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We present an algorithm that can anticipate tax evasion by modeling the co-evolution of tax schemes with auditing policies. Malicious tax non-compliance, or evasion, accounts for billions of lost revenue each year. Unfortunately when tax administrators change the tax laws or auditing procedures to eliminate known fraud... | During the last decades, universal economy has experienced money laundering and its destructive impact on the economy of the countries. Money laundering is the process of converting or transferring an asset in order to conceal its illegal source or assist someone that is involved in such crimes. Criminals generally att... | This paper describes some pioneering work as a joint research project between City University of Hong Kong and Yuan Ze University in Taiwan to adapt language resources and technologies in order to set up a computational framework for the study of the creative language employed in classical Chinese poetry. ::: ::: In pa... |
Abamectin is used as an acaricide and insecticide for fruits, vegetables and ornamental plants, as well as a parasiticide for animals. One of the major problems of applying pesticides to crops is the likelihood of contaminating aquatic ecosystems by drift or runoff. Therefore, toxicity tests in the laboratory are impor... | Avermectins (AVMs) are used worldwide in agriculture and veterinary medicine. Residues of avermectin drugs, causing toxicological effects on non-target organisms, have raised great concern. The aim of this study was to investigate the effects of AVM on the expression levels of alpha synuclein (α-Syn) and proteasomal ac... | Abstract. Hydrogen isotope ratios of biomarkers have been shown to reflect water isotope ratios, and in some cases correlate significantly with salinity. The δ2H-salinity relationship is best studied for long-chain alkenones, biomarkers for haptophyte algae, and is known to be influenced by a number of different enviro... |
Radiotherapy for head and neck tumors often results in persistent loss of function in salivary glands. Patients suffering from impaired salivary function frequently terminate treatment prematurely because of reduced quality of life caused by malnutrition and other debilitating side-effects. It has been previously shown... | ObjectivesThis study investigated the expression of ΔNp63α in carcinoma cell lines of the upper aerodigestive tract and their potential influence on radioresistance using a small interfering RNA (siRNA) knockdown approach.Materials and methodsFour carcinoma cell lines were investigated for the expression of the ΔNp63 i... | Few studies address food preference of geese on agricultural land (utilization related to availability) and only a handful so for the breeding season. We studied Greylag geese Anser anser during the breeding season in an intensively farmed area in southern Sweden. Few of 22 available field types were truly preferred. P... |
Partly released, relaxed and wrinkled InGaAs membranes are used as virtual substrates for overgrowth with InAs. Such samples exhibit different lattice parameters for the unreleased epitaxial parts, the released flat, back-bond areas and the released wrinkled areas. A large InAs migration towards the released membrane i... | By using density functional theory (DFT) calculations of the potential energy surface in conjunction with the analytical solution of the master equation for the time evolution of the adatom site distribution, we study the diffusion properties of an isolated In adatom on InxGa1−xAs wetting layers (WL) deposited on the G... | Background Dental biomechanics based on finite element (FE) analysis is attracting enormous interest in dentistry, biology, anthropology and palaeontology. Nonetheless, several shortcomings in FE modeling exist, mainly due to unrealistic loading conditions. In this contribution we used kinematics information recorded i... |
This paper presents an ongoing research aimed to build the first corpus, 5 million words, for Mongolian language by focusing on annotating and tagging corpus texts according to TEI XML (McQueen, 2004) format. Also, a tool, MCBuilder, which provides support for flexibly and manually annotating and manipulating the corpu... | This paper presents a first attempt to develop Mongolian speech corpus that designed for data-driven speech synthesis in Mongolia. The aim of the speech corpus is to develop a high-quality Mongolian TTS for blinds to use with screen reader. The speech corpus contains nearly 6 hours of Mongolian phones. It well provides... | Motivated by the low-jitter requirements of streaming multi-media traffic, we focus on the development of scheduling strategies under fading conditions that not only maximize throughput performance but also provide regular inter-service times to users. Since the service regularity of the traffic is related to the highe... |
This work is motivated by the present needs to increase tranmission capacity of power systems operating far from conditions for which they were originally designed, without having to endanger their integrity when an unexpected fault occurs. Most of the theoretical work related to this problem has beenseparated into loa... | In order to provide more reliable state estimation addressing the problem of the bad data (BD) in the Phasor Measurement Unit (PMU)-based power systems synchronization, the paper focuses on developing a novel nonlinear estimation framework to track the voltage magnitude, phase angle, and frequency of the utility power ... | Parkinson’s disease (PD) and atypical Parkinsonian syndromes (aPS) belong to the most common neurologic illnesses. Diagnosis and differential diagnosis of these syndromes is primarily based on well-defined clinical criteria, however, may be difficult in early and particular preclinical/premotor stages. Molecular imagin... |
Using bomb calorimetry and Knudsen effusion methods the enthalpic characteristics in condensed state of ethyl-2-cyano-3-(furan-2-yl) prop-2-enoate derivatives were experimentally determined. The values of the enthalpies of formation in the gas state of investigated esters were calculated taking into account the values ... | The Merck Index is a one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs. Each monograph in this authoritative reference source is a concise description of a single substance or a small group of closely related compounds. Compounds included: * human and veterinary drugs... | Rats were administered various IP doses of the high-affinity dopamine (DA) reuptake inhibitor 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-[3-phenylpropyl]piperazine (GBR12909). The caudate nuclei were removed 60 min after drug administration and stored at -70 degrees C. Striatal membranes were prepared later. The results... |
SummaryX-ray diffraction, infrared absorption spectroscopy, and chemical investigation have been carried out on deproteinated samples of turkey leg tendon at different degrees of calcification. The inorganic phase consists of poorly crystalline B carbonated apatite. On increasing calcification, the apatite crystal size... | X-ray diffraction, i.r. absorption, and chemical analyses have been carried out on the mineral deposits of calcified human mitral valves and glutaraldehyde-preserved porcine aortic grafts. The mineral deposits isolated from highly calcified mitral valves and porcine aortic grafts are constituted of type B-carbonate apa... | Organic nonvolatile photomemory devices have drawn considerable attention in the field of optical computing. However, most organic nonvolatile photomemory devices use a charge-trap-type architecture that is complex and difficult to miniaturize. This paper proposes a nonvolatile polyimide (PI) resistive photomemory devi... |
In the undirected unweighted minimum size k-spanner problem we are given a graph with edges of cost and length 1, and a number k. The goal is to find a minimum size E′ and a graph G′(V,E′) so that for every u, v ∈ V : distG(u, v) distG′(u, v) ≤ k. In [2], a conditional hardness was given to the problem, based on the co... | A set of vertices in a graph is a dominating set if every vertex outside the set has a neighbor in the set. The domatic number problem is that of partitioning the vertices of a graph into the maximum number of disjoint dominating sets. Let n denote the number of vertices, $\delta$ the minimum degree, and $\Delta$ the m... | Exploits the close relationship between circular arc graphs and interval graphs to design efficient approximation algorithms for NP-hard optimization problems on circular arc graphs. The problems considered are maximum domatic partition and online minimum vertex coloring. We present a heuristic for the domatic partitio... |
Distances between mass functions are instrumental tools in evidence theory, yet it is not always clear in which situation a particular distance should be used. Indeed, while the mathematical properties of distances have been well studied, how to interpret them is still a largely open issue. As a step towards answering ... | Abstract We prove that intersections and unions of independent random sets in finite spaces achieve a form of Lipschitz continuity. More precisely, given the distribution of a random set Ξ, the function mapping any random set distribution to the distribution of its intersection (under independence assumption) with Ξ is... | We want to show the difference between the degrees of possibilities (or necessities) and the degrees of belief (or plausibility). The overall principle is that the degrees of possibilities and necessities are the extensions of the modal concept of possibility and necessity whereas degrees of belief and plausibility are... |
Intermittent demand is characterized by occasional demand arrivals interspersed by time intervals during which no demand occurs. These demand patterns pose considerable difficulties in terms of forecasting and stock control due to their compound nature, which implies variability both in terms of demand arrivals and dem... | Although intermittent demand items dominate service and repair parts inventories in many industries, research in forecasting such items has been limited. A critical research question is whether one should make point forecasts of the mean and variance of intermittent demand with a simple parametric method such as simple... | Applies time‐series forecasting, a traditional operations analysis methodology, to develop a forecasting procedure and ordering policy for a natural‐gas customer of Columbia Gas of Ohio, USA. Evaluates six time‐series methods and four operating policies against four commonly used measures of error and the cost conseque... |
Perceptual image hash has been widely investigated in an attempt to solve the problems of image content authentication and content-based image retrieval. In this paper, we combine statistical analysis methods and visual perception theory to develop a real perceptual image hash method for content authentication. To achi... | The block-based analysis for tamper localization is a prevailing mechanism in hash-based forgery detection algorithm. One of the main problems with a block-based analysis is its rough localization stemming from the demand to use relatively large blocks to reduce hash length. While decreasing the block size can improve ... | Photo aesthetic quality evaluation is a fundamental yet under addressed task in computer vision and image processing fields. Conventional approaches are frustrated by the following two drawbacks. First, both the local and global spatial arrangements of image regions play an important role in photo aesthetics. However, ... |
Based on original data (450 samples from 115 streams of European Russian middle latitudes—from Pskov to Kostroma regions), an attempt is made to describe the diversity of rheophilic communities inhabiting stream bottoms and macrophytes. A total of 39 community types are identified by the Braun-Blanquet method. Their ta... | The fauna and diversity of macrozoobenthos communities in watercourses of the Khibiny tundras, the surrounding plains, and the Kandalaksha Coast of the White Sea (Murmansk oblast) are described from materials collected by the authors. A checklist of 110 recorded taxa is given, with larvae of Diptera, Trichoptera, Ephem... | SUMMARY. 1. Invertebrates and fish were surveyed during October 1976 in thirty-four stony riffle stream sites in Ashdown Forest, Sussex.
2. A variety of physicochemical factors were also measured in an attempt to assess the importance of each in determining the distribution of species and the structure of commun... |
Immunization with neurally derived peptides (INDP) boosts the action of an autoreactive immune response that has been shown to induce neuroprotection in several neurodegenerative diseases, especially after spinal cord (SC) injury. This strategy provides an environment that promotes neuronal survival and tissue preserva... | Glaucoma is a neurodegenerative disease with an estimated prevalence of 60 million people, and the most common cause of irreversible blindness worldwide. The mainstay of treatment has been aimed at lowering intraocular pressure, currently the only modifiable risk factor. Unfortunately, despite adequate pressure control... | The confinement of liposomes and Chinese hamster ovary (CHO) cells by infrared (IR) optical tweezers is shown to result in sample heating and temperature increases by several degrees centigrade, as measured by a noninvasive, spatially resolved fluorescence detection technique. For micron-sized spherical liposome vesicl... |
We consider different methods of calculating the (fractional) fermion number of solitons based on the heat kernel expansion. We derive a formula for the localized $$\eta $$η function that provides a more systematic version of the derivative expansion for spectral asymmetry and compute the fermion number in a multi flav... | We study a fermion field coupled to a scalar via a Yukawa term. The scalar field is the $\phi^4$ model with an impurity that preserves half of the BPS property. We analyze the spectrum of the defects of the model and collisions between them both close to the BPS regime and not. As the fermion binds to these defects, it... | The physical importance of inverse problems in quantum scattering theory is clear since all the information we can obtain on nuclear, particle, and subparticle physics is gathered from scattering experiments. Exact and approximate methods of investigating scattering theory, inverse radial problems at fixed energy, inve... |
This paper focuses on how terms of second order λ-calculus, which may take types as inputs, depend on types. These terms are generally understood to have an “essentially” constant meaning, in all models, on input types. We show how the proof theory of second order λ-calculus suggests a clear syntactic description of th... | Contemporary user interface development systems greatly simplify creation of traditional dialogueuser interface made of buttons or menus, but they do not support the construction and manipulation of application-specific graphical objects. This article describes Rollit, adomain-specific , interactive, application builde... | Rockit is a system for the inference of graphical constraints, embedded within a graphical editor as part of larger project on applications development. The graphical editor allows the application designer to draw application-domain-specific objects and define constraints among them. On the basis of direct manipulation... |
This paper presents a vision based sign language gesture recognition framework that can assist people with impaired hearing and speech with their social interaction and interactive communications. Utilizing a low-cost sensor, such as Microsoft Kinect combined with advanced machine learning analysis, it aims to ease the... | In this paper, we develop a vision-based system that employs a combined RGB and depth descriptor to classify hand gestures. The method is studied for a human-machine interface application in the car. Two interconnected modules are employed: one that detects a hand in the region of interaction and performs user classifi... | Species of lactic ::: acid bacteria (LAB) represent as potential microorganisms and have been widely ::: applied in food fermentation worldwide. Milk fermentation process has been ::: relied on the activity of LAB, where transformation ::: of milk to good quality of fermented milk products made possible. The presence o... |
We are building TelegraphCQ, a system to process continuous queries over data streams. Although we had implemented some parts of this technology in earlier Java-based prototypes, our experiences were not positive. As a result, we decided to use PostgreSQL, an open source RDBMS as a starting point for our new implementa... | Scientific experiments produce large volumes of data represented as complex objects that describe independent events such as particle collisions. Scientific analyses can be expressed as queries selecting objects that satisfy complex local conditions over properties of each object. The conditions include joins, aggregat... | In the current study, the authors determined whether adhering to molecular monitoring guidelines in patients with chronic myeloid leukemia (CML) is associated with major molecular response (MMR) and assessed barriers to adherent monitoring. |
Abstract This paper suggests a novel diagnosis scheme for detection, isolation and estimation of faults affecting satellite reaction wheels. Both spin rate measurements and actuation torque defects are dealt with. The proposed system consists of a fault detection and isolation module composed by a bank of residual filt... | Abstract This paper presents a novel scheme for diagnosis of faults affecting the sensors measuring the satellite attitude, body angular velocity and flywheel spin rates as well as defects related to the control torques provided by satellite reaction wheels. A nonlinear geometric design is used to avoid that aerodynami... | An alternative characterization is given of the class of self-bounded controlled invariant subspaces that was introduced by Basile and Marro in Ref. 1. We also prove a result that was stated as a conjecture in the cited paper. |
This paper analyses challenges, and provides a model and a framework for mining Arabic tweets to measure customer satisfaction toward telecom companies in Saudi Arabia, to predict the ratio of customer churn and overcome the specific challenges with the semantic sentiment analysis of Arabic text. | Twitter sentiment analysis offers organizations ability to monitor public feeling towards the products and events related to them in real time. The first step of the sentiment analysis is the text pre-processing of Twitter data. Most existing researches about Twitter sentiment analysis are focused on the extraction of ... | In spite of great efforts that have been made to present systems that support the user's need of the answers from the Holy Quran, the current systems of English translation of Quran still need to do more investigation in order to develop the process of retrieving the accurate verse based on user's question. The Islamic... |
Human herpesvirus-6 (HHV-6) is the causative agent of the common childhood infectious disease, exanthem subitum. After the virus was recently isolated from humans, it was found to be closely related to human cytomegalovirus (CMV), and was thus classified within the beta subgroup of human herpesviruses. HHV-6 possesses ... | Alzheimer’s disease (AD) is the most common form of senile dementia and, due to the worldwide increase of life expectancy, has rapidly become a major medical issue in industrialized countries. The economical toll of AD on public health is enormous, and is estimated to hover actually around US $ 818 billion, representin... | Human B-lymphotropic virus (HBLV), also known as human herpesvirus-6 (HHV-6) was first isolated in 1986 from AIDS patients and patients with other lymphoproliferative disorders. HBLV is distinct from known human herpesviruses, biologically, immunologically and by molecular analysis. HBLV can infect and replicate in fre... |
Feigelson and colleagues have raised some important points concerning the selection of the data sets and the application of meta-analysis to resolve some of the problems associated with determining the relationships between metabolic polymorphisms and susceptibility to various disease conditions. In recent years, many ... | Inter-individual differences in susceptibility to breast cancer are partially mediated through the levels of endogenous and exogenous steroid hormones. The CYP17 gene encodes P450c17alpha, an enzyme that is involved in the metabolism of steroid hormones. Increased endogenous steroid hormone levels have been associated ... | A method for the separation and detection of oligonucleotides utilizing hydrophilic interaction liquid chromatography (HILIC) with inductively coupled plasma mass spectrometry (ICPMS) is described. Polythymidylic acids of various lengths (10, 15, 20 and 30 nucleotides) were separated under gradient HILIC conditions. Se... |
Pluripotent stem cells can differentiate into various lineages but undergo genetic and epigenetic changes during long-term cultivation and, therefore, require regular monitoring. The expression patterns of cancer-testis antigens (CTAs) MAGE-A2, -A3, -A4, -A6, -A8, -B2, and GAGE were examined in undifferentiated human e... | BackgroundThe Cancer/Testis Antigens (CTAs) are a heterogeneous group of proteins whose expression is typically restricted to the testis. However, they are aberrantly expressed in most cancers that have been examined to date. Broadly speaking, the CTAs can be divided into two groups: the CTX antigens that are encoded b... | Allelic mutation on chromosome 19 has previously been reported as a frequent genetic event in human glial tumors. In an effort to localize specific regions of importance on this chromosome better, 13 highly polymorphic genetic markers distributed along the length of chromosome 19 were used for evaluation of loss of het... |
3D-IC is a solution to achieve lower cost and higher performance as the transistor density doubles every 18 months following Moore's law. In recent years, Integrated Fan-Out Wafer-Level Chip-Scale Packaging (InFO WLCSP) is one of the most promising packaging technologies for 3D-IC. In InFO WLCSP, there are some inter-d... | To be “More than Moore's law”, Integrated Fan-Out Wafer-Level Chip-Scale Packaging (InFO WLCSP) is more cost-effective than other 3D-integrated-circuit (3DIC) technologies for consumer mobile, wearable, and “Internet-of-Things” (IoT) markets. To further improve the test quality, yield, and cost of InFO WLCSP by probing... | Distribution system operators are investigating new methods to manage network congestion and avoid overloading. Among these methods is the application of flexibility. This paper will present a field implementation as part of the H2020 Interflex project. Two parallel mechanisms will be implemented: a local flexibility m... |
Magnesium in its ionic form (Mg 2 + ) is essential for many physiological processes, including much of metabolism, enzyme activation and catalysis, photosynthesis development, signal transduction, and protection against hypertension and blood vessel spasm. [ 1 ] Therefore, it has been long recognized that for suitable ... | DNA-functionalized nanoparticle (DfNP) technology, the integration of DNA with nanotechnology, has emerged over recent decades as a promising biofunctionalization tool in the light of biotechnological approaches. The development of DfNPs has exhibited significant potential for several biological and biomedical applicat... | Abstract Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was applied to study source identification by using elemental fingerprint analysis combined with the use of multivariate statistical analysis of gem corundum samples with different colors (red, blue, purple, yellow) from six countries (Ken... |
Therapeutic efficacy of an Indian Ayurvedic medicinal preparation, Ashwagandha [Withania somnifera L. Dunal (Solanceae; root)] was evaluated against experimental aspergillosis in Balb/c mice. Ashwagandha given orally once daily for 7 consecutive days in a dose of 100 mg/kg after intravenous infection of Aspergillus fum... | SUMMARY The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists, and natural-products chemists are combing the Earth for phytochemicals and “leads” which could be developed for treatment of infectious diseases. While ... | As reported previously, antigenically stimulated guinea pig lymphocytes elaborate a soluble factor which activates macrophages in the sense of promoting increased adherence, spreading, phagocytosis, and glucose oxidation through the hexose monophosphate pathway. Further studies on the characteristics and kinetics of th... |
The ground-state electronic order in doped manganites is frequently associated with a lattice modulation, contributing to their many interesting properties. However, measuring the thermal evolution of the lattice superstructure with reciprocal-space probes alone can lead to ambiguous results with competing interpretati... | Collective dynamics often play an important role in determining the stability of ground states for both naturally occurring materials and metamaterials. We studied the temperature dependent dynamics of antiferromagnetically ordered superdomains in a square artificial spin lattice using soft x-ray photon correlation spe... | 3-D printing enables the fabrication of complex architectures at multiple length scales by automating large sequences of additive steps. The increasing sophistication of printers, materials, and generative design promise to make geometric complexity a nonissue in manufacturing; however, this complexity can only be real... |
The formation of the 5,5-dimethyl-1-pyrroline N-oxide (DMPO)/.OH adduct of the spin trap DMPO has been reported to occur through nucleophilic addition of water in the presence of aqueous ferric chloride (K. Makino, T. Hagiwara, A. Hagi, M. Nishi, and A. Murakami, 1990, Biochem. Biophys. Res. Commun. 172, 1073-1080). Du... | 2-Hydroxy-5,5-dimethyl-1-pyrrolidinyloxy (DMPO-OH), which is known to be produced by spin trapping of hydroxyl radicals (.OH) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) and has been a good monitor for detecting .OH in biological systems, has been examined by EPR for its production scheme in the presence of iron ion. ... | Abstract In the present era, environmental pollution are increasing manifolds due to various anthropogenic activities. Organic pollutants are one of the biggest nuisances faced by the present human population. Several measures have been proposed and applied for their abatement. Organic pollutants released from the vari... |
This analysis extends creative design thinking to the macro-level, applying it to the enormous problems and opportunities generated by twenty-first century globalization. Today’s macroproblems and macro-opportunities require creative, interdisciplinary thinking, and collaboration to enable individuals and teams to addr... | In recent decades, empathy research has blossomed into a vibrant and multidisciplinary field of study. The social neuroscience approach to the subject is premised on the idea that studying empathy at multiple levels (biological, cognitive, and social) will lead to a more comprehensive understanding of how other people'... | Is creativity domain-specific? We describe the value of latent class analysis for appraising domain generality, and we report two studies that explore the latent class structure of creative accomplishments (using Carson, Peterson, and Higgins’s Creative Achievement Questionnaire; n = 749) and creative self-descriptions... |
The distributed source inverse problem for Magnetoencephalography (MEG) requires regularisation in order to calculate a stable and accurate solution. Recently there has been interest in source reconstruction via the l1 penalised least squares problem. Although this gives some sparseness the ideal measure for sparsity i... | This paper addresses the problem of identifying the topology of a sparsely connected network of dynamic systems. The goal is to identify the links, the direction of information flow and the transfer function of each dynamic system. The output of each system is affected by the incoming data of the directly connected sys... | In this paper, we present a novel approach to imaging sparse and focal neural current sources from MEG (magnetoencephalography) data. Using the framework of Tikhonov regularization theory, we introduce a new stabilizer that uses the concept of controlled support to incorporate a priori assumptions about the area occupi... |
The objective of this study was to investigate the influence of type of cross-linking method used on the properties of ambroxol hydrochloride microspheres such as encapsulation efficiency, particle size, and drug release. Microspheres were prepared by solvent evaporation technique using chitosan as a matrix-forming age... | The aim of the study was to compare the gelation and drug release characteristics of formulations of pectin with high (31%) and low (9%) degrees of methoxylation over a wide pH range (pH 1.2-5.0). Dilute solutions of pectin (1.5%, w/v) containing complexed calcium ions formed gels in vitro at low pH (pH<2.5) as a conse... | We have measured the optical transmission of quasiperiodic dielectric multilayer stacks of ${\mathrm{SiO}}_{2}$ (A) and ${\mathrm{TiO}}_{2}$ (b) thin films which are ordered according to a Fibonacci sequence ${\mathit{S}}_{\mathit{j}+1}$={${\mathit{S}}_{\mathit{j}\mathrm{\ensuremath{-}}1}$}, with ${\mathit{S}}_{0}$={B}... |
It is not true that mirror self-recognition has nothing to do with self-awareness and, contrary to Suddendorf and Butler's claim [1], that self-recognition is ‘universally acquired in toddlers’, there are failures to find mirror self-recognition in mentally retarded children, adolescents, and adults, as well as in auti... | At its most basic level, the sense of self is built upon awareness of one's body and the face holds special significance as the individual's most important and distinctive physical feature. Multimodal sensory integration is pivotal to experiencing one's own body as a coherent visual “self” representation is formed and ... | A multicomponent-fuel e lm-vaporization model is developed to be used in multidimensional spray and combustion computations. For the gas phase the vaporization rate was evaluated using the turbulent boundary-layer assumption and the Prandtl mixing-length theory. A third-order polynomial was used to model the temperatur... |
Workflow technology has emerged as an appropriate platform for consolidating the distributed information resources of an enterprise, promoting interoperability across cross-platform systems and for providing a global view and understanding of business process models. However, the business processes that workflows repre... | The advantages of today'sprocess management, such as efficiency and quality aspects, are achievedby enforcing detailed models of work processes. But real world processescan be planned only to a limited degree and sometimes demand changing alreadyplanned parts of the process. So additional, unforeseen activities haveto ... | This paper addresses the challenge of fault location in large power networks using a limited number of sensors. It was recently shown that power system faults may be modeled by sparse vectors, and hence, can be located efficiently using sparse recovery techniques. In this paper, we extend this approach and propose a sp... |
Extensive shooting and angling causes, indirectly, fatal lead poisoning of birds. European Union policy on this major source of pollution is inconsistent with its laws regulating other forms of lead in the environment. Only three countries have banned the use of lead shot completely in the European Union, despite avail... | Each year, 1.2 million Spanish hunters and shooters discharge 6,000 t of lead shot, of which 30-50 t are deposited in wetlands of this European country. Waterfowl may accidentally ingest lead pellets in these aquatic habitats and become fatally lead poisoned. It has been estimated that 50,000 birds die from this cause ... | Rice samples consumed by local populations were collected between 1990 and 1995 in 17 areas in the world, mostly from Asia (10 areas), but also from 7 areas outside of Asia. In total, 1528 samples were obtained (about one half from Japan) and were analyzed for lead (Pb) by electrothermal atomic absorption spectrometry.... |
A hybrid fuzzy knowledge-based system with crisp and fuzzy rules as well as numerical methods was developed for multiobjective optimization of power distribution system operations. The development process and knowledge acquisition process for the fuzzy knowledge-based system are described in detail. The fuzzy knowledge... | A knowledge-based system is defined that ensures network radiality during reconfiguration of a power distribution system. Network radiality heuristics identify a pair of switching operations that preserves radiality. A matrix-structured knowledge base with five distinct rule bases is used. Rule base A is used in determ... | Fungi are prone to phenotypic instability, that is, the vegetative phase of these organisms, be they yeasts or molds, undergoes frequent switching between two or more behaviors, often with different morphologies, but also sometime having different physiologies without any obvious morphological outcome. In the context o... |
A model composed of van der Waals-like and hydrogen bonding contributions that simulates the low-temperature anomalous thermodynamics of pure water while exhibiting a second, liquid-liquid critical point [P. H. Poole et al., Phys. Rev. Lett. 73, 1632 (1994)] is extended to dilute solutions of nonionic species. Critical... | Osmotic second virial coefficients in dilute aqueous solutions of small nonpolar solutes are calculated from three different two-component equations of state. The solutes are five noble gases, four diatomics, and six hydrocarbons in the range C1-C4. The equations of state are modified versions of the van der Waals, Red... | When an emulsified 4.8 mol % LiCl-H2O solution was cooled under a pressure of 0.35 or 0.45 GPa and decompressed to 0.1 GPa at 142 K, slightly above its glass transition temperature (approximately 140 K at 0.1 GPa), its volume increased suddenly. This was regarded as an appearance of the low-density amorphous ice in the... |
Rational development of transcranial current stimulation (tCS) requires solving the ‘forward problem’: the computation of the electric field distribution in the head resulting from the application of scalp currents. Derivation of forward models has represented a major effort in brain stimulation research, with model co... | Research in the area of transcranial electrical stimulation (TES) often relies on computational models of current flow in the brain. Models are built on magnetic resonance images (MRI) of the human head to capture detailed individual anatomy. To simulate current flow, MRIs have to be segmented, virtual electrodes have ... | THE FINDINGS that schizophrenics are not psychologically harmed by rapid eye movement (REM) deprivation and that they respond physiologically to REM deprivation in the same way as nonschizophrenics 1 dissuaded us from the prevailing view that REM deprivation is a causal factor in psychosis. As a result, we began to con... |
Purpose The purpose of the present study was to investigate the correlation between the postoperative stability and area of pterygomasseteric sling (PMS). Materials and Methods Forty patients of mandibular prognathism were treated by isolated mandibular setback. Serial lateral cephalograms were collected (preoperativel... | OBJECTIVE
To evaluate the long-term changes of masseter muscle morphology in skeletal Class III patients with facial asymmetry following two-jaw orthognathic surgery (Le Fort I osteotomy + intraoral vertical ramus osteotomy).
MATERIALS AND METHODS
Using computed tomography (CT), a longitudinal study was conducted on ... | PURPOSE
This study was designed to examine skeletal stability after surgical correction of mandibular prognathism using a sagittal split ramus osteotomy (SSRO) and fixation with poly-L-lactic acid (PLLA) screws.
PATIENTS AND METHODS
Twenty patients with Class III malocclusion were treated with bilateral SSRO and mand... |
The Hasse-Weil-Serre bound is improved for low genus curves over finite fields with discriminant from {-3,-4,-7,-8} by studying maximal and minimal curves. | We show that for all finite fields Fq, there exists a curve C over Fq of genus 3 such that the number of rational points on C is within 3 of the Serre–Weil upper or lower bound. For some q, we also obtain improvements on the upper bound for the number of rational points on a genus 3 curve over Fq. | This paper is about efficiently analyzing deadlock and blocking for systems consisting of isomorphic modules instantiated from a template. By refining the template, our approach captures essential interactions among modules and efficiently determine whether a system of an arbitrary number of modules is deadlock free or... |
Dynamic software updating (DSU) enables running programs to be updated with new code and data without interrupting their execution. A number of DSU systems have been designed, but there is still little rigorous understanding of how to use DSU technology so that updates are safe. As a first step in this direction, we in... | Using plugins as a mechanism for extending applications to provide extra functionality is appealing, but current implementations are limited in scope. We have designed a framework to allow the construction of flexible and complex systems from plugin components. In this paper we describe how the use of modelling techniq... | In constructing a general purpose programming language, a key issue is providing a sufficient set of data types and associated operations in a manner that permits both natural problem-oriented notation and efficient implementation. The EL1 language contains a number of features specifically designed to simultaneously s... |
Although the outcome of therapy for leukemia has improved over the years, mainly in younger patients, less than a third of adults with acute myeloid leukemia (AML), for example, are cured by current treatments, a fact stressing the need for new therapeutic approaches. Since leukemias are considered disorders of self-re... | UNLABELLED
Recent technological advances in nanomedicine and nanotechnology in parallel with knowledge accumulated from the clinical translation of disease- and drug-related genomic data have created fertile ground for personalized medicine to emerge as the new direction in diagnosis and drug therapy. To this end, the ... | ABSTRACT The t(8;21)(q22;q22) translocation, which fuses the ETO gene on human chromosome 8 with the AML1 gene on chromosome 21 (AML1-ETO), is one of the most frequent cytogenetic abnormalities associated with acute myelogenous leukemia (AML). It is seen in approximately 12 to 15% of AML cases and is present in about 4... |
Monitoring of latent Mycobacterium tuberculosis infection may prevent disease. We tested an ESAT-6 and CFP-10-specific IFN-γ Elispot assay (RD1-Elispot) on 163 HIV-infected individuals living in a TB-endemic setting. An RD1-Elispot was performed every 3 months for a period of 3–21 months. 62% of RD1-Elispot negative in... | SETTING
South African gold mines.
OBJECTIVE
To determine the prevalence of latent tuberculosis infection (LTBI) and risk factors for a positive tuberculin skin test (TST) among gold miners.
DESIGN
Cross-sectional survey. Human immunodeficiency virus (HIV) status was determined by self-report and medical records. TS... | New tools are needed to match pancreatic cancer patients with effective treatments. Patient-derived organoids offer a high-throughput platform to personalize treatments and discover novel therapies. Currently, methods to evaluate drug response in organoids are limited because they cannot be completed in a clinically re... |
Background Clinical and biomechanical studies have demonstrated the increase in contact pressure and progressive deterioration of the tibiofemoral compartments that occur after partial or complete meniscectomy. Meniscus transplantation has been indicated for the symptomatic postmeniscectomy patient to alleviate symptom... | Background: Meniscal allograft transplantation is a viable option for subtotally meniscectomized and totally meniscectomized symptomatic patients and potentially results in pain relief and increased function. Hypothesis: The use of a single tibial tunnel arthroscopic technique without bone plugs will reduce symptoms (p... | Experience with fresh osteochondral allografting for cartilage defects in the knee now extends two decades. Clinical outcomes and basic scientific investigations have supported the theoretic basis for this procedure. At the University of California, San Diego, our experience has encouraged us to continue to offer this ... |
An innovative numerical method based on an artificial neural network is presented in order to solve an inverse problem associated with the calculation of the Dirichlet eigenvalues of the anisotropic Laplace operator. Using a set of predefined eigenvalues obtained by solving repeatedly the direct problem, a radial basis... | It has been found recently that the multiple reciprocity method (MRM) (Chen and Wong. Engng. Anal. Boundary Elements 1997; 20(1):25–33; Chen. Processings of the Fourth World Congress on Computational Mechanics, Onate E, Idelsohn SR (eds). Argentina, 1998; 106; Chen and Wong. J. Sound Vibration 1998; 217(1): 75–95.) or ... | Casimir operators -- the generators of the center of the enveloping algebra -- are described for simple or close to them ``classical'' finite dimensional Lie superalgebras with nondegenerate symmetric even bilinear form in Sergeev A., The invariant polynomials on simple Lie superalgebras. Represent. Theory 3 (1999), 25... |
Psychosocial stress is associated with chronic disease. We evaluated whether in the general population the number of stressful life events is associated with risk of mortality and whether this association is mediated by behavioral factors and morbidities. We conducted this study in the Hoorn cohort; a population-based ... | Cardiovascular survey methods , Cardiovascular survey methods , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی | Background The equid Hippotherium primigenium, with moderately hypsodont cheek teeth, rapidly dispersed through Eurasia in the early late Miocene. This dispersal of hipparions into the Old World represents a major faunal event during the Neogene. The reasons for this fast dispersal of H. primigenium within Europe are s... |
The contents of many valuable web-accessible databases are only accessible through search interfaces and are hence invisible to traditional web “crawlers.” Recent studies have estimated the size of this “hidden web” to be 500 billion pages, while the size of the “crawlable” web is only an estimated two billion pages. R... | When a query is submitted to a search engine, the search engine returns a dynamically generated result page that contains the number of hits (i.e., the number of matching results) for the query. Hit number is a very useful piece of information in many important applications such as obtaining document frequencies of ter... | The challenge for nanotechnology application in automotive lubrication is the difficulty in dispersing the nanoparticles in lubricating oils. Some factors have a direct influence on the dispersion of particles, such as size and shape, which are controlled by the chosen synthesis method. In addition, the use of covers a... |
Abstract In this study, a model for the estimation of the dynamics of the lower extremities in standing sway from force plate data only is presented. A three-dimensional, five-segment, four-joint model of the human body was used to describe postural standing sway dynamics. Force-plate data of the reactive forces and ce... | Control of standing requires the continuous activity of the leg muscles. In single leg standing the system is less redundant and muscular activity is more intensive. The objective of this study was to examine the effect of force imbalance of the shank muscles, evoked by their selective fatiguing, on postural control in... | A 23 dBm class E power amplifier (PA) has been designed and simulated at 3.7 GHZ using a 130 nm CMOS-SOI technology. The PA is a single stage, single ended cascode formed by a thin oxide transistor as common source device and a laterally diffused MOS (LDMOS) transistor as common gate. Fully integrated high current indu... |
Solid stems provide resistance to the wheat stem sawfly (WSS, Cephus cinctus Nort.) in wheat (Triticum aestivum L.). A major quantitative trait locus, designated Qss.msub-3BL, controls most of the variation for stem solidness. Two alleles that differ for temporal expression of stem solidness have been identified. An al... | Abstract Wheat stem sawfly, Cephus cinctus Norton, is an economically serious pest of cereals grown in North America. Barley cultivars were previously planted as resistant crops in rotations to manage C. cinctus, but due to increasing levels of injury to this crop, this is no longer a valid management tactic in Montana... | For 12 cultivars of wheat grown under a 21°C day/16°C night temperature regime, spikelet number was closely related to grain number, but not to grain yield per ear as individual grain weights differed considerably between cultivars. However, when spikelet number was varied by day length or vernalization treatment, grai... |
Explicitly or implicitly, all the theoretical models examined so far, have a common set of assumptions: perfect competition, the rigid supply of productive factors, absence of intermediate goods, absence of transport costs, certainty, absence of illegal trade (such as smuggling), and so on. These are undoubtedly assump... | This paper addresses the relation between goods trade and international factor mobility in general terms. Conditions for factor price equalization are derived for situations with tradein both goods and factors,as well as Rybczynski and Stolper-Sarnuel Sofl theorems. A weak price versionof the Heckscher-Ohlifl theorem i... | It is well known that the law of comparative advantage breaks down when applied to individual commodities or pairs of commodities in a many-commodity world. This paper shows that the law is nonetheless valid if restated in terms of averages across all commodities. Specifically, a theorem and several corollaries are der... |
In the last three years, there has been a great deal of turbulence in U.S. defense acquisition policy. This has contributed to confusion within the acquisition workforce in terminology, major policy thrusts, and unclear implications of the changes. The new acquisition framework has added complexity, with more phases an... | Preface Part I. An Overview Introduction Part II. Some Images of Organization 2. Mechanization Takes Command: Organizations as Machines Machines, Mechanical Thinking, and the Rise of Bureaucratic Organization The Origins of Mechanistic Organization Classical Management Theory: Designing bureaucratic organizations Scien... | Abstract : In October 2000 the Secretary of Defense announced that a new policy of revolutionary acquisition would become the preferred approach to acquiring defense systems. Implementation of the new policy has been far from automatic. Today - two years after issuance of the evolutionary acquisition policy - the Depar... |
The influence of bonding pressure during low temperature direct metal bond formation between gold studs and electroplated copper joints respectively was evaluated. The findings obtained showed an optimum pressure where bond strength peaks before degrading at further increase in bond pressure. Furthermore, it was found ... | This article discusses thermo-compression bonding (also known as diffusion bonding) of metallic copper and its application in 3-D stacking of ICs. Bonding process is described and characterization results are presented. A survey on recent progress of copper-based wafer bonding, particularly low temperature process, and... | Vesicles and many biological membranes are made of two monolayers of lipid molecules and form closed lipid bilayers. The dynamical behavior of vesicles is very complex and a variety of forms and shapes appear. Lipid bilayers can be considered as a surface fluid and hence the governing equations for the evolution includ... |
Abstract First results are reported from a program for measuring the field-to-field fluctuation level of the cosmic diffuse background by using differences between the two background positions of each deep exposure with the HEXTE instrument on RXTE. With 8 million live seconds accumulated to date a fluctuation level on... | We show that Compton scattering by electrons of the hot intergalactic gas in galaxy clusters should lead to peculiar distortions of the cosmic background X-ray and soft gamma-ray radiation - an increase in its brightness at E 1, the effect allows one to determine how the X-ray background evolved and how it was "gathere... | Using d a ta from th e L e ic e s te r U n iv e rs ity A r ie l V Sky Survey Instrum ent (SSl) th e work re p o rte d in t h i s th e s is e s ta b lis h e s th a t S e y fe r t g a la x ie s form a c la s s o f e x tr a g a la c t ic x -ray so u rc e . The p ro p e r tie s o f S e y fe r t g a la x ie s a re review ed... |
Objective: The objective of this study is to evaluate our methods for management of renal caliceal diverticular stones (CDS). Materials and Methods: We conducted a retrospective study from January 2005 to July 2015 and included patients who were treated for renal CDS. Patients were evaluated for treatment modality, pun... | Introduction. Calyx diverticulum is a rather rare pathology in pediatric practice. In the structure of cystic kidney malformations, it amounts up to 12-15%. In most cases, the disease is asymptomatic. To make a differential diagnostics and to define a technique for surgical treatment, computed tomography or magnetic re... | Stones in calyceal diverticula present an interesting problem, both surgical and metabolic. Authors from the USA used a comprehensive metabolic evaluation of patients with these stones, and found consistent abnormalities. They also found that these could be corrected with selective medical therapy, and this was associa... |
Ontologies evolve continuously throughout their lifecycle to respond to different change requirements. Several problems emanate from ontology evolution: capturing change requirements, change representation, change impact analysis and resolution, change validation, change traceability, change propagation to dependant ar... | A suite of metrics is proposed to assess the quality of an ontology. Drawing upon semiotic theory, the metrics assess the syntactic, semantic, pragmatic, and social aspects of ontology quality. We operationalize the metrics and implement them in a prototype tool called the Ontology Auditor. An initial validation of the... | Rule Engines have been widely used both in industry and academia since they can separate rule knowledge from implementation logic conveniently and flexibly. However, traditional rule engine systems can not deal with big data, because of the limitations of memory and computing capacity of one single computer. Consequent... |
Guadeloupean Parkinsonism has been linked epidemiologically to the consumption of Annonaceae fruits. These were proposed to be etiological agents for sporadic atypical Parkinsonism worldwide, because of their content of neurotoxins such as isoquinolinic alkaloids and Annonaceous acetogenins. The pulp of Annona cherimol... | The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out... | Since memristor was predicted by Chua L O from symmetry arguments and produced at HP laboratory in 2008, it has become one of the most popular research directions in the related fields of automation. In this paper, the origin of the memristor is investigated, the memristor classification and its manufacturing technolog... |
Contaminant composition affects the discharge characteristics of external insulation. This paper studies the intense discharge phenomenon at low relative humidity (77%) in an AC 500 kV substation in Southern China. Due to farming and the soil feature in the sugar cane field around the substation, aluminum phosphate is ... | This paper attempts to address the influence of sugar as a contaminant on outdoor insulation characteristics of insulators in a substation. Strong discharge activity was occurred under relative humidity less than 80% on insulators in a 500 kV substation at south China. A preliminary viewpoint that sugar as a contaminan... | A discussion is presented of the influence of desert contamination on the breakdown voltage characteristics of rod-plane air gaps when subjected to standard lightning impulse voltages of positive and negative polarities. Experimental simulation of desert air pollution was carried out in a chamber where particle paramet... |
A previously unrecognized neuropathy was identified in Bulgarian gypsies, and was designated hereditary motor and sensory neuropathy-Lom (HMSNL) after the town where the initial cases were found. It was subsequently identified in other gypsy communities. The disorder, which is of autosomal recessive inheritance, was ma... | Founder effect and linkage disequilibrium have been successfully exploited to map single gene disorders1, and the study of isolated populations is emerging as a major approach to the investigation of genetically complex diseases2. In the search for genetic isolates ranging from Pacific islands to Middle East deserts, t... | A laboratory investigation consisting of EEG recordings, BAEPs and VEPs evaluation as well as estimation of the facial nerve distal latency was performed in 9 patients who had Charcot Marie Tooth (type HMSN I) disease. 3 patients showed VEP's abnormalities (2 of them had prolonged P100 latency and one had an abnormal i... |
Extraordinary optical transmission (EOT) of both transverse-electric (TE) and transverse-magnetic (TM) polarizations was investigated for sub-wavelength metallic structures by the rigorous coupled-wave analysis, implemented as the Airy-like internal reflection series. Generally, because of the absence of coupled surfac... | A review and analysis is performed of various resonance effects associated with subwavelength one-dimensional (1-D) metal gratings for transverse electric (TE) and transverse magnetic (TM) polarized incident radiation. It is shown that by tuning the structural geometry (especially the groove width) and material composi... | A rigorous method of modeling the performance of metal-semiconductor-metal photodetectors (MSM-PD) that use several electromagnetic resonance (ER) modes and optical modes to enhance performance is presented. These ER and optical modes include surface plasmons, Wood-Rayleigh anomalies and vertical cavity modes. Five mod... |
Studies examining the use of pre‐exposure prophylaxis (PrEP) to prevent HIV transmission among people who inject drugs (PWIDs) have not been adequately summarized. Recently, the Bangkok Tenofovir Study has shown that PrEP may be effective at reducing new HIV infections among this high‐risk group. This randomized contro... | BACKGROUND
Recent trials report the short-term efficacy of tenofovir-based pre-exposure prophylaxis (PrEP) for prevention of human immunodeficiency virus (HIV) infection. PrEP's long-term impact on patient outcomes, population-level transmission, and cost-effectiveness remains unknown.
METHODS
We linked data from rec... | Bacille Calmette-Guérin (BCG) immunotherapy is currently considered the most effective agent in the management of superficial bladder cancer. Prior work suggests that the efficacy of intravesical chemotherapy in preventing tumor recurrence may be greater than previously suggested. This latter finding, therefore, brings... |
Cumulative evidence has proven the safety, feasibility and efficacy of stem cell therapy for cardiomyocyte replacement in heart failure treatment. In contrast to embryonic stem cells, induced pluripotent stem cells (iPS cells) provide a route to the production of patient-specific stem cell lines with no ethical concern... | IntroductionMolecular imaging strives to visualise processes at the molecular and cellular level in vivo. Understanding these processes supports diagnosis and evaluation of therapeutic efficacy on an individual basis and thereby makes personalised medicine possible.Apoptosis and molecular imagingApoptosis is a well-org... | PurposeAcute renal tubular necrosis (ATN), a common cause of acute renal failure, is a dynamic, rapidly evolving clinical condition associated with apoptotic and necrotic tubular cell death. Its early identification is critical, but current detection methods relying upon clinical assessment, such as kidney biopsy and f... |
Recently, formal verification has had success in rigorously checking the correctness of digital designs. We have developed the LEMA tool to provide a methodology for the formal verification of analog/mixed-signal (AMS) circuits. In particular, LEMA utilizes a labeled Petri net (LPN) model to represent AMS circuit behav... | This paper presents two symbolic model checking algorithms for the verification of analog/mixed-signal circuits. The first model checker utilizes binary decision diagrams while the second is a bounded model checker that uses a satisfiability modulo theory solver. Both methods have been implemented, and preliminary resu... | Parametric curves and surfaces are topics usually included in different disciplines, such as computer graphics, geometric modeling, computer-aided design (CAD), computer-aided geometric design (CAGD), etc. These rapidly emerging and extensive fields require students to understand a wide range of methods. In this contex... |
Purpose It is unknown whether there is a benefit to starting androgen deprivation therapy (ADT) prior to rather than concurrently with definitive radiation therapy in men with high-risk prostate cancer. We studied the National Cancer Data Base to determine whether the timing of ADT impacts survival. Methods Men diagnos... | BACKGROUND
The aim of this trial was to compare dose-escalated conformal radiotherapy with control-dose conformal radiotherapy in patients with localised prostate cancer. Preliminary findings reported after 5 years of follow-up showed that escalated-dose conformal radiotherapy improved biochemical progression-free surv... | Abstract One or more new specific antigens are present in “virus-free” polyoma tumors, as demonstrated by their complement fixation reaction with serum from animals carrying transplantable tumors. These antigens cannot be found in normal animal tissues or in tumors induced by other viruses or by methylcholanthrene. Mou... |
Giant Spin Hall One of the primary challenges in the field of spin-electronics, which exploits the electron's spin rather than its charge, is to create strong currents of electrons with polarized spins. One way to do this is to use a ferromagnet as a polarizer, a principle used in magnetic tunnel junctions; however, th... | Brain-inspired computing architectures attempt to mimic the computations performed in the neurons and the synapses in the human brain in order to achieve its efficiency in learning and cognitive tasks. In this work, we demonstrate the mapping of the probabilistic spiking nature of pyramidal neurons in the cortex to the... | Purpose – The purpose of this paper is twofold. First, to propose a new metaphor, student‐as‐aspirant, which captures well the educational role of students, professors, and business schools. Second, to develop the strategic implications of this metaphor for the management of business schools.Design/methodology/approach... |
In this letter, we investigate the bit-error rate (BER) performance of uncoded space-time transmit diversity (STTD) aided interleave division multiple access (IDMA) scheme for down-link (DL) communications. In this contribution, we consider the orthogonal structure based on Alamouti Space-Time code which offers full ra... | In this correspondence, we investigate and study the performance of multi-user transmitter preprocessing (MUTP) aided multi-carrier interleave division multiple access (MC-IDMA) systems in frequency-selective channels under perfect and imperfect channel state information (CSI) at the transmitter. The MUTP considered in... | Herein, we report the microscopic origin of surfactant modified magnetic properties of nearly monodispersed CoFe2O4 nanoparticles (NPs). Surface modification is carried out with four surfactants having π-acceptor/π-donor head group along with different chain-length. Upon functionalization, magnetic NPs show a maximum 6... |
Social media shatters the barrier to communicate anytime anywhere for people of all walks of life. The publicly available, virtually free information in social media poses a new challenge to consumers who have to discern whether a piece of information published in social media is reliable. For example, it can be diffic... | The results of the 2016 Brexit referendum in the U.K. and presidential election in the U.S. surprised pollsters and traditional media alike, and social media is now being blamed in part for creating echo chambers that encouraged the spread of fake news that influenced voters. | Generating humor and quotes are very challenging problems in the field of computational linguistics and are often tackled separately. In this paper, we present a controlled Long Short-Term Memory (LSTM) architecture which is trained with categorical data like jokes and quotes together by passing category as an input al... |
We present a simple and wait-free implementation of a snapshot shared data structure suitable for real-time systems with sporadic tasks. Snapshot mechanisms give the means to a real-time task to read a globally consistent set of variable values while other concurrent tasks are updating them. Such a mechanism can be use... | We present 2V-DBP-SNAP, an algorithm that allows hard real-time tasks in an embedded real-time control system to read a snapshot of a number of data elements in a real-time database. Furthermore, 2V-DBP-SNAP allows these data elements to be shared with soft real-time tasks, which access them using a database query lang... | Abstract This paper, investigating the goal of human-level synthetic intelligence, presents a novel approach to learning an associative memory model using Generalized Hough Transform (GHT) [1] . A human action detection and classification system is also constructed to verify the effectiveness of the proposed GHT-based ... |
In this paper we propose an improvement to the GRPW algorithm for wireless sensor networks called GRPW-M , which collects data in a wireless sensor network (WSN) using a mobile nodes. Performance of GRPW algorithm algorithm depends heavily on the immobile sensor nodes . This prediction can be hard to do. For that reaso... | This paper presents a novel convergecast algorithm called, Virtual Circle Combined Straight Routing (VCCSR), which collects data in a wireless sensor network (WSN) using a mobile sink. Tree-based routing offers the shortest routes to deliver data, and it is a common scheme used by mobile sinks to collect data from sens... | Online data acquisition, data assimilation and integrated hydrological modelling have become more and more important in hydrological science. In this study, we explore cloud computing for integrating field data acquisition and stochastic, physically-based hydrological modelling in a data assimilation and optimisation f... |
Recurrent event data are quite common in biomedical and epidemiological studies. A significant portion of these data also contain additional longitudinal information on surrogate markers. Previous studies have shown that popular methods using a Cox model with longitudinal outcomes as time‐dependent covariates may lead ... | : In this work, we study the event occurrences of individuals interacting in a network. To characterize the dynamic interactions among the individuals, we propose a group network Hawkes process (GNHP) model whose network structure is observed and fixed. In particular, we introduce a latent group structure among individ... | Over five years, from 1919 to 1924, Freud dealt with masochism in three texts written in close proximity: “A Child Is Being Beaten,” Beyond the Pleasure Principle, and “The Economic Problem of Masochism.” Initially Freud explains masochism as incestuous fixation on the father and regression to pregenital, sadistic ways... |
A causal association of high risk HPV persistent infections with cervical cancer is firmly established by epidemiological and experimental evidence. Since HPV is considered a necessary factor for cervix carcinoma development and disease severity, the HPV DNA persistence may represent an indicator of both therapy effect... | OBJECTIVE
The aims of this study were (1) to examine whether HPV DNA is persistently detected in the cervix after therapeutic conization for CIN 3 and (2) to explore whether a patient with persistence of HPV infection is at risk of developing recurrent disease.
METHODS
Of 74 patients referred with CIN 3, 58 who were ... | Protein from silkmoth pupal fat body was used to develop a simple radioisotope-competition binding assay for cGMP, with increased sensitivity and specificity over the currently used protein binding assay (2). With this assay, we have initiated a study of the distribution of cGMP in crickets, which contain unusually hig... |
ABSTRACT Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms. RNA interference (RNAi) is a sequence-specific RNA degradation ... | Summary: RNA interference (RNAi) is known to play an important part in defence against viruses in a range of species. Second-generation sequencing technologies allow us to assay these systems and the small RNAs that play a key role with unprecedented depth. However, scientists need access to tools that can condense, an... | ABSTRACT The VP6 protein of bluetongue virus possesses a number of activities, including nucleoside triphosphatase, RNA binding, and helicase activity (N. Stauber, J. Martinez-Costas, G. Sutton, K. Monastyrskaya, and P. Roy, J. Virol. 71:7220-7226, 1997). Although the enzymatic functions of the protein have been docume... |
TITANIUM occurs widely in the Earth's crust, traces of it being present in most rocks, soils and clays. It is estimated that titanosilicate minerals alone number more than 100; but, remarkably, in only one of these does the Ti(IV) ion take up fivefold coordination. This is in fresnoite1 (Ba2TiSi2O8), which contains squ... | Dibarium dititanium difluoride dioxide heptaoxidodisilicate, Ba(2)Ti(2)Si(2)O(9)F(2), is a new edge-sharing titanate with a unique titanium silicate framework. All atoms in the structure are in general positions. Titanium oxyfluoride octahedra combine with silicon tetrahedra to form a double stacked chain, which is the... | Abstract Nutrient information concerning the specific needs in fermentation broth is crucial to the potency and production of an antibiotic. Nutrient analysis of carbohydrate metabolism by HPLC is hindered by an array of fermentation broth interferences. These interferences can be effectively removed by solid-phase ext... |
Despite extensive studies, there are still many unanswered questions regarding the mechanism of hedgehog signaling and the phylogenic conservation of hedgehog function in vertebrates. For example, whether hedgehog signaling in vertebrates requires smoothened is unclear, and the role of hedgehog activity in zebrafish is... | Zebrafish you-too (yot) mutations interfere with Hedgehog (Hh) signaling during embryogenesis. Using a comparative synteny approach, we isolated yot as a zinc finger transcription factor homologous to the Hh target gli2. Two alleles of yot contain nonsense mutations resulting in carboxy-terminally truncated proteins. I... | In a previous paper we reported early immunoregulatory mechanisms involving not only the appearance of progressive suppression but also significant increases in alloreactive T levels in paraaortic lymph nodes (PALN) and spleen, not only in allogeneic but also in syngeneic pregnancies. Taking into account the hypothesis... |
To the Editor: We completely agree with the critical point of view expressed by Dr Singh regarding the new challenges raised by epoetin-a’s copies known as follow-on epoetin. However, we would like to stress the point that the qualification of Wepox (Wockhardt Limited, Mumbai, India) as a ‘biosimilar’ is probably not f... | The first generation of biopharmaceuticals has begun to lose patent protection. Richard Frank writes that there is concern that without new U.S. regulations, patent expirations may not be accompanied by the introduction of competing, lower-cost biologic agents, or that imitator products might be approved without suffic... | Our research aimed to evaluate the efficacy of anthelmintic treatments in sheep, as well as the resistance occurrence risk for the most commonly used substances. Anthelmintic medication efficacy was evaluated on 30 animals from a private farm, located in Sânmihaiu Almaşului, Sălaj County. In vivo studies were performed... |
Transmission lines with time-varying reactance exhibit interesting behaviors such as parametric amplification and mixing [1]. In this paper, such a transmission line realized with distributedly modulated capacitors (DMC) is demonstrated with its active conversion gain, low noise figure as well as non-reciprocity. DMC i... | The concept of distributedly modulated capacitors (DMC) is proposed as a form of time-varying transmission-line structure offering nonreciprocal propagation and coupling characteristics. The nonreciprocity is achieved by taking advantage of the additional dimension of time-variance in the transmission-line property. Th... | Nonlinear transmission lines (NLTL) are used for pulse shaping. We developed the theory of pulse propagation through the NLTL. The problem of a wide pulse degenerating into multiple pulses rather than a single pulse is solved by using a gradually scaled NLTL. We exploit certain favorable properties of accumulation-mode... |
A simple but efficient method for highly sensitive Raman detection, covering a thin polydimethylsiloxane elastomer, pre-coated with a layer of Au or Ag nanoparticles, onto the detected substrate, is proposed. Moreover, this nanoparticle-coated PDMS elastomer can be used for chemical imaging with high sensitivity. | Self-assembled monolayers (SAMs) form when organic molecules spontaneously chemisorb on the surfaces of solids (e.g. organic thiols and disulfides on gold, silver, and copper or carboxylic acids on the surface of alumina).1'2 The most robust and best characterized SAMs are those comprising alkanethiolates on gold.l By ... | In this paper, we demonstrate how one can chemically design Raman dye-functionalized nanoparticle probes with specific protein-binding affinities and use these probes, coupled with surface-enhanced Raman scattering (SERS) spectroscopy, to perform multiplexed screening of protein-small molecule interactions and protein-... |
One of the central considerations to be taken into account in evaluating the ethics of compensation for donated plasma is respect for donor autonomy. And one of the main arguments against compensated donation systems is that many donors do or would come from circumstances of poverty that restrict their alternatives in ... | In this paper I develop and defend my arguments in favor of the moral permissibility of a legal market for human body parts in response to the criticisms that have been leveled at them by Paul M. Hughes and Samuel J. Kerstein. | Much of the literature devoted to the topics of agent autonomy and agent responsibility suggests strong conceptual overlaps between the two, although few explore these overlaps explicitly. Beliefs of this sort are commonplace, but they mistakenly conflate the global state of being autonomous with the local condition of... |
Xylan is the second most abundant polysaccharide in dicot wood. Unraveling the biosynthetic pathway of xylan is important not only for our understanding of the process of wood formation but also for our rational engineering of wood for biofuel production. Although several glycosyltransferases are implicated in glucuron... | Xylan is a major cross-linking hemicellulose in secondary walls of vascular tissues, and the recruitment of xylan as a secondary wall component was suggested to be a pivotal event for the evolution of vascular tissues. To decipher the evolution of xylan structure and xylan biosynthetic genes, we analyzed xylan substitu... | This article focuses on described video (DV), which makes television accessible to persons who are blind or who have low vision by providing voice-over descriptions of shows. The article highlights the lack of DV content in Canada and outlines the factors inhibiting more DV production, including policy, the commercial ... |
Infrared (IR) cameras have wide range of applications, but high cost and low performance of its core component, IR detectors, prevent theirs broad usages in various fields. Motivated by this challenge, a carbon nanotube (CNT) based multiple spectrum IR camera was developed, which used nano-size CNT as the functional el... | We report the development of high-speed carbon nanotube (CNT) based infrared (IR) sensors which operate at room temperature. When a single CNT is manipulated between two different metal electrodes, a Schottky diode is formed at the CNT-metal interface, so photocurrent is generated when there is IR illumination. The dev... | Linear systems methodology is proposed which quantifies flare as part of the spread function or Modulation Transfer Function (MTF) of a microdensitometer with general application to any optical detection system. Because the irradiance system, the sample's scattering properties and the optical components alter the flare... |
The hallmark of Engineering Technology (ET) programs is its student-centered curriculum and hands-on approach to teaching. Many institutions with ET programs now require scholarship of their ET faculty in addition to their teaching duties. In many institutions that have always emphasized scholarship and research, under... | The establishment of formal research programs for undergraduate engineering students is one way to encourage critical thinking, life-long learning, and the pursuit of graduate education. This paper discusses issues associated with the participation of undergraduates in engineering research, and describes the highly suc... | Aalborg University in the north Jutland region of Denmark was chartered in 1974 and represents an innovative educational experiment with project-based teaching concepts. The University opened with approximately 900 students and currently enrolls an estimated 10,000. This paper examines how project-based teaching at Aal... |
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the transcription factors OCT4, SOX2, and NANOG. In addition to regulating each other through feedback loops, these genes also r... | Parameter estimation is a challenging computational problem in the reverse engineering of biological systems. Because advances in biotechnology have facilitated wide availability of time-series gene expression data, systematic parameter estimation of gene circuit models from such time-series mRNA data has become an imp... | Exposure to environmental contaminants such as activators of the aryl hydrocarbon receptor (AhR) leads to the induction of defense and detoxification mechanisms. While these mechanisms allow organisms to metabolize and excrete at least some of these environmental contaminants, it has been proposed that these mechanisms... |
As the severity of natural catastrophes continues to intensify, disaster risk management is becoming increasingly important. In order to expand the capacity of the insurance markets, insurers and reinsurers have utilized alternative risk financing mechanisms such as catastrophe (CAT) bonds. Although the CAT bond market... | This paper discusses the recent changes in the market for catastrophe risk. These risks have traditionally been distributed through the insurance and reinsurance systems. However, because insurance companies tend to share relatively small amounts of their cat exposures and because insurance companies' capital is threat... | Value at Risk has become the standard measure of market risk employed by financial institutions for both internal and regulatory purposes. Despite its conceptual simplicity, its measurement is a very challenging statistical problem and none of the methodologies developed so far give satisfactory solutions. Interpreting... |
Current methods for producing clinical guidelines are cumbersome and not always reliable. Could a more streamlined approach improve coverage and make decisions more transparent? | I this issue of Medical Decision Making, Taffe and colleagues describe a study of the clinical and economic factors influencing the assessments of appropriateness made by clinicians as part of an application of the RAND-UCLA appropriateness method for assessing the use of preoperative erythropoietin in elective orthope... | As the proportion of older patients with frailty presenting to health services increases, so does the need for doctors to be adequately trained to meet their needs. The presentations seen in such patients, the evidence-based models of care and skillsets required to deliver them are different than for younger patient gr... |
Limitations imposed by the traditional practice in financial institutions of running risk analysis on the desktop mean many rely on models which assume a normal Gaussian distribution of events which can seriously underestimate the real risk. In this paper, we propose an alternative service which uses the elastic capaci... | This paper introduces a cloud broker service (STRATOS) which facilitates the deployment and runtime management of cloud application topologies using cloud elements/services sourced on the fly from multiple providers, based on requirements specified in higher level objectives. Its implementation and use is evaluated in ... | Sort is a fundamental kernel used in many database operations. In-memory sorts are now feasible; sort performance is limited by compute flops and main memory bandwidth rather than I/O. In this paper, we present a competitive analysis of comparison and non-comparison based sorting algorithms on two modern architectures ... |
We have developed a methodology of prodrug delivery by using a modified insulin species whose biological activity potentially can be regulated in vivo. Native insulin was derivatized with aldol-terminated chemical modifications that can be selectively removed by the catalytic aldolase antibody 38C2 under physiologic co... | Three-phase partitioning (TPP) treated aldolase antibody 38C2 was evaluated for aldol reaction between p-nitrobenzaldehyde and acetone to give 4-(4'-nitrophenyl)-4-hydroxy-2-butanone. While TPP-treated 38C2 transformed 65% of p-nitrobenzaldehyde, the untreated 38C2 gave only 24% transformation in 18 h at 25 degrees C. ... | The keto–enol tautomerism of some β-dicarbonyl compounds, including ethyl acetoacetate (1), acetylacetone (2), benzoylacetone (3), dibenzoylmethane (4), and 1,1,1-trifluoro-3-(2-thenoyl)acetone (5), has been investigated in various solvents at 25 °C, by using low-temperature (–20 to –50 °C) high-performance liquid chro... |
BackgroundRoutes of transmission of multidrug-resistant gram-negative organisms (MDRGN) are not completely understood. Since sexual transmission of MDRGN might represent a potential mode that has not been noticed so far, this study evaluated transmission of MDRGN in HIV positive men.MethodsBetween November 2014 and Mar... | Increased antimicrobial resistance among Human Immunodeficiency Virus (HIV)-infected individuals to commonly used antibiotics in the treatment of gastroenteritis is a public health concern, especially in resource-limited settings. We set out to compare the antimicrobial susceptibility pattern of Escherichia coli (E. co... | In this paper I examine whether a society can improve welfare by imposing a legal restriction to forbid the use of nominal bonds as a means of payments for goods. To do so, I integrate a microfounded model of money with the framework of limited participation. While the asset market is Walrasian, the goods market is dec... |
Potato starch and both untreated and decationized dextrose syrups were used as substrates for submerged citric acid biosynthesis using a mutant of Aspergillus niger. The same yield of product (80%) was achieved with both syrups and the starch despite having different trace metals content. The obtained mutant was more s... | The filamentous ascomycete Aspergillus niger is well known for its ability to accumulate citric acid for the hydrolysis of starchy materials. To improve citric acid productivity, heavy ion beam mutagenesis was utilized to produce mutant A.niger strains with enhanced production of citric acid in this work. It was demons... | Abstract. The projected increase in sewage sludge used on land within many countries in the European Community will provide a major source of entry for several heavy metals into the soil. Although the application rate of sewage sludge to agricultural land is constrained by maximum annual additions of heavy metals, ther... |
Driven by the need for high data-rates and improved cell coverage, mobile phone filters are required to process increasingly high RF power levels. The simultaneous demand for smaller filter footprints makes designing a filter for high-power performance a challenge. We report a method for simulating the self-heating eff... | This paper reviews recent progress of temperature compensated surface acoustic wave (SAW) devices for wireless communications. First, temperature compensation techniques based on the SiO2 deposition and the wafer bonding are explained, and their implementation into real devices are discussed. Finally, we will show how ... | In this paper, the reliability requirements, thermal behaviour and failure mechanisms of solidly mounted Bulk Acoustic Wave (BAW) filters are studied. High power RF stress measurements are presented where the evolution of the surface damage of the BAW filters as a function of stress time is analysed by optical height p... |
BackgroundUnilateral absence of the pulmonary artery (UAPA) is a rare congenital malformation often associated with other cardiac anomalies; however it may occur as an isolated lesion. Isolated absence of the right pulmonary artery is twice more frequent than that of the left pulmonary artery. Patients with isolated UA... | The isolated unilateral absence of a proximal pulmonary artery is a rare congenital lesion with a diverse clinical presentation. If the connecting ductus arteriosus closes after birth, the ipsilateral pulmonary artery will lose its source of blood supply, resulting in hypoplasia or obliteration of intrapulmonary vessel... | OBJECTIVE:Esomeprazole, the S-isomer of omeprazole, achieves a significantly greater healing rate and symptom resolution of erosive esophagitis than that achieved by omeprazole. The objective of this study is to assess the efficacy of the new proton pump inhibitor esomeprazole in preventing relapse over a prolonged per... |
Over fifteen years after first reporting to the State of New York, the Harvard Medical Practice Study (HMPS) continues to have a significant impact in medical malpractice policy debates. In those debates the HMPS has come to stand for four main propositions. First, “medical injury ... accounts for more deaths than all ... | OBJECTIVES
Peer review is used to make final judgments about quality of care in many quality assurance activities. To overcome the low reliability of peer review, discussion between several reviewers is often recommended to point out overlooked information or allow for reconsideration of opinions and thus improve relia... | Historically, the goal of most descriptive research on learning disabilities has been to document intellectual or neurological differences between learning disabled and normal children. However, most researchers and teachers would acknowledge that classroom achievement not only depends on cognitive skills but also on c... |
A series of 137 urine samples were analyzed for drugs of abuse by enzyme immunoassay (EMIT) and by gas chromatography/mass spectrometry (GC/MS). Agreement between these methods was excellent and ranged from 93.4% for benzodiazepines to 98.5% for propoxyphene. EMIT false negative were traced to the presence of elevated ... | Homogenous enzyme immunoassay (EMIT) reagents for the detection of amphetamines, benzodiazepines, cocaine metabolite, methadone, opiates and dextropropoxyphene in urine were evaluated using an automated clinical analyser. Reproducibility of analyses was excellent, specificity good, and interference from unrelated drugs... | The haptenic group morphine was coupled to a protein and the conjugate possessed immunogenic properties. The method for preparing the carboxymethylmorphine protein conjugate is described. Evidence is presented for the formation of antibodies with specificity for the alkaloid as demonstrated by precipitin reaction and b... |
AIMS To assess the effects of the nitric oxide donor 5-isosorbide mononitrate (ISMO) on blood flow in the optic nerve head (ON flow) and choroid (Ch flow). METHODS Laser Doppler flowmetry was used to measure ON flow and Ch flow in 12 normal subjects by aiming the laser beam at the fovea and at the temporal rim, respect... | PURPOSE
To evaluate the ocular surface toxicity of two nitric oxide donors in ex vivo and in vivo animal models: S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine (SNAC) in a hydroxypropyl methylcellulose (HPMC) matrix at final concentrations 1.0 and 10.0 mM.
METHODS
Ex vivo GSNO and SNAC toxicities were cli... | The short-range order (SRO) correlations in liquid- and rotator-phase states of carbon tetrachloride are revisited here. The correlation of some angular magnitudes is used to evaluate the positional and orientational correlations in the liquid as well as in the rotator phase. The results show significant similitudes in... |
The heterogeneity of a network causes major challenges for link prediction in heterogeneous complex networks. To deal with this problem, supervised link prediction could be applied to integrate heterogeneous features extracted from different nodes/relations. However, supervised link prediction might be faced with highl... | Recently, some algorithms have been reported for mining multi-graph Frequent Approximate Subgraphs (FASs). This kind of algorithm has a large applicability in social network analysis, image classification tasks and clustering, among others. However, all of them mine a large number of patterns. For this reason, some alg... | We introduce a novel Bayesian probabilistic peak detection algorithm for liquid chromatography-mass spectroscopy (LC-MS). The final probabilistic result allows the user to make a final decision about which points in a chromatogram are affected by a chromatographic peak and which ones are only affected by noise. The use... |
A peculiar echocardiographic pattern was recorded in a case of cystic teratoma of the left anterior and upper mediastinum, causing a mild stenosis at the pulmonary valve level. The usefulness of echocardiography in the evaluation of anterior mediastinal masses as they distort normal cardiac anatomy is discussed. | A report is presented of the occurrence of peripheral pulmonary stenosis due to tumour compression in a 12 year-old boy. The tumour was identified as a liposarcoma of the mediastinum, which caused complete occlusion of the left pulmonary artery and stenosis of the right pulmonary artery. This was followed by an extreme... | Four cases of pulmonary artery stenosis resulting from extrinsic pressure are presented. All of these cases presented with the triad of chest pain, dyspnoea, and a pulmonary systolic murmur. Respiratory variation of this murmur was noted in three of the patients, the murmur increasing during expiration and diminishing ... |
This paper describes the design and the implementation of the EduWel survey project which took place during the PhD programme of the EduWel Early Stage Researchers (ESRs), between September 2010 and July 2013. The project had two main purposes: to design and implement a pilot survey for the detection and study of certa... | Introduction 1. Education Policy Issues 2. Sen's Capability Approach 3. Blending Sen and Bourdieu 4. Evolving Theory into Method 5. The Nature of Aspirations 6. The Genesis of Capabilities 7. Aspirations, Capabilities and Choice 8. The Promise of Higher Education 9. The New Pursuit of Justice Bibliography Index | The objective of this study was to record the prevalence rate of Cryptosporidium and to determine the Cryptosporidium spp in cattle in different parts of Baghdad province. A total number of 100 fecal samples from different age groups were collected. Conventional method using modified Ziehl-Neelsen for staining fecal sm... |
The design and analytical modeling of a high efficiency energy harvester comprising a passive voltage-boosting network (VBN) and a switching charge pump rectifier (CPR) is presented in this paper. To improve the power conversion efficiency (PCE), the VBN increases the voltage at the input of the CPR and provides contro... | A multi-band autonomous wireless sensor node (AWSN) with temperature monitoring is designed in a standard 0.18 μm CMOS technology. The AWSN comprises a high efficiency energy harvester, a power management module, a temperature-to-time converter (TTC) and a passive 402-MHz MICS band OOK transmitter for backscattering tr... | In this paper, a 60-GHz CMOS RFIC-on-chip triangular monopole antenna is presented. A planar triangular-monopole structure fed by the CPW line is adopted to design the on-chip antenna. The FEM-based 3D full-wave EM solver, Ansoft HFSS, is used for the design simulation. The antenna chip is fabricated with a 0.18-mum CM... |
In Europe, more than 250,000 university students spend one or two semesters abroad every year. This study explores whether a short time abroad contributes to the acquisition of foreign language proficiency. We use a newly available dataset about almost the totality of Italian graduates and two alternative instruments t... | Despite the great popularity of international educational mobility schemes, relatively little research has been conducted to explore their benefits. Using data on a large sample of recent Italian graduates, this paper investigates the extent to which participation in study abroad programs during university studies impa... | Several studies have argued that learning a foreign language has the potential to increase the general cognitive ability and test scores of students. In this analysis, the Mormon missionary program is used to test whether or not students who were assigned to learn a foreign language performed better in college. The res... |
The complement system was discovered toward the end of the nineteenth century as a heat-labile principle in fresh nonimmune serum which was essential for the bactericidal activity of serum from immunized guinea pigs. It has subsequently been established as a very important factor of constitutive immunity. The complemen... | Abstract C2 and Factor B were highly purified from human plasma by sodium sulfate precipitation, conventional column Chromatographie techniques and preparative electrophoresis on polyacrylamide gels. Both proteins behaved as single polypeptide chains of mol. wt 116, 900 and 93, 000 dallons respectively. Highly purified... | Abstract A technique of agar-gel electrophoresis possessing a high resolving power is described whereby a minimum of nine fractions are revealed in normal human serum. This is achieved by using a steep voltage gradient so as to complete the electrophoretic separation in less than 30 min. A very efficient, inexpensive c... |
We present a framework which enables the combination of different mobile devices into one multi-display such that visual content can be shown on a larger area consisting, e.g., of several mobile phones placed arbitrarily on the table. Our system allows the user to perform multi-touch interaction metaphors, even across ... | This contribution proposes a definition and taxonomy of the often used term cross-device interaction. Despite of technical progress, systems and interfaces that integrate into the environment are still the subject of intensive research. We still live in a world where devices reside in the foreground and present themsel... | This research explores distributed sensing techniques for mobile devices using synchronous gestures. These are patterns of activity, contributed by multiple users (or one user with multiple devices), which take on a new meaning when they occur together in time, or in a specific sequence in time. To explore this new are... |
Data aggregation protocols can reduce the communication cost, thereby extending the lifetime of sensor networks. Prior works on data aggregation protocols have focused on tree-based or cluster-based structured approaches. Although structured approaches are suited for data gathering applications, they incur high mainten... | Wireless Sensor Networks (WSNs) are formed by a large collection of power-conscious wireless-capable sensors without the support of pre-existing infrastructure, possibly by unplanned deployment. With a sheer number of sensor nodes, their unattended deployment and hostile environment very often preclude reliance on phys... | In the past decades ancient DNA research has brought numerous insights to archaeological research where traditional approaches were limited. The determination of sex in human skeletal remains is often challenging for physical anthropologists when dealing with incomplete, juvenile or pathological specimens. Molecular ap... |
Rates of cannabis use in Canada are among the highest in the Western world. Past year use among Canadian youth is estimated to be approximately 25%, with up to 28% of children aged 11 to 15 years reporting cannabis use, the highest rate among developed countries. Moreover, 43% of Canadians currently endorse lifetime ca... | IMPORTANCE
As of March 2015, 23 states and the District of Columbia had medical marijuana laws in place. Physicians should know both the scientific rationale and the practical implications for medical marijuana laws.
OBJECTIVE
To review the pharmacology, indications, and laws related to medical marijuana use.
EVIDE... | The mechanism of mitral valve area increase by double balloon mitral valvotomy in vitro has not been defined, nor have the mitral valve area results achieved by single versus double balloon mitral valvotomy technique been compared. After a selection of 29 intact mitral valves excised at cardiac surgery from patients wi... |
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