, and the DEO also intends to serve as an incubator to create high-priority business scenarios in the areas of product manufacturing and packaging processes that can be implemented across P&G. About Procter & Gamble P&G serves consumers around the world with one of the strongest portfolios of trusted, quality, leadership brands, including Always®, Ambi Pur®, Ariel®, Bounty®, Charmin®, Crest®, Dawn®, Downy®, Fairy®, Febreze®, Gain®, Gillette®, Head & Shoulders®, Lenor®, Olay®, Oral-B®, Pampers®, Pantene®, SK-II®, Tide®, Vicks®, and Whisper®. The P&G community includes operations in approximately 70 countries worldwide. Please visit http://www.pg.com for the latest news and information about P&G and its brands. For other P&G news, visit us at www.pg.com/new. About Microsoft Microsoft (Nasdaq "MSFT" @microsoft) enables digital transformation for the era of an intelligent cloud and an intelligent edge. Its mission is to empower every person and every organization on the planet to achieve more. SOURCE Microsoft Corp.	https://www.prnewswire.com/news-releases/pg-and-microsoft-co-innovate-to-build-the-future-of-digital-manufacturing-301563317.html	2022-06-08T12:05:52	en	0.918502
New Status Incentivizes Microsoft Sales Teams to Sell Altoura with Its Mixed Reality Portfolio SEATTLE, June 8, 2022 /PRNewswire/ -- Altoura today announced it has achieved Microsoft's Azure IP Co-Sell Incentivized status, extending an already strong relationship to include a joint selling motion. Microsoft sellers around the globe are now incentivized to sell Altoura, the leading SaaS productivity platform for spatial work. Altoura is now available on the Microsoft Azure Marketplace, and the two organizations will begin jointly selling mixed reality solutions to customers looking to transform their industry and internal workflows to increase productivity. Altoura helps organizations transform their physical equipment and environments into digital (3D) assets and then make them immersive, interactive, and collaborative. With Altoura, business-critical workflows that once required a physical presence—such as employee training, facilities design and planning, and product demos—can be completed more efficiently as immersive workflows from any location. For example, Altoura customers report that the ability to train employees in a realistic virtual environment before they show up to work onsite in their physical environment reduces training time by more than 70%, accelerating time to productivity and eliminating the need for costly instructor-led training. "We are one hundred percent complimentary to Microsoft mixed reality solutions, and we work closely with Microsoft to help customers become more productive and differentiated," said Jamie Fleming, CEO of Altoura. "Now with Co-sell Incentivized status, we will expand Altoura's commercial reach in the enterprise significantly." Altoura is the pioneer of interactive digital twin technology and maker of the productivity platform for spatial work. Altoura transforms physical assets into 3D models and provides a no-code platform to transform them into immersive, interactive, and collaborative workflows such as immersive training and real estate design visualization. Altoura is a Gold member of Microsoft's Mixed Reality Partner Program and a strategic partner with Meta, Unity, Insight, and leading systems integrators. With a large and growing base of Fortune 500 customers, Altoura is the #1 platform for Manufacturing, Retail, Healthcare, Transportation, and Corporate Real Estate teams that want to empower their workforce with the tools to be productive from anywhere. To learn more, please visit altoura.com. View original content: SOURCE Altoura	https://www.wlbt.com/prnewswire/2022/06/08/altoura-achieves-microsoft-co-sell-incentivized-status/	2022-06-08T12:05:54	en	0.936601
DOYLESTOWN, Pa., June 8, 2022 /PRNewswire/ -- Antios Therapeutics, Inc. (Antios), a clinical-stage biopharmaceutical company developing innovative therapies to advance treatments that can provide a bridge to a cure for chronic hepatitis B virus (HBV), today announced the acceptance of oral presentations highlighting ATI-2173, Antios' lead therapeutic HBV candidate and the only Active Site Polymerase Inhibitor Nucleotide (ASPIN) for HBV in clinical development, and ATI-1428 and ATI-1645, candidates from Antios' 4th generation capsid assembly modulators (CAM) program. These presentations will be given at the European Association for the Study of the Liver's International Liver Congress 2022 (EASL ILC 2022), taking place June 22 – 26, 2022 at the ExCeL London Exhibition Centre in London, UK. Antios will be presenting the 90-day, Phase 2a study of ATI-2173 in combination with tenofovir disoproxil fumarate (TDF). This double-blind, randomized, placebo-controlled study of 20 adult patients was designed to assess the efficacy and safety of 25 and 50 mg doses of ATI-2173 daily for 90 days in combination with TDF compared with TDF plus placebo (control) in chronic HBV-infected subjects. The primary endpoints included the percentage of patients experiencing adverse reactions and time to HBV viral load relapse. In addition to adverse reactions, as a part of the primary safety endpoint, the safety evaluations recorded off-treatment ALT flares in all treatment groups. Antios will also present preclinical data from ATI-1428 and ATI-1645, which are in investigational new drug enabling development. These candidates are class II CAMs with a novel and unique ultra-potent mechanism of action design that may provide for a more targeted and beneficial antiviral response by the immune system. To date, data in a transgenic mouse model for both compounds provide initial evidence for potent in vitro and in vivo activity, an excellent pharmacokinetic profile, and no accumulation of empty capsids in the hepatocellular cytoplasm. "We see ATI-2173 as a bridge to a cure – an important first step in the ultimate search for a cure for HBV," said Greg Mayes, Chief Executive Officer of Antios. "To date, the data have been encouraging, indicating that combining ATI-2173 with a nucleoside analogue such as TDF in a simple, once-a-day regimen has the potential to completely shut down HBV polymerase activity and viral replication. We look forward to presenting our Phase 2a data, as well as the initial data from our CAM program, at the upcoming International Liver Congress." Title: Sustained 12-week off treatment antiviral efficacy of ATI-2173, a novel active site polymerase inhibitor nucleotide, combined with tenofovir disoproxil fumarate in chronic hepatitis B patients, a phase 2a clinical trial (#296) - Author/Presenter: Douglas Mayers, M.D. - Presentation Type: Oral Presentation - Date/Time: June 25, 2022, at 9:15am BST Title: Novel ultra-potent capsid assembly modulators prevent abnormal accumulation of empty capsids and associated T-cell mediated liver injury in a mouse model of hepatitis B virus infection (#291) - Author/Presenter: Luca Guidotti, M.D., Ph.D. - Presentation Type: Oral Presentation - Date/Time: June 25, 2022, at 5:30pm BST ATI-2173, Antios Therapeutics' lead once-daily, oral drug candidate for treating HBV, is an investigational phosphoramidate prodrug of clevudine monophosphate. ATI-2173 has the potential, if approved, to be a bridge to a potential cure for HBV. It is the only Active Site Polymerase Inhibitor Nucleotide (ASPIN) for HBV in clinical development, and its mechanism of action is designed to be complementary to other approaches that also seek to achieve a functional cure. ATI-1428 and ATI-1645 are 4th generation, class II capsid assembly modulators (CAMs), both with a novel and unique ultra-potent mechanism of action design that may provide for a more targeted, productive antiviral response by the immune system. Derived from a novel chemical scaffold, these CAMs have shown strong in vitro and in vivo activity in a transgenic mouse model of HBV infection. As CAMs with an ultrapotent design inducing no accumulation of empty capsids based on an initial preclinical mouse study, ATI-1428 and ATI-1645 represent promising candidates for clinical development and have entered investigational new drug enabling development. ATI-1428 and ATI-1645 were acquired by Antios in November of 2021 from San Raffaele Hospital (OSR), Istituto Nazionale Genetica Molecolare (INGM), and IRBM/Promidis, a collaboration of Italian research institutes and a global contract research organization. Hepatitis B is a potentially life-threatening liver infection caused by HBV. HBV can cause chronic infection, which leads to a higher risk of death from cirrhosis and liver cancer. Chronic HBV infection represents a significant unmet medical need. The World Health Organization estimates that up to 300 million people worldwide suffer from chronic HBV infection, while other estimates indicate that approximately two million people in the United States suffer from chronic HBV infection. Approximately 900,000 people die every year from complications related to chronic HBV infection despite the availability of effective vaccines and current treatment options. Antios Therapeutics is a clinical-stage biopharmaceutical company focused on the development of innovative therapies to treat and cure viral diseases. Its lead drug candidate ATI-2173 – the only Active Site Polymerase Inhibitor Nucleotide (ASPIN) for HBV in clinical development – has the potential, if approved, to become a potential bridge to a cure for chronic HBV. Antios is also developing a novel series of 4th generation capsid assembly modulators (CAMs) to further expand Antios' portfolio of differentiated molecules in the HBV space. HBV is a major unmet global health problem affecting up to 300 million people worldwide, more than hepatitis C and HIV combined. For more information, please visit www.antiostherapeutics.com. View original content to download multimedia: SOURCE Antios Therapeutics	https://www.wlbt.com/prnewswire/2022/06/08/antios-therapeutics-announces-oral-presentations-ati-2173-ati-1428-ati-1645-hepatitis-b-virus-programs-easl-international-liver-congress-2022/	2022-06-08T12:06:00	en	0.907365
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British Superbikes British Superbikes 2022 - 'Unbelievable!' - Bradley Ray takes stunning victory at Donington Park British Superbikes 2022 - 'Unbelievable!' - Bradley Ray takes a stunning victory at Donington Park with some wild celebrations afterwards. Stream top superbikes action live on discovery+ and eurosport.co.uk 00:01:22, an hour ago	https://www.eurosport.com/british-superbikes/donington-park-gp/2022/british-superbikes-2022-unbelievable-bradley-ray-takes-stunning-victory-at-donington-park_vid1759052/video.shtml	2022-10-02T18:16:11	en	0.811268
British Superbikes British Superbikes 2022 - Watch dramatic final lap as Tom Sykes seals double at Donington Park British Superbikes 2022 - Watch the dramatic final lap as Tom Sykes seals an impressive double at Donington Park. Stream top superbikes action live on discovery+ and eurosport.co.uk 00:02:08, an hour ago	https://www.eurosport.com/british-superbikes/donington-park-gp/2022/british-superbikes-2022-watch-dramatic-final-lap-as-tom-sykes-seals-double-at-donington-park_vid1758964/video.shtml	2022-10-02T18:16:18	en	0.868184
Acetaminophen during pregnancy may be linked to attention and sleep problems in young children: New study Taking the pain medication acetaminophen, also known under the brand name of Tylenol, during pregnancy may be associated with child behavioral issues at three years old. That's according to a new report published in the journal PLOS Medicine. "Acetaminophen is commonly used during pregnancy to treat a variety of ailments, but evidence is emerging that shows acetaminophen may be associated with developmental concerns among children," said lead author Kristin Sznajder, assistant professor of public health sciences at Penn State College of Medicine. "Our research found that acetaminophen use during pregnancy increased the risk for attention and sleep problems among young children by more than 20%," she told Fox News Digital. Here are more details. What is acetaminophen? Acetaminophen is often taken as an over-the counter medication to reduce pain and fever, according to the U.S. Food & Drug Administration (FDA). It's also a prescription medication. The FDA notes that acetaminophen "is found in hundreds of medicines including those used for colds, flu, allergies and sleep." Approximately 65%-70% of pregnant women have reported using the pain medication during pregnancy, according to multiple reports. "Although acetaminophen has been shown to cross the placental barrier and therefore may directly impact fetal development, the mechanisms of action for the effect of acetaminophen on fetuses are unknown," the study said. The researchers from Penn State reviewed data from the First Baby Study, which is a prospective study designed to examine the impact of a mother’s mode of delivery on childbearing by following more than 3,000 women who delivered babies from 2009 to 2011 in multiple hospitals in Pennsylvania. For this study, the researchers studied 2,423 mother-child pairs, in which women completed a "prenatal stress inventory" and reported their medication use during their third trimester. The study's methods The participants were asked what prescription and non-prescription medications (other than vitamins) that they took occasionally during pregnancy. When their child turned three years old, they completed the Child Behavior Checklist (CBCL), which "has been widely used in studies of neurodevelopmental and behavioral outcomes in young children," per the study. The women completed the 99-item CBCL questionnaire that asked them to rate their child using a three-point scale on a variety of behaviors, such as restlessness, avoiding eye contact and not wanting to sleep alone. The mothers were interviewed at baseline to evaluate for depression and the level of stress during pregnancy. The results of the study The study found that approximately 42% participants reported using acetaminophen during pregnancy, with a third of women going through labor induction and 29.4% undergoing a Cesarean delivery. The women who used acetaminophen were also more likely to have consumed alcohol during pregnancy, have private insurance and be non-Hispanic white. These women were more likely to be diagnosed with anxiety or depression before their pregnancy and were more likely to report high levels of stress during their pregnancies. They were also more likely to have ingested other non-prescription drugs in addition to acetaminophen, compared with women who did not take acetaminophen. COW-CUDDLING AS STRESS RELIEF: IT'S ‘NATURALLY RELAXING,’ SAYS AN ANIMAL SANCTUARY When the study analyzed the data without controlling for confounding variables, it found "acetaminophen use was associated with higher scores in three areas: [children who are] withdrawn, [have] sleep problems and [have] attention problems." But after the study accounted for variables that could confound the results — such as stress during pregnancy — the researchers found the children of women who used acetaminophen during pregnancy were significantly more likely to have sleep problems and attention problems compared to the children of women who did not take acetaminophen during pregnancy. OHIO WOMAN'S SECOND BABY AS ‘A RESULT OF CO-SLEEPING’: WHAT IS CO-SLEEPING? The authors noted that the association between acetaminophen use and adverse child behavioral outcomes was "mitigated" after controlling for the participants’ stress — which suggests that stress and the use of acetaminophen may independently affect behavioral outcomes in children. The study's limitations The study noted several limitations, including not determining the dose or frequency of use of acetaminophen among the participants’ pregnancy and also not stratifying the use of acetaminophen by trimester. The researchers may have also underestimated acetaminophen use among the participants because the women were only asked about their medication history at one time period during their pregnancy. The study also only assessed the child’s behavior via the mother's observations and impressions — and not via a trained psychologist. This study concluded in its findings "an association between acetaminophen use and child behavioral problems at the age of three years." Health care professionals should balance the benefits with the risks in recommending acetaminophen during pregnancy, the authors suggested. Is acetaminophen safe to use during pregnancy? The FDA is aware of previous research that has shown an association between acetaminophen and the risk of attention deficit hyperactivity disorder (ADHD) in children born to women who took the pain medication during pregnancy. CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER The agency reviewed the research — but because of potential limitations in design and sometimes conflicting results, it has not found a reliable conclusion, according to its website. "Pregnant women should always consult with their health care professional before taking any prescription or OTC medicine," the FDA said. "Women taking pain medicines who are considering becoming pregnant should also consult with their health care professionals to discuss the risks and benefits of pain medicine use."	https://www.fox29.com/news/acetaminophen-during-pregnancy-may-be-linked-to-attention-and-sleep-problems-in-young-children-new-study	2022-10-02T18:16:18	en	0.97191
Monkeypox outbreak may have peaked in US, but still widespread: officials Some U.S. health officials are conceding that monkeypox is probably not going away anytime soon. The disease’s spread is slowing but the virus is so widespread that elimination is unlikely, the Centers for Disease Control and Prevention said. That conclusion was in a recent CDC report, and echoed Friday by Marc Lipsitch, director of science in the agency's disease-forecasting center. Lipsitch hesitated to say monkeypox is permanently here to stay, but he said it stands to be a continuing threat for the next few years. "It's in many geographic locations within the country" as well as in other countries, Lipsitch told The Associated Press. "There's no clear path in our mind to complete elimination domestically." READ MORE: US health officials warn monkeypox could mutate to resist antiviral drug Tpoxx The virus has mainly spread among gay and bisexual men, though health officials continue to stress that anyone can be infected. It's important that people at risk take steps to prevent spread and that vaccination efforts continue, Lipsitch said. The CDC report contained some good news: The U.S. outbreak seems to have peaked in early August. The average number of daily cases being reported — fewer than 150 — is about a third what it was reported in the middle of the summer, and officials expect the decline will continue for at least the next several weeks. A sign announcing monkeypox vaccination is setup in Tropical Park by Miami-Dade County and Nomi Health on August 15, 2022 in Miami, Florida. (Photo by Joe Raedle/Getty Images) Lipsitch attributed the good news to increasing vaccinations, cautious behavior by people at risk and infection-derived immunity in the highest risk populations. Dr. Tom Inglesby, director of the Johns Hopkins Center for Health Security, agreed that it's unlikely that spread of monkeypox will stop in the U.S. anytime soon, but he said it's still possible in the long term. If domestic transmission were stopped, infections may still continue if people catch the virus while traveling internationally, he said. But the declining cases makes it seem like "we’ve turned a real corner." "The efforts underway are succeeding, and should be continued, if not intensified," he said. With case numbers going down, this is a good time for local health departments to take a new stab at doing intensive contact tracing to try to stop chains of transmission, he said. Monkeypox is endemic in parts of Africa, where people have been infected through bites from rodents or small animals, but it wasn’t considered a disease that spreads easily among people until May, when infections emerged in Europe and the U.S. READ MORE: Owners spread monkeypox to their dog, doctors report There have been more than 67,000 cases reported in countries that have not historically seen monkeypox. The U.S. has the most infections of any country — more than 25,600. One U.S. death has been attributed to monkeypox. More than 97% of U.S. cases are men. The vast majority have been men who reported recent sexual contact with other men. Though cases have been declining, the proportion of new cases that have information about recent sexual contact is also down, officials said. That's causing a growing blind spot about how the virus may be spreading, Lipsitch noted.	https://www.fox29.com/news/monkeypox-outbreak-may-have-peaked-us-but-widespread-officials	2022-10-02T18:16:24	en	0.970925
British Superbikes: 'Best win of the year for me!' - Bradley Ray reacts to inspired triumph at Donington Park British Superbikes: 'The best win of the year for me!' - Bradley Ray reacts to his inspired triumph at Donington Park. Stream top superbikes action live on discovery+ and eurosport.co.uk	https://www.eurosport.com/british-superbikes/donington-park-gp/2022/british-superbikes-best-win-of-the-year-for-me-bradley-ray-reacts-to-inspired-triumph-at-donington-park_vid1759055/video.shtml	2022-10-02T18:16:24	en	0.898549
Leeds and Aston Villa played out a scrappy 0-0 draw at Elland Road which will do little to appease either club's fanbase. The result sees Jesse Marsch's side preserve their unbeaten home record this season and move up into 12th. For Villa, they remain on eight points in 14th. Ad The first half was a physical affair with 18 fouls and four yellow cards, but Villa had the first goalscoring opportunity, which Ollie Watkins squandered in the 15th minute when his low driven effort from close range was parried away by Illan Meslier. Premier League Tottenham turned up for the derby, Arsenal fell apart - The Warm-Up Eight minutes later and Rodrigo had Leeds' best chance of the half as he turned and struck a left-footed effort on goal which flew just wide of Emiliano Martinez's left post. The half descended into an attritional contest with referee Stuart Attwell appearing at times to lose control of the match, but Watkins came close to scoring again for Villa shortly before the break when his low shot looking for the bottom corner was saved by Meslier's feet. Leeds were quickly reduced to 10 men after the break. Luis Sinisterra was shown a second yellow card in the 47th minute for needlessly blocking a Douglas Luiz free-kick without giving him 10 yards of space. Philippe Coutinho almost broke the deadlock moments later when his spectacular acrobatic volley beat Meslier but clattered off the post. Philippe Coutinho of Aston Villa during the Premier League match between Leeds United and Aston Villa at Elland Road on October 2, 2022 in Leeds Image credit: Getty Images Substitute Patrick Bamford forced Martinez into a smart reflex save from a tight angle in the 76th minute, while John McGinn made a timely block to deny Mateusz Klich's close range shot in injury time, but ultimately neither side could find the vital goal they craved. TALKING POINT - LEEDS LACK CUTTING EDGE Leeds were perfectly content to turn the game into a physical battle, but too often they resorted to hopeful shots from outside the box to try and find a breakthrough in the match. Bamford made a meaningful impact when he came off the bench for the hosts and Marsch will undoubtedly be hoping that the striker can get back to full fitness as quickly as possible. PLAYER OF THE MATCH - ILLAN MESLIER The French goalkeeper did look nervy when he came out for crosses - a familiar characteristic of his game - but his shot stopping was faultless and he pulled off key saves to deny Ollie Watkins from finding the net. PLAYER RATINGS Leeds: Meslier (8), Kristensen (6), Koch (6), Cooper (6), Struijk (6), Adams (5), Roca (5), Sinisterra (3), Aaronson (5), Harrison (5), Rodrigo (6) Subs: Firpo (5), Ayling (5), Bamford (7), Klich (N/A), Summerville (N/A) Aston Villa: Martinez (6), Young (6), Konsa (6), Mings (5), Augustinsson (4), Luiz (6), Ramsey (6), McGinn (6), Coutinho (7), Bailey (5), Watkins (6) Subs: Bednarek (6), Buendia (5), Ings (N/A) KEY MOMENTS 15' - CHANCE FOR VILLA! Watkins gets a low driven shot away inside the box but Meslier is able to parry it away. Coutinho looks set to turn in the rebound but he loses his footing and the ball lands into the grateful arms of the Leeds goalkeeper. That's the closest we've come to a goal so far. 21' - BIG CHANCE FOR LEEDS! Sinisterra skips by Young and his dangerous low cross from the left flank looks to be on a plate for Rodrigo who slides in to try and meet it at the near post, but he cannot quite reach it! The Leeds fans are roaring their side on. 40' - GOOD SAVE FROM MESLIER! Young slots a ball through into the path of Watkins. He gets a low shot on goal looking for the bottom corner, but Meslier saves with his feet! 47' - SECOND YELLOW FOR SINISTERRA! Sinisterra has been sent off! Referee Attwell shows him a second yellow for intentionally blocking a free-kick from Luiz before he is given ten yards of space. Leeds down to ten men! 49' - COUTINHO HITS THE POST! How did that not go in!? Coutinho acrobatically strikes a right-footed volley on goal which he looks to curl into the top corner, but it crashes off the post! It was a great effort, but Leeds are saved by the woodwork! 76' - GOOD SAVE FROM MARTINEZ! Bamford drives into the Villa box and fires a shot on goal from a tight angle. He does well to get a shot away and it forces Martinez to parrty it away before Firpo makes a timely challenge to stop Aaronson from turning in the rebound. 90+3' HEROIC BLOCK FROM MCGINN! Bamford storms into the box. He loses his footing and lays it off to Klich but his goalbound shot is blocked by McGinn! Premier League Aston Villa complete permanent signing of Coutinho from Barcelona Transfers Pogba in line for shock Premier League switch - Paper Round Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/football/premier-league/2022-2023/leeds-v-aston-villa-premier-league-live_sto9166240/story.shtml	2022-10-02T18:16:31	en	0.948454
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This is a carousel. Use Next and Previous buttons to navigate Storms should never be taken lightly. Hurricane Ian is a fresh reminder of what we know too well, that nature’s beauty can turn savage when the skies darken and the winds pick up. One such catastrophic event brought out the worst the elements can inflict on man, followed by the best of man helping his fellow man. All within the same coastal community. Galveston, Texas, was a bustling place in the summer of 1900. A 19th century boomtown, its mushrooming population pushing 40,000 made it the Lone Star State’s fourth-largest city. Snuggled alongside the Gulf of Mexico, it was home to one of America’s leading ports. International trade flourished so much that its downtown, known as The Strand, was nicknamed “the Wall Street of the Southwest.” Galveston’s future looked dazzlingly bright as the 20th century dawned. Until the weather turned cloudy. At first, it promised to be just another storm. The city had seen — and survived — its share of them over the years. But it quickly became apparent this one was much more than a typical storm. The hurricane that made landfall at Galveston around 8 p.m. Sept. 8, 1900, didn’t have a name; the National Hurricane Center wouldn’t start identifying them that way for 50 years. But it didn’t need one. Because when it was over, the Galveston Hurricane had notched its place in the record books as the worst national disaster in U.S. history. We’ll never know how many people died that Saturday night. Historians generally place the death toll at 8,000, with some estimates going as high as 12,000. The city was flooded by up to 12 feet of water. About 7,000 buildings were destroyed, more than half of them houses. The tragedy was enough to drive some surviving businesses to nearby Houston. Others hung on, determined to somehow claw their way back to normalcy. And amid all the wreckage and ruin and waterlogged streets, an energetic rabbi saw an incredible opportunity. Henry Cohen was a 37-year-old rabbi at Galveston’s Congregation B’nai Israel. Part scholar, part community activist, part writer, he was always looking for ways to make things better for others. And he knew Galveston offered a golden chance for Jews looking to start over in this country. He had caught the vision of Jacob Schiff, himself a Jewish immigrant who had struck it rich in business in New York and wanted to assist Jews coming to the United States. It was a particularly tough time to be Jewish in Europe, especially in the Russian Empire, where the czar’s pogroms sent millions of people fleeing for their lives. Many of them wound up in New York City. But that was the problem. So many Jews were arriving in the Big Apple at the start of the 20th century, it was feared Washington might impose immigration quotas and severely restrict the number of new arrivals. Schiff wanted to help those people move into the American interior and put down roots there. And so, the Galveston Movement was born. With the city needing new residents as it was being reborn, Rabbi Cohen and others set about inviting them to their town. Bankrolled by Schiff’s donation of almost $500,000 (nearly $15 million today), volunteers from several Jewish organizations diverted immigrants away from Gotham and sent them to Galveston instead. Between 1907 and 1914, tens of thousands of Jews passed through the city’s port. Many came from Palestine, where they had gone after being driven from their homes in Eastern Europe. Cohen and his allies met them at the docks, helped them navigate the cumbersome entry process, and then steered them to new homes — and new lives — in the recovering city and beyond. There were moments of friction, of course. Some Texans were bewildered to hear their new neighbors speaking Russian, Polish, German, Yiddish and Hebrew, languages they had never experienced before. Some simply couldn’t understand why the immigrants refused to work on Saturdays. And as the new arrivals went into business for themselves and began prospering, some merchants grew jealous. But there were more success stories than failures. The Galveston Movement gradually sputtered out of existence as World War I neared, slowing the tide of Eastern European immigration. Henry Cohen was a respected rabbi emeritus when he passed away at age 89 in 1952. Miles deep in the heart of Texas, mom-and-pop businesses still operate on small-town courthouse squares that were founded by people he helped settle there. Yes, a hurricane can be ferociously ugly. But what came come out of it can be beautiful. J. Mark Powell is a novelist, former TV journalist and diehard history buff. Have a historical mystery that needs solving? A forgotten moment worth remembering? Send it to HolyCow@insidesources.com.	https://www.myjournalcourier.com/news/article/Holy-cow-History-A-hurricane-a-rabbi-and-a-17473333.php	2022-10-02T18:16:35	en	0.980793
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Pep Guardiola thinks his Manchester City side could have scored more in their 6-3 derby victory against Manchester United and that they must strive for “perfection.” City ran riot against United, scoring four goals in the first half through Phil Foden and Erling Haaland. Ad And though they were less impressive in the second half, they added two further goals to their tally to embarrass their cross-town visitors. Premier League Haaland becomes first player to score hat-tricks in three consecutive PL home games "It was really good,” said Guardiola. We scored four goals, and we could have scored more, really. “At half-time, we talked, ‘Let’s continue’, but it was more difficult. They played better in the second half and in the last minutes we were flat, but great victory, it was a good game, and everyone was happy in the stadium. They enjoyed it. We enjoyed it against our rival, Manchester United, so good afternoon for us.” Guardiola also spoke about how his players got the better of Erik ten Hag’s side: "In general, it was really good. How aggressive we were without the ball, they could not play. When they have Lisandro [Martinez], and Bruno [Fernandes], and [Christen] Eriksen and all of them, they have quality. And we saw a little bit of it in a few minutes in the second half. “In the first half, we were there in the turns, we were aware of the spaces, and the quality of players we had up front made the difference.” - 'Unacceptable' – Ten Hag cites Man Utd's 'lack of belief' as reason for heavy Man City loss - Wolves sack Lage after defeat to West Ham - Haaland becomes first player to score hat-tricks in three consecutive PL home games City, who are targeting their fifth Premier League title in six seasons, have always been known to be relentless under Guardiola, and the Catalan spoke about how desire in his team is “non-negotiable". He said: “We can win or lose, but the effort and the desire and helping each other [is important]. But there are many things that we can do better. Some players were not good today and have to improve. "Perfection doesn't exist, it's impossible. But we must try to look there. We did good, we can do better, many, many players had sloppy passes. This is not good. We have to be more consistent. In some areas, we were still not good." On Foden, Guardiola hailed his will to perform well, saying: "He [Foden] deserves to play every time, and then he has quality. He is a young player, and it is a reality. He deserves everything." The manager also spoke highly of summer signing Haaland, simply stating that his career numbers speak for themselves. "He has done this before here," Guardiola said. "It is not our way. [We always] try to help him in our environment. We have this incredible sense that he always looks starving and is so competitive. The numbers are scary, honestly. "He sees 10 players running without the ball with effort for each other so he wants to do it. They visualise it, they see it. It's why we have success in the last few years. Behind it is effort and desire to do it." The two hat-trick heroes both spoke to the media, with Foden jumping at the opportunity to express how proud he is to play for the club, as a local fan. He said: "Obviously, it is a dream come true to play in the derby, being a Man City fan as well. Erling and I have built that connection now, and we are finding each other, and yes, it’s been a pleasure to be a part of the team. "I feel that way [that the team just clicked right from the start]. Our determination, right from kick off, we were right at it and we finished our chances." Haaland echoed Guardiola’s sentiments that his side could have scored more, saying: "It could've been more and in the second half we should've been tighter, worked a bit harder, because it was a bit sloppy at times. We lost the second half and this is not good, so we still have to work. “It's these games I want to play in. These are the best games where there's a bit extra.” Premier League 'I almost can't believe what I'm watching' - Keane rips into 'sloppy' Man Utd Premier League Man City have a succession plan to follow me, says Guardiola Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/football/premier-league/2022-2023/pep-guardiola-praises-manchester-city-s-desire-in-their-stunning-6-3-derby-win-over-manchester-unite_sto9169465/story.shtml	2022-10-02T18:16:37	en	0.990091
"Bros," the latest romantic comedy to hit theaters, is absolutely revolutionary. And totally conventional. It's a film where both extremes can be true at the same time. The revolutionary part comes from it being the first gay rom-com produced and distributed by a major American studio. And yet it hews very closely to the classic rom-com formula, right down to one of the star-crossed lovers suddenly realizing he's in love and sprinting to reunite with the other as music swells. That's the genius of "Bros" — telling LGBTQ stories and wrapping them in a familiar storyline to which everyone can relate. At one point, we see our hero watching "When Harry Met Sally" and we quietly cheer as the universe of rom-coms just got another satellite. Some people may complain that it fits too neatly into the straight-people film formula, but revolutions weren't built in a movie. Billy Eichner stars as Bobby Lieber, a slightly nerdy gay podcaster-turned-museum executive who has hit the age of 40 without having had a serious romantic relationship. The script by Nicholas Stoller and Eichner leans into the schtick Eichner has built as a loud, opinionated comic on "Billy on the Street" but creates room for a wounded, insecure hero. Eichner is navigating the fraught world of modern dating in the New York City gay community, which includes graceless app hookups, steroid use, dance-club ogling, legions of commitment-phobes and an emphasis on the physical and superficial — so just like straights! When sparks fly between him and a hunky meathead — played understated and soulfully by Luke Macfarlane — it's clear that opposites attract. Our hero has a sunken chest, an unwavering belief that Abraham Lincoln was a closeted gay man and a high voice; the muscly hunk is a fan of Garth Brooks, hockey and "The Office." Yet he also can see to the core of our hero: "Getting angry at things is your brand," he tells him. The filmmakers make sure "Bros" isn't a sanitized view of gay love, earning an R-rating for nudity, sex, lusty kissing and group encounters like throuples and a very funny, awkward four-way with a random guy named Steve. In many parts, it feels very much like every lingering, passionate kiss is blissfully punching through some sort of wall. Stoller, who also directs, and Eichner load the script with plenty of gentle humor at non-gay targets. "Gay sex was more fun when straight people were uncomfortable," says one character. And a couple of recurring gags involve straight actors winning awards for playing gay — Benedict Cumberbatch, look out! — and the Hallmark Channel's supposed embrace of non-hetero themes, like with the fictional bisexual titles "Christmas With Either" and the group rom-com "A Holly, Polly Christmas." Gay stereotypes also get celebrated and pierced — endless voguing, Grindr photos, "Schitt's Creek" love, Barbra Streisand adoration and internal divisions among the LGBTQ community. Deborah Messing from "Will & Grace" makes a hilarious cameo ("I am not every gay man's best friend!" she wails) and Kaitlin Jenner is mocked as a "trans-terrorist." A key moment is when Eichner pierces the inclusive slogan "Love Is Love" with his retort "No, it's not." Gay love, he says, has different obstacles and complications and ramifications. In his love affair, identity becomes the drama. Bobby is fiercely proud of being gay and not apologizing for it, while his love interest is more quiet about his sexuality, fatefully asking his lover to tone it down one night while meeting his parents. "A little less yourself," he explains. "I want them to like you." Everyone will understand what that means. That's straight out of a John Hughes rom-com. It's not a perfect film — the first half sags a little, the jump in Bobby's career is jarring and some soliloquies land with a thud — but name us a perfect rom-com. This one has what the best have: heart, good faith and good old-fashioned love. Welcome, "Bros," to the canon. "Bros," a Universal Pictures release that hit theaters Friday, is rated R for strong sexual content, some drug use and language throughout. Running time: 115 minutes. Three and a half stars out of four.	https://www.myjournalcourier.com/news/article/Review-Bros-makes-rom-com-history-and-then-17475333.php	2022-10-02T18:16:42	en	0.957918
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Erik ten Hag said he was “surprised” by his team’s performance during their 6-3 derby loss to Manchester City, and questioned why his players had shown a "lack of belief". The derby could not have started off worse for United, with City scoring four goals in the first half, two each from Phil Foden and Erling Haaland. Ad Antony got one back in the second half before Haaland and Foden completed their hattricks. Premier League ‘Could have scored more’ – Guardiola praises Man City's desire in stunning derby win United then scored two consolation goals late on through Anthony Martial. Speaking to Sky Sports after the defeat, Ten Hag said: "I am surprised why we didn't bring it on the pitch. "It’s four weeks ago [United’s last league game], but I have seen a different team, a different spirit and a different vibe. Today we were not convincing, we were not on the front foot and we were not brave in possession. "I will show the team tomorrow we could have been on the front foot. In the first goal, we won the ball and could have created a chance and gave it away. That is unacceptable." 'He was born with it' - Guardiola on Haaland's performance in United demolition - Man City have a succession plan to follow me, says Guardiola - Haaland becomes first player to score hat-tricks in three consecutive PL home games - 'I almost can't believe what I'm watching' - Keane rips into 'sloppy' Man Utd When asked why things had gone so wrong, Ten Hag responded: “It’s difficult to find out [what happened] straight after the game. I need to talk to my players. They know they can do better. If you don’t fight, and we didn’t, you’ll get a problem against a team like Man City. “I don’t think you can compare this [to the Brentford game]. Against Brentford, we didn’t run; today, we didn’t follow the principles; we were indisciplined. Once again, it was a lack of belief.” Despite City’s scintillating display, the Dutch manager emphasised that his own’s side performance was the main reason for the loss. “When you don't believe on the pitch, then you can't win games, that is unacceptable. We get undisciplined at following rules, and you get hammered, that's happened today. "For me, it was a surprise. We were not on the front foot, we were not brave on the ball, and there were spaces to play, but we were not brave enough. "All the credit to City, but it's nothing to do with City, our performance was not good. It had to do with the belief as individuals and as a team. MANCHESTER, ENGLAND - OCTOBER 02: Phil Foden of Manchester City celebrates their sides fourth goal with team mates Sergio Gomez and Erling Haaland during the Premier League match between Manchester City and Manchester United at Etihad Stadium on October 0 Image credit: Getty Images "From the first minute I felt it, and at half-time, we changed things, and we changed attitude. We saw a different Manchester United after half-time, and we scored goals, we created some more. On the ball we were more brave, we came in the opponent's half, and we scored three goals. "In this moment I can't think about positives. We let our fans down, we let ourselves down and we're hugely disappointed." Christian Eriksen also spoke to the media after the match, saying that the defeat “came very heavy.” “Everyone feels it was a very bad day at the office," the Dane said. "We started on the wrong foot. They had chances straight from kick-off. We can only blame ourselves. "We missed a bit of courage to play out from the back, and we let them be at their strength. The main focus from this game will be on ourselves. "There are a lot of things we need to change and a lot of things we need to do better. Today was far from acceptable from what we should be doing." Ten Hag will hope that he can shape up his team in time for their mid-week Europa League match against Omonia before they face Frank Lampard’s Everton on Merseyside next weekend. Premier League Haaland becomes first player to score hat-tricks in three consecutive PL home games Premier League 'I almost can't believe what I'm watching' - Keane rips into 'sloppy' Man Utd Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/football/premier-league/2022-2023/unacceptable-erik-ten-hag-cites-man-united-s-lack-of-belief-as-reason-for-6-3-derby-loss-against-man_sto9169419/story.shtml	2022-10-02T18:16:44	en	0.985724
This is a carousel. Use Next and Previous buttons to navigate The nostalgia for "Hocus Pocus" has always been a bit of a mystery to me. There is nothing new about kids loving mediocre films and carrying that soft spot into adulthood, but I was in the right demographic when "Hocus Pocus" came out in the summer of 1993 (age 9, approaching third grade) and remember it being just OK. This is not a testament to my taste at the time, when I thought "Grease 2" was one of the best movies ever, but more so indicative of the undeniable averageness of "Hocus Pocus." I don't think it was just me, either. Aside from Sarah Jessica Parker's "Amok! Amok! Amok!" entering our vernacular, it was not a movie any of my peers were eager to watch again. And yet, much to my bewilderment, "Hocus Pocus" became a thing over the years. My best guess is it was some combination of its relentless availability crossed with a lack of PG-rated Halloween content. Plus, there is the intro-to-camp factor of Parker, Bette Midler and Kathy Najimy as singing sisters bent on eating children to preserve their youth. Regardless, a straight-to-Disney+ sequel made 30 years later seemed like a cynical endeavor at best. So it was a pleasant surprise to find that " Hocus Pocus 2 " actually is pretty fun. Set in a Stars Hollow-like Salem, it's the perfect Disney+ movie — seasonally appropriate entertainment that, for at least one night, may save a family from the doom of endless scrolling and indecision. With a lively, witty script by Jen D'Angelo, "Hocus Pocus 2" finds the Sanderson sisters Winifred (Midler), Sarah (Parker) and Mary (Najimy) unleashed on their present day town once more. This time it's some coven-curious teenage girls Becca (Whitney Peak) and Izzy (Belissa Escobedo) who accidentally resurrect them and then try to outwit them where they can, leading to an amusing sequence in a drug store in which the always vain Sandersons sample the serums in the beauty aisle. Midler, Parker and Najimy are all once again game to ham it up for the audience (and sometimes no one but themselves) with spells, songs and dances. But they are only part of this strangely amusing brew, with well rounded teen characters, and a very strong comedic supporting cast including Sam Richardson, as the owner of the local occult shop; Tony Hale, as the mayor and a witch trial era reverend; and Doug Jones as a "good zombie." Hannah Waddingham from "Ted Lasso" also has a far-too-short cameo as another witch. Special mention should be made of the three actors who play the young Sanderson sisters, Taylor Henderson as Winifred, Nina Kitchen as Mary and Juju Journey Brener as Sarah, who do a lovely job of embodying their adult counterparts in a brief origin story. But the heart of the film is the teen girls, who have their own issues aside from stopping the Sanderson sisters from becoming all powerful — Becca and Izzy are grappling with a life in which their third, Cassie (Lilia Buckingham), has turned her attentions away from their amateur-witching and to her jock boyfriend. Peak, who played Idris Elba's daughter in "Molly's Game," is a standout. Directed by Anne Fletcher, "Hocus Pocus 2" goes down easy — though by the time the entire town breaks out into a dance to "One Way or Another," you may be ready for the film to get where it's going. Still, it's a fun enough ride for a fall night. "Hocus Pocus 2," a Disney+ release streaming Friday, is rated PG by the Motion Picture Association for "action, some language, macabre/suggestive humor." Running time: 104 minutes. Two and a half stars out of four.	https://www.myjournalcourier.com/news/article/Review-The-witches-return-in-lively-Hocus-Pocus-17475429.php	2022-10-02T18:16:48	en	0.968971
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Bruno Lage has been sacked by Wolves. The news comes after the club’s poor start to the season, with chairman Jeff Shi taking action the day after the team’s 2-0 defeat to West Ham. Ad Wolves chairman Shi said in a statement posted on the club's website: “Bruno is an excellent coach, a hardworking and dedicated manager, and a warm, wise and honest man. Premier League Bowen and Scamacca on target as West Ham cruise past Wolves “He and his staff have been a pleasure to work with throughout their time at Wolves, so it is with much sadness that we have had to make what has been a difficult decision. “I honestly have no doubts about Bruno’s ability, and I’m sure he will succeed elsewhere, however the team’s form and performances over the last few months mean that we have no choice but to act. “On behalf of everyone at Wolves, I would like to place on record our gratitude to Bruno and his coaching team for all their efforts during their time with the club, and wish them the very best for the future.” - Bowen and Scamacca on target as West Ham cruise past Wolves - Haaland becomes first player to score hat-tricks in three consecutive PL home games - Real Madrid sweating over Courtois fitness ahead of El Clasico After the match, which would turn out to be his final one in charge, Lage said: "We will continue to work. I know the fans support us. We try to do our best for them. We're in a bad moment, we don't have goals or victories. "We need to continue to work. I can promise we will work hard every day to bring good games and victories for the team." Under Lage, Wolves have only won once in their last 15 league matches, and they currently find themselves in 18th, behind Crystal Palace on goal difference. Despite Lage being backed with signings such Matheus Nunes and Gonçalo Guedes last summer, Wolves have only scored three league goals this season, one each against Leeds, Newcastle, and Southampton respectively. Shi appointed Lage in June 2021 after the departure of Nuno Espirito Santo. Lage was reportedly Wolves’ first choice at the time due to his style of play and record at Benfica. Wolves confirmed in their statement that club coaches Steve Davis and James Collins would prepare the team this week for the upcoming trip to Chelsea. Transfers Nkunku completes Chelsea medical ahead of transfer - Paper Round Premier League 'He sets the standard' - Man City's captain consistent De Bruyne impresses again Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/football/premier-league/2022-2023/wolves-sack-manager-bruno-lage-after-defeat-to-west-ham-and-with-club-in-premier-league-relegation-z_sto9169197/story.shtml	2022-10-02T18:16:51	en	0.976447
This is a carousel. Use Next and Previous buttons to navigate Gardening naturally lends itself to reusing and recycling — just think about compost and last year’s seed trays. So if there’s a way to reduce trash while saving money on produce, you can count me in. And one of my favorite ways to do both is to regrow vegetables from kitchen scraps. Instead of throwing away or composting the bottoms (or tops) of vegetables when preparing them, you can grow them into leafy greens and other tasty tidbits right on your windowsill. Before I go any further, it’s important to point out that these methods aren’t likely to produce plants that will grow well in your garden, so I don’t recommend replacing your seedlings in this manner. But they are likely to yield a side dish or two, and you can never underestimate the value of a fun project. General tips: Scraps will grow best in a sunny spot. Use lukewarm water, and replace it every day or two to avoid the growth of bacteria. Don’t worry if the submerged portion of your cuttings becomes a bit slimy, but if the whole thing starts to turn brown, toss it in the compost pile and start over. Beets My favorite thing about beets is that one plant provides two sides dishes – the tuberous root and the tasty greens. Although you can’t regrow a beetroot indoors from a cutting, you can certainly generate more leafy greens: Cut off the top 1 1/2 inches from a beetroot and place it cut-side down in a dish that contains just enough water to keep the sliced end submerged. New leaves will sprout from the top within a few days, and you can start harvesting them in a couple of weeks. (This method also works with parsnips and turnips). Celery Cut 3 inches off the bottom of a head of celery, then slice a sliver off the very bottom of the 3-inch segment. Place it right-side up in a shallow container and pour in 2 inches of water. New growth will sprout from the center in just a few days. Scallions Trim the entire white portion off the bottom of a leek or scallion stalk, then place it root-side-down in a jar or glass holding an inch of water. If the stalk outgrows the jar, move it to a larger one. New growth will be harvestable in a couple of weeks. Romaine lettuce Cut 3 inches off the bottom of a head of romaine lettuce, then remove its outermost leaves. Place the 3-inch “heart” in a shallow container to which you’ve added one-half inch of water. Within a week, a sprout will emerge from its center. As it grows, it’s normal for some of the heart’s outer leaves to turn brown. Remove them. When the center growth is large enough for a salad (or sandwich), trim it off and enjoy – then wait for more to grow.	https://www.myjournalcourier.com/news/article/home-regrowing-vegetables-17470824.php	2022-10-02T18:16:54	en	0.91806
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Max Verstappen rued an "incredibly messy" performance at the Singapore Grand Prix on Sunday that thwarted his hopes of securing his second world title. The Red Bull driver needed results to go his way in order to come away with consecutive Formula 1 world championships, but a calamitous end to qualifying on Saturday saw him start the race in eighth. Ad Verstappen then slipped down the pack early on and also found himself off the track midway through the race, but a late charge lifted him up into a seventh-placed finish, beating Lewis Hamilton by a couple of places. Singapore Grand Prix How can Verstappen win the Formula 1 championship at the Singapore Grand Prix? There was some comfort for Verstappen though as the race was won by his Red Bull teammate Sergio Perez. Speaking to Sky Sports after the race, Verstappen admitted that he and his team had underperformed. The 25-year-old Dutchman said: "It’s not where we want to be. Yesterday [Saturday], you put yourself in a spot like that and it can either work brilliantly and you can drive back to the front or it’s very frustrating like we had. "Seventh is better than eighth but it’s not what I’m here for, not with a car like that and what we showed in practice. - Perez wins Singapore Grand Prix but faces investigation for safety car infringement - Perez celebrates 'best performance' after dominant Singapore victory "It’s just incredibly messy." Singapore Grand Prix 'Never acceptable' - Verstappen unhappy to be called in before final qualifying lap Singapore Grand Prix Leclerc claims pole at Singapore Grand Prix, Verstappen in eighth Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/formula-1/singapore-grand-prix/2022/incredibly-messy-max-verstappen-reflects-on-missed-chance-to-win-world-championship-at-singapore-gra_sto9169446/story.shtml	2022-10-02T18:16:57	en	0.957824
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Lewis Hamilton was disappointed to come away with ninth place at the Singapore Grand Prix on Sunday. The seven-time world champion started in third place after a decent showing in qualifying but a lock-up at Turn 7 and a late mistake combined to give him an underwhelming finish. Ad Hamilton has failed to win a Grand Prix this season after struggling with his Mercedes. The car suffered a pronounced problem with the 'porpoising' phenomenon after all car designs were fundamentally overhauled between seasons. Singapore Grand Prix Mercedes fined for ‘inaccurate self-scrutineering form’ amid Hamilton jewellery dispute While those problems have been mitigated by upgrades to the design and a change in rules to reduce the difficulty for all teams, the Mercedes duo of Hamilton and George Russell have struggled to match the pace of the Ferrari and Red Bull teams all year. "I think we started off with a pretty decent weekend and were just really, really unfortunate at the end," Hamilton said to Sky Sports. "It was difficult to overtake and that lock-up into Turn 7 - when those things happen your heart sinks a little bit. - Perez wins Singapore Grand Prix but faces investigation for safety car infringement - 'Incredibly messy' - Verstappen rues missed chance to win world championship - Perez celebrates 'best performance' after dominant Singapore victory "But you get back up again and you try. It wasn't the greatest day, but I'm looking forward to tomorrow. "It all went out the window when I locked up, so my apologies to the team, but we live and learn, and I'll recover." There is no rest for the F1 paddock as they travel to the Suzuka circuit for the Japanese GP next weekend, in a race that could see Max Verstappen wrap up the title. Singapore Grand Prix Leclerc claims pole at Singapore Grand Prix, Verstappen in eighth Singapore Grand Prix Hamilton quickest in FP1 at Singapore GP, Verstappen second fastest Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/formula-1/singapore-grand-prix/2022/really-unfortunate-mercedes-driver-lewis-hamilton-counts-cost-of-mistakes-at-singapore-grand-prix_sto9169505/story.shtml	2022-10-02T18:17:04	en	0.961396
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Ryan Fox landed a one-shot victory at the Alfred Dunhill Links Championship at St Andrews after holding his nerve in the final round. Fox was able to secure the win after he held off both Callum Shinkwin and Alex Noren by a stroke as he finished on 15 under par. Ad Rory McIlroy finished one shot ahead of Daniel Gavins and a shot behind Shinkwin and Noren to come fourth. Alfred Dunhill Links Championship Mansell takes four-shot lead ahead of Alfred Dunhill Links final round Fox has often played at the tournament alongside the late Shane Warne, who he commemorated after his victory. "I felt that Warney was with me this week," the New Zealander said. "You need a little bit of luck in golf, and I felt that he was that today. "He absolutely loved this tournament, and we had an awful lot of fun here over the years. A lot of people missed him this week, including myself but I'm pretty proud to get the job done and remember him like that. - Mansell takes four-shot lead ahead of Alfred Dunhill Links final round - Sanderson Farms Championship : Highlights day 3 - McIlroy struggles and Mansell moves in wild weather at Alfred Dunhill Links Championship "I wouldn't say I came into this week with any good form with a couple of missed cuts and a withdrawal, but I always felt that this week was going to be a little different." On his final round of 66, McIlroy said: "Played well again today. "I didn't make birdie at 14, which sort of halted the momentum I had. It was a bit of a struggle on the way in. Came up two or three short of my target in the end." After Saturday, it had been Richard Mansell who was in the lead after a fine 67, with Fox among the many trailing him, but Mansell struggled to a closing 76 and finished tied for seventh on 11 under. In the decisive round, Fox picked up four birdies on his front nine and three more besides. His three bogeys left him four under for the day. Noren's third successive three-under 69 and Shinkwin's 67 were not enough as Fox made par on the 18th to seal his win. Alfred Dunhill Links Championship 'I will have other chances' - McIlroy's love for St Andrews outweighs Open heartache Alfred Dunhill Links Championship McIlroy struggles and Mansell moves in wild weather at Alfred Dunhill Links Championship Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/golf/alfred-dunhill-links-championship/2022/ryan-fox-wins-alfred-dunhill-links-championship-at-st-andrews-by-one-shot-rory-mcilroy-ties-for-four_sto9169630/story.shtml	2022-10-02T18:17:10	en	0.984584
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Marc-Andrea Huesler clinched his first ATP Tour title at the Sofia Open on Sunday with a surprise victory over Holger Rune. The 26-year-old late bloomer from Zurich battled past the richly-talented Dane in straight sets, 6-4 7-6(8), to claim his maiden singles title with a real flourish in a tense tie-break. Ad The left-hander was competing in his first ATP Tour-level final and showed real poise in tactically outplaying Rune in one hour and 42 minutes. Laver Cup 'It added something special' - Djokovic wants rivals at retirement like Federer Huesler, who has moved up to No. 64 in the ATP live rankings as a result of the triumph, became the first Swiss player to win an ATP Tour title since the great Roger Federer lifted the trophy in Basel three years ago. Despite the in-form Rune throwing everything at him, particularly in the second set, Huesler was left to reflect on a resilient display. "I played a great, great match for sure," he said in his on-court interview. "I am completely taken aback. I am lost for words. it was a great match. I just tried to stay focused, stayed calm and I am just really happy I was able to make it." - Norrie forced to withdraw from Japan Open due to positive Covid-19 test - 'It means a lot for my country' - Sherif makes history for Egypt with Parma Open triumph - Exclusive: Ljubicic reveals what coaching Federer is like, says legend 'is not going anywhere' Huesler 'really thrilled' after winning first ATP title at Sofia Open The win capped a remarkable week for Huesler, who notably overcame rising star from Italy, Lorenzo Musetti, while also defeating Pablo Carreno Busta in what marked his first-ever win over a top-20 player on the tour. Tennis Serena v Sharapova, Federer v Ferrer: Tennis’ most surprising head-to-head records US Open 'I just needed to stop' - Williams opens up about retiring at US Open Share this article Advertisement Ad Advertisement Ad	https://www.eurosport.com/tennis/atp-sofia/2022/marc-andrea-huesler-wins-first-atp-tour-title-in-sofia-with-surprise-victory-over-holger-rune-in-fin_sto9169437/story.shtml	2022-10-02T18:17:16	en	0.962147

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