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NCT02324582 | 1:20:chronic_disease | active tuberculosis | {
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NCT00919503 | 20:40:chronic_disease | DONOR: With active infectious hepatitis | {
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NCT02876302 | 7:10:chronic_disease,59:81:treatment,186:212:treatment | Known HIV-positive individuals who are not on combination antiretroviral therapy are not eligible because these individuals are at increased risk of lethal infections when treated with marrow-suppressive therapy | {
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NCT01573429 | 1:15:treatment,17:30:treatment,32:41:treatment,43:51:treatment,53:67:treatment,69:79:treatment,81:105:treatment,107:120:treatment,122:132:treatment,134:147:treatment,149:160:treatment,165:177:treatment | Salicylic acid, acetaminophen, ibuprofen, naproxen, mefenamic acid, diclofenac, gliclazide carbamazepine, valproic acid, cimetidine, sulfasalazine, amoxicillin and erythromycin | {
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NCT00044304 | ,30:48:treatment | dysplastic megakaryocytes on bone marrow biopsy | {
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NCT01631617 | 8:28:treatment, | Use of systemic antibiotics in 12 months preceding baseline sampling | {
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NCT02268253 | ,,,171:186:treatment | agrees to use acceptable contraceptive methods for the duration of time in the study, and to continue to use acceptable contraceptive methods for 2 months after the last SL-401 infusion | {
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NCT02203513 | 72:83:treatment, | Patients must have normal organ and marrow function (in the absence of transfusion 24 hours prior to dosing) | {
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NCT02596776 | ,,,,,,117:121:chronic_disease | Insulin resistance Fasting blood sugar >126, or 2 hr glu >200, but with A1C<7.5 (i.e. we will include subjects with T2DM on no meds and with good glycemic control) | {
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NCT02830360 | ,16:19:treatment | ≥1 appropriate ICD shocks | {
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NCT01430390 | 25:35:treatment | Donor's high resolution HLA typing must be available for review | {
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NCT03120728 | 27:65:chronic_disease | multiple risk factors for atherosclerotic cardiovascular disease | {
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NCT02540330 | 16:25:chronic_disease,36:47:chronic_disease,52:69:chronic_disease | Presence of an infection including ulcerations and fungal infections in the breast to be studied | {
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NCT02796209 | 1:25:chronic_disease | Congestive heart failure | {
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NCT01351103 | 1:19:treatment,66:73:cancer,84:125:treatment,118:125:treatment,170:189:chronic_disease,217:225:cancer,227:235:cancer,237:242:cancer,258:272:cancer,274:286:cancer,290:294:cancer,341:364:treatment | LGK974 with PDR001: Dose escalation: patients with the following cancers that were previously treated with anti-PD-1 therapy and whose best response on that therapy was progressive disease (i.e. primary refractory): melanoma, lung SCC, HNSCC. Patients with esophageal SCC, cervical SCC or TNBC who are either naïve or pr... | {
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NCT01951885 | 31:85:treatment | Patients must be undergoing a myeloablative allogeneic hematopoietic cell transplant with one of the following conditioning regimens | {
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NCT02515773 | 23:40:chronic_disease,81:96:chronic_disease,111:130:treatment,185:202:chronic_disease,204:211:treatment,214:235:chronic_disease,237:245:treatment | Major neurological or medical illnesses that affect weight gain (e.g., unstable thyroid disease) or require a systemic medication that might impact weight or glucose regulation (e.g., diabetes mellitus [insulin], chronic renal failure [steroids]) | {
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NCT02496208 | 1:18:chronic_disease | Abdominal fistula | {
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NCT02671435 | 1:40:treatment | Prior treatment with antitumor vaccines may be permitted upon discussion with the medical monitor | {
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NCT02561988 | 12:23:treatment,31:39:chronic_disease,41:50:chronic_disease,55:62:treatment | reason for transfusion is not bleeding, hemolysis, or therapy-related | {
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NCT01976585 | ,,,180:190:treatment | Patients of reproductive potential and their partners must agree to use an effective (> 90% reliability) form of contraception during the study and for 4 weeks following the last study drug administration | {
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NCT02176902 | 15:30:treatment,62:76:treatment,85:115:cancer | Patient had a prostate biopsy performed by Dr. Mark with the Artemis device and has adenocarcinoma of the prostate | {
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NCT02226341 | 14:48:chronic_disease | Diagnosis of Systemic Lupus Erythematosus (SLE) by American College of Rheumatology (ACR)/SLICC criteria | {
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NCT02570984 | 12:45:chronic_disease | History of severe anaphylactic/anaphylactoid reactions from any cause | {
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NCT02100722 | 13:18:chronic_disease | Ongoing Non STEMI with biomarkers (cardiac troponin) still rising | {
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NCT01884740 | 1:16:treatment, | Minor surgeries may be performed after two weeks | {
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NCT01639508 | ,,87:102:treatment,110:118:chronic_disease,156:159:chronic_disease | The subject has not recovered to baseline or CTCAE ≤ Grade 1 from toxicity due to all prior therapies except alopecia and other non-clinically significant AEs | {
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NCT01983462 | 15:37:chronic_disease,45:57:chronic_disease,59:65:chronic_disease,67:80:chronic_disease,82:104:chronic_disease,106:120:chronic_disease,123:129:chronic_disease,133:148:chronic_disease,153:180:chronic_disease | No history of cardiovascular disease (e.g., heart attack, stroke, heart failure, valvular heart disease, cardiomyopathy), Type 1 or Type 2 diabetes, or peripheral arterial disease | {
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NCT02506192 | 8:32:chronic_disease | Has an chronic/active infection | {
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NCT01961778 | 25:45:treatment,49:73:cancer,79:105:cancer,119:150:cancer | suitable candidates for endoscopic treatment of Barrett's esophagus (BE) with high-grade dysplasia (HGD) and/or early adenocarcinoma of the esophagus | {
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NCT02252081 | 1:28:chronic_disease | Decompensated heart failure | {
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NCT02669173 | 1:4:chronic_disease,26:60:treatment,139:151:treatment,159:170:treatment | HIV-positive subjects on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with capecitabine and/or bevacizumab | {
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NCT02498535 | 1:29:treatment, | Intravenous or oral steroids in the 14 days prior to screening | {
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NCT01851369 | ,,72:82:treatment,72:83:treatment,219:228:treatment | Pregnant women are excluded from this study because the effects of the study drugs on the developing fetus are unknown. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with the study drugs, breastfeeding should be discontinued prior to the first ... | {
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NCT02169089 | 24:48:chronic_disease | History of any severe, life-threatening disease | {
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NCT02913495 | 10:26:chronic_disease | clinical chorioamnionitis, at the time of enrollment | {
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NCT01880567 | 17:20:cancer,, | Newly diagnosed MCL: Patients with bi-dimensional measurable disease with a tumor >= 10 cm | {
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NCT01793519 | 17:40:treatment, | Treated with an investigational RA drug in the last 6 months | {
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NCT02487082 | 1:21:chronic_disease | Peptic ulcer disease | {
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NCT02389309 | 32:64:allergy_name | History of hypersensitivity to any component of the formulation | {
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NCT01422746 | 45:59:chronic_disease, | Subjects with stable and adequately treated hypothyroidism, reflected by normal TSH values | {
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NCT02389309 | 61:83:chronic_disease,94:106:treatment,117:136:treatment,138:157:chronic_disease | Uncontrolled current illness including, but not limited to, uncontrolled infection, need for hemodialysis, need for ventilatory support, psychiatric illness/social situations that would limit compliance with study requirements | {
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NCT02860702 | 82:97:treatment | Outborn infants who received enteral nutrition at the other institution prior to surgical repair | {
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NCT01599559 | 36:51:chronic_disease,103:126:chronic_disease,128:152:chronic_disease | Evidence of clinically significant cardiac disease at diagnosis, as defined by history of symptomatic ventricular arrhythmias, congestive heart failure | {
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NCT02562066 | 1:17:chronic_disease | Seizure disorder | {
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NCT02180243 | 24:50:chronic_disease,57:64:chronic_disease,66:70:chronic_disease,72:92:chronic_disease | Currently suffers from Gulf War Veterans' Illness (i.e. fatigue, pain, cognitive impairment) | {
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NCT02876510 | 32:48:allergy_name,50:61:allergy_name,65:69:allergy_name | History of hypersensitivity to cyclophosphamide, fludarabine or IL-2 | {
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NCT02012296 | 18:30:cancer | History of other malignancies | {
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NCT02880215 | 28:50:chronic_disease | meets criteria for current substance use disorder (mild or greater severity) | {
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NCT01970345 | 23:28:allergy_name | History of allergy to IGF-1 | {
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NCT02208362 | 85:98:treatment | Research participants being treated for severe infection or who are recovering from major surgery | {
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NCT02058095 | 1:9:treatment | Prazosin | {
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NCT02166905 | 31:65:treatment,60:64:treatment,118:128:treatment,130:139:treatment,141:155:treatment, | Subjects being treated with a monoamine oxidase inhibitor (MAOI), or drug which has significant MAOI activity (e.g., Meperidine, linezolid, methylene blue) within 3 weeks prior to screening | {
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NCT02050113 | 20:28:treatment | High risk for open surgical repair based on any of the factors | {
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NCT03084640 | 1:16:cancer | Ocular melanoma participants | {
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NCT01589263 | 5:32:treatment,43:81:treatment,86:89:chronic_disease | Any prior surgical intervention or use of 5-alpha-reductase medical intervention for BPH | {
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NCT01972919 | ,,41:52:treatment, | Hemoglobin ≥ 8.0 g/dl (Note: The use of transfusion or other intervention to achieve Hgb ≥ 8.0 g/dl is acceptable.) | {
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NCT02304458 | 47:67:cancer | Part B6: patients with relapsed or refractory non-Hodgkin lymphoma | {
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NCT03115424 | 16:35:chronic_disease | Active, severe psychiatric disease | {
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NCT02088554 | 18:35:treatment | Patient requires emergency surgery | {
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NCT01871727 | 15:28:cancer | Lead-In Part: Stage IA - IV, except participants with CNS involvement | {
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NCT01742299 | 42:65:treatment | Patient is currently benefiting from the treatment with imatinib, as determined by the investigator | {
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NCT02515773 | 70:102:chronic_disease | Diagnosed or told by a clinician that they have any of the following bipolar spectrum disorders (BSD) | {
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NCT02088554 | 16:38:chronic_disease | Patient has an anatomical abnormality which would increase surgical risk of morbidity or mortality | {
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NCT02715583 | 1:23:treatment, | Cytotoxic chemotherapy within 4 weeks prior to study enrollment | {
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NCT01365169 | 20:43:chronic_disease,34:43:chronic_disease,57:63:cancer,108:127:chronic_disease | History of current oropharyngeal dysphagia unrelated to cancer diagnosis (e.g. dysphagia due to underlying neurogenic disorder) (Arm 3 only) | {
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NCT02402660 | 7:22:chronic_disease | other retinal disease | {
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NCT02338999 | 25:37:allergy_name | Known latex allergy for EndoPAT test | {
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NCT02203513 | 75:103:cancer,107:145:cancer,192:205:cancer | Patients enrolling in Cohort 6, the recurrent platinum-resistant sporadic high grade serous epithelial or high grade endometrioid ovarian cancer group, must have a negative family history of HBOC syndrome, or negative gBRCA1/2m test | {
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NCT02661386 | 20:41:chronic_disease,56:76:chronic_disease,78:105:treatment,107:132:chronic_disease,134:152:chronic_disease,154:163:chronic_disease | Known or suspected Zenker's diverticulum of esophagus, esophageal stricture, head/neck radiation therapy, hereditary telangiectasis, esophageal varices, cirrhosis | {
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NCT01524536 | ,42:52:treatment, | Receiving less than or equal to 10 mg of prednisone or equivalent but have not been on a fixed dose for at least 3 weeks | {
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NCT01434316 | ,,38:55:treatment, | Hemoglobin (Hgb) > 10.0 g/dL with no blood transfusion in the past 28 day | {
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NCT02301663 | 1:9:chronic_disease | Diabetes | {
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"Diabetes"
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NCT02744430 | 15:43:chronic_disease | Patients with Childs B and C liver failure | {
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NCT02233322 | 18:27:treatment,33:42:treatment,47:57:treatment,149:173:chronic_disease | May be receiving treatment with phosphate and calcitriol, but must be willing to undergo dose adjustments by the investigators if iron resolves the phosphate wasting defect | {
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NCT02765633 | 18:27:allergy_name | Known allergy to cangrelor or known sensitivity to any component of cangrelor | {
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NCT02111850 | ,,73:83:treatment | Absolute neutrophil count greater than 1000/mm^3 without the support of filgrastim | {
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NCT02466685 | 1:32:treatment, | Antidepressant (AD) medications are allowed if the subject has been treated with a stable dose for at least 2 months before screening | {
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NCT01238120 | 7:28:chronic_disease, | Had a myocardial infraction within the past 6 months | {
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NCT02877381 | 23:44:chronic_disease, | major co-morbidities (myocardial infarction or stent placement within one year | {
"allergy_name": null,
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"chronic_disease": "myocardial infarction",
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NCT03078504 | 1:28:treatment | therapeutic anticoagulation being administered | {
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"treatment": "therapeutic anticoagulation"
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NCT01494662 | 41:44:treatment,62:71:treatment,73:81:treatment | Patients with known contraindication to MRI, such as cardiac pacemaker, shrapnel, or ocular foreign body | {
"allergy_name": null,
"cancer": "pancreatic cancer",
"chronic_disease": null,
"treatment": "investigational therapy"
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NCT03113136 | 12:37:chronic_disease, | history of cardiac event or distress within the past 3 months | {
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"chronic_disease": "cardiac event or distress",
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NCT02374021 | 1:35:chronic_disease | Systemic lupus erythematosus (SLE) | {
"allergy_name": null,
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"chronic_disease": "Systemic lupus erythematosus (SLE)",
"treatment": null
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0,
0
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] | null |
NCT02276443 | ,,,68:81:chronic_disease,97:118:chronic_disease,120:135:chronic_disease,139:169:chronic_disease, | Patients with a history of New York Heart Association class 3 or 4 heart failure, or history of myocardial infarction, unstable angina or cerebrovascular accident (CVA) within 6 months of protocol registration | {
"allergy_name": null,
"cancer": null,
"chronic_disease": "cerebrovascular accident (CVA)",
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... | null |
NCT02496208 | 12:28:treatment | History of organ transplant | {
"allergy_name": null,
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"treatment": "organ transplant"
} | [
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NCT02120222 | 8:31:chronic_disease | HBsAg (hepatitis B virus [HBV] surface antigen) | {
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NCT02516332 | 10:19:treatment | Complete Pacemaker dependence | {
"allergy_name": null,
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"treatment": "Pacemaker"
} | [
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1,
0
] | [
"Complete",
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] | null |
NCT02784535 | 1:22:chronic_disease | Narrow-angle glaucoma | {
"allergy_name": null,
"cancer": null,
"chronic_disease": "Narrow-angle glaucoma",
"treatment": null
} | [
0,
0
] | [
"Narrow-angle",
"glaucoma"
] | null |
NCT02346253 | 12:26:chronic_disease | History of rectal fistula | {
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"chronic_disease": "rectal fistula",
"treatment": null
} | [
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0,
0,
2
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"History",
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NCT02338999 | 16:40:treatment,, | Receipt of any investigational new drug or device within 30 days prior to screening or 5 half-lives of the agent <TAB>(whichever is longer), or any investigational new drug with known long-term effects | {
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"treatment": "investigational new drug"
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NCT02595866 | 18:31:chronic_disease,54:70:cancer,90:112:cancer,136:157:cancer | Extensive active brain disease including symptomatic brain metastases or the presence of leptomeningeal disease, and all patients with infratentorial tumors | {
"allergy_name": null,
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NCT02597985 | 1:24:chronic_disease | Acute coronary syndrome | {
"allergy_name": null,
"cancer": null,
"chronic_disease": "Acute coronary syndrome",
"treatment": null
} | [
0,
0,
2
] | [
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NCT00734877 | 24:54:chronic_disease,, | Patients must not have light chain deposition disease or creatinine > 3 mg/dl | {
"allergy_name": null,
"cancer": null,
"chronic_disease": "light chain deposition disease",
"treatment": null
} | [
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