code
string
signature
string
docstring
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loss_without_docstring
float64
loss_with_docstring
float64
factor
float64
if isinstance(fileNameOrHandle, six.string_types): if fileNameOrHandle.endswith('.gz'): if six.PY3: yield gzip.open(fileNameOrHandle, mode='rt', encoding='UTF-8') else: yield gzip.GzipFile(fileNameOrHandle) elif fileNameOrHandle.endswith('...
def asHandle(fileNameOrHandle, mode='r')
Decorator for file opening that makes it easy to open compressed files. Based on L{Bio.File.as_handle}. @param fileNameOrHandle: Either a C{str} or a file handle. @return: A generator that can be turned into a context manager via L{contextlib.contextmanager}.
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result = set() for _range in s.split(','): match = _rangeRegex.match(_range) if match: start, end = match.groups() start = int(start) if end is None: end = start else: end = int(end) if start > end:...
def parseRangeString(s, convertToZeroBased=False)
Parse a range string of the form 1-5,12,100-200. @param s: A C{str} specifiying a set of numbers, given in the form of comma separated numeric ranges or individual indices. @param convertToZeroBased: If C{True} all indices will have one subtracted from them. @return: A C{set} of all C{int}s...
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result = [] for offset in sorted(nucleotides): result.append( '%s%d: %s' % (prefix, offset, baseCountsToStr(nucleotides[offset]))) return '\n'.join(result)
def nucleotidesToStr(nucleotides, prefix='')
Convert offsets and base counts to a string. @param nucleotides: A C{defaultdict(Counter)} instance, keyed by C{int} offset, with nucleotides keying the Counters. @param prefix: A C{str} to put at the start of each line. @return: A C{str} representation of the offsets and nucleotide counts ...
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def percentage(a, b): return 100.0 * a / b if b else 0.0 if count == 0: return '%s: %d' % (mesg, count) else: len2 = len2 or len1 if len1 == len2: return '%s: %d/%d (%.2f%%)' % ( mesg, count, len1, percentage(count, len1)) el...
def countPrint(mesg, count, len1, len2=None)
Format a message followed by an integer count and a percentage (or two, if the sequence lengths are unequal). @param mesg: a C{str} message. @param count: a numeric value. @param len1: the C{int} length of sequence 1. @param len2: the C{int} length of sequence 2. If C{None}, will default to...
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local_dir = os.path.join(genometools._root, 'data', 'gcloud', 'scripts') match = _BUCKET_PAT.match(script_dir) script_bucket = match.group(1) script_prefix = match.group(2) depth = len(local_dir.split(os.sep)) for root, dirs, files in os.walk(local_dir): rel_path = '/'.join(root.s...
def upload_scripts(client, script_dir, overwrite=True)
Uploads general-purpose scripts to a Google Storage bucket. TODO: docstring
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if filename.endswith('.json') or filename.endswith('.json.bz2'): return JSONRecordsReader(filename, scoreClass) else: raise ValueError( 'Unknown DIAMOND record file suffix for file %r.' % filename)
def _getReader(self, filename, scoreClass)
Obtain a JSON record reader for DIAMOND records. @param filename: The C{str} file name holding the JSON. @param scoreClass: A class to hold and compare scores (see scores.py).
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# Note that self._reader is already initialized (in __init__) for # the first input file. This is less clean than it could be, but it # makes testing easier, since open() is then only called once for # each input file. reads = iter(self.reads) first = True ...
def iter(self)
Extract DIAMOND records and yield C{ReadAlignments} instances. @return: A generator that yields C{ReadAlignments} instances.
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if self._subjectTitleToSubject is None: if self._databaseFilename is None: # An Sqlite3 database is used to look up subjects. self._subjectTitleToSubject = SqliteIndex( self._sqliteDatabaseFilename, fastaDirectory=self....
def getSubjectSequence(self, title)
Obtain information about a subject sequence given its title. @param title: A C{str} sequence title from a DIAMOND hit. @raise KeyError: If the C{title} is not present in the DIAMOND database. @return: An C{AAReadWithX} instance.
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urls = [] with ftputil.FTPHost(sra_host, sra_user, sra_password) as ftp_host: download_paths = [] exp_dir = '/sra/sra-instant/reads/ByStudy/sra/SRP/%s/%s/' \ %(project[:6], project) ftp_host.chdir(exp_dir) run_folders = ftp_host.listdir(ftp_host.curdir) ...
def get_project_urls(project)
Get the URLs for all runs from a given project. TODO: docstring
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''' Two's complement conversion of a binary number Input handshake & data rx_rdy - (o) Ready rx_vld - (i) Valid rx_dat - (i) Data Output handshake & data tx_rdy - (i) Ready tx_vld - (o) Valid tx_dat - (o) Data Implement...
def twos_complement(rst, clk, rx_rdy, rx_vld, rx_dat, tx_rdy, tx_vld, tx_dat)
Two's complement conversion of a binary number Input handshake & data rx_rdy - (o) Ready rx_vld - (i) Valid rx_dat - (i) Data Output handshake & data tx_rdy - (i) Ready tx_vld - (o) Valid tx_dat - (o) Data Implementation: 3...
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desc = 'Generate a mapping of Entrez IDs to gene symbols.' parser = cli.get_argument_parser(desc=desc) parser.add_argument( '-f', '--gene2acc-file', type=str, required=True, help=textwrap.dedent() ) parser.add_argument( '-o', '--output-file', type=str, required=True,...
def get_argument_parser()
Creates the argument parser for the extract_entrez2gene.py script. Returns ------- A fully configured `argparse.ArgumentParser` object. Notes ----- This function is used by the `sphinx-argparse` extension for sphinx.
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gene2acc = {} with misc.smart_open_read(file_path, mode='rb', try_gzip=True) as fh: reader = csv.reader(fh, dialect='excel-tab') next(reader) # skip header for i, l in enumerate(reader): id_ = int(l[1]) symbol = l[15] try: gene2a...
def read_gene2acc(file_path, logger)
Extracts Entrez ID -> gene symbol mapping from gene2accession.gz file. Parameters ---------- file_path: str The path of the gene2accession.gz file (or a filtered version thereof). The file may be gzip'ed. Returns ------- dict A mapping of Entrez IDs to gene symbols.
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with misc.smart_open_write(file_path, mode='wb') as ofh: writer = csv.writer(ofh, dialect='excel-tab', lineterminator=os.linesep) for k in sorted(entrez2gene.keys(), key=lambda x: int(x)): writer.writerow([k, entrez2gene[k]]) logger.info('Output writt...
def write_entrez2gene(file_path, entrez2gene, logger)
Writes Entrez ID -> gene symbol mapping to a tab-delimited text file. Parameters ---------- file_path: str The path of the output file. entrez2gene: dict The mapping of Entrez IDs to gene symbols. Returns ------- None
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vinfo = sys.version_info if not (vinfo >= (2, 7)): raise SystemError('Python interpreter version >= 2.7 required, ' 'found %d.%d instead.' % (vinfo.major, vinfo.minor)) if args is None: parser = get_argument_parser() args = parser.parse_args() gen...
def main(args=None)
Extracts Entrez ID -> gene symbol mapping and writes it to a text file. Parameters ---------- args: argparse.Namespace object, optional The argument values. If not specified, the values will be obtained by parsing the command line arguments using the `argparse` module. Returns ----...
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abbrev1 = None origS = s if ' ' in s: # Convert first word to title case, others to lower. first, rest = s.split(' ', 1) s = first.title() + ' ' + rest.lower() else: s = s.title() if s in NAMES: abbrev1 = s elif s in ABBREV3_TO_ABBREV1: abb...
def find(s)
Find an amino acid whose name or abbreviation is s. @param s: A C{str} amino acid specifier. This may be a full name, a 3-letter abbreviation or a 1-letter abbreviation. Case is ignored. return: An L{AminoAcid} instance or C{None} if no matching amino acid can be located.
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propertyNames = sorted(map(str.lower, set(propertyNames))) # Make sure all mentioned property names exist for at least one AA. knownProperties = set() for names in propertyValues.values(): knownProperties.update(names) unknown = set(propertyNames) - knownProperties if unknown: ...
def _propertiesOrClustersForSequence(sequence, propertyNames, propertyValues, missingAAValue)
Extract amino acid property values or cluster numbers for a sequence. @param sequence: An C{AARead} (or a subclass) instance. @param propertyNames: An iterable of C{str} property names (each of which must be a key of a key in the C{propertyValues} C{dict}). @param propertyValues: A C{dict} in the f...
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match = aaMatch['match'] matchCount = match['matchCount'] gapMismatchCount = match['gapMismatchCount'] gapGapMismatchCount = match['gapGapMismatchCount'] nonGapMismatchCount = match['nonGapMismatchCount'] if offsets: len1 = len2 = len(offsets) else: len1, len2 = map(len...
def matchToString(aaMatch, read1, read2, indent='', offsets=None)
Format amino acid sequence match as a string. @param aaMatch: A C{dict} returned by C{compareAaReads}. @param read1: A C{Read} instance or an instance of one of its subclasses. @param read2: A C{Read} instance or an instance of one of its subclasses. @param indent: A C{str} to indent all returned lines...
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matchCount = 0 gapMismatchCount = nonGapMismatchCount = gapGapMismatchCount = 0 read1ExtraCount = read2ExtraCount = 0 read1GapOffsets = [] read2GapOffsets = [] for offset, (a, b) in enumerate(zip_longest(read1.sequence.upper(), read2.sequence...
def compareAaReads(read1, read2, gapChars='-', offsets=None)
Compare two amino acid sequences. @param read1: A C{Read} instance or an instance of one of its subclasses. @param read2: A C{Read} instance or an instance of one of its subclasses. @param gapChars: An object supporting __contains__ with characters that should be considered to be gaps. @param o...
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result = defaultdict(set) for colorInfo in colors: readIds = colorInfo.split() color = readIds.pop(0) for readId in readIds: if os.path.isfile(readId): filename = readId if args.fasta: reads = FastaReads(filename) ...
def parseColors(colors, args)
Parse read id color specification. @param colors: A C{list} of C{str}s. Each item is of the form, e.g., 'green X Y Z...', where each of X, Y, Z, ... etc. is either a read id or the name of a FASTA or FASTQ file containing reads whose ids should be displayed with the corresponding color. Not...
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if release is None: release = get_latest_release() url = 'http://viewvc.geneontology.org/viewvc/GO-SVN/ontology-releases/%s/go-basic.obo' % release #download_file = 'go-basic_%s.obo' % release misc.http_download(url, download_file)
def download_release(download_file, release=None)
Downloads the "go-basic.obo" file for the specified release.
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with closing(requests.get( 'http://geneontology.org/ontology/go-basic.obo', stream=True)) as r: for i, l in enumerate(r.iter_lines(decode_unicode=True)): if i == 1: assert l.split(':')[0] == 'data-version' date = l.split('/')[-1] ...
def get_current_ontology_date()
Get the release date of the current Gene Ontolgo release.
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try: return TaskResult(name, True, None, function()) except Exception as exc: return TaskResult(name, False, exc, None)
def execute(function, name)
Execute a task, returning a TaskResult
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try: length = int(arg) except ValueError: # Invalid literal for int(). return value # Fail silently. if len(value) > length: return value[:length] + '...' return value
def truncatechars(value, arg)
Truncates a string after a certain number of chars. Argument: Number of chars to truncate after.
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from django.template import Context, loader from django.http import HttpResponseServerError from overseer.context_processors import default import logging import sys try: context = default(request) except Exception, e: logging.error(e, exc_info=sys.exc_info(), extra={'re...
def handler500(request)
500 error handler. Templates: `500.html` Context: None
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parser = cli.get_argument_parser(desc=desc) parser.add_argument( '-a', '--annotation-file', default='-', type=str, help=textwrap.dedent() ) parser.add_argument( '-o', '--output-file', required=True, type=str, help=textwrap.dedent() ) #parser.add_argument( ...
def get_gtf_argument_parser(desc, default_field_name='gene')
Return an argument parser with basic options for reading GTF files. Parameters ---------- desc: str Description of the ArgumentParser default_field_name: str, optional Name of field in GTF file to look for. Returns ------- `argparse.ArgumentParser` object The argume...
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from flask import current_app from . import current_jsonschemas url_map.add(Rule( "{0}/<path:path>".format(current_app.config['JSONSCHEMAS_ENDPOINT']), endpoint=current_jsonschemas.get_schema, host=current_app.config['JSONSCHEMAS_HOST']))
def jsonresolver_loader(url_map)
JSON resolver plugin that loads the schema endpoint. Injected into Invenio-Records JSON resolver.
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''' Utility function for merging multiple layouts. Args: layouts (list): A list of BIDSLayout instances to merge. Returns: A BIDSLayout containing merged files and entities. Notes: Layouts will be merged in the order of the elements in the list. I.e., the first Layout wi...
def merge_layouts(layouts)
Utility function for merging multiple layouts. Args: layouts (list): A list of BIDSLayout instances to merge. Returns: A BIDSLayout containing merged files and entities. Notes: Layouts will be merged in the order of the elements in the list. I.e., the first Layout will be up...
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if extensions is not None: if isinstance(extensions, six.string_types): extensions = [extensions] extensions = '(' + '|'.join(extensions) + ')$' if re.search(extensions, self.filename) is None: return False if domains is not N...
def _matches(self, entities=None, extensions=None, domains=None, regex_search=False)
Checks whether the file matches all of the passed entities and extensions. Args: entities (dict): A dictionary of entity names -> regex patterns. extensions (str, list): One or more file extensions to allow. domains (str, list): One or more domains the file must matc...
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keys = list(self.entities.keys()) replaced = [] for i, k in enumerate(keys): if iskeyword(k): replaced.append(k) keys[i] = '%s_' % k if replaced: safe = ['%s_' % k for k in replaced] warnings.warn("Entity names ...
def as_named_tuple(self)
Returns the File as a named tuple. The full path plus all entity key/value pairs are returned as attributes.
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''' Copy the contents of a file to a new location, with target filename defined by the current File's entities and the specified path_patterns. ''' new_filename = build_path(self.entities, path_patterns) if not new_filename: return None if new_filename[-1] ==...
def copy(self, path_patterns, symbolic_link=False, root=None, conflicts='fail')
Copy the contents of a file to a new location, with target filename defined by the current File's entities and the specified path_patterns.
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if self.map_func is not None: val = self.map_func(f) else: m = self.regex.search(f.path) val = m.group(1) if m is not None else None return self._astype(val)
def match_file(self, f, update_file=False)
Determine whether the passed file matches the Entity. Args: f (File): The File instance to match against. Returns: the matched value if a match was found, otherwise None.
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''' Return a domain if one already exists, or create a new one if not. Args: domain (str, dict): Can be one of: - The name of the Domain to return (fails if none exists) - A path to the Domain configuration file - A dictionary containing confi...
def _get_or_load_domain(self, domain)
Return a domain if one already exists, or create a new one if not. Args: domain (str, dict): Can be one of: - The name of the Domain to return (fails if none exists) - A path to the Domain configuration file - A dictionary containing configuration inf...
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''' Check file or directory against regexes in config to determine if it should be included in the index ''' filename = f if isinstance(f, six.string_types) else f.path if domains is None: domains = list(self.domains.values()) # Inject the Layout at the first p...
def _check_inclusions(self, f, domains=None)
Check file or directory against regexes in config to determine if it should be included in the index
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''' Find an Entity instance by name. Checks both name and id fields.''' if entity in self.entities: return self.entities[entity] _ent = [e for e in self.entities.values() if e.name == entity] if len(_ent) > 1: raise ValueError("Entity name '%s' matches %d entities...
def _find_entity(self, entity)
Find an Entity instance by name. Checks both name and id fields.
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''' Save the current Layout's index to a .json file. Args: filename (str): Filename to write to. Note: At the moment, this won't serialize directory-specific config files. This means reconstructed indexes will only work properly in cases where there aren't multiple ...
def save_index(self, filename)
Save the current Layout's index to a .json file. Args: filename (str): Filename to write to. Note: At the moment, this won't serialize directory-specific config files. This means reconstructed indexes will only work properly in cases where there aren't multiple layout specs...
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''' Load the Layout's index from a plaintext file. Args: filename (str): Path to the plaintext index file. reindex (bool): If True, discards entity values provided in the loaded index and instead re-indexes every file in the loaded index against t...
def load_index(self, filename, reindex=False)
Load the Layout's index from a plaintext file. Args: filename (str): Path to the plaintext index file. reindex (bool): If True, discards entity values provided in the loaded index and instead re-indexes every file in the loaded index against the entities ...
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''' Add a new Entity to tracking. ''' # Set the entity's mapping func if one was specified map_func = kwargs.get('map_func', None) if map_func is not None and not callable(kwargs['map_func']): if self.entity_mapper is None: raise ValueError("Mapping function ...
def add_entity(self, domain, **kwargs)
Add a new Entity to tracking.
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if regex_search is None: regex_search = self.regex_search result = [] filters = {} filters.update(kwargs) for filename, file in self.files.items(): if not file._matches(filters, extensions, domains, regex_search): continue ...
def get(self, return_type='tuple', target=None, extensions=None, domains=None, regex_search=None, **kwargs)
Retrieve files and/or metadata from the current Layout. Args: return_type (str): Type of result to return. Valid values: 'tuple': returns a list of namedtuples containing file name as well as attribute/value pairs for all named entities. 'file': r...
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return self._find_entity(entity).count(files)
def count(self, entity, files=False)
Return the count of unique values or files for the named entity. Args: entity (str): The name of the entity. files (bool): If True, counts the number of filenames that contain at least one value of the entity, rather than the number of unique values of th...
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try: import pandas as pd except ImportError: raise ImportError("What are you doing trying to export a Layout " "as a pandas DataFrame when you don't have " "pandas installed? Eh? Eh?") if kwargs: ...
def as_data_frame(self, **kwargs)
Return information for all Files tracked in the Layout as a pandas DataFrame. Args: kwargs: Optional keyword arguments passed on to get(). This allows one to easily select only a subset of files for export. Returns: A pandas DataFrame, where each row is a...
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''' Constructs a target filename for a file or dictionary of entities. Args: source (str, File, dict): The source data to use to construct the new file path. Must be one of: - A File object - A string giving the path of a File contained within...
def build_path(self, source, path_patterns=None, strict=False, domains=None)
Constructs a target filename for a file or dictionary of entities. Args: source (str, File, dict): The source data to use to construct the new file path. Must be one of: - A File object - A string giving the path of a File contained within the ...
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path = self.build_path(entities, path_patterns, strict, domains) if path is None: raise ValueError("Cannot construct any valid filename for " "the passed entities given available path " "patterns.") write_contents_t...
def write_contents_to_file(self, entities, path_patterns=None, contents=None, link_to=None, content_mode='text', conflicts='fail', strict=False, domains=None, index=False, index_domains=None)
Write arbitrary data to a file defined by the passed entities and path patterns. Args: entities (dict): A dictionary of entities, with Entity names in keys and values for the desired file in values. path_patterns (list): Optional path patterns to use when buildin...
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# create a child logger logger = logging.getLogger(name) # set the logger's level logger.setLevel(log_level) # set the logger's propagation attribute logger.propagate = propagate if not keep_old_handlers: # remove previously attached handlers logger.handlers = [] ...
def configure_logger(name, log_stream=sys.stdout, log_file=None, log_level=logging.INFO, keep_old_handlers=False, propagate=False)
Configures and returns a logger. This function serves to simplify the configuration of a logger that writes to a file and/or to a stream (e.g., stdout). Parameters ---------- name: str The name of the logger. Typically set to ``__name__``. log_stream: a stream object, optional ...
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# configure root logger log_level = logging.INFO if quiet: log_level = logging.WARNING elif verbose: log_level = logging.DEBUG if log_stream is None: log_stream = sys.stdout new_logger = configure_logger(name, log_stream=log_stream, ...
def get_logger(name='', log_stream=None, log_file=None, quiet=False, verbose=False)
Convenience function for getting a logger.
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stopper = threading.Event() def interval(seconds, func, *args, **kwargs): def wrapper(): if stopper.isSet(): return interval(seconds, func, *args, **kwargs) try: func(*args, **kwargs) except: # py...
def start(milliseconds, func, *args, **kwargs)
Call function every interval. Starts the timer at call time. Although this could also be a decorator, that would not initiate the time at the same time, so would require additional work. Arguments following function will be sent to function. Note that these args are part of the defining state, and un...
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result = defaultdict(list) for c1 in codons1: for c2 in codons2: distance = findDistance(c1, c2) result[distance].append([c1, c2]) return result
def codonInformation(codons1, codons2)
Take two C{list} of codons, and returns information about the min and max distance between them. @param codon1: a C{list} of codons. @param codon2: a C{list} of codons. @return: a dict whose keys are C{int} distances and whose values are lists of pairs of codons.
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try: pprint((yield from api_client.echo())) except errors.RequestError as exc: log.exception('Exception occurred: %s', exc) yield gen.Task(lambda *args, **kwargs: ioloop.IOLoop.current().stop())
def example_async_client(api_client)
Example async client.
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try: pprint(api_client.echo()) except errors.RequestError as exc: log.exception('Exception occurred: %s', exc)
def example_sync_client(api_client)
Example sync client use with.
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logging.basicConfig(level=logging.INFO) example_sync_client(SyncAPIClient()) example_async_client(AsyncAPIClient()) io_loop = ioloop.IOLoop.current() io_loop.start()
def main()
Run the examples.
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vinfo = sys.version_info if not vinfo >= (2, 7): raise SystemError('Python interpreter version >= 2.7 required, ' 'found %d.%d instead.' %(vinfo.major, vinfo.minor)) if args is None: # parse command-line arguments parser = get_argument_parser() ...
def main(args=None)
Extract protein-coding genes and store in tab-delimited text file. Parameters ---------- args: argparse.Namespace object, optional The argument values. If not specified, the values will be obtained by parsing the command line arguments using the `argparse` module. Returns ------- ...
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self.statistics = OrderedDict() for port in self.ports: port_stats = IxeStatTotal(port).get_attributes(FLAG_RDONLY, *stats) port_stats.update({c + '_rate': v for c, v in IxeStatRate(port).get_attributes(FLAG_RDONLY, *stats).items()}) ...
def read_stats(self, *stats)
Read port statistics from chassis. :param stats: list of requested statistics to read, if empty - read all statistics.
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from ixexplorer.ixe_stream import IxePacketGroupStream sleep_time = 0.1 # in cases we only want few counters but very fast we need a smaller sleep time if not stats: stats = [m.attrname for m in IxePgStats.__tcl_members__ if m.flags & FLAG_RDONLY] sleep_time = 1...
def read_stats(self, *stats)
Read stream statistics from chassis. :param stats: list of requested statistics to read, if empty - read all statistics.
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1.016867
''' Wrapper that provides common interface to all arbiters ''' if ARBITER_TYPE == "priority": _arb = arbiter_priority(req_vec, gnt_vec, gnt_idx, gnt_vld) elif (ARBITER_TYPE == "roundrobin"): _arb = arbiter_roundrobin(rst, clk, req_vec, gnt_vec, gnt_idx, gnt_vld, gnt_rdy) else: as...
def arbiter(rst, clk, req_vec, gnt_vec=None, gnt_idx=None, gnt_vld=None, gnt_rdy=None, ARBITER_TYPE="priority")
Wrapper that provides common interface to all arbiters
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2.094334
1.122986
REQ_NUM = len(req_vec) gnt_vec_s = Signal(intbv(0)[REQ_NUM:]) gnt_idx_s = Signal(intbv(0, min=0, max=REQ_NUM)) gnt_vld_s = Signal(bool(0)) @always_comb def prioroty_encoder(): gnt_vec_s.next = 0 gnt_idx_s.next = 0 gnt_vld_s.next = 0 for i in range(REQ_NUM): ...
def arbiter_priority(req_vec, gnt_vec=None, gnt_idx=None, gnt_vld=None)
Static priority arbiter: grants the request with highest priority, which is the lower index req_vec - (i) vector of request signals, req_vec[0] is with the highest priority gnt_vec - (o) optional, vector of grants, one grant per request, only one grant can be active at at time gnt_id...
1.924103
1.995567
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REQ_NUM = len(req_vec) ptr = Signal(intbv(0, min=0, max=REQ_NUM)) gnt_vec_s = Signal(intbv(0)[REQ_NUM:]) gnt_idx_s = Signal(intbv(0, min=0, max=REQ_NUM)) gnt_vld_s = Signal(bool(0)) @always(clk.posedge) def ptr_proc(): if (rst): ptr.next = REQ_NUM-1 elif (g...
def arbiter_roundrobin(rst, clk, req_vec, gnt_vec=None, gnt_idx=None, gnt_vld=None, gnt_rdy=None)
Round Robin arbiter: finds the active request with highest priority and presents its index on the gnt_idx output. req_vec - (i) vector of request signals, priority changes dynamically gnt_vec - (o) optional, vector of grants, one grant per request, only one grant can be active at at time ...
1.839521
1.897543
0.969422
seq = normalize_sequence(seq) if normalize else seq return str(vmc_digest(seq, digest_size=24))
def seq_seqhash(seq, normalize=True)
returns 24-byte Truncated Digest sequence `seq` >>> seq_seqhash("") 'z4PhNX7vuL3xVChQ1m2AB9Yg5AULVxXc' >>> seq_seqhash("ACGT") 'aKF498dAxcJAqme6QYQ7EZ07-fiw8Kw2' >>> seq_seqhash("acgt") 'aKF498dAxcJAqme6QYQ7EZ07-fiw8Kw2' >>> seq_seqhash("acgt", normalize=False) 'eFwawHHdibaZBDcs9kW3g...
11.125893
11.589757
0.959976
seq = normalize_sequence(seq) if normalize else seq bseq = seq.encode("ascii") return base64.b64encode(hashlib.sha1(bseq).digest()).decode("ascii").rstrip( '=')
def seq_seguid(seq, normalize=True)
returns seguid for sequence `seq` This seguid is compatible with BioPython's seguid. >>> seq_seguid('') '2jmj7l5rSw0yVb/vlWAYkK/YBwk' >>> seq_seguid('ACGT') 'IQiZThf2zKn/I1KtqStlEdsHYDQ' >>> seq_seguid('acgt') 'IQiZThf2zKn/I1KtqStlEdsHYDQ' >>> seq_seguid('acgt', normalize=False) ...
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5.699805
0.709729
seq = normalize_sequence(seq) if normalize else seq bseq = seq.encode("ascii") return hashlib.md5(bseq).hexdigest()
def seq_md5(seq, normalize=True)
returns unicode md5 as hex digest for sequence `seq`. >>> seq_md5('') 'd41d8cd98f00b204e9800998ecf8427e' >>> seq_md5('ACGT') 'f1f8f4bf413b16ad135722aa4591043e' >>> seq_md5('ACGT*') 'f1f8f4bf413b16ad135722aa4591043e' >>> seq_md5(' A C G T ') 'f1f8f4bf413b16ad135722aa4591043e' >>>...
3.711205
7.223423
0.513774
seq = normalize_sequence(seq) if normalize else seq bseq = seq.encode("ascii") return hashlib.sha1(bseq).hexdigest()
def seq_sha1(seq, normalize=True)
returns unicode sha1 hexdigest for sequence `seq`. >>> seq_sha1('') 'da39a3ee5e6b4b0d3255bfef95601890afd80709' >>> seq_sha1('ACGT') '2108994e17f6cca9ff2352ada92b6511db076034' >>> seq_sha1('acgt') '2108994e17f6cca9ff2352ada92b6511db076034' >>> seq_sha1('acgt', normalize=False) '948234...
4.120943
5.234412
0.787279
seq = normalize_sequence(seq) if normalize else seq bseq = seq.encode("ascii") return hashlib.sha512(bseq).hexdigest()
def seq_sha512(seq, normalize=True)
returns unicode sequence sha512 hexdigest for sequence `seq`. >>> seq_sha512('') 'cf83e1357eefb8bdf1542850d66d8007d620e4050b5715dc83f4a921d36ce9ce47d0d13c5d85f2b0ff8318d2877eec2f63b931bd47417a81a538327af927da3e' >>> seq_sha512('ACGT') '68a178f7c740c5c240aa67ba41843b119d3bf9f8b0f0ac36cf701d26672964efbd...
3.7439
5.007147
0.747711
seq = normalize_sequence(seq) if normalize else seq return {"namespace": "VMC", "accession": "GS_" + str(vmc_digest(seq))}
def seq_vmc_identifier(seq, normalize=True)
returns VMC identifier (record) for sequence `seq` See https://github.com/ga4gh/vmc >>> seq_vmc_identifier("") == {'namespace': 'VMC', 'accession': 'GS_z4PhNX7vuL3xVChQ1m2AB9Yg5AULVxXc'} True >>> seq_vmc_identifier("ACGT") == {'namespace': 'VMC', 'accession': 'GS_aKF498dAxcJAqme6QYQ7EZ07-fiw8Kw2'} ...
8.888083
8.082531
1.099666
if sort_bam: out_sam_type = 'BAM SortedByCoordinate' else: out_sam_type = 'BAM Unsorted' # template expects a list of FASTQ files fastq_files = fastq_file if isinstance(fastq_files, (str, _oldstr)): fastq_files = [fastq_file] template = _TEMPLATE_ENV.get_template(...
def map_single_end(credentials, instance_config, instance_name, script_dir, index_dir, fastq_file, output_dir, num_threads=None, seed_start_lmax=None, mismatch_nmax=None, multimap_nmax=None, splice_min_overhang=None, out_mult...
Maps single-end reads using STAR. Reads are expected in FASTQ format. By default, they are also expected to be compressed with gzip. - recommended machine type: "n1-standard-16" (60 GB of RAM, 16 vCPUs). - recommended disk size: depends on size of FASTQ files, at least 128 GB. TODO: docstring
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2.392103
0.965318
template = _TEMPLATE_ENV.get_template( os.path.join('generate_index.sh')) startup_script = template.render( script_dir=script_dir, genome_file=genome_file, annotation_file=annotation_file, splice_overhang=splice_overhang, output_dir=output_dir, num_t...
def generate_index(credentials, instance_config, instance_name, script_dir, genome_file, output_dir, annotation_file=None, splice_overhang=100, num_threads=8, chromosome_bin_bits=18, genome_memory_limit=31000000000, self_dest...
Generates a STAR index. Recommended machine type: "n1-highmem-8" (52 GB of RAM, 8 vCPUs) TODO: docstring
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2.146283
0.953784
assert isinstance(url, (str, _oldstr)) if ftp is not None: assert isinstance(ftp, ftplib.FTP) # open FTP connection if necessary close_connection = False ftp_server = 'ftp.ensembl.org' ftp_user = 'anonymous' if ftp is None: ftp = ftplib.FTP(ftp_server) ftp.login...
def get_file_checksums(url, ftp=None)
Download and parse an Ensembl CHECKSUMS file and obtain checksums. Parameters ---------- url : str The URL of the CHECKSUM file. ftp : `ftplib.FTP` or `None`, optional An FTP connection. Returns ------- `collections.OrderedDict` An ordered dictionary containing ...
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2.626192
1.077315
''' Wraps all non-list or tuple objects in a list; provides a simple way to accept flexible arguments. ''' return obj if isinstance(obj, ignore) else [obj]
def listify(obj, ignore=(list, tuple, type(None)))
Wraps all non-list or tuple objects in a list; provides a simple way to accept flexible arguments.
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2.890648
3.457695
with tarfile.open(taxdump_file) as tf: with tf.extractfile('division.dmp') as fh: df = pd.read_csv(fh, header=None, sep='|', encoding='ascii') # only keep division ids and names df = df.iloc[:, [0, 2]] # remove tab characters flanking each division name df.iloc[:,...
def _get_divisions(taxdump_file)
Returns a dictionary mapping division names to division IDs.
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3.278764
1.015055
if select_divisions and exclude_divisions: raise ValueError('Cannot specify "select_divisions" and ' '"exclude_divisions" at the same time.') select_division_ids = None exclude_division_ids = None divisions = None if select_divisions or exclude_divisi...
def _get_species_taxon_ids(taxdump_file, select_divisions=None, exclude_divisions=None)
Get a list of species taxon IDs (allow filtering by division).
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0.991717
if select_divisions and exclude_divisions: raise ValueError('Cannot specify "select_divisions" and ' '"exclude_divisions" at the same time.') select_taxon_ids = _get_species_taxon_ids( taxdump_file, select_divisions=select_divisions, exclude_di...
def get_species(taxdump_file, select_divisions=None, exclude_divisions=None, nrows=None)
Get a dataframe with species information.
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2.422601
0.999377
auto_set = IxeObject.get_auto_set() IxeObject.set_auto_set(False) for name, value in attributes.items(): setattr(self, name, value) if auto_set: self.ix_set() IxeObject.set_auto_set(auto_set)
def set_attributes(self, **attributes)
Set group of attributes without calling set between attributes regardless of global auto_set. Set will be called only after all attributes are set based on global auto_set. :param attributes: dictionary of <attribute, value> to set.
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3.603015
1.035977
handle = self._url_open('detalheCEPAction.do', {'Metodo': 'detalhe', 'TipoCep': 2, 'Posicao': posicao + 1, 'CEP': ''}) html = h...
def detalhe(self, posicao=0)
Retorna o detalhe de um CEP da última lista de resultados
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1.208852
url = 'consultaFaixaCepAction.do' data = { 'UF': uf, 'Localidade': localidade.encode('cp1252'), 'cfm': '1', 'Metodo': 'listaFaixaCEP', 'TipoConsulta': 'faixaCep', 'StartRow': '1', 'EndRow': '10', } ...
def consulta_faixa(self, localidade, uf)
Consulta site e retorna faixa para localidade
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5.050901
1.023082
if uf is None: url = 'consultaEnderecoAction.do' data = { 'relaxation': endereco.encode('ISO-8859-1'), 'TipoCep': 'ALL', 'semelhante': 'N', 'cfm': 1, 'Metodo': 'listaLogradouro', 'Ti...
def consulta(self, endereco, primeiro=False, uf=None, localidade=None, tipo=None, numero=None)
Consulta site e retorna lista de resultados
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3.21232
0.988692
retries_left = self._conn_retries while True: s = self._make_session() try: cert = None if self._client_cert and self._client_key: cert = (self._client_cert, self._client_key) elif self._client_cert: ...
def _request(self, url, *, method='GET', headers=None, data=None, result_callback=None)
Perform synchronous request. :param str url: request URL. :param str method: request method. :param object data: JSON-encodable object. :param object -> object result_callback: result callback. :rtype: dict :raise: APIError
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sess = requests.Session() sess.mount('http://', requests.adapters.HTTPAdapter(max_retries=False)) sess.mount('https://', requests.adapters.HTTPAdapter(max_retries=False)) return sess
def _make_session()
Create session object. :rtype: requests.Session
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1.010236
payload = { 'attachment': 'true', "filters": json.dumps({ "op": "and", "content": [ { "op":"in", "content":{ "field":"cases.project.program.name", "value":["TCGA"]}},...
def get_clinical_data(tcga_id)
Get clinical data for a TCGA project. Parameters ---------- tcga_id : str The TCGA project ID. Returns ------- `pandas.DataFrame` The clinical data.abs Notes ----- Clinical data is associated with individual cases (patients). These correspond to rows in...
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0.989777
payload = { 'attachment': 'true', "filters": json.dumps({ "op": "and", "content": [ { "op":"in", "content":{ "field":"cases.project.program.name", "value":["TCGA"]}},...
def get_biospecimen_data(tcga_id)
Get biospecimen data for a TCGA project. Parameters ---------- tcga_id : str The TCGA project ID. Returns ------- `pandas.DataFrame` The biospecmin data. Notes ----- Biospecimen data is associated with individual vials. TCGA vials correspond to portions...
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2.941077
0.989012
payload = { "filters": json.dumps({ "op": "and", "content" : [ { "op":"in", "content":{ "field":"cases.project.program.name", "value":["TCGA"]}}, { ...
def get_masked_cnv_manifest(tcga_id)
Get manifest for masked TCGA copy-number variation data. Params ------ tcga_id : str The TCGA project ID. download_file : str The path of the download file. Returns ------- `pandas.DataFrame` The manifest.
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2.608956
0.924932
assert isinstance(file_ids, Iterable) # query TCGA API to get sample barcodes associated with file IDs payload = { "filters":json.dumps({ "op":"in", "content":{ "field":"files.file_id", "value": list(file_ids), } }), ...
def get_file_samples(file_ids)
Get TCGA associated sample barcodes for a list of file IDs. Params ------ file_ids : Iterable The file IDs. Returns ------- `pandas.Series` Series containing file IDs as index and corresponding sample barcodes.
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1.041049
assert isinstance(file_samples, pd.DataFrame) df = file_samples # use shorter variable name # sort data frame by file ID df = df.sort_values('file_id') # - some samples have multiple files with the same barcode, # corresponding to different aliquots # get rid of those duplicates ...
def get_unique_sample_files(file_samples)
Filter file_sample data frame to only keep one file per sample. Params ------ file_samples : `pandas.DataFrame` A data frame containing a mapping between file IDs and sample barcodes. This type of data frame is returned by :meth:`get_file_samples`. Returns ------- `...
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1.04342
df = biospecimen # use shorter variable name # get rid of FFPE samples num_before = len(df.index) df = df.loc[~df['is_ffpe']] logger.info('Excluded %d files associated with FFPE samples ' '(out of %d files in total).', num_before - len(df.index), num_before) ...
def get_fresh_primary_tumors(biospecimen)
Filter biospecimen data to only keep non-FFPE primary tumor samples. Parameters ---------- biospecimen : `pandas.DataFrame` The biospecimen data frame. This type of data frame is returned by :meth:`get_biospecimen_data`. Returns ------- `pandas.DataFrame` The fi...
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3.191179
1.007907
seen = set() add = seen.add for read in reads: hash_ = md5(read.sequence.encode('UTF-8')).digest() if hash_ not in seen: add(hash_) yield read
def dedupFasta(reads)
Remove sequence duplicates (based on sequence) from FASTA. @param reads: a C{dark.reads.Reads} instance. @return: a generator of C{dark.reads.Read} instances with no duplicates.
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4.095188
0.858556
sequences = sorted(sequences, key=lambda s: len(s.seq), reverse=True) seen = set() for s in sequences: thisSeq = str(s.seq) thisHash = md5(thisSeq.encode('UTF-8')).digest() if thisHash not in seen: # Add prefixes. newHash = md5() for nucl in t...
def dePrefixAndSuffixFasta(sequences)
sequences: an iterator producing Bio.Seq sequences. return: a generator of sequences with no duplicates and no fully contained subsequences.
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2.748515
0.986131
reads = {} firstFile = fastaFiles.pop(0) for seq in SeqIO.parse(firstFile, 'fasta'): reads[seq.id] = seq for fastaFile in fastaFiles: for seq in SeqIO.parse(fastaFile, 'fasta'): # Make sure that reads with the same id have the same sequence. if seq.id in rea...
def fastaSubtract(fastaFiles)
Given a list of open file descriptors, each with FASTA content, remove the reads found in the 2nd, 3rd, etc files from the first file in the list. @param fastaFiles: a C{list} of FASTA filenames. @raises IndexError: if passed an empty list. @return: An iterator producing C{Bio.SeqRecord} instances ...
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2.626453
0.929478
# Read sequences from a FASTA file, if given. if filename: reads = FastaReads(filename, readClass=readClass, upperCase=upperCase) else: reads = Reads() # Add any individually specified subject sequences. if sequences: for count, sequence in enumerate(sequences, start=1)...
def combineReads(filename, sequences, readClass=DNARead, upperCase=False, idPrefix='command-line-read-')
Combine FASTA reads from a file and/or sequence strings. @param filename: A C{str} file name containing FASTA reads. @param sequences: A C{list} of C{str} sequences. If a sequence contains spaces, the last field (after splitting on spaces) will be used as the sequence and the first fields will ...
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3.253696
0.991795
count = 0 for _file in self._files: with asHandle(_file) as fp: # Duplicate some code here so as not to test # self._upperCase in the loop. if self._upperCase: for seq in SeqIO.parse(fp, 'fasta'): ...
def iter(self)
Iterate over the sequences in the files in self.files_, yielding each as an instance of the desired read class.
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3.733465
1.154531
if self._upperCase: for id_ in self._fasta: yield self._readClass(id_, str(self._fasta[id_]).upper()) else: for id_ in self._fasta: yield self._readClass(id_, str(self._fasta[id_]))
def iter(self)
Iterate over the sequences in the files in self.files_, yielding each as an instance of the desired read class.
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3.059494
1.31367
cur = self._connection.cursor() cur.execute('SELECT name FROM files WHERE id = ?', (fileNumber,)) row = cur.fetchone() if row is None: return None else: return row[0]
def _getFilename(self, fileNumber)
Given a file number, get its name (if any). @param fileNumber: An C{int} file number. @return: A C{str} file name or C{None} if a file with that number has not been added.
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2.514549
0.977765
cur = self._connection.cursor() cur.execute('SELECT id FROM files WHERE name = ?', (filename,)) row = cur.fetchone() if row is None: return None else: return row[0]
def _getFileNumber(self, filename)
Given a file name, get its file number (if any). @param filename: A C{str} file name. @return: An C{int} file number or C{None} if no file with that name has been added.
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2.566328
0.935598
cur = self._connection.cursor() try: cur.execute('INSERT INTO files(name) VALUES (?)', (filename,)) except sqlite3.IntegrityError as e: if str(e).find('UNIQUE constraint failed') > -1: raise ValueError('Duplicate file name: %r' % filename) ...
def _addFilename(self, filename)
Add a new file name. @param filename: A C{str} file name. @raise ValueError: If a file with this name has already been added. @return: The C{int} id of the newly added file.
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2.621535
1.020588
endswith = filename.lower().endswith if endswith('.bgz') or endswith('.gz'): useBgzf = True elif endswith('.bz2'): raise ValueError( 'Compressed FASTA is only supported in BGZF format. Use ' 'bgzip to compresss your FASTA.') ...
def addFile(self, filename)
Add a new FASTA file of sequences. @param filename: A C{str} file name, with the file in FASTA format. This file must (obviously) exist at indexing time. When __getitem__ is used to access sequences, it is possible to provide a C{fastaDirectory} argument to our C{__init__} t...
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2.756654
1.040335
cur = self._connection.cursor() cur.execute( 'SELECT fileNumber, offset FROM sequences WHERE id = ?', (id_,)) row = cur.fetchone() if row is None: return None else: return self._getFilename(row[0]), row[1]
def _find(self, id_)
Find the filename and offset of a sequence, given its id. @param id_: A C{str} sequence id. @return: A 2-tuple, containing the C{str} file name and C{int} offset within that file of the sequence.
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3.090882
1.212539
# use regular expression with negative lookbehind to make sure we don't # split on escaped semicolons ("\;") attr_sep = re.compile(r'(?<!\\)\s*;\s*') attr = {} atts = attr_sep.split(s) for a in atts: #print(a) kv = a.split(' ', maxsplit=1) if len(kv) == 2: ...
def parse_attributes(s)
Parses the ``attribute`` string of a GFF/GTF annotation. Parameters ---------- s : str The attribute string. Returns ------- dict A dictionary containing attribute name/value pairs. Notes ----- The ``attribute`` string is the 9th field of each annotation (row), ...
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0.980781
if len(record.alignments) == 0: return 0 if record.descriptions[0].e > 1e-120: return 0 print(record.query, end=' ') for i, alignment in enumerate(record.alignments): print(record.descriptions[i].e, end=' ') for hspIndex, hsp in enumerate(alignment.hsps, start=1): ...
def printBlastRecordForDerek(record)
This is a hacked version of printBlastRecord that I wrote in Addenbrookes hospital so Derek could try hacking on the reads that had low e values. It's called by bin/print-blast-xml-for-derek.py
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2.579159
1.033394
match = _PATHOGEN_RE.match(names) if match: proteinName = match.group(1).strip() pathogenName = match.group(2).strip() else: proteinName = names pathogenName = _NO_PATHOGEN_NAME return proteinName, pathogenName
def splitNames(names)
Split a sequence id string like "Protein name [pathogen name]" into two pieces using the final square brackets to delimit the pathogen name. @param names: A C{str} "protein name [pathogen name]" string. @return: A 2-C{tuple} giving the C{str} protein name and C{str} pathogen name. If C{names} canno...
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2.095714
1.570103
result = Counter() if filenames: for filename in filenames: for protein in FastaReads(filename): _, pathogenName = splitNames(protein.id) if pathogenName != _NO_PATHOGEN_NAME: result[pathogenName] += 1 return result
def getPathogenProteinCounts(filenames)
Get the number of proteins for each pathogen in C{filenames}. @param filenames: Either C{None} or a C{list} of C{str} FASTA file names. If C{None} an empty C{Counter} is returned. If FASTA file names are given, their sequence ids should have the format used in the NCBI bacterial and viral p...
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5.230089
0.992824
pathogenIndex = self._pathogens.setdefault(pathogenName, len(self._pathogens)) sampleIndex = self._samples.setdefault(sampleName, len(self._samples)) try: return self._readsFilenames[(pathogenIndex, sampleIndex)] ex...
def add(self, pathogenName, sampleName)
Add a (pathogen name, sample name) combination and get its FASTA/FASTQ file name and unique read count. Write the FASTA/FASTQ file if it does not already exist. Save the unique read count into C{self._proteinGrouper}. @param pathogenName: A C{str} pathogen name. @param sampleNam...
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3.267469
1.179597
pathogenIndex = self._pathogens[pathogenName] sampleIndex = self._samples[sampleName] return self._readsFilenames[(pathogenIndex, sampleIndex)]
def lookup(self, pathogenName, sampleName)
Look up a pathogen name, sample name combination and get its FASTA/FASTQ file name and unique read count. This method should be used instead of C{add} in situations where you want an exception to be raised if a pathogen/sample combination has not already been passed to C{add}. ...
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3.950945
1.007846
print('\n'.join( '%d %s' % (index, name) for (index, name) in sorted((index, name) for (name, index) in self._samples.items()) ), file=fp)
def writeSampleIndex(self, fp)
Write a file of sample indices and names, sorted by index. @param fp: A file-like object, opened for writing.
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3.488864
1.096946
print('\n'.join( '%d %s' % (index, name) for (index, name) in sorted((index, name) for (name, index) in self._pathogens.items()) ), file=fp)
def writePathogenIndex(self, fp)
Write a file of pathogen indices and names, sorted by index. @param fp: A file-like object, opened for writing.
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3.427166
1.123854
return ( 'Overall, proteins from %d pathogen%s were found in %d sample%s.' % (len(self.pathogenNames), '' if len(self.pathogenNames) == 1 else 's', len(self.sampleNames), '' if len(self.sampleNames) == 1 else 's'))
def _title(self)
Create a title summarizing the pathogens and samples. @return: A C{str} title.
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1.229269