anurag-raapid/chia · Datasets at Hugging Face

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Pregnant or lactating women. Evolutive skin disease on the testing zone (lower back). Patients with a clinically significant disease (chronic, recurrent or active). Systemic corticotherapy or immunosuppressive treatment during the previous month, or local corticoid treatment the week before the patch testing. Local or systemic drug use which interacts with the outcome measures. Exposure to sun or UV radiations, 15 days before the patch testing. Patients deprived of their civic rights, in custody, or subject to a tutorial, judiciary or administrative decision. Patients subject to a protection measure. Patients in a critical medical situation. Patients with a personal situation judged by the investigator as unlikely to be compatible with optimal participation in the study, or which could constitute a risk for the patient. Linguistic barrier or psychological profile preventing the patient from signing the consent form. Patient still in an exclusion period following the participation in another clinical trial. Patients having earned more than 4500€ in indemnities for participation in clinical trials during the previous 12 months, including this study.	[ "Pregnant", "or", "lactating", "women", ".", "\n", "Evolutive", "skin", "disease", "on", "the", "testing", "zone", "(", "lower", "back", ")", ".", "\n", "Patients", "with", "a", "clinically", "significant", "disease", "(", "chronic", ",", "recurrent", "or", ...	[ { "text": "Pregnant", "type": "Condition", "char_start": 0, "char_end": 8, "token_start": 0, "token_end": 1 }, { "text": "lactating", "type": "Condition", "char_start": 12, "char_end": 21, "token_start": 2, "token_end": 3 }, { "text": "women", "type": ...	NCT00445029_exc
For both groups: Patients aged from 18 to 65 years old. Both genders eligible for study. Female participants must use a contraceptive method. Feasibility of patch testing. Participants must be able to understand and sign the Informed Consent, and comply with all aspects of the protocol. Patients must be registered in a social security system or with a health insurance coverage  First group: allergic patients Patients with allergic contact dermatitis to para-phenylenediamine (PPD) based on a history of PPD contact dermatitis and positive PPD patch tests.  Second group : healthy volunteers No history of PPD allergic contact dermatitis, with a negative PPD patch test.	[ "For", "both", "groups", ":", "\n", "Patients", "aged", "from", "18", "to", "65", "years", "old", ".", "\n", "Both", "genders", "eligible", "for", "study", ".", "\n", "Female", "participants", "must", "use", "a", "contraceptive", "method", ".", "\n", "Fe...	[ { "text": "aged", "type": "Person", "char_start": 27, "char_end": 31, "token_start": 6, "token_end": 7 }, { "text": "from 18 to 65 years old", "type": "Value", "char_start": 32, "char_end": 55, "token_start": 7, "token_end": 13 }, { "text": "Both genders",...	NCT00445029_inc
age less than 13 years at time of procedure use of pain medication prior to procedure pectus carinatum, Poland's syndrome, or any chest wall anomaly other than pectus excavatum previous repair of pectus excavatum by any technique previous thoracic surgery congenital heart disease bleeding dyscrasia major anesthetic risk factors or history of previous problem with anesthesia pregnancy inability to communicate in English	[ "age", "less", "than", "13", "years", "at", "time", "of", "procedure", "\n", "use", "of", "pain", "medication", "prior", "to", "procedure", "\n", "pectus", "carinatum", ",", "Poland", "'s", "syndrome", ",", "or", "any", "chest", "wall", "anomaly", "other",...	[ { "text": "age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "less than 13 years", "type": "Value", "char_start": 4, "char_end": 22, "token_start": 1, "token_end": 5 }, { "text": "at time of procedure", ...	NCT02721017_exc
scheduled for Nuss procedure for pectus excavatum correction at least 13 years old at the time of the procedure	[ "scheduled", "for", "Nuss", "procedure", "for", "pectus", "excavatum", "correction", "\n", "at", "least", "13", "years", "old", "at", "the", "time", "of", "the", "procedure", "\n" ]	[ { "text": "scheduled", "type": "Mood", "char_start": 0, "char_end": 9, "token_start": 0, "token_end": 1 }, { "text": "Nuss procedure", "type": "Procedure", "char_start": 14, "char_end": 28, "token_start": 2, "token_end": 4 }, { "text": "pectus excavatum", ...	NCT02721017_inc
Any anti-coagulation therapy (apart from rivaroxaban for second objective) Hypersensitivity or allergy to factor Xa inhibitors Acute bacterial endocarditis Bleeding disorder Clinically relevant active bleeding Gastrointestinal ulcer or tumor Hepatic dysfunction with increased bleeding risk Renal failure / patients undergoing dialysis Pregnancy and breast feeding Gastrectomy, biliopancreatic diversion, resection or re-routing of small intestines Feeding tube Recent blood donation Abnormalities of laboratory values: alanine-aminotransferase (ALAT), aspartate-aminotransferase (ASAT), gamma-glutamyl transferase (gammaGT), alkalic phosphatase (AP), bilirubin, amylase, lipase, cystatin C, creatinine, white blood cell count, haemoglobin, platelet count, prothrombin time, aPTT, fibrinogen, thrombin time, factors II,V,VII and X Use of therapeutic or recreational drugs influencing plasmatic coagulation	[ "Any", "anti", "-", "coagulation", "therapy", "(", "apart", "from", "rivaroxaban", "for", "second", "objective", ")", "\n", "Hypersensitivity", "or", "allergy", "to", "factor", "Xa", "inhibitors", "\n", "Acute", "bacterial", "endocarditis", "\n", "Bleeding", "di...	[ { "text": "anti-coagulation therapy", "type": "Procedure", "char_start": 4, "char_end": 28, "token_start": 1, "token_end": 5 }, { "text": "apart from", "type": "Negation", "char_start": 30, "char_end": 40, "token_start": 6, "token_end": 8 }, { "text": "riv...	NCT02970773_exc
Motor complete tetraplegia for at least 3 months Age from 18 to 74 years Body mass index (BMI) from 18 to 35kg/m2 Informed consent as documented by signature	[ "Motor", "complete", "tetraplegia", "for", "at", "least", "3", "months", "\n", "Age", "from", "18", "to", "74", "years", "\n", "Body", "mass", "index", "(", "BMI", ")", "from", "18", "to", "35kg", "/", "m2", "\n", "Informed", "consent", "as", "document...	[ { "text": "complete", "type": "Qualifier", "char_start": 6, "char_end": 14, "token_start": 1, "token_end": 2 }, { "text": "tetraplegia", "type": "Condition", "char_start": 15, "char_end": 26, "token_start": 2, "token_end": 3 }, { "text": "at least 3 months...	NCT02970773_inc
Anaphylactic reaction to a previous dose of TIV(trivalent influenza vaccine) Known IgE( Immunoglobulin E)-mediated hypersensitivity to eggs manifested as hives, swelling of the mouth and throat, difficulty in breathing, hypotension, or shock Guillain-Barré syndrome within eight weeks of a previous influenza vaccine Anaphylactic reaction to neomycin Patients who have had influenza vaccine in two of the three previous years	[ "Anaphylactic", "reaction", "to", "a", "previous", "dose", "of", "TIV", "(", "trivalent", "influenza", "vaccine", ")", "\n", "Known", "IgE", "(", "Immunoglobulin", "E", ")", "-", "mediated", "hypersensitivity", "to", "eggs", "manifested", "as", "hives", ",", ...	[ { "text": "Anaphylactic reaction", "type": "Condition", "char_start": 0, "char_end": 21, "token_start": 0, "token_end": 2 }, { "text": "TIV", "type": "Drug", "char_start": 44, "char_end": 47, "token_start": 7, "token_end": 8 }, { "text": "trivalent influen...	NCT02762851_exc
Age = 18 years and NYHA (New York Heart Association) functional class II, III and IV	[ "Age", "=", "18", "years", "and", "NYHA", "(", "New", "York", "Heart", "Association", ")", "functional", "class", "II", ",", "III", "and", "IV", "\n" ]	[ { "text": "Age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "= 18 years", "type": "Value", "char_start": 4, "char_end": 14, "token_start": 1, "token_end": 4 }, { "text": "NYHA (New York Heart Association...	NCT02762851_inc
Currently dependent on any substance other than cannabis, alcohol or nicotine; History of any major internal disease (including diabetes, cardiovascular disease, lung disease, liver or kidney disease); An active or any history of neurological disorder, including but not limited to seizure disorder, epilepsy, stroke, neurological disease, cognitive impairment, head trauma with prolonged loss of consciousness (>10 minutes), or migraine headaches; An active or a history of a psychiatric disorder including, but not limited to, depression, schizophrenia, bipolar disorder, anxiety, or other psychiatric disorders; Asthma; Known hypersensitivity or allergy to n-acetylcysteine, or receiving chronic therapy with medication that could interact adversely with n-acetylcysteine within 30 days prior to randomization (i.e., nitroglycerin, ACE inhibitors or antihypertensive drugs, anti-coagulants); Exclusion criteria for MRI: having metal in the body and/or having claustrophobia	[ "Currently", "dependent", "on", "any", "substance", "other", "than", "cannabis", ",", "alcohol", "or", "nicotine", ";", "\n", "History", "of", "any", "major", "internal", "disease", "(", "including", "diabetes", ",", "cardiovascular", "disease", ",", "lung", "...	[ { "text": "dependent", "type": "Condition", "char_start": 10, "char_end": 19, "token_start": 1, "token_end": 2 }, { "text": "substance", "type": "Drug", "char_start": 27, "char_end": 36, "token_start": 4, "token_end": 5 }, { "text": "other than", "type...	NCT03221231_exc
Current DSM-IV diagnosis of cannabis dependence, >1 week detoxified and abstinent; Able to provide written informed consent and to comply with study procedures. Dutch speaking (Dutch as primary language).	[ "Current", "DSM", "-", "IV", "diagnosis", "of", "cannabis", "dependence", ",", ">", "1", "week", "detoxified", "and", "abstinent", ";", "\n", "Able", "to", "provide", "written", "informed", "consent", "and", "to", "comply", "with", "study", "procedures", "."...	[ { "text": "DSM-IV", "type": "Qualifier", "char_start": 8, "char_end": 14, "token_start": 1, "token_end": 4 }, { "text": "cannabis dependence", "type": "Condition", "char_start": 28, "char_end": 47, "token_start": 6, "token_end": 8 }, { "text": ">1 week", ...	NCT03221231_inc
Unable or unwilling to provide informed consent. Active ischemia (acute thrombus diagnosed by coronary angiography, or dynamic ST segment changes demonstrated on ECG) or another reversible cause of VT (e.g. drug-induced arrhythmia), had recent acute coronary syndrome within 30 days, coronary revascularization (<90 days bypass surgery, <30 days percutaneous coronary intervention), or have CCS functional class IV angina. Note that biomarker level elevation alone after ventricular arrhythmias does not denote acute coronary syndrome or active ischemia. Are ineligible to take the antiarrhythmic drug to which they would be assigned due to allergy, intolerance or contraindication Are known to have protruding left ventricular thrombus or mechanical aortic and mitral valves Have had a prior catheter ablation procedure for VT Are in renal failure (Creatinine clearance <15 mL/min), have NYHA Functional class IV heart failure, or a systemic illness likely to limit survival to <1 year Have had recent ST elevation myocardial infarction or non-ST elevation MI (< 30 days); note that biomarker elevation alone after ventricular arrhythmias does not denote MI. Are pregnant.	[ "Unable", "or", "unwilling", "to", "provide", "informed", "consent", ".", "\n", "Active", "ischemia", "(", "acute", "thrombus", "diagnosed", "by", "coronary", "angiography", ",", "or", "dynamic", "ST", "segment", "changes", "demonstrated", "on", "ECG", ")", "o...	[ { "text": "Active", "type": "Qualifier", "char_start": 49, "char_end": 55, "token_start": 9, "token_end": 10 }, { "text": "ischemia", "type": "Condition", "char_start": 56, "char_end": 64, "token_start": 10, "token_end": 11 }, { "text": "acute thrombus", ...	NCT02830360_exc
Prior Myocardial Infarction and Sustained monomorphic VT documented on 12-lead ECG or rhythm strip terminated by pharmacologic means or DC cardioversion =3 episodes of VT treated with antitachycardia pacing (ATP), at least one of which was symptomatic = 5 episodes of VT treated with antitachycardia pacing (ATP) regardless of symptoms =1 appropriate ICD shocks, =3 VT episodes within 24 hours	[ "Prior", "Myocardial", "Infarction", "and", "\n", "Sustained", "monomorphic", "VT", "documented", "on", "12", "-", "lead", "ECG", "or", "rhythm", "strip", "terminated", "by", "pharmacologic", "means", "or", "DC", "cardioversion", "\n", "=3", "episodes", "of", ...	[ { "text": "Myocardial Infarction", "type": "Condition", "char_start": 6, "char_end": 27, "token_start": 1, "token_end": 3 }, { "text": "Sustained", "type": "Qualifier", "char_start": 32, "char_end": 41, "token_start": 5, "token_end": 6 }, { "text": "monomo...	NCT02830360_inc
Patients are not expected to be alive for longer than 3 months. Mini-mental State Examination (MMSE) [18] score = 23. history of dementia, psychiatric illness or any diseases of central nervous system. current use of sedatives or antidepressant. alcoholism and drug dependence. patients previously included in this study (for patients who have second intra-abdominal surgery during the study period). difficult to follow up or patients with poor compliance. uncontrolled hypertension (> 180/100 mmHg)	[ "Patients", "are", "not", "expected", "to", "be", "alive", "for", "longer", "than", "3", "months", ".", "\n", "Mini", "-", "mental", "State", "Examination", "(", "MMSE", ")", "[", "18", "]", "score", "=", "23", ".", "\n", "history", "of", "dementia", ...	[ { "text": "not", "type": "Negation", "char_start": 13, "char_end": 16, "token_start": 2, "token_end": 3 }, { "text": "expected to be alive", "type": "Observation", "char_start": 17, "char_end": 37, "token_start": 3, "token_end": 7 }, { "text": "longer than...	NCT01809041_exc
major elective gastrointestinal, gynecological, prostate or bladder surgery patients who are = 60 years old. the surgery is laparoscopic surgery and is expected to last for = 2 hours under general anesthesia and the patient will stay in hospital for at least 7 days after surgery. lack of serious hearing and vision impairment and be able to read so that neurobehavioral tests can be performed.	[ "major", "elective", "gastrointestinal", ",", "gynecological", ",", "prostate", "or", "bladder", "surgery", "patients", "who", "are", "=", "60", "years", "old", ".", "\n", "the", "surgery", "is", "laparoscopic", "surgery", "and", "is", "expected", "to", "last"...	[ { "text": "elective", "type": "Qualifier", "char_start": 6, "char_end": 14, "token_start": 1, "token_end": 2 }, { "text": "gastrointestinal", "type": "Procedure", "char_start": 15, "char_end": 31, "token_start": 2, "token_end": 3 }, { "text": "gastrointest...	NCT01809041_inc
Patients who do not meet the inclusion criteria and those who have a history of allergic reactions to human albumin, as well as those who have received iodinated contrast during the 7 days prior to surgery and pregnant women, will be excluded from the study.	[ "Patients", "who", "do", "not", "meet", "the", "inclusion", "criteria", "and", "those", "who", "have", "a", "history", "of", "allergic", "reactions", "to", "human", "albumin", ",", "as", "well", "as", "those", "who", "have", "received", "iodinated", "contras...	[ { "text": "not", "type": "Negation", "char_start": 16, "char_end": 19, "token_start": 3, "token_end": 4 }, { "text": "meet the inclusion criteria", "type": "Observation", "char_start": 20, "char_end": 47, "token_start": 4, "token_end": 8 }, { "text": "hist...	NCT03373318_exc
Adult patients (> 18 years) scheduled for cardiopulmonary bypass surgery with Glomerular Filtration Rate (GFR) greater than or equal to 60 and left ventricular ejection fraction greater than or equal to 40%	[ "Adult", "patients", "(", ">", "18", "years", ")", "scheduled", "for", "cardiopulmonary", "bypass", "surgery", "with", "Glomerular", "Filtration", "Rate", "(", "GFR", ")", "greater", "than", "or", "equal", "to", "60", "and", "left", "ventricular", "ejection", ...	[ { "text": "Adult", "type": "Person", "char_start": 0, "char_end": 5, "token_start": 0, "token_end": 1 }, { "text": "> 18 years", "type": "Value", "char_start": 16, "char_end": 26, "token_start": 3, "token_end": 6 }, { "text": "> 18 years", "type": "Sco...	NCT03373318_inc
Amiodarone P-glycoprotein (P-gp) inducers (e.g., rifampin, St. John's wort) Liver biopsy at any time showing mHAI stage 4 or higher fibrosis OR FibroScan within 12 months demonstrating liver stiffness of =9.5 kilo Pascal or AST to platelet ratio index (APRI) =2.0 and Fibrosis-4 (FIB-4) =3.25 NOTE: If APRI and FIB-4 are discordant one of the other forms of fibrosis staging must be used. Known allergy/sensitivity or any hypersensitivity to components of study drugs or their formulation. Hemochromatosis Alpha-1 antitrypsin deficiency Wilson's disease Autoimmune hepatitis Alcoholic liver disease Drug-related liver disease Severe NC confounding conditions (stroke, head injury, or developmental learning disability). Regular use of anti-inflammatory drugs. Current or recent treatment with pegylated interferon (PEG-IFN). Other active inflammatory process (major infection, malignancy, rheumatoid arthritis/autoimmune disorder) within the prior 28 days. Contraindications to magnetic resonance imaging (MRI). Bleeding diathesis, thrombocytopenia, or use of anticoagulants that would contraindicate lumbar puncture. Uncontrolled or active depression or other psychiatric disorder that in the opinion of the site investigator might preclude adherence to study requirements or impact NC functioning and assessments. Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements. Presence of active or acute AIDS-defining opportunistic infections within 12 weeks prior to study entry.	[ "Amiodarone", "\n", "P", "-", "glycoprotein", "(", "P", "-", "gp", ")", "inducers", "(", "e.g.", ",", "rifampin", ",", "St.", "John", "'s", "wort", ")", "\n", "Liver", "biopsy", "at", "any", "time", "showing", "mHAI", "stage", "4", "or", "higher", "f...	[ { "text": "Amiodarone", "type": "Drug", "char_start": 0, "char_end": 10, "token_start": 0, "token_end": 1 }, { "text": "P-glycoprotein (P-gp) inducers", "type": "Drug", "char_start": 11, "char_end": 41, "token_start": 2, "token_end": 11 }, { "text": "rifam...	NCT02650024_exc
Adult (= 18 years old) subjects with chronic genotype 1 HCV and NCI with a GDS greater than or equal to 0.5 (n=60). Presence of chronic HCV infection based on chart review will be defined as positive for anti-HCV antibody or HCV RNA at least 6 months before screening. For the HIV/HCV co-infected group only, subjects must have HIV. HIV status will be obtained through self report. Self report will be confirmed at screening using a HIV-1 point of care test. In the event that point of care test and self-report are discordant, then HIV status will be confirmed by a licensed Western blot or a second antibody test. HIV/HCV co-infected subjects (n=12) must also have a HIV RNA measurement <50 copies/mL at the pre-treatment visit. Platelets >150,000 Aspartate aminotransferase (AST)/Alanine aminotransferase (ALT) <10x upper limit of normal Creatinine clearance >30 milliliters/minute/1.73 centimeter squared	[ "Adult", "(=", "18", "years", "old", ")", "subjects", "with", "chronic", "genotype", "1", "HCV", "and", "NCI", "with", "a", "GDS", "greater", "than", "or", "equal", "to", "0.5", "(", "n", "=", "60", ")", ".", "\n", "Presence", "of", "chronic", "HCV",...	[ { "text": "Adult", "type": "Person", "char_start": 0, "char_end": 5, "token_start": 0, "token_end": 1 }, { "text": "= 18 years old", "type": "Value", "char_start": 7, "char_end": 21, "token_start": 1, "token_end": 5 }, { "text": "old", "type": "Person"...	NCT02650024_inc
Pregnant or nursing (lactating) women HIV positivity Need for dual organ transplant Any contra-indication to liver transplantation per center protocol	[ "Pregnant", "or", "nursing", "(", "lactating", ")", "women", "\n", "HIV", "positivity", "\n", "Need", "for", "dual", "organ", "transplant", "\n", "Any", "contra", "-", "indication", "to", "liver", "transplantation", "per", "center", "protocol", "\n" ]	[ { "text": "Pregnant", "type": "Condition", "char_start": 0, "char_end": 8, "token_start": 0, "token_end": 1 }, { "text": "nursing", "type": "Observation", "char_start": 12, "char_end": 19, "token_start": 2, "token_end": 3 }, { "text": "lactating", "typ...	NCT03208127_exc
Recipient is Age = 18 years Met MGH transplant center criteria, listed for liver transplant HCV naive Able to sign informed consent	[ "Recipient", "is", "Age", "=", "18", "years", "\n", "Met", "MGH", "transplant", "center", "criteria", ",", "listed", "for", "liver", "transplant", "\n", "HCV", "naive", "\n", "Able", "to", "sign", "informed", "consent", "\n" ]	[ { "text": "Age", "type": "Person", "char_start": 13, "char_end": 16, "token_start": 2, "token_end": 3 }, { "text": "= 18 years", "type": "Value", "char_start": 17, "char_end": 27, "token_start": 3, "token_end": 6 }, { "text": "MGH transplant center criteri...	NCT03208127_inc
Subject are pregnant Subject is unable to perform tasks associated with study	[ "Subject", "are", "pregnant", "\n", "Subject", "is", "unable", "to", "perform", "tasks", "associated", "with", "study", " \n \n" ]	[ { "text": "pregnant", "type": "Condition", "char_start": 12, "char_end": 20, "token_start": 2, "token_end": 3 } ]	NCT00926523_exc
Subject are at least 18 years of age Subject has confirmed Pulmonary Hypertension and Interstitial Lung Disease Subject are able to complete study procedures, such as spirometry, and Pulmonary Exercise test.	[ "Subject", "are", "at", "least", "18", "years", "of", "age", "\n", "Subject", "has", "confirmed", "Pulmonary", "Hypertension", "and", "Interstitial", "Lung", "Disease", "\n", "Subject", "are", "able", "to", "complete", "study", "procedures", ",", "such", "as",...	[ { "text": "at least 18 years", "type": "Value", "char_start": 12, "char_end": 29, "token_start": 2, "token_end": 6 }, { "text": "age", "type": "Person", "char_start": 33, "char_end": 36, "token_start": 7, "token_end": 8 }, { "text": "confirmed", "type"...	NCT00926523_inc
Plan for diagnostic-only coronary angiography On colchicine chronically History of intolerance to colchicine Glomerular filtration rate <30mL/minute or on dialysis Active malignancy or infection History of myelodysplasia High-dose statin load <24 hours prior to procedure Use of oral steroids or non-steroidal anti-inflammatory agents other than aspirin within 72 hours or 3 times the agent's half-life (whichever is longer) Use of strong CYP3A4/P-glycoprotein inhibitors (specifically ritonavir, ketoconazole, clarithromycin, cyclosporine, diltiazem and verapamil) Unable to consent Participating in a competing study	[ "Plan", "for", "diagnostic", "-", "only", "coronary", "angiography", "\n", "On", "colchicine", "chronically", "\n", "History", "of", "intolerance", "to", "colchicine", "\n", "Glomerular", "filtration", "rate", "<", "30mL", "/", "minute", "or", "on", "dialysis", ...	[ { "text": "diagnostic-only", "type": "Qualifier", "char_start": 9, "char_end": 24, "token_start": 2, "token_end": 5 }, { "text": "coronary angiography", "type": "Procedure", "char_start": 25, "char_end": 45, "token_start": 5, "token_end": 7 }, { "text": "c...	NCT01709981_exc
Patients must be more than 18 years of age and referred for coronary angiography	[ "Patients", "must", "be", "more", "than", "18", "years", "of", "age", "and", "referred", "for", "coronary", "angiography", "\n" ]	[ { "text": "more than 18 years", "type": "Value", "char_start": 17, "char_end": 35, "token_start": 3, "token_end": 7 }, { "text": "age", "type": "Person", "char_start": 39, "char_end": 42, "token_start": 8, "token_end": 9 }, { "text": "referred for", "t...	NCT01709981_inc
Patients with Non-androgenetic causes of hair loss. Female patients with androgenetic alopecia. Patients who received anti-hair loss treatment within the past six months. Patients with history of bleeding disorders or on anticoagulant therapy. Patients with history of chronic liver disease, cancer or connective tissue disorders. Patients with current scalp infection.	[ "Patients", "with", "Non", "-", "androgenetic", "causes", "of", "hair", "loss", ".", "\n", "Female", "patients", "with", "androgenetic", "alopecia", ".", "\n", "Patients", "who", "received", "anti", "-", "hair", "loss", "treatment", "within", "the", "past", ...	[ { "text": "Non-androgenetic causes of hair loss", "type": "Condition", "char_start": 14, "char_end": 50, "token_start": 2, "token_end": 9 }, { "text": "Female", "type": "Person", "char_start": 52, "char_end": 58, "token_start": 11, "token_end": 12 }, { "te...	NCT03388840_exc
male patients with androgenetic alopecia between 18 years and 60 years	[ "male", "patients", "with", "androgenetic", "alopecia", "between", "18", "years", "and", "60", "years", "\n" ]	[ { "text": "male", "type": "Person", "char_start": 0, "char_end": 4, "token_start": 0, "token_end": 1 }, { "text": "androgenetic alopecia", "type": "Condition", "char_start": 19, "char_end": 40, "token_start": 3, "token_end": 5 }, { "text": "between 18 year...	NCT03388840_inc
Active consumption of alcohol and/or drugs Co-infection with human immunodeficiency virus, hepatitis C virus, or hepatitis D virus History of autoimmune hepatitis Psychiatric disease Evidence of neoplastic diseases of the liver	[ "Active", "consumption", "of", "alcohol", "and/or", "drugs", "\n", "Co", "-", "infection", "with", "human", "immunodeficiency", "virus", ",", "hepatitis", "C", "virus", ",", "or", "hepatitis", "D", "virus", "\n", "History", "of", "autoimmune", "hepatitis", "\n...	[ { "text": "Active", "type": "Qualifier", "char_start": 0, "char_end": 6, "token_start": 0, "token_end": 1 }, { "text": "consumption of", "type": "Condition", "char_start": 7, "char_end": 21, "token_start": 1, "token_end": 3 }, { "text": "consumption of alc...	NCT03208998_exc
HBsAg and HBeAg positive for more than 6 months, HBV DNA detectable with ALT level abnormal lasted for three months and at least time190 IU/L or liver puncture biopsy demonstrated apparent inflammation, never treated before enrolled.	[ "HBsAg", "and", "HBeAg", "positive", "for", "more", "than", "6", "months", ",", "HBV", "DNA", "detectable", "with", "ALT", "level", "abnormal", "lasted", "for", "three", "months", "and", "at", "least", "time190", "IU", "/", "L", "or", "liver", "puncture", ...	[ { "text": "HBsAg", "type": "Condition", "char_start": 0, "char_end": 5, "token_start": 0, "token_end": 1 }, { "text": "HBsAg and HBeAg positive", "type": "Scope", "char_start": 0, "char_end": 24, "token_start": 0, "token_end": 4 }, { "text": "HBeAg positiv...	NCT03208998_inc
An initial plasma sodium concentration of lower than 130 mmol/L An initial plasma sodium concentration of higher than 150 mmol/L An initial plasma potassium concentration of lower than 3.0 mmol/L Need for 10% glucose solution Diabetes Diabetes insipidus Diabetic ketoacidosis Renal disease that needs dialysis Protocol-determined chemotherapy hydration Severe liver disease Inborn errors of metabolism that need protocol-determined fluid therapy	[ "An", "initial", "plasma", "sodium", "concentration", "of", "lower", "than", "130", "mmol", "/", "L", "\n", "An", "initial", "plasma", "sodium", "concentration", "of", "higher", "than", "150", "mmol", "/", "L", "\n", "An", "initial", "plasma", "potassium", ...	[ { "text": "initial", "type": "Multiplier", "char_start": 3, "char_end": 10, "token_start": 1, "token_end": 2 }, { "text": "plasma sodium concentration", "type": "Measurement", "char_start": 11, "char_end": 38, "token_start": 2, "token_end": 5 }, { "text": ...	NCT02926989_exc
Acutely ill hospitalised children Need for intravenous fluid therapy	[ "Acutely", "ill", "hospitalised", "children", "\n", "Need", "for", "intravenous", "fluid", "therapy", "\n" ]	[ { "text": "Acutely ill", "type": "Condition", "char_start": 0, "char_end": 11, "token_start": 0, "token_end": 2 }, { "text": "hospitalised", "type": "Observation", "char_start": 12, "char_end": 24, "token_start": 2, "token_end": 3 }, { "text": "children", ...	NCT02926989_inc
immunization with PPV23 within the last year any confirmed or suspected immunodeficiency condition, including human immunodeficiency virus (HIV) infection, haematological malignancy, or a congenital immunodeficiency history of allergic disease or reactions likely to be exacerbated by any component of the vaccine history of allergic disease likely to be stimulated by the vaccination history or records of immunosuppressive therapy (with the exception of topical corticosteroids) for more than 14 days and within 6 months of vaccination history or evidence of administration of immunoglobulins and/or any blood products during the study period or within the three months preceding the study vaccine use of any other investigational or non-registered drug or vaccine during the study period or within 30 days preceding the study vaccine administration of a vaccine during the period starting one month before the dose of vaccine and ending one month after pregnancy	[ "immunization", "with", "PPV23", "within", "the", "last", "year", "\n", "any", "confirmed", "or", "suspected", "immunodeficiency", "condition", ",", "including", "human", "immunodeficiency", "virus", "(", "HIV", ")", "infection", ",", "haematological", "malignancy",...	[ { "text": "immunization", "type": "Procedure", "char_start": 0, "char_end": 12, "token_start": 0, "token_end": 1 }, { "text": "PPV23", "type": "Drug", "char_start": 18, "char_end": 23, "token_start": 2, "token_end": 3 }, { "text": "within the last year", ...	NCT02370069_exc
Males and females of 18 years of age or older at the time of the vaccination Severe chronic kidney disease (Stage 4 and 5)	[ "Males", "and", "females", "of", "18", "years", "of", "age", "or", "older", "at", "the", "time", "of", "the", "vaccination", "\n", "Severe", "chronic", "kidney", "disease", "(", "Stage", "4", "and", "5", ")", "\n" ]	[ { "text": "Males", "type": "Person", "char_start": 0, "char_end": 5, "token_start": 0, "token_end": 1 }, { "text": "females", "type": "Person", "char_start": 10, "char_end": 17, "token_start": 2, "token_end": 3 }, { "text": "18 years", "type": "Value",...	NCT02370069_inc
Contraindication for propofol administration Contraindication for IAP measurement in supine position with head-of-bed at 0° Other intervention for reduction of IAP planned Previous propofol infusion rate >4 mg/kg/h	[ "Contraindication", "for", "propofol", "administration", "\n", "Contraindication", "for", "IAP", "measurement", "in", "supine", "position", "with", "head", "-", "of", "-", "bed", "at", "0", "°", "\n", "Other", "intervention", "for", "reduction", "of", "IAP", "...	[ { "text": "Contraindication", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "propofol", "type": "Drug", "char_start": 21, "char_end": 29, "token_start": 2, "token_end": 3 }, { "text": "Contraindication"...	NCT02944292_exc
Age 18 years or older Mechanical ventilation IAP between 12 and 20 mmHg in at least two consecutive measurements within 1-12 h Spontaneous breathing activity of at least 6 breaths/minute RASS score between 0 and -4 Physician-led sedation (if sedated; as opposed to nurse-led protocol)	[ "Age", "18", "years", "or", "older", "\n", "Mechanical", "ventilation", "\n", "IAP", "between", "12", "and", "20", "mmHg", "in", "at", "least", "two", "consecutive", "measurements", "within", "1", "-", "12", "h", "\n", "Spontaneous", "breathing", "activity",...	[ { "text": "Age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "18 years or older", "type": "Value", "char_start": 4, "char_end": 21, "token_start": 1, "token_end": 5 }, { "text": "Mechanical ventilation", ...	NCT02944292_inc
Pregnant or breast feeding History of Stomach or esophagus surgery Peptic ulcer or reflux esophagitis Zollinger-Ellison syndrome or primary esophageal motility disorders Malignant tumor Bleeding tendency or coagulopathy Contraindication of ALBIS Long term use of aspirin or P2Y12 receptor antagonist within 1month Patients who tool medicine such as PPI, APA,H2blocker, Muscarine receptor antagonist, anti-gastic agent, antacid, anticaogulant, Bisphosphonate agents, Cytotoxic drug, NSAID, adrenal cortex hormone agents (topical treatment is allowed) Terminal patient	[ "Pregnant", "or", "breast", "feeding", "\n", "History", "of", "Stomach", "or", "esophagus", "surgery", "\n", "Peptic", "ulcer", "or", "reflux", "esophagitis", "\n", "Zollinger", "-", "Ellison", "syndrome", "or", "primary", "esophageal", "motility", "disorders", ...	[ { "text": "tomach", "type": "Procedure", "char_start": 39, "char_end": 45, "token_start": 7, "token_end": 8 }, { "text": "esophagus surgery", "type": "Procedure", "char_start": 49, "char_end": 66, "token_start": 9, "token_end": 11 }, { "text": "urgery", ...	NCT02175186_exc
Age between 20 and 80 years Patients undergoing percutaneous coronary intervention and need to take dual antiplatelet therapy continuously at least 12weeks Modified Lanza Score grade 0-1 measured by upper gastrointestinal endoscopy mild gastrointestinal symptom Creatinen in blood = 3mg/dl BUN = 50mg/dl Birilubin = 3mg/dl AST and ALT = 80U/L	[ "Age", "between", "20", "and", "80", "years", "\n", "Patients", "undergoing", "percutaneous", "coronary", "intervention", "and", "need", "to", "take", "dual", "antiplatelet", "therapy", "continuously", "at", "least", "12weeks", "\n", "Modified", "Lanza", "Score", ...	[ { "text": "Age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "between 20 and 80 years", "type": "Value", "char_start": 4, "char_end": 27, "token_start": 1, "token_end": 6 }, { "text": "percutaneous corona...	NCT02175186_inc
Neurological Congenital malformations and/or those known to impair intestinal motility Additional congenital gastrointestinal abnormalities requiring surgical intervention Congenital Cyanotic heart disease Surgical Closure of abdominal wall defect with prosthetic material (e.g. prosthetic or bio-prosthetic mesh)	[ "Neurological", "Congenital", "malformations", "and/or", "those", "known", "to", "impair", "intestinal", "motility", "\n", "Additional", "congenital", "gastrointestinal", "abnormalities", "requiring", "surgical", "intervention", "\n", "Congenital", "Cyanotic", "heart", "d...	[ { "text": "Neurological Congenital malformations", "type": "Condition", "char_start": 0, "char_end": 37, "token_start": 0, "token_end": 3 }, { "text": "impair intestinal motility", "type": "Condition", "char_start": 60, "char_end": 86, "token_start": 7, "token_end...	NCT03355326_exc
Diagnosis of uncomplicated gastroschisis Gestational age >33 weeks at time of delivery Weight >1900g at time of delivery Transfer of patient to Riley Hospital for Children prior to any abdominal surgery	[ "Diagnosis", "of", "uncomplicated", "gastroschisis", "\n", "Gestational", "age", ">", "33", "weeks", "at", "time", "of", "delivery", "\n", "Weight", ">", "1900", "g", "at", "time", "of", "delivery", "\n", "Transfer", "of", "patient", "to", "Riley", "Hospital...	[ { "text": "uncomplicated", "type": "Qualifier", "char_start": 13, "char_end": 26, "token_start": 2, "token_end": 3 }, { "text": "gastroschisis", "type": "Condition", "char_start": 27, "char_end": 40, "token_start": 3, "token_end": 4 }, { "text": "Gestation...	NCT03355326_inc
age <45 or >80 allergies to medications used in the study history of renal diseases, a coagulation abnormality, a hepatic disease, or drug abuse definite radiographic evidence of osteoarthritis of the glenohumeral joint inflammatory arthritis including rheumatoid arthritis a history of acute trauma systemic conditions associated with chronic pain a history of infection an inability to understand the questionnaires	[ "age", "<", "45", "or", ">", "80", "\n", "allergies", "to", "medications", "used", "in", "the", "study", "\n", "history", "of", "renal", "diseases", ",", "a", "coagulation", "abnormality", ",", "a", "hepatic", "disease", ",", "or", "drug", "abuse", "\n",...	[ { "text": "age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "<45 or >80", "type": "Value", "char_start": 4, "char_end": 14, "token_start": 1, "token_end": 6 }, { "text": "allergies", "type": "Conditi...	NCT02992028_exc
Rotator cuff tear patients undergoing arthroscopic rotator cuff tear	[ "Rotator", "cuff", "tear", "patients", "undergoing", "arthroscopic", "rotator", "cuff", "tear", "\n" ]	[ { "text": "Rotator cuff tear", "type": "Condition", "char_start": 0, "char_end": 17, "token_start": 0, "token_end": 3 }, { "text": "arthroscopic rotator cuff tear", "type": "Procedure", "char_start": 38, "char_end": 68, "token_start": 5, "token_end": 9 } ]	NCT02992028_inc
Pregnancy and lactation Patients with diabetes, Ischemic heart disease (IHD), stroke, malignancy and psychiatric diseases are excluded from study. The patients receiving vitamin supplements or who had clinical evidence for an acute illness, renal dysfunction, thyroid dysfunction, chronic inflammatory diseases, inborn errors of homocysteine, cobalamin or folate metabolism, or any other condition known to interfere with homocysteine metabolism will be excluded Patients who are already involved in any other trial. Patients not willing to fill consent/ assent form are also excluded from study.	[ "Pregnancy", "and", "lactation", "\n", "Patients", "with", "diabetes", ",", "Ischemic", "heart", "disease", "(", "IHD", ")", ",", "stroke", ",", "malignancy", "and", "psychiatric", "diseases", "are", "excluded", "from", "study", ".", "\n", "The", "patients", ...	[ { "text": "Pregnancy", "type": "Condition", "char_start": 0, "char_end": 9, "token_start": 0, "token_end": 1 }, { "text": "lactation", "type": "Condition", "char_start": 14, "char_end": 23, "token_start": 2, "token_end": 3 }, { "text": "diabetes", "typ...	NCT02318446_exc
Diagnosed epileptic patients of either sex with age between 10-19 yrs (<19yrs), coming to the medicine Out Patient /In Patient Departments and undergoing AED therapy for more than 6 months. Epileptics with high homocysteine levels i.e. > 10.9 µmol/L (Normal homocysteine levels are 4.3-9.9 µmol/L for male and 3.3-7.2 µmol/L for female adolescent and a high homocysteine concentration is deaned as at least 11.4 µmol/L for male and at least 10.4 µmol/L for female. Gender mean of high homocysteine concentration is 10.9 µmol/L) [5]	[ "Diagnosed", "epileptic", "patients", "of", "either", "sex", "with", "age", "between", "10", "-", "19", "yrs", "(", "<", "19yrs", ")", ",", "coming", "to", "the", "medicine", "Out", "Patient", "/In", "Patient", "Departments", "and", "undergoing", "AED", "t...	[ { "text": "epileptic", "type": "Condition", "char_start": 10, "char_end": 19, "token_start": 1, "token_end": 2 }, { "text": "age", "type": "Person", "char_start": 48, "char_end": 51, "token_start": 7, "token_end": 8 }, { "text": "between 10-19 yrs", "t...	NCT02318446_inc
Hypersensitivity to the active substance, to FCM or any of its excipients Known serious hypersensitivity to other parenteral iron products Anaemia not attributed to iron deficiency, e.g. other microcytic anaemia Evidence of iron overload or disturbances in the utilisation of iron	[ "Hypersensitivity", "to", "the", "active", "substance", ",", "to", "FCM", "or", "any", "of", "its", "excipients", "\n", "Known", "serious", "hypersensitivity", "to", "other", "parenteral", "iron", "products", "\n", "Anaemia", "not", "attributed", "to", "iron", ...	[ { "text": "Hypersensitivity", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "active substance", "type": "Drug", "char_start": 24, "char_end": 40, "token_start": 3, "token_end": 5 }, { "text": "active su...	NCT03036462_exc
Patients aged at least 18 years Patients with chronic heart failure present for at least 12 months Confirmed presence of iron deficiency Serum haemoglobin of 9.5 to 14.0 g/dL	[ "Patients", "aged", "at", "least", "18", "years", "\n", "Patients", "with", "chronic", "heart", "failure", "present", "for", "at", "least", "12", "months", "\n", "Confirmed", "presence", "of", "iron", "deficiency", "\n", "Serum", "haemoglobin", "of", "9.5", ...	[ { "text": "aged", "type": "Person", "char_start": 9, "char_end": 13, "token_start": 1, "token_end": 2 }, { "text": "at least 18 years", "type": "Value", "char_start": 14, "char_end": 31, "token_start": 2, "token_end": 6 }, { "text": "chronic heart failure"...	NCT03036462_inc
History of any malignancy or other severe diseases Female patients who are pregnant or breastfeeding before or during the three-year follow-up Poor compliance or refusal to participate.	[ "History", "of", "any", "malignancy", "or", "other", "severe", "diseases", "\n", "Female", "patients", "who", "are", "pregnant", "or", "breastfeeding", "before", "or", "during", "the", "three", "-", "year", "follow", "-", "up", "\n", "Poor", "compliance", "o...	[ { "text": "malignancy", "type": "Condition", "char_start": 15, "char_end": 25, "token_start": 3, "token_end": 4 }, { "text": "severe diseases", "type": "Condition", "char_start": 35, "char_end": 50, "token_start": 6, "token_end": 8 }, { "text": "Poor compl...	NCT03513874_exc
Type 1 diabetes according to ADA criterias <5 years. Age= 18 years and less than 70 years. Non-obese: defined as BMI less than 28 kg/m2 Positive for at least one of the anti-islet autoantibodies: GADA, IA2A, ZnT8A Fasting or postprandial plasma C-peptide more than 100 pmol/L Written informed consent from the patient or family representative.	[ "Type", "1", "diabetes", "according", "to", "ADA", "criterias", "<", "5", "years", ".", "\n", "Age", "=", "18", "years", "and", "less", "than", "70", "years", ".", "\n", "Non", "-", "obese", ":", "defined", "as", "BMI", "less", "than", "28", "kg", ...	[ { "text": "Type 1 diabetes", "type": "Condition", "char_start": 0, "char_end": 15, "token_start": 0, "token_end": 3 }, { "text": "ADA criterias", "type": "Qualifier", "char_start": 29, "char_end": 42, "token_start": 5, "token_end": 7 }, { "text": "<5 years...	NCT03513874_inc
Contraindication to Clopidogrel Smoking (current smokers and patients who quit smoking less than six months) Malignancy(diagnosed or under investigation) Haematological disorders (Anaemia, malignancy, bleeding disorders) Women of child-bearing potential Use of corticosteroids/other antithrombotic agents(warfarin) Chronic liver disease (Cirrhosis, malignancy and patients with more than twice the upper limit of liver function tests) Unable to consent. Use of other investigational study drugs within 1 year prior to study entry Previous participation in this study	[ "Contraindication", "to", "Clopidogrel", "\n", "Smoking", "(", "current", "smokers", "and", "patients", "who", "quit", "smoking", "less", "than", "six", "months", ")", "\n", "Malignancy", "(", "diagnosed", "or", "under", "investigation", ")", "\n", "Haematologic...	[ { "text": "Contraindication", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "Clopidogrel", "type": "Drug", "char_start": 20, "char_end": 31, "token_start": 2, "token_end": 3 }, { "text": "Smoking", ...	NCT00728156_exc
Patients with T2DM and CAS as defined below: Clinical definitions T2DM: Diagnosed according to the WHO criteria [53]. CAD:Presence of any one of the following: Angina plus positive exercise tolerance test, enzyme and/or Q wave positive myocardial infarction, angiographic evidence ( >50% stenosis of one vessel), percutaneous or surgical coronary revascularisation. Aged between 18 and 75 Provided written consent for participation in the trial prior to any study-specific procedures or requirements.	[ "Patients", "with", "T2DM", "and", "CAS", "as", "defined", "below", ":", "\n", "Clinical", "definitions", "\n", "T2DM", ":", "Diagnosed", "according", "to", "the", "WHO", "criteria", "[", "53", "]", ".", "\n", "CAD", ":", "Presence", "of", "any", "one", ...	[ { "text": "T2DM", "type": "Condition", "char_start": 14, "char_end": 18, "token_start": 2, "token_end": 3 }, { "text": "CAS", "type": "Condition", "char_start": 23, "char_end": 26, "token_start": 4, "token_end": 5 }, { "text": "T2DM", "type": "Conditio...	NCT00728156_inc
no consent known allergy to administered opioid contraindications to epidural analgesia coagulopathies including platelet count of less than 100,000 spine surgery in past	[ "no", "consent", "\n", "known", "allergy", "to", "administered", "opioid", "\n", "contraindications", "to", "epidural", "analgesia", "\n", "coagulopathies", "including", "platelet", "count", "of", "less", "than", "100", ",", "000", "\n", "spine", "surgery", "in"...	[ { "text": "allergy", "type": "Condition", "char_start": 17, "char_end": 24, "token_start": 4, "token_end": 5 }, { "text": "opioid", "type": "Drug", "char_start": 41, "char_end": 47, "token_start": 7, "token_end": 8 }, { "text": "contraindications", "ty...	NCT03344042_exc
parturient in labour without cervical dilation and regular uterine contractions	[ "parturient", "in", "labour", "without", "cervical", "dilation", "and", "regular", "uterine", "contractions", "\n" ]	[ { "text": "parturient", "type": "Person", "char_start": 0, "char_end": 10, "token_start": 0, "token_end": 1 }, { "text": "labour", "type": "Procedure", "char_start": 14, "char_end": 20, "token_start": 2, "token_end": 3 }, { "text": "without", "type": "...	NCT03344042_inc
Metastatic disease (M1)/stage 4 NSCLC Pleural or pericardial effusion greater than 100 ml in volume as documented by appropriate imaging (positron emission tomography [PET], computed tomography [CT] scan or ultrasound). If an effusion greater than 100 ml is documented by cytology to be free from malignancy and the investigator feels the patient is capable of receiving chemo/radiotherapy for their primary disease/ NSCLC, the investigator should discuss the patient with the study physician at Amgen. Effusions smaller than 100 ml would be acceptable, unless the investigator suspects that the effusion is malignant, in which case the effusions should be evaluated by cytology. Sponsor approval must be obtained before patient is randomized. Plan to remove the tumor surgically before completing the protocol chemo/radiotherapy course Shielding of any part of the esophagus during radiotherapy (including posterior spinal cord shielding) Prior chemotherapy, radiotherapy, or surgery for NSCLC Prior invasive malignancy during the past 3 years other than non-melanomatous skin cancer. Note: Patients with prior surgically-cured malignancies [eg, stage I breast cancer or prostate cancer, in-situ carcinoma of the cervix, etc] are not excluded; however, sponsor approval must be obtained before patient is randomized. Presence or history of dysphagia or conditions predisposing to dysphagia (eg, uncontrolled gastroesophageal reflux disease [GERD], dyspepsia, etc) History of pancreatitis Four weeks or less since completion of treatment using an investigational product/device in another clinical study or presence of any unresolved toxicity from previous treatment Previous treatment on this study or with a fibroblast growth factor Known to be sero-positive for human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) Pregnant or breastfeeding women Known sensitivity to E. coli derived products Compromised ability of the patient to give written informed consent and/or to comply with study procedures Refusal to sign an informed consent form to participate in this study, and sign the hospital information release form, if applicable Unwilling or unable to complete the patient reported outcome (PRO) questionnaires Psychological, social, familial, or geographical reasons that would prevent regular follow-up	[ "Metastatic", "disease", "(", "M1", ")", "/", "stage", "4", "NSCLC", "\n", "Pleural", "or", "pericardial", "effusion", "greater", "than", "100", "ml", "in", "volume", "as", "documented", "by", "appropriate", "imaging", "(", "positron", "emission", "tomography"...	[ { "text": "Metastatic disease", "type": "Condition", "char_start": 0, "char_end": 18, "token_start": 0, "token_end": 2 }, { "text": "(M1)/stage 4", "type": "Condition", "char_start": 19, "char_end": 31, "token_start": 2, "token_end": 8 }, { "text": "NSCLC"...	NCT00094861_exc
Patients with a histologically or cytologically proven diagnosis of NSCLC Unresectable (locally advanced) stage IIIa or IIIb disease Initial radiotherapy field of treatment to encompass greater than or equal to 30% of the esophagus Life expectancy greater than or equal to 6 months Estimated weight loss less than or equal to 10% in the 3 months before study randomization Measurable disease 18 years of age or older Eastern Cooperative Oncology Group (ECOG) performance status of 0 - 2 Hemoglobin (hgb) greater than or equal to 10 g/dL without transfusional support or growth factor use in the 4 weeks before study randomization Absolute neutrophil count (ANC) greater than or equal to 1.5 x 10^9/L without growth factor use in the 2 weeks before study randomization Platelet count greater than or equal to 100 x 10^9/L Serum bilirubin less than or equal to 1.5 x institutional upper limit of normal (ULN) Serum creatinine less than or equal to 2.0 mg/dL (Note: Patients with a serum creatinine greater than or equal to 1.4 and less than or equal to 2.0 mg/dL must demonstrate a 24-hour urinary creatinine clearance greater than or equal to 50 mL/min) Females of childbearing potential: negative serum or urine pregnancy test Patient must give written informed consent before participating in any study-specific procedure, randomization, or receiving investigational product. Patients with reproductive capability must agree to practice adequate contraception methods.	[ "Patients", "with", "a", "histologically", "or", "cytologically", "proven", "diagnosis", "of", "NSCLC", "\n", "Unresectable", "(", "locally", "advanced", ")", "stage", "IIIa", "or", "IIIb", "disease", "\n", "Initial", "radiotherapy", "field", "of", "treatment", ...	[ { "text": "histologically", "type": "Qualifier", "char_start": 16, "char_end": 30, "token_start": 3, "token_end": 4 }, { "text": "histologically or cytologically proven", "type": "Scope", "char_start": 16, "char_end": 54, "token_start": 3, "token_end": 7 }, { ...	NCT00094861_inc

Pregnant or lactating women. Evolutive skin disease on the testing zone (lower back). Patients with a clinically significant disease (chronic, recurrent or active). Systemic corticotherapy or immunosuppressive treatment during the previous month, or local corticoid treatment the week before the patch testing. Local or systemic drug use which interacts with the outcome measures. Exposure to sun or UV radiations, 15 days before the patch testing. Patients deprived of their civic rights, in custody, or subject to a tutorial, judiciary or administrative decision. Patients subject to a protection measure. Patients in a critical medical situation. Patients with a personal situation judged by the investigator as unlikely to be compatible with optimal participation in the study, or which could constitute a risk for the patient. Linguistic barrier or psychological profile preventing the patient from signing the consent form. Patient still in an exclusion period following the participation in another clinical trial. Patients having earned more than 4500€ in indemnities for participation in clinical trials during the previous 12 months, including this study.

[ "Pregnant", "or", "lactating", "women", ".", "\n", "Evolutive", "skin", "disease", "on", "the", "testing", "zone", "(", "lower", "back", ")", ".", "\n", "Patients", "with", "a", "clinically", "significant", "disease", "(", "chronic", ",", "recurrent", "or", ...

[ { "text": "Pregnant", "type": "Condition", "char_start": 0, "char_end": 8, "token_start": 0, "token_end": 1 }, { "text": "lactating", "type": "Condition", "char_start": 12, "char_end": 21, "token_start": 2, "token_end": 3 }, { "text": "women", "type": ...

NCT00445029_exc

For both groups: Patients aged from 18 to 65 years old. Both genders eligible for study. Female participants must use a contraceptive method. Feasibility of patch testing. Participants must be able to understand and sign the Informed Consent, and comply with all aspects of the protocol. Patients must be registered in a social security system or with a health insurance coverage  First group: allergic patients Patients with allergic contact dermatitis to para-phenylenediamine (PPD) based on a history of PPD contact dermatitis and positive PPD patch tests.  Second group : healthy volunteers No history of PPD allergic contact dermatitis, with a negative PPD patch test.

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NCT00445029_inc

age less than 13 years at time of procedure use of pain medication prior to procedure pectus carinatum, Poland's syndrome, or any chest wall anomaly other than pectus excavatum previous repair of pectus excavatum by any technique previous thoracic surgery congenital heart disease bleeding dyscrasia major anesthetic risk factors or history of previous problem with anesthesia pregnancy inability to communicate in English

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NCT02721017_exc

scheduled for Nuss procedure for pectus excavatum correction at least 13 years old at the time of the procedure

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NCT02721017_inc

Any anti-coagulation therapy (apart from rivaroxaban for second objective) Hypersensitivity or allergy to factor Xa inhibitors Acute bacterial endocarditis Bleeding disorder Clinically relevant active bleeding Gastrointestinal ulcer or tumor Hepatic dysfunction with increased bleeding risk Renal failure / patients undergoing dialysis Pregnancy and breast feeding Gastrectomy, biliopancreatic diversion, resection or re-routing of small intestines Feeding tube Recent blood donation Abnormalities of laboratory values: alanine-aminotransferase (ALAT), aspartate-aminotransferase (ASAT), gamma-glutamyl transferase (gammaGT), alkalic phosphatase (AP), bilirubin, amylase, lipase, cystatin C, creatinine, white blood cell count, haemoglobin, platelet count, prothrombin time, aPTT, fibrinogen, thrombin time, factors II,V,VII and X Use of therapeutic or recreational drugs influencing plasmatic coagulation

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NCT02970773_exc

Motor complete tetraplegia for at least 3 months Age from 18 to 74 years Body mass index (BMI) from 18 to 35kg/m2 Informed consent as documented by signature

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NCT02970773_inc

Anaphylactic reaction to a previous dose of TIV(trivalent influenza vaccine) Known IgE( Immunoglobulin E)-mediated hypersensitivity to eggs manifested as hives, swelling of the mouth and throat, difficulty in breathing, hypotension, or shock Guillain-Barré syndrome within eight weeks of a previous influenza vaccine Anaphylactic reaction to neomycin Patients who have had influenza vaccine in two of the three previous years

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NCT02762851_exc

Age = 18 years and NYHA (New York Heart Association) functional class II, III and IV

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NCT02762851_inc

Currently dependent on any substance other than cannabis, alcohol or nicotine; History of any major internal disease (including diabetes, cardiovascular disease, lung disease, liver or kidney disease); An active or any history of neurological disorder, including but not limited to seizure disorder, epilepsy, stroke, neurological disease, cognitive impairment, head trauma with prolonged loss of consciousness (>10 minutes), or migraine headaches; An active or a history of a psychiatric disorder including, but not limited to, depression, schizophrenia, bipolar disorder, anxiety, or other psychiatric disorders; Asthma; Known hypersensitivity or allergy to n-acetylcysteine, or receiving chronic therapy with medication that could interact adversely with n-acetylcysteine within 30 days prior to randomization (i.e., nitroglycerin, ACE inhibitors or antihypertensive drugs, anti-coagulants); Exclusion criteria for MRI: having metal in the body and/or having claustrophobia

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NCT03221231_exc

Current DSM-IV diagnosis of cannabis dependence, >1 week detoxified and abstinent; Able to provide written informed consent and to comply with study procedures. Dutch speaking (Dutch as primary language).

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NCT03221231_inc

Unable or unwilling to provide informed consent. Active ischemia (acute thrombus diagnosed by coronary angiography, or dynamic ST segment changes demonstrated on ECG) or another reversible cause of VT (e.g. drug-induced arrhythmia), had recent acute coronary syndrome within 30 days, coronary revascularization (<90 days bypass surgery, <30 days percutaneous coronary intervention), or have CCS functional class IV angina. Note that biomarker level elevation alone after ventricular arrhythmias does not denote acute coronary syndrome or active ischemia. Are ineligible to take the antiarrhythmic drug to which they would be assigned due to allergy, intolerance or contraindication Are known to have protruding left ventricular thrombus or mechanical aortic and mitral valves Have had a prior catheter ablation procedure for VT Are in renal failure (Creatinine clearance <15 mL/min), have NYHA Functional class IV heart failure, or a systemic illness likely to limit survival to <1 year Have had recent ST elevation myocardial infarction or non-ST elevation MI (< 30 days); note that biomarker elevation alone after ventricular arrhythmias does not denote MI. Are pregnant.

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NCT02830360_exc

Prior Myocardial Infarction and Sustained monomorphic VT documented on 12-lead ECG or rhythm strip terminated by pharmacologic means or DC cardioversion =3 episodes of VT treated with antitachycardia pacing (ATP), at least one of which was symptomatic = 5 episodes of VT treated with antitachycardia pacing (ATP) regardless of symptoms =1 appropriate ICD shocks, =3 VT episodes within 24 hours

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NCT02830360_inc

Patients are not expected to be alive for longer than 3 months. Mini-mental State Examination (MMSE) [18] score = 23. history of dementia, psychiatric illness or any diseases of central nervous system. current use of sedatives or antidepressant. alcoholism and drug dependence. patients previously included in this study (for patients who have second intra-abdominal surgery during the study period). difficult to follow up or patients with poor compliance. uncontrolled hypertension (> 180/100 mmHg)

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NCT01809041_exc

major elective gastrointestinal, gynecological, prostate or bladder surgery patients who are = 60 years old. the surgery is laparoscopic surgery and is expected to last for = 2 hours under general anesthesia and the patient will stay in hospital for at least 7 days after surgery. lack of serious hearing and vision impairment and be able to read so that neurobehavioral tests can be performed.

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NCT01809041_inc

Patients who do not meet the inclusion criteria and those who have a history of allergic reactions to human albumin, as well as those who have received iodinated contrast during the 7 days prior to surgery and pregnant women, will be excluded from the study.

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NCT03373318_exc

Adult patients (> 18 years) scheduled for cardiopulmonary bypass surgery with Glomerular Filtration Rate (GFR) greater than or equal to 60 and left ventricular ejection fraction greater than or equal to 40%

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NCT03373318_inc

Amiodarone P-glycoprotein (P-gp) inducers (e.g., rifampin, St. John's wort) Liver biopsy at any time showing mHAI stage 4 or higher fibrosis OR FibroScan within 12 months demonstrating liver stiffness of =9.5 kilo Pascal or AST to platelet ratio index (APRI) =2.0 and Fibrosis-4 (FIB-4) =3.25 NOTE: If APRI and FIB-4 are discordant one of the other forms of fibrosis staging must be used. Known allergy/sensitivity or any hypersensitivity to components of study drugs or their formulation. Hemochromatosis Alpha-1 antitrypsin deficiency Wilson's disease Autoimmune hepatitis Alcoholic liver disease Drug-related liver disease Severe NC confounding conditions (stroke, head injury, or developmental learning disability). Regular use of anti-inflammatory drugs. Current or recent treatment with pegylated interferon (PEG-IFN). Other active inflammatory process (major infection, malignancy, rheumatoid arthritis/autoimmune disorder) within the prior 28 days. Contraindications to magnetic resonance imaging (MRI). Bleeding diathesis, thrombocytopenia, or use of anticoagulants that would contraindicate lumbar puncture. Uncontrolled or active depression or other psychiatric disorder that in the opinion of the site investigator might preclude adherence to study requirements or impact NC functioning and assessments. Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements. Presence of active or acute AIDS-defining opportunistic infections within 12 weeks prior to study entry.

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NCT02650024_exc

Adult (= 18 years old) subjects with chronic genotype 1 HCV and NCI with a GDS greater than or equal to 0.5 (n=60). Presence of chronic HCV infection based on chart review will be defined as positive for anti-HCV antibody or HCV RNA at least 6 months before screening. For the HIV/HCV co-infected group only, subjects must have HIV. HIV status will be obtained through self report. Self report will be confirmed at screening using a HIV-1 point of care test. In the event that point of care test and self-report are discordant, then HIV status will be confirmed by a licensed Western blot or a second antibody test. HIV/HCV co-infected subjects (n=12) must also have a HIV RNA measurement <50 copies/mL at the pre-treatment visit. Platelets >150,000 Aspartate aminotransferase (AST)/Alanine aminotransferase (ALT) <10x upper limit of normal Creatinine clearance >30 milliliters/minute/1.73 centimeter squared

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NCT02650024_inc

Pregnant or nursing (lactating) women HIV positivity Need for dual organ transplant Any contra-indication to liver transplantation per center protocol

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NCT03208127_exc

Recipient is Age = 18 years Met MGH transplant center criteria, listed for liver transplant HCV naive Able to sign informed consent

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NCT03208127_inc

Subject are pregnant Subject is unable to perform tasks associated with study

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NCT00926523_exc

Subject are at least 18 years of age Subject has confirmed Pulmonary Hypertension and Interstitial Lung Disease Subject are able to complete study procedures, such as spirometry, and Pulmonary Exercise test.

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NCT00926523_inc

Plan for diagnostic-only coronary angiography On colchicine chronically History of intolerance to colchicine Glomerular filtration rate <30mL/minute or on dialysis Active malignancy or infection History of myelodysplasia High-dose statin load <24 hours prior to procedure Use of oral steroids or non-steroidal anti-inflammatory agents other than aspirin within 72 hours or 3 times the agent's half-life (whichever is longer) Use of strong CYP3A4/P-glycoprotein inhibitors (specifically ritonavir, ketoconazole, clarithromycin, cyclosporine, diltiazem and verapamil) Unable to consent Participating in a competing study

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NCT01709981_exc

Patients must be more than 18 years of age and referred for coronary angiography

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NCT01709981_inc

Patients with Non-androgenetic causes of hair loss. Female patients with androgenetic alopecia. Patients who received anti-hair loss treatment within the past six months. Patients with history of bleeding disorders or on anticoagulant therapy. Patients with history of chronic liver disease, cancer or connective tissue disorders. Patients with current scalp infection.

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NCT03388840_exc

male patients with androgenetic alopecia between 18 years and 60 years

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NCT03388840_inc

Active consumption of alcohol and/or drugs Co-infection with human immunodeficiency virus, hepatitis C virus, or hepatitis D virus History of autoimmune hepatitis Psychiatric disease Evidence of neoplastic diseases of the liver

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NCT03208998_exc

HBsAg and HBeAg positive for more than 6 months, HBV DNA detectable with ALT level abnormal lasted for three months and at least time190 IU/L or liver puncture biopsy demonstrated apparent inflammation, never treated before enrolled.

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NCT03208998_inc

An initial plasma sodium concentration of lower than 130 mmol/L An initial plasma sodium concentration of higher than 150 mmol/L An initial plasma potassium concentration of lower than 3.0 mmol/L Need for 10% glucose solution Diabetes Diabetes insipidus Diabetic ketoacidosis Renal disease that needs dialysis Protocol-determined chemotherapy hydration Severe liver disease Inborn errors of metabolism that need protocol-determined fluid therapy

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NCT02926989_exc

Acutely ill hospitalised children Need for intravenous fluid therapy

[ "Acutely", "ill", "hospitalised", "children", "\n", "Need", "for", "intravenous", "fluid", "therapy", "\n" ]

[ { "text": "Acutely ill", "type": "Condition", "char_start": 0, "char_end": 11, "token_start": 0, "token_end": 2 }, { "text": "hospitalised", "type": "Observation", "char_start": 12, "char_end": 24, "token_start": 2, "token_end": 3 }, { "text": "children", ...

NCT02926989_inc

immunization with PPV23 within the last year any confirmed or suspected immunodeficiency condition, including human immunodeficiency virus (HIV) infection, haematological malignancy, or a congenital immunodeficiency history of allergic disease or reactions likely to be exacerbated by any component of the vaccine history of allergic disease likely to be stimulated by the vaccination history or records of immunosuppressive therapy (with the exception of topical corticosteroids) for more than 14 days and within 6 months of vaccination history or evidence of administration of immunoglobulins and/or any blood products during the study period or within the three months preceding the study vaccine use of any other investigational or non-registered drug or vaccine during the study period or within 30 days preceding the study vaccine administration of a vaccine during the period starting one month before the dose of vaccine and ending one month after pregnancy

[ "immunization", "with", "PPV23", "within", "the", "last", "year", "\n", "any", "confirmed", "or", "suspected", "immunodeficiency", "condition", ",", "including", "human", "immunodeficiency", "virus", "(", "HIV", ")", "infection", ",", "haematological", "malignancy",...

[ { "text": "immunization", "type": "Procedure", "char_start": 0, "char_end": 12, "token_start": 0, "token_end": 1 }, { "text": "PPV23", "type": "Drug", "char_start": 18, "char_end": 23, "token_start": 2, "token_end": 3 }, { "text": "within the last year", ...

NCT02370069_exc

Males and females of 18 years of age or older at the time of the vaccination Severe chronic kidney disease (Stage 4 and 5)

[ "Males", "and", "females", "of", "18", "years", "of", "age", "or", "older", "at", "the", "time", "of", "the", "vaccination", "\n", "Severe", "chronic", "kidney", "disease", "(", "Stage", "4", "and", "5", ")", "\n" ]

[ { "text": "Males", "type": "Person", "char_start": 0, "char_end": 5, "token_start": 0, "token_end": 1 }, { "text": "females", "type": "Person", "char_start": 10, "char_end": 17, "token_start": 2, "token_end": 3 }, { "text": "18 years", "type": "Value",...

NCT02370069_inc

Contraindication for propofol administration Contraindication for IAP measurement in supine position with head-of-bed at 0° Other intervention for reduction of IAP planned Previous propofol infusion rate >4 mg/kg/h

[ "Contraindication", "for", "propofol", "administration", "\n", "Contraindication", "for", "IAP", "measurement", "in", "supine", "position", "with", "head", "-", "of", "-", "bed", "at", "0", "°", "\n", "Other", "intervention", "for", "reduction", "of", "IAP", "...

[ { "text": "Contraindication", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "propofol", "type": "Drug", "char_start": 21, "char_end": 29, "token_start": 2, "token_end": 3 }, { "text": "Contraindication"...

NCT02944292_exc

Age 18 years or older Mechanical ventilation IAP between 12 and 20 mmHg in at least two consecutive measurements within 1-12 h Spontaneous breathing activity of at least 6 breaths/minute RASS score between 0 and -4 Physician-led sedation (if sedated; as opposed to nurse-led protocol)

[ "Age", "18", "years", "or", "older", "\n", "Mechanical", "ventilation", "\n", "IAP", "between", "12", "and", "20", "mmHg", "in", "at", "least", "two", "consecutive", "measurements", "within", "1", "-", "12", "h", "\n", "Spontaneous", "breathing", "activity",...

[ { "text": "Age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "18 years or older", "type": "Value", "char_start": 4, "char_end": 21, "token_start": 1, "token_end": 5 }, { "text": "Mechanical ventilation", ...

NCT02944292_inc

Pregnant or breast feeding History of Stomach or esophagus surgery Peptic ulcer or reflux esophagitis Zollinger-Ellison syndrome or primary esophageal motility disorders Malignant tumor Bleeding tendency or coagulopathy Contraindication of ALBIS Long term use of aspirin or P2Y12 receptor antagonist within 1month Patients who tool medicine such as PPI, APA,H2blocker, Muscarine receptor antagonist, anti-gastic agent, antacid, anticaogulant, Bisphosphonate agents, Cytotoxic drug, NSAID, adrenal cortex hormone agents (topical treatment is allowed) Terminal patient

[ "Pregnant", "or", "breast", "feeding", "\n", "History", "of", "Stomach", "or", "esophagus", "surgery", "\n", "Peptic", "ulcer", "or", "reflux", "esophagitis", "\n", "Zollinger", "-", "Ellison", "syndrome", "or", "primary", "esophageal", "motility", "disorders", ...

[ { "text": "tomach", "type": "Procedure", "char_start": 39, "char_end": 45, "token_start": 7, "token_end": 8 }, { "text": "esophagus surgery", "type": "Procedure", "char_start": 49, "char_end": 66, "token_start": 9, "token_end": 11 }, { "text": "urgery", ...

NCT02175186_exc

Age between 20 and 80 years Patients undergoing percutaneous coronary intervention and need to take dual antiplatelet therapy continuously at least 12weeks Modified Lanza Score grade 0-1 measured by upper gastrointestinal endoscopy mild gastrointestinal symptom Creatinen in blood = 3mg/dl BUN = 50mg/dl Birilubin = 3mg/dl AST and ALT = 80U/L

[ "Age", "between", "20", "and", "80", "years", "\n", "Patients", "undergoing", "percutaneous", "coronary", "intervention", "and", "need", "to", "take", "dual", "antiplatelet", "therapy", "continuously", "at", "least", "12weeks", "\n", "Modified", "Lanza", "Score", ...

[ { "text": "Age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "between 20 and 80 years", "type": "Value", "char_start": 4, "char_end": 27, "token_start": 1, "token_end": 6 }, { "text": "percutaneous corona...

NCT02175186_inc

Neurological Congenital malformations and/or those known to impair intestinal motility Additional congenital gastrointestinal abnormalities requiring surgical intervention Congenital Cyanotic heart disease Surgical Closure of abdominal wall defect with prosthetic material (e.g. prosthetic or bio-prosthetic mesh)

[ "Neurological", "Congenital", "malformations", "and/or", "those", "known", "to", "impair", "intestinal", "motility", "\n", "Additional", "congenital", "gastrointestinal", "abnormalities", "requiring", "surgical", "intervention", "\n", "Congenital", "Cyanotic", "heart", "d...

[ { "text": "Neurological Congenital malformations", "type": "Condition", "char_start": 0, "char_end": 37, "token_start": 0, "token_end": 3 }, { "text": "impair intestinal motility", "type": "Condition", "char_start": 60, "char_end": 86, "token_start": 7, "token_end...

NCT03355326_exc

Diagnosis of uncomplicated gastroschisis Gestational age >33 weeks at time of delivery Weight >1900g at time of delivery Transfer of patient to Riley Hospital for Children prior to any abdominal surgery

[ "Diagnosis", "of", "uncomplicated", "gastroschisis", "\n", "Gestational", "age", ">", "33", "weeks", "at", "time", "of", "delivery", "\n", "Weight", ">", "1900", "g", "at", "time", "of", "delivery", "\n", "Transfer", "of", "patient", "to", "Riley", "Hospital...

[ { "text": "uncomplicated", "type": "Qualifier", "char_start": 13, "char_end": 26, "token_start": 2, "token_end": 3 }, { "text": "gastroschisis", "type": "Condition", "char_start": 27, "char_end": 40, "token_start": 3, "token_end": 4 }, { "text": "Gestation...

NCT03355326_inc

age <45 or >80 allergies to medications used in the study history of renal diseases, a coagulation abnormality, a hepatic disease, or drug abuse definite radiographic evidence of osteoarthritis of the glenohumeral joint inflammatory arthritis including rheumatoid arthritis a history of acute trauma systemic conditions associated with chronic pain a history of infection an inability to understand the questionnaires

[ "age", "<", "45", "or", ">", "80", "\n", "allergies", "to", "medications", "used", "in", "the", "study", "\n", "history", "of", "renal", "diseases", ",", "a", "coagulation", "abnormality", ",", "a", "hepatic", "disease", ",", "or", "drug", "abuse", "\n",...

[ { "text": "age", "type": "Person", "char_start": 0, "char_end": 3, "token_start": 0, "token_end": 1 }, { "text": "<45 or >80", "type": "Value", "char_start": 4, "char_end": 14, "token_start": 1, "token_end": 6 }, { "text": "allergies", "type": "Conditi...

NCT02992028_exc

Rotator cuff tear patients undergoing arthroscopic rotator cuff tear

[ "Rotator", "cuff", "tear", "patients", "undergoing", "arthroscopic", "rotator", "cuff", "tear", "\n" ]

[ { "text": "Rotator cuff tear", "type": "Condition", "char_start": 0, "char_end": 17, "token_start": 0, "token_end": 3 }, { "text": "arthroscopic rotator cuff tear", "type": "Procedure", "char_start": 38, "char_end": 68, "token_start": 5, "token_end": 9 } ]

NCT02992028_inc

Pregnancy and lactation Patients with diabetes, Ischemic heart disease (IHD), stroke, malignancy and psychiatric diseases are excluded from study. The patients receiving vitamin supplements or who had clinical evidence for an acute illness, renal dysfunction, thyroid dysfunction, chronic inflammatory diseases, inborn errors of homocysteine, cobalamin or folate metabolism, or any other condition known to interfere with homocysteine metabolism will be excluded Patients who are already involved in any other trial. Patients not willing to fill consent/ assent form are also excluded from study.

[ "Pregnancy", "and", "lactation", "\n", "Patients", "with", "diabetes", ",", "Ischemic", "heart", "disease", "(", "IHD", ")", ",", "stroke", ",", "malignancy", "and", "psychiatric", "diseases", "are", "excluded", "from", "study", ".", "\n", "The", "patients", ...

[ { "text": "Pregnancy", "type": "Condition", "char_start": 0, "char_end": 9, "token_start": 0, "token_end": 1 }, { "text": "lactation", "type": "Condition", "char_start": 14, "char_end": 23, "token_start": 2, "token_end": 3 }, { "text": "diabetes", "typ...

NCT02318446_exc

Diagnosed epileptic patients of either sex with age between 10-19 yrs (<19yrs), coming to the medicine Out Patient /In Patient Departments and undergoing AED therapy for more than 6 months. Epileptics with high homocysteine levels i.e. > 10.9 µmol/L (Normal homocysteine levels are 4.3-9.9 µmol/L for male and 3.3-7.2 µmol/L for female adolescent and a high homocysteine concentration is deaned as at least 11.4 µmol/L for male and at least 10.4 µmol/L for female. Gender mean of high homocysteine concentration is 10.9 µmol/L) [5]

[ "Diagnosed", "epileptic", "patients", "of", "either", "sex", "with", "age", "between", "10", "-", "19", "yrs", "(", "<", "19yrs", ")", ",", "coming", "to", "the", "medicine", "Out", "Patient", "/In", "Patient", "Departments", "and", "undergoing", "AED", "t...

[ { "text": "epileptic", "type": "Condition", "char_start": 10, "char_end": 19, "token_start": 1, "token_end": 2 }, { "text": "age", "type": "Person", "char_start": 48, "char_end": 51, "token_start": 7, "token_end": 8 }, { "text": "between 10-19 yrs", "t...

NCT02318446_inc

Hypersensitivity to the active substance, to FCM or any of its excipients Known serious hypersensitivity to other parenteral iron products Anaemia not attributed to iron deficiency, e.g. other microcytic anaemia Evidence of iron overload or disturbances in the utilisation of iron

[ "Hypersensitivity", "to", "the", "active", "substance", ",", "to", "FCM", "or", "any", "of", "its", "excipients", "\n", "Known", "serious", "hypersensitivity", "to", "other", "parenteral", "iron", "products", "\n", "Anaemia", "not", "attributed", "to", "iron", ...

[ { "text": "Hypersensitivity", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "active substance", "type": "Drug", "char_start": 24, "char_end": 40, "token_start": 3, "token_end": 5 }, { "text": "active su...

NCT03036462_exc

Patients aged at least 18 years Patients with chronic heart failure present for at least 12 months Confirmed presence of iron deficiency Serum haemoglobin of 9.5 to 14.0 g/dL

[ "Patients", "aged", "at", "least", "18", "years", "\n", "Patients", "with", "chronic", "heart", "failure", "present", "for", "at", "least", "12", "months", "\n", "Confirmed", "presence", "of", "iron", "deficiency", "\n", "Serum", "haemoglobin", "of", "9.5", ...

[ { "text": "aged", "type": "Person", "char_start": 9, "char_end": 13, "token_start": 1, "token_end": 2 }, { "text": "at least 18 years", "type": "Value", "char_start": 14, "char_end": 31, "token_start": 2, "token_end": 6 }, { "text": "chronic heart failure"...

NCT03036462_inc

History of any malignancy or other severe diseases Female patients who are pregnant or breastfeeding before or during the three-year follow-up Poor compliance or refusal to participate.

[ "History", "of", "any", "malignancy", "or", "other", "severe", "diseases", "\n", "Female", "patients", "who", "are", "pregnant", "or", "breastfeeding", "before", "or", "during", "the", "three", "-", "year", "follow", "-", "up", "\n", "Poor", "compliance", "o...

[ { "text": "malignancy", "type": "Condition", "char_start": 15, "char_end": 25, "token_start": 3, "token_end": 4 }, { "text": "severe diseases", "type": "Condition", "char_start": 35, "char_end": 50, "token_start": 6, "token_end": 8 }, { "text": "Poor compl...

NCT03513874_exc

Type 1 diabetes according to ADA criterias <5 years. Age= 18 years and less than 70 years. Non-obese: defined as BMI less than 28 kg/m2 Positive for at least one of the anti-islet autoantibodies: GADA, IA2A, ZnT8A Fasting or postprandial plasma C-peptide more than 100 pmol/L Written informed consent from the patient or family representative.

[ "Type", "1", "diabetes", "according", "to", "ADA", "criterias", "<", "5", "years", ".", "\n", "Age", "=", "18", "years", "and", "less", "than", "70", "years", ".", "\n", "Non", "-", "obese", ":", "defined", "as", "BMI", "less", "than", "28", "kg", ...

[ { "text": "Type 1 diabetes", "type": "Condition", "char_start": 0, "char_end": 15, "token_start": 0, "token_end": 3 }, { "text": "ADA criterias", "type": "Qualifier", "char_start": 29, "char_end": 42, "token_start": 5, "token_end": 7 }, { "text": "<5 years...

NCT03513874_inc

Contraindication to Clopidogrel Smoking (current smokers and patients who quit smoking less than six months) Malignancy(diagnosed or under investigation) Haematological disorders (Anaemia, malignancy, bleeding disorders) Women of child-bearing potential Use of corticosteroids/other antithrombotic agents(warfarin) Chronic liver disease (Cirrhosis, malignancy and patients with more than twice the upper limit of liver function tests) Unable to consent. Use of other investigational study drugs within 1 year prior to study entry Previous participation in this study

[ "Contraindication", "to", "Clopidogrel", "\n", "Smoking", "(", "current", "smokers", "and", "patients", "who", "quit", "smoking", "less", "than", "six", "months", ")", "\n", "Malignancy", "(", "diagnosed", "or", "under", "investigation", ")", "\n", "Haematologic...

[ { "text": "Contraindication", "type": "Condition", "char_start": 0, "char_end": 16, "token_start": 0, "token_end": 1 }, { "text": "Clopidogrel", "type": "Drug", "char_start": 20, "char_end": 31, "token_start": 2, "token_end": 3 }, { "text": "Smoking", ...

NCT00728156_exc

Patients with T2DM and CAS as defined below: Clinical definitions T2DM: Diagnosed according to the WHO criteria [53]. CAD:Presence of any one of the following: Angina plus positive exercise tolerance test, enzyme and/or Q wave positive myocardial infarction, angiographic evidence ( >50% stenosis of one vessel), percutaneous or surgical coronary revascularisation. Aged between 18 and 75 Provided written consent for participation in the trial prior to any study-specific procedures or requirements.

[ "Patients", "with", "T2DM", "and", "CAS", "as", "defined", "below", ":", "\n", "Clinical", "definitions", "\n", "T2DM", ":", "Diagnosed", "according", "to", "the", "WHO", "criteria", "[", "53", "]", ".", "\n", "CAD", ":", "Presence", "of", "any", "one", ...

[ { "text": "T2DM", "type": "Condition", "char_start": 14, "char_end": 18, "token_start": 2, "token_end": 3 }, { "text": "CAS", "type": "Condition", "char_start": 23, "char_end": 26, "token_start": 4, "token_end": 5 }, { "text": "T2DM", "type": "Conditio...

NCT00728156_inc

no consent known allergy to administered opioid contraindications to epidural analgesia coagulopathies including platelet count of less than 100,000 spine surgery in past

[ "no", "consent", "\n", "known", "allergy", "to", "administered", "opioid", "\n", "contraindications", "to", "epidural", "analgesia", "\n", "coagulopathies", "including", "platelet", "count", "of", "less", "than", "100", ",", "000", "\n", "spine", "surgery", "in"...

[ { "text": "allergy", "type": "Condition", "char_start": 17, "char_end": 24, "token_start": 4, "token_end": 5 }, { "text": "opioid", "type": "Drug", "char_start": 41, "char_end": 47, "token_start": 7, "token_end": 8 }, { "text": "contraindications", "ty...

NCT03344042_exc

parturient in labour without cervical dilation and regular uterine contractions

[ "parturient", "in", "labour", "without", "cervical", "dilation", "and", "regular", "uterine", "contractions", "\n" ]

[ { "text": "parturient", "type": "Person", "char_start": 0, "char_end": 10, "token_start": 0, "token_end": 1 }, { "text": "labour", "type": "Procedure", "char_start": 14, "char_end": 20, "token_start": 2, "token_end": 3 }, { "text": "without", "type": "...

NCT03344042_inc

Metastatic disease (M1)/stage 4 NSCLC Pleural or pericardial effusion greater than 100 ml in volume as documented by appropriate imaging (positron emission tomography [PET], computed tomography [CT] scan or ultrasound). If an effusion greater than 100 ml is documented by cytology to be free from malignancy and the investigator feels the patient is capable of receiving chemo/radiotherapy for their primary disease/ NSCLC, the investigator should discuss the patient with the study physician at Amgen. Effusions smaller than 100 ml would be acceptable, unless the investigator suspects that the effusion is malignant, in which case the effusions should be evaluated by cytology. Sponsor approval must be obtained before patient is randomized. Plan to remove the tumor surgically before completing the protocol chemo/radiotherapy course Shielding of any part of the esophagus during radiotherapy (including posterior spinal cord shielding) Prior chemotherapy, radiotherapy, or surgery for NSCLC Prior invasive malignancy during the past 3 years other than non-melanomatous skin cancer. Note: Patients with prior surgically-cured malignancies [eg, stage I breast cancer or prostate cancer, in-situ carcinoma of the cervix, etc] are not excluded; however, sponsor approval must be obtained before patient is randomized. Presence or history of dysphagia or conditions predisposing to dysphagia (eg, uncontrolled gastroesophageal reflux disease [GERD], dyspepsia, etc) History of pancreatitis Four weeks or less since completion of treatment using an investigational product/device in another clinical study or presence of any unresolved toxicity from previous treatment Previous treatment on this study or with a fibroblast growth factor Known to be sero-positive for human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) Pregnant or breastfeeding women Known sensitivity to E. coli derived products Compromised ability of the patient to give written informed consent and/or to comply with study procedures Refusal to sign an informed consent form to participate in this study, and sign the hospital information release form, if applicable Unwilling or unable to complete the patient reported outcome (PRO) questionnaires Psychological, social, familial, or geographical reasons that would prevent regular follow-up

[ "Metastatic", "disease", "(", "M1", ")", "/", "stage", "4", "NSCLC", "\n", "Pleural", "or", "pericardial", "effusion", "greater", "than", "100", "ml", "in", "volume", "as", "documented", "by", "appropriate", "imaging", "(", "positron", "emission", "tomography"...

[ { "text": "Metastatic disease", "type": "Condition", "char_start": 0, "char_end": 18, "token_start": 0, "token_end": 2 }, { "text": "(M1)/stage 4", "type": "Condition", "char_start": 19, "char_end": 31, "token_start": 2, "token_end": 8 }, { "text": "NSCLC"...

NCT00094861_exc

Patients with a histologically or cytologically proven diagnosis of NSCLC Unresectable (locally advanced) stage IIIa or IIIb disease Initial radiotherapy field of treatment to encompass greater than or equal to 30% of the esophagus Life expectancy greater than or equal to 6 months Estimated weight loss less than or equal to 10% in the 3 months before study randomization Measurable disease 18 years of age or older Eastern Cooperative Oncology Group (ECOG) performance status of 0 - 2 Hemoglobin (hgb) greater than or equal to 10 g/dL without transfusional support or growth factor use in the 4 weeks before study randomization Absolute neutrophil count (ANC) greater than or equal to 1.5 x 10^9/L without growth factor use in the 2 weeks before study randomization Platelet count greater than or equal to 100 x 10^9/L Serum bilirubin less than or equal to 1.5 x institutional upper limit of normal (ULN) Serum creatinine less than or equal to 2.0 mg/dL (Note: Patients with a serum creatinine greater than or equal to 1.4 and less than or equal to 2.0 mg/dL must demonstrate a 24-hour urinary creatinine clearance greater than or equal to 50 mL/min) Females of childbearing potential: negative serum or urine pregnancy test Patient must give written informed consent before participating in any study-specific procedure, randomization, or receiving investigational product. Patients with reproductive capability must agree to practice adequate contraception methods.

[ "Patients", "with", "a", "histologically", "or", "cytologically", "proven", "diagnosis", "of", "NSCLC", "\n", "Unresectable", "(", "locally", "advanced", ")", "stage", "IIIa", "or", "IIIb", "disease", "\n", "Initial", "radiotherapy", "field", "of", "treatment", ...

[ { "text": "histologically", "type": "Qualifier", "char_start": 16, "char_end": 30, "token_start": 3, "token_end": 4 }, { "text": "histologically or cytologically proven", "type": "Scope", "char_start": 16, "char_end": 54, "token_start": 3, "token_end": 7 }, { ...

NCT00094861_inc

Datasets:

anurag-raapid
/

chia

Collection including anurag-raapid/chia

Clinical NER Dataset