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7.13k
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NCT02446886
|
13:34:chronic_disease,46:50:chronic_disease,54:58:chronic_disease
|
Progressive neurological disorder other than RRMS or SPMS
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Left or right ventricular aneurysm",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Progressive",
"neurological",
"disorder",
"other",
"than",
"RRMS",
"or",
"SPMS"
] | null |
NCT01989507
|
49:69:treatment
|
actively quitting smoking or current use of any nicotine replacement or other smoking cessation treatment
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "cardiopulmonary",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
1,
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"actively",
"quitting",
"smoking",
"or",
"current",
"use",
"of",
"any",
"nicotine",
"replacement",
"or",
"other",
"smoking",
"cessation",
"treatment"
] | null |
NCT02667418
|
1:11:treatment
|
vancomycin
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "constrictive pericarditis",
"treatment": null
}
|
[
0
] |
[
"vancomycin"
] | null |
NCT02354703
|
114:125:treatment
|
As of Screen Visit, the subject is sharing a household with a subject randomized to any investigational trial of ondansetron
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Pulmonary hypertension",
"treatment": null
}
|
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"randomized",
"to",
"any",
"investigational",
"trial",
"of",
"ondansetron"
] | null |
NCT02311361
|
64:82:treatment
|
Patients must have disease that is not amenable to potentially curative resection
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "hydroxyurea"
}
|
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"that",
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"not",
"amenable",
"to",
"potentially",
"curative",
"resection"
] | null |
NCT01419561
|
1:11:chronic_disease
|
Neuropathy with or without pain
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "human immunodeficiency virus (HIV)",
"treatment": null
}
|
[
0,
0,
0,
0,
0
] |
[
"Neuropathy",
"with",
"or",
"without",
"pain"
] | null |
NCT02553642
|
,59:74:treatment,
|
Must have no evidence of progression for at least 4 weeks after treatment is complete and within 28 days prior to first dose of study drug administration
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "gastrostomy"
}
|
[
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"and",
"within",
"28",
"days",
"prior",
"to",
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"of",
"study",
"drug",
"administration"
] | null |
NCT02483910
|
4:27:treatment
|
On psychotropic medication, but regimen is not stable (Once stabilized, eligibility could be reconsidered.)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "dementia",
"treatment": null
}
|
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0,
0,
0,
0,
0,
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0,
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[
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"is",
"not",
"stable",
"(Once",
"stabilized,",
"eligibility",
"could",
"be",
"reconsidered.)"
] | null |
NCT02245841
|
1:22:treatment
|
mycophenolate mofetil
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "pulmonary capillary hemangiomatosis",
"treatment": null
}
|
[
0,
0
] |
[
"mycophenolate",
"mofetil"
] | null |
NCT02765633
|
26:58:treatment,,
|
Participation in another investigational therapeutic drug or investigational therapeutic device trial within 30 days of starting study
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "obstructive sleep apnea (OSA)",
"treatment": null
}
|
[
0,
0,
0,
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0,
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[
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"or",
"investigational",
"therapeutic",
"device",
"trial",
"within",
"30",
"days",
"of",
"starting",
"study"
] | null |
NCT03123731
|
1:7:chronic_disease
|
stroke
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "chemotherapy"
}
|
[
2
] |
[
"stroke"
] | null |
NCT02080221
|
1:11:cancer
|
Metastatic advanced disease
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "glaucoma",
"treatment": null
}
|
[
0,
0,
0
] |
[
"Metastatic",
"advanced",
"disease"
] | null |
NCT02494869
|
1:36:chronic_disease,109:118:chronic_disease,120:133:chronic_disease,135:149:chronic_disease
|
Acute non-cardiopulmonary disorders that may affect exercise performance or be aggravated by exercise (i.e. infection, renal failure, thyrotoxicosis)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Psychiatric or cognitive disorder",
"treatment": null
}
|
[
0,
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[
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"exercise",
"performance",
"or",
"be",
"aggravated",
"by",
"exercise",
"(i.e.",
"infection,",
"renal",
"failure,",
"thyrotoxicosis)"
] | null |
NCT02472834
|
13:19:chronic_disease
|
Presence of asthma
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "medication"
}
|
[
0,
0,
2
] |
[
"Presence",
"of",
"asthma"
] | null |
NCT02213289
|
17:37:chronic_disease
|
No uncontrolled intercurrent illness or infection
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "treatment"
}
|
[
0,
0,
0,
2,
0,
2
] |
[
"No",
"uncontrolled",
"intercurrent",
"illness",
"or",
"infection"
] | null |
NCT02584309
|
1:23:chronic_disease,,
|
Systolic heart failure defined as left ventricular ejection fraction ≤ 45%
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "hyperbaric chamber"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Systolic",
"heart",
"failure",
"defined",
"as",
"left",
"ventricular",
"ejection",
"fraction",
"≤",
"45%"
] | null |
NCT02404155
|
1:16:chronic_disease
|
viral infection
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "viral infection",
"treatment": null
}
|
[
0,
2
] |
[
"viral",
"infection"
] | 3,311
|
NCT02374333
|
18:41:chronic_disease
|
Any uncontrolled active medical disorder that would preclude participation as outlined
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "aortic or mitral atresia",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Any",
"uncontrolled",
"active",
"medical",
"disorder",
"that",
"would",
"preclude",
"participation",
"as",
"outlined"
] | null |
NCT02770547
|
1:22:chronic_disease,,,
|
Uncontrolled Diabetes (HbA1C > 8.5 measured within 3 months prior to date of consent)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Uncontrolled Diabetes",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
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[
"Uncontrolled",
"Diabetes",
"(HbA1C",
">",
"8.5",
"measured",
"within",
"3",
"months",
"prior",
"to",
"date",
"of",
"consent)"
] | 3,146
|
NCT02824276
|
13:21:chronic_disease,23:31:chronic_disease,33:42:chronic_disease,53:73:chronic_disease
|
evidence of delirium, dementia, psychosis, or other cognitive impairment preventing completion of study procedures
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Immunoglobulin A (IgA) deficiency",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"evidence",
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"delirium,",
"dementia,",
"psychosis,",
"or",
"other",
"cognitive",
"impairment",
"preventing",
"completion",
"of",
"study",
"procedures"
] | null |
NCT02272998
|
19:39:chronic_disease
|
Have uncontrolled hypertriglyceridemia
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "vasectomy"
}
|
[
0,
0,
0
] |
[
"Have",
"uncontrolled",
"hypertriglyceridemia"
] | null |
NCT00147056
|
8:15:treatment,,,91:106:treatment,,127:136:treatment
|
Use of Avastin in the preceding two weeks or planned use in the forthcoming two weeks and VEGF inhibitors within + 30 days of treatment
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "external beam radiation"
}
|
[
0,
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[
"Use",
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"in",
"the",
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"two",
"weeks",
"or",
"planned",
"use",
"in",
"the",
"forthcoming",
"two",
"weeks",
"and",
"VEGF",
"inhibitors",
"within",
"+",
"30",
"days",
"of",
"treatment"
] | null |
NCT02234934
|
9:22:treatment,,
|
Resting O2 saturation by pulse oximetry < 90% on room air
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "IV anticoagulant therapy"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Resting",
"O2",
"saturation",
"by",
"pulse",
"oximetry",
"<",
"90%",
"on",
"room",
"air"
] | null |
NCT02923011
|
33:72:allergy_name
|
Known intolerance or allergy to MR contrast agent (gadolinium chelates)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "fMRI"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Known",
"intolerance",
"or",
"allergy",
"to",
"MR",
"contrast",
"agent",
"(gadolinium",
"chelates)"
] | null |
NCT02244814
|
1:13:chronic_disease,15:28:chronic_disease,30:44:chronic_disease,46:67:chronic_disease,69:81:chronic_disease,83:90:treatment,107:119:chronic_disease,121:139:chronic_disease,144:175:chronic_disease
|
hypertension, renal disease, thrombophilias, rheumatologic disease, preeclampsia, steroid use, history of pancreatitis, infectious disease, or intrauterine growth restriction
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "anemia",
"treatment": "thiazolidinediones (TZD)"
}
|
[
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"hypertension,",
"renal",
"disease,",
"thrombophilias,",
"rheumatologic",
"disease,",
"preeclampsia,",
"steroid",
"use,",
"history",
"of",
"pancreatitis,",
"infectious",
"disease,",
"or",
"intrauterine",
"growth",
"restriction"
] | null |
NCT02681614
|
90:106:chronic_disease,108:144:chronic_disease,146:170:chronic_disease,172:190:chronic_disease,195:232:chronic_disease
|
Patients with uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "infantile or juvenile gangliosidosis disease",
"treatment": null
}
|
[
0,
0,
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0
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[
"Patients",
"with",
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"intercurrent",
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"including,",
"but",
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"limited",
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"ongoing",
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"active",
"infection,",
"symptomatic",
"congestive",
"heart",
"failure,",
"unstable",
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"cardiac",
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"or",
"psychiatric",
"illness/social",
"situations",
"that",
"would",
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"compliance",
"with",
"study",
"requirements"
] | null |
NCT02473250
|
1:14:chronic_disease
|
hypersplenism
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "pazopanib"
}
|
[
0
] |
[
"hypersplenism"
] | null |
NCT01990209
|
15:46:cancer
|
Patients with metastases limited to the bones
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "Topical treatment with corticosteroids or other immunosuppressive agents"
}
|
[
0,
0,
3,
0,
0,
0,
0
] |
[
"Patients",
"with",
"metastases",
"limited",
"to",
"the",
"bones"
] | null |
NCT02101853
|
45:74:chronic_disease,76:89:chronic_disease,91:105:chronic_disease,107:128:chronic_disease,130:144:chronic_disease,146:163:chronic_disease,165:183:chronic_disease,203:231:chronic_disease
|
Patients known to have one of the following concomitant genetic syndromes: Down syndrome, Bloom syndrome, ataxia-telangiectasia, Fanconi anemia, Kostmann syndrome, Shwachman syndrome or any other known bone marrow failure syndrome
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "disorientation",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
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0,
0,
0,
2,
0,
0,
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0,
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2
] |
[
"Patients",
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"one",
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"the",
"following",
"concomitant",
"genetic",
"syndromes:",
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"syndrome,",
"Bloom",
"syndrome,",
"ataxia-telangiectasia,",
"Fanconi",
"anemia,",
"Kostmann",
"syndrome,",
"Shwachman",
"syndrome",
"or",
"any",
"other",
"known",
"bone",
"marrow",
"failure",
"syndrome"
] | null |
NCT03045341
|
1:22:chronic_disease
|
Binge eating disorder (full criteria as described in the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, 5th edition)
|
{
"allergy_name": null,
"cancer": "Solid Tumors",
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
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[
"Binge",
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"disorder",
"(full",
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"the",
"American",
"Psychiatric",
"Association",
"Diagnostic",
"and",
"Statistical",
"Manual",
"of",
"Mental",
"Disorders,",
"5th",
"edition)"
] | null |
NCT02495389
|
1:19:chronic_disease
|
Neurologic disease known to affect the lower urinary tract
|
{
"allergy_name": null,
"cancer": "adenocarcinoma of the pancreas",
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Neurologic",
"disease",
"known",
"to",
"affect",
"the",
"lower",
"urinary",
"tract"
] | null |
NCT03113825
|
30:43:chronic_disease,
|
Hx of coronary events and/or heart failure within 1 year
|
{
"allergy_name": null,
"cancer": "malignancy",
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"Hx",
"of",
"coronary",
"events",
"and/or",
"heart",
"failure",
"within",
"1",
"year"
] | null |
NCT02638935
|
,12:27:treatment
|
Women with breast implants on the same side as the lesion
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "breast implants"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3
] |
[
"Women",
"with",
"breast",
"implants",
"on",
"the",
"same",
"side",
"as",
"the",
"lesion"
] | 4,052
|
NCT02570321
|
42:62:chronic_disease
|
Participants who are decisionally and/or cognitively impaired
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychosis",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0
] |
[
"Participants",
"who",
"are",
"decisionally",
"and/or",
"cognitively",
"impaired"
] | null |
NCT02478255
|
30:41:treatment,
|
Patient scheduled to undergo thoracic RT at Duke University to a dose of at least 20 Gy
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "HIV",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
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0,
0,
0
] |
[
"Patient",
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"thoracic",
"RT",
"at",
"Duke",
"University",
"to",
"a",
"dose",
"of",
"at",
"least",
"20",
"Gy"
] | null |
NCT02459769
|
1:7:cancer
|
cancer survivors
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "HIV",
"treatment": null
}
|
[
3,
0
] |
[
"cancer",
"survivors"
] | null |
NCT02101736
|
1:27:chronic_disease,39:57:chronic_disease,62:77:chronic_disease,80:94:chronic_disease,96:109:chronic_disease,123:134:chronic_disease,138:150:chronic_disease
|
inflammatory bowel disease (including ulcerative colitis and Crohn's disease), diverticulitis, cholecystitis, symptomatic cholangitis or appendicitis
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "generalized anxiety disorder (GAD)",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
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[
"inflammatory",
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"diverticulitis,",
"cholecystitis,",
"symptomatic",
"cholangitis",
"or",
"appendicitis"
] | null |
NCT02253316
|
51:67:cancer
|
Histologically confirmed diagnosis of symptomatic multiple myeloma
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "chemotherapy"
}
|
[
0,
0,
0,
0,
0,
0,
3
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[
"Histologically",
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"diagnosis",
"of",
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"multiple",
"myeloma"
] | null |
NCT02796209
|
1:35:chronic_disease
|
Neurogenic Orthostatic Hypotension
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "Systemic corticosteroids"
}
|
[
0,
0,
0
] |
[
"Neurogenic",
"Orthostatic",
"Hypotension"
] | null |
NCT02413970
|
54:58:treatment
|
Subjects who have been prescribed, but refuse to try CPAP would be considered intolerant
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychotic",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
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[
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"CPAP",
"would",
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] | null |
NCT02460900
|
15:26:treatment,
|
Recent use of Varenicline (by participant report in the past 3 months)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "hypercalcemia",
"treatment": null
}
|
[
0,
0,
0,
0,
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[
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] | null |
NCT03020927
|
31:55:chronic_disease
|
have a community diagnosis of Autism Spectrum Disorder (as reported by parent)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "renal failure",
"treatment": null
}
|
[
0,
0,
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0,
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[
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"(as",
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"by",
"parent)"
] | null |
NCT02163317
|
7:16:chronic_disease,20:36:chronic_disease,47:70:treatment
|
Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
|
{
"allergy_name": "midodrine hydrochloride",
"cancer": null,
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
2,
0,
0,
1,
0,
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0
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[
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"infection",
"requiring",
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"antibiotics",
"at",
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"time",
"of",
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] | null |
NCT02124772
|
35:63:chronic_disease
|
History of or current evidence of retinal vein occlusion (RVO)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "study drug(s)"
}
|
[
0,
0,
0,
0,
0,
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0,
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0
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[
"History",
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"retinal",
"vein",
"occlusion",
"(RVO)"
] | null |
NCT02047474
|
23:35:treatment,,54:66:cancer,78:95:cancer
|
Patients who received chemotherapy > 5 years ago for malignancies other than pancreatic cancer are eligible
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychiatric disorder",
"treatment": "HRCT scan"
}
|
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0,
0,
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0,
0,
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0,
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[
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"for",
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"other",
"than",
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"cancer",
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] | null |
NCT03009981
|
58:72:treatment,,97:107:treatment,108:120:treatment
|
Any chronic medical condition requiring a higher dose of corticosteroid than equivalent of 5 mg prednisone/prednisolone once daily
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "pulmonary rehabilitation program"
}
|
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[
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"prednisone/prednisolone",
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] | null |
NCT02514083
|
,,89:98:chronic_disease
|
Fevers of greater than 100.5 F for greater than or equal to 2 weeks without evidence of infection
|
{
"allergy_name": null,
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|
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"evidence",
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] | null |
NCT02509507
|
9:12:cancer,56:79:chronic_disease,83:116:chronic_disease
|
For non-HCC, there must not be acute or chronic active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection
|
{
"allergy_name": null,
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"treatment": "TI chemotherapy"
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"C",
"virus",
"(HCV)",
"infection"
] | null |
NCT02497300
|
1:25:chronic_disease,,
|
Diabetes mellitus type 2 with glycosylated hemoglobin ≥ 6.5%
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "red blood cell transfusions"
}
|
[
0,
0,
0,
0,
0,
0,
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0
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[
"Diabetes",
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"≥",
"6.5%"
] | null |
NCT02385110
|
33:61:chronic_disease
|
A documentation of diagnosis of hemophagocytic lymphocytosis, either newly diagnosed or relapsed/refractory by the treating physician and the PI in the patients chart
|
{
"allergy_name": null,
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"chronic_disease": "TR",
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}
|
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[
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"patients",
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] | null |
NCT02803359
|
29:65:treatment
|
Healthy Subjects undergoing thyroid or other open neck surgeries
|
{
"allergy_name": null,
"cancer": "non-melanomatous carcinoma of the skin",
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
2,
0,
0,
0,
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1
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[
"Healthy",
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"thyroid",
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"other",
"open",
"neck",
"surgeries"
] | null |
NCT01871766
|
12:21:cancer,23:31:cancer,33:45:cancer,47:55:cancer,57:73:cancer,78:92:cancer,98:116:cancer
|
High-risk: Embryonal, botryoid, spindle cell, alveolar, undifferentiated, or anaplastic RMS with metastatic disease at diagnosis (stage 4)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "hypertension",
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[
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] | null |
NCT01570998
|
1:14:cancer
|
Node positive patients
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "Prior administration of other intratumoral immunotherapeutics"
}
|
[
0,
0,
0
] |
[
"Node",
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"patients"
] | null |
NCT03029442
|
22:28:cancer
|
Current diagnosis of cancer or history of cancer
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "HIV",
"treatment": null
}
|
[
0,
0,
0,
3,
0,
0,
0,
3
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[
"Current",
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"cancer"
] | null |
NCT02547818
|
24:35:treatment,
|
Stability of permitted medications for 4 weeks prior to study start
|
{
"allergy_name": null,
"cancer": "metastatic",
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"treatment": null
}
|
[
0,
0,
0,
1,
0,
0,
0,
0,
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0,
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[
"Stability",
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"to",
"study",
"start"
] | null |
NCT02620579
|
21:44:treatment
|
previous history of upper-extremity surgery
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "brain surgery"
}
|
[
0,
0,
0,
0,
1
] |
[
"previous",
"history",
"of",
"upper-extremity",
"surgery"
] | null |
NCT02360579
|
21:53:treatment
|
Patients who are on chronic systemic steroid therapy for any reason
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "severe congestive heart failure NYHA II-IV",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
1,
1,
0,
0,
0
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[
"Patients",
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"steroid",
"therapy",
"for",
"any",
"reason"
] | null |
NCT03045341
|
18:45:treatment
|
Currently taking anti-depressant medications
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "scoliosis",
"treatment": null
}
|
[
0,
0,
0,
1
] |
[
"Currently",
"taking",
"anti-depressant",
"medications"
] | null |
NCT01660607
|
15:36:treatment
|
Candidate for autologous transplant
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "HIV",
"treatment": null
}
|
[
0,
0,
0,
1
] |
[
"Candidate",
"for",
"autologous",
"transplant"
] | null |
NCT01878617
|
,,,,214:233:cancer
|
Age greater than or equal to 3 years and less than 22 years of age at the time of diagnosis (may enroll on Strata W, S or N), OR (2) age is greater than or equal to 22 years and less than 40 years AND patient has SHH medulloblastoma (must enroll on Stratum S)
|
{
"allergy_name": null,
"cancer": "carcinomatous meningitis",
"chronic_disease": null,
"treatment": null
}
|
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] | null |
NCT02162420
|
17:49:chronic_disease
|
With or without clonal cytogenetic abnormalities
|
{
"allergy_name": null,
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"chronic_disease": "mesial temporal lobe sclerosis",
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}
|
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0,
0,
0,
0,
0,
0
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[
"With",
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NCT01822522
|
15:45:treatment,49:68:treatment,70:79:treatment,81:90:treatment,92:111:treatment,113:123:treatment,125:135:treatment,179:189:treatment,239:273:treatment,325:342:treatment
|
use of any of anti-retrovirals (delavirdine) or protease inhibitors (ritonavir, indinavir, lopinavir/ritonavir, saquinavir, nelfinavir) is permitted; specifically, ritonavir and cobicistat is permitted for participants considered for the CYP3A4-inhibitor based ART regimen arm (Stratum A) of the trial; because the lists of CYP3A4 inhibitors are constantly changing, it is important to regularly consult a frequently-updated list; medical reference texts such as the physicians' desk reference may also provide this information; as part of the enrollment/informed consent procedures
|
{
"allergy_name": null,
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] | null |
NCT03061201
|
1:20:chronic_disease,,
|
Severe hemophilia A (past evidence of circulating FVIII activity of < 1% normal)
|
{
"allergy_name": null,
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"chronic_disease": null,
"treatment": "monoclonal antibodies"
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NCT02446236
|
49:58:chronic_disease
|
Patients may be eligible upon resolution of the infection
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "prior therapy"
}
|
[
0,
0,
0,
0,
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[
"Patients",
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] | null |
NCT02469857
|
16:35:chronic_disease
|
a patient with respiratory failure such that an SaO2 of 80% cannot be achieved
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychotic disorders",
"treatment": null
}
|
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"cannot",
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"achieved"
] | null |
NCT02516670
|
1:22:chronic_disease,24:34:treatment,36:46:treatment
|
Gastrointestinal (GI): cimetidine, aprepitant
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "lone symptomatic AF",
"treatment": null
}
|
[
0,
0,
0,
0
] |
[
"Gastrointestinal",
"(GI):",
"cimetidine,",
"aprepitant"
] | null |
NCT01754857
|
,62:74:treatment
|
lactating females must agree not to breast-feed while taking lenalidomide
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "congestive heart failure",
"treatment": null
}
|
[
0,
0,
0,
0,
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[
"lactating",
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"must",
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"not",
"to",
"breast-feed",
"while",
"taking",
"lenalidomide"
] | null |
NCT02186418
|
25:34:cancer
|
Patients with an active malignant disease
|
{
"allergy_name": null,
"cancer": "",
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0
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"malignant",
"disease"
] | null |
NCT02262806
|
15:26:treatment
|
Withdrawal of metreleptin led to marked worsening of metabolic parameters
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "neuropathy",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
2,
0
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[
"Withdrawal",
"of",
"metreleptin",
"led",
"to",
"marked",
"worsening",
"of",
"metabolic",
"parameters"
] | null |
NCT02410954
|
8:19:treatment,
|
Use of medications known to affect Central Nervous System (CNS) function within 5 half-lives screening
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "chemotherapy"
}
|
[
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
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[
"Use",
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"affect",
"Central",
"Nervous",
"System",
"(CNS)",
"function",
"within",
"5",
"half-lives",
"screening"
] | null |
NCT02204098
|
,28:31:treatment,
|
no menses for <1 year with FSH and estradiol levels in postmenopausal range, according to institutional standards
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "suicide attempt",
"treatment": null
}
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0,
0,
0,
0,
0,
0,
0,
0,
0,
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[
"no",
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"according",
"to",
"institutional",
"standards"
] | null |
NCT01742338
|
36:43:chronic_disease,45:61:chronic_disease,65:70:chronic_disease
|
Alternative diagnosis for cause of dyspnea, increased sputum or cough
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "lethal infections",
"treatment": "marrow-suppressive therapy"
}
|
[
0,
0,
0,
0,
0,
0,
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0,
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2
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[
"Alternative",
"diagnosis",
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"dyspnea,",
"increased",
"sputum",
"or",
"cough"
] | null |
NCT02724540
|
,44:62:treatment,64:68:treatment,70:78:treatment,82:89:treatment,119:148:treatment
|
Patients must be at least one month beyond prior chemotherapy, PRRT, ablation or surgery, and have recovered from all therapy-associated toxicities
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "(CT)"
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[
0,
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[
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"and",
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"from",
"all",
"therapy-associated",
"toxicities"
] | null |
NCT02837497
|
14:36:treatment
|
AND Received CPR in the ICU setting
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychological impairment",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0
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[
"AND",
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"CPR",
"in",
"the",
"ICU",
"setting"
] | null |
NCT00862433
|
77:102:chronic_disease,,,133:155:chronic_disease,157:181:chronic_disease,183:210:chronic_disease,215:236:chronic_disease
|
with no known target organ damage (End organ damage includes the following: proliferative retinopathy, serum creatinine < 1.8 m/dl, ischemic heart disease, congestive heart failure, peripheral vascular disease and peripheral neuropathy)
|
{
"allergy_name": null,
"cancer": null,
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"treatment": "low molecular weight heparin (LMWH)"
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[
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"congestive",
"heart",
"failure,",
"peripheral",
"vascular",
"disease",
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"peripheral",
"neuropathy)"
] | null |
NCT02353728
|
8:35:treatment
|
Use of ventricular-paced pacemaker
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "pulmonary",
"treatment": null
}
|
[
0,
0,
0,
4
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[
"Use",
"of",
"ventricular-paced",
"pacemaker"
] | null |
NCT00044304
|
1:23:chronic_disease
|
dysplastic eosinophils on peripheral smear
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "adjuvant endocrine therapy"
}
|
[
0,
0,
0,
0,
0
] |
[
"dysplastic",
"eosinophils",
"on",
"peripheral",
"smear"
] | null |
NCT02890485
|
12:24:treatment
|
History of knee surgery
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "neurological disease",
"treatment": null
}
|
[
0,
0,
0,
1
] |
[
"History",
"of",
"knee",
"surgery"
] | null |
NCT02549937
|
1:16:treatment,20:40:treatment,,81:96:treatment,,110:124:treatment
|
Strong inducers or inhibitors of CYP3A4 within 2 weeks before the first dose of study treatment (3 weeks for St John‟s Wort)
|
{
"allergy_name": null,
"cancer": "invasive ductal carcinoma",
"chronic_disease": null,
"treatment": null
}
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[
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"St",
"John‟s",
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] | null |
NCT02421276
|
16:71:chronic_disease,,,
|
Diagnosed with idiopathic or secondary pulmonary arterial hypertension as defined by a mean pulmonary artery pressure > 25 mmHg at rest or > 30 mmHg with exercise
|
{
"allergy_name": null,
"cancer": null,
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[
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] | null |
NCT02025465
|
1:7:chronic_disease
|
Asthma
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "treatment"
}
|
[
0
] |
[
"Asthma"
] | null |
NCT02417415
|
13:20:chronic_disease,22:27:chronic_disease,31:46:chronic_disease
|
Significant cardiac, renal or hepatic illness
|
{
"allergy_name": "dacarbazine (DTIC)",
"cancer": null,
"chronic_disease": null,
"treatment": null
}
|
[
0,
0,
0,
0,
0,
2
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[
"Significant",
"cardiac,",
"renal",
"or",
"hepatic",
"illness"
] | null |
NCT02807272
|
14:18:cancer
|
Diagnosis of CMML as defined by the World Health Organization (WHO) criteria
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Impaired renal function",
"treatment": null
}
|
[
0,
0,
3,
0,
0,
0,
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[
"Diagnosis",
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"as",
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"by",
"the",
"World",
"Health",
"Organization",
"(WHO)",
"criteria"
] | null |
NCT02323191
|
23:35:treatment,37:49:treatment,61:82:treatment,94:107:treatment,
|
Prior toxicities from chemotherapy, radiotherapy, and other anti-cancer therapies, including immunotherapy that have not regressed to Grade <=1 severity (Common Terminology Criteria for Adverse Events [CTCAE] v4.03, or later versions)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Crohn's disease",
"treatment": "ustekinumab"
}
|
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[
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"Criteria",
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"v4.03,",
"or",
"later",
"versions)"
] | null |
NCT02479230
|
,,,83:98:cancer
|
Alkaline phosphatase < 2.5 upper limit of normal (ULN) (< 10 x ULN in presence of bone metastases)
|
{
"allergy_name": null,
"cancer": "Tumor",
"chronic_disease": null,
"treatment": null
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|
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[
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"ULN",
"in",
"presence",
"of",
"bone",
"metastases)"
] | null |
NCT02533674
|
27:38:allergy_name
|
Known hypersensitivity to gemcitabine or any component of the formulation
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "hepatitis B",
"treatment": null
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
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[
"Known",
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"gemcitabine",
"or",
"any",
"component",
"of",
"the",
"formulation"
] | null |
NCT02004275
|
14:25:chronic_disease
|
Known active hepatitis C based on
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "human immunodeficiency virus (HIV)",
"treatment": null
}
|
[
0,
0,
2,
2,
0,
0
] |
[
"Known",
"active",
"hepatitis",
"C",
"based",
"on"
] | null |
NCT02498301
|
,94:105:treatment
|
Subject is currently taking or plans to take during deployment at least one of the following medications
|
{
"allergy_name": null,
"cancer": "primary or metastatic brain tumor",
"chronic_disease": null,
"treatment": "tumor resection"
}
|
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0,
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[
"Subject",
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"at",
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"of",
"the",
"following",
"medications"
] | null |
NCT01045148
|
1:16:treatment,21:46:cancer,48:70:treatment,72:93:treatment
|
Radical surgery for carcinoma of the prostate, prior pelvic radiation, pelvic surgical clips or other metallic foreign bodies
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "low molecular-weight heparin"
}
|
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[
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"pelvic",
"surgical",
"clips",
"or",
"other",
"metallic",
"foreign",
"bodies"
] | null |
NCT01130077
|
42:64:treatment
|
Patients in Stratum F must have received craniospinal radiation
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "caffeine"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
1
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[
"Patients",
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"F",
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"received",
"craniospinal",
"radiation"
] | null |
NCT02315196
|
1:20:treatment,56:62:treatment,,149:167:cancer
|
Computed tomography of the chest, abdomen, and pelvis (CT CAP) and bone scan performed within 30 days prior to study entry and does not demonstrate metastatic disease
|
{
"allergy_name": null,
"cancer": "malignant tumor",
"chronic_disease": null,
"treatment": "conventional radiotherapy"
}
|
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] | null |
NCT02460835
|
,,122:128:cancer,,
|
Zubrod performance status of less than or equal to 2 (Zubrod performance status is a measure that attempts to quantify a cancer patients' general well-being. Scores run from 0 to 5 where 0 denotes normal activity and 5 denotes death)
|
{
"allergy_name": null,
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NCT02688647
|
51:54:chronic_disease,51:64:chronic_disease,,129:136:treatment
|
Documented sustained improvement of the subject's IPF condition up to 12 months before study entry with or without IPF-specific therapy
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "suicidal ideation, behavior and attempts",
"treatment": null
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"therapy"
] | null |
NCT03161028
|
1:27:chronic_disease,19:27:chronic_disease,58:83:treatment
|
Insulin-dependent diabetes or diabetes not controlled on oral diabetes medications
|
{
"allergy_name": null,
"cancer": "CNS intracranial tumor",
"chronic_disease": null,
"treatment": null
}
|
[
0,
2,
0,
2,
0,
0,
0,
0,
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[
"Insulin-dependent",
"diabetes",
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"diabetes",
"not",
"controlled",
"on",
"oral",
"diabetes",
"medications"
] | null |
NCT02516696
|
16:52:treatment,,91:106:treatment,118:133:treatment,,194:207:treatment
|
Subject has no prior anti-myeloma treatment therapy within 14 days prior to initiation of study treatment except for corticosteroids with a maximum allowed dosage equivalent to three pulses of dexamethasone (40mg daily for 4 days equals one pulse)
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Lumbar Anterior Fusion",
"treatment": null
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] | null |
NCT02672098
|
21:36:chronic_disease
|
Patients with known acute hepatitis
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "Iron-deficiency anemia",
"treatment": null
}
|
[
0,
0,
0,
0,
2
] |
[
"Patients",
"with",
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"acute",
"hepatitis"
] | null |
NCT02187198
|
44:55:chronic_disease,65:76:chronic_disease,84:98:chronic_disease,100:105:chronic_disease,107:116:chronic_disease,121:138:chronic_disease,149:172:treatment
|
serious unstable medical illness including bradycardia or other arrhythmias, major cardiovascular, renal, endocrine, or hepatic disorders for which buprenorphine treatment is contraindicated or which at the determination of the MD is medically dangerous
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "psychiatric",
"treatment": "weight-affecting medications"
}
|
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] | null |
NCT02509507
|
16:30:treatment,113:123:cancer,128:148:treatment
|
expected other cancer therapy while on study with the exception of local radiation to the site of bone or other metastasis for palliative treatment
|
{
"allergy_name": null,
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"chronic_disease": null,
"treatment": "prior gene transfer therapy"
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0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
1
] |
[
"expected",
"other",
"cancer",
"therapy",
"while",
"on",
"study",
"with",
"the",
"exception",
"of",
"local",
"radiation",
"to",
"the",
"site",
"of",
"bone",
"or",
"other",
"metastasis",
"for",
"palliative",
"treatment"
] | null |
NCT02169037
|
1:23:chronic_disease,50:58:treatment,80:105:chronic_disease,111:132:chronic_disease
|
acquired heart disease that may increase risk of ablation, such as significant ventricular septal defect post myocardial infarction
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": null,
"treatment": "intravenous nitroglycerine"
}
|
[
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
[
"acquired",
"heart",
"disease",
"that",
"may",
"increase",
"risk",
"of",
"ablation,",
"such",
"as",
"significant",
"ventricular",
"septal",
"defect",
"post",
"myocardial",
"infarction"
] | null |
NCT02982226
|
1:16:chronic_disease
|
Fat Pad Atrophy
|
{
"allergy_name": null,
"cancer": null,
"chronic_disease": "cardiac diseases",
"treatment": null
}
|
[
0,
0,
0
] |
[
"Fat",
"Pad",
"Atrophy"
] | null |
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