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How many yards does the loss of down lose on third down? | Context: During the last three minutes of a half, the penalty for failure to place the ball in play within the 20-second play clock, known as "time count" (this foul is known as "delay of game" in American football), is dramatically different from during the first 27 minutes. Instead of the penalty being 5 yards with t... |
On what down can the 20 second play clock give possession to the defense? | Context: During the last three minutes of a half, the penalty for failure to place the ball in play within the 20-second play clock, known as "time count" (this foul is known as "delay of game" in American football), is dramatically different from during the first 27 minutes. Instead of the penalty being 5 yards with t... |
What happens to a quarter whose time expires while the ball is still live in play? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
What causes a quarter to be extended one additional play even if time has run out? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
How long is a quarter in minutes? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
Which plays do not cause time to run off the clock during the final minutes of a half? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
When does the clock not run when a penalty is pending? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
If a quarter's time expires while the ball is pending how long is the quarter extended? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
When can't a scrimmage end? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
What does the losing team have the option to do? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
What is the name of the plays where the clock doesn't run near the end of a half? | Context: The clock does not run during convert attempts in the last three minutes of a half. If the 15 minutes of a quarter expire while the ball is live, the quarter is extended until the ball becomes dead. If a quarter's time expires while the ball is dead, the quarter is extended for one more scrimmage. A quarter ca... |
What determines which team gets possession first when extending a game to break a tie? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
At which yard line on their opponent's side does a team take possession of the ball according to the CFL's tie-breaking rules? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
In which year did the CFL begin requiring teams to attempt 2-point conversions after scoring in a tie-breaking situation? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
Which round of tie-breaking is the last possible round in a regular season CFL game? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
Which CFL games require tie-breaking rounds continue until a winner results? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
After teams have completed their 2 point conversions, who is declared the winner? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
If a game is tied at the end of a touchdown, what determines who takes possession? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
After the coin toss if there is no winner during regular season what happens? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
What is a team required to do after having a possession in the 2010 season? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
In the 2010 season if a game is tied what can each team do? | Context: In the CFL, if the game is tied at the end of regulation play, then each team is given an equal number of chances to break the tie. A coin toss is held to determine which team will take possession first; the first team scrimmages the ball at the opponent's 35-yard line and advances through a series of downs un... |
Who identified the active substance? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who marketed epinephrine? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
As an inhaler, what was epinephrine used to treat? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who developed the method to obtain epinephrine in a pure state? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
What could epinephrine treat? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
When did epinephrine stop being available in the United States? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
What trade name was epinephrine marketed under? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who developed the method to get epinephrine in it's pure form? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
In what year was epinephrine discovered? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
What was the trade name of epinephrine? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who first discovered epinephrine? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
What is epinephrine used to treat? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
In what year was Primatene Mist no longer sold in the United States? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who identified the inactive substance? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who marketed Primatene? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
What trade name was Primatene marketed under? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
As an inhaler, what was Primatene used to treat? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who developed the method to obtain Primatene in a pure state? | Context: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adre... |
Who developed Amphetamine? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What are common side effects of Amphetamine? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
When were tricyclic antidepressants developed? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What were some uses for Amphetamine? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
Who synthesized Amphetamine for asthma? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
Ephedrine was used as an oral medicine for what illness? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
In what year was amphetamine first tested on asthma patients? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What was the trade name of amphetamine as a nasal decongestant? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
In what year did the American Medical Association approve amphetamine for medical use? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
In what decade were tricyclic antidepressants created? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
Who developed tricyclics? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What are common side effects of tricyclics? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
When was the American Medical Association developed? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What were some uses for the American Medical Association? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
Who synthesized the American Medical Association for asthma? | Context: While highly effective, the requirement for injection limited the use of norepinephrine[clarification needed] and orally active derivatives were sought. A structurally similar compound, ephedrine, was identified by Japanese chemists in the Ma Huang plant and marketed by Eli Lilly as an oral treatment for asthm... |
What is diabetes caused from? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Before insulin, what was the life expectancy of diabetics? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
How can diabetes be induced in dogs? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Who discovered that pancreatic extract reversed symptoms of pancreas removal? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Why was insulin therapy delayed? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Diabetes is caused by the removal of what organ? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Left untreated, how long were diabetic patients were expected to live? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
What could be adjusted in a sample of pancreatic extract to produce purer insulin? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
To purify insulin, Banting and Best sought the assistance of what company? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Minkowski and von Mering did surgical tests on what animal? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
What is purification caused from? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Before insulin, what was the life expectancy of purification? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
How can purification be induced in dogs? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Who discovered that pancreatic extract reversed symptoms of purification removal? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
Why was purification therapy delayed? | Context: A series of experiments performed from the late 1800s to the early 1900s revealed that diabetes is caused by the absence of a substance normally produced by the pancreas. In 1869, Oskar Minkowski and Joseph von Mering found that diabetes could be induced in dogs by surgical removal of the pancreas. In 1921, Ca... |
What is phenobarbital used for? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What sleep aid was marketed in 1904? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What is amphetamine used for today? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
Why was barbiturates and amphetamines restricted? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
Who discovered a reaction that induced sleep in dogs? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What compound was discovered to induce sleep? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What was the first trade name of diethylbarbituric acid? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What is phenobarbital mainly used to treat today? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
In what year was phenobarbital discovered? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What was Veronal used for when Bayer put it on the market? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What is increased awareness used for? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What acid was marketed in 1904? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
What is acid used for today? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
Why were acids restricted? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
Who discovered an acid reaction? | Context: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under ... |
Who developed Arsphenamine? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What was the first effective treatment for Syphilis? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What complications are associated with Syphilis? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What is Amphetamine's market name? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
Where is the Institute of Experimental Therapy located? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What was the name of the first synthetic bacterial drug? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
Bacterial infections could be treated with medicines containing what kind of dye? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
Arsphenamine became the first treatment for what previously incurable disease? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
In what year was arsphenamine discovered? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What was the commercial name of arsphenamine? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
Who developed commercial ulceration? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What was the first effective treatment for Bertheim? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What complications are associated with Bertheim? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
What is Bertheim's market name? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
Where is the Institute of Bertheim located? | Context: In 1911 arsphenamine, the first synthetic anti-infective drug, was developed by Paul Ehrlich and chemist Alfred Bertheim of the Institute of Experimental Therapy in Berlin. The drug was given the commercial name Salvarsan. Ehrlich, noting both the general toxicity of arsenic and the selective absorption of cer... |
When was Morphine and Quinine first available? | Context: The modern pharmaceutical industry traces its roots to two sources. The first of these were local apothecaries that expanded from their traditional role distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid 1800s. Rational drug discovery from plants started particularly ... |
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