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NCT02553642 | 33:53:treatment | The lesion being considered for palliative radiation is not a target lesion | {
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NCT02508038 | 6:14:chronic_disease | RPR (Syphilis TP) | {
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NCT01953900 | 7:32:chronic_disease | Known primary immune deficiency | {
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NCT02056470 | 20:35:treatment | Patients requiring knee prosthesis | {
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NCT02064296 | 8:41:treatment,43:49:treatment,71:79:treatment | Use of over the counter pain medications (NSAIDs, etc.) on the day of MRI scan | {
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NCT02986087 | 1:16:chronic_disease | placenta previa | {
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NCT02251431 | 1:24:treatment | Prior bariatric surgery | {
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NCT01494324 | 30:58:cancer | Patients with diagnosed with secondary hepatic malignancy | {
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NCT02516332 | 1:16:chronic_disease | Unstable angina | {
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NCT03132415 | 1:4:chronic_disease | HIV-positive | {
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NCT02945800 | 36:48:cancer,50:63:cancer,68:84:cancer,92:128:cancer | have had a histologic diagnosis of osteosarcoma, Ewing sarcoma, or rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma either at diagnosis or relapse | {
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NCT01690468 | 20:38:cancer | platinum-resistant epithelial ovarian | {
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NCT02236000 | ,45:53:chronic_disease | Persistent greater than or equal to grade 2 diarrhea regardless of etiology | {
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NCT02781103 | 1:20:chronic_disease | Parkinson's Disease | {
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NCT02276443 | 18:33:cancer,,78:95:cancer,151:156:cancer,161:196:cancer | Prior history of invasive cancer within 5 years of study entry or history of metastatic cancer; exceptions include non-metastatic, curatively treated basal and squamous cell carcinoma of the skin | {
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NCT02554383 | 1:17:chronic_disease | Immunodeficiency | {
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NCT02138214 | 9:36:cancer, | Largest papillary thyroid carcinoma < 1 cm in size on ultrasound | {
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NCT02452008 | 31:36:cancer,37:43:treatment,87:96:treatment,118:126:treatment | Patients acceptance to have a tumor biopsy of an accessible lesion at baseline and on treatment if the lesion can be biopsied with acceptable clinical risk (as judged by the investigator) | {
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NCT03120585 | 1:27:chronic_disease,31:63:chronic_disease,67:83:chronic_disease | Neonates with hypoglycemia or clinical evidence of dehydration or volume depletion requiring fluid bolus | {
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NCT02781103 | 12:27:chronic_disease | History of Hunner's lesion in the medical record | {
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NCT02639065 | 12:49:chronic_disease | History of psychiatric illness/social situations that would limit compliance with study requirements or compromise the ability of the subject to give written informed consent | {
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NCT01228448 | 28:32:cancer,37:41:cancer,47:64:cancer,96:108:treatment | Adult subjects with brain, head and neck, and skull base tumors receiving external beam proton radiotherapy at the Francis H. Burr Proton Therapy Center at MGH | {
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NCT02365467 | 16:26:chronic_disease,28:36:chronic_disease,41:56:chronic_disease | Subject has an aneurysmal, tortuous, or atherosclerotic LSA | {
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NCT02253316 | ,,,33:57:chronic_disease | uncompensated NYHA Class 3 or 4 congestive heart failure | {
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NCT01313533 | ,44:79:treatment | Any patient was has undergone more than 20 computerized tomography (CAT) scans | {
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NCT02233868 | 1:11:treatment,24:33:treatment,37:40:chronic_disease,61:64:treatment,80:89:treatment,91:102:treatment,104:115:treatment,117:129:treatment,132:143:treatment,170:186:treatment,201:216:treatment,241:268:treatment,270:289:treatment,295:323:treatment,326:333:treatment,335:342:treatment,344:360:treatment,362:380:treatment,49... | antivirals (except for treatment of HSV with agents without CNS activity, e.g. acyclovir, ganciclovir, famciclovir, valacyclovir); anxiolytics; cough/cold preparations (dextromethorphan preparations, pseudoephedrine); hormones (exceptions: thyroid hormone replacement, oral contraceptives, and estrogen replacement thera... | {
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NCT01681264 | 7:17:treatment, | Takes vitamin B2 > 1.6mg/day during the study | {
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NCT02418195 | 1:21:chronic_disease | Polyarteritis nodosa | {
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NCT00258427 | 1:16:chronic_disease,,,,,,, | Aplastic anemia is defined as having at least one of the following (with or without cytogenetic abnormalities): platelet count <20 * 10^9, - absolute neutrophil count (ANC) <5 * 10^8/L, - Hgb <8 g/dL / | {
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NCT02237183 | 29:43:treatment,67:74:treatment,84:127:treatment | patients must not be taking anticoagulants, with the exception of aspirin or other non-steroidal anti-inflammatory medications | {
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NCT02833207 | 26:53:chronic_disease | Self-reported history of peripheral vascular disease | {
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NCT02446093 | 36:48:chronic_disease | Evidence of clinically significant pancreatitis as determined by the investigator | {
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NCT02531295 | ,,37:40:chronic_disease | Pre-ART viral load <2000 copies/ml (HIV controllers) | {
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NCT02536794 | 12:44:chronic_disease | History of primary immunodeficiency disease | {
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NCT03091790 | 28:49:treatment | Patient scheduled for open ventral hernia repair at LBJ General Hospital | {
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NCT02512926 | 1:9:cancer | Lymphoma patients are permitted | {
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NCT02352454 | 1:6:chronic_disease,46:54:chronic_disease,56:66:chronic_disease,79:89:chronic_disease,91:116:chronic_disease | Ulcer not of VLU pathophysiology (e.g., pure diabetic, vasculitic, radiation, rheumatoid, collagen vascular disease, pressure, or arterial etiology) | {
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NCT02339233 | 1:14:chronic_disease | pressure sore that might interfere with training | {
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NCT03034564 | 14:33:chronic_disease | Diagnosis of Parkinson's Disease | {
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NCT02508038 | 57:76:treatment | Is free from communicable disease risks associated with xenotransplantation | {
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NCT00902720 | 1:10:treatment,19:28:treatment,69:79:cancer | radiation for the treatment or prevention of a medical condition or malignancy expected to result in permanent and complete loss of subsequent ovarian function or have a medical condition or malignancy that requires removal of all or part of one or both ovaries | {
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NCT03114020 | 18:33:chronic_disease | Individuals with PiMZ deficiency are not allowed in the study | {
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NCT01597518 | 21:29:allergy_name | Hypersensitivity to riluzole or any of its components | {
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NCT03187951 | 1:22:cancer | Neuroendocrine cancer | {
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NCT00904046 | 15:45:chronic_disease | Subjects with uric acid kidney stone disease | {
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NCT02944825 | 1:28:treatment | shockwave lithotripsy [SWL] | {
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NCT02776761 | 5:20:treatment,, | For corticosteroids, this will mean prednisone, or equivalent, greater than or equal to 0.5 mg/kg/day | {
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NCT02122328 | 11:15:chronic_disease | Confirmed TTTS patients | {
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NCT01877382 | 1:28:treatment,32:43:treatment,,72:86:treatment | treatment with nitrosoureas or mitomycin C within 6 weeks before study drug treatment | {
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NCT02928991 | 1:29:chronic_disease | Congenital Dyserythropoietic | {
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NCT02439450 | 1:35:chronic_disease | Significant cardiovascular disease | {
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NCT01618357 | 34:41:chronic_disease,45:64:chronic_disease,116:125:treatment | Patients must not have a serious medical or psychiatric illness which prevents informed consent or compliance with treatment | {
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NCT02290951 | 52:64:allergy_name | History of hypersensitivity to any compound in the tetracycline antibiotics group | {
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NCT02496585 | 9:18:treatment,24:36:treatment,48:57:treatment,61:81:treatment,91:101:cancer | Ongoing treatment with radiotherapy to thorax, cytotoxic or biological therapies for this malignancy | {
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NCT02566304 | 55:65:cancer | Active involvement of the central nervous system with malignancy | {
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NCT02393690 | 35:53:chronic_disease | For patients with non-measurable, structural disease | {
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NCT02132598 | 32:43:chronic_disease | Any history of congenital long QT syndrome | {
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NCT01695967 | 1:39:chronic_disease | congenital head and neck malformations | {
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NCT02332928 | 1:14:chronic_disease,, | hypercalcemia (calcium >11 mg/dL) Ca = SerumCa + 0.8 * (NormalAlbumin - PatientAlbumin) | {
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NCT02974686 | 36:58:treatment | Dual organ or kidney after another solid organ transplant | {
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NCT02857218 | 12:28:chronic_disease | ongoing or active infection | {
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NCT01341080 | 1:16:chronic_disease,28:46:treatment,102:109:treatment, | Serious illness (requiring systemic treatment/or hospitalization) until the subject either completes therapy or is clinically stable on therapy, in the opinion of the site investigator, for at least 60 days prior to study entry | {
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NCT02339233 | 1:4:chronic_disease,8:12:chronic_disease,21:28:chronic_disease | HIV or AIDS related illness | {
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NCT02385110 | 47:50:chronic_disease, | We have seen an increasing number of cases of HLH at our institution over the last 2 years partly due to referrals and partly due to better understanding of the disease through discussions with our collaborators Dr Kenneth McClain and Dr Carl Allen at TCH (experts in pediatric HLH) | {
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NCT02106988 | 13:16:chronic_disease | known to be HIV positive | {
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NCT02562755 | 1:25:chronic_disease, | congestive heart failure within the preceding 12 months | {
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NCT02763228 | 26:39:cancer | Pathologically confirmed breast cancer | {
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NCT02474667 | 21:49:chronic_disease | History of positive human immunodeficiency virus test | {
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NCT02574728 | 57:67:cancer | Participants must have had a histologic verification of malignancy at original diagnosis or relapse | {
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NCT02178709 | ,,,149:158:treatment | WOCBP and men must agree to use adequate contraception prior, to study entry, for the duration of study participation, and 8 weeks after the end of treatment | {
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NCT02751866 | 1:9:chronic_disease | diabetes | {
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NCT01851369 | 1:4:chronic_disease,26:60:treatment,117:123:treatment | HIV-positive patients on combination antiretroviral therapy are ineligible because of possible PK interactions with TRC102 | {
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NCT02496663 | 96:105:treatment,107:118:treatment,122:140:treatment,172:178:treatment, | Patients currently receiving (or unable to stop use prior to receiving the first dose of study treatment) medications or herbal supplements known to be potent inducers of CYP3A4 (at least 3 weeks prior) | {
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NCT01943851 | 67:77:treatment | This method must be used from the time of the first dose of study medication until 16 weeks after the last dose of study medication | {
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NCT02565901 | 10:20:cancer | No prior malignancy | {
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NCT02124772 | 33:67:treatment,75:89:treatment,91:101:treatment,113:126:treatment,135:182:treatment | Part B, Part C and Part D only: Previous treatment with dabrafenib or any BRAF inhibitor, trametinib or another MEK inhibitor, or and Extracellular signal-regulated kinase inhibitor | {
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NCT02516670 | 24:47:treatment,49:56:treatment,61:106:treatment | Are being treated with anticoagulation therapy (aspirin and nonsteroidal anti-inflammatory drugs [NSAIDS] are allowed) | {
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NCT01893554 | 75:84:treatment | Subjects with clinically insignificant cardiac abnormalities requiring no treatment may be enrolled | {
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NCT02132598 | ,99:108:treatment | Patients must have normal organ and marrow function as defined below: (within 4 days of beginning treatment unless noted otherwise) | {
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NCT01959698 | 65:78:treatment,80:97:treatment,99:111:treatment,116:129:treatment | Patients must not have any significant toxicity associated with prior surgery, radiation therapy, chemotherapy, or immunotherapy, per principal investigator (PI) discretion | {
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NCT02725177 | ,,,,,,,,,,,326:335:treatment | Women of childbearing potential must be using adequate birth control measures (abstinence, hormonal contraceptives, intrauterine device, barrier method with spermicide, or surgical sterilization) and must agree to continue such precautions, and not become pregnant or plan a pregnancy for 6 months after receiving their ... | {
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NCT02498613 | ,,53:61:treatment,66:75:treatment,248:257:treatment | Pregnant women are excluded from this study because olaparib and cediranib have the potential for teratogenic or abortifacient effects; due to the fact that there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with olaparib and cediranib, breastfeeding should... | {
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NCT02172651 | 27:39:treatment,43:55:treatment,,,84:95:treatment,100:115:treatment | Participants who have had chemotherapy or radiotherapy within 4 weeks (6 weeks for bevacizumab) of liver resection | {
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NCT02194738 | 21:47:cancer | Completely resected non-small cell lung cancer with negative margins (R0) | {
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NCT01681589 | 39:64:chronic_disease,66:99:chronic_disease,114:134:chronic_disease,143:154:chronic_disease,162:168:chronic_disease,170:178:chronic_disease,182:203:chronic_disease | Complicating medical problems such as uncontrolled hypertension, diabetes with signs of neuropathy, and previous neurological illness such as head trauma, prior stroke, epilepsy or demyelinating disease, implanted neuromodulatory or electronic device, metal in head | {
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NCT02967315 | 15:23:chronic_disease | Patients with diabetes | {
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NCT01280669 | 15:32:chronic_disease,25:32:chronic_disease,51:85:treatment,93:105:treatment,107:119:treatment,121:137:treatment,139:151:treatment,153:166:treatment,167:174:treatment,176:186:treatment,191:203:treatment,216:226:treatment,236:251:treatment,260:269:treatment,378:402:treatment | Patients with bilateral uveitis who are receiving systemic immunosuppressive therapy (e.g., methotrexate, cyclosporine, cyclophosphamide, chlorambucil, mycophenolate mofetil, tacrolimus, or azathioprine) other than prednisone or other corticosteroids for the treatment of uveitis and the uveitis in the fellow eye, in th... | {
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NCT02162420 | 1:21:cancer,,,, | Refractory cytopenia defined by bone marrow cellularity <50% (with < 30% residual hematopoietic cells) | {
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NCT02102113 | 27:49:chronic_disease | Current or lifetime major DSM-IV Axis I disorder | {
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NCT01333046 | ,,88:105:treatment | Pulse oximetry of more than 95 percent on room air in patients who previously received radiation therapy | {
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NCT00872950 | 14:25:chronic_disease | No prolonged QT syndrome as indicated by baseline EKG | {
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NCT03016351 | 12:59:chronic_disease | History of cardiovascular disease or cardiovascular events | {
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"History",
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NCT03145298 | 12:22:cancer, | History of malignancy within the last 5 years | {
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"cancer": "malignancy",
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NCT02237183 | 45:53:treatment | participants on the placebo arm of previous iloprost trials | {
"allergy_name": null,
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"treatment": "iloprost"
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"participants",
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] | 2,942 |
NCT01174108 | 1:23:chronic_disease,27:35:chronic_disease,65:76:treatment,95:106:chronic_disease | Refractory anemia (RA) or RARS MDS patients who have associated transfusion dependence and/or neutropenia | {
"allergy_name": null,
"cancer": null,
"chronic_disease": "neutropenia",
"treatment": "transfusion"
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