question
stringlengths 13
189
| answers
dict | id
stringlengths 24
24
| context
null |
|---|---|---|---|
Is the FIP virus thought to be a mutated strain for the Feline enteric Coronavirus?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5e3ebaa348dab47f2600000a
| null |
Which sports have a risk for commotio cordis?
|
{
"answer_start": [
0,
0,
0,
0,
0,
0
],
"text": [
"baseball",
"football",
"soccer",
"cricket",
"hockey",
"lacrosse"
]
}
|
5300aad02059c6d71c000080
| null |
Which type of analysis does DeSeq2 perform?
|
{
"answer_start": [
0
],
"text": [
"differential analysis of RNASeq data"
]
}
|
5fdb41b6a43ad3127800001d
| null |
Is Mical an oxidoreductase?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
62515021e764a53204000018
| null |
Which are the available biomedical text mining tools for the detection of protein-protein interactions?
|
{
"answer_start": [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
],
"text": [
"BioCreative Meta Server",
"Hidden Vector State model",
"iHop",
"LAITOR",
"OntoGene",
"PIE",
"PPInterFinder",
"PPIs",
"TafTalent",
"PolySearch",
"OpenDMAP",
"HAPPI",
"GeneView",
"PPI finder",
"PreBind",
"BioMap",
"eFIP",
"Protopia",
"STRING"
]
}
|
5149aafcd24251bc05000045
| null |
List co-morbidities that may occur together with "Stiff man Syndrome"
|
{
"answer_start": [
0,
0,
0,
0
],
"text": [
"Insulin Dependent Diabetes Mellitus",
"Grave's disease",
"Breast Cancer",
"Dementia"
]
}
|
515df86a298dcd4e5100002e
| null |
What disease does BCG immunotherapy used to treat?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"bladder cancer",
"bladder cancer (NMIBC)",
"high-grade non-muscle invasive bladder cancer (NMIBC)"
]
}
|
60292d191cb411341a00010e
| null |
Is there any software for automated analysis of FISH images?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5311cdcce3eabad021000007
| null |
What is the name of the Cas13 based diagnostic test for the Zika and dengue viruses?
|
{
"answer_start": [
0
],
"text": [
"SHERLOCK (specific high-sensitivity enzymatic reporter unlocking)"
]
}
|
5c92871decadf2e73f000016
| null |
Is there any role for long noncoding RNAs in adipogenesis?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
56d1d56b67f0cb3d66000004
| null |
PBT2 has been tested for which disorder?
|
{
"answer_start": [
0
],
"text": [
"Alzheimer's disease"
]
}
|
54fc91e96ad7dcbc12000001
| null |
RV3-BB vaccine is used for prevention of which viral infection?
|
{
"answer_start": [
0
],
"text": [
"rotavirus disease"
]
}
|
5c6e05f37c78d69471000049
| null |
List major risk factors for Alzheimer's disease.
|
{
"answer_start": [
0,
0,
0,
0,
0,
0
],
"text": [
"Apolipoprotein E4",
"type 2 diabetes",
"Clusterin",
"Hypertension",
"advancing age",
"obesity"
]
}
|
5a9d96564e03427e73000001
| null |
Which Janus kinase does decernotinib target?
|
{
"answer_start": [
0
],
"text": [
"Janus kinase 3 (JAK3)"
]
}
|
5a7610af83b0d9ea6600001a
| null |
Which is the receptor for the immunosuppressive drug cyclosporin A (CsA)?
|
{
"answer_start": [
0
],
"text": [
"cyclophilin"
]
}
|
56f6c11109dd18d46b00000e
| null |
List STING agonists.
|
{
"answer_start": [
0,
0,
0
],
"text": [
"CDN 3'3'-cGAMP",
"dimethylxanthenone-4-acetic acid",
"α-Mangostin"
]
}
|
5c7ab080d774d0424000000b
| null |
What is the method FASP used for?
|
{
"answer_start": [
0
],
"text": [
"proteomic sample preparation"
]
}
|
5509f433c2af5d5b70000008
| null |
Which disease is treated with Fexinidazole?
|
{
"answer_start": [
0
],
"text": [
"human african trypanosomiasis"
]
}
|
5a7373f63b9d13c708000008
| null |
Is a mutation of the ZIKV's membrane protein prM responsible for the microcephaly in new-born infants?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5ac0aee419833b0d7b000004
| null |
What is the target of the drug Olmesartan?
|
{
"answer_start": [
0
],
"text": [
"angiotensin II receptor"
]
}
|
5e808ef4835f4e477700002a
| null |
Tumors of which three organs are classically associated with the multiple endocrine neoplasia type 1 syndrome?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"parathyroid gland",
"pancreas",
"pituitary gland"
]
}
|
51477de5d24251bc05000020
| null |
What are the effects of CAMK4 inhibition?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"Th17 differentiation",
"reduction of Il17 expression",
"decreased activation of cAMP"
]
}
|
5d387360a1e1595105000007
| null |
Which protein is the E3-ubiquitin ligase that targets the tumor suppressor p53 for proteasomal degradation?
|
{
"answer_start": [
0,
0
],
"text": [
"The mouse double minute 2 (mdm2)",
"The human homologue of Mdm2 (Hdm2)"
]
}
|
55058af6f73303d458000004
| null |
Which molecules are targeted by defactinib?
|
{
"answer_start": [
0,
0
],
"text": [
"focal adhesion kinase",
"proline-rich tyrosine kinase-2"
]
}
|
5c6f107c7c78d69471000051
| null |
What is the effect of rHDL-apoE3 on endothelial cell migration?
|
{
"answer_start": [
0
],
"text": [
"Promotion"
]
}
|
6206b5a8c9dfcb9c0900003a
| null |
Has ZP-PTH been tested in a phase II clinical trial?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5e7f69d2835f4e4777000021
| null |
Which is the most important prognosis sub-classification in Chronic Lymphocytic Leukemia?
|
{
"answer_start": [
0
],
"text": [
"The mutational status of the IGHV genes."
]
}
|
51739df58ed59a060a00001c
| null |
What part of the body is affected by Meniere's disease?
|
{
"answer_start": [
0
],
"text": [
"inner ear"
]
}
|
5c5310c37e3cb0e231000010
| null |
What is Contrave prescribed for?
|
{
"answer_start": [
0
],
"text": [
"Obesity"
]
}
|
58a32edd60087bc10a000012
| null |
Which disease is caused by mutations in the gene PRF1?
|
{
"answer_start": [
0
],
"text": [
"haemophagocytic lymphohistiocytosis (HLH)"
]
}
|
6217db1b3a8413c653000027
| null |
Which is the enzymatic activity of the myotubularin family of proteins?
|
{
"answer_start": [
0
],
"text": [
"lipid inositol phosphatase activity"
]
}
|
54d6562c3706e8952800000b
| null |
Have machine learning methods been used to predict the severity of major depressive disorder(MDD)?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5c5215e67e3cb0e231000004
| null |
What molecule is targeted by Avelumab?
|
{
"answer_start": [
0,
0
],
"text": [
"programmed death-ligand 1",
"PD-L1"
]
}
|
5884c72fe56acf517600000f
| null |
Is TNNI3K a cardiac-specific protein?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
551c4ffc6b348bb82c000010
| null |
Is RET the major gene involved in Hirschsprung disease?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5503121de9bde69634000019
| null |
Which proteins act as histone-like molecules in prokaryotes?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"HU",
"IHF",
"H-NS"
]
}
|
52ef7754c8da898910000014
| null |
List 3 apoE mimetics.
|
{
"answer_start": [
0,
0,
0
],
"text": [
"COG133",
"COG112",
"Ac-hE18A-NH(2)"
]
}
|
5c88550075a4a5d219000008
| null |
What is the effect induced by sympathetic nervous system on pupil size?
|
{
"answer_start": [
0
],
"text": [
"pupillary dilatation (increase of the pupil size)"
]
}
|
5547ec32f35db7552600000a
| null |
Is taxilin a cancer marker?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
622dd1433a8413c6530000a5
| null |
Is hydroxyurea usually used to treated infectious disease?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
58dbbdac8acda3452900001e
| null |
What is the molecular function of psoralen photobinding on DNA?
|
{
"answer_start": [
0
],
"text": [
"It intercalates into the double helix."
]
}
|
56c341acfedd0b786b000001
| null |
What is the trade name of sildenafil?
|
{
"answer_start": [
0
],
"text": [
"Viagra"
]
}
|
5e499e266d0a27794100000c
| null |
How are Arboviruses transmitted?
|
{
"answer_start": [
0
],
"text": [
"By arthropods"
]
}
|
58f4b85f70f9fc6f0f000015
| null |
What is the function of the transcriptional co-activator p300?
|
{
"answer_start": [
0
],
"text": [
"histone acetyltransferase"
]
}
|
5c990241ecadf2e73f00002d
| null |
Which molecular does daratumumab target?
|
{
"answer_start": [
0
],
"text": [
"CD38"
]
}
|
5c6545bae842deac6700001d
| null |
Which genes belong to the AUX/IAA family of transcription repressors in plants?
|
{
"answer_start": [
0,
0,
0,
0,
0,
0
],
"text": [
"IAA6",
"IAA9",
"IAA4",
"SCIFTR1",
"SHY2/IAA3",
"BDL/IAA12"
]
}
|
5a86c938faa1ab7d2e000034
| null |
What is the most common monogenic cause of common variable immunodeficiency (CVID) in Europeans?
|
{
"answer_start": [
0
],
"text": [
"Heterozygous loss-of-function variants in NFKB1"
]
}
|
5c629937e842deac67000008
| null |
What organism causes hepatic capillariasis?
|
{
"answer_start": [
0
],
"text": [
"Capillaria hepatica"
]
}
|
5c571dd307647bbc4b000016
| null |
What is the inheritance pattern of Hunter disease or mucopolysaccharidosis II?
|
{
"answer_start": [
0
],
"text": [
"X- linked recessive"
]
}
|
5344155faeec6fbd07000005
| null |
Which receptor(s) recognize lysosomal hydrolases in trans-Golgi network (TGN)?
|
{
"answer_start": [
0,
0,
0,
0
],
"text": [
"mannose 6-phosphate receptors (MPRs)",
"sortilin",
"lysosomal integral membrane protein (LIMP-2)",
"cation-independent mannose 6-phosphate receptor (CI-MPR)"
]
}
|
554101d0234c5a7c75000002
| null |
What is the function of the protein encoded by the gene STING?
|
{
"answer_start": [
0
],
"text": [
"activation of type I interferons"
]
}
|
5c7aae9dd774d0424000000a
| null |
Which cancer is associated with increased levels of Serum alpha fetoprotein (AFP) ?
|
{
"answer_start": [
0,
0
],
"text": [
"HCC",
"hepatocelluar carcinoma"
]
}
|
5c89623bf9c2ba6b28000005
| null |
Which workflow in Bioconductor has been developed for accessing human RNA-seq samples?
|
{
"answer_start": [
0
],
"text": [
"recount2"
]
}
|
5a6e24a5b750ff445500003c
| null |
What disease is associate with defects in both the KDM6A (lysine specific demethylase 6A) and KMT2D (lysine methyltransferase 2D)
|
{
"answer_start": [
0,
0
],
"text": [
"Kabuki syndrome",
"KS"
]
}
|
601ec2d61cb411341a000062
| null |
List types of cancer where TBC1 domain family member 16 (TBC1D16) is involved
|
{
"answer_start": [
0,
0
],
"text": [
"Epithelial ovarian cancer (EOC)",
"Melanoma"
]
}
|
5e52c1fd6d0a27794100004c
| null |
Is golimumab effective for sarcoidosis?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
5e476b99d14c9f295d000001
| null |
Does RUNX2 inhibit astrocyte differentiation?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
5c8fe71b0101eac87000000b
| null |
List the clinical characteristics of the Smith-Kingsmore syndrome (SKS)
|
{
"answer_start": [
0,
0,
0,
0,
0
],
"text": [
"Intellectual disability",
"macrocephaly/hemi/megalencephaly",
"seizures",
"facial dysmorphology",
"other non-neurological features"
]
}
|
5e51c6036d0a27794100003c
| null |
Which are the Atg8 homologs in human?
|
{
"answer_start": [
0,
0,
0,
0,
0,
0
],
"text": [
"MAP1LC3A",
"MAP1LC3B",
"MAP1LC3C",
"GABARAP",
"GABARAPL1",
"GABARAPL2"
]
}
|
51bdf045047fa84d1d000003
| null |
Is RUNX1T1 associate with obesity?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
622608ea3a8413c653000079
| null |
Is carpal tunnel syndrome a type of nerve entrapment?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
601d73ee1cb411341a00003f
| null |
What protein is recruited by Crumbs to regulate tracheal development?
|
{
"answer_start": [
0
],
"text": [
"moesin (Moe)"
]
}
|
5caa0247ecadf2e73f000055
| null |
Is long QT syndrome a cause for sudden cardiac death in athletes?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
53009f6d2059c6d71c00007e
| null |
Please list the 3 findings in HELLP syndrome.
|
{
"answer_start": [
0,
0,
0
],
"text": [
"hemolytic anemia",
"elevated liver enzymes",
"low platlets"
]
}
|
58bc9a5002b8c60953000008
| null |
Which enzyme is inhibited by Imetelstat?
|
{
"answer_start": [
0
],
"text": [
"telomerase"
]
}
|
56c048acef6e39474100001c
| null |
In which genomic positions is the histone variant macroH2A enriched?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"Repressed regions",
"Inactive X chromosome",
"Centromeres"
]
}
|
533c384dc45e133714000006
| null |
Signaling of which pathways is inhibited by Dupilumab?
|
{
"answer_start": [
0,
0
],
"text": [
"interleukin-4",
"interleukin-13"
]
}
|
5880b2a6c872c95565000004
| null |
List 3 enterotoxins produced by Clostridium difficile.
|
{
"answer_start": [
0,
0,
0
],
"text": [
"binary toxin (CDT",
"Toxin A (TcdA)",
"Toxin B (TcdB)"
]
}
|
5c851a8175a4a5d219000005
| null |
Which protein is mutated in Erythropoietic Protoporphyria?
|
{
"answer_start": [
0
],
"text": [
"FECH gene, ferrochelatase"
]
}
|
5e822615835f4e4777000034
| null |
Which type of cells is affected in Amyotrophic Lateral Sclerosis?
|
{
"answer_start": [
0
],
"text": [
"Motor neurons"
]
}
|
56c8274f5795f9a73e00000d
| null |
Which is the most widely used anti-TNF drug?
|
{
"answer_start": [
0
],
"text": [
"Etanercept"
]
}
|
512d0e635274a5fb07000005
| null |
Which post-translational histone modifications are characteristic of facultative heterochromatin?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"H3K9me3",
"H3K9me2",
"H3K36me3"
]
}
|
56c6dc6f5795f9a73e000007
| null |
Has the protein TIEG1 been associated with apoptosis?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
53386282d6d3ac6a3400005a
| null |
Is paxillin affected by RANKL?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
622dc4b63a8413c6530000a4
| null |
List proteins with RING domain.
|
{
"answer_start": [
0,
0,
0,
0,
0,
0,
0
],
"text": [
"RING1",
"TRIM proteins",
"TRAF6",
"UHRF1",
"MARCH7",
"SINA",
"BRCA1"
]
}
|
5c990afbecadf2e73f000030
| null |
Does the word ovine refers to goats?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
58e186fd6fddd3e83e00000f
| null |
A combination of which two drugs was tested in the IMbrave150 trial?
|
{
"answer_start": [
0,
0
],
"text": [
"atezolizumab",
"bevacizumab"
]
}
|
602346eb1cb411341a000090
| null |
Which master regulator drives liver development?
|
{
"answer_start": [
0,
0
],
"text": [
"HNF4a",
"Hepatocyte nuclear factor 4α"
]
}
|
5fdb2e74a43ad3127800000d
| null |
Which molecule is targeted by a monoclonal antibody Secukinumab?
|
{
"answer_start": [
0
],
"text": [
"interleukin-17A"
]
}
|
54e0d7471388e8454a000015
| null |
Which peak calling algorithm employs mixture model clustering under the hood?
|
{
"answer_start": [
0
],
"text": [
"JAMM"
]
}
|
587f760792a5b8ad44000005
| null |
Are EDNRB mutations involved in the development of Hirschsprung disease?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
551910c5622b194345000007
| null |
Is the protein lefty an inhibitor of nodal?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
58a93877ee23e0236b000001
| null |
What are the current treatments for generalised anxiety disorder in teenagers?
|
{
"answer_start": [
0,
0
],
"text": [
"Cognitive-behavioral treatment (CBT)",
"Sertraline"
]
}
|
515db20e298dcd4e51000014
| null |
Is traditional Chinese medicine associated with a decreased risk of heart failure in breast cancer patients receiving doxorubicin treatment?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5e57fa23b761aafe09000008
| null |
What is plantar fasciitis
|
{
"answer_start": [
0
],
"text": [
"heel pain"
]
}
|
58bc8e7a02b8c60953000007
| null |
The small molecule SEA0400 is an inhibitor of which ion antiporter/exchanger?
|
{
"answer_start": [
0,
0
],
"text": [
"Na(+)/Ca(2+) exchanger",
"NCX"
]
}
|
5506c3e38e1671127b00000a
| null |
What are the side effects of deflazacort in DMD patients?
|
{
"answer_start": [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
],
"text": [
"growth failure",
"weight gain",
"facial fullness",
"blood pressure",
"bone health",
"cataracts",
"gastrointestinal symptoms",
"behavioral",
"hypertrichosis",
"need for medical intervention"
]
}
|
5a7727f39e632bc06600000d
| null |
Is MEDI2228 a bispecific antibody?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
62121c583a8413c653000016
| null |
List types of cancer where Long intergenic nonprotein coding RNA p53-induced transcript (LINC-PINT) is involved
|
{
"answer_start": [
0,
0,
0
],
"text": [
"Glioblastoma",
"Breast cancer",
"Pancreatic cancer"
]
}
|
5e493bc06d0a277941000003
| null |
Does administration of triiodothyronine improve outcome following coronary artery bypass grafting?
|
{
"answer_start": [
0,
0
],
"text": [
"no"
]
}
|
532673c4d6d3ac6a34000009
| null |
Is avelumab effective for bladder cancer?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5c72ba807c78d69471000076
| null |
Do Afamin bind Vitamin E?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
622baf3f3a8413c653000099
| null |
Which genes are more frequently affected by somatic mutations in Chronic Lymphocytic Leukemia
|
{
"answer_start": [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
],
"text": [
"TP53",
"ATM",
"NOTCH1",
"XPO1",
"MYD88",
"KLHL6",
"SF3B1",
"ZMYM3",
"MAPK1",
"FBXW7",
"DDX3X"
]
}
|
5171a1498ed59a060a000012
| null |
Is Apremilast effective for Behcet’s syndrome?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
5a7340962dc08e987e000017
| null |
Which receptor is inhibited by Tivozanib?
|
{
"answer_start": [
0
],
"text": [
"vascular endothelial growth factor receptors"
]
}
|
5e2f0afcfbd6abf43b000028
| null |
List sirtuin inhibitors.
|
{
"answer_start": [
0,
0,
0,
0
],
"text": [
"Sirtinol",
"nicotinamide (NAM)",
"LC-0296",
"BZD9L1"
]
}
|
5c8d00980101eac870000006
| null |
Does molindone affect body weight?
|
{
"answer_start": [
0,
0,
0
],
"text": [
"yes"
]
}
|
52cae04c03868f1b06000024
| null |
Which kinases are inhibited by Pyrotinib?
|
{
"answer_start": [
0,
0
],
"text": [
"EGFR",
"HER2"
]
}
|
5e44baaa48dab47f2600001a
| null |
Which is the subcellular localization of the protein angiogenin?
|
{
"answer_start": [
0
],
"text": [
"Both nucleolar and cytoplasmic"
]
}
|
54d7a1047035c08008000002
| null |
Herpes viruses have what type of genome?
|
{
"answer_start": [
0
],
"text": [
"double stranded DNA"
]
}
|
601f105e1cb411341a000071
| null |
End of preview. Expand
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