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10,005,400 | Growth rates of Actinomyces viscosus and Streptococcus mutans during early colonization of tooth surfaces in gnotobiotic rats. | [
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10,005,401 | Germfree Osborne-Mendel rats were monoassociated with Actinomyces viscosus or Streptococcus mutans. The adherence and subsequent growth of these organisms on the tooth surface was studied by means of total viable cell counts. Both A. viscosus and S. mutans showed a lag phase and an exponential growth phase, similar to ... | [
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10,005,402 | Serum resistance associated with virulence in Yersinia enterocolitica. | [
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10,005,403 | Yersinia enterocolitica strains that exhibited a calcium requirement for growth and autoagglutination at 37 degrees C were invariably virulent in rabbits, causing diarrhea and a high degree of lethality, and were capable of colonizing the intestinal lumen and establishing foci of infection on the Peyer's patches of mic... | [
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10,005,404 | Contractile effects of bacterial cell walls, their enzymatic digests, and muramyl dipeptides on ileal strips from guinea pigs. | [
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10,005,405 | Cell walls isolated from four bacterial species (Streptococcus pyogenes, Lactobacillus plantarum, Streptomyces gardneri, and Nocardia corynebacteriodes), which exhibited the adjuvant effect of stimulating cellular and humoral immune responses against ovalbumin in guinea pigs, caused the slow-starting and long-lasting c... | [
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10,005,406 | Plasmid pattern analysis of Staphylococcal epidermidis isolates from patients with prosthetic valve endocarditis. | [
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10,005,407 | The electrophoretic pattern formed by individual bacterial plasmid DNA molecules of differing molecular size was evaluated as an epidemiological marker among isolates of Staphylococcus epidermidis from patients with prosthetic valve endocarditis (PVE). Purified covalently closed circular plasmid DNA was obtained from s... | [
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10,005,408 | Enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides: prevalence among individuals with and without diarrhea in Thailand. | [
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10,005,409 | To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers ... | [
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10,005,410 | Effects of corticosteroids and cyclophosphamide on a mouse model of Chlamydia trachomatis pneumonitis. | [
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10,005,411 | Suppression of the inflammatory reaction with daily doses of cortisone acetate or cyclophosphamide substantially prolonged the pulmonary infection in mice which had been intranasally inoculated with a trachoma biotype of Chlamydia trachomatis. Titration of organisms recovered from the lungs of treated mice revealed a d... | [
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10,005,412 | Effect of hydrocortisone on macrophage response to lymphokine. | [
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10,005,413 | To define the suppressive effects of corticosteroids on mononuclear phagocyte antiprotozoal activity, normal resident peritoneal macrophages were exposed to hydrocortisone (HC) before, during, and after in vitro activation with cell-free supernatants (lymphokines). The presence of pharmacological concentrations of HC b... | [
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10,005,414 | Localization of Mycoplasma pulmonis in cartilage. | [
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10,005,415 | Transmission electron microscopy of articular cartilage in Mycoplasma pulmonis-infected neonatal rats revealed the presence of mycoplasmas within the matrix and lacunae. The mycoplasmas appeared to have a tropism for the chondrocytes and induced lysis of both the chondrocytes and matrix of the cartilage. | [
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10,005,416 | Relationship between cell wall synthesis in Propionibacterium acnes and ability to stimulate the reticuloendothelial system. | [
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10,005,417 | The addition of chloramphenicol or tetracycline to exponentially growing cells of Propionibacterium acnes, which are not normally able to induce splenomegaly until they reach stationary phase, resulted in a rapid development of ability to induce splenomegaly in mice. However, the activity resulting from chloramphenicol... | [
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10,005,418 | Non-immunoglobulin fraction of human milk protects rabbits against enterotoxin-induced intestinal fluid secretion. | [
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10,005,419 | Human milk was fractionated by ammonium sulphate precipitation and column chromatography. A milk fraction depleted of secretory immunoglobulin A and with an apparent molecular weight of greater than 400,000 inhibited fluid secretion induced by cholera toxin and Escherichia coli heat-labile toxin in rabbit ileal loops. | [
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10,005,420 | Specificity of natural antibodies reactive with Streptococcus mutans in monkeys. | [
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10,005,421 | Enzyme-linked immunosorbent assays were used to measure levels of natural antibody to defined antigens of Streptococcus mutans in sera from monkeys (Macaca fascicularis). The results suggest that most of the antibody in young monkeys that binds to whole bacteria is not specific to S. mutans. | [
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10,005,422 | Salmonella toxin synthesis is unrelated to the presence of temperate bacteriophages. | [
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10,005,423 | Several strains of Salmonella were examined for an association between the capacity to produce Salmonella toxin and the presence of bacteriophages. Based on the data obtained from this study, we concluded that genetic information responsible for Salmonella toxin synthesis was not inherited by lysogenic conversion. | [
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10,005,424 | Comparative studies on tree pollen allergens. II. Isolation of alder (Alnus incana) pollen allergens: purification and some characteristics of the major allergen pI 4.78. | [
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10,005,425 | The aqueous extract of alder (Alnus incana) pollen was found to consist of a protein mixture amounting to 3% of the dry pollen weight. Separation by gel permeation chromatography on an AcA-54 column resulted in 6 fractions designated chronologically to their relative elution volumes (AI 1 to AI 6). The immunological re... | [
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10,005,426 | Increased levels of IgG4 subclass in 5 patients with acquired respiratory disease. | [
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10,005,427 | 5 sera from a series of more than 1,000 serum samples from hospitalized patients tested by immunoelectrophoresis were selected for further examination because of a disproportional increase in the anodic part of IgG. A marked polyclonal increase in IgG4 subclass level was detected in each of these sera. While the patien... | [
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10,005,428 | Preferential induction of cell-mediated immunity by chemically modified carcinoembryonic antigen. | [
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10,005,429 | Modification of carcinoembryonic antigen (CEA) with various chemicals was investigated. Modification of CEA with dimethylsulfate or acetic anhydride resulted in derivatives which preferentially induced delayed-type hypersensitivity (DTH) against native CEA in mice. The strength of the DTH reaction was dependent on the ... | [
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10,005,430 | Serologically defined antigens on the surface of somatic hybrid cells. | [
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10,005,431 | Y2C somatic cell hybrids, which immunize semiallogeneic mice and protect them against further challenge with syngeneic malignant cells, express normal H-2 antigens from parental cells and, in addition, the L antigen and the Friend, Moloney, Rauscher type-specific antigen. This was demonstrated by immunoabsorption, comp... | [
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10,005,432 | Enhanced cellular immune response to type I collagen in patients with periodontal disease. | [
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10,005,433 | Lymphoblastic responses to native denatured homologous type I collagen were significantly greater in 28 patients with chronic periodontal disease than in the control group of 28 subjects matched for age and sex. In the disease group, the lymphoblastic responses tended to increase with increasing severity of the disease... | [
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10,005,434 | Regulation of natural killer activity in vivo. III. Effect of hypophysectomy and growth hormone treatment on the natural killer activity of the mouse spleen cell population. | [
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10,005,435 | Spleen natural killer (NK) activity against YAC tumor cells was reduced in female C57BL/6J mice hypophysectomized at 3 weeks and sacrificed 4-8 weeks later. Proportions of null cells and of target binding cells in spleens from hypophysectomized and sham operated mice were significantly different. Administration of ovin... | [
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10,005,436 | Development of beryllium lymphocyte transformation tests in chronic beryllium disease. | [
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10,005,437 | We found that optimal conditions for the beryllium transformation test required the use of purified lymphocyte suspensions in 20% human serum, with beryllium sulphate at concentrations of 10(-6) to 10(-7) M. Using these conditions, all 15 chronic beryllium patients tested gave a stimulation index of more than 2. Despit... | [
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10,005,438 | Effects of levamisole and D-penicillamine on contact sensitivity to oxazolone in rats. | [
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10,005,439 | Levamisole, but not D-penicillamine, inhibited the oxazolone delayed hypersensitivity in rats. It was more effective when given locally to the ear (the tissue being challenged with oxazolone) or when injected intraperitoneally 24 h previously. Rats bred for resistance to the dextran anaphylactoid reaction exhibit conta... | [
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10,005,440 | Potentiated reagin response to ovalbumin in Schistosoma mansoni infected rats and in rats treated with a soluble metabolic product from adult worms. | [
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10,005,441 | Infection by Schistosoma mansoni in the rat was found able to maintain high levels of reaginic antibody to an unrelated antigen, ovalbumin, mainly when infection was carried out 14 days after immunization. In addition, administration of a soluble metabolic product of living worms, the immunosuppressive activity of whic... | [
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10,005,442 | Re-establishment of traumatically disrupted finger flexor function: a brief communication. | [
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10,005,443 | IgE and haemagglutinating antibody production in mice following intranasal immunization with ryegrass pollen. | [
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10,005,444 | Repeated intranasal immunization of mice whole ryegrass pollen (RGP) led to the development of high circulating titres of both IgE and haemagglutinating antibodies. Bordetella pertussis vaccine (BPV) was required at the time of initial immunization, although its repeated use did not affect IgE production. Antibody prod... | [
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10,005,445 | Effects of ethnicity of hypnotist and subject on hypnotic susceptibility. | [
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10,005,446 | Visual information processing in high and low susceptible subjects. | [
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10,005,447 | Individual differences in hypnotizability and effectiveness of hypnosis or biofeedback. | [
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10,005,448 | Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part II - Small molecular weight immunomodulators produced by microorganisms. | [
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10,005,449 | A screening method to identify microbial products that bind to surfaces of cells involved in immunity has been established. By means of this method, several small molecular weight compounds, bestatin, amastatin, forphenicine, and esterastin, inhibiting enzymes located on the cell surface, aminopeptidase B and leucine a... | [
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10,005,450 | 1-deamino-/4-valine-8-D-arginine/-vasopressin (dVDAVP), a new synthetic vasopressin analog for treating diabetes insipidus. | [
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10,005,451 | The effects of LVP, dDAVP, and dVDAVP on the water excretion of 14 vasopressin-sensitive and 2 ADH-resistant patients with diabetes insipidus were studied and compared. Findings showed that dDAVP and dVDAVP decreased the diuresis of all ADH-sensitive patients, and in those with diabetes insipidus, more markedly (7.6-fo... | [
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10,005,452 | The effect of prednisone and azathioprine (Imuran) on renal excretion of uric acid. | [
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10,005,453 | Our study was conducted in two groups of subjects with normal renal function and with normal metabolism of uric acid. Findings showed that the administration of prednisone (Group 1) results in increased renal excretion of uric acid. The observed significant increases in the renal clearance and fractional excretion of u... | [
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10,005,454 | Effect of cimetidine on the absorption and efficacy of orally administered furosemide. | [
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10,005,455 | In six normal subjects who received single oral doses of 400 mg cimetidine and 40 mg furosemide, the area under the furosemide plasma concentration-time curve was increased in two subjects by less than 50%, in two by 59% and 75%, and remained unchanged in two: overall the mean increase of approximately one-third achiev... | [
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10,005,456 | Birthdate as a predictor for seeking admission to a drug treatment program. | [
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10,005,457 | Group interaction as a method of family therapy. | [
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10,005,458 | Technique in group psychotherapy of narcissistic and borderline patients. | [
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10,005,459 | Some key issues in the the group psychotherapy of narcissistic and borderline patients. | [
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10,005,460 | Some key issues in the group psychotherapy of narcissistic and borderline patients. Concluding remarks. | [
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10,005,461 | Therapeutic factors in group therapy with borderline patients. | [
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10,005,462 | Fighting parents' hopelessness. | [
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10,005,463 | Six types of borderline and narcissistic patients: an initial typology. | [
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10,005,464 | Impact of multiple-family therapy approach on a parallel latency-age/parent group. | [
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10,005,465 | Antagonistic effects of adrenalectomy and ether/surgical stress on light-induced photoreceptor damage. | [
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10,005,466 | Light-induced damage to retinal photoreceptors in influenced by the endocrine status of the animal during the period of exposure. Experimental manipulation of the pituitary gland and of prolactin levels has been shown to affect retinal damage in rats exposed to visible light. When rats are experimentally stressed, prol... | [
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10,005,467 | This pineal gland does not mediate phase shifts in the disc shedding rhythm of the rat retina. | [
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10,005,468 | Albino rats were subjected to pinealectomy, superior cervical ganglionectomy, or the appropriate sham preparation and were placed in lighting conditions so that light onset was advanced by 10 hr. After 6 days of this regimen, all animals exhibited a complete shift in their outer segment disc shedding rhythm, indicating... | [
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10,005,469 | Metastasis in a rabbit choroidal melanoma model. | [
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10,005,470 | A substrain of Greene hamster melanoma adapted to grow in the choroid of the rabbit eye is shown to have the tendency to metastasize. Twenty-one normal rabbits were studied for the effects of vascular inoculation of a tumor cell suspension prepared from this choroidal melanoma, and two rabbits were used for long-term o... | [
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10,005,471 | Tissue distribution of 3H-hematoporphyrin derivative in athymic "nude" mice heterotransplanted with human retinoblastoma. | [
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10,005,472 | Quantitative uptake levels of tritium-labeled hematoporphyrin derivative (3H-HpD) have been obtained for normal and malignant tissue of athymic "nude" mice heterotransplanted intraocularly with human retinoblastoma. It was determined that eyes with tumor accumulated higher levels of 3H-HpD than those in control eyes. I... | [
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10,005,473 | Reversal of anoxic corneal swelling by breathing oxygen. | [
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0.060182228684425354,
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0.054930638521909714,
0.07693056017160416,
0.020704304799437523,
-0.023968590423464775,
0.02... |
10,005,474 | Human eye tissue for research. | [
-0.01915420964360237,
-0.010875608772039413,
-0.018886350095272064,
-0.042294494807720184,
0.025751156732439995,
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0.08841951936483383,
0.03960476815700531,
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0.14672793447971344,
0.04863651841878891,
-0.008494725450873375,
-0.04946322366595268,
0.... |
10,005,475 | Spatial summation, contrast threshold, and aging. | [
0.1383616328239441,
-0.046175673604011536,
0.0743708461523056,
0.0028951833955943584,
-0.01142535638064146,
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0.04259788990020752,
0.02339094877243042,
0.00536975497379899,
0.004797804169356823,
0.027433695271611214,
0.0638379... |
10,005,476 | Concentration of 3H-8-methoxypsoralen and its metabolites in the rat lens and eye after a single oral administration. | [
0.0764385238289833,
-0.06503187865018845,
-0.019283156841993332,
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0.062010809779167175,
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0.01798839680850506,
0.00598466582596302,
-0.013863685540854931,
-0.0032924634870141745,
0... |
10,005,477 | Concentrations of 3H-8-methoxypsoralen (MOP), its lipid- and water-soluble metabolites, tritiated water, and an insoluble compound have been measured in rat serum, lens, and eye tissue by liquid scintillation, thin-layer chromatography, and other techniques. The radioactivity has been measured in albino and pigmented r... | [
0.06344762444496155,
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0.00019018635794054717,
0.005837305448949337,
0.014784338884055614,
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0.08851664513349533,
0.11908730119466782,
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-0.008616108447313309,
0.0023162721190601587,
-0.04441816732287407,
0.0017384516540914774,
... |
10,005,478 | The effect of lens depression on the components of outflow resistance. | [
-0.005940473638474941,
0.03477412834763527,
0.06932953000068665,
-0.013151990249752998,
0.030728740617632866,
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0.002677935641258955,
0.109843909740448,
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0.01959279179573059,
0.019312633201479912,
0.004166965372860432,
0.026025058701634407,
-0.01863... |
10,005,479 | The effect of lens depression on resistance to flow through the inner wall of Schlemm's canal, circumferentially along the canal, and through the collector channels was measured in enucleated eyes. In one series of experiments the anterior chamber was perfused while canal pressure was monitored, thus allowing us to est... | [
0.07600229233503342,
-0.03776054084300995,
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0.06857847422361374,
0.035907626152038574,
-0.06019146740436554,
0.01171434111893177,
0... |
10,005,480 | Schwalbe line's cells: a new cell type in the trabecular meshwork of Macaca mulatta. | [
-0.009233642369508743,
-0.06293118000030518,
-0.02029591239988804,
-0.031563594937324524,
-0.07754913717508316,
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0.03315521776676178,
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0.13603273034095764,
0.08502375334501266,
-0.07974442094564438,
-0.027895299717783928,
0.0... |
10,005,481 | In the eye of Macaca mulatta, at the anterior end of the trabecular meshwork, just beneath the ridge known as Schwalbe line in gonioscopy, cells are present that contain secretory inclusions. These cells have been termed Schwalbe line's cells. They form a discontinuous cord, oriented circumferentially at the corneal pe... | [
-0.07665617763996124,
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0.07671841979026794,
0.1042046770453453,
-0.09903120249509811,
-0.050212714821100235,
0.04765... |
10,005,482 | Isolation and characterization of fibronectin from bovine aqueous humor. | [
0.003986254334449768,
-0.11077859997749329,
-0.03495866805315018,
0.044797882437705994,
0.060646284371614456,
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0.054730501025915146,
0.07834316790103912,
0.05446885898709297,
0.04401081055402756,
0.025714319199323654,
-0.03164028748869896,
-0.05140033736824989,
0.0481... |
10,005,483 | Aqueous humor collected from freshly enucleated bovine eyes was passed over a gelatin affinity column, and bound material was eluted with 4M urea. When fractionated by sodium dodecyl sulfate electrophoresis, the eluted material co-migrated with human plasma fibronectin and protein standards of approximately 220,000 dal... | [
0.011575458571314812,
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0.00467135664075613,
0.031155463308095932,
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0.08714177459478378,
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0.06155161187052727,
0.0187052134424448,
-0.0494588278234005,
-0.032376840710639954,
0.063813... |
10,005,484 | Synaptic organization of the dopaminergic neurons in the retina of the cynomolgus monkey. | [
-0.022180752828717232,
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0.03967534005641937,
0.03780647739768028,
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0.03573134168982506,
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0.0591939240694046,
-0.031653519719839096,
-0.01596638932824135,
0.02588326297700405,
0.02770... |
10,005,485 | Dopaminergic neurons have previously been demonstrated in the retina of cynomolgus monkeys (Macaca fascicularis) by fluorescence microscopy. These neurons take up 5,6-dihydroxytryptamine, which alters their ultrastructure, and this technique has been used in the present study to identify the dopaminergic retinal neuron... | [
-0.03983341529965401,
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0.0005005468847230077,
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0.09579833596944809,
-0.02542888931930065,
-0.05084363371133804,
0.031179646030068398,
0.0281834... |
10,005,486 | Retinal localization of scotomata by scanning laser ophthalmoscopy. | [
0.0422557108104229,
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0.009141230024397373,
0.0667208582162857,
0.022297600284218788,
0.018344203010201454,
0.04877... |
10,005,487 | The scanning laser ophthalmoscope (SLO) system has been modified to permit direct retinal perimetry. A movable pinhole in a retinal conjugate plane furnishes a mapping stimulus whose retinal locus is directly observable on a video image of the fundus. Scotoma maps in patients with macular disease and physiologic scotom... | [
0.0939868688583374,
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0.006984020117670298,
0.06441108137369156,
0.0111564164981246,
0.014124797657132149,
0.0090... |
10,005,488 | Temporal contrast sensitivity in amblyopia. | [
0.13016188144683838,
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0.018194327130913734,
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-0.025701504200696945,
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-0.008514000102877617,
... |
10,005,489 | Temporal contrast sensitivity functions were determined for the normal (20/20) and amblyopic eyes of five strabismic and/or anisometropic amblyopes and for both eyes of two nonamblyopes. In deep amblyopia (20/100+), contrast sensitivity was reduced at all temporal frequencies in the amblyopic eye, whereas no deficit wa... | [
0.1436804085969925,
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0.0027492863591760397,
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0.003292088396847248,
-0.026411937549710274,
0.020506033673882484,
... |
10,005,490 | Distribution of melanosomes across the retinal pigment epithelium of a hooded rat: implications for light damage. | [
0.016401968896389008,
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0.0501004233956337,
0.11330635845661163,
0.02155868522822857,
0.0032656886614859104,
0.1179765835404396,
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0.06990360468626022,
-0.013211309909820557,
-0.07339927554130554,
-0.06154392287135124,
0.08692... |
10,005,491 | Distribution of melanosomes across the retinal pigment epithelium of hooded rats (Long-Evans) is studied at the light microscopic and electron microscopic levels. This distribution is shown to be nonuniform: more melanosomes exist in the periphery than elsewhere and, importantly, there are very few melanosomes in a res... | [
0.04818996042013168,
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0.06702766567468643,
0.10027521848678589,
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0.09816280007362366,
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0.07956000417470932,
-0.0007551998714916408,
-0.11384852230548859,
-0.0726953074336052,
0.0739... |
10,005,492 | The Stiles-Crawford effect in retinitis pigmentosa. | [
-0.04838006570935249,
-0.07322751730680466,
-0.027172138914465904,
0.08102697134017944,
-0.03282357379794121,
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0.02489308826625347,
0.06938111782073975,
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0.09265776723623276,
-0.03815837204456329,
0.005486266687512398,
0.008588379248976707,
0.043111... |
10,005,493 | Stiles-Crawford functions were obtained from the maculas of 22 patients with different genetic types of retinitis pigmentosa and visual acuity of 20/40 or better. Reduced cone directional sensitivity was seen in the fovea with both focal cone electroretinographic testing and psychophysical testing. Functions from the p... | [
-0.012257954105734825,
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0.06758563965559006,
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0.02928943559527397,
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0.0698147565126419,
0.04419168829917908,
-0.08199656009674072,
0.0003909704682882875,
0.03735... |
10,005,494 | Pathologic mechanisms of multifocal choroiditis with retinal detachment after carotid injection of Streptococcus mutans and other bacteria in dogs. | [
0.012888425029814243,
-0.1398356407880783,
0.05352970212697983,
0.08052970468997955,
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0.06567887961864471,
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0.03935253620147705,
0.04776756837964058,
-0.024896763265132904,
0.07482268661260605,
0.1466512... |
10,005,495 | Multifocal choroiditis with overlying retinal detachment occurs after carotid injection of certain bacteria in dogs. The ocular lesions occur mainly in the tapetal area of the retina, correlate with microabscesses in the inner choroid and subretinal space, and occasionally occur in the inner retina and anterior uveal t... | [
0.022091524675488472,
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0.06076139584183693,
0.007464451715350151,
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0.053020671010017395,
0.04976528510451317,
-0.017195578664541245,
0.05505281686782837,
0.181... |
10,005,496 | Phase separation of X-irradiated lenses of rabbit. | [
0.0439668633043766,
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0.023094044998288155,
0.0232546404004097,
0.05733868479728699,
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0.15475255250930786,
0.02821553312242031,
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0.09569471329450607,
0.12925761938095093,
0.02858847938477993,
0.03937948867678642,
0.0933421179652... |
10,005,497 | The phase separation temperature (Tcat) was studied as a function of time (age) after the administration of a single dose of radiation (2000 rad), which induces cataract in the rabbit lens. In the normal unirradiated lens, Tcat decreases linearly with age at a rate (DTcat/dt) approximately 2.2 degrees/week. In the irra... | [
0.06141892075538635,
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0.032897841185331345,
0.06001323461532593,
0.00318312831223011,
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0.06583638489246368,
0.025040432810783386,
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0.1040799468755722,
0.08830408751964569,
-0.024794291704893112,
0.03477059304714203,
0.04376325... |
10,005,498 | Liposomes in topical drug delivery. | [
0.023525109514594078,
-0.08293219655752182,
-0.043690457940101624,
0.02976016327738762,
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0.06994205713272095,
0.010107467882335186,
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-0.0006158119649626315,
0.017921803519129753,
0.04899540916085243,
-0.013252118602395058,
0.08... |
10,005,499 | The possible use of liposomes as topical drug delivery vehicles for both water- and lipid-soluble drugs has been investigated. Data for two characteristic drugs, penicillin G and indoxole, are presented. Liposome uptake by the cornea is greatest for positively charged liposomes, less for negatively charged liposomes, a... | [
0.03922991827130318,
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0.059923525899648666,
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0.05887441337108612,
0.06877490878105164,
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0.05467064306139946,
0.05878675356507301,
0.018853308632969856,
0.003229687921702862,
0.147... |
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