Discovery
Collection
TBD • 6 items • Updated
Datasets:
pair_id stringlengths 15 18 | split stringclasses 1
value | reference_assembly stringclasses 1
value | chromosome stringclasses 1
value | reference_allele stringclasses 4
values | alternate_allele stringclasses 15
values | data_project stringclasses 2
values | oligo stringclasses 26
values | variant_class stringclasses 72
values | reference_id stringlengths 20 23 | alternate_id stringlengths 20 23 | reference_sequence stringlengths 197 200 | alternate_sequence stringlengths 200 200 | position int64 19.8M 53.2M | reference_sequence_length int64 197 200 | alternate_sequence_length int64 200 200 | sequence_length_change int64 0 3 | K562_reference_log2FC float64 -1.19 6.7 | K562_alternate_log2FC float64 -1.33 7.26 | K562_delta_log2FC float64 -2.2 2.15 | K562_reference_lfcSE float64 0.07 0.96 | K562_alternate_lfcSE float64 0.07 0.94 | K562_delta_lfcSE_independent float64 0.1 1.34 | HepG2_reference_log2FC float64 -1.37 6.47 | HepG2_alternate_log2FC float64 -1.34 6.61 | HepG2_delta_log2FC float64 -1.64 2.2 | HepG2_reference_lfcSE float64 0.05 0.9 | HepG2_alternate_lfcSE float64 0.05 0.77 | HepG2_delta_lfcSE_independent float64 0.07 1.17 | SKNSH_reference_log2FC float64 -1.34 7.71 | SKNSH_alternate_log2FC float64 -1.84 7.68 | SKNSH_delta_log2FC float64 -2.22 3 | SKNSH_reference_lfcSE float64 0.06 0.97 | SKNSH_alternate_lfcSE float64 0.06 0.94 | SKNSH_delta_lfcSE_independent float64 0.08 1.35 | task stringclasses 1
value | source stringclasses 1
value | system_prompt stringclasses 1
value | prompt stringlengths 783 794 | completion stringclasses 9
values | messages listlengths 2 2 | prompt_messages listlengths 1 1 | metadata_json stringlengths 549 557 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
13:19795757:C:T | test | grch37 | 13 | C | T | GTEX | 41 | GTEx | 13:19795757:C:T:R:wC | 13:19795757:C:T:A:wC | TGACTTACCAAAGTGGGAGGCTGCCTCGGCCTCTGAAAGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCGGCCTGGCCAACATGGCAAAACACTGTCTCTACTAAAACTACAAAAATAAGCCGGGCATGGTGGCACACGCCTGTAGTCCCAGCTACTCAAGGAGGCTGA | TGACTTACCAAAGTGGGAGGCTGCCTCGGCCTCTGAAAGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTTGAGACTGGCCTGGCCAACATGGCAAAACACTGTCTCTACTAAAACTACAAAAATAAGCCGGGCATGGTGGCACACGCCTGTAGTCCCAGCTACTCAAGGAGGCTGA | 19,795,757 | 200 | 200 | 0 | -0.033188 | 0.094107 | 0.127295 | 0.178286 | 0.340036 | 0.383941 | -0.204311 | 0.110759 | 0.315071 | 0.07227 | 0.124385 | 0.143856 | 0.171631 | -0.122841 | -0.294472 | 0.128102 | 0.172603 | 0.214946 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:19795757:C:T","position":19795... |
13:19902411:G:T | test | grch37 | 13 | G | T | UKBB | 30 | AST | 13:19902411:G:T:R:wC | 13:19902411:G:T:A:wC | TAGAAAATAATTTAAATTCGACTGTTAAAATTATTACTCTATGTCTAGCTCCTCCTAAATCACTGGATTATAATTAAGAAGTAAAAAATAATTTACCTCGCCCTAAAGTAGGAGTGAAACATGAACCAGCAAACTGTCATTGTTTGTTTGCACTCAACTTAATTCATGATGTGTTTCAATAGGATGGCTGTAGTCAGTAA | TAGAAAATAATTTAAATTCGACTGTTAAAATTATTACTCTATGTCTAGCTCCTCCTAAATCACTGGATTATAATTAAGAAGTAAAAAATAATTTACCTCTCCCTAAAGTAGGAGTGAAACATGAACCAGCAAACTGTCATTGTTTGTTTGCACTCAACTTAATTCATGATGTGTTTCAATAGGATGGCTGTAGTCAGTAA | 19,902,411 | 200 | 200 | 0 | 0.956548 | 1.122368 | 0.16582 | 0.107763 | 0.106337 | 0.151395 | 0.918356 | 1.049186 | 0.13083 | 0.092452 | 0.092534 | 0.130805 | 0.646049 | 0.668248 | 0.0222 | 0.076107 | 0.078338 | 0.10922 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:19902411:G:T","position":19902... |
13:19941835:T:C | test | grch37 | 13 | T | C | GTEX | 41 | GTEx | 13:19941835:T:C:R:wC | 13:19941835:T:C:A:wC | GCCATCTCGGCTCACTGCAAGCTCCGCCTCCAGGGTTCACGCCATTCTCCTGCCTTAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCACCGCACCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGATTTCACTGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTCATGAACCGCCCGCCTCAGCCTCCCAA | GCCATCTCGGCTCACTGCAAGCTCCGCCTCCAGGGTTCACGCCATTCTCCTGCCTTAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCACCGCACCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGATTTCACTGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTCATGAACCGCCCGCCTCAGCCTCCCAA | 19,941,835 | 200 | 200 | 0 | 1.183514 | 0.750211 | -0.433304 | 0.251518 | 0.241566 | 0.348734 | 0.734825 | 0.854372 | 0.119547 | 0.116374 | 0.085527 | 0.144422 | 0.233831 | 0.408548 | 0.174718 | 0.215558 | 0.162508 | 0.269952 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:19941835:T:C","position":19941... |
13:19942440:C:T | test | grch37 | 13 | C | T | GTEX | 42 | GTEx | 13:19942440:C:T:R:wC | 13:19942440:C:T:A:wC | CCCAGGGTTTGAGTGTTGCCCTGCCACCCTGCAGTCTTGAAACTGCATACCTTTTGCGCTCCACCTTCTCTCCGATGGGAATGAGAGAAATTGAAGGCACTGAGTAAATTGCCATGTGTGGTGCGTGTGTTAGCCATAGTAATGCGAGCATACAAGAGTATATTCACTTCTCAGAGTATCATGAGCCCAAACAATTACAG | CCCAGGGTTTGAGTGTTGCCCTGCCACCCTGCAGTCTTGAAACTGCATACCTTTTGCGCTCCACCTTCTCTCCGATGGGAATGAGAGAAATTGAAGGCATTGAGTAAATTGCCATGTGTGGTGCGTGTGTTAGCCATAGTAATGCGAGCATACAAGAGTATATTCACTTCTCAGAGTATCATGAGCCCAAACAATTACAG | 19,942,440 | 200 | 200 | 0 | -0.606601 | -0.427652 | 0.178949 | 0.22723 | 0.244961 | 0.334125 | -0.380154 | -0.499431 | -0.119277 | 0.190749 | 0.190407 | 0.269519 | -0.668049 | -0.631663 | 0.036386 | 0.373113 | 0.462681 | 0.59438 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:19942440:C:T","position":19942... |
13:20135609:G:C | test | grch37 | 13 | G | C | GTEX | 42 | GTEx | 13:20135609:G:C:R:wC | 13:20135609:G:C:A:wC | TCCCGCTGTCGCAGACGCCGCCACCTCCCGGGGCGCCGCGCCCCGCCCCCCAACCTAAGCACACCTTTGGGAAGTTGCCTAAAGTTGCTACGCCTCCCCGCAAGCCCCGACGCCCGCGGGAGACCGCTACCAGGTTATCAGGAAGTAAGTGGGGAGAGCCAAGGAAGAGGAAGTTCTTCCCGGCCGTTGCGATGACCTTT | TCCCGCTGTCGCAGACGCCGCCACCTCCCGGGGCGCCGCGCCCCGCCCCCCAACCTAAGCACACCTTTGGGAAGTTGCCTAAAGTTGCTACGCCTCCCCCCAAGCCCCGACGCCCGCGGGAGACCGCTACCAGGTTATCAGGAAGTAAGTGGGGAGAGCCAAGGAAGAGGAAGTTCTTCCCGGCCGTTGCGATGACCTTT | 20,135,609 | 200 | 200 | 0 | 4.244955 | 4.190709 | -0.054246 | 0.077093 | 0.072164 | 0.105598 | 2.976032 | 2.89513 | -0.080903 | 0.08339 | 0.087537 | 0.1209 | 4.045984 | 3.815953 | -0.230031 | 0.097223 | 0.112548 | 0.148726 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:20135609:G:C","position":20135... |
13:20464188:G:A | test | grch37 | 13 | G | A | GTEX | 42 | GTEx | 13:20464188:G:A:R:wC | 13:20464188:G:A:A:wC | AGCGTATTAGTATTTTCAATCTTGGTAGGATTGTTTTGACCTAACTAGATTGGAAATACACACAGGACTACACCTCAAACTGCCAAAACTCATAAAAGGGCATGTTAGATTAGAATATCTATTCCTTTGATTTAGATATCCCTGTTTTTGAGACTCCATCTTATAGGAATAGAAGCATTTGTATCGAGAAACGTATATCC | AGCGTATTAGTATTTTCAATCTTGGTAGGATTGTTTTGACCTAACTAGATTGGAAATACACACAGGACTACACCTCAAACTGCCAAAACTCATAAAAGGACATGTTAGATTAGAATATCTATTCCTTTGATTTAGATATCCCTGTTTTTGAGACTCCATCTTATAGGAATAGAAGCATTTGTATCGAGAAACGTATATCC | 20,464,188 | 200 | 200 | 0 | -0.185411 | -0.294236 | -0.108824 | 0.226947 | 0.278135 | 0.358977 | -0.065523 | -0.164448 | -0.098925 | 0.146374 | 0.170431 | 0.22466 | 0.323031 | 0.329164 | 0.006133 | 0.282249 | 0.265752 | 0.387671 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:20464188:G:A","position":20464... |
13:20734672:C:T | test | grch37 | 13 | C | T | GTEX | 42 | GTEx | 13:20734672:C:T:R:wC | 13:20734672:C:T:A:wC | GCGCGCCGTTAGCTGGCGCGGTGACATCTGCTTAGAGTTTTCAAGCATTTCAGCATCGCTAGGAGCCCTACAGCCTGACGGTCCGGGACAGCCCGGCTTCCTCCACCCGAGGGGGAAAACAACCCCAGGAAAACAACTTAAACTCGGCCTTGGACTGTCCATCAAGGGAAGCCAAACGAGGCGCTGCTCTCCAGACCTCC | GCGCGCCGTTAGCTGGCGCGGTGACATCTGCTTAGAGTTTTCAAGCATTTCAGCATCGCTAGGAGCCCTACAGCCTGACGGTCCGGGACAGCCCGGCTTTCTCCACCCGAGGGGGAAAACAACCCCAGGAAAACAACTTAAACTCGGCCTTGGACTGTCCATCAAGGGAAGCCAAACGAGGCGCTGCTCTCCAGACCTCC | 20,734,672 | 200 | 200 | 0 | 1.05502 | 0.749067 | -0.305953 | 0.269375 | 0.190461 | 0.329906 | 1.168874 | 0.781124 | -0.38775 | 0.243883 | 0.145723 | 0.284103 | 0.890796 | 0.790268 | -0.100528 | 0.415212 | 0.282891 | 0.502423 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:20734672:C:T","position":20734... |
13:20761888:C:T | test | grch37 | 13 | C | T | GTEX | 42 | GTEx | 13:20761888:C:T:R:wC | 13:20761888:C:T:A:wC | CCATGTCAAGCATAATGGCAATATTCAGGTTCAATCTTCCTATAGATCTGCTCAATATTTATCTAAACCTTAGCTTCTATTCTTTTCACATGTTATTAGCTATATTTTCACTTAAAAAATTGGAGGCTGAAGGGGTAAGCAAACAAACTTTTGAAGTAGACAAAGCTCATCTTTAATCAACAGACTTTAGAGTCCAGTCT | CCATGTCAAGCATAATGGCAATATTCAGGTTCAATCTTCCTATAGATCTGCTCAATATTTATCTAAACCTTAGCTTCTATTCTTTTCACATGTTATTAGTTATATTTTCACTTAAAAAATTGGAGGCTGAAGGGGTAAGCAAACAAACTTTTGAAGTAGACAAAGCTCATCTTTAATCAACAGACTTTAGAGTCCAGTCT | 20,761,888 | 200 | 200 | 0 | 0.216347 | 0.204912 | -0.011435 | 0.202189 | 0.25356 | 0.324304 | 0.513748 | 0.153421 | -0.360326 | 0.150691 | 0.155688 | 0.216672 | -0.061647 | -0.563549 | -0.501902 | 0.274705 | 0.380479 | 0.469284 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:20761888:C:T","position":20761... |
13:20765831:T:C | test | grch37 | 13 | T | C | GTEX | 42 | GTEx | 13:20765831:T:C:R:wC | 13:20765831:T:C:A:wC | GGACGAAGTTGTTTTCAATATTCAAGTCAGAGGAGGAGCTGCCCTCCTGGCCTCCCGACCCTGGGCGGTTACATGCAGCTTCCTACCGGGCCCACGCCATCCTGCACCGCCTGGAGGGCTGCCAGAGGCCAGCGGAGGAGTTGGTTCAGTTCCTTAGGGAAGACACTAGGTGAATCACCAGGATCCAGAAAAGGCAAAAG | GGACGAAGTTGTTTTCAATATTCAAGTCAGAGGAGGAGCTGCCCTCCTGGCCTCCCGACCCTGGGCGGTTACATGCAGCTTCCTACCGGGCCCACGCCACCCTGCACCGCCTGGAGGGCTGCCAGAGGCCAGCGGAGGAGTTGGTTCAGTTCCTTAGGGAAGACACTAGGTGAATCACCAGGATCCAGAAAAGGCAAAAG | 20,765,831 | 200 | 200 | 0 | 1.918478 | 1.652154 | -0.266324 | 0.103152 | 0.131801 | 0.167368 | 0.998877 | 0.977759 | -0.021119 | 0.105943 | 0.131614 | 0.168956 | 2.083703 | 1.561357 | -0.522346 | 0.181601 | 0.168361 | 0.247638 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:20765831:T:C","position":20765... |
13:20807243:C:G | test | grch37 | 13 | C | G | GTEX | 42 | GTEx | 13:20807243:C:G:R:wC | 13:20807243:C:G:A:wC | CATTGCCTCCCCGCTTTTCAGTCAAGACTAGAAAGCTCAGGGCCAGTACAGGGAGTGGTGCAAGGGCTGGTGGGGTGGAAACGTTGGAAGCTATTTAGGCACCTGGCTTTACAGGTTCAAACCTGTCACGCATCGGACAAAAGATGTGTGACTTGCTTATTCTACAAAACTGTTCGGTAATTAAACGTCCCCACCTAAAC | CATTGCCTCCCCGCTTTTCAGTCAAGACTAGAAAGCTCAGGGCCAGTACAGGGAGTGGTGCAAGGGCTGGTGGGGTGGAAACGTTGGAAGCTATTTAGGGACCTGGCTTTACAGGTTCAAACCTGTCACGCATCGGACAAAAGATGTGTGACTTGCTTATTCTACAAAACTGTTCGGTAATTAAACGTCCCCACCTAAAC | 20,807,243 | 200 | 200 | 0 | 0.917684 | 0.794272 | -0.123412 | 0.126786 | 0.149335 | 0.195897 | 0.191689 | -0.007957 | -0.199646 | 0.136002 | 0.169597 | 0.217393 | 0.11185 | -0.247299 | -0.35915 | 0.215021 | 0.278641 | 0.351959 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:20807243:C:G","position":20807... |
13:20908669:T:C | test | grch37 | 13 | T | C | GTEX | 42 | GTEx | 13:20908669:T:C:R:wC | 13:20908669:T:C:A:wC | ACAAAGGAGCACAACACCCTCTGTGTAGCTTCATCACAATGAGCGAGTAAACAACGTGCCTACAGTGACTATCCTGGTGCCTGCAACATCCCAGGCTCTTACCCCTACTGTCCCACACGCCCACCTCCCACTGCCACCACTGTTGCCCAAACTGAACAGGAACGAGCTGAGGGCCTCAGAGGGCACCAATCCAGTCCCCT | ACAAAGGAGCACAACACCCTCTGTGTAGCTTCATCACAATGAGCGAGTAAACAACGTGCCTACAGTGACTATCCTGGTGCCTGCAACATCCCAGGCTCTCACCCCTACTGTCCCACACGCCCACCTCCCACTGCCACCACTGTTGCCCAAACTGAACAGGAACGAGCTGAGGGCCTCAGAGGGCACCAATCCAGTCCCCT | 20,908,669 | 200 | 200 | 0 | -0.087412 | -0.582907 | -0.495495 | 0.316974 | 0.450627 | 0.550942 | 0.410435 | 0.633641 | 0.223205 | 0.254458 | 0.219675 | 0.336164 | -0.388339 | 0.309055 | 0.697394 | 0.472045 | 0.464856 | 0.662509 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:20908669:T:C","position":20908... |
13:21061969:C:A | test | grch37 | 13 | C | A | GTEX | 41 | GTEx | 13:21061969:C:A:R:wC | 13:21061969:C:A:A:wC | ATCACACTACTGAACTCCAGCCTGGGTGACAGAGCGAGACTCTATCTCAAAAAAAAACAAAAAACAAAAAGCAAAAAAAACTTAACTCATGCAGTTTACCGTGGCTCACGCCTGTAATCCCAGCACTTCGAGAGGCCAAGGCCAGCGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCTAACATGGTGAAACCCT | ATCACACTACTGAACTCCAGCCTGGGTGACAGAGCGAGACTCTATCTCAAAAAAAAACAAAAAACAAAAAGCAAAAAAAACTTAACTCATGCAGTTTACAGTGGCTCACGCCTGTAATCCCAGCACTTCGAGAGGCCAAGGCCAGCGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCTAACATGGTGAAACCCT | 21,061,969 | 200 | 200 | 0 | 0.616622 | -0.958843 | -1.575465 | 0.557555 | 0.684457 | 0.882808 | 0.163908 | 0.361955 | 0.198047 | 0.22381 | 0.216325 | 0.311268 | 0.442911 | 0.039334 | -0.403576 | 0.377657 | 0.327987 | 0.5002 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21061969:C:A","position":21061... |
13:21062640:T:C | test | grch37 | 13 | T | C | GTEX | 41 | GTEx | 13:21062640:T:C:R:wC | 13:21062640:T:C:A:wC | CTCCTTGTGTTCTGTTGTGACACACATTTGTTTAATGAATTTTTAGCAAATTGAGAATTTAACAATTTTAAGAAATTTTAGAGTCATAGAGACCTAAAATCTCCATCTTCTGTATTTGACCCGAATCTTAGAGCAGGAAATGACCAGAGAACACACACAGCCTTTTCGGTTTGCTTCCAAATTCTCAGCTAGAATATCAA | CTCCTTGTGTTCTGTTGTGACACACATTTGTTTAATGAATTTTTAGCAAATTGAGAATTTAACAATTTTAAGAAATTTTAGAGTCATAGAGACCTAAAACCTCCATCTTCTGTATTTGACCCGAATCTTAGAGCAGGAAATGACCAGAGAACACACACAGCCTTTTCGGTTTGCTTCCAAATTCTCAGCTAGAATATCAA | 21,062,640 | 200 | 200 | 0 | 0.587872 | 0.526115 | -0.061757 | 0.208386 | 0.162377 | 0.26418 | 0.665575 | 0.592601 | -0.072975 | 0.076009 | 0.068497 | 0.102319 | 1.010965 | 0.678721 | -0.332244 | 0.121069 | 0.124862 | 0.17392 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21062640:T:C","position":21062... |
13:21062677:G:C | test | grch37 | 13 | G | C | GTEX | 41 | GTEx | 13:21062677:G:C:R:wC | 13:21062677:G:C:A:wC | AATTTTTAGCAAATTGAGAATTTAACAATTTTAAGAAATTTTAGAGTCATAGAGACCTAAAATCTCCATCTTCTGTATTTGACCCGAATCTTAGAGCAGGAAATGACCAGAGAACACACACAGCCTTTTCGGTTTGCTTCCAAATTCTCAGCTAGAATATCAACAGAGTAACGACGTGAAATGTGCAAATCTCAGAACAC | AATTTTTAGCAAATTGAGAATTTAACAATTTTAAGAAATTTTAGAGTCATAGAGACCTAAAATCTCCATCTTCTGTATTTGACCCGAATCTTAGAGCAGCAAATGACCAGAGAACACACACAGCCTTTTCGGTTTGCTTCCAAATTCTCAGCTAGAATATCAACAGAGTAACGACGTGAAATGTGCAAATCTCAGAACAC | 21,062,677 | 200 | 200 | 0 | -0.474272 | -0.769524 | -0.295253 | 0.249927 | 0.246767 | 0.351222 | 0.106435 | -0.153964 | -0.260398 | 0.076834 | 0.091373 | 0.119384 | 0.522853 | 0.367261 | -0.155591 | 0.133492 | 0.115082 | 0.17625 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21062677:G:C","position":21062... |
13:21101016:C:T | test | grch37 | 13 | C | T | GTEX | 42 | GTEx | 13:21101016:C:T:R:wC | 13:21101016:C:T:A:wC | CATGCAACTTACACACAGTAGAAGGCAAGCTTAAATGTTGAGGACTTTTTGGAGGGAATGTTACAGTACATTGTTGAGACAGCCGCTAGCCTGAGCAACCGCGCCTGCTCTGGCTGAGAATACAAGGCTCCAAAGCTTCCATCTTCTGATGGAGCAGTTTCTGTAGTCAGTTACACAGGCAGCCAATATAATAATCAAGG | CATGCAACTTACACACAGTAGAAGGCAAGCTTAAATGTTGAGGACTTTTTGGAGGGAATGTTACAGTACATTGTTGAGACAGCCGCTAGCCTGAGCAACTGCGCCTGCTCTGGCTGAGAATACAAGGCTCCAAAGCTTCCATCTTCTGATGGAGCAGTTTCTGTAGTCAGTTACACAGGCAGCCAATATAATAATCAAGG | 21,101,016 | 200 | 200 | 0 | 0.067905 | 0.414442 | 0.346536 | 0.232451 | 0.181419 | 0.294867 | -0.226234 | 0.242949 | 0.469183 | 0.171792 | 0.146399 | 0.22571 | -0.152053 | 0.093014 | 0.245067 | 0.368889 | 0.299603 | 0.475227 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:21101016:C:T","position":21101... |
13:21141482:G:A | test | grch37 | 13 | G | A | GTEX | 42 | GTEx | 13:21141482:G:A:R:wC | 13:21141482:G:A:A:wC | CCCTCAGCGTGAGGTAGGAGAAGGGCGCTGGGGCCTAGTGCCTCAGGGCCCCTGGCAGCCGTGCCCCTGCGGCGTCCTGTGTGGCGCATCCCGCCGAGGGCCTCTTCGCCCGTCTCCTGCCCGCCCCTGTCGGCCCCGGGGCGGTCTGAGGCGGGGCCCCAGATGGACTCGGCCTGCCCCTGCTTTTCTTCCTCAGGCTC | CCCTCAGCGTGAGGTAGGAGAAGGGCGCTGGGGCCTAGTGCCTCAGGGCCCCTGGCAGCCGTGCCCCTGCGGCGTCCTGTGTGGCGCATCCCGCCGAGGACCTCTTCGCCCGTCTCCTGCCCGCCCCTGTCGGCCCCGGGGCGGTCTGAGGCGGGGCCCCAGATGGACTCGGCCTGCCCCTGCTTTTCTTCCTCAGGCTC | 21,141,482 | 200 | 200 | 0 | 3.174565 | 3.040354 | -0.13421 | 0.243766 | 0.268409 | 0.362582 | 2.512724 | 2.362305 | -0.150419 | 0.228103 | 0.194867 | 0.300007 | 3.773919 | 3.765041 | -0.008877 | 0.277663 | 0.261708 | 0.38156 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21141482:G:A","position":21141... |
13:21171621:C:T | test | grch37 | 13 | C | T | GTEX | 41 | GTEx | 13:21171621:C:T:R:wC | 13:21171621:C:T:A:wC | GATTACTGAGTGAGCTCAGAAGTTTGCGACCAGCCTGGGCAACATAGTGAGACCTCGTCTCTATTTATTAAAAAATATGTAGCCGGGTGCCGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACAAGGTCAGGAAATCGAGACCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAA | GATTACTGAGTGAGCTCAGAAGTTTGCGACCAGCCTGGGCAACATAGTGAGACCTCGTCTCTATTTATTAAAAAATATGTAGCCGGGTGCCGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACAAGGTCAGGAAATCGAGACCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAA | 21,171,621 | 200 | 200 | 0 | 0.923948 | 1.021116 | 0.097169 | 0.228394 | 0.264876 | 0.349747 | 0.666603 | 0.738592 | 0.071989 | 0.102774 | 0.104565 | 0.146616 | 0.846606 | 0.628094 | -0.218512 | 0.180404 | 0.191375 | 0.263001 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:21171621:C:T","position":21171... |
13:21216618:C:G | test | grch37 | 13 | C | G | GTEX | 42 | GTEx | 13:21216618:C:G:R:wC | 13:21216618:C:G:A:wC | GATCATTTGAAGTCAGGAGTTCGAGACCAGCCTGGCCATCATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTTGTGGCAGGCACCTGTAATCCCAGTTACTCCCGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATAGTGCCACTGTACTCCAGCCTA | GATCATTTGAAGTCAGGAGTTCGAGACCAGCCTGGCCATCATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTTGTGGCAGGCACGTGTAATCCCAGTTACTCCCGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATAGTGCCACTGTACTCCAGCCTA | 21,216,618 | 200 | 200 | 0 | 0.185741 | -0.191658 | -0.3774 | 0.255048 | 0.193027 | 0.319858 | -0.523868 | -0.660596 | -0.136728 | 0.186103 | 0.142056 | 0.234124 | -1.293989 | -0.641982 | 0.652007 | 0.464917 | 0.243105 | 0.524641 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:21216618:C:G","position":21216... |
13:21270132:C:A | test | grch37 | 13 | C | A | GTEX | 41 | GTEx | 13:21270132:C:A:R:wC | 13:21270132:C:A:A:wC | TGGATGGATTGAACAATGTACCAGACACAGCAGATGTCAGGATTAGTGAGTAGGTCAATAGAAAAATATCCAAACTAAAGCAAAGAGAAATAAGACTGGCAAAATAAAGCAGCTGACAAGAGACACTTGGGACACAGTCAAGAGTTTAAATAATTATAATGGGAATCCCGGAAGGAGTGGAAGAGAGAATAGGGTAGAAT | TGGATGGATTGAACAATGTACCAGACACAGCAGATGTCAGGATTAGTGAGTAGGTCAATAGAAAAATATCCAAACTAAAGCAAAGAGAAATAAGACTGGAAAAATAAAGCAGCTGACAAGAGACACTTGGGACACAGTCAAGAGTTTAAATAATTATAATGGGAATCCCGGAAGGAGTGGAAGAGAGAATAGGGTAGAAT | 21,270,132 | 200 | 200 | 0 | -0.158723 | -0.05593 | 0.102793 | 0.232008 | 0.276553 | 0.360984 | 0.175078 | 0.053386 | -0.121692 | 0.083114 | 0.082534 | 0.117131 | 0.256625 | 0.169794 | -0.086831 | 0.175205 | 0.139774 | 0.224129 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21270132:C:A","position":21270... |
13:21273755:A:G | test | grch37 | 13 | A | G | GTEX | 41 | GTEx | 13:21273755:A:G:R:wC | 13:21273755:A:G:A:wC | TCCTGCACCACATGACATCATTTCAGTCAAAAACAGACCACATATATGATGGTGGCCCCATACGATTATAATACCAAATTTTTACTGTACCTTTTCTATATTTAGATACACAAATACTTACTATTGTGTTACAATTGCCTACATTATGCAGTACAGTAACATGCTGTACAAGTTTGTAGCCTAGATGTGTTGTAGCCTAA | TCCTGCACCACATGACATCATTTCAGTCAAAAACAGACCACATATATGATGGTGGCCCCATACGATTATAATACCAAATTTTTACTGTACCTTTTCTATGTTTAGATACACAAATACTTACTATTGTGTTACAATTGCCTACATTATGCAGTACAGTAACATGCTGTACAAGTTTGTAGCCTAGATGTGTTGTAGCCTAA | 21,273,755 | 200 | 200 | 0 | 0.399522 | -0.191027 | -0.59055 | 0.324337 | 0.688392 | 0.760971 | -0.370365 | -0.302227 | 0.068137 | 0.123236 | 0.131862 | 0.180485 | -0.391873 | -0.986504 | -0.594631 | 0.221258 | 0.338475 | 0.404377 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:21273755:A:G","position":21273... |
13:21319200:A:G | test | grch37 | 13 | A | G | GTEX | 42 | GTEx | 13:21319200:A:G:R:wC | 13:21319200:A:G:A:wC | TTTTGTCAGGTTTGTCAAAGATCAGATGGTTGTAGATATGTGGTGTTATTTCTGAGATCTCTGTTCTGTTCCATTGGTCTATATATCTGTTTTGGCAACAGTGCCATGCTGTTTTGGTTACTAGCCTTGTAGTATAGTTTGAAGTCAGGTAGTGGATGCCTCCAGCTTTGTTCTTTTTGCTTAGGATTGTCTTGGCTATA | TTTTGTCAGGTTTGTCAAAGATCAGATGGTTGTAGATATGTGGTGTTATTTCTGAGATCTCTGTTCTGTTCCATTGGTCTATATATCTGTTTTGGCAACGGTGCCATGCTGTTTTGGTTACTAGCCTTGTAGTATAGTTTGAAGTCAGGTAGTGGATGCCTCCAGCTTTGTTCTTTTTGCTTAGGATTGTCTTGGCTATA | 21,319,200 | 200 | 200 | 0 | -0.015594 | -0.153115 | -0.137521 | 0.136184 | 0.126992 | 0.186207 | -0.108551 | 0.167755 | 0.276306 | 0.119439 | 0.110717 | 0.162862 | 0.127721 | 0.077585 | -0.050136 | 0.183553 | 0.2011 | 0.272273 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:21319200:A:G","position":21319... |
13:21330192:G:A | test | grch37 | 13 | G | A | GTEX | 42 | GTEx | 13:21330192:G:A:R:wC | 13:21330192:G:A:A:wC | TTGTTAGTTACAGAAGCATCAAGCTAGAAGGTAAACAGACATAAAGAAGGGAAACAGTGAGAAAGAGGCTTTAGAATAAGTGGAACATGTGGAATAAATGGAAATAAAAATGTTTATCACAGTTAGTTTCAAACAGGGTAAATAGGAAAAGTTTATATAACTCAGAGATCCAAACTAGACACAAAAATATTAAAGACTAT | TTGTTAGTTACAGAAGCATCAAGCTAGAAGGTAAACAGACATAAAGAAGGGAAACAGTGAGAAAGAGGCTTTAGAATAAGTGGAACATGTGGAATAAATAGAAATAAAAATGTTTATCACAGTTAGTTTCAAACAGGGTAAATAGGAAAAGTTTATATAACTCAGAGATCCAAACTAGACACAAAAATATTAAAGACTAT | 21,330,192 | 200 | 200 | 0 | 0.156064 | 1.251189 | 1.095125 | 0.455097 | 0.32252 | 0.557793 | -0.145321 | 1.059367 | 1.204688 | 0.287641 | 0.234405 | 0.371057 | -0.109788 | 0.829441 | 0.939229 | 0.529723 | 0.610229 | 0.808076 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21330192:G:A","position":21330... |
13:21340573:C:A | test | grch37 | 13 | C | A | GTEX | 42 | GTEx | 13:21340573:C:A:R:wC | 13:21340573:C:A:A:wC | GAAAAAAAGAAACATGTAATAGAAAAAATTAAACTCAACTGAAATGTCCAACCATTAGACAGTATATAATGTTGTATATTCCTACAGTATAAATATATTCACTACATAGCAGTGAAAACATTTTATGAATCTATTTCTTTCTCCATTGCTAGCTTACTAGCTGTGACTCTGTTATTTAAGAGGTTGCTTAAGAATTATGG | GAAAAAAAGAAACATGTAATAGAAAAAATTAAACTCAACTGAAATGTCCAACCATTAGACAGTATATAATGTTGTATATTCCTACAGTATAAATATATTAACTACATAGCAGTGAAAACATTTTATGAATCTATTTCTTTCTCCATTGCTAGCTTACTAGCTGTGACTCTGTTATTTAAGAGGTTGCTTAAGAATTATGG | 21,340,573 | 200 | 200 | 0 | 0.158354 | 0.93374 | 0.775386 | 0.421425 | 0.468811 | 0.630383 | 0.504579 | 0.135981 | -0.368598 | 0.195219 | 0.267601 | 0.331241 | -0.037972 | 0.629946 | 0.667918 | 0.502825 | 0.411234 | 0.649574 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21340573:C:A","position":21340... |
13:21366695:G:A | test | grch37 | 13 | G | A | GTEX | 42 | GTEx | 13:21366695:G:A:R:wC | 13:21366695:G:A:A:wC | TACTTGGGAGGCTGAGGGAGGAAAATCACTTGAACCGAGGAGGCAGAGGTTGCAGTGAGCCAAGATGGCGCCACCGCAGTCCAGCCTGGGTGACAGAGCGAGACGCTGTCTCAAAAACAAACAAACAAATAAACAAACAAATTAGCCAGGCCTGGTGGCGGGTTCCTATAATCCCAGCTACTCGTAAGGCTGAGGTGGAG | TACTTGGGAGGCTGAGGGAGGAAAATCACTTGAACCGAGGAGGCAGAGGTTGCAGTGAGCCAAGATGGCGCCACCGCAGTCCAGCCTGGGTGACAGAGCAAGACGCTGTCTCAAAAACAAACAAACAAATAAACAAACAAATTAGCCAGGCCTGGTGGCGGGTTCCTATAATCCCAGCTACTCGTAAGGCTGAGGTGGAG | 21,366,695 | 200 | 200 | 0 | 0.796783 | 0.706813 | -0.08997 | 0.152555 | 0.225785 | 0.272492 | 1.424194 | 1.253805 | -0.170389 | 0.102312 | 0.140136 | 0.17351 | 1.106505 | 0.975222 | -0.131283 | 0.213466 | 0.253157 | 0.331144 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21366695:G:A","position":21366... |
13:21369057:C:CA | test | grch37 | 13 | C | CA | GTEX | 42 | GTEx | 13:21369057:C:CA:R:wC | 13:21369057:C:CA:A:wC | GGCTGGGCCTAAAAACAGACCAGAAAGAATTCACTGAGGAAAAGTGAATTTGTACAGTGCTTTTCAGACTATCTCACCTTGGTACCCCTAGTTAACTGCAAAAAAAATAAAGAGTAAACCTTCTACACTGTGAAGTTGATGGTACCTAGCTCAGGGCAGATATTGGAAAAACCGTTGCCCAAGAATTTAAAAAAAAAAA | GGCTGGGCCTAAAAACAGACCAGAAAGAATTCACTGAGGAAAAGTGAATTTGTACAGTGCTTTTCAGACTATCTCACCTTGGTACCCCTAGTTAACTGCAAAAAAAAATAAAGAGTAAACCTTCTACACTGTGAAGTTGATGGTACCTAGCTCAGGGCAGATATTGGAAAAACCGTTGCCCAAGAATTTAAAAAAAAAAA | 21,369,057 | 199 | 200 | 1 | 0.313841 | 0.271803 | -0.042038 | 0.299337 | 0.411414 | 0.508787 | 0.117154 | -0.216778 | -0.333932 | 0.179857 | 0.276775 | 0.33008 | -0.133918 | -0.110212 | 0.023706 | 0.349863 | 0.499967 | 0.610222 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Insert, 99, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"CA","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Insert","local_position_one_based":99,"new_sequence":"A","pair_id":"13:21369057:C:CA","position":21369057... |
13:21388078:C:T | test | grch37 | 13 | C | T | GTEX | 42 | GTEx | 13:21388078:C:T:R:wC | 13:21388078:C:T:A:wC | TCCACCTACTCAGGAGACTGAGGCAGAAGAATCGCTTAAACCCGGGAGGCAGAAGTTGCTGTGAGCCAATATTACGCCACTGCACTTCAGCTTGGGTGACAGAGCAAGACGCTGTCTCAAAAAAAAAAAAAAAAAATCTATTGAACGCTAAGAGCCAGGCACTGGAATATGGAGATGAATAAGATACTTTCTTTCCATAG | TCCACCTACTCAGGAGACTGAGGCAGAAGAATCGCTTAAACCCGGGAGGCAGAAGTTGCTGTGAGCCAATATTACGCCACTGCACTTCAGCTTGGGTGATAGAGCAAGACGCTGTCTCAAAAAAAAAAAAAAAAAATCTATTGAACGCTAAGAGCCAGGCACTGGAATATGGAGATGAATAAGATACTTTCTTTCCATAG | 21,388,078 | 200 | 200 | 0 | -0.119051 | -0.455834 | -0.336783 | 0.295744 | 0.338453 | 0.449461 | -0.231362 | -0.301868 | -0.070506 | 0.207699 | 0.19657 | 0.28597 | -0.126988 | 0.412851 | 0.539839 | 0.368071 | 0.328682 | 0.493465 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:21388078:C:T","position":21388... |
13:21392846:T:C | test | grch37 | 13 | T | C | GTEX | 42 | GTEx | 13:21392846:T:C:R:wC | 13:21392846:T:C:A:wC | TACAATTATAAAAATCATTTAAAAAATAATTTTAAAAAATTAGAATTATAATTAGTTTGCACCAAACAAAACTCAACAGTTGTTCTTATGTGGTAAGAGTGCACACAGGTTTTCAATAAAAGCTATTATTTTAAAGGCTCATTTTAAAAAATTATTCTACATGTTATTGCTTGTAATAAATTATTGTACACTATACACGT | TACAATTATAAAAATCATTTAAAAAATAATTTTAAAAAATTAGAATTATAATTAGTTTGCACCAAACAAAACTCAACAGTTGTTCTTATGTGGTAAGAGCGCACACAGGTTTTCAATAAAAGCTATTATTTTAAAGGCTCATTTTAAAAAATTATTCTACATGTTATTGCTTGTAATAAATTATTGTACACTATACACGT | 21,392,846 | 200 | 200 | 0 | 1.426356 | 1.272785 | -0.153571 | 0.433067 | 0.401044 | 0.59024 | 1.063436 | 1.053719 | -0.009717 | 0.210373 | 0.216867 | 0.30214 | 1.066256 | 1.176139 | 0.109884 | 0.395661 | 0.415396 | 0.573673 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21392846:T:C","position":21392... |
13:21397257:T:C | test | grch37 | 13 | T | C | GTEX | 42 | GTEx | 13:21397257:T:C:R:wC | 13:21397257:T:C:A:wC | ATAGTATTAATATTCTCAGATGTTAAAGGTTTCATTTCTGTAATCTGACATATTAGAGCCAAGGAAAATTTAGTGAAGGAATATGATCATTATTAATCTTAATCCATCCAACACTTACTGTTGGATGTACCATTTTGTACTTGCCGAAGTACTTAACTAGCCCTTTTCTTTCCCACACAAAGTTCTCTCTCTATTTTGTA | ATAGTATTAATATTCTCAGATGTTAAAGGTTTCATTTCTGTAATCTGACATATTAGAGCCAAGGAAAATTTAGTGAAGGAATATGATCATTATTAATCTCAATCCATCCAACACTTACTGTTGGATGTACCATTTTGTACTTGCCGAAGTACTTAACTAGCCCTTTTCTTTCCCACACAAAGTTCTCTCTCTATTTTGTA | 21,397,257 | 200 | 200 | 0 | 0.250588 | 0.344865 | 0.094277 | 0.17507 | 0.208845 | 0.272517 | 0.261266 | 0.038521 | -0.222746 | 0.160323 | 0.161494 | 0.22756 | 0.421756 | 0.337366 | -0.08439 | 0.226563 | 0.245439 | 0.334023 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21397257:T:C","position":21397... |
13:21544585:C:T | test | grch37 | 13 | C | T | UKBB | 30 | SBP | 13:21544585:C:T:R:wC | 13:21544585:C:T:A:wC | TTCAGGCGATCCGCCTGCCTCAGCCCCACAAAGTGCTGGGATTACAGGCATGACACATGGTGCCTGGCCTTCCCTACTTTTACAAGGCAATAAGTTAGCCTGTTCTTTAGTGGAGTGGTCCCCAACCTTTTTGGCACCAGGGACCAGTTTTGTGGAAGACAATTTTTCCATGGACGGGGAAGGGATGGTTTCAGGATGAA | TTCAGGCGATCCGCCTGCCTCAGCCCCACAAAGTGCTGGGATTACAGGCATGACACATGGTGCCTGGCCTTCCCTACTTTTACAAGGCAATAAGTTAGCTTGTTCTTTAGTGGAGTGGTCCCCAACCTTTTTGGCACCAGGGACCAGTTTTGTGGAAGACAATTTTTCCATGGACGGGGAAGGGATGGTTTCAGGATGAA | 21,544,585 | 200 | 200 | 0 | 0.024345 | -0.084958 | -0.109302 | 0.165738 | 0.126159 | 0.208291 | -0.209356 | -0.231974 | -0.022618 | 0.125859 | 0.125617 | 0.177821 | -0.296792 | -0.379427 | -0.082635 | 0.103047 | 0.096354 | 0.141077 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:21544585:C:T","position":21544... |
13:21545651:T:C | test | grch37 | 13 | T | C | UKBB | 30 | SBP | 13:21545651:T:C:R:wC | 13:21545651:T:C:A:wC | TATATAGAGTGCCAAGAAATATTGTCAAGTGAAGAAAACAAATGCAGAAAAATATGCATAATATTCCCTCATTTCTGTAAGAGGCAAAAGGTACACATATATATTTTTTCTTGTACATAAACTTTCATTCCTCTAAGAATGCCCAGTATATTGTTAATAATATCATTTGTTGTCTGTGGGGAGGTGAATTGAATGACTGG | TATATAGAGTGCCAAGAAATATTGTCAAGTGAAGAAAACAAATGCAGAAAAATATGCATAATATTCCCTCATTTCTGTAAGAGGCAAAAGGTACACATACATATTTTTTCTTGTACATAAACTTTCATTCCTCTAAGAATGCCCAGTATATTGTTAATAATATCATTTGTTGTCTGTGGGGAGGTGAATTGAATGACTGG | 21,545,651 | 200 | 200 | 0 | -0.113107 | -0.082123 | 0.030984 | 0.12172 | 0.141248 | 0.186458 | -0.327201 | -0.259055 | 0.068146 | 0.116624 | 0.13057 | 0.17507 | -0.369263 | -0.263575 | 0.105687 | 0.094793 | 0.096842 | 0.135514 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21545651:T:C","position":21545... |
13:21558264:C:T | test | grch37 | 13 | C | T | UKBB | 30 | SBP | 13:21558264:C:T:R:wC | 13:21558264:C:T:A:wC | GTTCCAGCGATTCTGCTGTCTCAGCCTCCCGAGTAGCTGGGACTACATGTGCCCGCCACCATGACACCTGGCTAATTTTTGTATTTTTAGTAGAAACAGCGTTTCATCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCAGGGATTACAGGCTTGAGCCACTGT | GTTCCAGCGATTCTGCTGTCTCAGCCTCCCGAGTAGCTGGGACTACATGTGCCCGCCACCATGACACCTGGCTAATTTTTGTATTTTTAGTAGAAACAGTGTTTCATCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCAGGGATTACAGGCTTGAGCCACTGT | 21,558,264 | 200 | 200 | 0 | 0.096016 | -0.044223 | -0.140239 | 0.117669 | 0.143429 | 0.185521 | -0.003893 | 0.092068 | 0.095961 | 0.115207 | 0.099561 | 0.152266 | -0.869607 | -0.80112 | 0.068487 | 0.106091 | 0.135683 | 0.172236 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"T","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"T","pair_id":"13:21558264:C:T","position":21558... |
13:21558810:A:G | test | grch37 | 13 | A | G | GTEX | 41 | GTEx | 13:21558810:A:G:R:wC | 13:21558810:A:G:A:wC | TGCCATTTACAACAGCTATAAAAAAAATCTAGGAGTAAATTTAACCAAAAAGTGAAAGAGCTCTACAAAGAAAACTACAAAACACTGAAGAAAGAAACTAAAGAGGACACAAACAAATGAAAAGAGATCCCATGTTCACCGACAGAAAGATTTAATATTGTTAAAATGACCATACTACCCAAATCAATCTACCAATTAAA | TGCCATTTACAACAGCTATAAAAAAAATCTAGGAGTAAATTTAACCAAAAAGTGAAAGAGCTCTACAAAGAAAACTACAAAACACTGAAGAAAGAAACTGAAGAGGACACAAACAAATGAAAAGAGATCCCATGTTCACCGACAGAAAGATTTAATATTGTTAAAATGACCATACTACCCAAATCAATCTACCAATTAAA | 21,558,810 | 200 | 200 | 0 | -0.255621 | 0.180526 | 0.436147 | 0.298826 | 0.312062 | 0.432065 | 0.000805 | -0.148938 | -0.149742 | 0.124114 | 0.131483 | 0.18081 | 0.34686 | 0.285982 | -0.060877 | 0.161449 | 0.211829 | 0.26634 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"GTEX","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:21558810:A:G","position":21558... |
13:21560021:C:CT | test | grch37 | 13 | C | CT | UKBB | 30 | SBP | 13:21560021:C:CT:R:wC | 13:21560021:C:CT:A:wC | ACCTGTAATCCCAGCACCCTGGGAGGCTGAGACAGGTGGATCATCTGAGGTCGGAAGTTTGAGACCAGCCTGAACAACATGGTGAAACCCTGTCTCTACAAAAACATAAAACTAGCTGGGCGTGGTGGTGCATGCCTGTAATCCCAGCTGCTCGGTAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTT | ACCTGTAATCCCAGCACCCTGGGAGGCTGAGACAGGTGGATCATCTGAGGTCGGAAGTTTGAGACCAGCCTGAACAACATGGTGAAACCCTGTCTCTACTAAAAACATAAAACTAGCTGGGCGTGGTGGTGCATGCCTGTAATCCCAGCTGCTCGGTAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTT | 21,560,021 | 199 | 200 | 1 | -0.075077 | -0.13009 | -0.055013 | 0.20481 | 0.248278 | 0.321852 | 0.203923 | 0.131183 | -0.072739 | 0.155068 | 0.175758 | 0.234386 | 0.227563 | 0.180897 | -0.046666 | 0.132653 | 0.143767 | 0.195616 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Insert, 99, T | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"CT","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Insert","local_position_one_based":99,"new_sequence":"T","pair_id":"13:21560021:C:CT","position":21560021... |
13:21566464:G:A | test | grch37 | 13 | G | A | UKBB | 30 | SBP | 13:21566464:G:A:R:wC | 13:21566464:G:A:A:wC | GCCCATGGCAGCAGCACGCAAGGGTAGGTGGAGATGGGGGGATGGACCCACAGATGGGGGCCAGGCTCTCCAGGGTTTTGCTCCTGTCTGCAGGCATTCGAGGAAGCTTTCAAACTGGGACATACGGCATCAGCAGGTCAGGCTGGGGGCGGCTGTGGGTGCAGAGCTGGAGGCACTCAGATGGGGGAGACAGAATAGGC | GCCCATGGCAGCAGCACGCAAGGGTAGGTGGAGATGGGGGGATGGACCCACAGATGGGGGCCAGGCTCTCCAGGGTTTTGCTCCTGTCTGCAGGCATTCAAGGAAGCTTTCAAACTGGGACATACGGCATCAGCAGGTCAGGCTGGGGGCGGCTGTGGGTGCAGAGCTGGAGGCACTCAGATGGGGGAGACAGAATAGGC | 21,566,464 | 200 | 200 | 0 | 0.54547 | 0.506021 | -0.039449 | 0.122729 | 0.118026 | 0.170272 | 0.547387 | 0.744472 | 0.197085 | 0.099045 | 0.116603 | 0.15299 | 0.653185 | 0.518374 | -0.13481 | 0.077433 | 0.083096 | 0.113582 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, A | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"A","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"A","pair_id":"13:21566464:G:A","position":21566... |
13:21569227:T:C | test | grch37 | 13 | T | C | UKBB | 30 | SBP | 13:21569227:T:C:R:wC | 13:21569227:T:C:A:wC | AGGGAGGCCACACACCTAGGTTCACCCCTCCCCTCTGCTGCTTAGCAGCTGTGTAACTTTCAGCAAATCATTTCCTTACTTTGAGTGCCCGTTTCCTCATCTGGGAAATAAGGCTAATAGGTTGCTCTAGGGATGAAAGGAGATGTCATGCTTGGGCATCAGCATCACTTAAGGGTTAGCTGTTACAGTTCACAAAGGTA | AGGGAGGCCACACACCTAGGTTCACCCCTCCCCTCTGCTGCTTAGCAGCTGTGTAACTTTCAGCAAATCATTTCCTTACTTTGAGTGCCCGTTTCCTCACCTGGGAAATAAGGCTAATAGGTTGCTCTAGGGATGAAAGGAGATGTCATGCTTGGGCATCAGCATCACTTAAGGGTTAGCTGTTACAGTTCACAAAGGTA | 21,569,227 | 200 | 200 | 0 | -0.428922 | -0.126925 | 0.301997 | 0.293235 | 0.286954 | 0.41028 | -0.123401 | -0.342025 | -0.218623 | 0.204199 | 0.221882 | 0.301544 | -1.337649 | -1.067736 | 0.269914 | 0.242812 | 0.250723 | 0.349027 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, C | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"C","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"C","pair_id":"13:21569227:T:C","position":21569... |
13:21569589:T:G | test | grch37 | 13 | T | G | UKBB | 30 | SBP | 13:21569589:T:G:R:wC | 13:21569589:T:G:A:wC | GTCTCTTCCAGCTTACCTCAGGCTGCTGTGTAAACATTATCCACGTCTATGCATGCCAAGATGTGGAAAGGGTGAGCAGCCCTGCCCCAAAGCAAGAGTTCAGCTGCAAGCCAACTGAAGGCGAGGACAGTTCAGGTATGTGTTCTGGTGTCTAGCGTGTAGAAAGAGATCAGCAGATATCTGTTCAATGAATGATTGAG | GTCTCTTCCAGCTTACCTCAGGCTGCTGTGTAAACATTATCCACGTCTATGCATGCCAAGATGTGGAAAGGGTGAGCAGCCCTGCCCCAAAGCAAGAGTGCAGCTGCAAGCCAACTGAAGGCGAGGACAGTTCAGGTATGTGTTCTGGTGTCTAGCGTGTAGAAAGAGATCAGCAGATATCTGTTCAATGAATGATTGAG | 21,569,589 | 200 | 200 | 0 | 0.191825 | 0.015012 | -0.176813 | 0.112014 | 0.129591 | 0.171293 | -0.319267 | -0.439489 | -0.120222 | 0.110295 | 0.112287 | 0.157396 | -0.585153 | -0.568331 | 0.016822 | 0.100076 | 0.108864 | 0.147873 | goal_conditioned_mpra_local_edit_design | Gosai_2024_MPRA_GRCh37_simple_wC | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new base or inserted sequence. For an insertio... | Substitute, 100, G | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | [
{
"role": "user",
"content": "Identify the local DNA edit that produces the requested MPRA activity changes relative to the reference DNA. Activity changes are alternate minus reference log2FC. Predict whether the edit is a substitution or insertion, its one-based position in the reference DNA, and the new ... | {"alternate_allele":"G","alternate_sequence_length":200,"answer_mode":"no-cot","assembly":"grch37","chromosome":"13","completion_format":"<Edit Type>, <Position>, <New Sequence>","data_project":"UKBB","edit_type":"Substitute","local_position_one_based":100,"new_sequence":"G","pair_id":"13:21569589:T:G","position":21569... |
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