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Significance Unimolecular hydrogen shift reactions to peroxy radicals have been shown to be important in the atmospheric photooxidation of isoprene and α-pinene. These studies also report the efficient generation of highly oxidized organic molecules known to contribute to particle formation and growth. Here, we quantif... | Anthropogenic emissions and land use changes have modified atmospheric aerosol concentrations and size distributions over time. Understanding preindustrial conditions and changes in organic aerosol due to anthropogenic activities is important because these features (1) influence estimates of aerosol radiative forcing a... | We found that metal-organic framework (MOF) compounds M(2)(dhtp) (open metal M = Mg, Mn, Co, Ni, Zn; dhtp = 2,5-dihydroxyterephthalate) possess exceptionally large densities of open metal sites. By adsorbing one CH(4) molecule per open metal, these sites alone can generate very large methane storage capacities, 160-174... |
Synthetic alkyl-lysophospholipids, represented by edelfosine (ED), reveal strong anticancer activity and therefore are promising drugs used in anticancer therapy. Primary target for edelfosine is cellular membrane, which is in contrast to traditional cytostatics affecting DNA. The mechanism of antitumor activity of ede... | Cyclosporin A (CsA), a hydrophobic peptide, mainly known for its immunosuppressant properties, has shown a broad range of biological activities, including antimalarial action. Since CsA was found to be active on membrane level, it was subjected for investigations involving membrane models. Our former studies on interac... | Drug-induced liver injury (DILI) is the most common organ toxicity encountered in regulatory animal toxicology studies required prior to the clinical development of new drug candidates. Very few reports have evaluated the value of these studies for predicting DILI in humans. Indeed, compounds inducing liver toxicity in... |
Kinematic features of the handwriting process are promising for discriminating patients probably affected by neurodegenerative disorders from healthy controls and potentially for identifying the stage of the illness. Many tasks have been proposed and tested, however the scientific community still lacks a complete proto... | Mole pattern changes are important elements in detecting cancerous skin lesions, the early stage detection is a key factor to completely cure the pathology. In this paper, an automatic system for mole-tracking is indicated. The method presented is been realized as a mobile app and can be used to perform periodically a ... | Monocyclic monomers bearing exo-methylene groups are likely to undergo ring-opening polymerization under the conditions of radical or cationic initiation. Several structural features will determine the course of reaction after initiation by species that exclusively attack the exo-methylene functionality. Reviewing some... |
The frequency distribution of words has been a key object of study in statistical linguistics for the past 70 years. This distribution approximately follows a simple mathematical form known as Zipf’s law. This article first shows that human language has a highly complex, reliable structure in the frequency distribution... | About eight decades ago, Zipf postulated that the word frequency distribution of languages is a power law, i.e., it is a straight line on a log-log plot. Over the years, this phenomenon has been documented and studied extensively. For many corpora, however, the empirical distribution barely resembles a power law: when ... | In the remote sensing, supervised deep learning has recently achieved great success of information extraction. However, it requires a large training data in order to effectively learn. In building change classifications, collecting such training data is an extremely expensive and time-consuming process, because of the ... |
Downlo hanisms by which c-Myc (Myc) amplification confers aggressive medulloblastoma phenotypes are poorned. Here, we show using orthotopic models that high Myc expression promotes cell migration/invasion duces metastatic tumors, which recapitulate aggressive histologic features of Myc-amplified primary medulloblastoma... | Tumor angiogenesis, a major requirement for tumor outgrowth and metastasis, is regulated by pro- and antiangiogenic factors. Methylation-associated inactivation of the angiogenesis inhibitor thrombospondin-1 (TSP-1) has been observed recently in some adult tumors. To investigate the role of TSP-1 in pediatric cancer, w... | Rabphilin-3A is a putative target protein for Rab3A small GTP-binding protein which is implicated in neurotransmitter release. Rabphilin-3A is expressed mainly in brain, but its subcellular localization remains to be clarified. Immunohistochemical analysis has revealed that Rabphilin-3A is most abundant in the synaptic... |
In the recent years there has been a surge of research activity in the area of information retrieval on the World Wide Web, using link analysis of the underlying hypertext graph topology. Most of the algorithms in the literature can be described as a dynamical system, that is, the repetitive application of a function o... | Web search algorithms that rank Web pages by examining the link structure of the Web are attractive from both theoretical and practical aspects. A link-based search algorithm A is rank-stable if minor changes in the link structure of the input graph, which is usually a subgraph of the Web, do not aaect the ranking it p... | Energy consumption and efficiency emerged as the hottest topic in the context of China's sustainable development. Energy subsidies and “rebound effect” were closely related to this topic while few combinative studies on them with a focus on China. This paper employed a co-thinking approach, focusing on how the energy s... |
Scutellaria baicalensis (SB), a traditional herb with high pharmacological value, contains more than 10% flavone by weight. To improve the biological activity of flavones in SB, we aimed to enhance the bioconversion of baicalin (BG) to baicalein (B) and wogonoside (WG) to wogonin (W) in SB during fermentation using bet... | The beta-glucuronidase (GUS) gene from Lactobacillus brevis RO1 was cloned and expressed in Escherichia coli GMS407. The GUS gene was composed of 1812 bp, encoding a 603-amino-acid protein belonging to the glycosyl hydrolase family 2 with three conserved domains. The amino acid similarity was higher than 70% with the b... | Objectives: To determine the effect of watching Turkish comedy films on postoperative pain and anxiety in oncology surgical patients. Design: This study was conducted using a pre- and post-test randomized controlled trial model. Materials and Methods: The study was conducted in a general surgery clinic of a hospital in... |
A multimode loop antenna with compact volume for mobile applications is presented in this paper. The loop antenna consists of a loop strip with a length of about 0.5λ. The loop strip is meandered to save space and bent to generate three traditional resonant modes, the 0.5-λ, 1-λ and 1.5-λ modes, and an additional highe... | A small-size coupled-fed loop antenna suitable to be printed on the system circuit board of the mobile phone for penta-band WWAN operation (824-960/1710-2170 MHz) is presented. The loop antenna requires only a small footprint of 15 x 25 mm2 on the circuit board, and it can also be in close proximity to the surrounding ... | The human intestinal microbiota is essential to the health of the host and plays a role in nutrition, development, metabolism, pathogen resistance, and regulation of immune responses. Antibiotics may disrupt these coevolved interactions, leading to acute or chronic disease in some individuals. Our understanding of anti... |
Whole-cell recordings were used to investigate the effects of a 3-week period of hypoxia (10% O2) on the properties of K+ and Ca2+ currents in type I cells isolated from adult rat carotid bodies. Chronic hypoxia significantly increased whole-cell membrane capacitance. K+ current amplitudes were not affected by this per... | Acute O2 sensing is necessary for the activation of cardiorespiratory reflexes (hyperventilation and sympathetic activation), which permit the survival of individuals under hypoxic environments (e.g. high altitude) or medical conditions presenting with reduced capacity for gas exchange between the lung alveoli and the ... | 1. During osmotic swelling, cultured osteoblastic cells (ROS 17/2.8) exhibited activation of large amplitude Cl‐ currents in the whole‐cell configuration of the patch‐clamp technique. Effects of hypotonic shock on cell volume and membrane conductance were rapidly reversed on return to isotonic conditions. 2. Voltage co... |
ii | Youth at two schools (St. John, USVI and West Liberty, IA) participated in the I Grow Culture Pen Pal Program. The purpose of the 9-week program was to evaluate middle school student’s increase in knowledge and confidence related to communicating local gardening, cultural understanding and sustainability. The collabora... | A study examined the impact of written feedback on goals and self-efficacy, and the impact of goals and self-efficacy on changes in writing performance. Subjects were 137 students in a second-semester freshman-level college English composition class and 5 second-semester graduate assistant teachers. Consistent with soc... |
MOLECULAR outflow is an energetic mass-ejection phenomenon associated with very early stage of stellar evolution1,2. The large kinetic energy involved in the phenomenon indicates that outflow may play an essential role in the process of star formation, particularly by extracting angular momentum3. Most of the previous ... | The early phases of stellar evolution are frequently characterized by vigorous interaction between the nascent star and its environment, resulting in the formation of molecular outflows, highly collimated jets, Herbig-Haro objects and small emission or reflection nebulae. A deep survey of such small nebulae around youn... | In this work, antibacterial and anti-adhesive polymeric thin films were constructed on polyacrylonitrile (PAN) nanofibrous membranes in order to extend their applications. Polyhexamethylene guanidine hydrochloride (PHGH) as an antibacterial agent and heparin (HP) as an anti-adhesive agent have been successfully coated ... |
This paper presents the state of the art for oil spill detection in the world oceans. We discuss different satellite sensors and oil spill detectability under varying conditions. In particular, we concentrate on the use of manual and automatic approaches to discriminate between oil slicks and look-alikes based on patte... | Compact polarimetry is a technique that allows construction of pseudo quad-pol information from dual-polarization synthetic aperture radar (SAR) systems. Compact polarimetry showed promise of being able to reduce the complexity, cost, mass, and data rate of a SAR system while attempting to maintain many capabilities of... | In cluster analysis, determining number of clusters is an important issue because information about the most appropriate number of clusters do not exist in the real-world problems. Automatic clustering is a clustering approach which is able to automatically find the most suitable number of clusters as well as divide th... |
In previous studies classification algorithms were employed successfully for the detection of unknown malicious code. Most of these studies extracted features based on byte n-gram patterns in order to represent the inspected files. In this study we represent the inspected files using OpCode n-gram patterns which are ex... | The proliferation of malware has presented a serious threat to the security of computer systems. Traditional signature-based anti-virus systems fail to detect polymorphic/metamorphic and new, previously unseen malicious executables. Data mining methods such as Naive Bayes and Decision Tree have been studied on small co... | Many anti-phishing mechanisms currently focus on helping users verify whether a Web site is genuine. However, usability studies have demonstrated that prevention-based approaches alone fail to effectively suppress phishing attacks and protect Internet users from revealing their credentials to phishing sites. In this pa... |
BackgroundWe describe a hierarchical clustering algorithm for using Single Nucleotide Polymorphism (SNP) genetic data to assign individuals to populations. The method does not assume Hardy-Weinberg equilibrium and linkage equilibrium among loci in sample population individuals.ResultsWe show that the algorithm can assi... | Inferring the structure of populations has many applications for genetic research. In addition to providing information for evolutionary studies, it can be used to account for the bias induced by population stratification in association studies. To this end, many algorithms have been proposed to cluster individuals int... | This book is an opportunity to read narratives about social interactions in multicultural settings, and to discuss the role they play in the construction of school and social achievement. It is not only a book on multiculturality. It is also a multicultural book, including an introduction and 13 chapters from authors r... |
The increase of microbial resistance to antibiotics has led to a continuing search for newer and more effective drugs. Antimicrobial peptides are generally found in animals, plants, and microorganisms and are of great interest to medicine, pharmacology, and the food industry. These peptides are capable of inhibiting pa... | Termites are mainly known for damage caused to human beings, both in urban and rural areas. However, these insects play an important role in the decomposition of organic matter in tropical regions and are important natural resources, which are widely used in traditional medicine and are also consumed by human populatio... | Antisperm antibodies (ASA) are present in 20% of couples seeking treatment for infertility. Antibody-binding proteins in seminal plasma may protect sperm from ASA-induced damage. We have previously isolated several IgG-binding proteins from human seminal plasma using IgG affinity chromatography. Here, we report another... |
Reprogramming metabolism of tumor cells is a hallmark of cancer. Lactate dehydrogenase A (LDHA) is frequently overexpressed in tumor cells. Previous studies has shown higher levels of LDHA is related with colorectal cancer (CRC), but its role in tumor maintenance and underlying molecular mechanisms has not been establi... | BackgroundOver 90% of cancer-related deaths in clear cell renal cell carcinoma (RCC) are caused by tumor relapse and metastasis. Thus, there is an urgent need for new molecular markers that can potentiate the efficacy of the current clinical-based models of prognosis assessment. The objective of this study is to evalua... | This article discusses a unique organization in the regulatory world, the Brazilian Association of Regulatory Agencies (ABAR), which brings together federal, state, and municipal regulatory agencies across different policy sectors. The paper argues that as a regulatory policy network, ABAR has been crucial to the profe... |
Membrane skeletons are structural elements that provide mechanical support to the plasma membrane and define cell shape. Here, we identify and characterize a putative protein component of the membrane skeleton of the malaria parasite. The protein, named PbIMC1a, is the structural orthologue of the Toxoplasma gondii inn... | Alveolates are a recently recognized group of unicellular eukaryotes that unites disparate protists including apicomplexan parasites (which cause malaria and toxoplasmosis), dinoflagellate algae (which cause red tides and are symbionts in many corals), and ciliates (which are microscopic predators and common rumen symb... | An accelerated metabolism and consequent decreased activity of vitamin D3 has been considered to be responsible for the osteomalacia associated with the use of anticonvulsant drugs. To investigate the effects of sodium phenobarbital and sodium diphenylhydantoin on the activity of vitamin D, rachitic rats were dosed dai... |
Strain engineering enables modification of the properties of thin films using the stress from the substrates on which they are grown. Strain may be relaxed, however, and this can also modify the properties thanks to the coupling between strain gradient and polarization known as flexoelectricity. Here we have studied th... | Flexoelectricity is a property of all dielectric materials whereby they polarize in response to deformation gradients such as those produced by bending. Although it is generally thought of as a property of dielectric insulators, insulation is not a formal requirement: in principle, semiconductors can also redistribute ... | This paper estimates the importance of network effects in the market for Yellow Pages. I estimate three simultaneous equations: consumer demand for usage of a directory, advertiser demand for advertising and a publisher's first-order condition (derived from profit-maximizing behaviour). Estimation shows that advertiser... |
Abstract Managing the use of rural resources typically requires the consideration of a diverse set of concerns and often also the resolution of conflicts. The identification and implementation of appropriate methods of analysis could assist in defining suitable development alternatives. However, the need to consider mu... | To embody the concept of sustainability in environmental management and development planning has latterly become recognized internationally as a priority for the future. Governments in many countries have consequently dedicated substantial funds to the task of defining planning and management strategies that are sustai... | In terms of land area, urbanization has undoubtedly been the main generator of changes in land use over the greater part of the present century. Even so, our urban-orientated society, with some 80 per cent of the population living in adminis? trative urban areas, may tend to over-emphasize the scale of this change beca... |
In this research, we successfully demonstrated dexterous manipulation of sheet-like elastic objects, namely, playing cards, using a high-speed robot system. In particular, our goal was to achieve card flicking by vibrating a fingertip of a robot hand at high speed and card catching by using high-speed visual feedback b... | As jumping is an effective method of moving over rough terrain, there is much interest in building robots that can jump, and deformation of a soft robot's body is an effective method to induce jumping. Our aim was to investigate the effect of the initial deformed shape of deformation of a circular shell made of spring ... | Most current techniques for the robotic manipulation of nonrigid objects require the acquisition of detailed physical models prior to manipulation. In an effort to avoid the problems caused by such modeling, a three-phase paradigm based on human coordination studies has recently been reported. However, the vision-based... |
Lithium-iodine exchange on alkyl- or aryl-substituted N-tosyliodoaziridines afforded unstabilized aziridinyllithiums, which were subsequently trapped at low temperatures with a range of carbon and heteroatom electrophiles affording cis-substituted aziridines exclusively. When using isocyanates as electrophiles, access ... | Abstract A conceptually novel, high‐yielding, mono‐ or bis‐homologation was realized with lithium halocarbenoids and enables the one‐step, fully chemocontrolled assembly of a new class of quaternary trifluoromethyl aziridines. Trifluoroacetimidoyl chlorides (TFAICs) act as convenient electrophilic platforms, enabling t... | Chiral herbicides consist of two or more enantiomers, which usually differ in their biological properties and behave enantioselectively in biochemical process. Scant studies have been published in the past decades to characterize the enantiomers of herbicide lactofen. In this study, a laboratory method was developed to... |
AbstractDiscovering, studying and determining the hydrogeoelectrical properties of the aquifer at the new area by using resistivity sounding parameters are difficult and need high accuracy in measurements and interpretation. The hydrogeological settings of the area of northwest Al Hurghada town are not studied on large... | Summary In the central highlands of Eritrea, the fractures derived as lineaments from digitally enhanced Landsat TM images are grouped based on their tectonic origins and relative ages into three major sets of geological structures, Set 1, Set 2 and Set 3. Set 1 comprises the oldest NNE–SSW and NW–SE trending tensile l... | In the electromagnetic compatibility behavior of power electronic converters, parasitic magnetic couplings between components are one of the main causes of dysfunctions or poor filtering. These couplings may be either conducted or near-field interferences. To handle interaction problems, full knowledge of these magneti... |
Recently, Isalam and Biswas proposed a new group key agreement (GKA) protocol for imbalanced mobile networks. In this letter, we will show that Isalam et al.’s GKA protocol is not secure. | In this letter, we show that Bresson-Chevassut-Essiari-Pointcheval's Group Key Agreement scheme does not meet the main security properties: implicit key authentication, forward secrecy and known key security. Also, we propose an improved version, which fixes the security flaws, found in the scheme. | WorkPartner is the prototype of a lightweight mobile service robot designed to work interactively with humans in outdoor environment. The mobility is based on a hybrid system, which combine benefits of both legged and wheeled locomotion to provide at the same time good terrain negotiating capability and large velocity ... |
By arranging multiple existing web services into workflows to create value-added services, automatic web service composition has received much attention in service-oriented computing. A large number of methods have been proposed for it although most of them are merely based on the matching of input-output parameters of... | The authors propose the markup of Web services in the DAML family of Semantic Web markup languages. This markup enables a wide variety of agent technologies for automated Web service discovery, execution, composition and interoperation. The authors present one such technology for automated Web service composition. | Today, a new technology is going to change the way platforms for the internet of services are designed and managed. This technology is called container (e.g. Docker and LXC). The internet of service industry is adopting the container technology both for internal usage and as commercial offering. The use of container as... |
Abstract A new species, Bembidion (?Nipponobembidion) ruruy sp. n., is described from the foot of Ruruy Volcano, Kunashir Island, Kuril Archipelago, Russia. It is only the second consubgener, being characterized by the reduced wings, the rounded elytral shoulders, and the backward position of the posterior supra-orbita... | Bembidion kmecoi sp. nov. herewith described, sister species of Bembidion farkaci Toledano & Sciaky, 1998, is the third species of the subgenus Plataphodes Ganglbauer, 1891 known from China. A key for the identification of these species is provided. Another species, B. elatum Andrewes, 1930, formerly known as Plataphod... | Abstract The only known physiological inhibitor of the Ras-Raf-MEK-ERK pathway, Raf-1 kinase inhibitor protein (RKIP), has been shown to regulate several intracellular signaling pathways in multiple cancers. It is a member of the PEMB family of proteins and is expressed in different mammalian species such as monkey, ch... |
M. ROEST ,* A . RE IN INGER , J . J . Z W A GI NG A , M. R . K ING ,§ J . W. M. H EEMSKERK– and THE B IORHEOLOGY SUBCOMMITTEE OF THE SSC OF THE ISTH *Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Transfusion Medicine and Hemostaseology, Univ... | Abstract In recent years, considerable progress has been made in understanding the mechanisms involved in platelet activation during hemostasis and thrombosis. Parallel-plate flow chambers and other microfluidic devices have markedly contributed to this insight. Conversely, such flow devices are now increasingly used t... | A majority of tissue factor (TF) on cell surfaces exists in a cryptic form (ie, coagulation function inactive) but retains its functionality in cell signaling. Recent studies have suggested that cryptic TF contains unpaired cysteine thiols and that activation involves the formation of the disulfide bond Cys186-Cys 209 ... |
But while the research is being done, what provisions should be incorporated in the Clean Air Act of 1977 (or the Acts of 1978 through 2000, for that matter)? For research won't give us clear answers then either. What constitutes procedural rationality in such circumstances?“Reasonable men” reach “reasonable” conclusio... | Research on representation as congruence has reached a point of diminishing learning. Three criticisms of congruence or mandatory politics are reviewed. Representation as parallel-processing in problem-solving is introduced, defined, and illustrated by the work of the Senate Agriculture Committee. In addition to a revi... | Typical Presentation, Storyline or Metaphor Begin by asking for one or two participants to remain sighted, but speechless, and act as observers during this activity. You can provide them with optional pen and paper to take notes. For a serious corporate initiative, consider using a video camera to view the event, from ... |
This paper proposes a new approach for image encryption using a combination of different permutation techniques. The main idea behind the present work is that an image can be viewed as an arrangement of bits, pixels and blocks. The intelligible information present in an image is due to the correlations among the bits, ... | A new method for image encryption with two stages has been described in the present study. In first stage, each pixel of image is converted to its equivalent eight bit binary number and in that eight bit number, number of bits equal to the length of password are rotated and then reversed. In second stage, extended hill... | A method of analysis is presented for the class of binary sequence generators employing linear feedback shift registers with nonlinear feed-forward operations. This class is of special interest because the generators are capable of producing very long "unpredictable" sequences. The period of the sequence is determined ... |
We describe a pseudophakic patient with pseudoexfoliation who developed late intraocular lens (IOL) instability manifested by pseudophakodonesis, a change in refraction, and loss of glaucoma control. The patient subsequently required glaucoma surgery that was complicated by vitreous loss. Preoperative ultrasound biomic... | PURPOSE
To identify a delayed complication of cataract surgery in patients with zonular weakness caused by pseudoexfoliation syndrome.
DESIGN
Retrospective observational case series.
PARTICIPANTS
Eight eyes in seven patients with clinically diagnosed pseudoexfoliation syndrome who had undergone previous uncomplicat... | Abstract Multilayer heterojunction photovoltaic cells were fabricated using a solution processable pentacene derivative as the donor layer. Upon annealing of these devices, the open circuit voltage was found to gradually increase with temperature up to 265 °C. Further improvement in the photovoltaic performance was ach... |
Reliable and protected solar inverter is necessary for effective smart grid implementation. Grid fed hybrid singlestage single-phase solar inverter with incremental conductance MPPT (INC+regulator), closed loop current and voltage controller is implemented here. In normal condition inverter current T.H.D is under the l... | There are several possibilities to transfer the energy taken from a photovoltaic cell to the grid. In the past, several cell modules used the same centralized inverter to transfer the energy to the grid. Nowadays, decentralized modules are preferred because of their versatility to harvest a larger amount of power, even... | The notion of risk encompasses a wide range of meanings across different disciplines, notably the social sciences and business administration fields. Within academic finance, the focal point of traditional (or standard) finance researchers involves the objective nature of risk. This traditional finance viewpoint encomp... |
The American Association of Critical-Care Nurses (AACN) Standards for Establishing and Sustaining Healthy Work Environments and the American College of Chest Physicians (ACCP) Patient-Focused Care Project are complementary initiatives that provide a road map for creating practice environments where interdisciplinary, p... | No doubt by now, you have heard about the American Association for Critical-Care Nurses (AACN) Standards for Establishing and Sustaining Healthy Work Environments.1 In the June 2005 editorial section of Critical Care Nurse, Grif Alspach2 offers us a lifeline to achieve and sustain healthy work environments and calls on... | Background: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented. Objective: To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs. Data Sources: The MEDLINE database, conference proceeding... |
Articulatory factors underlying locus equations (LE:s) are investigated by means of an updated version of the APEX articulatory model. The modeling is focused on the determinants of LE linearity, slopes and intercepts. Linearity: For [b] and [d], linearity derives in part from acoustic mapping. In part tight linear clu... | Within the framework of refining an articulatory model, articulatory data were collected using MRI, video and X-ray. A set of two-to-three dimensional rules were derived from the axial and coronal MRI images and applied to midsagittal X-ray images. The acoustic performance of the rules was evaluated by synthesizing obs... | The shedding process of the von Karman vortices is shown to be highly related to the state of the boundary layer over the entire hydrofoil: The selected hydrofoil has a laminar-turbulent boundary layer transition at mid-chord for an incidence angle of 0° and tested Reynolds number range. With the help of a distributed ... |
The face inversion effect (FIE) is defined as the larger decrease in recognition performance for faces than for other mono-oriented objects when they are presented upside down. Behavioral studies suggest the FIE takes place at the perceptual encoding stage and is mainly due to the decrease in ability to extract relatio... | The concept of holistic processing is a cornerstone of face-recognition research. In the study reported here, we demonstrated that holistic processing predicts face-recognition abilities on the Cambridge Face Memory Test and on a perceptual face-identification task. Our findings validate a large body of work that relie... | Ear detection from a profile face image is an important step in many applications including biometric recognition. But accurate and rapid detection of the ear for real-time applications is a challenging task, particularly in the presence of occlusions. In this work, a cascaded AdaBoost based ear detection approach is p... |
Reinforces the argument that strategic and competitive success demands competence at three levels: content, change and learning. Notes that to achieve this, organizations must draw on a range of generic competences and develop an appropriate mix and measure, and that if they can achieve this they can become both compet... | Contends that the E-V-R (environment-values-resources) congruence model provides an ideal framework for examining what entrepreneurs and entrepreneurial managers must achieve strategically in order to create and sustain organisational effectiveness and success. E-V-R shows how the environment is a source of opportuniti... | We consider a supplier and a customer operating under a service agreement that requires the supplier to cover the random customer demand with high probability. To fulfill the service agreement, the supplier carries a certain amount of safety stock. The customer has some bearing on its demand variability, possibly throu... |
We study microreactors with internal fields of posts as typical examples of structured microreactors to elucidate flow fields and their implications for mass transfer. Laser-induced fluorescence (LIF) visualization combined with image analysis is used to systematically quantify key features such as interfacial area, ph... | Liquid holdup and dispersion are reported for a column of 2 mm internal diameter, filled with 0.1 mm spherical particles, for multiphase flows with hydrocarbon liquid flow rates of 10–100 μL/min and nitrogen gas flow rates of 50–1000 μL/min using different tracers with varying diffusion coefficients and vapor pressures... | We report the development of a 3G microswimmer, namely, CNT-bot, capable of undergoing acid-, alkali-, magneto- and phototaxis inside acidic or alkaline baths of peroxide fuel and/or water. The use of carboxyl-functionalised multi-walled carbon nanotubes (MWCNTs) facilitated the propulsion of CNT-bots in an alkaline-wa... |
Square-wave voltage injection is an effective sensorless control method for permanent magnet synchronous motor drives to achieve zero- or low-speed operation. However, it faces great challenge in the case of rail transit application where the switching frequency is less than or equal to 500 Hz, which results in rich lo... | This paper proposes a hybrid sensorless control strategy for rail transit application employing interior permanent magnet synchronous machine (IPMSM), which works under low switching frequency. Due to a long system time delay, the convergence rate of estimated position in the sensorless dynamic region is reduced. As th... | The aim of this paper is to analyze the behavior of a sensorless control system based on a high-frequency signal injection combined with an inset permanent-magnet (PM) motor. The rotor position of a synchronous PM motor with anisotropic rotor can be detected by the control system which superimposes a high-frequency sig... |
A screen for Saccharomyces cerevisiae temperature-sensitive silencing mutants identified a strain with a point mutation in the SIR2 gene. The mutation changed Ser276 to Cys. This amino acid is in the highly conserved NAD+ binding pocket of the Sir2 family of proteins. Haploid strains of either mating type carrying the ... | Sporothrix schenckii (S. schenckii) is a dimorphic fungus that produces lymphocutaneous lesions. The signature characteristic of S. schenckii is a temperature-induced phase transition. Silent information regulator (Sir) has been proven to be involved in phenotypic switching in Saccharomyces cerevisiae (S. cerevisiae) a... | Nature 470, 359–365 (2011) In this Article, references 1,2,3 reporting an association between telomere dysfunction and mitochondrial impairment or TERT deficiency and mitochondrial impairment were inadvertently omitted. |
Our aim was to examine the association between serum dehydroepiandrosterone sulfate (DHEAS) at baseline and BMD change at the femoral neck (FN) and lumbar spine (LS) in postmenopausal women during a 15-year follow-up. All participants were from the Chingford Study. BMD at the FN and LS were measured eight times during ... | Objective Dehydroepiandrosterone sulphate (DHEA-s) is an anabolic protective hormone of importance for maintenance of health. DHEA-s levels peak in young adults and decline thereafter with age. DHEA-s has previously been shown to be lower in individuals reporting prolonged stress. This study investigates DHEA-s levels ... | In order to assess the androgenic potency of physiological plasma concentrations of the adrenal steroids dehydroepiandrosterone (DHEA) and androstenedione (delta 4-dione) in the rat prostate, these two steroids were released from Silastic tubings of appropriate length and size in castrated male rats. Implants of DHEA l... |
The field of functional neurosurgery has expanded in last decade to include newer indications, new devices, and new methods. This advancement has challenged anesthesia providers to adapt to these new requirements. This review aims to discuss the nuances and practical issues that are faced while administering anesthesia... | Abstract.The effect of stimulation frequency for pallidal deep
brain stimulation in five patients with either generalized or
segmental dystonia was evaluated three to twelve months
postoperatively via a randomized, double-blind paradigm. The
quality of life and the severity of dystonic symptoms improved
by approximatel... | Abstract Chronic high frequency (130 Hz) stimulation (HFS) of the thalamic target Vim, first used in our group in 1987 as a treatment of tremor of various origins, has been used over the last ten years in 137 patients. Since 1993, this method has been extended to two other targets (subthalamic nucleus (STN): 137 patien... |
Most cloud services are built with multi-tenancy which enables data and configuration segregation upon shared infrastructures. Each tenant essentially operates in an individual silo without interacting with other tenants. As cloud computing evolves we anticipate there will be increased need for tenants to collaborate a... | A major drawback of existing access control systems is that they have all been developed with a specific access control policy in mind. This means that all protection requirements (i.e. accesses to be allowed or denied) must be specified in terms of the policy enforced by the system. While this may be trivial for some ... | Business models have been a concept widely discussed over the last 20 years. The increasing availability of data and the growing capability to exploit them with analytics has sparked a new set of discussions, though: it is claimed that data and analytics bring to bear entirely new "data-based" or "data-driven" business... |
Intracellular free calcium concentration ([Ca2+]i) was measured in cultured explants of myenteric plexus neurones by using the fluorescent calcium indicator Indol in combination with patch-clamp techniques. The basal [Ca2+]i was 94 nM and spontaneous oscillations in the internal free calcium concentration were recorded... | The enteric nervous system (ENS) can control gastrointestinal function independent of direct connections with the central nervous system. Enteric nerves perform this important function using multiple mechanisms of excitatory neurotransmission in enteric ganglia. Fast excitatory synaptic transmission in the autonomic ne... | In this thesis, we study the problem of network implementable controllers for network distributed systems. Network distributed control problem gains importance by the increase in networked system applications in many areas which require network distributed control and estimation. By network implementable controller, we... |
Abstract The occurrence of atypical mandibular deformities in a 17-year-old girl and her 50-year-old mother is described. Physical examination revealed multiple neurofibromatosis in both patients. Since there were no signs of neurofibromatous tumor growth in the surrounding tissues, the mandibular deformities must have... | In classical Von Recklinghausen neurofibromatosis (Type I), skeletal defects occur as a result of abnormalities of derivatives of the neuroectoderm and mesoderm. Temporomandibular joint (TMJ) disorders caused by neurofibroma in the joint capsule or disc have not been reported previously in the English language literatu... | Abstract:To present and define diagnostic criteria for primary cutaneous carcinosarcomas (CSs). Neoplasms of 6 patients with primary cutaneous CSs were retrospectively analyzed. A panel of histopathologic parameters and immunophenotypic expression of distinct markers of differentiation were investigated. All cases had ... |
Researchers in the database community have aroused great interest in handling high dimensional data sets for the past decades. Today's business captures inundate sets of data which includes digital documents, web pages-customer databases, hyper-spectral imagery, social networks, gene arrays, proteomics data, neurobiolo... | Missing Data imputation is an important research topic in data mining. In general, real data contains missing values. The presence of the missing value in the data set has a major problem for precise prediction. The objective of this paper is to highlight possible improvement of existing algorithm for medical data. KNB... | Abstract Anandite, a trioctahedral mica, has an ideal chemical formula of Ba(FeMg)3(SiFe3+)O10(OH)S and a microprobe-derived formula of (Ba0.96K0.03Na0.01)Σ=1.00(Fe2+2.01Mg0.46Fe3+0.28Al0.10Mn3+0.04Mn2+0.04 Ti0.01)Σ=2.93(Si2.60Fe3+1.40)Σ=4.00O10[(OH)0.96S0.84Cl0.16F0.04]Σ=2.00, where S2- primarily substitutes for (OH)-... |
QT interval on the surface electrocardiogram (ECG) reflects the time for repolarization of myocardium and prolongation of QTc is strongly associated with sudden cardiac death. Studies using novel techniques on beat-to-beat QT interval variability (QTV) have shown that it is influenced by the autonomic nervous system an... | BACKGROUND
Certain genetic mutations associated with hypertrophic cardiomyopathy (HCM) carry an increased risk of sudden death. QT variability identifies patients at a high risk for sudden death from ventricular arrhythmias. We tested whether patients with HCM caused by beta-myosin heavy-chain (beta-MHC) gene mutations... | Objective To assess cervical cancer prevalence and associated mortality in Grenada, West Indies during 2000-2010. Methods Records of visits to hospital and clinical facilities were obtained from the histopathology laboratory of the Grenada General Hospital. Records were de-identified and electronically compiled. Cervic... |
We consider binary abelian codes of length $p^m q^n$, where $p$ and $q$ are prime rational integers under some restrictive hypotheses. In this case, we determine the idempotents generating minimal codes and either the respective weights or bounds of these weights. We give examples showing that these bounds are attained... | Group algebras have been used in the context of Coding Theory since the beginning of the latter, but not in its full power. The article of Ferraz and Polcino Milies entitled Idempotents in group algebras and minimal abelian codes (Finite Fields Appl 13(2):382–393, 2007) gave origin to many thesis and papers linking the... | In the figure above, AA′ is a side of a 2-gon circumscribed about the circle. CC ′ is a side of a 2-gon, BC and B′C ′ are half of such sides. Consider the segment ABM. You want to prove that segment(BCM) < 1 2 segment(ABM). To this end, compare the triangles ABC and BCM ; note that they have the same height above AM . ... |
Pulmonary arterial hypertension (PAH) is a well recognized, albeit uncommon, complication of systemic lupus erythematosus (SLE) and is characterized histologically by the presence of onionskin thickening of small arterioles. We described a 24 year-old female with SLE, complicated by pulmonary hypertension after a six-w... | A lung biopsy specimen from a young woman with the clinical features of primary pulmonary hypertension showed grade 2 plexogenic pulmonary arteriopathy. Electron microscopy revealed ‘dark’, electron‐dense smooth muscle cells in the inner part of the media of muscular pulmonary arteries. Many of these transformed myocyt... | Aims: The aim of this study was to enrich, characterize and identify strict anaerobic extreme thermophilic hydrogen (H2) producers from digested household solid wastes. |
An equilateral hyperbolic zone plate has been recorded by coherent superimposition of two cylindrical waves with coplanar foci. This zone plate has been used to align quickly and easily a Mach-Zehnder interferometer. | We are about to introduce a phase shifted orthogonal zone plate that is a special kind of orthogonal zone plate in which its phase profile is transversely and equally shifted along horizontal and vertical directions. It is demonstrated that the phase shift causes the focal spot to be split into four completely identica... | This paper is an overview of what we know about occurrence of wood decay above ground within buildings. It presents information concerning under what conditions decay may become established. In laboratory tests involving optimum moisture and temperature conditions for decay fungi, and direct contact with large quantiti... |
Fiber Bragg grating sensors demonstrate a great potential as a structural health monitoring tool for civil structures to ensure structural integrity, durability, and reliability. The advantages of applying fiber optic sensors to a tall building include their immunity to electromagnetic interference and their multiplexi... | Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability to stand explosion, immunity to electromagnetic interference and high accuracy, especially fit for measurement applications in harsh environment. In this study, a nove1 FBC (filter Bragg... | In this paper, we study the statistical distribution of the accumulated polarization-dependent loss (PDL) in a recirculating loop. The distribution is studied both via numerical simulations and with analytical theory and very good agreement is found between the two. In addition, we have experimentally obtained the prob... |
We show that a suitably chosen position-momentum commutator can elegantly describe many features of gravity, including the IR/UV correspondence and dimensional reduction ("holography"). Using the most simplistic example based on dimensional analysis of black holes, we construct a commutator which qualitatively exhibits... | We argue that the minimal length discretization generalizing the Heisenberg uncertainty principle, in which the gravitational impacts on the non–commutation relations are thoughtfully taken into account, radically modifies the spacetime geometry. The resulting metric tensor and geodesic equation combine the general rel... | Abstract This paper studies how various organizational forms compare in their capacities to solve coordination problems created by technological interdependence between firms' divisions. I contrast the organizational mechanisms used by two firms, IBM and General Motors, to address these problems. While it is widely rec... |
The heat resistance of two strains of Listeria monocytogenes in sous-vide cooked fillets of cod and salmon was investigated. Fish sticks of 5 g were inoculated, vacuum-packed and heated at different combinations of time and temperature (58-80 degrees C). Time-temperature combinations allowing survival and time-temperat... | Rates of thermal inactivation of a five-strain mixture of Listeria monocytogenes were determined in ground beef roast and fermented beaker sausage. Studies were also done on ground beef contaminated with L. monocytogenes Scott A from an experimentally infected cow. D-values for the five-strain mixture at 54.4, 57.2, 60... | Scutellaria baicalensis Georgi (SBG), commonly named Huangqin, showed strong in vitro antimicrobial effects. However, limited research is available to systematically evaluate the effects of extraction methods on the phytochemical composition of SBG and its associated antimicrobial effects. In addition, limited studies ... |
BackgroundLaparoscopic appendectomy (LA) has obtained wide acceptance over the last two decades. However, some studies suggest that there is an increased rate of intraabdominal abscess (IAA) when is compared with open appendectomy. Since postoperative IAA is associated with high morbidity, identifying predictive factor... | Abstract Aim: To determine and define the advantages of the laparoscopic appendectomy in the treatment of complicated appendicitis by comparing it with the open appendectomy. Material and Methods: In this prospective interventional clinical study we compared the intraoperative data and the postoperative outcome of 77 p... | BACKGROUND: A new underbody forced-air warming system is available for use during cardiac surgery. We tested the hypothesis combining underbody forced-air warming with standard thermal management would maintain intraoperative core temperature and reduce core temperature after-drop (largest decrease in core temperature ... |
Comprehensive comparison of continuous and discontinuous Current Source Drivers (CSDs) are presented in terms of switching loss reduction and optimal design for MHz boost PFC converters. The advantages and disadvantages of the continuous and discontinuous CSDs are summarized based on the analysis and experimental resul... | In this paper state space modeling and closed loop controlled operation have been presented for primary parallel isolated boost converter (PPIBC) topology as a battery charging unit. Parasitic resistances have been included to have an accurate dynamic model. The accuracy of the model has been tested by comparing the ca... | Visual imagery during sleep has long been a topic of persistent speculation, but its private nature has hampered objective analysis. Here we present a neural decoding approach in which machine-learning models predict the contents of visual imagery during the sleep-onset period, given measured brain activity, by discove... |
The catalytic and durable electrode coating of ruthenium dioxide (RuO2), applied on nickel (Ni) substrates, is today utilized as electrocatalytic cathodes for hydrogen production, e.g., in the chlor-alkali process and alkaline water electrolysis. The drawback is, however, the sensitivity to reverse currents obtained du... | Ruthenium, iridium, and mixed ruthenium/iridium oxide layers on titanium substrates have been obtained by thermal decomposition of chloride solutions. The decomposition temperature of RuO 2 and IrO 2 was varied from 300 to 500°C and from 400 to 500°C, respectively. That on the mixed Ru x Ir 1-x 0 2 layer was kept const... | Bamboo has received increasing attention as an alternative raw material for use in the manufacture of composite boards. Random strandboards were made using a moso bamboo (Pyllostachys pubescent Mezel) strand to evaluate the effects of manufacturing parameters. Bamboo random strandboards were fabricated using phenol-for... |
Chitosan (CS)-polyvinyl alcohol (PVA) blend hydrogels were prepared using glutaraldehyde as the cross-linking agent. The obtained hydrogels, which have the advantages of both PVA and CS, can be used as a material for the transdermal drug delivery (TDD) of insulin. The nano-insulin-loaded hydrogels were prepared under t... | Abstract Background: Type 2 diabetes mellitus (DM) is characterized by insulin resistance and insulin deficiency. The majority of patients with type 2 DM will eventually require insulin therapy. The traditional paradigm for starting insulin has been to use it after therapy with oral antidiabetic agents has failed. Howe... | Abstract The EU Renewable Energy Directive (RES-Directive) establishes a policy framework for the promotion of renewable energy in the EU. Under the framework of the RES-Directive, EU Member States have adopted national renewable energy action plans including sectorial targets for electricity, heating and cooling, and ... |
A novel Clostridium sp. strain WST isolated from mangrove sediments demonstrated its unique characteristics of producing high titer of biobutanol from low concentration of substrates via anaerobic fermentation. The strain is able to convert glucose and galactose to high amount of biobutanol up to 16.62 and 12.11 g/L, r... | ABSTRACT Cellulose and hemicellulose constitute the major components in sustainable feedstocks which could be used as substrates for biofuel generation. However, following hydrolysis to monomer sugars, the solventogenic Clostridium will preferentially consume glucose due to transcriptional repression of xylose utilizat... | Three inner-city neighborhoods in varying stages of racial change were surveyed. Contrary to previous studies, it was found that the Negro ghetto exhibited lower anomie that two other areas which were undergoing racial transition. It is suggested that the pattern of social organization of the ghetto may foster a normat... |
Main conclusionThis study showed that a galactosyltransferase, AgUCGalT1, is involved in anthocyanin galactosylation in purple celery.Celery is a well-known vegetable because of its rich nutrients, low calories, and medicinal values. Its petioles and leaf blades are the main organs acting as nutrient sources. UDP-galac... | Insertion of a nonfunctional DcMYB7 duplication or transposons into the promoter region of DcMYB7 in nonpurple carrots blocks anthocyanin biosynthesis and modification. The original domesticated carrots (Daucus carota) are thought to have been purple, accumulating large quantities of anthocyanins in their roots. A quan... | Drosophila suzukii is native to East Asia and an invasive pest of fruit crops widely established in the Americas and Europe. The lack of effective indigenous parasitoids of D. suzukii in the invaded regions prompted surveys for co-evolved parasitoids in Yunnan Province, China, from 2013 to 2016. From banana-baited trap... |
This paper presents an evaluation of driving attentiveness by using Fuzzy Inference based on the driver's gaze when driving. Two cameras are used respectively to capture images in front of the driving car and to capture images of the driver's face in order to calculate the coordinates of the objects in front of the car... | There is considerable interest in unobtrusive and portable methods of monitoring sleepiness outside the laboratory setting. This study evaluates the usefulness of combined electrocardiogram (ECG) and photoplethysmogram (PPG) measurements for estimating psychomotor vigilance. The psychomotor vigilance test (PVT) was per... | This research work proposes three main contributions on the load forecasting field: the enhancement of the forecasting accuracy, the enhancement of the model adaptiveness, and the automatization on the execution of the load forecasting strategies implemented. On behalf the accuracy contribution, learning algorithms hav... |
ObjectiveTo find the effect of zinc supplementation on the outcome of neonatal sepsis at one month of age.MethodsThis randomized controlled trial was conducted in a tertiary care neonatal unit, enrolling neonates with clinical features of sepsis and positive blood culture or positive sepsis screening tests. The treatme... | During recent years, we have witnessed a growing appreciation of several micronutrients in the immune response, including vitamins and minerals [...]. | The performance of pilot scale combined process of fluidized biofilm process, chemical coagulation and electrochemical oxidation for textile wastewater treatment was studied. In order to enhance biological treatment efficiency, two species of microbes, which can degrade textile wastewater pollutants efficiently, were i... |
THE decomposition of the alkyl nitrates is chemically complex, and studies of the spontaneous ignition of methyl and ethyl nitrates have shown that this complexity is associated with a variety of visually distinct modes of inflammation. Thus methyl nitrate1–3 may undergo three different modes of decomposition : (1) slo... | Chemiluminescence has been observed in the decomposition of methyl and ethyl nitrites. Their decomposition has been investigated in the temperature range 290 to 400° C and the critical pressure limit measured above which the luminescence accompanies decomposition. The properties of this luminescent mode have been estab... | Kramer and other workers have found that freshly abraded metal surfaces produced counts when placed beneath open Geiger-Müller tubes. It has also been shown that such surfaces give photo-electrons at wavelengths longer than the photo-electric threshold of the metal. The latter effect was investigated in the present wor... |
The scientific value of citizen-science programs is limited when the data gathered are inconsistent, erroneous, or otherwise unusable. Long-term monitoring studies, such as Our Project In Hawai’i’s Intertidal (OPIHI), have clear and consistent procedures and are thus a good model for evaluating the quality of participa... | Many publications documenting large-scale trends in the distribution of species make use of opportunistic citizen data, that is, observations of species collected without standardized field protocol and without explicit sampling design. It is a challenge to achieve reliable estimates of distribution trends from them, b... | Bioremediation play key role in the treatment of petroleum hydrocarbon contaminated environment. Exposure of petroleum hydrocarbon into the environment occurs either due to human activities or accidentally and cause environmental pollution. Petroleum hydrocarbon cause many toxic compounds which are potent immunotoxican... |
A new quaternion-based method for the SINS/SAR (strap-down inertial navigation system/synthetic aperture radar) integrated navigation system is presented. This method overcomes the shortcomings due to the linear SINS error model used in the currently existing SINS/SAR integrated navigation systems. A quaternion-based m... | Multisensor navigation data synthesis (MNDS) is the process of fusing outputs from inertial sensors with information from other sensors and information processing blocks into one representational form. This technique is anticipated to accomplish enhanced accuracy and more specific inferences than could be achieved by t... | Fuel cells are an important source of renewable energy technology and currently the subject of much research. Hydrogen gas, which is the main fuel source in fuel cells, is relatively easily available, and the exhaust does not consist of greenhouse gases, unlike fossil fuel-based power sources. Some of the challenges pe... |
The composition of the products of the oxymercuration-demercuration reaction of car-3-ene according to the degree of its transformation has been studied. It has been established that this reaction forms trans-caran-3-ol, α-terpineol, m-menth-6-en-8-ol, 3,4-epoxy-trans-carane, p- and m-1, 8-cineoles, p- and m-1,8-terpin... | Die photosensibilisierte O2-Ubertragung auf (+)-Caren-(3) (1) fuhrt, nach Reduktion der dabei gebildeten Hydroperoxyde, zu drei optisch aktiven Allylalkoholen: ()-Caren-(2)-trans-ol-(4) (2), (+)-Caren-(4)-trans-ol-(3) (3) und ()-Caren-[4(10)]-trans-ol-(3) (4) im Verhaltnis von etwa 2:1:1. – Ebenso wie beim α-Pinen erfo... | The effects of osmolytes, including dimethysulfoxide, sucrose, glycine and proline, on the unfolding and inactivation of guanidine-denatured creatine kinase were studied by observing the fluorescence emission spectra, the CD spectra and the inactivation of enzymatic activity. The results showed that low concentrations ... |
This paper offers a systematic analysis of the likely economic effectsof oil and gas production and management on the Ghanaian economy. Thepaper has been motivated by the fact that some empirical literature reportthat natural resource endowment has not necessarily led to economicdevelopment in many countries. It is wit... | Abundance of oil in the GCC has provided countries within the region with large amount of wealth. This has enabled countries in the GCC to achieve economic progress, especially in the 21st century. As one of the oil rich countries in the GCC, Oman has been economically dependent on oil and gas as a major source of its ... | Ecological compensation mechanism is an important way for dealing with the conflict between environmental protection and economic development,and ensuring the social justice in the environmental sector. According to comparative analysis,it points out that ecological compensation mechanisms in developed countries are ba... |
The majority of women will experience some or most of the menopause symptoms in their life. Thais time in women’s life is associated with a reduction in estrogen levels which leads to physiological changes that affect different organ systems. In the urogenital tract, these changes usually cause vulvar and vaginal atrop... | Vaginal health, defined as the vaginal state in which the physiological condition remains stable, being protected from the onset of symptoms and facilitating a satisfying sex life, is one of the most common and less valued concerns in postmenopausal women. Many of the conditions that affect the vagina are related to it... | A novel ring-based triple-push voltage-controlled oscillator (VCO) with a continuous range from 0.2 to 34 GHz is proposed and realized using a commercial 0.13-μm 1P8M CMOS process. The output power of the VCO is −18 dBm with only ±2 dB variation in the full band. The fundamental rejection is more than 15 dB, and the se... |
Abstract A national survey asked 323 U.S. adults about paralinguistic digital affordances (PDAs) and how these forms of lightweight feedback within social media were associated with their perceived social support. People perceived PDAs (e.g., Likes, Favorites, and Upvotes) as socially supportive both quantitatively and... | This study investigated the relationships between self-disclosure in ICQ ("I seek you") chat, level of loneliness, and ICQ usage. The Revised UCLA Loneliness Scale and the Revised Self-Disclosure Scale (RSDS) were administered to a multistaged stratified random sample of 576 college students. The results indicate that ... | In the following paper, we present an approach for fine-grained recognition based on a new part detection method. In particular, we propose a nonparametric label transfer technique which transfers part constellations from objects with similar global shapes. The possibility for transferring part annotations to unseen im... |
The emissions of NO_x (defined as NO (nitric oxide) + NO_2 (nitrogen dioxide)) and hydrogen cyanide (HCN), per unit amount of fuel burned, from fires in the pine forests that dominate the mountains surrounding Mexico City (MC) are about 2 times higher than normally observed for forest burning. The ammonia (NH_3) emissi... | Evolution of anthropogenic pollution at the top of the regional mixed layer in the central Mexico plateau D. Baumgardner, M. Grutter, J. Allan, C. Ochoa, B. Rappenglueck, L. M. Russell, and P. Arnott Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Mexico City, Mexico School of Earth, Atmosp... | The term \closed form" is one of those mathematical notions that is commonplace, yet virtually devoid of rigor. And, there is disagreement even on the intuitive side; for example, most everyone would say that + log 2 is a closed form, but some of us would think that the Euler constant is not closed. Like others before ... |
Genetic diversity for micronutrient efficiency among the most highly adapted and advanced hexaploid and tetraploid wheat cultivars in the world is limited compared with alien species of wheat or rye. Therefore, screening for zinc efficiency was conducted in greenhouse experiments under controlled conditions, and in fie... | The domestication of wheat in the Fertile Crescent 10,000 years ago led to a genetic bottleneck. Modern agriculture has further narrowed the genetic base by introducing extreme levels of uniformity on a vast spatial and temporal scale. This reduction in genetic complexity renders the crop vulnerable to new and emerging... | Foods derived form plants are poorer sources of Zn for humans and monogastric animals when compared to those from animals because they can contain substances which interfere with the absorption and/or utilization (i.e., bioavailability) of Zn. Examples of these substances include phytic acid and certain types of fibre,... |
Editor The development of psoriasis, a common, chronic inflammatory skin disease, significantly depends on interleukin (IL)-17. Anti-IL-17 inhibitors, such as ixekizumab (anti-IL-17A antibody), secukinumab (anti-IL-17A antibody) and brodalumab (anti-IL-17 receptor A (IL-17RA) antibody), exert excellent therapeutic effe... | Biologics show great efficacy in treating psoriasis, a chronic inflammatory skin disease. The high cost and side‐effects of biologics, dose‐reduction, elongation of administration interval and suspension are possible options. However, there has been no reliable biomarker we can use when we consider these moderations in... | BACKGROUND
Atopic dermatitis (AD) is a common disease with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in the lack of specific treatments. AD is currently considered a biphasic disease, with T(H)2 predominating in acute disease and a switch to T(H)1 characterizing chron... |
Mutations in DJ-1/PARK7 (Parkinson protein 7) have been identified as a cause of autosomal-recessive PD (Parkinson's disease) and the antioxidant property of DJ-1 has been shown to be involved in the regulation of mitochondrial function and neuronal cell survival. In the present study, we first found that the DJ-1 tran... | The formation of cysteine-sulfinic acid has recently become appreciated as a modification that links protein function to cellular oxidative status. Human DJ-1, a protein associated with inherited parkinsonism, readily forms cysteine-sulfinic acid at a conserved cysteine residue (Cys106 in human DJ-1). Mutation of Cys10... | Contrary to the response of rats of the highly sensitive inbred strain BDIX, BDIV rats are resistant to the induction of malignant schwannomas by exposure to the alkylating N-nitroso carcinogen N-ethyl-N-nitrosourea (EtNU). In BDIX rats, a point mutation at nucleotide 2012 in the transmembrane region of the neu/erbB-2 ... |
A new method for mutation detection is described, which is a technical advancement of the protein truncation test. The new technique is non‐radioactive and highly sensitive for detection of virtually all sequence mutations, which lead to a stop signal or to the shift of the translation frame. The method includes four s... | The protein truncation test is a useful method for identifying frameshift and nonsense mutations. The interpretation of real results is often made difficult by the presence of internally translated protein products and other nonspecific bands. To overcome these problems, the technique has been modified to include a myc... | It is difficult to quantify the amount of groundwater inflow on the Tibetan Plateau (TP), yet it can be critically important for sustaining lake water balance. Here we show that most endorheic lakes on the western TP exhibited considerable water level increase during the ice‐covered period, which contrasts with lakes i... |
There has been an increasing interest in kernel-based techniques, such as support vector techniques, regularization networks, and gaussian processes. There are inner relationships among those techniques, with the kernel function playing a central role. This article discusses a new class of kernel functions derived from... | Wireless sensor networks are often studied with the goal of removing information from the network as efficiently as possible. However, when the application also includes an actuator network, it is advantageous to determine actions in-network. In such settings, optimizing the sensor node behavior with respect to sensor ... | This paper considers the classical semiparametric partially linear model with exact inputs and interval-valued fuzzy outputs. For this purpose, the most commonly used classical two-phase procedure is extended to estimate an interval-valued fuzzy smooth function using nonparametric kernel methods at phase 1 and a least ... |
Recent work in machine learning and natural language processing has studied the health content of tweets and demonstrated the potential for extracting useful public health information from their aggregation. This article examines the types of health topics discussed on Twitter, and how tweets can both augment existing ... | null | null |
Generalizing the probabilistic correlation ratio we will introduce a correlation ratio for marginal possibility distributions of joint possibility distributions. | Carlsson and Fuller introduced the notions of possibilistic mean value and variance of fuzzy numbers. Fuller and Majlender introduced a measure of possibilistic covariance between marginal distributions of a joint possibility distribution as the average value of the interactivity relation between the level sets of its ... | Abstract Starting from a subjective assignation of weights related to the relative importance of the different level sets, we define a new method of comparison of fuzzy numbers. This procedure is an extension of some well-known indices (Adamo, Tsumura et al., Yager). Some properties of our index are studied in this pap... |
Abstract A major project in rural planning and development was initiated in the eastern counties of Washington (State) beginning in 1976. The purpose was to merge several previous ‘model’ within a new conceptual framework incorporating collaboration among diverse organizations as a means of integrating development acti... | Seventy per cent of the world poor population lives in rural areas. Despite efforts to eradicate poverty, results are limited. Rural development is a process to transform production and change institutions; but psychosocial obstacles exist. Our aim was to explore and describe the synergy of rural development and Psycho... | This baseline study used data from a informant survey of 76 rural communities in Central Tunisia to construct, first, measures of rural poverty and ecological deterioration and, second, indices of the major institutional complexes in the region. Using factor analysis, the study identified five institutional dimensions:... |
The conventional understanding that a bandstructure that produces a Dirac delta function transport distribution (or transmission in the Landauer framework) maximizes the thermoelectric figure of merit, ZT, is revisited. Thermoelectric (TE) performance is evaluated using a simple tight binding (TB) model for electron di... | Solid-state thermoelectric devices are currently used in applications ranging from thermocouple sensors to power generators in space missions, to portable air-conditioners and refrigerators. With the ever-rising demand throughout the world for energy consumption and CO2 reduction, thermoelectric energy conversion has b... | Abstract Electrical and thermal properties of rectangular quantum wires of polycrystalline bismuth telluride have been investigated in the framework of the relaxation time approximation. Electrical conductivity, electronic thermal conductivity and thermopower have been obtained in the temperature range 200–600 K for tw... |
The N-acetylcystamine (SNAC) thioester of dodecapentaenoic acid, an analog of a putative intermediate in the biosynthesis of Heat Stable Antifungal Factor (HSAF), is synthesized. Key steps include sequential Horner-Emmons homologations with the Weinreb amide of diethylphosponoacetic acid, and thioesterification of an a... | BackgroundThe environmental gliding bacteria Lysobacter are emerging as a new group of biocontrol agents due to their prolific production of lytic enzymes and potent antibiotic natural products. These bacteria are intrinsically resistant to many antibiotics, but the mechanisms behind the antibiotic resistance have not ... | Rb+ uptake into protoplasts isolated from the mesophyll of Pisum sativum L. cv. Dan has been followed at intervals of a few minutes in the light and in the dark. The progress curve for uptake in the dark decreased in slope after about 7 min; in the light, by contrast, the slope increased. This effect was more pronounce... |
Synopsis This research is part of the NIMH-CRB Collaborative Study on the psychobiology of depression. The main objective of the research programme is to test hypotheses concerning the interaction of neurobiological mechanisms and behaviour in the depressive disorders. Part I of the report describes the rationale and t... | In a prior study, we identified factors of psychopathology in the interview, ward behavior and self-report ratings of 124 depressed patients from 9 hospitals. The present study attempts to replicate these findings in a sample of 648 depressed patients from 10 hospitals. The criteria for patient selection and the factor... | Despite of numerous publications in sunflower genetic transformation, there is no efficient or reproducible protocol with low number of escapes. The latter would indicate that the selection method is not effective. In this work we used Km as selective agent, Agrobacterium tumefaciens EHA105 strain and a vector with the... |
Traditional object oriented analysis methodolo-gies are based not only upon objects, but also upon relationships between objects. Object oriented programming languages do not provide support for relationships, and so analysis relationships must be expressed indirectly within a program's design, and then incorporated in... | In this paper we investigate the addition of first-class relationships to a prototypical object-oriented programming language (a “middleweight” fragment of Java). We provide language-level constructs to declare relationships between classes and to manipulate relationship instances. We allow relationships to have attrib... | A constraint describes a relationship that should be maintained, for example that the equality A + B = C holds between three variables, that a set of displayed objects are aligned, or that the elements in a data structure are consistent with a graphic display of this structure. Constraint solvers have been successfully... |
OBJECTIVE
To determine the pathological, clinical, and therapeutic factors which had prognostic significance in women with extraovarian primary peritoneal carcinoma (EOPPC).
METHODS
A retrospective, clinicopathologic study was conducted of 75 women diagnosed with EOPPC. Diagnosis and assessment of prognostic patholog... | A 69-year-old woman who presented with left lower quadrant abdominal pain and elevated serum cancer antigen 125 (CA-125) levels was referred for an MRI and an 18F-FDG PET/CT to evaluate a suspicious abdominal mass seen on ultrasound. PET/CT showed extensive, intensely FDG-avid, omental and pelvic peritoneal thickening ... | We describe a retroperitoneal neoplasm in an 11-year-old girl which had a light microscopic appearance identical to that of papillary serous carcinoma of the ovary. There was no evidence of ovarian involvement. Immunohistochemical staining for amylase was positive within the cytoplasm of tumor cells. Since amylase is a... |
Polymerase chain reaction (PCR) testing is the gold standard for determining the HIV status in children <18 months of age. However, when clinical manifestations are not consistent with laboratory results, additional investigation is required. We report a 15-month-old HIV-exposed boy referred to our hospital after he ha... | The HIV p24 capsid protein has an essential, structural, and functional role in the viral replication cycle, being an interesting target for vaccine design, diagnostic tests, and new antiretroviral drugs (ARVs). The HIV-1 variability poses a challenge for the accuracy and efficiency of diagnostic and treatment tools. T... | The polymerase chain reaction (PCR), using primer pairs in the gag, pol, and env regions, was used in a comparative study of HIV-1 DNA in peripheral mononuclear blood cells from HIV-1-seropositive individuals in Ethiopia and Sweden. Although all Swedish samples were positive by PCR, the reactivity was more pronounced i... |
This study examines associations between social capital and health outcomes with data from the 2010 Brazos Valley Health Survey (Texas) (N = 3,176). Multivariate adjusted logistic regression analysis demonstrated that poor and fair health status was inversely predicted by both high trust (adjusted OR = .67 [CI = .50–.9... | This study examined associations between self-rated health and combinations of social participation and trust among ageing people in three living areas of Finland (N=2815, 66% response rate). Social participation and trust combinations were: low social capital (low participation/low trust), traditionalism (low/high), "... | Ultrasonography in reptiles is a safe, noninvasive repeatable diagnostic imagine method. Size, volume and inner structure of organs can easily be determined. Based on 460 ultrasonographic examinations in 8 species of terrapins, 12 species of snakes and 22 species of lizard normal appearance of heart, gonads, fat bodies... |
Binary mixtures of the ionic liquid betainium bis(trifluoromethylsulfonyl)imide and water show an upper critical solution temperature. This solvent system has been used to extract metal ions by phase-transition extraction, using zwitterionic betaine as extractant. The system is efficient for the extraction of trivalent... | In this paper new extractants, that have the potential to be sustainably regenerated, are proposed for metal removal from aqueous phases. These extractants are a novel class of ionic liquids (ILs) with unsaturated fatty acids as anions (oleate and linoleate). The advantages of using these ILs are their simple synthesis... | In some situations, it is no longer sufficient to give a total concentration of a metal. Instead, what is required to understand the potential toxicity of a sample is the concentration of metal species or oxidation state. When developing species specific methods, the major concern is that the integrity of the species r... |
Using vision systems with SCARA robotic manipulators is beneficial in many industrial applications specially in automated object picking and placing tasks. In this paper, the equations of forward and inverse kinematics of a SCARA manipulator are derived using D-H parameters convention. The mechanical structure, as well... | This paper focuses on modeling resolving and simulations of the inverse kinematics of an anthropomorphic redundant robotic structure with seven degrees of freedom and a workspace similar to human arm. Also the kinematical model and the kinematics equations of the robotic arm are presented. A method of resolving the red... | Metro maps are schematic diagrams of public transport networks that serve as visual aids for route planning and navigation tasks. It is a challenging problem in network visualization to automatically draw appealing metro maps. There are two aspects to this problem that depend on each other: the layout problem of findin... |
Population regulation is a central concept in ecology, yet in many cases its presence and the underlying mechanisms are difficult to demonstrate. The current paradigm maintains that marine fish populations are predominantly regulated by density-dependent recruitment. While it is known that density-dependent somatic gro... |
During the 20th century, many large-bodied fish stocks suffered from unsustainable fishing pressure. Now, signs of recovery are appearing among previously overfished large-bodied fish stocks. This new situation raises the question of whether current fisheries advice and management procedures, which were devised and o... | Vattern, the second largest lake of Sweden, contains 28 species of fish, of which Arctic char (Salvelinus alpinus) and whitefish (Coregonus spp.) are the most important economically. There is both a commercial fishery and a sport fishery. The former has decreased steadily, while the latter is increasing. A modest eutro... |
This paper presents a real case study on the testing of 8-bit mixed-signal CMOS micro-controller devices by applying the IDDQ testing methodology. The aim of the study is to evaluate the feasibility of using the IDDQ test to enhance the overall fault coverage. Failure analysis operated on the failed sample indicated a ... | The SEMATECH "Test Methods Evaluation" study, Project Number S-121, is an experiment to determine the relative merits of several test methodologies often used by SEMATECH member companies and other IC manufacturers. Conclusions drawn from the experiment thus far have indicated that each test methodology uniquely detect... | Reverse osmosis and electrodialysis are truly the only water desalination processes currently in practice for the entire range of total dissolved solids (TDS) from 400–40,000 mg/L. For high recovery of 80% or more, membrane processes are energy intensive even for a feedwater with a TDS of 1000 mg/L and demand significa... |
A predictive model was satisfactorily developed to describe the general trends of product distribution in fluidized beds of lignocellulosic biomass pyrolysis. The model was made of mass balance based on proximate analysis and an empirical relationship with operating parameters including fluidization hydrodynamics. The ... | Owing to its low cost and large availability, lignocellulosic biomass is being studied worldwide as a feedstock for renewable liquid biofuels. Lignocellulosic biomass is not currently used as a liquid fuel because economical processes for its conversion have not yet been developed. Currently, there are several routes b... | This work presents an integrated approach for the design of diesel hydrotreating processes employing a simulated annealing optimisation algorithm. The modelling of reactor, separation and heat recovery system for diesel hydrotreating processes is discussed, and a novel optimisation framework is developed for the design... |
Two different models are presented and developed in PSCAD/EMTDC to represent a variable-speed wind turbine equipped with a doubly fed induction generator (DFIG). One is the most detailed switching-level (SL) model. The other is a simplified fundamental-frequency (FF) model. The effect of different shaft system represen... | This paper reviews the power electronic applications for wind energy systems. Various wind turbine systems with different generators and power electronic converters are described, and different technical features are compared. The electrical topologies of wind farms with different wind turbines are summarized and the p... | We introduce a new method to grade non-native spoken language tests automatically. Traditional automated response grading approaches use manually engineered time-aggregated features (such as mean length of pauses). We propose to incorporate general time-sequence features (such as pitch) which preserve more information ... |
As inflammation emerges as a risk factor for prostate cancer (PCa), there is potential for chemoprevention by anti-inflammatory agents. Dietary phytochemicals have been shown to have chemopreventive properties which may include anti-inflammatory activities. In this study, we demonstrate a role for mitogen-activated pro... | Background: Laboratory and epidemiologic studies suggest that aspirin and nonaspirin nonsteroidal anti-inflammatory drugs (NSAID) reduce the risk of cancer, possibly via inhibition of the cyclooxygenase enzymes. We evaluated the association of aspirin and nonaspirin NSAIDs with subsequent prostate cancer in a prospecti... | The U.S. Supreme Court in McDonnell v. United States (2016) vacated the conviction of a former Virginia governor for accepting bribes. The court found that arranging a meeting, calling or contacting another official, or hosting an event does not, by itself, rise to the level of an official act under the Hobbs Act and t... |
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) transcription is essential for viral replication and the only step for viral genome amplification. Cyclin T1 (CycT1) interacts with HIV-1 Tat and transactivation-responsive (TAR) RNA, leading to the activation of viral transcription through the hyperphosphorylation o... | The regulation of transcription of the human immunodeficiency virus (HIV) is a complex event that requires the cooperative action of both viral and cellular components. In latently infected resting CD4+ T cells HIV‐1 transcription seems to be repressed by deacetylation events mediated by histone deacetylases (HDACs). U... | HIV-1 Tat binds human CyclinT1 and recruits the CDK9/P-TEFb complex to the viral TAR RNA in a step that links RNA polymerase II (RNAPII) C-terminal domain (CTD) Ser 2 phosphorylation with transcription elongation. Previous studies have suggested a connection between Tat and pre-mRNA splicing factors. Here we show that ... |
Meat quality is an important trait for the beef industry. Backfat thickness, ribeye area, and shear force are traits measured late in life, and the investigation of molecular markers associated with these traits can help breeding programs. In cattle, some polymorphisms have been related to production traits. Thus, the ... | Insulin-like growth factor-1 (IGF-1) gene plays an important role in the endocrine system of animals by regulating nutrient metabolism, growth, and milk production. There have been extensive molecular genetics research studies on cattle but less studies have focused on buffalo (Bubalus bubalis). This study aimed to con... | Nuclear factor I, a 47-kilodalton protein, purified from nuclear extracts of uninfected HeLa cells, is involved in the initiation and possibly the elongation of replicating adenovirus (Ad) DNA in vitro. The binding of nuclear factor I to DNA has been monitored by a filter binding assay of nuclear factor I to DNA has be... |
BackgroundAmong themophilic consolidated bioprocessing (CBP) candidate organisms, environmental isolates of Clostridium clariflavum have demonstrated the ability to grow on xylan, and the genome of C. clariflavum DSM 19732 has revealed a number of mechanisms that foster solubilization of hemicellulose that are distinct... | Solventogenic clostridia are native producers of ethanol and many higher alcohols employing a broad range of cheap renewable substrates, such as lignocellulosic materials and C1 gases (CO and CO2). These characteristics enable solventogenic clostridia to act as flexible microbial platforms for the production of liquid ... | In the present pharmacokinetic/pharmacodynamic (PK/PD) evaluation, cortisol, total lymphocytes, and lymphocyte subpopulations were monitored following single oral doses of two oral formulations of 3 mg budesonide (BUD) (Dosage Forms A and B) in order to assess the differential effects that BUD may have on cortisol supp... |
This article identifies the explanatory sources of Asians' perceptions about China's rise. The authors try to decipher the relative importance of individual-level explanatory variables such as socio-economic satisfaction, cognitive schema, and ideology and political values vis-à-vis that of the country-level structural... | This paper revisits the debate about foreign policy implications of Chinese nationalism in the context of China's increasingly confrontational and assertive behavior in recent years. It argues that while the Chinese government made effective efforts to control popular nationalism and Chinese foreign policy was therefor... | An extensive body of evidence has been accumulated showing that alliances are more often followed by war than by peace (Singer and Small, 1966b; Levy, 1981). It has also been convincingly demonstrated that alliances are associated with the expansion of war (Siverson and King, 1979; 1980; Siverson and Starr, 1990), and ... |
Dictyostelium amoebae have been used as a host model to measure virulence of a wide range of bacterial pathogens. The simple protocol described here takes advantage of the ability of Dictyostelium to grow and form plaques on a lawn of nonpathogenic bacteria but not on virulent bacteria. This assay can be modulated to m... | The genetic factors used for host interaction by the opportunistic human pathogen Pantoea ananatis are largely unknown. We identified two genes that are important for the production of a biosurfactant that confers grazing resistance against the social amoeba Dictyostelium discoideum. We show that the biosurfactant, whi... | Pathogenic microbes have evolved highly sophisticated mechanisms for colonizing host tissues and evading or deflecting assault by the immune response. The ability of these microbes to avoid clearance prolongs infection, thereby promoting their long-term survival within individual hosts and, through transmission, betwee... |
Providing detailed appliance level energy consumption information may lead consumers to understand their usage behavior and encourage them to optimize the energy usage. Non-intrusive load monitoring (NILM) or energy disaggregation aims to estimate appliance level energy consumption from the aggregate consumption data o... | Accurate indoor localization using minimalist hardware has a huge potential for energy savings and smart homes. Current indoor localization techniques involve deployment of complex arrays of sensors such as Bluetooth beacons, PIR sensors, etc. However, these sensors are commonly intrusive and the techniques require ext... | In 3-D applications, a high-quality depth video codec with low complexity is in great demand for consumer devices, which generally have limited computational resources and energy. Based on the compressed sensing theory, we propose a low complexity depth video codec to compress depth videos effectively. The proposed cod... |
BACKGROUND Colorectal cancer is one of the leading causes of death from cancer in Western countries. Removal of adenomas is based on the assumption that it could lead to a reduction in the incidence of colorectal cancer, as demonstrated by the National Polyp Study in the USA. A critical issue is whether the benefit obs... | This document is the first update of the American College of Gastroenterology (ACG) colorectal cancer (CRC) screening recommendations since 2000. The CRC screening tests are now grouped into cancer prevention tests and cancer detection tests. Colonoscopy every 10 years, beginning at age 50, remains the preferred CRC sc... | BACKGROUND
Antimicrobial resistance is low in Norway, but to prevent an increase, the Norwegian Government has launched a National Strategy including a 30% reduction of broad-spectrum antibiotics (BSA) in hospitals within 2020. BSA are defined as second- and third-generation cephalosporins, carbapenems, piperacillin/ta... |
The pericentromeric region of chromosome 16p is rich in segmental duplications that predispose to rearrangements through non-allelic homologous recombination. Several recurrent copy number variations have been described recently in chromosome 16p. 16p11.2 rearrangements (29.5–30.1 Mb) are associated with autism, intell... | Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by marked genetic heterogeneity. Recent studies of rare structural and sequence variants have identified hundreds of loci involved in ASD, but our knowledge of the overall genetic architecture and the underlying pathophysiological mec... | Cellular and intracellular motile events in plants are susceptible to SH reagents such as N-ethylmaleimide (NEM). It has long been believed that the target of the reagent is myosin. We compared the effect of NEM on the motile and ATPase activities of skeletal muscle myosin with that on plant myosin using characean alga... |
Although industrial sites producing perfluoroalkyl and polyfluoroalkyl substances (PFASs) may introduce these chemicals into the aquatic environment, they are rarely investigated. This study entailed measuring concentrations, mass flows and the fate of 51 PFASs in an industrial wastewater treatment plant receiving raw ... | Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are emerging contaminants that have been detected in the environment, biota, and humans. Drinking water is a route of exposure for populations consuming water contaminated by PFAS discharges. This research study reports environmental measurement concentrations, mass... | 9. SCHOU, L., BENSON, A. A., BASSHAM, J. A., and CALVIN, M. The path of carbon in photosynthesis. XI. The role of glycolic acid. Physiol. Plantarum 3: 487-495. 1950. 10. THIMANN, K. V. and BONNER, W. D., JR. Organic acid metabolism. Ann. Rev. Plant Physiol. 1: 75-108. 1950. 11. TOLBERT, N. E. and BURRIS, R. H. Light ac... |
IntroductionNon-Latina black breast cancer patients experience a shorter survival from breast cancer than their non-Latina white counterparts. We compared breast cancer-specific survival for the subset of black and white patients with estrogen and/or progesterone receptor-positive tumors that are generally targeted wit... | Breast cancer (BC) has emerged as a deadly disease that affects the lives of millions of women worldwide. It is the second leading cause of cancer-related deaths in the United States. Advancements in BC screening, preventive measures and treatment have resulted in significant decline in BC related deaths. However, unac... | BackgroundRecent studies suggest that the poorer breast cancer outcome observed in African-American women (AAW) may, in part, result from underlying molecular factors. The purpose of this study was to investigate gene expression differences between Caucasian-American women (CAW) and AAW that may contribute to this poor... |
Prolonged exposure to a stimulus results in a subsequent perceptual bias. This perceptual adaptation aftereffect occurs not only for simple stimulus features but also for high-level stimulus properties (e.g., faces’ gender, identity and emotional expressions). Recent studies on aftereffects demonstrate that adaptation ... | Repeated exposures to thin-idealized body shapes may alter women’s perceptions of what normal (e.g., accepted) and ideal (e.g., desired) bodies in a cultural environment look like. The aim of the present study was to investigate whether exposure to thin and round body shapes may change the subsequent esthetic appreciat... | Because long‐term antipsychotics elicit behavioral dopamine supersensitivity, the present study examined whether 7–9 days administration of partial dopamine D2 agonists with antipsychotic activity, bifeprunox and aripiprazole, could induce biochemical changes that suggest dopamine supersensitivity. In rats, behavioral ... |
Despite emerging evidence and guidelines, poor prescribing and administration of oxygen therapy persists. This study aimed to explore healthcare professionals’ (HCPs) and patients’ perceptions of oxygen. | Background: Chronic breathlessness syndrome in the context of advancing disease is distressing for all concerned. Oxygen is commonly prescribed in this setting; however, little is known about the perspectives of breathless people who either are on oxygen or are yet to have it prescribed. Aim: To understand and describe... | BACKGROUND
Breathlessness remains a refractory symptom in malignant lung disease. Breathing training is an effective, non-pharmacological intervention but it is unclear how this should be delivered. This feasibility study aimed to assess recruitment and retention, best end point and variability of breathlessness scores... |
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