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A comparison of stability and clinical outcomes in single-radius versus multi-radius femoral design for total knee arthroplasty
We compared the intraoperative varus-valgus stability from 0° to 90° of flexion and postoperative clinical outcomes in patients receiving TKA via either a single-radius femoral design (50 TKA, SR group) or multi-radius femoral design (50 TKA, MR group). We measured stabilities at 0°, 30°, 60° and 90° of flexion u...
Fracture mechanisms and fracture pattern in men and women aged 50 years and older: a study of a 12-year population-based injury register, Umea, Sweden
In a study of a 12-year population-based injury register, Umea, Sweden, we analyzed the fracture mechanisms and fracture pattern in men and women 50 years and older. Low-energy trauma was responsible for the major and costliest part of the fracture panorama, but the pattern differs between age groups. INTRODUCTION: Ost...
Evaluation and management of leg problems in the runner
Stress fractures, the medial tibial syndrome (shin splints), Achilles tendinitis, chronic compartment syndromes, the popliteal artery entrapment syndrome, and deep venous thrombosis are discussed. Attention is directed to the pathogenesis, diagnosis, treatment, and prognosis for these conditions.
Obesity, overweight and patterns of osteoarthritis: the Ulm Osteoarthritis Study
The objective of this study was to assess the association between obesity and osteoarthritis (OA) of the knee, hip, and hand. OA patterns were studied in 809 patients with knee or hip joint replacement due to OA. Patients with OA were categorized as having bilateral or generalized OA according to the presence of radiog...
Floppy eyelid syndrome: a modified surgical technique
PURPOSE: To describe and present the results of a modified surgical technique to repair floppy eyelids. METHODS: A case series of 5 patients who were treated with the modified technique is presented. This technique uses the relaxed skin tension lines to tighten the lids in an aesthetically minded reconstruction. RESULT...
Efficacy of adductor canal block following knee surgery: A systematic review
Background and Goal of Study: Knee surgery is associated with significant postoperative pain. Adductor canal block (ACB), predominantly a sensory block involving the saphenous nerve, nerve to vastus medialis and the articular branch of obturator nerve1 , reduces postoperative pain after knee surgery but there is confli...
Treatment of distal biceps tendon rupture: why, when, how? Analysis of literature and our experience
INTRODUCTION: The rupture of the distal biceps tendon is a relatively uncommon lesion. Even if conservative treatment may be an option in low demanding patients, young and active subjects may benefit from an early surgical reinsertion. Many techniques and fixation devices have been described, but in the literature, the...
Outcomes After the Operative Treatment of Bucket-Handle Meniscal Tears in Children and Adolescents
Background: Bucket-handle meniscal tears (BHMTs), which we define as vertical longitudinal tears of the meniscus with displacement of the torn inner fragment toward the intercondylar notch region, are a well-recognized tear pattern. Optimizing the management of BHMTs in younger patients is important, as preserving meni...
Single injection of high volume of autologous pure PRP provides a significant improvement in knee osteoarthritis: A prospective routine care study
Background: Evidence is growing regarding the ability of platelet-rich plasma (PRP) injections to enhance functional capacity and alleviate pain in knee osteoarthritis (OA). However, heterogeneity in common practice regarding PRP preparation and biological content makes the initiation of this activity in a hospital com...
Septic arthritis
This article describes the aetiology, diagnosis and treatment of pyogenic septic arthritis. The epidemiology is described and the at-risk groups delineated. The difficulties with current diagnostic methods are highlighted and controversies regarding optimal management raised. A list of pivotal articles is included
Cost-effectiveness and economic impact of the KineSpring® Knee Implant System in the treatment of knee osteoarthritis in the United Kingdom
Knee osteoarthritis (OA) is a condition affecting 8.5 million individuals in the United Kingdom (UK). Although many treatment options are available, there is a need for a less-invasive treatment for individuals with mild to moderate knee OA. The purpose of the present study was to determine whether the KineSpring Syste...
Occurrence and incidence of the second hip fracture
During a 16-year period, 256 second hip fractures were found in 3898 persons 40 years of age and older who had a previous hip fracture. Ninety-two percent of the second fractures were contralateral, and 68% of these were the same type as the first. Thus, 62% of the femoral neck and 72% of the trochanteric fractures wer...
Exercise in knee osteoarthritis--preliminary findings: Exercise-induced pain and health status differs between drop-outs and retainers
BACKGROUND: Exercise effectiveness is related to adherence, compliance and drop-out. The aim of this study is to investigate if exercise-induced pain and health status are related to these outcomes during two exercise programs in knee osteoarthritis patients. METHODS: Symptomatic knee osteoarthritis patients were rando...
Treatment of posttraumatic varus ankle deformity with supramalleolar osteotomy
Supramalleolar osteotomies for correction of posttraumatic varus arthritis in early and mid-stages provide good functional and clinical outcomes. However, the biomechanical behavior of the ankle joint differs from the knee, and therefore correction of the distal TAS angle alone may not provide a physiologic load transf...
Sialolithiasis. Ultrastructural morphology and bacterial etiology
Twenty-five salivary calculi, most of them formed in the submandibular gland, were subjected to scanning electron microscopic study to determine their microstructure and investigate possible bacterial colonization. Hydroxyapatite was the most common crystalline component, with up to 7 different forms of crystallization...
Midterm clinical results of osteochondral autograft transplantation for advanced stage Freiberg disease
PURPOSE: We aimed to evaluate the midterm clinical results of osteochondral autograft transplantation (OAT) for advanced stage Freiberg disease. METHODS: This study included consecutive patients who underwent OAT for advanced stage Freiberg disease and were followed postoperatively for more than five years. In all case...
Transcranial direct current stimulation of SMA modulates anticipatory postural adjustments without affecting the primary movement
Recent works provide evidences that anticipatory postural adjustments (APAs) are programmed with the prime mover recruitment as a shared posturo-focal command. However the ability of the CNS to adjust APAs to changes in the postural context implies that the postural and voluntary components should take different pathwa...
Bone mass, muscle function and fracture of the proximal femur
The epidemiology and pathogenesis of hip fractures are reviewed. There is evidence that physical inactivity and concomitant muscle weakness are important determinants of the risk of hip fracture
Condylocephalic nails versus extramedullary implants for extracapsular hip fractures
BACKGROUND: Two types of implants used for the surgical fixation of extracapsular hip fractures are condylocephalic nails (intramedullary nails that are inserted up through the femoral canal from above the knee and across the fracture) and extramedullary implants. OBJECTIVES: To compare condylocephalic nails (e.g. Ende...
Uncemented porous tantalum acetabular components: Early follow-up and failures in 613 primary total hip arthroplasties
Uncemented tantalum acetabular components were introduced in 1997. The purpose was to determine the 2- to 10-year results with this implant material in primary total hip arthroplasty. Our registry identified all primary total hip cases with porous tantalum cups implanted from 1997 to 2004. Clinical outcomes and radiogr...
Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis
BACKGROUND: Onchocerciasis, also known as "river blindness," is a parasitic disease that is caused by infection from the filarial nematode (roundworm), Onchocerca volvulus. Nematodes are transmitted from person to person by blackflies of the Simulium genus, which usually breed in fast flowing streams and rivers. The di...
Bone Health in Duchenne Muscular Dystrophy- a case controlled study of Risedronate use - Risedronate in DMD
INTERVENTION: Trade Name: Actonel Once a week 5mg film coated tablets Product Name: Risedronate sodium Product Code: Risedronate Pharmaceutical Form: Film�coated tablet Trade Name: Calcichew D3 Forte Product Name: Calcichew D3 Forte Product Code: Calcichew D3 Forte Pharmaceutical Form: Chewable tablet CONDITION: Bone...
Urinary calculi in hypercalcemic states
In this brief review of various hypercalcemic disorders and the likelihood of renal calculus formation, it is clearly evident that renal calculi occur much more often in hyperparathyroidism than in the other hypercalcemic states. Dystrophic calcification and nephrocalcinosis are common to all of the hypercalcemic disor...
Infected nonunion of tibia and femur treated by bone transport
OBJECTIVE: The objective of this study was to evaluate the effectiveness of the treatment of infected nonunion of tibia and femur by bone transport. MATERIAL AND METHODS: We retrospectively reviewed 110 patients with infected nonunion of tibia and femur treated by bone transport. Our study included 92 males and 18 fema...
Proximal tibial bone density is preserved after unicompartmental knee arthroplasty knee
Background: Bone mineral density (BMD) in the proximal tibia decreases after TKA and is believed to be a factor in implant migration and loosening. Unicompartmental knee arthroplasty (UKA) is a less invasive procedure preserving knee compartments unaffected by degeneration. Finite element studies have suggested UKA may...
Prospective Results of Uncemented Tantalum Monoblock Tibia in Total Knee Arthroplasty. Minimum 5-Year Follow-up in Patients Younger Than 55 Years
A significant increase in younger patients undergoing total knee arthroplasty raises the theoretical concern for revision secondary to micromotion and fixation failure with cemented components. We prospectively studied 100 consecutive tantalum monoblock uncemented tibial components and 312 concurrent cemented controls....
The effects of various physical non-operative modalities on the pain in osteoarthritis of the knee
The purpose of this study was to evaluate the effect of various non-operative modalities of treatment (transcutaneous electrical nerve stimulation (TENS); neuromuscular electrical stimulation (NMES); insoles and bracing) on the pain of osteoarthritis (OA) of the knee. We conducted a systematic review according to the P...
Reliability of using radius union scoring system among general practitioners, orthopedic residents and orthopedic surgeons for distal end radius fracture healing evaluation
Background: Fractures of distal end of radius are common fractures in adults. They were commonly treated by general practitioners (GPs) in rural Thailand. Inadequate time for immobilization and casting may reach more complications such as failure to maintain reduction or stiffness. There has been no publication of obje...
Impact of obesity on disability, function, and physical activity: data from the Osteoarthritis Initiative
OBJECTIVES: Older adults with obesity are at risk for osteoarthritis (OA) and are predisposed to functional decline and disability. We examined the association between obesity and disability, physical activity, and quality of life at 6 years. METHOD: Using data from the longitudinal Osteoarthritis Initiative (OAI), we ...
Treatment of undisplaced femoral neck fractures in the elderly
BACKGROUND: While the treatment for displaced femoral neck fractures in the elderly (Garden types III and IV) is quite clear, the procedure for impacted or undisplaced femoral neck fractures (Garden types I and II) is still a subject of controversy. Methods: Thirty-seven (all >80 years old) patients with undisplaced fe...
Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
The investigators propose to prospectively randomize orthopedists, with their patients, to receive (or not) a real�time, web�based system intervention: the OA Care plan. The OA Care plan will include individualized, patient�centric information: (1) trended patient�reported OA pain and function, (2) tailored est...
A review of 100 cases of supracondylar fractures in children seen in Ibadan
Supracondylar fracture of the humerus in children is one of the commonest fractures in children of school age all over the world. The experience of the mode of presentation, mechanism of injury and the different modalities of treatment in the University College Hospital, Ibadan is presented. The results suggest that se...
Preoperative oral administration of fast-release morphine sulfate reduces postoperative piritramide consumption
The aim of this prospective randomized placebo-controlled double-blind study was to investigate the effect of premedication with morphine sulfate on postoperative pain. Ninety-eight ASA I-III patients undergoing total replacement of the knee or hip joint were randomly assigned to one of two groups. Group 1 received 20 ...
Three-dimensional variations in the lower limb caused by the windlass mechanism
BACKGROUND: The windlass mechanism was described as the effect caused by the extension of the first metatarsalphalangeal joint (1st MTPJ). Quantify the degrees of movement produced in the leg by means of the Bioval® sensor system, after performing two measurements in the 1st MTPJ, 45° extension and maximum extension....
Localization of regional lymph nodes in melanomas of the head and neck
Objectives: To study the efficacy of gamma-probe radiolocalization of the first draining (sentinel) lymph node (SLN) in stage NO melanoma of the head an neck and to evaluate its potential role in the staging and treatment of this disease. Design: Gamma-probe radiolocalization, a new alternative to blue-dye lymphatic ma...
Seasonal variation in the incidence of hip fractures in Emilia-Romagna and Parma
Though some reports suggest the existence of seasonal changes in hip fracture incidence, with a peak in winter months, other investigations have failed to confirm this finding. In this study we present data on the month-to-month variability of hip fractures in Emilia-Romagna, a region of Northern Italy with a populatio...
MDCT evaluation of pancreatic contour variations in head, neck, body and tail: surgical and radiological significance
OBJECTIVE: The purpose of the study was to investigate the incidence of pancreatic contour variations on multidetector CT (MDCT) for abdominal examinations. METHODS: A retrospective analysis of 700 MDCT scans was performed in patients who underwent triple phase CT abdomen between October 2018 and January 2021. After ex...
Running Dose and Risk of Developing Lower-Extremity Osteoarthritis
Whether or not running leads to the development of knee and hip osteoarthritis has been a much-debated topic and is often a question patients pose to their physicians. Recent literature adds to a growing body of evidence suggesting that lower-dose running may be protective against the development of osteoarthritis, whe...
Preoperative morphometric differences in the distal femur are based on skeletal size in Japanese patients undergoing total knee arthroplasty
PURPOSE: The objectives of this study were to measure the morphometric parameters of preoperative distal femurs to determine the differences by diagnosis and gender after accounting for skeletal size. METHODS: One-hundred and seventy-nine Japanese patients who underwent total knee arthroplasty (TKA) (25 males and 154 f...
Unipolar versus bipolar Exeter hip hemiarthroplasty: a prospective cohort study on 830 consecutive hips in patients with femoral neck fractures
BACKGROUND: Hip replacement using a hemiarthroplasty (HA) is a common surgical procedure in elderly patients with fractures of the femoral neck. Data from the Swedish Hip Arthroplasty Register suggest that there is a higher risk for revision surgery with the bipolar HA compared with the unipolar HA. PURPOSE: In this st...
Does concomitant breast surgery add morbidity to abdominoplasty?
BACKGROUND: Patients undergoing abdominoplasty often have breast concerns, as well as abdominal concerns, because pregnancy is often the etiologic factor in both. Although concerns about combination procedures have been raised recently, the specific issue of combining abdominoplasty and breast surgery has been scarcely...
Metachondromatosis: more than just multiple osteochondromas
INTRODUCTION: Metachondromatosis is a rare genetic disease of osteochondroma and enchondroma formation, caused by loss of function of the PTPN11 gene. It is distinct from other similar conditions such as multiple osteochondromas and hereditary multiple exostoses by the distribution and orientation of lesions, and patte...
Automatic detection of landmarks for the analysis of a reduction of supracondylar fractures of the humerus
An accurate identification of bone features is required by modern orthopedics to improve patient recovery. The analysis of landmarks enables the planning of a fracture reduction surgery, designing prostheses or fixation devices, and showing deformities accurately. The recognition of these features was previously perfor...
Subchondral Calcium Phosphate is Ineffective for Bone Marrow Edema Lesions in Adults With Advanced Osteoarthritis
BACKGROUND: Injury to subchondral bone is associated with knee pain and osteoarthritis (OA). A percutaneous calcium phosphate injection is a novel approach in which subchondral bone marrow edema lesions are percutaneously injected with calcium phosphate. In theory, calcium phosphate provides structural support while it...
Dietary Supplement-Drug Interaction-Induced Serotonin Syndrome Progressing to Acute Compartment Syndrome
BACKGROUND Dietary supplements have been associated with an increase in emergency intervention as a result of unexpected adverse events. Limited resources and information on significant drug-drug interactions with dietary supplements and prescription medications have contributed to associated complications and unexpect...
Early Experience With Body Contouring Procedures in Patients With End-Stage Renal Disease Awaiting Renal Transplant
INTRODUCTION: Patients with (end-stage renal disease) ESRD often have many medical comorbidities, posing a higher risk for any surgical procedure. Obese patients are asked to lose weight to become more acceptable renal transplant candidates. Unfortunately, this often results in a panniculus and excess ptotic skin with ...
Proximal femoral allograft: prognostic indicators
Between 1972 and 1999, the Orthopedic Oncology Service treated 150 patients with resection and allograft transplantation of the proximal femur. Of the group, 121 patients had malignant tumors of the proximal femur and 29 had benign disorders. Four types of allografts were used: osteoarticular (46 patients), allograft-p...
The sex-specific influence of quadriceps weakness on worsening patellofemoral and tibiofemoral cartilage damage: the MOST Study
OBJECTIVE: Reports on quadriceps weakness as a risk factor for incident and progressive knee osteoarthritis are conflicting, potentially due to differing effects of muscle strength on patellofemoral and tibiofemoral compartments. This study aimed to examine the sex-specific relation of quadriceps strength to worsening ...
Osteochondral lesions of the knee reconstructed with mesenchymal stem cells - results
BACKGROUND: We present the results of the treatment of osteochondral lesions with the modified sandwich technique with a collagen membrane. The aim of the study was to assess and compare clinical outcomes following the reconstruction of osteochondral lesions in two groups of patients treated with stem cells obtained fr...
What are the most important risk factors for a patient's developing intraoperative hypothermia?
Anesthesiologists attempt to maintain perioperative normothermia for surgical patients. We surveyed clinical anesthesiologists and physician researchers and asked them to prioritize risk factors for a patient to develop intraoperative hypothermia. The questionnaire included 41 factors associated with changes in patient...
Return to an athletic lifestyle after osteochondral allograft transplantation of the knee
BACKGROUND: Osteochondral allograft transplantation (OATS) is a treatment option that provides the ability to restore large areas of hyaline cartilage anatomy and structure without donor site morbidity and promising results have been reported in returning patients to some previous activities. However, no study has repo...
Reconstruction of composite leg defects post-war injury
BACKGROUND: In a high conflict region, war injuries to the distal lower extremity are a major source of large composite defects involving bone and soft tissues. These defects are at the edge between using a single free flap [osteo-(+/-myo) cutaneous] vs double free flap reconstruction (bone and soft tissue). In this pa...
The use of benzodiazepines in the aged patient: Clinical and pharmacological considerations
Benzodiazepines are widely used to treat anxiety and insomnia in elderly patients. The interest of this prescription is discussed in this article. The discussion is based on the pharmacological properties and adverse effects of benzodiazepines in the elderly subjects. The conclusions are that benzodiazepines should be ...
Prevalence and risk factors for non-vertebral fractures in patients receiving oral glucocorticoids
Introduction: Glucocorticoids taken orally increase the risk of fractures. It has been noted that a dose as low as 2.5 mg/day increases the risk of vertebral fracture. What is less clear is the possible influence of other risk factors for osteoporosis on the presence of non-vertebral fractures in patients taking glucoc...
The effect of calcitriol on endoplasmic reticulum stress response
Calcitriol, the active form of vitamin D, is known for its anticancer properties including induction of apoptosis, inhibition of angiogenesis, and metastasis. Calcitriol also increases intracellular calcium triggering apoptosis in a calpain-dependent manner. Since the main storage unit for cellular calcium is endoplasm...
Circumferential abdominoplasty for sequential treatment after morbid obesity
BACKGROUND: The severely obese patient, after considerable loss of weight, has large remaining skin folds. Classic transverse abdominoplasties leave bulges in the flanks. This article presents an alternative procedure, circumferential abdominoplasty, which involves the perimeter of the abdomen. METHODS: Average age of ...
Healing rate of transverse osteotomies of the olecranon used in reconstruction of distal humerus fractures
To determine the rate of healing of the osteotomy, we studied the cases of 10 patients who had transverse osteotomy of the olecranon for surgical exposure of a complex distal humerus fracture. The average age of the patients was 48 years, and the average follow-up was 24 months. Nine of the fractures were complex supra...
Autologous Chondrocyte Implantation Improves Knee-Specific Functional Outcomes and Health-Related Quality of Life in Adolescent Patients
BACKGROUND: Existing studies of autologous chondrocyte implantation (ACI) in adolescent patients have primarily reported outcomes that have not been validated for cartilage repair and have failed to include measures of general health or health-related quality of life. PURPOSE: This study assesses validated knee-specifi...
T-condylar fractures of the distal humerus in children: report on three cases
T-condylar fractures of the distal humerus are very rare in children. Because of their rarity, there is a lack of evidence in the literature on the best method to treat such fractures. We report the cases of three paediatric patients with T-condylar fracture of the distal humerus. A high degree of attention is needed i...
Increased serum and synovial levels of midkine are associated with radiological progression in primary knee osteoarthritis patients
Background: Midkine is a heparin-binding growth factor that is believed to have functional antagonism, although it helps in tissue repair, it can also enhance inflammatory reactions resulting in more tissue injury. Aim of the work: This study aimed to determine serum and synovial fluid (SF) levels of midkine in patient...
Dry Arthroscopy of the Wrist: Surgical Technique
Purpose: To present a method to perform arthroscopic exploration and instrumentation without infusing any fluid. Methods: The hand is suspended from a bow, with traction on all fingers. Portals are developed as in the classic (wet) wrist arthroscopic procedure except that no water is infused to distend the joint and cr...
Long-term trends in the incidence of distal forearm fractures
In this population-based descriptive study covering the 50-year period, 1945-94, there was a statistically significant increase in distal forearm fractures due to severe trauma in both women and men (p < 0.001) but no secular increase in fractures due to moderate trauma (approximately osteoporosis). Since fractures att...
Novel quantitative assessment of metamorphopsia in maculopathy
PURPOSE: Patients with macular disease often report experiencing metamorphopsia (visual distortion). Although typically measured with Amsler charts, more quantitative assessments of perceived distortion are desirable to effectively monitor the presence, progression, and remediation of visual impairment. METHODS: Partic...
The relationship between external knee moments and muscle co-activation in subjects with medial knee osteoarthritis
PURPOSE: External knee moments are reliable to measure knee load but it does not take into account muscle activity. Considering that muscle co-activation increases compressive forces at the knee joint, identifying relationships between muscle co-activations and knee joint load would complement the investigation of the ...
Intra-articular fractures of the distal femur: a long-term follow-up study of surgically treated patients
OBJECTIVE: To analyze the long-term (5-25 years) functional and radiologic results of surgically treated intra-articular fractures of the distal femur. DESIGN: Retrospective study. SETTING: University hospital. PATIENTS AND METHODS: Sixty-seven surgically treated consecutive patients with 67 intra-articular distal femo...
What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients
BACKGROUND: Total hip or knee replacement is highly successful when judged by prosthesis-related outcomes. However, some people experience long-term pain. OBJECTIVES: To review published studies in representative populations with total hip or knee replacement for the treatment of osteoarthritis reporting proportions of...
Prophylaxis of Infective Endocarditis: Prevention of the Perfect Storm
Despite the availability of endocarditis prophylaxis guidelines for more than five decades, no prospective, randomised trial has ever been conducted to evaluate the efficacy and safety of this practice. This fact, in combination with mixed results from case-control investigations and other factors, has prompted a re-ev...
Does the timing of reoperation influence the risk of graft infection?
OBJECTIVE: This study compared the incidence and characteristics of graft infection in patients who underwent early vs late revisional surgery of lower extremity arterial bypass grafts. METHODS: Between 1992 and July 2005, 500 revisional procedures were performed on 198 lower extremity bypass grafts. Patients whose rev...
Randomized phase III trial of bleomycin, vindesine, mitomycin-C, and cisplatin (BEMP) versus cisplatin (P) in disseminated squamous-cell carcinoma of the uterine cervix: an EORTC Gynecological Cancer Cooperative Group study
PURPOSE: Three previous mitomycin-cisplatin-based chemotherapy trials conducted within the EORTC Gynecological Cancer Cooperative Group (GCCG) in patients with disseminated squamous-cell carcinoma of the uterine cervix (SCCUC) suggested that with such regimens a higher overall response rate and a higher complete respon...
Medial compartment knee replacement-a Caribbean perspective
Objective: To show the feasibility of medial compartment knee replacement (MCKR) in the Caribbean population. Design and Methods: Four patients ages 41-59 years received MCKR based on a presentation of medial compartment osteoarthritis. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and ra...
Predictive values of calcaneal quantitative ultrasound and dual energy X ray absorptiometry for non-vertebral fracture in older men: results from the MrOS study (Hong Kong)
Calcaneal QUS is comparable to DXA in predicting non-vertebral fractures in older Chinese men. INTRODUCTION: The predictive values of calcaneal quantitative ultrasound (QUS) and dual-energy X-ray absorptiometry (DXA) for non-vertebral fractures in older Chinese men were examined. METHODS: One thousand nine hundred twen...
Recurrent Desmoid Tumor with Intra-Abdominal Extension After Abdominoplasty: A Rare Presentation
BACKGROUND Desmoid tumors are fibrous neoplasms that originate from the musculoaponeurotic structures in the body. Abdominal wall desmoid tumors are rare, but they can be locally aggressive, with high incidence of recurrence. These tumors are more common in young, fertile women. They frequently occur during or after pr...
Medical care of elderly patients with hip fractures
Medical morbidity associated with hip fractures in the elderly population is considerable. The all-cause mortality rate is 24% at 12 months. The functional limitations of survivors can be pronounced. As the American population ages, hip fractures will substantially affect the utilization of hospital resources. Several ...
Clinical phenotype and musculoskeletal characteristics of patients with aggrecan deficiency
Aggrecan is a proteoglycan within the physeal and articular cartilage. Aggrecan deficiency, due to heterozygous mutations in the ACAN gene, causes dominantly inherited short stature and, in many patients, early-onset osteoarthritis and degenerative disc disease. We aimed to further characterize this phenotypic spectrum...
Effects of local anesthesia with bupivacaine plus epinephrine on blepharoptosis and levator palpebrae muscle function
PURPOSE: To evaluate the effect of local anesthesia with bupivacaine plus epinephrine on the extent of blepharoptosis and levator palpebrae muscle function. METHODS: : In this prospective interventional case series, patients with blepharoptosis who were candidates for aponeurotic surgery were included. After initial pr...
Foot pressure pattern, hindfoot deformities, and their associations with foot pain in individuals with advanced medial knee osteoarthritis
This survey clarified foot pressure patterns and hindfoot deformities in individuals with advanced knee osteoarthritis (OA) and analyzed their associations with foot pain. Sixty-four individuals with unilateral knee OA who underwent total knee arthroplasty (TKA) were divided into the following groups: no foot pain (n=2...
High-risk chief complaints III: abdomen and extremities
Abdominal and extremity complaints are a frequent reason for presentation to the emergency department. Although these are common complaints, several abdominal and extremity disease entities may be missed or may be subject to delayed diagnosis. This article provides an overview of the diagnosis and management of several...
Regenerative treatment of osteochondral lesions of distal tibial plafond
OBJECTIVES: Osteochondral lesions of the distal tibial plafond (OLTP) are rare and far less common than osteochondral lesions of the talus. Literature data do not report clinical records with significant number of cases and follow-up. The aim of our study was to evaluate clinical and MRI outcomes following arthroscopic...
Rothia aeria as a cause of sepsis in a native joint
Rothia aeria is a recently described Gram-positive rod from the family Micrococcaceae. An elderly woman with rheumatoid arthritis and dental abscesses who was undergoing immunosuppression had R. aeria isolated from synovial fluid. This report characterizes this rare organism and contributes to the literature on its pat...
Patient selection for skin-tightening procedures
Noninvasive skin-tightening devices have become increasingly popular over the last decade to improve skin laxity with minimal risk and recovery time. Proper patient selection improves patient outcomes and satisfaction. There are many devices available for tightening including monopolar radiofrequency, bipolar radiofreq...
Management of odontoid fractures in the elderly
Odontoid fractures are frequent in patients over 70 years of age, and in patients over 80 years of age they form the majority of spinal fractures. In a retrospective analysis of 23 geriatric (> 70 years) patients with a fracture of the odontoid, we compared some of the clinical features to a contemporary series of pati...
Preoperative methylprednisolone increases plasma Pentraxin 3 early after total knee arthroplasty: a randomized, double-blind, placebo-controlled trial
Preoperative glucocorticoid administration reduces the systemic inflammatory response. Pentraxin 3 (PTX3) is a novel inflammatory marker belonging to the humoral arm of innate immunity exerting a potentially protective host response. This study evaluated PTX3 and other complement marker changes after preoperative methy...
Moderators of Effects of Internet-Delivered Exercise and Pain Coping Skills Training for People With Knee Osteoarthritis: Exploratory Analysis of the IMPACT Randomized Controlled Trial
BACKGROUND: Internet-delivered exercise, education, and pain coping skills training is effective for people with knee osteoarthritis, yet it is not clear whether this treatment is better suited to particular subgroups of patients. OBJECTIVE: The aim was to explore demographic and clinical moderators of the effect of an...
The use of the McKeever metallic hemiarthroplasy for unicompartmental arthritis
We reviewed the results of sixty-one McKeever unicompartmental arthroplasties performed by the senior one of us (T. P.) for osteoarthritis of the knee. The average follow-up was five years (range, two to thirteen years). Forty-four (72 per cent) of the arthroplasties were rated as good to excellent. The average postope...
Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results
INTRODUCTION: Second-generation autologous chondrocyte implantation with scaffolds stabilizing the grafts is a clinically effective procedure for cartilage repair. In this ongoing prospective observational case report study, we evaluated the effectiveness of BioSeed-C, a cell-based cartilage graft based on autologous c...
CSF circulation in subjects with the empty sella syndrome
The etiology to the empty sella syndrome (ESS) is not known. Increased intracranial pressure (ICP) has been suggested to be one of the possible causes. In the present study the CSF circulation was analyzed in 48 subjects with ESS with gamma cisternography, pneumoencephalography (PEG) and computed tomography (CT). In 80...
Differences in gait pattern parameters between medial and anterior knee pain in patients with osteoarthritis of the knee
BACKGROUND: Patients with osteoarthritis of the knee have unique spatiotemporal gait alterations. These gait changes have not yet been differentiated according to the location of knee pain. The purpose of this study was to compare the gait patterns of patients with symptomatic knee osteoarthritis that exhibit either an...
Change in brow position after upper blepharoplasty or levator advancement
Brow position after blepharoplasty is somewhat controversial. Some authors insist that brow position remains unchanged after surgery. On the other hand, there is also an opinion that brow position changes after surgery.We evaluate the influence of upper blepharoplasty or correction of ptosis on brow position in East As...
The epidemiology of osteosarcoma
Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common primary bone malignancy. The incidence rates and 95% confidence intervals of osteosarcoma for all races and both sexes are 4.0 (3.5-4.6) for the range 0-14 years and 5.0 (4.6-5.6) for the range 0-19 years per year per million pers...
Bone mineral density at the hip in Norwegian women and men--prevalence of osteoporosis depends on chosen references: the Tromso Study
This study describes bone mineral density (BMD) and the prevalence of osteoporosis in women and men between 30-89 years in an unselected population. BMD was measured in g/cm(2) at total hip and femoral neck by dual-energy-X-ray absorptiometry in 3,094 women and 2,132 men in the 2001 Tromso Study. BMD levels were signif...
A constrained liner cemented into a secure cementless acetabular shell
BACKGROUND: Constrained acetabular components have been used to treat hips with recurrent instability following total hip arthroplasty and hips that demonstrate instability during revision surgery. In such hips, when a secure cementless acetabular shell is present, the surgeon can cement a constrained liner into the ex...
Elective implant removal in symptomatic patients after internal fixation of proximal humerus fractures improves clinical outcome
Background: Operative treatment is the standard for severely displaced proximal humerus fractures, but functional impairment can persist. Retaining of the implant can be a reason and in other fracture situations has proved to ameliorate patient satisfaction. The aim of this study was to analyse the functional outcome a...
Quadriceps strength and the time course of functional recovery after total knee arthroplasty
STUDY DESIGN: Prospective study with repeated measures. OBJECTIVES: The overall goal of this investigation was to describe the time course of recovery of impairments and function after total knee arthroplasty (TKA), as well as to provide direction for rehabilitation efforts. We hypothesized that quadriceps strength wou...
A randomized, controlled multicenter study evaluating focused ultrasound treatment for fat reduction in the flanks
Introduction: Energy-based cosmetic devices offer an in-office treatment option, with minimal downtime, to non-invasively remove unwanted fat. We evaluated focused, pulsed ultrasound treatment to randomized flanks, compared to corresponding non-treated contralateral flanks. Material and Methods: Subjects were enrolled ...
Anterior knee pain in the young athlete: diagnosis and treatment
The underlying etiology of anterior knee pain has been extensively studied. Despite many possible causes, often times the diagnosis is elusive. The most common causes in the young athlete are osteosynchondroses, patellar peritendinitis and tendinosis, synovial impingement, malalignment, and patellar instability. Less c...
Repeat liposuction-curettage treatment of axillary hyperhidrosis is safe and effective
BACKGROUND: Liposuction-curettage (LC) is an effective surgical therapy option for axillary hyperhidrosis, with less scarring compared with radical excision of axillary skin. Although this method has proven to be effective, the treatment of nonresponders to minimally invasive surgery has not been previously defined. Wh...