Datasets:

allenai
/

ms2_dense_oracle

review_id stringlengths 7 8	pmid sequence	title sequence	abstract sequence	target stringlengths 12 3.68k	background stringlengths 3 5.35k
30760312	[ "22776744", "23912836", "22922316", "12821234", "20175775", "23996433", "25271670", "3493740", "20585012", "29167228", "25529339", "16793845", "16697324", "16053970", "6274653" ]	[ "Improved Cell Survival and Paracrine Capacity of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells Promote Therapeutic Potential for Pulmonary Arterial Hypertension", "Double-blind, placebo-controlled clinical trial with a rho-kinase inhibitor in pulmonary arterial hypertension.", "Mesenchymal stem cell...	[ "Although transplantation of adult bone marrow mesenchymal stem cells ( BM-MSCs ) holds promise in the treatment for pulmonary arterial hypertension ( PAH ) , the poor survival and differentiation potential of adult BM-MSCs have limited their therapeutic efficiency . Here , we compared the therapeutic efficacy of h...	Conclusions SC therapy is effective for PAH in pre clinical studies . These results may help to st and ardise pre clinical animal studies and provide a theoretical basis for clinical trial design in the future .	Background Despite significant progress in drug treatment , the prognosis of patients with advanced pulmonary arterial hypertension ( PAH ) remains extremely poor . Many pre clinical studies have reported the efficacy of stem cell ( SC ) therapy for PAH ; however , this approach remains controversial . The aim of this systematic review and meta- analysis is to assess the potential efficacy of SC therapy for PAH .
19588356	[ "10869264", "18448495", "23984728", "11907289", "15358690" ]	[ "Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure.", "A randomised, controlled trial of bosentan in severe COPD", "Macitentan and morbidity and mortality in pulmonary arterial hypertension.", "Bosentan therapy for pulmonary arterial hypertensi...	[ "BACKGROUND Elevated plasma endothelin-1 ( ET-1 ) levels in patients with chronic heart failure correlate with pulmonary artery pressures and pulmonary vascular resistance . ET(A ) receptors on vascular smooth muscle cells mediate pulmonary vascular contraction and hypertrophy . We determined the acute hemodynamic ...	There was a trend for endothelin receptor antagonists to reduce mortality ( OR 0.48 ; 95 % CI 0.21 to 1.09 ) , and limited data suggest that endothelin receptor antagonists improve Borg dyspnoea score and cardiopulmonary haemodynamics in symptomatic patients . Hepatic toxicity was not common , and endothelin receptor antagonists were well tolerated in this population . Endothelin receptor antagonists can increase exercise capacity , improve WHO/NYHA functional class , prevent WHO/NYHA functional class deterioration , reduce dyspnoea and improve cardiopulmonary haemodynamic variables in patients with pulmonary arterial hypertension with WHO/NYHA functional class II and III . However , there was only a trend towards endothelin receptor antagonists reducing mortality in patients with pulmonary arterial hypertension . Efficacy data are strongest in those with idiopathic pulmonary hypertension	BACKGROUND Pulmonary arterial hypertension is a devastating disease , which leads to right heart failure and premature death . Recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension . OBJECTIVES To evaluate the efficacy of endothelin receptor antagonists in pulmonary arterial hypertension .
23893797	[ "22494866", "28100342", "17307412", "22122887", "16084157", "5954842", "21880651", "22319064", "20118154", "3305080" ]	[ "Postconditioning during coronary angioplasty in acute myocardial infarction: the POST-AMI trial.", "[The effect on myocardial perfusion and clinical outcome of intracoronary nicorandil injection prior to percutaneous coronary intervention in ST-segment elevation myocardial infarction].", "Early abciximab admin...	[ "BACKGROUND Postconditioning ( PC ) has been suggested to reduce myocardial damage during primary percutaneous coronary intervention ( PPCI ) , nevertheless clinical experience is limited . We aim ed to explore the cardioprotective effect of PC using cardiac magnetic resonance ( CMR ) in ST-elevation myocardial inf...	This present meta- analysis suggests that statin pretreatment might be effective in improving myocardial perfusion in STEMI patients	BACKGROUND To achieve sufficient myocardial perfusion in ST-segment elevation myocardial infa rct ion ( STEMI ) patients receiving primary percutaneous coronary intervention ( PPCI ) , many adjunctive therapies have been proposed . Previous trials have reported variances in myocardial perfusion improvement for statin pretreatment , which made it inconvincible to confirm the beneficial effects of statins . Therefore , we performed a systematic review and meta- analysis to determine whether statin pretreatment was effective in improving myocardial perfusion . HYPOTHESIS Statin pretreatment could improve myocardial perfusion in STEMI patients undergoing PPCI .
27167891	[ "18719977", "18236304", "25957438", "23674839", "15804687", "21218733", "18713509", "22140149", "21575309", "18713508" ]	[ "Prevalence of and Associations with Waterpipe Tobacco Smoking among U.S. University Students", "Waterpipe tobacco smoking: knowledge, attitudes, beliefs, and behavior in two U.S. samples.", "Waterpipe Tobacco Smoking Prevalence and Correlates in 25 Eastern Mediterranean and Eastern European Countries: Cross-Se...	[ "Background Although waterpipe tobacco smoking seems to be increasing on U.S. university campuses , these data have come from convenience sample s. Purpose We aim ed to determine the prevalence of and associations with waterpipe tobacco smoking among a r and om sample of students . Methods We surveyed a r and om sa...	In conclusion , there is a lack of evidence of effectiveness for most waterpipe interventions .	Waterpipe tobacco smoking is growing in popularity despite adverse health effects among users . We systematic ally review ed the literature , search ing MEDLINE , EMBASE and Web of Science , for interventions targeting prevention and cessation of waterpipe tobacco smoking .
28753768	[ "22706696", "5425353", "19819762", "4570513", "26814279" ]	[ "How do doctors refer to patient-reported outcome measures (PROMS) in oncology consultations?", "Sexual Therapy for Women with Multiple Sclerosis and Its Impact on Quality of Life", "Sex life and sexual function in men and women before and after total disc replacement compared with posterior lumbar fusion.", ...	[ "Purpose We conducted a secondary qualitative analysis of consultations between oncologists and their patients to explore how patient-reported outcome measures ( PROMs ) data were referred to in the process of ( 1 ) eliciting and exploring patients ’ concerns ; ( 2 ) making decisions about supportive treatment and...	Several PROMs have been identified to evaluate sexual function in neurologic patients . Strong evidence was found only for the Multiple Sclerosis Intimacy and Sexuality Question naire-15 and Multiple Sclerosis Intimacy and Sexuality Question naire-19 for patients with MS , although evidence was lacking for certain measurement properties as well .	CONTEXT Impaired sexual function has a significant effect on quality of life . Various patient-reported outcome measures ( PROMs ) are available to evaluate sexual function . The quality of the PROMs to be used for neurologic patients remains unknown . OBJECTIVE To systematic ally review which vali date d PROMs are available to evaluate sexual function in neurologic patients and to critically assess the quality of the validation studies and measurement properties for each identified PROM .
24417824	[ "28059013", "10205319", "12631049", "8526579", "19142085", "24634929", "3127999", "24068549", "22683955", "11254464", "3442968", "14760661", "15979768", "10459075", "23757474", "17541069", "19399583", "19363695" ]	[ "A Carbohydrate-Rich Beverage Prior to Surgery Prevents Surgery-Induced Immunodepression: A Randomized, Controlled, Clinical Trial.", "Preoperative oral carbohydrate administration reduces postoperative insulin resistance.", "Effects of preoperative oral carbohydrates and peptides on postoperative endocrine res...	[ "BACKGROUND Fasting before surgery is still common care in a lot of western hospitals . Overnight fasting can induce postoperative insulin resistance . Insulin resistance has been shown to be related to infectious morbidity . It was shown that postoperative insulin resistance can be attenuated by preoperative intak...	Preoperative carbohydrate drinks significantly improved insulin resistance and indices of patient comfort following surgery , especially hunger , thirst , malaise , anxiety and nausea . No definite conclusions could be made regarding preservation of muscle mass . Following ingestion of carbohydrate drinks , no adverse events such as apparent or proven aspiration during or after surgery were reported . Administration of oral carbohydrate drinks before surgery is probably safe and may have a positive influence on a wide range of perioperative markers of clinical outcome .	INTRODUCTION Surgical stress in the presence of fasting worsens the catabolic state , causes insulin resistance and may delay recovery . Carbohydrate rich drinks given preoperatively may ameliorate these deleterious effects . A systematic review was undertaken to analyse the effect of preoperative carbohydrate loading on insulin resistance , gastric emptying , gastric acidity , patient wellbeing , immunity and nutrition following surgery .
28416626	[ "11692018", "25082804", "23920426", "4501739", "19066101" ]	[ "Management and Prognostic Features of Intracerebral Hemorrhage During Anticoagulant Therapy: A Swedish Multicenter Study", "Variation in Restarting Antithrombotic Drugs at Hospital Discharge After Intracerebral Hemorrhage", "Long-Term Outcome after Anticoagulation-Associated Intracerebral Haemorrhage with or w...	[ "Background and Purpose — Patients treated with oral anticoagulants ( ACs ) have an increased risk of intracerebral hemorrhage ( ICH ) , which is more often fatal than spontaneous ICH . Options to reverse the AC effect include intravenous administration of vitamin K , plasma , and coagulation factor concentrate . ...	Conclusions — In observational studies , reinstitution of anticoagulation after ICH was associated with a lower risk of thromboembolic complications and a similar risk of ICH recurrence .	Background and Purpose — The safety and efficacy of restarting anticoagulation therapy after intracranial hemorrhage ( ICH ) remain unclear . We performed a systematic review and meta- analysis to summarize the associations of anticoagulation resumption with the subsequent risk of ICH recurrence and thromboembolism .
25767129	["24030388","22048460","27116918","21830838","21295286","23536105","22697191","22888309","21810630",(...TRUNCATED)	["Varenicline, smoking cessation, and neuropsychiatric adverse events.","Adjunctive Varenicline Trea(...TRUNCATED)	["OBJECTIVE In 2009 , the U.S. Food and Drug Administration issued a black box warning for varenicli(...TRUNCATED)	"This meta- analysis found no evidence of an increased risk of suicide or attempted suicide , suicid(...TRUNCATED)	"OBJECTIVE To determine the risk of neuropsychiatric adverse events associated with use of varenicli(...TRUNCATED)
26949760	["15202752","26086947","11951800","15732546","25010879","20608298","19544814","26428908","8803392","(...TRUNCATED)	["Clinical performance of large, all-ceramic CAD/CAM-generated restorations after three years: a pil(...TRUNCATED)	["BACKGROUND Adhesively luted all-ceramic restorations preserve and stabilize weakened tooth structu(...TRUNCATED)	"Overall , the 5-year complication rates were low .\nThe most frequent complications were secondary (...TRUNCATED)	"OBJECTIVE The purpose of this systematic review was to compare the survival and complication rates (...TRUNCATED)
21474812	["12411652","26121986","15618441","17060137","4673522","24153026","9684063","12735531","15753416","1(...TRUNCATED)	["Trunk Control as an Early Predictor of Comprehensive Activities of Daily Living Function in Stroke(...TRUNCATED)	["Background and Purpose — Prediction of activities of daily living ( ADL ) functions at an early (...TRUNCATED)	"Because of insufficient method ological quality of most prognostic studies , the predictive value o(...TRUNCATED)	"BACKGROUND AND PURPOSE Knowledge about robust and unbiased factors that predict outcome of activiti(...TRUNCATED)

End of preview. Expand in Data Studio

YAML Metadata Warning: The task_categories "text2text-generation" is not in the official list: text-classification, token-classification, table-question-answering, question-answering, zero-shot-classification, translation, summarization, feature-extraction, text-generation, fill-mask, sentence-similarity, text-to-speech, text-to-audio, automatic-speech-recognition, audio-to-audio, audio-classification, audio-text-to-text, voice-activity-detection, depth-estimation, image-classification, object-detection, image-segmentation, text-to-image, image-to-text, image-to-image, image-to-video, unconditional-image-generation, video-classification, reinforcement-learning, robotics, tabular-classification, tabular-regression, tabular-to-text, table-to-text, multiple-choice, text-ranking, text-retrieval, time-series-forecasting, text-to-video, image-text-to-text, image-text-to-image, image-text-to-video, visual-question-answering, document-question-answering, zero-shot-image-classification, graph-ml, mask-generation, zero-shot-object-detection, text-to-3d, image-to-3d, image-feature-extraction, video-text-to-text, keypoint-detection, visual-document-retrieval, any-to-any, video-to-video, other

This is a copy of the MS^2 dataset, except the input source documents of the train, validation, and test splits have been replaced by a dense retriever.

query: The background field of each example
corpus: The union of all documents in the train, validation and test splits. A document is the concatenation of the title and abstract.
retriever: facebook/contriever-msmarco via PyTerrier with default settings
top-k strategy: "oracle", i.e. the number of documents retrieved, k, is set as the original number of input documents for each example

Retrieval results on the validation set:

Recall@100	Rprec	Precision@k	Recall@k
0.4764	0.2395	0.2395	0.2395

Retrieval results on the validation set:

Recall@100	Rprec	Precision@k	Recall@k
0.4364	0.2125	0.2125	0.2125

Retrieval results on the test set:

Recall@100	Rprec	Precision@k	Recall@k
0.4481	0.2224	0.2224	0.2224

Downloads last month: 22

Size of downloaded dataset files:

403 MB

Size of the auto-converted Parquet files:

403 MB

Number of rows:

17,876