id stringlengths 1 3 | document_id stringlengths 11 13 | passages list | entities list | events list | coreferences list | relations list |
|---|---|---|---|---|---|---|
0 | PMID-12484699 | [
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"Regulation of transforming growth factor-beta signaling and vascular diseases.\n\nPURPOSE: Members of the transforming growth factor (TGF)-beta superfamily play critical roles in regulation of various cellular functions. Dysregulation o... | [
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1 | PMID-16268479 | [
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"Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt.\n\nDomain 5 (D5) of cleaved high molecular weight kininogen (HKa) inhibits angiogenesis in vivo and endothelial cell migration in vitro... | [
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2 | PMID-11121230 | [
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"RNA damage and inhibition of neoplastic endothelial cell growth: effects of human and amphibian ribonucleases.\n\nAngiogenesis defines the many steps involved in the growth and migration of endothelial cell-derived blood vessels. This p... | [
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3 | PMID-12610665 | [
{
"id": "PMID-12610665__text",
"type": "abstract",
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"Arteriogenesis: the development and growth of collateral arteries.\n\nIn patients with atherosclerotic vascular diseases, collateral vessels bypassing major arterial obstructions have frequently been observed. This may explain why some ... | [
{
"id": "PMID-12610665_T2",
"type": "Multi-tissue_structure",
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"id": "PMID-12610665_T3",
"type": "Multi-tissue_structure",
"text": [
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"ref_id": "PMID-12610665_T11"
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... | [] | [] |
4 | PMID-17462601 | [
{
"id": "PMID-17462601__text",
"type": "abstract",
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"An antibody directed against PDGF receptor beta enhances the antitumor and the anti-angiogenic activities of an anti-VEGF receptor 2 antibody.\n\nPlatelet-derived growth factor (PDGF) and its receptors (PDGFR) play important roles in tu... | [
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"type": "Gene_or_gene_product",
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... | [
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5 | PMID-19369582 | [
{
"id": "PMID-19369582__text",
"type": "abstract",
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"Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.\n\nAngiogenesis is a fundamental process to normal and abnormal tissue growth and repair, whi... | [
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... | [] |
6 | PMID-10589785 | [
{
"id": "PMID-10589785__text",
"type": "abstract",
"text": [
"The antiangiogenic agent linomide inhibits the growth rate of von Hippel-Lindau paraganglioma xenografts to mice.\n\nThe aim of this study was to ascertain the potential usefulness of the antiangiogenic compound linomide for treatment o... | [
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"role": "Theme",
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... | [] | [] |
7 | PMID-12140030 | [
{
"id": "PMID-12140030__text",
"type": "abstract",
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"Optimizing treatment of choroidal neovascularization feeder vessels associated with age-related macular degeneration.\n\nPURPOSE: To optimize the method of treating choroidal neovascularization (CNV) associated with age-related macular ... | [
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... | [
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8 | PMID-11238633 | [
{
"id": "PMID-11238633__text",
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"IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk.\n\nIn vivo IL-12-dependent tumor inhibition rests on the ability of IL-12 to activate a CD8-mediated cytotoxicity, inhibi... | [
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[
... | [
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9 | PMID-16310808 | [
{
"id": "PMID-16310808__text",
"type": "abstract",
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"Effect of thalidomide affecting VEGF secretion, cell migration, adhesion and capillary tube formation of human endothelial EA.hy 926 cells.\n\nAngiogenesis, new blood vessel formation, is a multistep process, precisely regulated by pro-... | [
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"VEGF"
],
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... | [
{
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"arguments": [
{
"role": "Theme",
"ref_id": "PMID-16310808_T4"
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... | [
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10 | PMID-15725689 | [
{
"id": "PMID-15725689__text",
"type": "abstract",
"text": [
"Role of thrombogenic factors in the development of atherosclerosis.\n\nHemostatic factors play a crucial role in generating thrombotic plugs at sites of vascular damage (atherothrombosis). However, whether hemostatic factors contribute ... | [
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"text": [
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"role": "Cause",
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... | [
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11 | PMID-10771470 | [
{
"id": "PMID-10771470__text",
"type": "abstract",
"text": [
"Active hair growth (anagen) is associated with angiogenesis.\n\nAfter the completion of skin development, angiogenesis, i.e., the growth of new capillaries from pre-existing blood vessels, is held to occur in the skin only under patholo... | [
{
"id": "PMID-10771470_T2",
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"id": "PMID-10771470_T3",
"type": "Tissue",
"text": [
"capillaries"
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[
... | [
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"arguments": [
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{
"id": ... | [] | [] |
12 | PMID-18835936 | [
{
"id": "PMID-18835936__text",
"type": "abstract",
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"Angiogenesis associated with visceral and subcutaneous adipose tissue in severe human obesity.\n\nOBJECTIVE: The expansion of adipose tissue is linked to the development of its vasculature. However, the regulation of adipose tissue angi... | [
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"id": "PMID-18835936_T3",
"type": "Tissue",
"text": [
"subcutaneous adipose tissue"
],
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... | [
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"id": "PMID-18835936_E1",
"type": "Development",
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"text": [
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"arguments": [
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"role": "Theme",
"ref_id": "PMID-18835936_T4"
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... | [
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}
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13 | PMID-12823209 | [
{
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"type": "abstract",
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"Prognostic value of p53 protein expression and vascular endothelial growth factor expression in resected squamous cell carcinoma of the esophagus.\n\nThe most common genetic alterations found in a wide variety of cancers are p53 tumor s... | [
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14 | PMID-10487573 | [
{
"id": "PMID-10487573__text",
"type": "abstract",
"text": [
"External beam radiotherapy for subretinal neovascularization in age-related macular degeneration: is this treatment efficient?\n\nPURPOSE: Control of the natural course of subretinal neovascularization (SRNV) in age-related macular dege... | [
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"macular"
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222,
... | [
{
"id": "PMID-10487573_E3",
"type": "Breakdown",
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"arguments": [
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"role": "Theme",
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... | [] | [] |
15 | PMID-10978899 | [
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"text": [
"Urokinase receptor: a molecular organizer in cellular communication.\n\nIn a variety of cell types, the glycolipid-anchored urokinase receptor (uPAR) is colocalized pericellularly with components of the plasminogen activation system and... | [
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"type": "Gene_or_gene_product",
"text": [
"glycolipid-anchored u... | [
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"type": "Gene_expression",
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... | [
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16 | PMID-16398404 | [
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"The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.\n\np63, a p53 homologue, is a myoe... | [
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"type": "Gene_or_gene_product",
"text": [
"vascul... | [
{
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"type": "Regulation",
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"arguments": [
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... | [
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... | [] |
17 | PMID-19236257 | [
{
"id": "PMID-19236257__text",
"type": "abstract",
"text": [
"Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors.\n\nBACKGROUND: Aberrant angiogenesis is a landmark feature in cancer, which is important for proliferation, growth... | [
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},
{
"id": "PMID-19236257_T2",
"type": "Drug_or_compound",
"text": [
"AVE0005"
],
"offsets": [
... | [
{
"id": "PMID-19236257_E14",
"type": "Negative_regulation",
"trigger": {
"text": [
"inhibit"
],
"offsets": [
[
489,
496
]
]
},
"arguments": [
{
"role": "Theme",
"ref_id": "PMID-19236257_E15"
},
... | [
{
"id": "PMID-19236257_1",
"entity_ids": [
"PMID-19236257_T1",
"PMID-19236257_T2"
]
}
] | [
{
"id": "PMID-19236257_R1",
"type": "frag",
"arg1_id": "PMID-19236257_T19",
"arg2_id": "PMID-19236257_T20",
"normalized": []
}
] |
End of preview. Expand
in Data Studio
Dataset Card for MLEE
MLEE is an event extraction corpus consisting of manually annotated abstracts of papers on angiogenesis. It contains annotations for entities, relations, events and coreferences The annotations span molecular, cellular, tissue, and organ-level processes.
Citation Information
@article{pyysalo2012event,
title={Event extraction across multiple levels of biological organization},
author={Pyysalo, Sampo and Ohta, Tomoko and Miwa, Makoto and Cho, Han-Cheol and Tsujii, Jun'ichi and Ananiadou, Sophia},
journal={Bioinformatics},
volume={28},
number={18},
pages={i575--i581},
year={2012},
publisher={Oxford University Press}
}
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