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7.13k
NCT02446886
13:34:chronic_disease,46:50:chronic_disease,54:58:chronic_disease
Progressive neurological disorder other than RRMS or SPMS
{ "allergy_name": null, "cancer": null, "chronic_disease": "Left or right ventricular aneurysm", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Progressive", "neurological", "disorder", "other", "than", "RRMS", "or", "SPMS" ]
null
NCT01989507
49:69:treatment
actively quitting smoking or current use of any nicotine replacement or other smoking cessation treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": "cardiopulmonary", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1 ]
[ "actively", "quitting", "smoking", "or", "current", "use", "of", "any", "nicotine", "replacement", "or", "other", "smoking", "cessation", "treatment" ]
null
NCT02667418
1:11:treatment
vancomycin
{ "allergy_name": null, "cancer": null, "chronic_disease": "constrictive pericarditis", "treatment": null }
[ 0 ]
[ "vancomycin" ]
null
NCT02354703
114:125:treatment
As of Screen Visit, the subject is sharing a household with a subject randomized to any investigational trial of ondansetron
{ "allergy_name": null, "cancer": null, "chronic_disease": "Pulmonary hypertension", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "As", "of", "Screen", "Visit,", "the", "subject", "is", "sharing", "a", "household", "with", "a", "subject", "randomized", "to", "any", "investigational", "trial", "of", "ondansetron" ]
null
NCT02311361
64:82:treatment
Patients must have disease that is not amenable to potentially curative resection
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "hydroxyurea" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Patients", "must", "have", "disease", "that", "is", "not", "amenable", "to", "potentially", "curative", "resection" ]
null
NCT01419561
1:11:chronic_disease
Neuropathy with or without pain
{ "allergy_name": null, "cancer": null, "chronic_disease": "human immunodeficiency virus (HIV)", "treatment": null }
[ 0, 0, 0, 0, 0 ]
[ "Neuropathy", "with", "or", "without", "pain" ]
null
NCT02553642
,59:74:treatment,
Must have no evidence of progression for at least 4 weeks after treatment is complete and within 28 days prior to first dose of study drug administration
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "gastrostomy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Must", "have", "no", "evidence", "of", "progression", "for", "at", "least", "4", "weeks", "after", "treatment", "is", "complete", "and", "within", "28", "days", "prior", "to", "first", "dose", "of", "study", "drug", "administration" ]
null
NCT02483910
4:27:treatment
On psychotropic medication, but regimen is not stable (Once stabilized, eligibility could be reconsidered.)
{ "allergy_name": null, "cancer": null, "chronic_disease": "dementia", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "On", "psychotropic", "medication,", "but", "regimen", "is", "not", "stable", "(Once", "stabilized,", "eligibility", "could", "be", "reconsidered.)" ]
null
NCT02245841
1:22:treatment
mycophenolate mofetil
{ "allergy_name": null, "cancer": null, "chronic_disease": "pulmonary capillary hemangiomatosis", "treatment": null }
[ 0, 0 ]
[ "mycophenolate", "mofetil" ]
null
NCT02765633
26:58:treatment,,
Participation in another investigational therapeutic drug or investigational therapeutic device trial within 30 days of starting study
{ "allergy_name": null, "cancer": null, "chronic_disease": "obstructive sleep apnea (OSA)", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
[ "Participation", "in", "another", "investigational", "therapeutic", "drug", "or", "investigational", "therapeutic", "device", "trial", "within", "30", "days", "of", "starting", "study" ]
null
NCT03123731
1:7:chronic_disease
stroke
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
[ 2 ]
[ "stroke" ]
null
NCT02080221
1:11:cancer
Metastatic advanced disease
{ "allergy_name": null, "cancer": null, "chronic_disease": "glaucoma", "treatment": null }
[ 0, 0, 0 ]
[ "Metastatic", "advanced", "disease" ]
null
NCT02494869
1:36:chronic_disease,109:118:chronic_disease,120:133:chronic_disease,135:149:chronic_disease
Acute non-cardiopulmonary disorders that may affect exercise performance or be aggravated by exercise (i.e. infection, renal failure, thyrotoxicosis)
{ "allergy_name": null, "cancer": null, "chronic_disease": "Psychiatric or cognitive disorder", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Acute", "non-cardiopulmonary", "disorders", "that", "may", "affect", "exercise", "performance", "or", "be", "aggravated", "by", "exercise", "(i.e.", "infection,", "renal", "failure,", "thyrotoxicosis)" ]
null
NCT02472834
13:19:chronic_disease
Presence of asthma
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "medication" }
[ 0, 0, 2 ]
[ "Presence", "of", "asthma" ]
null
NCT02213289
17:37:chronic_disease
No uncontrolled intercurrent illness or infection
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "treatment" }
[ 0, 0, 0, 2, 0, 2 ]
[ "No", "uncontrolled", "intercurrent", "illness", "or", "infection" ]
null
NCT02584309
1:23:chronic_disease,,
Systolic heart failure defined as left ventricular ejection fraction ≤ 45%
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "hyperbaric chamber" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Systolic", "heart", "failure", "defined", "as", "left", "ventricular", "ejection", "fraction", "≤", "45%" ]
null
NCT02404155
1:16:chronic_disease
viral infection
{ "allergy_name": null, "cancer": null, "chronic_disease": "viral infection", "treatment": null }
[ 0, 2 ]
[ "viral", "infection" ]
3,311
NCT02374333
18:41:chronic_disease
Any uncontrolled active medical disorder that would preclude participation as outlined
{ "allergy_name": null, "cancer": null, "chronic_disease": "aortic or mitral atresia", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Any", "uncontrolled", "active", "medical", "disorder", "that", "would", "preclude", "participation", "as", "outlined" ]
null
NCT02770547
1:22:chronic_disease,,,
Uncontrolled Diabetes (HbA1C > 8.5 measured within 3 months prior to date of consent)
{ "allergy_name": null, "cancer": null, "chronic_disease": "Uncontrolled Diabetes", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Uncontrolled", "Diabetes", "(HbA1C", ">", "8.5", "measured", "within", "3", "months", "prior", "to", "date", "of", "consent)" ]
3,146
NCT02824276
13:21:chronic_disease,23:31:chronic_disease,33:42:chronic_disease,53:73:chronic_disease
evidence of delirium, dementia, psychosis, or other cognitive impairment preventing completion of study procedures
{ "allergy_name": null, "cancer": null, "chronic_disease": "Immunoglobulin A (IgA) deficiency", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "evidence", "of", "delirium,", "dementia,", "psychosis,", "or", "other", "cognitive", "impairment", "preventing", "completion", "of", "study", "procedures" ]
null
NCT02272998
19:39:chronic_disease
Have uncontrolled hypertriglyceridemia
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "vasectomy" }
[ 0, 0, 0 ]
[ "Have", "uncontrolled", "hypertriglyceridemia" ]
null
NCT00147056
8:15:treatment,,,91:106:treatment,,127:136:treatment
Use of Avastin in the preceding two weeks or planned use in the forthcoming two weeks and VEGF inhibitors within + 30 days of treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "external beam radiation" }
[ 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Use", "of", "Avastin", "in", "the", "preceding", "two", "weeks", "or", "planned", "use", "in", "the", "forthcoming", "two", "weeks", "and", "VEGF", "inhibitors", "within", "+", "30", "days", "of", "treatment" ]
null
NCT02234934
9:22:treatment,,
Resting O2 saturation by pulse oximetry < 90% on room air
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "IV anticoagulant therapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Resting", "O2", "saturation", "by", "pulse", "oximetry", "<", "90%", "on", "room", "air" ]
null
NCT02923011
33:72:allergy_name
Known intolerance or allergy to MR contrast agent (gadolinium chelates)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "fMRI" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Known", "intolerance", "or", "allergy", "to", "MR", "contrast", "agent", "(gadolinium", "chelates)" ]
null
NCT02244814
1:13:chronic_disease,15:28:chronic_disease,30:44:chronic_disease,46:67:chronic_disease,69:81:chronic_disease,83:90:treatment,107:119:chronic_disease,121:139:chronic_disease,144:175:chronic_disease
hypertension, renal disease, thrombophilias, rheumatologic disease, preeclampsia, steroid use, history of pancreatitis, infectious disease, or intrauterine growth restriction
{ "allergy_name": null, "cancer": null, "chronic_disease": "anemia", "treatment": "thiazolidinediones (TZD)" }
[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "hypertension,", "renal", "disease,", "thrombophilias,", "rheumatologic", "disease,", "preeclampsia,", "steroid", "use,", "history", "of", "pancreatitis,", "infectious", "disease,", "or", "intrauterine", "growth", "restriction" ]
null
NCT02681614
90:106:chronic_disease,108:144:chronic_disease,146:170:chronic_disease,172:190:chronic_disease,195:232:chronic_disease
Patients with uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
{ "allergy_name": null, "cancer": null, "chronic_disease": "infantile or juvenile gangliosidosis disease", "treatment": null }
[ 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 2, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Patients", "with", "uncontrolled", "intercurrent", "illness", "including,", "but", "not", "limited", "to", "ongoing", "or", "active", "infection,", "symptomatic", "congestive", "heart", "failure,", "unstable", "angina", "pectoris,", "cardiac", "arrhythmia,", "or", "psychiatric", "illness/social", "situations", "that", "would", "limit", "compliance", "with", "study", "requirements" ]
null
NCT02473250
1:14:chronic_disease
hypersplenism
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "pazopanib" }
[ 0 ]
[ "hypersplenism" ]
null
NCT01990209
15:46:cancer
Patients with metastases limited to the bones
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Topical treatment with corticosteroids or other immunosuppressive agents" }
[ 0, 0, 3, 0, 0, 0, 0 ]
[ "Patients", "with", "metastases", "limited", "to", "the", "bones" ]
null
NCT02101853
45:74:chronic_disease,76:89:chronic_disease,91:105:chronic_disease,107:128:chronic_disease,130:144:chronic_disease,146:163:chronic_disease,165:183:chronic_disease,203:231:chronic_disease
Patients known to have one of the following concomitant genetic syndromes: Down syndrome, Bloom syndrome, ataxia-telangiectasia, Fanconi anemia, Kostmann syndrome, Shwachman syndrome or any other known bone marrow failure syndrome
{ "allergy_name": null, "cancer": null, "chronic_disease": "disorientation", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Patients", "known", "to", "have", "one", "of", "the", "following", "concomitant", "genetic", "syndromes:", "Down", "syndrome,", "Bloom", "syndrome,", "ataxia-telangiectasia,", "Fanconi", "anemia,", "Kostmann", "syndrome,", "Shwachman", "syndrome", "or", "any", "other", "known", "bone", "marrow", "failure", "syndrome" ]
null
NCT03045341
1:22:chronic_disease
Binge eating disorder (full criteria as described in the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, 5th edition)
{ "allergy_name": null, "cancer": "Solid Tumors", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Binge", "eating", "disorder", "(full", "criteria", "as", "described", "in", "the", "American", "Psychiatric", "Association", "Diagnostic", "and", "Statistical", "Manual", "of", "Mental", "Disorders,", "5th", "edition)" ]
null
NCT02495389
1:19:chronic_disease
Neurologic disease known to affect the lower urinary tract
{ "allergy_name": null, "cancer": "adenocarcinoma of the pancreas", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Neurologic", "disease", "known", "to", "affect", "the", "lower", "urinary", "tract" ]
null
NCT03113825
30:43:chronic_disease,
Hx of coronary events and/or heart failure within 1 year
{ "allergy_name": null, "cancer": "malignancy", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Hx", "of", "coronary", "events", "and/or", "heart", "failure", "within", "1", "year" ]
null
NCT02638935
,12:27:treatment
Women with breast implants on the same side as the lesion
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "breast implants" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3 ]
[ "Women", "with", "breast", "implants", "on", "the", "same", "side", "as", "the", "lesion" ]
4,052
NCT02570321
42:62:chronic_disease
Participants who are decisionally and/or cognitively impaired
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychosis", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0 ]
[ "Participants", "who", "are", "decisionally", "and/or", "cognitively", "impaired" ]
null
NCT02478255
30:41:treatment,
Patient scheduled to undergo thoracic RT at Duke University to a dose of at least 20 Gy
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Patient", "scheduled", "to", "undergo", "thoracic", "RT", "at", "Duke", "University", "to", "a", "dose", "of", "at", "least", "20", "Gy" ]
null
NCT02459769
1:7:cancer
cancer survivors
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 3, 0 ]
[ "cancer", "survivors" ]
null
NCT02101736
1:27:chronic_disease,39:57:chronic_disease,62:77:chronic_disease,80:94:chronic_disease,96:109:chronic_disease,123:134:chronic_disease,138:150:chronic_disease
inflammatory bowel disease (including ulcerative colitis and Crohn's disease), diverticulitis, cholecystitis, symptomatic cholangitis or appendicitis
{ "allergy_name": null, "cancer": null, "chronic_disease": "generalized anxiety disorder (GAD)", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "inflammatory", "bowel", "disease", "(including", "ulcerative", "colitis", "and", "Crohn's", "disease),", "diverticulitis,", "cholecystitis,", "symptomatic", "cholangitis", "or", "appendicitis" ]
null
NCT02253316
51:67:cancer
Histologically confirmed diagnosis of symptomatic multiple myeloma
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
[ 0, 0, 0, 0, 0, 0, 3 ]
[ "Histologically", "confirmed", "diagnosis", "of", "symptomatic", "multiple", "myeloma" ]
null
NCT02796209
1:35:chronic_disease
Neurogenic Orthostatic Hypotension
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Systemic corticosteroids" }
[ 0, 0, 0 ]
[ "Neurogenic", "Orthostatic", "Hypotension" ]
null
NCT02413970
54:58:treatment
Subjects who have been prescribed, but refuse to try CPAP would be considered intolerant
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychotic", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0 ]
[ "Subjects", "who", "have", "been", "prescribed,", "but", "refuse", "to", "try", "CPAP", "would", "be", "considered", "intolerant" ]
null
NCT02460900
15:26:treatment,
Recent use of Varenicline (by participant report in the past 3 months)
{ "allergy_name": null, "cancer": null, "chronic_disease": "hypercalcemia", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Recent", "use", "of", "Varenicline", "(by", "participant", "report", "in", "the", "past", "3", "months)" ]
null
NCT03020927
31:55:chronic_disease
have a community diagnosis of Autism Spectrum Disorder (as reported by parent)
{ "allergy_name": null, "cancer": null, "chronic_disease": "renal failure", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "have", "a", "community", "diagnosis", "of", "Autism", "Spectrum", "Disorder", "(as", "reported", "by", "parent)" ]
null
NCT02163317
7:16:chronic_disease,20:36:chronic_disease,47:70:treatment
Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
{ "allergy_name": "midodrine hydrochloride", "cancer": null, "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 2, 0, 0, 1, 0, 0, 0, 0, 0 ]
[ "Acute", "bacterial", "or", "fungal", "infection", "requiring", "intravenous", "antibiotics", "at", "the", "time", "of", "registration" ]
null
NCT02124772
35:63:chronic_disease
History of or current evidence of retinal vein occlusion (RVO)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "study drug(s)" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "History", "of", "or", "current", "evidence", "of", "retinal", "vein", "occlusion", "(RVO)" ]
null
NCT02047474
23:35:treatment,,54:66:cancer,78:95:cancer
Patients who received chemotherapy > 5 years ago for malignancies other than pancreatic cancer are eligible
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychiatric disorder", "treatment": "HRCT scan" }
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 0, 0, 0, 3, 0, 0 ]
[ "Patients", "who", "received", "chemotherapy", ">", "5", "years", "ago", "for", "malignancies", "other", "than", "pancreatic", "cancer", "are", "eligible" ]
null
NCT03009981
58:72:treatment,,97:107:treatment,108:120:treatment
Any chronic medical condition requiring a higher dose of corticosteroid than equivalent of 5 mg prednisone/prednisolone once daily
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "pulmonary rehabilitation program" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Any", "chronic", "medical", "condition", "requiring", "a", "higher", "dose", "of", "corticosteroid", "than", "equivalent", "of", "5", "mg", "prednisone/prednisolone", "once", "daily" ]
null
NCT02514083
,,89:98:chronic_disease
Fevers of greater than 100.5 F for greater than or equal to 2 weeks without evidence of infection
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior therapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Fevers", "of", "greater", "than", "100.5", "F", "for", "greater", "than", "or", "equal", "to", "2", "weeks", "without", "evidence", "of", "infection" ]
null
NCT02509507
9:12:cancer,56:79:chronic_disease,83:116:chronic_disease
For non-HCC, there must not be acute or chronic active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "TI chemotherapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 2, 2, 0, 0, 2 ]
[ "For", "non-HCC,", "there", "must", "not", "be", "acute", "or", "chronic", "active", "hepatitis", "B", "virus", "(HBV)", "or", "hepatitis", "C", "virus", "(HCV)", "infection" ]
null
NCT02497300
1:25:chronic_disease,,
Diabetes mellitus type 2 with glycosylated hemoglobin ≥ 6.5%
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "red blood cell transfusions" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Diabetes", "mellitus", "type", "2", "with", "glycosylated", "hemoglobin", "≥", "6.5%" ]
null
NCT02385110
33:61:chronic_disease
A documentation of diagnosis of hemophagocytic lymphocytosis, either newly diagnosed or relapsed/refractory by the treating physician and the PI in the patients chart
{ "allergy_name": null, "cancer": null, "chronic_disease": "TR", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "A", "documentation", "of", "diagnosis", "of", "hemophagocytic", "lymphocytosis,", "either", "newly", "diagnosed", "or", "relapsed/refractory", "by", "the", "treating", "physician", "and", "the", "PI", "in", "the", "patients", "chart" ]
null
NCT02803359
29:65:treatment
Healthy Subjects undergoing thyroid or other open neck surgeries
{ "allergy_name": null, "cancer": "non-melanomatous carcinoma of the skin", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 2, 0, 0, 0, 0, 1 ]
[ "Healthy", "Subjects", "undergoing", "thyroid", "or", "other", "open", "neck", "surgeries" ]
null
NCT01871766
12:21:cancer,23:31:cancer,33:45:cancer,47:55:cancer,57:73:cancer,78:92:cancer,98:116:cancer
High-risk: Embryonal, botryoid, spindle cell, alveolar, undifferentiated, or anaplastic RMS with metastatic disease at diagnosis (stage 4)
{ "allergy_name": null, "cancer": null, "chronic_disease": "hypertension", "treatment": "medication" }
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[ "High-risk:", "Embryonal,", "botryoid,", "spindle", "cell,", "alveolar,", "undifferentiated,", "or", "anaplastic", "RMS", "with", "metastatic", "disease", "at", "diagnosis", "(stage", "4)" ]
null
NCT01570998
1:14:cancer
Node positive patients
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "Prior administration of other intratumoral immunotherapeutics" }
[ 0, 0, 0 ]
[ "Node", "positive", "patients" ]
null
NCT03029442
22:28:cancer
Current diagnosis of cancer or history of cancer
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 0, 0, 0, 3, 0, 0, 0, 3 ]
[ "Current", "diagnosis", "of", "cancer", "or", "history", "of", "cancer" ]
null
NCT02547818
24:35:treatment,
Stability of permitted medications for 4 weeks prior to study start
{ "allergy_name": null, "cancer": "metastatic", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
[ "Stability", "of", "permitted", "medications", "for", "4", "weeks", "prior", "to", "study", "start" ]
null
NCT02620579
21:44:treatment
previous history of upper-extremity surgery
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "brain surgery" }
[ 0, 0, 0, 0, 1 ]
[ "previous", "history", "of", "upper-extremity", "surgery" ]
null
NCT02360579
21:53:treatment
Patients who are on chronic systemic steroid therapy for any reason
{ "allergy_name": null, "cancer": null, "chronic_disease": "severe congestive heart failure NYHA II-IV", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0 ]
[ "Patients", "who", "are", "on", "chronic", "systemic", "steroid", "therapy", "for", "any", "reason" ]
null
NCT03045341
18:45:treatment
Currently taking anti-depressant medications
{ "allergy_name": null, "cancer": null, "chronic_disease": "scoliosis", "treatment": null }
[ 0, 0, 0, 1 ]
[ "Currently", "taking", "anti-depressant", "medications" ]
null
NCT01660607
15:36:treatment
Candidate for autologous transplant
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
[ 0, 0, 0, 1 ]
[ "Candidate", "for", "autologous", "transplant" ]
null
NCT01878617
,,,,214:233:cancer
Age greater than or equal to 3 years and less than 22 years of age at the time of diagnosis (may enroll on Strata W, S or N), OR (2) age is greater than or equal to 22 years and less than 40 years AND patient has SHH medulloblastoma (must enroll on Stratum S)
{ "allergy_name": null, "cancer": "carcinomatous meningitis", "chronic_disease": null, "treatment": null }
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null
NCT02162420
17:49:chronic_disease
With or without clonal cytogenetic abnormalities
{ "allergy_name": null, "cancer": null, "chronic_disease": "mesial temporal lobe sclerosis", "treatment": null }
[ 0, 0, 0, 0, 0, 0 ]
[ "With", "or", "without", "clonal", "cytogenetic", "abnormalities" ]
null
NCT01822522
15:45:treatment,49:68:treatment,70:79:treatment,81:90:treatment,92:111:treatment,113:123:treatment,125:135:treatment,179:189:treatment,239:273:treatment,325:342:treatment
use of any of anti-retrovirals (delavirdine) or protease inhibitors (ritonavir, indinavir, lopinavir/ritonavir, saquinavir, nelfinavir) is permitted; specifically, ritonavir and cobicistat is permitted for participants considered for the CYP3A4-inhibitor based ART regimen arm (Stratum A) of the trial; because the lists of CYP3A4 inhibitors are constantly changing, it is important to regularly consult a frequently-updated list; medical reference texts such as the physicians' desk reference may also provide this information; as part of the enrollment/informed consent procedures
{ "allergy_name": null, "cancer": "brain metastases", "chronic_disease": null, "treatment": "study treatment" }
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null
NCT03061201
1:20:chronic_disease,,
Severe hemophilia A (past evidence of circulating FVIII activity of < 1% normal)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "monoclonal antibodies" }
[ 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Severe", "hemophilia", "A", "(past", "evidence", "of", "circulating", "FVIII", "activity", "of", "<", "1%", "normal)" ]
null
NCT02446236
49:58:chronic_disease
Patients may be eligible upon resolution of the infection
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior therapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Patients", "may", "be", "eligible", "upon", "resolution", "of", "the", "infection" ]
null
NCT02469857
16:35:chronic_disease
a patient with respiratory failure such that an SaO2 of 80% cannot be achieved
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychotic disorders", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "a", "patient", "with", "respiratory", "failure", "such", "that", "an", "SaO2", "of", "80%", "cannot", "be", "achieved" ]
null
NCT02516670
1:22:chronic_disease,24:34:treatment,36:46:treatment
Gastrointestinal (GI): cimetidine, aprepitant
{ "allergy_name": null, "cancer": null, "chronic_disease": "lone symptomatic AF", "treatment": null }
[ 0, 0, 0, 0 ]
[ "Gastrointestinal", "(GI):", "cimetidine,", "aprepitant" ]
null
NCT01754857
,62:74:treatment
lactating females must agree not to breast-feed while taking lenalidomide
{ "allergy_name": null, "cancer": null, "chronic_disease": "congestive heart failure", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "lactating", "females", "must", "agree", "not", "to", "breast-feed", "while", "taking", "lenalidomide" ]
null
NCT02186418
25:34:cancer
Patients with an active malignant disease
{ "allergy_name": null, "cancer": "", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0 ]
[ "Patients", "with", "an", "active", "malignant", "disease" ]
null
NCT02262806
15:26:treatment
Withdrawal of metreleptin led to marked worsening of metabolic parameters
{ "allergy_name": null, "cancer": null, "chronic_disease": "neuropathy", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 2, 0 ]
[ "Withdrawal", "of", "metreleptin", "led", "to", "marked", "worsening", "of", "metabolic", "parameters" ]
null
NCT02410954
8:19:treatment,
Use of medications known to affect Central Nervous System (CNS) function within 5 half-lives screening
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "chemotherapy" }
[ 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Use", "of", "medications", "known", "to", "affect", "Central", "Nervous", "System", "(CNS)", "function", "within", "5", "half-lives", "screening" ]
null
NCT02204098
,28:31:treatment,
no menses for <1 year with FSH and estradiol levels in postmenopausal range, according to institutional standards
{ "allergy_name": null, "cancer": null, "chronic_disease": "suicide attempt", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "no", "menses", "for", "<1", "year", "with", "FSH", "and", "estradiol", "levels", "in", "postmenopausal", "range,", "according", "to", "institutional", "standards" ]
null
NCT01742338
36:43:chronic_disease,45:61:chronic_disease,65:70:chronic_disease
Alternative diagnosis for cause of dyspnea, increased sputum or cough
{ "allergy_name": null, "cancer": null, "chronic_disease": "lethal infections", "treatment": "marrow-suppressive therapy" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 2 ]
[ "Alternative", "diagnosis", "for", "cause", "of", "dyspnea,", "increased", "sputum", "or", "cough" ]
null
NCT02724540
,44:62:treatment,64:68:treatment,70:78:treatment,82:89:treatment,119:148:treatment
Patients must be at least one month beyond prior chemotherapy, PRRT, ablation or surgery, and have recovered from all therapy-associated toxicities
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "(CT)" }
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[ "Patients", "must", "be", "at", "least", "one", "month", "beyond", "prior", "chemotherapy,", "PRRT,", "ablation", "or", "surgery,", "and", "have", "recovered", "from", "all", "therapy-associated", "toxicities" ]
null
NCT02837497
14:36:treatment
AND Received CPR in the ICU setting
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychological impairment", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0 ]
[ "AND", "Received", "CPR", "in", "the", "ICU", "setting" ]
null
NCT00862433
77:102:chronic_disease,,,133:155:chronic_disease,157:181:chronic_disease,183:210:chronic_disease,215:236:chronic_disease
with no known target organ damage (End organ damage includes the following: proliferative retinopathy, serum creatinine < 1.8 m/dl, ischemic heart disease, congestive heart failure, peripheral vascular disease and peripheral neuropathy)
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "low molecular weight heparin (LMWH)" }
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null
NCT02353728
8:35:treatment
Use of ventricular-paced pacemaker
{ "allergy_name": null, "cancer": null, "chronic_disease": "pulmonary", "treatment": null }
[ 0, 0, 0, 4 ]
[ "Use", "of", "ventricular-paced", "pacemaker" ]
null
NCT00044304
1:23:chronic_disease
dysplastic eosinophils on peripheral smear
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "adjuvant endocrine therapy" }
[ 0, 0, 0, 0, 0 ]
[ "dysplastic", "eosinophils", "on", "peripheral", "smear" ]
null
NCT02890485
12:24:treatment
History of knee surgery
{ "allergy_name": null, "cancer": null, "chronic_disease": "neurological disease", "treatment": null }
[ 0, 0, 0, 1 ]
[ "History", "of", "knee", "surgery" ]
null
NCT02549937
1:16:treatment,20:40:treatment,,81:96:treatment,,110:124:treatment
Strong inducers or inhibitors of CYP3A4 within 2 weeks before the first dose of study treatment (3 weeks for St John‟s Wort)
{ "allergy_name": null, "cancer": "invasive ductal carcinoma", "chronic_disease": null, "treatment": null }
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null
NCT02421276
16:71:chronic_disease,,,
Diagnosed with idiopathic or secondary pulmonary arterial hypertension as defined by a mean pulmonary artery pressure > 25 mmHg at rest or > 30 mmHg with exercise
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "ICDs" }
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[ "Diagnosed", "with", "idiopathic", "or", "secondary", "pulmonary", "arterial", "hypertension", "as", "defined", "by", "a", "mean", "pulmonary", "artery", "pressure", ">", "25", "mmHg", "at", "rest", "or", ">", "30", "mmHg", "with", "exercise" ]
null
NCT02025465
1:7:chronic_disease
Asthma
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "treatment" }
[ 0 ]
[ "Asthma" ]
null
NCT02417415
13:20:chronic_disease,22:27:chronic_disease,31:46:chronic_disease
Significant cardiac, renal or hepatic illness
{ "allergy_name": "dacarbazine (DTIC)", "cancer": null, "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 2 ]
[ "Significant", "cardiac,", "renal", "or", "hepatic", "illness" ]
null
NCT02807272
14:18:cancer
Diagnosis of CMML as defined by the World Health Organization (WHO) criteria
{ "allergy_name": null, "cancer": null, "chronic_disease": "Impaired renal function", "treatment": null }
[ 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Diagnosis", "of", "CMML", "as", "defined", "by", "the", "World", "Health", "Organization", "(WHO)", "criteria" ]
null
NCT02323191
23:35:treatment,37:49:treatment,61:82:treatment,94:107:treatment,
Prior toxicities from chemotherapy, radiotherapy, and other anti-cancer therapies, including immunotherapy that have not regressed to Grade <=1 severity (Common Terminology Criteria for Adverse Events [CTCAE] v4.03, or later versions)
{ "allergy_name": null, "cancer": null, "chronic_disease": "Crohn's disease", "treatment": "ustekinumab" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Prior", "toxicities", "from", "chemotherapy,", "radiotherapy,", "and", "other", "anti-cancer", "therapies,", "including", "immunotherapy", "that", "have", "not", "regressed", "to", "Grade", "<=1", "severity", "(Common", "Terminology", "Criteria", "for", "Adverse", "Events", "[CTCAE]", "v4.03,", "or", "later", "versions)" ]
null
NCT02479230
,,,83:98:cancer
Alkaline phosphatase < 2.5 upper limit of normal (ULN) (< 10 x ULN in presence of bone metastases)
{ "allergy_name": null, "cancer": "Tumor", "chronic_disease": null, "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Alkaline", "phosphatase", "<", "2.5", "upper", "limit", "of", "normal", "(ULN)", "(<", "10", "x", "ULN", "in", "presence", "of", "bone", "metastases)" ]
null
NCT02533674
27:38:allergy_name
Known hypersensitivity to gemcitabine or any component of the formulation
{ "allergy_name": null, "cancer": null, "chronic_disease": "hepatitis B", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Known", "hypersensitivity", "to", "gemcitabine", "or", "any", "component", "of", "the", "formulation" ]
null
NCT02004275
14:25:chronic_disease
Known active hepatitis C based on
{ "allergy_name": null, "cancer": null, "chronic_disease": "human immunodeficiency virus (HIV)", "treatment": null }
[ 0, 0, 2, 2, 0, 0 ]
[ "Known", "active", "hepatitis", "C", "based", "on" ]
null
NCT02498301
,94:105:treatment
Subject is currently taking or plans to take during deployment at least one of the following medications
{ "allergy_name": null, "cancer": "primary or metastatic brain tumor", "chronic_disease": null, "treatment": "tumor resection" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Subject", "is", "currently", "taking", "or", "plans", "to", "take", "during", "deployment", "at", "least", "one", "of", "the", "following", "medications" ]
null
NCT01045148
1:16:treatment,21:46:cancer,48:70:treatment,72:93:treatment
Radical surgery for carcinoma of the prostate, prior pelvic radiation, pelvic surgical clips or other metallic foreign bodies
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "low molecular-weight heparin" }
[ 0, 1, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "Radical", "surgery", "for", "carcinoma", "of", "the", "prostate,", "prior", "pelvic", "radiation,", "pelvic", "surgical", "clips", "or", "other", "metallic", "foreign", "bodies" ]
null
NCT01130077
42:64:treatment
Patients in Stratum F must have received craniospinal radiation
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "caffeine" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Patients", "in", "Stratum", "F", "must", "have", "received", "craniospinal", "radiation" ]
null
NCT02315196
1:20:treatment,56:62:treatment,,149:167:cancer
Computed tomography of the chest, abdomen, and pelvis (CT CAP) and bone scan performed within 30 days prior to study entry and does not demonstrate metastatic disease
{ "allergy_name": null, "cancer": "malignant tumor", "chronic_disease": null, "treatment": "conventional radiotherapy" }
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[ "Computed", "tomography", "of", "the", "chest,", "abdomen,", "and", "pelvis", "(CT", "CAP)", "and", "bone", "scan", "performed", "within", "30", "days", "prior", "to", "study", "entry", "and", "does", "not", "demonstrate", "metastatic", "disease" ]
null
NCT02460835
,,122:128:cancer,,
Zubrod performance status of less than or equal to 2 (Zubrod performance status is a measure that attempts to quantify a cancer patients' general well-being. Scores run from 0 to 5 where 0 denotes normal activity and 5 denotes death)
{ "allergy_name": null, "cancer": null, "chronic_disease": "HIV", "treatment": null }
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[ "Zubrod", "performance", "status", "of", "less", "than", "or", "equal", "to", "2", "(Zubrod", "performance", "status", "is", "a", "measure", "that", "attempts", "to", "quantify", "a", "cancer", "patients'", "general", "well-being.", "Scores", "run", "from", "0", "to", "5", "where", "0", "denotes", "normal", "activity", "and", "5", "denotes", "death)" ]
null
NCT02688647
51:54:chronic_disease,51:64:chronic_disease,,129:136:treatment
Documented sustained improvement of the subject's IPF condition up to 12 months before study entry with or without IPF-specific therapy
{ "allergy_name": null, "cancer": null, "chronic_disease": "suicidal ideation, behavior and attempts", "treatment": null }
[ 0, 0, 0, 0, 0, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1 ]
[ "Documented", "sustained", "improvement", "of", "the", "subject's", "IPF", "condition", "up", "to", "12", "months", "before", "study", "entry", "with", "or", "without", "IPF-specific", "therapy" ]
null
NCT03161028
1:27:chronic_disease,19:27:chronic_disease,58:83:treatment
Insulin-dependent diabetes or diabetes not controlled on oral diabetes medications
{ "allergy_name": null, "cancer": "CNS intracranial tumor", "chronic_disease": null, "treatment": null }
[ 0, 2, 0, 2, 0, 0, 0, 0, 2, 1 ]
[ "Insulin-dependent", "diabetes", "or", "diabetes", "not", "controlled", "on", "oral", "diabetes", "medications" ]
null
NCT02516696
16:52:treatment,,91:106:treatment,118:133:treatment,,194:207:treatment
Subject has no prior anti-myeloma treatment therapy within 14 days prior to initiation of study treatment except for corticosteroids with a maximum allowed dosage equivalent to three pulses of dexamethasone (40mg daily for 4 days equals one pulse)
{ "allergy_name": null, "cancer": null, "chronic_disease": "Lumbar Anterior Fusion", "treatment": null }
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[ "Subject", "has", "no", "prior", "anti-myeloma", "treatment", "therapy", "within", "14", "days", "prior", "to", "initiation", "of", "study", "treatment", "except", "for", "corticosteroids", "with", "a", "maximum", "allowed", "dosage", "equivalent", "to", "three", "pulses", "of", "dexamethasone", "(40mg", "daily", "for", "4", "days", "equals", "one", "pulse)" ]
null
NCT02672098
21:36:chronic_disease
Patients with known acute hepatitis
{ "allergy_name": null, "cancer": null, "chronic_disease": "Iron-deficiency anemia", "treatment": null }
[ 0, 0, 0, 0, 2 ]
[ "Patients", "with", "known", "acute", "hepatitis" ]
null
NCT02187198
44:55:chronic_disease,65:76:chronic_disease,84:98:chronic_disease,100:105:chronic_disease,107:116:chronic_disease,121:138:chronic_disease,149:172:treatment
serious unstable medical illness including bradycardia or other arrhythmias, major cardiovascular, renal, endocrine, or hepatic disorders for which buprenorphine treatment is contraindicated or which at the determination of the MD is medically dangerous
{ "allergy_name": null, "cancer": null, "chronic_disease": "psychiatric", "treatment": "weight-affecting medications" }
[ 0, 0, 0, 2, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "serious", "unstable", "medical", "illness", "including", "bradycardia", "or", "other", "arrhythmias,", "major", "cardiovascular,", "renal,", "endocrine,", "or", "hepatic", "disorders", "for", "which", "buprenorphine", "treatment", "is", "contraindicated", "or", "which", "at", "the", "determination", "of", "the", "MD", "is", "medically", "dangerous" ]
null
NCT02509507
16:30:treatment,113:123:cancer,128:148:treatment
expected other cancer therapy while on study with the exception of local radiation to the site of bone or other metastasis for palliative treatment
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "prior gene transfer therapy" }
[ 0, 0, 3, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1 ]
[ "expected", "other", "cancer", "therapy", "while", "on", "study", "with", "the", "exception", "of", "local", "radiation", "to", "the", "site", "of", "bone", "or", "other", "metastasis", "for", "palliative", "treatment" ]
null
NCT02169037
1:23:chronic_disease,50:58:treatment,80:105:chronic_disease,111:132:chronic_disease
acquired heart disease that may increase risk of ablation, such as significant ventricular septal defect post myocardial infarction
{ "allergy_name": null, "cancer": null, "chronic_disease": null, "treatment": "intravenous nitroglycerine" }
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
[ "acquired", "heart", "disease", "that", "may", "increase", "risk", "of", "ablation,", "such", "as", "significant", "ventricular", "septal", "defect", "post", "myocardial", "infarction" ]
null
NCT02982226
1:16:chronic_disease
Fat Pad Atrophy
{ "allergy_name": null, "cancer": null, "chronic_disease": "cardiac diseases", "treatment": null }
[ 0, 0, 0 ]
[ "Fat", "Pad", "Atrophy" ]
null
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