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7 Ridiculously Expensive Lego Sets That Shouldn’t Exist Lego sets are incredibly serious business. There are some collectors out there willing to spend almost $10,000 on some of the rarest sets. With the advent of the Lego video games, the sets have gotten more and more popular as people are reminded of Legos almost constantly. Video games have greatly influenced Legos also, as there are Minecraft and other sets that exist. I remember playing with Legos as a child and bringing my imagination to life with them. Now, if you're willing to fork over the cash, someone else can do the imagining for you while you just put it together. Let's take a look at some of the most expensive Lego sets we can't believe exist. blog comments powered by Disqus "Like" CheatCC on Facebook
dclm_baseline
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tagFirst TimeFarm Girl Farm Girl Darla lay in bed wondering if he would do it to her tonight. He came to her bed almost every night now. There had been a time when she was afraid and dreaded the pain, but she was used to it now. Darla was a cute blonde who had grown up on an isolated farm too far away to attend public school, so her mother had home schooled her. When she turned 18 she was sent to the city to live with a young couple and help with the housework. Jerry, the husband, was a silent, intimidating man with black hair and brown eyes. He seldom spoke to Darla, didn't even seem to realize she was around. Susan, his wife, was kind to Darla. She was a small, beautiful woman with brown hair and blue eyes. Her breasts and belly seemed to Darla to be a little bit too fat compared to her arms and legs. The housework wasn't difficult. Susan did the cooking and a woman came in twice a week to do the laundry and heavy cleaning. Jerry worked late most nights, and after supper Susan often invited Darla to watch television with her. They had not had television on the farm, so Darla was fascinated by the programs. She didn't understand a lot of the programs, but she was learning. Both women turned in about eleven. One night after Darla had been in the city for a few weeks Susan went to stay with her sister for a few days, and Darla and Jerry were home alone. Darla was sitting on the sofa in front of the TV, and Jerry came over and sat down beside her. "What kind of programs do you like to watch, Darla?" asked Jerry. "Oh, whatever you like. I don't have any favorites." Jerry switched to a porn channel and watched Darla out of the corner of his eye to see her reaction. She seemed stunned, yet interested in the action on the screen. He moved closer to her and put his arm across her shoulders; then he put his hand on her thigh. He moved it up toward her crotch and felt heat emanating from that area. "That looks like fun, doesn't it?" asked Jerry. "Would you like to try?" "I don't know. It looks like it would hurt." "Maybe a little at first, but not much if it's done right. I'll show you some time," Jerry promised. "Well, maybe some time. I think I'll go to bed now." Darla lay there thinking about the movie. She had strange feelings, and her hand involuntarily moved toward her sex until she remembered she had been taught never to touch herself there and moved her hand back under her pillow. After a while she drifted off to sleep, and sometime later was awakened by someone in bed with her. He was actually on top of her and pressing something hard into her belly. He began kissing her mouth. Darla had never been kissed on the mouth before and was disgusted, especially when he stuck his tongue in her mouth. She pushed him off, but he told her to lie still. In the half-light from the window she could see Jerry's profile. He lifted her nightgown above her breasts and began to suck on them. She had seen animals feed their babies that way and wondered if Jerry was getting milk from her breasts, and if so why he would do such a thing. He lowered his hand to her crotch and cupped her mound with his hand, his fingers pressing against the entrance to her vagina through her panties. He slipped his fingers inside them and pressed his finger into her vagina until it started to hurt. After kissing her again he left her bed. The next night he worked very late, but after he came home he got back in Darla's bed again, and again he kissed her and raised her nightgown to suckle her breasts while poking her belly with the hard thing. As he nursed he pulled her panties off and stuck a finger in her vagina. He moved it in and out, and when he stuck it in too far it hurt. He raised himself up, and straddled her. She realized the hard thing was attached to his body between his legs. She had seen penises on male animals on the farm and began to make the connection to the one Jerry had. Her parents had made sure she never saw animals mating, so she had no idea what it was for until she watched the porn movie with Jerry. Jerry gently stroked her clitoris and between her labia with his penis. Darla was ashamed that she thought it sort of felt good because she had always been taught never to touch herself there, but maybe because Jerry was doing instead of her it was ok. He stroked on down to her vagina and paused there pulsing against the entrance. He reared back and pushed his penis into her. She struggled and let out a little yelp from the pain. Jerry hushed her and said it would stop hurting in a minute. It didn't though, and it hurt even more when he began to thrust in and out. He kept it up until she felt something gush inside her and his penis began to jerk. He stopped thrusting then and collapsed on top of her, his penis continuing to spasm inside her. As the spasms subsided his penis began to soften, and he pulled it out. When Darla got up she saw blood on the sheet, but it wasn't as much as when she had her period, and she didn't continue to bleed. Darla was very sore the next day but was able to do her work. Jerry came to her again that night, inserted his penis in her vagina again and stroked in and out until he shot the liquid into her again. It hurt because she was still sore from the night before, but it felt good in a way too. She thought of it as him riding her, but over the weeks the more he rode her the less it hurt, and the better it felt. Soon she was bucking her hips to meet his thrusts when he did it to her. She liked the feeling when he felt her breasts and suckled them. When Susan came home Darla noticed she was getting fatter in the belly. It sort of reminded Darla of how farm animals bulged out when they were pregnant. She wondered if Susan could be pregnant. Meanwhile Jerry had been coming to Darla's bed almost every night. Darla enjoyed the things he did to her and prepared for him by sleeping with her panties off and her legs spread so he could start riding her with the least delay. She wondered if he would still do it to her when she started her period, but she never bled again after the first night he rode her, and her period didn't come when it was supposed to. Now it felt better than ever when he sucked her breasts. They were getting bigger and ached. The sucking helped ease the ache. The soreness in her vagina from the first time he rode her was long gone too. Now she enjoyed the feel of his penis in her, and often she got a most wonderful feeling that caused spasms in her vagina and went all through her body. The first time it happened to her Jerry noticed and asked her if she had climaxed. She didn't know what that meant but it happened more and more often, and she began to think of the feeling as climax. She thought of it as Jerry riding her to climax, and wondered if his jerking and gushing inside her meant he felt a climax too. Susan's belly kept getting bigger, and Darla was certain her employer was going to have a baby. She began to wonder if she could be pregnant too because her belly was swelling. On night after he had ridden her Darla asked Jerry about it. He hefted her breasts, pressed her belly and answered that he thought so. One day Susan went to the hospital to have her baby. While Susan was gone Jerry rode Darla every night and stayed to ride her once or twice again. She would always wake up in the morning to find him riding her one more time before he left for work. She loved the attention. After Susan came home from the hospital with the baby Jerry rode Darla less and less often as the months passed. Her belly was getting so big now that it wasn't comfortable anyway. A nursemaid named Patty - a voluptuous redhead with green eyes - had been hired to help Susan with the baby, and she took over some of Darla's chores too. One day Darla began having cramps, and Susan said the baby was coming and took her to the hospital. Having the baby was scary and it hurt, but it was a cute little thing, and when it sucked her breasts it was a different feeling from when Jerry did it. It gave her relief from the fullness, but it didn't make her want to be ridden like Jerry's nursing did. Darla was glad that soon he also started nursing her and riding her again, but he didn't do it as often now. Darla began to understand that being ridden by Jerry was what had put the baby in her belly, and he had ridden Susan to give her a baby too, and maybe he had given her another one because she looked like she was pregnant again, and so did Patty. Report Story byIole© 4 comments/ 92121 views/ 10 favorites Share the love Similar stories Also in this series Tags For This Story Report a Bug 1 Pages:1 Please Rate This Submission: Please Rate This Submission: • 1 • 2 • 3 • 4 • 5 Please wait Favorite Author Favorite Story hearttopdollar, osc4321 and 8 other people favorited this story!  by Anonymous Add a Post comment as (click to select): You may also listen to a recording of the characters. Preview comment Forgot your password? Please wait Change picture Your current user avatar, all sizes: You have a new user avatar waiting for moderation. Select new user avatar:
dclm_baseline
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\section{General Antiperiodicity Property} Tags: Antiperiodic Functions \begin{theorem} Let $f: X \to X$ be an antiperiodic function, where $X$ is either $\R$ or $\C$. Let $L$ be an antiperiodic element of $f$. Let $n \in \Z$ be an integer. :If $n$ is even, then $n L$ is a periodic element of $f$. :If $n$ is odd, then $n L$ is an antiperiodic element of $f$. \end{theorem} \begin{proof} Suppose that $X = \C$. \end{proof}
math_pile
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Log in No account? Create an account So anyway, Not-review: Rough Cuts - The Victorian in the Wall  11th-Nov-2011 08:49 pm The Rough Cuts brand at the Royal Court presents works-in-progress, and in the case of Will Adamsdale's The Victorian in the Wall a piece very early on in its development: According to Adamsdale's introduction they've only been devising it for the last few days, from an idea he'd been knocking around for a few months. Presumably the idea behind letting an audience in to these two performances is to see if it's worth working on any more, and I would say it is: Adamsdale plays a lazy writer who's getting a wall knocked down in his house, which has the side-effect of releasing the ghost of a Victorian man. Co-devisers Jason Barnett, Chris Branch, Matthew Steet and Melanie Wilson play all other roles and provide live sound effects to comic effect, and if they can find a way to transfer the ramshackle charm into a fully-staged show it could be very entertaining. They need to decide how much to use the chorus of cockney neighbours though, they either need to be ditched completely or integrated a lot more. As the show stood tonight, they appeared at the start and then when they eventually reappeared later it took me a while to remember who they were. Fun though. Rough Cuts - The Victorian in the Wall by Will Adamsdale is booking until the 12th of November at the Royal Court Jerwood Theatre Upstairs. This page was loaded Sep 22nd 2017, 10:46 pm GMT.
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Wednesday, October 29, 2008 Some brief arguments for dualism, Part IV 1. Hello Professor Feser. Thank you for providing another thoughtful article. I've been interested in your discussions on these subjects ever since I read "The Philosophy of Mind: A Short Introduction." I have not read "The Last Superstition" yet, but I do have it on order, so excuse me if I ask anything that's already been addressed by the book. It seems the central argument in the later part of this article is that the concept of universals are not material, therefore thoughts about the concept of universals are not material. Is my understanding here correct? Would not the materialist reply that this is indeed a "soul of the gaps" argument? i.e. We simply don't know how abstract concepts are formed in the brain yet. However, we are well on our way to showing how other types of thoughts are formed. Therefore it's reasonable to assume that abstract thoughts will be eventually discovered in the same way? 2. Ed This is a great article and I will certainly get my hands on your book. What do you think of the work of Saul Kripke and Hillary Putnam on definitions and its relations to philosophy of mind? Does it lend credence to the Aquinas definition of essential essences? 3. Hello Chen-song, No, the point is that an abstract concept could not, even in theory, be material, given that concepts are determinate and material things are indeterminate. So to suggest that we'll eventually "discover" that concepts are properties of the brain is like saying we might someday "discover" that 2 + 2 = 5. Hello Damien, Thanks. Re: Kripke and Putnam, while their revival of the idea of essences is a welcome development, from an Aristotelian-Thomistic point of view it is still inadequate. The differences between Aristotelian essentialism and contemporay Kripke-Putnam essentialism have been discussed by David Oderberg in his book Real Essentialism and his article "How to Win Essence Back from Essentialists," and by Gyula Klima in his article "Contemporary 'Essentialism' vs. Aristotelian Essentialism." Oderberg's and Klima's articles are available on their respective websites, which you'll find links to here on my blog under "Recommended philosophers' websites." 4. Thank you for the reply. So the idea here is that thoughts about abstract concepts contain abstract concepts, and so those thoughts are not reducible to material origins? I just wanted to get the idea clear here. Also, I found a rather disturbing development in this New Scientist article: See the confusion of any objection to materialism with ID/creationism displayed here. It could be that in the future, any non-materialist might get tainted with the "creationist" brush over a debate that doesn't even concern science at all. 5. Prof Feser, I like to observe, in connection, with a previous post actually, that CS Lewis held thinking to be an instance of Supernature and that mind does move atoms about. (Miracles). I had thought this picture to be unsatisfactory and now I feel I have got a better picture of soul-body relation from your post. 6. Materialism gets itself into a hole in the foundational problems of quantum mechanics what with conscious observers required to collapse wavefunctions and associated paradoxes. The very matter seems to be quite immaterial. The existing interpretations of quantum mechanics all suffer from one problem or another. The current favorite though seems to be Many-World interpretation. I wonder if your viewpoint based upon Aristotle could provide an alternative interpretation of quantum mechanics. It would be quite a sensation and also very muh needed as every wonderful theory needs applications 7. While I respect the metaphysical realist position to some extent--a better argument for immaterialism of some sort than intentionality, I would aver-- it's again a matter of addressing competing claims, and not merely saying it's impossible for empiricists, nominalists, materialists, and the rest to account for universals (or apparent universals), logical/mathematical entities, taxonomies, "Justice", beauty etc. I don't pretend to be a master of platonic or Aristotelian metaphysics, but I strongly suspect that taxonomy was worked out over centuries: the noun "mammal" describes a class of warm-blooded, hairy vertebrates (attributes, as y'all say) which exist in the real, observable world. However quotidian or even vulgar that seems, that's a universal (at least on earth). The terms/nomenclature could be changed, but the class is out there in some sense. Cardinal numbers, triangles, functions, modus ponens, etc. might seem like a slightly different problem (and it is), but I believe that the class of triangles are more like Mammalia--abstracted from experience--than it is, well, the mind of JHVH (or Plato). Blind people would not likely have developed geometry (or physics, if not mathematics as a whole), regardless of what a Kant or Plato insists upon. Again, it's a matter of the lack of knowledge of learning mechanisms: what seemed mysterious (or knowledge dependent on an immortal soul) to Aristotle's students or Aquinas is not so mysterious now, and in a few centuries the learning process associated with mathematical knowledge will probably be neurologically mapped out. Not really so sublime, but then neither is human history...... 8. Isn't this an example of the content fallacy that Pasnau has shown Aquinas to fall into? Just because we are thinking of something red doesn't mean our thoughts must be red. Likewise, just because we are thinking of something immaterial doesn't mean our thoughts must be immaterial. 9. That isn't the argument, and there is no "content fallacy" -- one of these days I'm going to write up a reply to Pasnau. Briefly, though, the claim isn't "The objects of thought are immaterial, so thoughts are immaterial," which would of course be fallacious. The argument is rather "The objects of thought have property X (e.g. determinacy), which makes them immaterial; and since thoughts too have this property, they also are immaterial." No fallacy. 10. I have a question. You say the following: But doesn't that also hold true for a material triangle? That is a material triangle is not an approximation of triangularity, because no single triangle is triangularity, even if it were a perfect material triangle. I think to argue that triangularity can't be material because all material triangles are imperfect is a flawed argument. Even if a material triangle was perfect, it still wouldn't be triangularity. So I don't think argument argues that triangularity can't be material. Am I misunderstanding something? 11. I was led to this post right after reading Freddoso's reference to it in a footnote to his updated, revised (2012) paper. The note reads: "Edward Feser helpfully reviews various of these arguments in a blog entry entitled “Some brief arguments for dualism, part IV” ( and in the three other parts linked at the beginning of that entry. [...] Unlike Feser, I am very uneasy describing St. Thomas’s position as a form of dualism — even ‘hylemorphic dualism’ — since it is precisely the unity of the human being that St. Thomas wants to emphasize over against Plato’s position, which (as he interprets it) posits many substantial forms in the human composite. (The term ‘hylemorphic dualism’ originates, I believe, with David Oderberg in Real Essentialism (New York: Routledge, 2007).) This is largely a verbal disagreement, but I for one resist making Thomistic philosophical anthropology conform to what I believe to be the illegitimate contemporary taxonomy of ‘solutions’ to the alleged ‘mind-body problem’, according to which each solution is either a type of materialism or a type of dualism." - A. Freddoso, 2012. "Oh, My Soul, There's Animals and Animals..." I remember reading Orderberg and thinking to myself: "very interesting.. hmm.. right on point... hmmm... hylemorphic DUALISM? what?" I've always thought it is a rather infelicitous way of characterizing Aristotelian-Thomistic hylemorphism. Freddoso agrees with me! :) 12. OK, I realize I'm a few years late with this comment, but: Cannot these abstract, exact, determinate concepts, like triangularity, or addition, or whatever, also be coded into a computer program? And if they can, does that make the computer program immaterial too? 13. The computer program is programmed by us to produce certain symbols as outputs when certain symbols are given as inputs. Those symbols themselves, as well as the algorithms that produce them, have no meaning apart from an interpreting mind. The computer program is material. The programming and interpretation of the program, however, is done by minds, which must in principle be immaterial. 14. @ John, "I think to argue that triangularity can't be material because all material triangles are imperfect is a flawed argument." But that is not the argument. It wouldn't matter if this or that material triangle actually had, e.g., perfectly straight sides; it would still be a triangle of one and only one kind (i.e. either scalene, isosceles or equilateral). It would also have other features that were accidental limits: e.g., it would be of such-and-such a size; whereas, triangles can be of any size, big or small. But any material triangle is thus going to be limited; whereas, the concept of triangularity is not so limited but includes all possible triangles. No material triangle could at the same time be all possible triangles (indeed this would involve impossible contradictions) simply and exactly because it is material. Moreover, any material triangle is also, e.g., subject to change because matter can always at least potentially change and take on a different form; whereas, triangularity does not change. This or that triangle could be made of a composite or patchwork of material or a single material but also potentially many other kinds of material; and each kind of material is in its turn potentially a different material. 15. While reading The Last Superstition and Philosophy of mind, I found myself wondering about something. It seems that much time is spent discussing mind vs matter. And a strong (irrefutable, in my opinion) case is made for mind != matter. But what about energy? Energy is just as mysterious and immaterial and is just as similarly attached to matter. Why couldn't mind be energy? Or why, at least, does this not get discussed?
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Affiche La croisée dans un labyrinthe étranger • 2 saisons • 12 épisodes • Début : • Statut : • Hashtag : Durant la seconde moitié du 19ème siècle, l'Europe fut intriguée par la culture japonaise. Une jeune japonaise appelée Yune arrive en France et va commencer à travailler dans les parties reculées de la ville de Paris, plus précisément dans un magasin d'artisanat appelé "Enseignes du Roy". Elle et Claude, le propriétaire du magasin, vont beaucoup apprendre des différences culturelles qui les séparent. C'est l'histoire du séjour de Yune à Paris. Saisons & épisodes Les résumés de tous les épisodes de La croisée dans un labyrinthe étranger S01E01 Entrée 18/06/2011 Yune arrives at the Enseignes du Roy after a long trip from Japan with Oscar. Oscar's grandson Claude instantly experiences culture shock upon the presence of a Japonaise in French soil, and after seeing the little girl's attempts to embrace French culture, he begins to accept the Japanese culture as well. S01E02 Fromage 11/07/2011 In order to learn more about living in France, Yune starts out by embracing French food. Yune clearly struggles from eating cheese and drinking coffee, but Oscar decides to give her much more comfortable food to eat for the meantime. Claude would also take Yune to a walk to the market to learn about food the French usually eat. S01E03 Labyrinthe du Japon 18/07/2011 As Claude is having trouble coming up with an idea for a sign for a music shop, he finds inspiration after seeing Yune write out a letter to her sister. Meanwhile, Oscar learns that Yune's kimono had been bought by the upper-class Blanche family, the youngest of which, Alice, showing excitement when she hears rumours about Yune. S01E04 Eau et Lumière 25/07/2011 Alice becomes determined to invite Yune over for tea, but Claude is not so keen on the idea. After Alice keeps pestering them, Yune agrees to go to the Blanche household. Although Alice makes various attempts to get Yune to stay with her, even offering to return her kimono free of charge, Yune declines in order to hold up a promise to make sukiyaki for the Claudels. S01E05 Perdus 01/08/2011 Yune feels downhearted when she is scorned by Claude for being too friendly towards customers. When a scruffy boy takes advantage of Yune's gullibility and steals a candlestick, she chases after him but loses him. Furthermore, she forgets her way back to the Enseignes du Roy, unable to ask others for help and becoming suspicious towards those who do try to help her. She is eventually found by Claude who takes her back home. S01E06 Crinoline 08/08/2011 Alice visits the Enseignes du Roy to invite Yune to have her photograph taken. Alice follows Yune's advice on putting on a kimono whilst Yune tries on one of Alice's dresses. Whilst getting their photo taken, Yune notices Alice's sister, Camille, feeling downhearted, prompting a reaction when mentioning it to Claude. S01E07 Lucarne 15/08/2011 Claude scolds Yune for trying to sympaphize with the boy from before. Yune soon ends up collapsing from a fever, leading Claude to feel guilty about what he said to her. He goes to see Alice, who sends for a doctor and gives him a recipe for Japanese porridge. He also helps deliver a flower the boy made for Yune. S01E08 Chambre d'enfant 22/08/2011 As Claude drops Yune off at a tea party with Alice, he is brought to see Camille, who he used to play with in his childhood. After talking about their local fairy tales, Alice shows Yune the nursery she grew up in, where Camille decides to give her a dress that belonged to Alice when she told her a fascinating story. S01E09 The Secret Garden 29/08/2011 As Yune and Alice continue to play together, Claude recalls the times he used to play with Camille. Claude almost always came over to the Blanche's garden to play with Camille, but she was unwillingly to leave the confines of the mansion herself. One day, Camille snuck out of the mansion in order to see Claude, later explaining to him that she didn't want to leave the mansion as it would put him in trouble. S01E10 Phantasmagoria 05/09/2011 As Claude goes to see one of his late father's old clients about a commission, Yune finds an old slide projector, which Oscar decides to show off to her and Alice. Yune is reminded of the time she used to make shadow puppets with her sister. Afterwards, after Oscar teaches the girls how to make phenakistoscopes, one of his friends, Alan, helps him put on a public projector show. S01E11 Prayer 12/09/2011 Alice invites Yune to come to an exhibition at the Grand Magasin, but Claude is strongly against it for some reason. As a reprise, Claude takes Yune and Oscar to a picnic in the park. After seeing her upset whilst thinking about home, Claude asks Yune to tell him about her sister, Shione. As Shione was often looked at strangly because of her pale blue eyes, Yune, who was weak at the time, made a prayer that she would only be able to look at her. However, as time went on and Yune became stronger, Shione's grew weak and went blind, which Yune blames herself for to this day. However, Oscar assures her that Yune's words made Shione happy. S01E12 Cats on the Roof 19/09/2011 Yune hears about a black cat that ran away from one of the stores. Later, Claude yells at Yune when she touches a pair of gloves with belonged to his late father. When Yune hears a bell, she assumes it to be the cat she heard about and goes to search for it, which causes Claude to worry when he can't find her. As Claude gets help from Alice and the other Galerie shopkeepers, he finds Yune up on the roof of the Galerie. After getting her to safety, Claude tells Yune about his father and agrees to take her to the Grand Magasin at some point. Afterwards, Claude returns Yune to the Galerie where everyone is waiting. S00E01 Ikoku Meiro no Croisee The Animation Special (Episode 4.5) 29/07/2011 According to the official website, episode 4.5 of of Ikoku Meiro no Croisée will be included in the third volume of the Blu-ray & DVD. The episode streamed for a limited time on ShowTime, the official online streaming site for Ikoku Meiro no Croisée. S00E02 Yune & Alice 1 21/09/2011 S00E03 Picture Drama 1 26/10/2011 S00E04 Yune & Alice 2 26/10/2011 S00E07 Picture Drama 2 25/11/2011 S00E08 Yune & Alice 3 25/11/2011 S00E10 Picture Drama 3 21/12/2011 S00E11 Yune & Alice 4 21/12/2011 S00E12 Picture Drama 4 25/01/2012 S00E13 Yune & Alice 5 25/01/2012 S00E14 Picture Drama 5 22/02/2012 S00E15 Yune & Alice 6 22/02/2012 S00E16 Picture Drama 6 21/03/2012 S00E17 Yune & Alice 7 21/03/2012 Les critiques & échangesDiscussions et débats sur la série
dclm_baseline
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Blockchain and cryptocurrency innovator, DigitalX (ASX:DCC), has been appointed corporate advisor for the initial coin offerings (ICOs) of Shivom and Bankorus — both finalists in the Global Blockchain Competition. Bankorus, which is registered with FIRA and SEC, is the world’s first private wealth management platform for high net worth investors powered by artificial intelligence (AI) and built on the blockchain. The Bankorus team built the first robo-advisor in China, now servicing more than 200,000 high net worth clients (HNW – that is, clients with over US$30 billion in assets). Shivom, on the other hand, aims to become the largest genomic data-hub platform in the world. Shivom token holders own their genomic data, control the right to access it, and receive rewards if they choose to share it. DCC CEO, Leigh Travers, said: “Shivom’s medical genomic ecosystem will offer an open web-marketplace for contributors and health providers to add their apps and services, alongside genomic data analytics and personalized medicine.” Travers continued: “DigitalX continues to strengthen its reputation for ICO advisory services and is now working with the world’s most promising blockchain companies as they raise capital to deliver their vision.” The global cryptocurrency market is now worth $500 billion. It’s dwarfed by the high-net-worth market, which is estimated to be worth more than $60 trillion. “Demand for high quality ICOs is growing in 2018 and DigitalX is pleased to be working with companies that already have an established global market for their technology,” said Travers. Both Bankorus and Shivom are at a pre-ICO stage — DCC will provide technical expertise, marketing and promotion services, as well as introductions to its expansive global network. A prospectus for these companies will be made available when the securities are offered and those who wish to receive the prospectus or acquire the securities must complete the application form on the respective companies’ websites. For its work with Bankorus, DCC will be paid in a mix of cryptocurrency (Bitcoin/Ether) and native (BKT) tokens in the project. The company will update the market on the outcome. For services rendered to date, DCC has received US$500,000 in Ether and will receive US$1 million in native (OMX) tokens in the Shivom project. DCC will roadshow both Bankorus and Shivom to its Australian network this week. Due to strong demand, DCC has organised a conference in Perth, Sydney and Melbourne, in addition to one-on-one meetings with potential buyers and partners. Last week, DCC reported record net profits of US$8 for the six months to 31 December, 2017, cementing its position as a pivotal global figure in the blockchain, crypto and ICO advisory space. However, it’s worth noting that DCC is speculative at this stage and therefore investors should take all publicly available information into account and seek professional financial advice.
mini_pile
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Melissa's Cuisine: Peanut Butter Oreo Popcorn Wednesday, January 15, 2014 Peanut Butter Oreo Popcorn Popcorn with a peanut butter and white chocolate coating.  And Oreos.  What's not to love? Melissa's Cuisine: Peanut Butter Oreo Popcorn I am a big snacker. What can I say? I just love food :-) The worst part though, is when I get in a snacking mood, I want to eat everything. Everything.  Maybe that's why this baby weight is still hanging on... One of  my favorite snacks has always been popcorn.  I'm a sucker for a bag of freshly popped buttery popcorn, but I also love the air popped stuff.  We have a variety of flavors that we use on our popcorn.  Even homemade flavors like apple cinnamon! I haven't always been a fan of Oreos, but when I was pregnant I craved them.  I remember telling a friend how I ate an entire sleeve in one sitting (a big deal for me!) and he laughed and said he could eat a whole package!  Apparently everyone loves Oreos. Then I saw this idea combining popcorn, peanut butter, and Oreos.  It was a pregnant snacker's dream come true!  I still love in now.  In fact, I'm off to make a batch...and put on my stretchy pants... Melissa's Cuisine: Peanut Butter Oreo Popcorn Peanut Butter Oreo Popcorn 1 bag microwave popcorn 8 ounces almond bark (or white chocolate chips) 1/4 cup peanut butter 16 Oreos, coarsely chopped 1.  Pop popcorn according to directions on the package. 2.  Pour the popcorn into a large bowl and remove all the unpopped kernels. 3.  Place the almond bark in a microwave safe bowl and microwave for 1 minute.  Stir and add the peanut butter. 4.  Microwave in 30 second increments, stirring each time, until the chocolate mixture is smooth. 5.  Pour the peanut butter mixture over the popcorn and stir.  Add the Oreo pieces and stir again. 6.  Pour the popcorn onto a baking sheet lined with waxed paper.  Allow the chocolate to cool until set. Store in an airtight container.  This popcorn is best eaten the day it is made. Source: Crazy for Crust 1. That looks so good. I wouldn't trust myself to ever stop eating it though! 2. Oh my goodness that looks wonderful! :D Mmmm I have to give this a try! 3. This looks absolutely delicious and dangerous at the same time. In other words, I can't wait to make it. Thanks for sharing your recipe! 4. Thanks for bringing this fun snack to Marvelous Monday! Pinned! 5. I bet I could become addicted to this popcorn! :) Visiting from the Pin It Thursday party at Sweet Bella Roos! Shelley @ PaperCharm 7. I have definitely impressed my professor who had a lot of positive feedback for my reflective essay paper writer. We deliver quality academic papers exactly when you need them and before the expected deadline. 01 10 11 12 Blogging tips
dclm_baseline
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urbaniak.org home home | photos | photography | diving | resources | info | webmail | stats | tools Step-by-step directions for driving My Favourite Car These days most modern cars are equipped with a GPS unit which makes life so much easier. If you have such a device then enter into it my address which you can find on Contact page, and follow the instructions. But not all of us are lucky (actually some call it a curse) and have one of those life saving devices. For those of you I've prepared instructions below. As I cannot provide a detailed directions from each and every possible start location, I have chosen Zurich Airport as a starting point. You can easily change the start address by following the link under the map below to Google Maps site and then choosing different start address and getting new directions. Below you'll find a Google Map with the graphical representation of the route. For detailed step-by-step instructions follow the link below the map to Google Maps site. I've chosen the route that follows A1 motorway via Nordring, then A4 Westring and finally through the Uetliberg Tunnel to A3 Motorway. Just follow signs towards Chur. Once on A3 take Adliswil exit and follow instructions from Google Maps. Once you reach Isengrundstrasse, you should be able to find one of those Blue Zone parking spots to park your car. It seems like a long way round the Zurich City but trust me, it's just as fast or even faster then driving through the city center. Major road works are everywhere (including every possible route due south) and it's a mess. Default route from Google Maps will take you through the City center, your choice! But don't say you haven't been warned :-) BTW, you can always take Public Transport. It's easy and sometimes much faster then driving. View Larger Map valid XHTML 1.0! valid CSS! Spread Firefox Affiliate Button
dclm_baseline
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5 Facets of an Effective Facilitation Experience On August 13, 2014, in Insights, by Phillip A. Jones facilitationThe appointment of a facilitator is a key decision of stakeholders and can make or break a gathering. Facilitation is an art and a science, and a good facilitator is unobtrusive, informed and has command of the conversation. A facilitator is often engaged when the outcomes are important, sensitive and there is usually a degree of risk is involved, especially on the part of the stakeholders who are seeking a particular outcome. There is often a considerable investment of energy, reputation, governance and resources by the participants, and this needs to be respected and acknowledged. A degree of trust in the capabilities of a facilitator by the group is also required, as they are the ones who will shepherd the participants towards an outcome, and are given delegated authority (sometimes overt, sometimes not) to enable that to happen. With the right preparation and experience, a facilitator will guide the participants to a positive, effective and harmonious outcome. The following are some of the key factors I ensure are in good shape when preparing for a facilitation. 1. Explicit Understanding of the Outcomes There are always overt goals for the session, and most usually a sub-text to the relationships, organisation and event itself. You need to have a conversation with the organisers that ensures you are across exactly what they want to achieve, the drivers that made the event essential, and any sensitivities around the issues and personalities. You are also need an explicit understanding of what the client wants you do, including things like documenting the event, key points / messages to make, liaison with participants and post event activities. The basics like venue, timing, budget and timelines & deliverables should also be spelled out. 2. Knowing the Culture of the Group + Workplace One of the gifts of a good facilitator is to be something of a chameleon in order to adapt to the idiom of the group and establish rapport fast. To do that you need to research plenty about the group, its activities, history, aspirations, issues and key players. You can’t know enough about your client and the organisation that’s hosting the event. This also applies to the sector and professional culture generally of the client, understand the drivers and current issues! You’ll need to think on your feet during session, so you’ll need to be up to speed. If there are opportunities to meet participants or attend events hosted by them, then take them up, it will help you get a read on the culture, their  professional language and you won’t be walking into a ‘cold’ room on the day. 3. Research the Participants Continuing your research into the group, the next level of detail is the actual participants. A solid briefing is vital so you know something about everyone in the room (some Googling and LinkedIn may be helpful here), who may be champions for the session goals, who may be challenging them, who needs to be teased out,and who you may need to steer so they don’t dominate the discussion. Some pre-event cultivation is often necessary to establish some rapport with key players to help prepare the ground for the event favourably. I also like to make myself available before the event to meet participants or discuss the event via email if they wish. 4. Establish Your Credentials Without authority, a facilitator is just a glorified MC. You need to be able to own the room, the discussion and guide the conversation where it needs to go, and if necessary intervene to keep things on track. A formal introduction before the event by the organisers is essential, virtually is fine to help establish your credentials. Ensure your website/blog and LinkedIn are all tip-top as its the first thing they’ll look up! It may be necessary to provide the organisers with bio notes etc, and include reference to similar organisations or events you’ve worked on to reinforce your expertise and understanding of their sector. On the day a proper introduction by the host is also necessary and a spelling -out of the ground rules of discussion and the purpose + outcomes to ensure a collective buy-in of your role and the goals of the session. 5. Venue and Environment The physical space is another key element that needs to support the experience in a positive way. Beyond the aesthetics, the layout of the chairs, where people stand and sit, the usual of AV, all impact on the engagement of the participants and conversation flow. You should also consider your eye line and where you’ll move about to ensure even engagement. In short, the space chosen and its layout should be designed to suit the purpose of the gathering, not be just another room! In situations with a need to emphasis equality and avoid dominance by one or more participants, a circle is an effective means to send that signal and enables the facilitator to manage the group with authority. Tagged with:
dclm_baseline
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Q: Processing data from file in awk I have a file as follows (-0.548,15.994) (1.008,8.91) (-0.19,4.594) (-0.99,9.99) I used $ awk '{ mul = $1*$2; print mul }' input.txt > output.txt But all the values of output.txt file are 0s. Can any one tell me where I am wrong A: shellter beat me be a few seconds with a better alternative, but here goes: sed 's/[^0-9,\.-]*//g' input.txt | awk '{split($1,x,","); mul=x[1]*x[2]; print mul}' > output.txt
mini_pile
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Chief Machinery Technician Shawn Barnes, son of long time Mount Carmel residents Judith and Charles Barnes, was promoted to Chief Warrant Officer, Naval Engineering specialty, in the U.S. Coast Guard. Barnes accepted his commission on May 10 onboard his current unity the Barque Eagle, America's Tall Ship, in New London, Conn. In his 16th year of military service, Barnes, along with his wife, Jana, and son, Seth, will be transferring to the Coast Guard Cutter Reliance, a 210-foot medium endurance cutter home ported out of Kittery, Maine, to serve as the main propulsion assistant.
dclm_baseline
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THE MIAMI TIMES—“The People.” PAGE 14 CARDS -- MEMORIALS CARD OF THANKS The family of the late MR. LOMB DIPPONS take this method of thanking their many friends and neighbors who were so kind during their recent bereavement. Special thanks to Friendship Baptist Church, Rev. Burney, pastor. Thanks to the many friends who sent cards, telegrams, flowers and donated cars. They especially wish to thank the tenants of 1240 NW. sth Ave., and neighbors for their generous donations. Mary Dinkins, wife, Odessa Polle, daughter Mary L. Moss, grand daughter Tony A. Moss, great grandson CARD OF THANKS We the family of the late MRS. VIOLA McKEEVER of Vidalia, Ga., who passed on Thursday, Oct. 18, 1056 in Jacksonville, Fla., wish to thank the many friends and members of St. John Baptist Church for the telegrams, flowers and cards of condolence. We wish to express our deepest appreciation for what you have done for us in our sad hour of bereavement. May God bless each and every one, and do accept our prayers in all respects. We loved her but God loved her best. Deacon Harvey McKiever and Family (formerly of Miami) CARD OF THANKS I wish to express my sincere thanks to my and friends that were so nice to me during my operation at the Veteran’s Hospital in Coral Gables. Thanks for the money, get well cards that I received, your kindness shall never be forgotten. Many thanks to Mrs. Nowland of 146 Oak Avenue for the beautiful flowers that she brought me. Again I say many thanks, your kindness shall never be forgotten. Robert A. Munnings CARD OF THANKS To the beauticians and all of my wonderful friends, I take this method to • express my sincere thank you for the wonderful ex pressions of sympathy expended to me during my recent bereave ment in the loss of my mother. I wish to especially thank Mrs. Dorothy Sanford of The Miami Times for her thoughtfulness and Lemmone Ivy. May God shower his richest blessings upon each of you. With humble gratitude Mary Wilson CARD OF THANKS The family of the late, CHARLES STORR, JR. ' sincerely wish to thank our many relatives and neighbors; our pas tor, Rev. S. A. Thomas and mem bers of Mt. Sinai Baptist Church and the Range Funeral Home and family for kindnesses during our bereavement. Also thanks to each one for cards, letters, floral pieces telegrams and tokens of sympathy. Mr. and Mrs. Charles Storr, Sr. and Family CARD OF THANKS The family of the late REBA STORR who died Sunday, Sept. 16, 1956 wish to thank their many friends for their kindness during their be reavement, Also thanks to Rev. T. C. Kelly of St. Paul AME Church and Bain’s Funeral Home for courteous service. Mrs. Henrietta Burrows, grandmother IN MEMORIAM In sad but loving memory of my dear Aunt. MRS. JESTINA MAJOR who departed this life Oct. 31, 1951. May her soul rest in peace and light perpetual shine upon her. Mrs. B. Hamilton Dunwoody, niece SATURDAY, NOVEMBER 3, 1956 CARD OF THANKS ■' ‘ ■' - *&%*■*]& r ' wlw ‘M I -K) JGm, „ w mm , , ’|r 4 J* .. *. HELEN HALL GOODINGS Friends of the late Mrs. Helen Hall Goodings wish to thank all who showed kindness during her illness and passing. Special thanks to Rev. Reddick and Richardson. Funeral Home. Mrs. Goodings passed on October 18, 1956. May she rest in peace and light perpetual shine upon her. A Dear Friend IN MEMORIAM In Memory of WmmsmMaW: VH I -‘.Jllßßl'll ...!<&■ » wf 'I " *r -b- ■■ - fi iillll • «. Si sasSfiSSs; MR. LEDGER CHANDLER who passed away Oct. 31, 1955. Gone but not forgotten, we love you Ledger dear but God loved you best. Mannie Chandler, wife James Chandler, brother Alfred Chandler, brother Pearl Nyles, sister IN MEMORIAM In sad but loving memory of JAMES (PETE) DEVEAUX who passed away on Oct. 23, 1955. There’s an open gate At the end of the road Through which each must go alone And there is a light we cannot see Our Father claims his own. Louise DeVeaux, mother Hazel DeVeaux, wife Mildred Albertine, Sandra Elaine, Ann Louise, daughters Mildred DeVeaux, sister IN MEMORIAM In memory of my dear husband Olila W. MR. HILTON FOSTER who passed into the great beyond on Nov. 6th 1965. He’s gone but not forgotten. May he rest in peace and may light perpetual shine upon him. Mrs. Dora Foster, wife And The Family IN MEMORIAM In loving memory of our dear father REGINALD JOHNSON who departed this life Oct. 31, 1951. May he rest in peace and may light perpetual shine upon him. Mrs. Vera A. Wilson, daughter of Mr. Reginald Johnson, and Mrs. Alene Butler, daughter of Mrs. Alene Butler, died November 3, 1954. Gone but not forgotten. "O who like thee so calm, so bright, Thou son of man, Thou light of light, O who like thee did ever go, So patient through a world of woe." Mrs. Carolyn Williams, and Family 4819 S.W. 24th Street, Carver Ranches in memory of, Mr. Henry Hart who died Oct. 30, 1954. Sleep on and take your rest. I loved you, but God loved you best. You will never be forgotten in my heart. IRENE PEA THS - CUi w- b - C *. Mr. James Z. Pedican of 1455 NW 5th Place, who succumbed on Saturday, Oct. 27, will be held on Saturday, Nov. 3, at 2 p.m. from St. Mary’s W-M. Church, NW 5th Court. Mr. Pedican is survived by a wife, Araminta, 2 daughters, 2 sons, a mother, 3 brothers, 6 sisters, 1 aunt, 1 uncle, 1 daughter-in-law, 1 son-in-law, 4 grandchildren and a host of other relatives and friends. Francis Funeral Home is in charge of funeral arrangements, with internment in Lincoln Memorial Park cemetery. Dr. Charles Johnson Fisk. Dead at 63 LOUISVILLE, Ky Dr. Chas. S. Johnson, president of Fisk University, died here of a heart attack Saturday night. The internationally known educator, sociologist, and author was stricken in Union Station and pronounced dead on arrival at Louisville’s General Hospital. Dr. Johnson, who was 63, had left the train to purchase a newspaper and was returning to his car when he collapsed. He was en route to New York City from Nashville, Tenn., to attend a meeting of the Fisk trustee board. Members of the family said he was in apparent good health when he left Nashville. He had no previous history of heart trouble. Funeral services were held Wednesday in the Fisk University Chapel, in Nashville, with the Rev. William J. Faulkner of Chicago, former dean of the chapel at the university, Dr. Thomas Elsa Jones, former Fisk president, Dr. Fred L. Brownlee, former provost, and Dr. William Lloyd Imes, chapel dean, officiating. Dr. Johnson was elected president of Fisk in 1946, the first Negro to serve the noted institution in the capacity. He had been associated with Fisk since 1928 as director of the Social Science Department and professor of sociology. As president of Fisk, Dr. Johnson brought the university to a position of national and international eminence. This was his central interest in life. He was the author of 18 books and more than 70 articles. Many in sad but loving memory of our dear mother, MRS. CHARLOTTE JOHNSON who departed from us Nov. 4, 1929. Toil on and in thy toil rejoice For toil come rest for exile home Soon shalt thou hear the bridegroom’s voice The midnight peal behold I come. Sleep on and take your rest. The Family FOR THE VERY BEST IN FUNERAL ARRANGEMENTS WITHIN YOUR BUDGET BALM'S FUNERAL HOME 3661 GRAND AVENUE 24-HOUR AMBULANCE SERVICE Everything in Funeral Arrangements M. S. ALLEN FUNERAL HOME IN ITS NEW LOCATION 1744 N.W. 3rd Ave. Phone FR 1-8343, Miami In Homestead, Call 1933 The Price Is a Matter of Your own Desire 24-Hour Ambulance Service YVONNE MAJOR, LICENSED EMBALMER MILDRED S. ALLEN, GENERAL MANAGER 18, Funeral Home (Established 1926) Dignified, Personal, Courteous Service Funerals Within Range of Each Budget INSTANT AMBULANCE SERVICE 315 N.W. 15th Street Phone FR 3-1440 “A Living Service for the Living” RANGE FUNERAL HOME OSCAR AND ATHALIE RANGE, OWNERS PHONE PL 1-1331 Instant, Efficient Ambulance Service Oscar Range. Licensed Embalmer - Funeral Director 6705 N W. 15th Avenue Books and articles have also been written about him. Dr. Johnson served his nation in many capacities. He was a member of the international commission of the League of Nations to investigate slavery and forced labor in Liberia. After World War II, he was appointed to the commission charged with reorganization. izing the educational system of Japan along democratic lines. He was American delegate to the United Nations Educational, scientific and Cultural Organization, and last year was elected president of the UNESCO conference on race and race relations. He also served on several presidential commissions. He was also a director of the Julius Rosenwald Fund, a past president of the Southern Sociological Society, a member of the executive committee of the American Sociological Society, to name but a few of the many posts of high responsibility which he held. President Johnson was awarded honorary doctorates by Virginia Union University, his alma mater, Howard University, Harvard University, the University of Glasgow, Scotland and Lincoln University of Pennsylvania. He is survived by Marie Antoinette Burgeitte Johnson, his wife, three sons, one daughter, three sisters and five grandchildren. CARD OF THANKS The family of the late, Mrs. NERVAN WILKERSON, expresses its thanks and appreciation for all the many kind gifts extended during its hours of bereavement. Thanks for your cards, letters, telegrams, flowers and all other tokens of sympathy. Again, thanks to everyone for everything. Ernest Wilkerson, husband, Deloris Francis, niece, and Family.
common_corpus
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Graphene Wrinkles Enable Spatially Defined Chemistry. This paper reports a scalable approach to achieve spatially selective graphene functionalization using multiscale wrinkles. Graphene wrinkles were formed by relieving the strain in thermoplastic polystyrene substrates conformally coated with fluoropolymer and graphene skin layers. Chemical reactivity of a fluorination process could be tuned by changing the local curvature of the graphene nanostructures. Patterned areas of graphene nanowrinkles and crumples followed by a single-process plasma reaction resulted in substrates with regions having different fluorination levels. Notably, conductivity of the functionalized graphene nanostructures could be locally tuned as a function of feature size without affecting the mechanical properties.
mini_pile
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yangın tüpü baca temizliği davlumbaz söndürme sistemi Polonezköy Hakkında Cumartesi 20 Nis 2019 Polonezköy Hakkında Polonezköy is a famous Polak village in Beykoz district of İstanbul. It is 20 km far from The Black Sea coast and 15 km far from The Bosphorus coast. The early name of Polonezköy is Adampol. Polonezköy was founded in 1842 by Prens Adam Czartoryski who was the government head during Poland revolt in 1830 and later was the political leader of Polish exiling. The name of the village was created from it’s founder’s name Adam as Adamköy. Land of the village was organised as a farm by Lazarist monks who were directing Saint Benoit French High School. Paris was the center of the political immigration of the Polish at those times. Aim of Prens Adam Czartoryski was to found the second policy center in the borders of The Ottoman State. Fort his reason he sent Michal Czajkowski as his representative to The Ottoman State. Czajkowski who received the name of Mehmed Sadık Pasha by accepting Islam in 1850 after coming to İstanbul bought a forestry area. 220 people resided in the village where only 12 people resided in the beginning. Polonezköy residents were accepted to Turkish citizenship in 1938. Polonezköy residents had the right for land title over the field they used. Polonezköy has turned into a holiday village from an agriculture village with it’s transport opportunities, geographical position and it’s beatuful landscape. Lands of Polonezköy belong to village residents or rich and famous people who arrive in Polonezköy for rest. Young people immigrated abroad in the 1980s started turning back to Polonezköy with development of the village and economic conditions and started running pension, restaurant and cafes. Today approximately 1000 people live in Polonezköy. 40 people among these residents speak smooth dialect. Polonezköy festivity is held every year in Polonezköy emphasising bonds between Polonezköy and Poland.  The people of Polonezköy invite folklore groups participating to this festivity with their own financial potential. Places worth seeing are: Polonezköy that is prefered for picnic. 1. Zofia Rizi Anı House- inner side- old and new photos, books and documents belongs to Ryzy Family. 2. Czestochova Mother Mary Church 3. Polonezköy cemetary where you can see graves of Ludwika Sniadecka whom Poland national poet Juliusz Slowacki fell in love with and other 92 historical graves restorated by Poland Republic National War and Martyrdom Council. Developed: VKC Bilişim
dclm_baseline
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There are a lot of ways to protect yourself from having your credit card information stolen. My personal protection method is to not have a credit card or debit card. I usually barter with chickens, eggs, and magic beans. Come on, we all have a credit or debit card and now those cards and the information they contain are even more at risk. And you thought you were going to be able to get a good night's sleep tonight? Not so fast my friend. Many of us are aware of the "jiggle method" when it comes to sliding your card into a gas pump, ATM, or dancer's G-string. By the way, you can't legally use the jiggle method on that last one. The jiggle method works like this. Before you slide your card simply grasp the card reader with your fingers and give it a tug. If it jiggles, even a little bit, my advice would be move on to another pump or ATM and notify the proprietor of the place of business. Yes, these kinds of skimmers have been found in Louisiana. Now comes word that new evil-doer technology allows the bad guys to insert a card reader that isn't so bulky. These new skimmers are called "shimmers" and they are so small the untrained eye could never spot one. The "shimmer" slides inside the real card reader and you'll never even know you've been scammed. It's actually a strip about the same size as the magnetic strip on your credit card. What can you do to protect yourself? Authorities suggest you monitor your bank account on a daily basis. Be on the look out for unauthorized purchases and make sure you hide the keyboard with your other hand when you punch in your PIN. Some of these identity thieves plant cameras around transaction sites to pick up your PIN via camera. Of course, another way to protect yourself would be to just remain poor. I hate it when the thieves send me a personal message of condolence about the balance in my bank account.
dclm_baseline
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August Mini Kit Challenge hosted by Jen. Top journaling: My brother has a 40-acre country property. He has a strong sense of stewardship for the land, and has worked hard all his life for the protection of the environment and wildlife. He added a huge pond and his property is officially a designated as Woodlots and Wetlands area, approved by the Minister of Natural Resources. Bottom journaling: We love spending time out here. It is so peaceful and the only sounds you hear are the birds, crickets and bullfrogs. I ran out of room for the text, lol. The lower right photo is a close up of the turtle rest area in the pond. There's a little ramp for the turtles to climb up and sun themselves. In the pic there's a painted turtle on the platform, but it's hard to see. My brother has dozens and dozens of bird-feeders that he fills daily. They get some beautiful birds that spend the summers, and a few who stay all winter. Kit: 'Slow and Easy' (Pixels by Jen), plus 'Slow and Easy Flairs' (Pixels by Jen) No template. I just stuck things here and there until it felt right.
dclm_baseline
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Production Lines • +5% wealth from all commerce • +5% tariff income from trade agreements As ever-increasing populations demanded more goods it became necessary to explore the principles of mass-production. This led to the development of piecework: the construction of component parts that could be produced quickly and in large quantities. Teams of workers would then assemble these parts into goods. Roman philosopher and writer, Pliny the Elder, tells of shops dedicated to the production of individual chandelier parts. There is also evidence to suggest that factory-like production was used in urban areas for the manufacture of pots, building parts and military items. Faction Availability
dclm_baseline
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30-Day Writing Challenge – Interesting, Fun and Creative 30 Day Writing Challenge Planning to follow a 30-day writing challenge? Let us help you. Do You Wish to Write Like a Pro? Do you want your writing to shine and the world to appreciate it? You must be committed to writing to be able to achieve this. But are you afraid of commitment? Following a writing challenge can take you there. You must remember that you cannot produce volumes of great writing overnight. There is no need to make it so intense that one prefers to run away from it. In fact, all you need to do is take baby steps. You must have come across these intense writing challenges that seem like quite an ordeal. But you don’t have to put yourself through that. We can give you a 30-day writing challenge that doesn’t require you to produce 50,000 words a month. Our simple and fun 30-day writing challenge gives you the liberty to write as little or as much as you want. There’s no pressure and no feeling bad about not completing the number of words the challenge requires. Our writing challenge is not about volume, but creativity and creation. It’s not intense, but interesting and fun. It has creative writing exercises, one for each day of the month that you will enjoy doing. It isn’t a task but an activity that will make you fall in love with writing and not run away from it. Without further ado, let’s take a look at our 30-day writing challenge. Day 1 On day 1 of your writing challenge, take us on a written journey to your favorite place. But, wait, here is the challenge. You have to write through the eyes of someone else. Sounds interesting, eh? Write as much or as little as you want. Don’t worry if you don’t want to write too much. After all, it is just the first day of your writing challenge. Day 2 Think about three of your favorite people. Now create a protagonist using the laugh and hair of the first person, the personality of the second person and the face and mannerism of the third person. You have a protagonist. Now start writing about him or her. You can add more traits to your character. You don’t have to write a big story. How about just the first 5 minutes of their day? Day 3 Remember your protagonist? Send them to their grumpy aunt’s place for a day. They have reached her house. Write in detail about the scene of their arrival. Add as much detail as you want. Day 4 Oh, your protagonist just turned into a statue. On day 4 of your writing challenge, write about their thoughts and feelings now that they are a statue. Write about what they see and what they think should be different from its current state. Day 5 Your protagonist drank a potion that has turned them into a superhero. They have some superpowers. Write about these superpowers? What can they do with these superpowers? Day 6 Okay, enough about the protagonist. Think about the food you love the most. Have a dish in mind? No, you don’t have to write about how amazing it is. For a change, write about it and make it sound as disgusting as you can. Day 7 of your writing challenge Day 7 What’s your favorite movie? Change its ending. Introduce a new character that ruins the ending. You can also do the same with a book you really like. Trust us, your love for the movie or book will not be affected and you will have something interesting to write about instead of just sitting there and thinking about what you should write about today. Day 8 Do you have a favorite quote? Write it down in your journal and describe in great detail why you like it. If the quote applies to any life incidents, write about that too. Also write something about a person whom you really wish had read and followed this quote. Day 9 Talk about your family. How many members do you have? What makes each family member different? Does anyone of them have a story that you are truly inspired by? Do you wish someone was a little different? Day 10 Do you have any fears? Write about them in detail. While you are at it, also add what you like and dislike about yourself. Is there something you feel strongly about or would change? Write about it all on day 10 of your 30-day writing challenge. Day 11 of your writing challenge Day 11 Do you have a favorite story? Take its first line and write a new story based on this line. You are at liberty to mold the story as you want. Day 12 What is it that makes you laugh? Think about five things and write about them. Do you make others laugh? What are the traits that others like in you? Write all about it on day 12 of your 30-day writing challenge. Day 13 Everyone has someone they look up to. Who is your inspiration? What is it that you like about them the most? Which of their traits do you admire and what would you do differently if you were in their place? Pen it all down. Day 14 Do you like sports? What’s your favorite? What do you like the most about it and when did you become interested in it? Are there any other sports that you wish you were good at? Do you wish to play some sport professionally? Dedicate day 14 of your writing challenge to sports. Day 15 Are you currently watching any television series? What is it about? What do you really like about it? If you could play a character in it, which one would you choose? Also, write about your favorite actor and why you like them the most? Day 16 of your writing challenge Day 16 Think about something someone said that hurt you a lot. It can be something recent or something that happened in the past. How did you react? Would you do something differently if the same thing happens again? Write about how you have changed as a person over the years. Day 17 Do you have a bucket list? Why not tick one item off it by writing about it? Want to go to Paris? Write as if you recently went there. Similarly, you can write about any item on your bucket list and dedicate day 17 of your writing challenge to it. Day 18 Do you have any goals? Write about where you see yourself in the next five or ten years. Explain in detail what you will be doing then and how your life would be different.   Day 19 Everyone has their strengths and weaknesses. Write about your strengths and weaknesses from your own perspective and then from the perspective of someone else. Day 20 Do you believe that zodiac signs actually have an impact on your personality? What is your zodiac sign? Do you think it has an effect on your life? Write about how zodiac signs impact you on day 20. Day 21 Imagine that you were recently hired as a writer in a big editorial firm. Describe your first day at work. Let your imagination and creativity flow. Write about how you would win everyone over. Who would be your boss and friends? Day 22 You just met your celebrity crush. Who is it? What to do you want to say to them? Plan a day out with them and write everything that you would like to do with them on this day. Be as imaginative as you want. Day 23 of your writing challenge Day 23 Think about your ideal man or woman. What traits do you think they should have? How should they look physically and what characteristics should they have? Which of their features or traits do you admire and want to have? Day 24 What is your idea about the perfect summer? Where do you want to go? Who do you want to have around? What would it be like and what activities would you do? Day 25 It’s the holiday season. What comes to your mind when you think about Christmas and the new year? Who do you want to spend this time with and what would you do? Write about your perfect holidays and all the things included in it. Day 26 Did you go shopping recently? Is there something that caught your attention and you really wanted to buy? What was this thing? Why didn’t you buy it? Write all about this thing and why you wanted it so badly. Day 27 What’s your greatest fear? It can be a person, place, thing, animal or anything. Why are you afraid of it? What if you have to face it? What strengths do you need to face it? What will you do in such a case? Day 28 of your writing challenge Day 28 Talk about a person’s weird habit. What is this habit and why do you find it weird? What would you like to change in this person? Will you adopt this habit of theirs and how will you deal with it? Day 29 Everyone has some guilty pleasures. What are yours? Write about all the things you can think of and spend day 29 of your writing challenge doing it. Day 30 This is the last day of the writing challenge. Write about how you felt about the writing challenge. Did you like this writing challenge? Did it change you in any way? Congratulations! You’ve reached the end of the 30-day writing challenge. We hope it was fun and interesting. Let us know if you liked it and would recommend it to others.
dclm_baseline
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Thermonuclear explosions on neutron stars Jacob FiskerLLNL Thermonuclear explosions of accreted hydrogen and helium on the surface of neutron stars, which are observed as type I-ray bursts, are the most frequent type of explosion in the galaxy and the third most energetic after supernovae and classical novae. They have been observed almost continuously since their discovery in 1976. However, during the past decade a new class of neutron star bursts, called superbursts, has been identified using BeppoSAX and RXTE data. According to theory superbursts are caused by deep and massive explosions of the carbon accumulated in the X-ray burst ashes. The problem is that detailed numerical X-ray burst simulations do not produce the required amount of carbon to satisfy this theory. In the talk, I present global studies of the behavior of the neutron star that theoretically restrict the reaction rate uncertainty based on astronomical observations. If this rate were just right, it would lead to copious generation of carbon. In addition, I discuss numerical models of the period following the superburst where X-ray bursts are quenched by the decaying thermal flux and massive amounts of carbon can be generated.
mini_pile
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Q: Oracle Equivalent for IIF in Access SQL? In access I used to use IIF function in SQL queries Select iif(X>=0,'Positive','Negative') from TableName; Is there any equivalent for that in Oracle ? A: Use a CASE select case when x >= 0 then 'Positive' else 'Negative' end as sign from tablename;
mini_pile
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PHOTO: Counting Lincoln's steps -A A +A  Hodgenville Elementary School students attended the “Walk Through Lincoln’s Life” program Thursday at Abraham Lincoln Birthplace National Historic Park. Gabriel Wright, a student in David Edwards’ first grade class and his assistant, Mary Gomer, counted the steps leading to the Memorial Building. Renew Current or Past Subscription / Register for Online Subscription Newspaper Acct. ID: Street Address: (exactly as it appears on the label) New Subscription/30 Day Free Trial Account ZIP Code: Create a limited access account. 40 Shawnee Drive, Hodgenville, KY 42748
dclm_baseline
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If there's anything more difficult than a clogged nose on a chilly winter morning, it's got to be a blocked Subaru Gl air filter. If the air filter of your Subaru Gl fails, dust, dirt, and debris can quickly enter into your engine, badly affecting not only the combustion process but also resulting in wear and tear to its parts. It's important that you replace your broken part right away to keep your valuable vehicle from malfunctioning. Today, you can easily pick froman array of air filters for your Subaru Gl at local and online auto shops, however a few of these products can't match the standards of your ride. So the most realistic move here in replacing the air filter of your Subaru Gl is by choosing the one that specifically fits into your engine; this way, you won't have to worry about installation. Choose a Subaru Gl air filter that's constructed from premium-class materials that features versatility and durability, making it last longer in your ride. You can see far better outcome i.e longer engine life, enhanced fuel economy, and high-class ride performance right after you're done with your Subaru Gl air filter replacement. Here at our site, you can select from our huge selection of budget-friendly air filters made by AFE, Hastings, Pentius, and other dependable manufacturers in the industry. So get our surprising package and place your delivery right away!
dclm_baseline
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Artificial Intelligence for Legal Contract Review Artificial intelligence (AI) is a term more associated with the realm of science fiction than law. Many lawyers have simply turned a blind eye to the impact that AI and machine learning technology are having in a vast array of contemporary industries, from financial services to medicine. There is no reason that law should be any different—after all, a great deal of lawyers’ time is spent on tedious, repetitive tasks that machines are now fully capable of automating. The technology has already permeated the European legal world. 56% of the top 100 UK law firms report they are already using AI or are “very likely” to do so. American lawyers need to take notice of the true commercial potential AI brings to both law firms and in-house teams. The London-based Luminance team is attending ABA TECHSHOW for the first time this year and, in the wake of a successful trip to LegalTech last month, is excited to speak to more American lawyers about the potential of AI to vastly improve their efficiency. Luminance harnesses the power of artificial intelligence to read and understand complex legal documentation. Drawing on R&D at Cambridge University, Luminance was founded by a combination of lawyers, M&A experts, and mathematicians. World-leading UK law firm Slaughter and May have partnered with Luminance to develop, test, and pilot the software, using their extensive deal-making experience and deep understanding of due diligence. By clustering and comparing thousands of documents simultaneously, Luminance vastly improves the efficiency of due diligence. Our clients have found that their lawyers cut their time spent on contract review in half, freeing them for higher-value work. To date, Luminance has been used on dozens of live transactions—from South Africa to Norway—since its launch in late 2016. This is a guest post from Luminance. Visit them at ABA TECHSHOW in the EXPO Hall at Booth #804 where the team will be giving product demonstrations. CEO Emily Foges will also be presenting on Thursday, 3/16 from 3pm-4pm. Learn more about the Conference. Check Also speech bubbles coming out of colored pencils Effective Communication in a Screen-Dominated World Knowing how to communicate quickly and effectively in a screen-dominated environment is crucial to communicating convincingly.
dclm_baseline
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Toxicology case: Jatropha multifida toxicosis in a dog Toxicology case: Jatropha multifida toxicosis in a dog A 4-year old 50-lb (22.7-kg) neutered male standard poodle was presented to an emergency clinic for evaluation of severe vomiting, anorexia, and lethargy that had progressively worsened over the preceding two days. The owner observed that the initial vomitus contained between 10 to 20 intact as well as chewed sections of an unknown type of large seed. Initial conservative treatment at the pet's regular veterinarian included famotidine (20 mg orally every 24 hours), metronidazole (250 mg orally every 24 hours), sucralfate (1 g orally every 12 hours), and a bland diet. After eight hours, these treatments had failed to control the clinical signs, so the pet was referred to an emergency clinic for further diagnostic testing and treatment. Upon arrival to the emergency clinic, the dog was lethargic and moderately dehydrated (estimated 7% to 8%). Jaundice was also noted by the emergency clinician. The jaundice as well as the previously noted emesis of an unknown seed led to a suspicion of sago palm (Cycas revoluta) toxicosis. While the dog was being treated, the owner was sent home to see if the dog could have had access to a sago palm and, if so, if the seeds matched the ones it had vomited earlier. 1 & 2: The dog’s owner took photos of the suspicious seeds and tree, later confirmed as Jatropha multifida. [Editors' note: Whoops! These are actually photos of Jatropha podagrica, not Jatropha multifida. The two species look a lot alike, and both have similar toxicology profiles. In this case, the owner was found to have both species of Jatropha in his yard. Jatropha multifida seeds were determined to be the mostly likely cause of the toxicosis in this dog.] The owner did not find a sago palm on his property but did find several seeds in the yard that matched the ones found in the vomitus. Upon the advice of the emergency clinician, the owner contacted the ASPCA Animal Poison Control Center (APCC) for help identifying the seed and making recommendations for treatment. The owner provided pictures of the suspected tree (Figures 1 & 2), which allowed the identification and confirmation of Jatropha multifida (commonly known as physic nut, coral plant, or coral bush) as the source of the seeds.
dclm_baseline
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Kulak Invited to NHL Scouting Combine The Vancouver Giants are pleased to announce that defenceman Brett Kulak has received an invitation to attend the 2012 NHL Scouting Combine. He is the highest-ranked Giant in NHL Central Scoutings year-end list, coming in at 55th amongst North American skaters. Kulak played in all 72 regular season games this season, tallying 9 goals, 15 assists, and a team-best +29. He then registered 4 assists in 6 playoff games. The top 105 draft-eligible players from North America and Europe will attend the Scouting Combine from May 28 to June 2 in Toronto, going through a vigorous round of physical, medical and psychological tests that could determine where they are chosen.The combine is also an opportunity for teams to meet and interview prospects. Testing will be conducted June 1-2 at the Toronto International Centre. 10 forwards, 10 defensemen and 2 goalies from the Western Hockey League will attend the 2012 NHL Scouting Combine, including rearguard Ryan Murray of the Everett Silvertips, who is the WHL’s highest-ranked player in Central Scouting’s final rankings of North American skaters. The 2012 NHL Draft will take place June 22 & 23 in Pittsburgh, PA. Here’s a list of the WHL players invited to the 2012 NHL Scouting Combine: The Canadian Hockey League (CHL) cares about your privacy. Thank you for your interest in our network of websites, newsletters, and other services. We believe in fully disclosing the methods to which we collect and use your personal information. We also invite you to ask us about our policies or feel free to let us know how we can better serve your privacy concerns.
mini_pile
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Start a new topic Game Ideas and Tweeks Trying to understand why we are only allowed to have 30 friends. Most similar games allow as many as you can handle. As well, Only being able to gift 5 of your neighbors is rediculous. It seems to me, we should be limited to the number of gifts we can recieve, but have the ability to send as many gifts as we have neighbors. If a neighbor has all their allotted gifts for the day, then they simply wouldn’t be able to recieve a gift from you for that day. And why let the bots tip? I think the tips should come from your friends, when they stop by. Limiting the number of friends you’re allowed to have, does not encourage a lot of new player traffic. The game gets boring when you have to rely on random drops from bots or temporary visitors. And let’s talk about communication within the game… Why do we not have our own wall for chat? We only have the ability to chat with others if we join a club. There is no way for people to build great clubs for competitiveness if you can’t chat with other people from other cafes in order to strategize and recruit great friends. Constant tasks? We already have so much to do as it is. Master dishes, send deliveries, (both truck and on line) tournament tasks, throw parties, and cook food for celebrities. The game is entirely too busy. I feel like the tournaments should yield some kind of Cafe Decoration rather then more vouchers, tokens, sauces, etc… Decorating 臘‍♀️ there’s another problem. Everything is soooo expensive and the only way to get real interesting decorations are thru spins. What?! I’ve been spinning till I’m dizzy and “rare” is on point when it comes to describing how often you might land a decoration peice. 廊 I think decoration should be available to buy with either coins or cash, at ANY TIME! My oh my! …… I could go on and on about the things that would improve the game for the players while garnering more profit for the developers, but suggestions are usually ignored by most developers, so I’ll not spend anymore of my time on this. Just wanted to get it off my chest. 路‍♀️ Let’s spend some time on the whole decoration aspect though... Tables, chairs, lamps, dividers, and wall deco are but a small portion of what could be designed for the cafe. Let’s talk about REAL decoration ideas that let your imagination run wild and give players incentive to “spend real money” on the game. How about a garden cafe with shrubbery scenes such as birds in trees or bees on flowers. Or maybe a whole rain Forrest scene. I once saw a restaurant like that. They had tanks with exotic fish and it was like you were walking thru a rain Forrest. Maybe a beach resort cafe with beach floors and wall paper that has a beach front scene. There could be seagull and crab decorations, along with a lifeguard tower and people in bathing suits. Or we could do a park scene with dogs mid air catching a frisbee and picnic baskets full of food. Maybe children playing tag and kids on a playground. We could do Pirates on the ocean or maybe a Tea party scene with flowery tables and chairs. A Tea Hutch and maybe a tea lamp. There could be people sitting around a table having tea. So as you can see, I’ve got tons of ideas. If pictures would help, I’m sure I could find some. By the way, some winter tables, any color, (Red, Pink, Blue) but with ice flakes all over them, would be so nice! 2 people like this idea Great recommendations there. Check out for Assignment help   , Lab Report Writing Services Thanks, dear, In this lockdown, we can easily spend our time via playing games Login to post a comment
dclm_baseline
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DVD Talk Release List Reviews Shop Newsletter Forum DVD Giveaways Blu-Ray Advertise Reviews & Columns International DVDs Video Games Collector Series DVDs Easter Egg Database DVD Talk Radio Feature Articles Anime Talk DVD Stalk DVD Savant High-Def Revolution Silent DVD discussion forum DVD Talk Forum DVD Price Search Customer Service #'s RCE Info DVDTalk Info Review Staff About DVD Talk Newsletter Subscribe Join DVD Talk Forum DVD Talk Feeds Special Offer Search: For: Reviews » DVD Video Reviews » Beatles: The Journey Beatles: The Journey Music Video Distributors // Unrated // June 17, 2003 Review by Holly E. Ordway | posted July 11, 2003 | E-mail the Author Buy from Amazon.com Skip It E - M A I L this review to a friend Printer Friendly The movie The Beatles are certainly a group who are due for a great documentary, so it was with enthusiasm that I approached the DVD/CD set of Beatles: The Journey. I've listened to all their albums and own a number of them, and I wanted to find out more about the individual Beatles and how they became a group, as well as how their group found such amazing success. Since The Journey has a subtitle claiming that it's the story of "The remarkable formation and rise of the world's first supergroup," it seemed like I was going to get what I'd hoped for. What a colossal disappointment. The Journey would be better off with the label "Miscellaneous and badly organized footage of the various Beatles members over a number of years." It's been quite a while since I've felt so badly burned by a promising documentary, but the truth is that The Journey is an incoherent mess that does the Beatles the greatest injustice it could: it makes them boring. There's no clear organization; we jump into clips of the Beatles when they're already famous, with screaming fans a-plenty, followed by more clips of them during television interviews or on the road. So much for documenting their "formation and rise": all we get in that regard is one of the band members' classmates offering a few comments about their school days. No context is given for any of the events depicted, so we don't know where the band is, or where they're going, or when the events are taking place, or why we should care about any of it. Giving further lie to the film's title, the documentary soon shifts away from the Beatles as a group, instead focusing on footage of the individual members of the band in later years, particularly John Lennon's peace messages and later murder, and ending with footage vaguely related to George Harrison's death. Amazingly enough, describing the content in this way actually suggests a clearer structure and pacing than is actually present. There is no overall narrator, and the film jumps from one topic to the next without any warning, except for a few brief, almost-illegible, and obscure title cards, which don't even appear consistently. Some modern-day interviews are sandwiched into the vintage material, but these appear to have been inserted more or less at random, at least insofar as their relevance to the preceding and following material is concerned. Several of the interviewees (who are often not identified) speak at length about George Harrison and how he was or wasn't properly appreciated in the group; we're never given that much detail about any of the other members, and it's never clear why Harrison was singled out here. The choice of material is also rather dubious... or rather, the lack of proper editing of the material is very evident. Many of the interview clips, both vintage and more recent, run far too long, becoming highly tedious, and some are downright pointless: why do we get a long press conference from the wife of the man who shot John Lennon? The worst offense of The Journey isn't its lousy editing or its lack of structure, however: it's that the documentary is singularly uninformative and dull. Hardly any actual information about the band is presented, and the little bit that is, almost seems to have been included by accident. The endless sequences of the Beatles going to one place or another are presented with only some trivial background music; sorry, but I'm not such a Beatles fanatic to be overcome by joy at just (gasp!) seeing images of the Fab Four on my television screen! And to add insult to injury, the film doesn't even feature the great Beatles music I was hoping for. Despite the film's other problems, at the very least, I was looking forward to a great soundtrack, but none of the characteristic Beatles songs appear, just some rather unobtrusive stuff and a couple that I only vaguely recognized. As it happens, I noticed a small statement on the back of the DVD case: "This programme does not contain original Beatles music and is unofficial." Wonderful. Given that the songwriting of McCartney and Lennon was one of the strengths of the Beatles, the absence of any of their original music on the DVD is a big disappointment. The film runs an hour and 20 minutes, though if you watch it, you'll feel that it's at least twice as long. Beatles: The Journey is a two-disc set packaged in a double-wide keepcase; the first disc is a DVD with the documentary film, and the second is a CD with audio-only interviews. The Journey appears for the most part in a 1.33:1 aspect ratio image, though portions of the footage are presented in a letterboxed widescreen aspect ratio. Most of the material showing the Beatles is in black and white, while the modern interviews and the later footage of the individual Beatles members appear in color. The more recent interviews are reasonably satisfactory in terms of image quality, appearing clean and clear, with fairly natural-looking colors. The older footage, however, varies between "bad" and "horrible" in terms of image quality. The prints are beat-up and dirty, with extremely poor contrast making it difficult or impossible to recognize who's who at times. This material is only from the late 1950s at the earliest, so there's no compelling reason why it should look this bad; at the least, some restoration of the material should have been done beforehand. The soundtrack is presented in "PCM" (pulse code modulation) format, at 48k 16b. PCM is a non-lossy recording format, as compared to Dolby Digital and DTS, in which some audio information is lost as a tradeoff for the ability for the track to be compressed to a certain extent on the DVD. In theory, the PCM track should allow for a higher-quality audio than is possible on CD. In practice, the sound quality for The Journey is lousy, and probably would have sounded lousy on any audio format. With no original Beatles music included in the soundtrack anyway, there's nothing that really cries out for a better-than-CD-quality soundtrack anyway, and the interview footage is in such poor condition that the first order of business should have been to clean it up before it was transferred to the DVD. The sound varies between merely mushy and flat to actively garbled or harsh-sounding, depending on the source material. While the unrestored source material didn't detract all that much from the video portion of the film, the same issues on the audio side of things make for a less than enjoyable listening experience. I've considered the documentary to be the main feature of this set, so the second disc can be considered as a "special feature." This second disc is actually an audio CD, "In Their Own Words," and includes about 50 minutes of various interview clips of the Beatles. Unfortunately, the different clips have no introduction to indicate who is speaking or when the interview took place, and no chapter list with that information is provided as an insert. I suppose it's intended for listeners who are intimately familiar with the Beatles and will be able to instantly identify who's talking. Unfortunately, that's not me, and the lack of any context whatsoever robs the CD of any interest it might have otherwise had. The only really worthwhile part of this set is the insert booklet, which is a rather sorry commentary on the set overall. This 32-page booklet offers a brief but interesting history of the Beatles, and a quick look at some of their most famous songs. It throws into sharp relief just how terrible the documentary film is: the booklet shows how much interesting material could have been included in the film, but wasn't. Of course, the booklet itself is very short, so there's not a lot of content in total. (The DVD case also describes the booklet as being in "super colour," which as it turns out is advertising-speak for "mostly black and white with three small color photos." Wait: the text appears on a pale green background, so maybe that's where we get the "super" color.) A few minor text features are included on DVD as well: a biography/history of the Beatles, a discography listing all their albums and song titles (but without dates, unfortunately), and a photo gallery. The menus are straightforward-looking but painfully slow to navigate, with significant lag time on responding to selections. Final thoughts The Journey puzzles me. Considering how interesting the subject is, it's hard to conceive of a more dull and disappointing approach to making a documentary about it. Beatles: The Journey will only be of interest to the most incredibly hard-core fan. By that, I mean someone who already knows every scrap of trivia about the group, and who will be delighted just to see "rare" footage of the Beatles, however dull that footage may be on its own merits. I strongly suspect that this will rule out the vast majority of viewers, however: it certainly doesn't include me. Skip this dud and use the money to pick up a Beatles CD instead. Popular Reviews 1. Blue is the Warmest Color: The Criterion Collection 2. Thunderbolt and Lightfoot (Limited to 3000) 4. The Grandmaster 5. Shawn Michaels: Mr Wrestlemania 6. The Last Days on Mars 7. Horror at 37,000 Feet 8. Married With Children - Season 1 & 2 9. Charlie's Angels: Season 1 10. The Blue Max (Limited to 3000) Special Offers DVD Blowouts Alien [Blu-ray] Buy: $19.99 $9.99 Special Offers Release List Reviews Shop Newsletter Forum DVD Giveaways Blu-Ray Advertise
dclm_baseline
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Breaking News US troops in Syria and allies exchanged fire with pro-Syrian regime forces A convoy of US troops and Syrian Democratic Forces were fired upon in eastern Syria Monday morning as they were traveling through a known checkpoint manned by Syrian pro-regime forces, the US-led coalition reported. No US personnel were injured, according to Col. Myles Caggins, the chief spokesman for Operation Inherent Resolve, who said that the coalition forces returned fire. “Coalition and Syrian Democratic Forces, conducting a routine anti-ISIS security patrol near Tal Al-Zahab, Syria, encountered a checkpoint occupied by pro-Syrian regime forces. After receiving safe passage from the pro-regime forces, the patrol came under small arms fire from individuals in the vicinity of the checkpoint. Coalition troops returned fire in self-defense,” Caggins said in a statement. Helicopter convoy While there were helicopters overhead flying standard convoy escort duty, the coalition did not conduct any airstrikes, Caggins said. The convoy then returned to base. The incident remains under investigation. The US is not yet able to confirm Syrian casualties or that the troops that fired on them were uniformed Syrian military personnel, Caggins said. It is not clear why the shooting began, because convoys have regularly passed through checkpoints with few incidents. The US maintains less than 1,000 troops in Syria currently to fight remnants of ISIS. They are stationed both near the eastern oil fields and at the At Tanf garrison in southeastern Syria. The Syrian state news agency claimed that US forces attacked a checkpoint, killing one and injuring two. A Syrian military source told SANA that “at 9:45 am, a US patrol tried to enter the area where one of our military formations is deployed in Qamishli countryside through Tal al-Zahab checkpoint, and the army personnel at the checkpoint prevented it from passing, therefore, the members of the US patrol opened several rounds of fire.” Source link
dclm_baseline
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George Greene House The George Greene House is a single-family home located at 115 West Sugnet Street in Midland, Michigan. It was listed on the National Register of Historic Places in 1989. History George Greene was a plant engineer at the Dow Chemical Company. In the spring of 1936, he hired Alden B. Dow to design this house. The house was the second of three Dow designed at the edge of the golf course. Construction began in June by the Alden Dow Building Company at a cost of $15,481. The house was completed in 1937. The garage was enlarged in the 1970s. Description The George Greene House is a single-story brick house of 1600 square feet. It is built of two sections: a long rectangular one and a shorter square section, placed at a 45 degree angle to the main section. The entrance to the house is at the junction of the sections, accessed by a short staircase at the opposite end of the building. A long walkway sheltered by a roof overhang connects the stair to the entrance. References Category:National Register of Historic Places in Midland County, Michigan Category:Prairie School architecture Category:Residential buildings completed in 1937 Category:Alden B. Dow buildings Category:Midland, Michigan
mini_pile
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Q: How to transform a CSV column in dataframe to rows I have a dataframe with CSVs in language column Name Language 0 A French,Espanol 1 B Deutsch,English I wish to transform the above dataframe as below Name Language 0 A French 1 A Espanol 2 B Deutsch 3 B English I tried the below code but couldn't accomplish df=df.join(df.pop('Language').str.extractall(',$')[0] .reset_index(level=1,drop=True) .rename('Language')) .reset_index(drop=True) A: pandas.DataFrame.explode should be suited for that task. Combine it with pandas.DataFrame.assign to get the desired column: import pandas as pd df = pd.DataFrame({'Name':['A', 'B'], 'Language': ['French,Espanol', 'Deutsch,English']}) df = df.assign(Language=df['Language'].str.split(',')).explode('Language') # Name Language # 0 A French # 0 A Espanol # 1 B Deutsch # 1 B English
mini_pile
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can ducks eat moldy bread Is it harmful to feed ducks/geese/birds old or moldy bread? August 19, 2017 – 07:26 am Feeding Ducks | The Fresh Loaf Yes. Feeding old and moldy bread is harmful. Feeding any kind of processed human food is harmful. Wildlife should not be fed when ample food is already available in nature. 1.) Feeding ducks attracts rats, pests and predators that kill ducks and endanger humans. 2.) Rotting food pollutes the water and breeds deadly diseases and parasites... • A single outbreak of Duck Virus Enteritis (caused by artificial feeding) kills all of the ducks. • Uneaten food quickly forms a deadly mold called Aspergillus; fatal to ducks without early diagnosis and expensive treatment. • Avian Botulism (caused by artificial feeding) kills entire waterfowl populations and hospitalizes people. • Artificially fed ducks emit a parasite causing a condition in humans called Swimmer's Itch. 3.) Ducks defacate at the site of scattered food or bread, bacteria in feces creates much higher risks for illness or disease. 4.) Most waterfowl die-offs in the past 10 years have been attributed to artificial feeding. 5.) Food waste bobbing on the water's edge is ugly. 6.) Ducks that are overfed create dangerous amounts of waste that harms fish and other animals living in ponds. 7.) Some foods like corn may be OK as a snack for ducks, but fish can't digest it and die. Seeds cause severe cramping pain in ducks. Related Posts
dclm_baseline
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// Copyright 2021 Google LLC // // Licensed under the Apache License, Version 2.0 (the "License"); // you may not use this file except in compliance with the License. // You may obtain a copy of the License at // // https://www.apache.org/licenses/LICENSE-2.0 // // Unless required by applicable law or agreed to in writing, software // distributed under the License is distributed on an "AS IS" BASIS, // WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. // See the License for the specific language governing permissions and // limitations under the License. package statequery import ( "fmt" "sync" "time" ) // Cache type to hold frequently requested responses from the Resource Manager API. type Cache struct { mutex sync.Mutex maxTTL time.Duration items map[string]*cacheItem } // Single cacheItem, timestamped to control freshness type cacheItem struct { updated time.Time projects []string } // Add an item to the cache func (cache *Cache) Add(key string, projects []string) { cache.mutex.Lock() cache.items[key] = &cacheItem{ updated: time.Now().UTC(), projects: projects, } cache.mutex.Unlock() } // Get an item from the cache. Will return items if available and fresh enough. func (cache *Cache) Get(key string) ([]string, error) { cache.mutex.Lock() item, ok := cache.items[key] if !ok { // Cache miss cache.mutex.Unlock() return nil, fmt.Errorf("key not in cache: %s", key) } // Cache hit // Check cache freshness diff := time.Now().UTC().Sub(item.updated) if diff >= cache.maxTTL { // Cache is stale delete(cache.items, key) cache.mutex.Unlock() return nil, fmt.Errorf("cache appears stale for key: %s", key) } // Cache item OK cache.mutex.Unlock() return cache.items[key].projects, nil } // Initialize and configure cache func (cache *Cache) Initialize(maxTTL time.Duration) { cache.items = make(map[string]*cacheItem) cache.maxTTL = maxTTL }
common_corpus
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On Wed, 27 Oct 2010 21:32:44 +0200, Patrick Dengler <patd@microsoft.com> wrote: ... > The following test cases include SMIL, which either is not integral to > the tests, or should be renamed/categorized as animate- > paths-dom-02-f.svg That test is not using smil, and is not complete/reviewed yet. What's your suggested new naming scheme for the tests that depend on declarative animation? Here's my proposal: pservers-grad-19-b.svg -> animate-pservers-grad-01-b.svg The criteria being that any test where declarative animation is a required part prefix the old name with 'animate-' and restart the numbering from 1. The test that are up for renaming are listed below. There are a few more in the filters section, a rough estimate of the total number of approved tests that are likely to be affected: 10-20. > struct-dom-08-f.svg Animation isn't integral to this test. Would trying to use window.setTimeout (if it exists) be ok? And if setTimeout is not found fallback to using an animate element. This is one of the tests for SVG 1.1F2 spec changes. > interact-events-203-t.svg > interact-pevents-07-t.svg For these tests I would like to see an equivalent test using script. > interact-pevents-02-t.svg No objections to renaming. There's an equivalent script-based test already: interact-pevents-01-b.svg. > interact-pevents-201-t.svg No objections to renaming. There's an equivalent script-based test already: interact-pevents-08-f.svg > interact-pevents-202-t.svg No objections to renaming. There's an equivalent script-based test already: interact-pevents-09-f.svg > script-elem-01-b.svg > struct-dom-09-b.svg > pservers-grad-19-b.svg No objections to renaming. Cheers /Erik -- Erik Dahlstrom, Core Technology Developer, Opera Software Co-Chair, W3C SVG Working Group Personal blog: http://my.opera.com/macdev_ed
mini_pile
{'original_id': 'e7941dfd51987b42018f31e4d9696e826bb8717eeba6323cbf8bb1eec88424f1'}
Ion exchange based volatile component removal device for ion chromatography ABSTRACT A method, device, and system for removing a volatile component from a liquid solution for a chromatographic separation are described. The method includes the flowing of a liquid solution through a first chamber of the device. A volatile component in the liquid solution is transported across a first ion exchange barrier from the first chamber to a second chamber. The first ion exchange barrier has a first charge. The second chamber includes an ion exchange packing having a second charge that is an opposite polarity to the first charge. The volatile component reacts with the ion exchange packing to create a charged component in the second chamber. The charged component having a third charge that is a same polarity to the first charge. The ion exchange packing is regenerated by electrolytically generating a hydronium or a hydroxide. CROSS-REFERENCE TO RELATED APPLICATION This application is a divisional under 35 U.S.C. § 121 and claims thepriority benefit of co-pending U.S. patent application Ser. No.14/540,786, filed Nov. 13, 2014. The disclosure of the foregoingapplication is incorporated herein by reference. BACKGROUND Ion chromatography (IC) is a widely used analytical technique for thechemical analysis and separation of charged molecules. IC involves theseparation of one or more analyte species from matrix components presentin a sample. The analytes are typically ionic so that they can have anionic interaction with a stationary phase. In IC, the stationary phaseincludes ionic moieties that ideally will bind to the charged analyteswith varying levels of affinity. An eluent is percolated through thestationary phase and competes with the analyte and any matrix componentsfor binding to the ionic moieties. The eluent is a term used to describea liquid solution or buffer solution that is pumped into achromatography column. During this competition, the analyte and anymatrix component will separate from each other by eluting off of thestationary phase as a function of time and then be subsequently detectedat a detector. Examples of some typical detectors are a conductivitydetector, a UV-VIS spectrophotometer, and a mass spectrometer. Over theyears, IC has developed into a powerful analytical tool that is usefulfor creating a healthier, cleaner, and safer environment where complexsample mixtures can be separated and analyzed for various industriessuch as water quality, environmental monitoring, food analysis,pharmaceutical, and biotechnology. Carbon dioxide is a gas present in air and can potentially contaminatethe sample or the eluent when performing IC. Carbon dioxide gas candissolve in liquid to form carbonic acid, bicarbonate, and carbonatespecies. In particular, the presence of carbonate from dissolved carbondioxide has been a source of interference for anion analysis with IC.The dissolution of carbon dioxide can raise the observed backgroundconductivity even after a suppression of the eluent. This not onlyaffects the peak response, but also makes peak integration difficult asthe background is not stable and constant. The presence of carbondioxide or carbonate in the sample can also be troublesome as the peakcorresponding to carbonate can overlap with other analyte peaks in thechromatogram. Gas permeable membranes can be used to remove dissolved carbon dioxidefrom the sample and/or the eluent. However, gas permeable membranes canbe fragile and have relatively poor pressure tolerance. Currently, thereis a trend to use increasing system pressure with smaller sizechromatographic media to obtain faster and higher resolution sampleseparations. In addition to being fragile, gas permeable membranes canbe expensive and difficult to manufacture with precise dimensions. Itshould be noted that the use of relatively thick walled membranes mayincrease the strength of the membrane, but will likely decrease theefficiency of gas removal and significantly increase expense. Gaspermeable devices typically require reagents such as base streams from areservoir or vacuum for driving the removal of the volatile component,which adds to the complexity of the device. As such, Applicant believesthat there is a need for volatile component removing devices that arerobust to high operating pressures, uses membranes made of relativelylow cost materials, and efficiently removes the volatile gases likecarbon dioxide without any external reagents or applying vacuum. SUMMARY A method of removing a volatile component from a liquid solution for achromatographic separation is described. The method includes flowing theliquid solution, that includes the volatile component, through a firstchamber. The volatile component can be transported across a first ionexchange barrier from the first chamber to a second chamber, where thefirst ion exchange barrier is at least partially disposed between thefirst chamber and the second chamber. The first ion exchange barrier canhave a first charge, allowing the flow of ions having a charge oppositeto the first charge, and does not allow bulk flow of the liquidsolution. The second chamber can include an ion exchange packing havinga second charge that is an opposite polarity to the first charge. Thevolatile component can react with the ion exchange packing to create acharged component in the second chamber. The charged component having athird charge that is a same polarity to the first charge. The ionexchange packing can be regenerated by electrolytically generating ahydronium or a hydroxide, in which the hydronium or the hydroxide is inelectrical communication with the ion exchange packing. In regards to the above method, the ion exchange packing can be inphysical contact with the first ion exchange barrier. In regards to any of the above methods, the electrolytically generatedhydronium is formed at an anode and the electrolytically generatedhydroxide is formed at a cathode. In regards to any of the above methods, the volatile component caninclude a weakly ionized species selected from the group consisting ofcarbon dioxide, carbonic acid, and combinations thereof. The liquidsolution can include an analyte, where the analyte includes an anion andthe first charge of the first ion exchange barrier is negative. In regards to any of the above methods, the ion exchange packing is in ahydroxide form where the carbonic acid reacts with the hydroxide form tocreate a negatively charged ion bound to the ion exchange packing. In regards to any of the above methods, the electrolytically generatedhydroxide is transported through the second chamber to regenerate theion exchange packing and to remove the negatively charged ion out of thesecond chamber. In regards to any of the above methods, the negatively charged ionincludes an ionic species selected from the group consisting ofcarbonate, bicarbonate, and combinations thereof. In regards to any of the above methods, the method further includesbefore the flowing of the liquid solution through the first chamber,suppressing the liquid solution with a suppressor that exchangespositively charged ions where the liquid solution contains an analyte.The analyte having a same charge as the first ion exchange barrier. In regards to the above method, the suppressing of the liquid solutionincludes adding hydronium to the liquid solution. In regards to any of the above methods, the method further includesflowing the liquid solution from the first chamber to a detector. Asignal can be measured that is proportional to an analyte concentration.The liquid solution can flow from the detector to the second chamber.The liquid solution can flow through the ion exchange packing and out ofthe second chamber to a cathode chamber, and then to an anode chamber. In regards to the above method, the cathode chamber includes thecathode, and a second ion exchange barrier is at least partiallydisposed between the cathode chamber and the second chamber. The secondion exchange barrier can have a positive charge, which allows the flowof negatively charged ions from the cathode chamber to the secondchamber, and does not allow bulk flow of the liquid solution. The methodfurther includes transporting the hydroxide through the second ionexchange barrier to the second chamber. In regards to the above method, the anode chamber includes the anode,and a third ion exchange barrier is at least partially disposed betweenthe anode chamber and the second chamber. The third ion exchange barriercan have a positive charge, which allows the flow of negatively chargedions from the second chamber to the anode chamber, and does not allowbulk flow of the liquid solution. The method further includestransporting the hydroxide from the second chamber to the anode chamber. In regards to any of the above methods, the volatile component mayinclude ammonia where the first charge of the first ion exchange barrieris positive. In regards to any of the above methods, the first ion exchange barrierincludes an ion exchange capillary tube or an approximately planarmembrane. In regards to any of the above methods, the liquid solution furtherincludes an analyte and an eluent. The method further includesconverting the analyte to a salt form in the first chamber. In regards to any of the above methods, the eluent includes a sodiumhydroxide. A first embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. The firstembodiment of the device can include a first chamber, a second chamber,and a first ion exchange barrier. The first chamber includes an inletconfigured to receive the liquid solution that includes the volatilecomponent, and an outlet configured to output the liquid solution with asubstantial portion of the volatile component removed. The secondchamber includes an ion exchange packing. The second chamber is inelectrical communication with a first cathode and a first anode. Thefirst cathode is configured to electrolytically generate a hydroxide,and the first anode is configured to electrolytically generate ahydronium. The first ion exchange barrier is at least partially disposedbetween the first chamber and the second chamber. The first ion exchangebarrier can have a first charge, allows the flow of the volatilecomponent and ions having a charge opposite to the first charge, anddoes not allow bulk flow of the liquid solution. The ion exchangepacking can have a second charge that is an opposite polarity to thefirst charge. The ion exchange packing is configured to react with thevolatile component to create a charged component having a same polarityas the first charge of the first ion exchange barrier, and the ionexchange packing is also configured to bind the charged component. In regards to any of the embodiments of the device, the ion exchangepacking is in physical contact with the first ion exchange barrier. In regards to any of the embodiments of the device, the volatilecomponent is selected from the group consisting of carbon dioxide,carbonic acid, and combinations thereof. The liquid solution includes ananalyte, where the analyte includes an anion and the first charge of thefirst ion exchange barrier is negative. In regards to any of the embodiments of the device, the ion exchangepacking is in the hydroxide form. In regards to any of the embodiments of the device, the negativelycharged ion includes an ionic species selected from the group consistingof carbonate, bicarbonate, and combinations thereof. In regards to any of the embodiments of the device, the ion exchangepacking includes a material selected from the group consisting of an ionexchange packing, an ion exchange screen, an ion exchange monolith, anda combination thereof. In regards to any of the embodiments of the device, the second and thirdion exchange barriers each include a membrane In regards to any of the embodiments of the device, the first ionexchange barrier includes an approximately planar membrane. A second embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. Thesecond embodiment can include features of any of the above embodimentsof the device where the second embodiment further includes a cathodechamber and an anode chamber. The cathode chamber includes the firstcathode, in which a second ion exchange barrier is at least partiallydisposed between the cathode chamber and the second chamber. The secondion exchange barrier can have a third charge that is an oppositepolarity to the first charge. The second ion exchange barrier isconfigured to not allow bulk flow of the liquid solution, and to allowthe flow of ions having a charge opposite to the third charge, from thecathode chamber to the second chamber. The anode chamber includes thefirst anode, in which a third ion exchange barrier is at least partiallydisposed between the anode chamber and the second chamber. The third ionexchange barrier can have a fourth charge that is an opposite polarityto the first charge. The third ion exchange barrier is configured to notallow bulk flow of the liquid solution, and to allow the flow of ionshaving a charge opposite to the fourth charge, from the second chamberto the anode chamber. In regards to the second embodiment of the device, the outlet of thefirst chamber can be fluidically connected to an inlet of a detector. Anoutlet of the detector can be fluidically connected to an inlet of thesecond chamber. An outlet of the second chamber can be fluidicallyconnected to an inlet of the cathode chamber. An outlet of the cathodechamber is fluidically connected to an inlet of the anode chamber. Anoutlet of the anode chamber can be fluidically connected to a wastechamber. In regards to the second embodiment of the device, the cathode chamberand the anode chamber can be disposed on opposing ends of the secondchamber. In regards to any of the above devices, the volatile component mayinclude ammonia where the first charge of the first ion exchange barrieris positive. In regards to any of the above devices, the first ion exchange barrierincludes an ion exchange capillary tube. A third embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. The thirdembodiment can include features of the above devices where the first ionexchange barrier includes a first approximately planar membrane. Thefirst anode and the first cathode are at least partially disposed in thesecond chamber. The first anode and the first cathode can each have aplanar surface, where a plane of the first planar membrane isapproximately perpendicular to planar surfaces of the first cathode andthe first anode. A fourth embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. Thefourth embodiment can include the features of the third embodiment wherethe fourth embodiment further includes a third chamber and a fourth ionexchange barrier. The third chamber includes the ion exchange packing. Asecond cathode and a second anode are at least partially disposed in thethird chamber. The second cathode is configured to electrolyticallygenerate a hydroxide, and the second anode is configured toelectrolytically generate a hydronium. The fourth ion exchange barrieris at least partially disposed between the first chamber and the thirdchamber. The fourth ion exchange barrier can have a same charge as thefirst ion exchange barrier, allows the flow of the volatile componentand ions having a charge opposite to the first charge, and does notallow bulk flow of the liquid solution. The ion exchange packing canhave the second charge, in which the fourth ion exchange barrierincludes a second approximately planar membrane. The second anode andthe second cathode can each have a planar surface, where a plane of thesecond approximately planar membrane is approximately perpendicular toplanar surfaces of the second cathode and the second anode. A fifth embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. The fifthembodiment can include features of the above first or second embodimentof a device where the first ion exchange barrier includes a firstapproximately planar membrane. The first anode and the first cathode areat least partially disposed in the second chamber. The first anode andthe first cathode can each have a planar surface, where a plane of thefirst planar membrane is approximately parallel to planar surfaces ofthe first cathode and the first anode. A sixth embodiment of a device to remove volatile components from aliquid solution for a chromatographic separation is described. The sixthembodiment can include the features of the fifth embodiment where thesixth embodiment includes a third chamber including the ion exchangepacking. A second cathode and a second anode are at least partiallydisposed in the third chamber. The second cathode is configured toelectrolytically generate a hydroxide, and the second anode isconfigured to electrolytically generate a hydronium. A fourth ionexchange barrier is at least partially disposed between the firstchamber and the third chamber. The fourth ion exchange barrier can havea same charge as the first ion exchange barrier, allows the flow of thevolatile component and ions having a charge opposite to the firstcharge, and does not allow bulk flow of the liquid solution. The ionexchange packing can have the second charge, in which the fourth ionexchange barrier includes a second approximately planar membrane. Thesecond anode and the second cathode can each have a planar surface,where a plane of the second approximately planar membrane isapproximately parallel to planar surfaces of the second cathode and thesecond anode. A system to analyze a sample containing a volatile component isdescribed. The system includes a volatile component removing device asdescribed above and at least one chromatography component selected fromthe group consisting of a suppressor configured to remove eluentcounterions where the eluent counterions have a charge opposite to ananalyte ion where the suppressor is disposed upstream of the volatilecomponent removing device, a pump disposed upstream of the volatilecomponent removing device, a chromatography column fluidically connectedto the volatile component removing device, a detector disposeddownstream of the volatile component removing device, and combinationsthereof. BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which are incorporated herein and constitutepart of this specification, illustrate presently preferred embodimentsof the invention, and, together with the general description given aboveand the detailed description given below, serve to explain features ofthe invention (wherein like numerals represent like elements). FIG. 1 illustrates a schematic embodiment of a volatile componentremoval device for chromatography. FIG. 2 is a simplified schematic embodiment of the volatile componentremoval device in accordance with FIG. 1, which schematicallyillustrates the gas and ion flows. FIG. 3 illustrates another schematic embodiment of a volatile componentremoval device that does not have a separate anode chamber and a cathodechamber. FIG. 4 is a chromatogram of a sample containing fluoride (1), chloride(2), and carbonate (3) and did not use a volatile component removaldevice. FIG. 5 is a chromatogram of a sample containing fluoride (1), chloride(2), and carbonate (3) where a volatile component removal device wasused in accordance with FIG. 1. FIG. 6 is a chromatogram of a seven anion test mixture containingfluoride (1), chloride (2), carbonate (3), nitrite (4), sulfate (5),bromide (6), nitrate (7), and phosphate (8) that did not use a volatilecomponent removal device. FIG. 7 is a chromatogram of the seven anion test mixture containingfluoride (1), chloride (2), nitrite (4), sulfate (5), bromide (6),nitrate (7), and phosphate (8) where a volatile component removal devicewas used in accordance with FIG. 1. FIG. 8 illustrates an exemplary chromatography system suitable for usewith the volatile component removal devices described herein. FIG. 9 illustrates a schematic embodiment of a combination deviceconfigured to suppress an eluent stream and remove volatile componentsfor chromatographic analysis. FIG. 10 illustrates another schematic embodiment of a volatile componentremoval device which is based on a flat membrane configuration whereelectrolytically generated hydroxides flow in a direction influenced byan electric field parallel to the liquid stream containing the volatilecomponent. FIG. 11 illustrates another schematic embodiment of a volatile componentremoval device which is based on a flat membrane configuration whereelectrolytically generated hydroxides flow in a direction influenced byan electric field perpendicular to the liquid stream containing thevolatile component. FIG. 12 illustrates another schematic embodiment of a volatile componentremoval device which is similar to the device of FIG. 10 except that ithas only one side channel. FIG. 13 illustrates another schematic embodiment of a volatile componentremoval device which is similar to the device of FIG. 11 except that ithas only one side channel. DETAILED DESCRIPTION OF EMBODIMENTS The following detailed description should be read with reference to thedrawings, in which like elements in different drawings are identicallynumbered. The drawings, which are not necessarily to scale, depictselected embodiments and are not intended to limit the scope of theinvention. The detailed description illustrates by way of example, notby way of limitation, the principles of the invention. This descriptionwill clearly enable one skilled in the art to make and use theinvention, and describes several embodiments, adaptations, variations,alternatives and uses of the invention, including what is presentlybelieved to be the best mode of carrying out the invention. As usedherein, the terms “about” or “approximately” for any numerical values orranges indicate a suitable dimensional tolerance that allows the part orcollection of components to function for its intended purpose asdescribed herein. Carbonate contamination can stem from the sample or from the eluent. Thepresence of carbonate from the sample can result in a fairly broadchromatographic peak that could potentially co-elute with analytes ofinterest making quantitation difficult. The presence of carbonate in theeluent, particularly under gradient conditions, can be an issue wherecarbonate appears as a chromatographic peak that interferes with otherpeaks of interest. When using manually prepared eluents such ashydroxide, the exposure to air causes carbon dioxide to manifest itselfas carbonate in the eluent. The presence of carbonate causes an elevatedcarbonic acid background when performing anion analysis with suppressedconductivity detection. With isocratic elution, the higher backgroundfrom this type of contamination can impact the peak response since thebackground after suppression for anion analysis would be carbonic acid.The carbonic acid background would depress the peak signal from acidsthus resulting in lower response for all analytes. With gradient elution in addition to the higher background there is alsoa possibility that the peak corresponding to the residual carbonate inthe eluent can interfere with the quantitation of specific ions such assulfate. During anion analysis, the residual carbonate in the eluent canget focused during the gradient on the analytical column and elutes as acarbonate peak. Since carbonate after suppression is a weak acid, itelutes as a broad peak and can interfere with species such as sulfatewhich elutes in the near vicinity of carbonate in many columns. Anotheraspect of the carbonate eluent contamination is the higher backgroundthat, during a gradient, increases with increasing ionic strength. Thenet effect is changing baselines that make integration difficult. The following will describe a general chromatography system suitable foruse with volatile component removal devices described herein. FIG. 8illustrates an embodiment of chromatography system 800 that includes apump 802, an electrolytic eluent generating device 804, a degas assembly810, an injection valve 812, a chromatographic separation device 814, asuppressor 813, volatile component removal device 815, a detector 816,and a microprocessor 818. A recycle line 820 may be used to transfer theliquid from an output of detector 816 to a regenerant portion ofvolatile component removal device 815. Pump 802 can be configured to pump a liquid from a liquid source and befluidically connected to electrolytic eluent generating device 804. Inan embodiment, the liquid source may be deionized water, or an aqueoussolution with electrolyte(s). Under certain circumstances where theliquid source for the pump 802 has an aqueous solution withelectrolytes, the chromatography system 800 may be operated without theuse of eluent generating device 804 and degas assembly 810. Pump 802 canbe configured to transport the liquid at a pressure ranging from about20 pounds per square inch (PSI) to about 6000 PSI. Under certaincircumstances, pressures greater than 6000 PSI may also be implemented.It should be noted that the pressures denoted herein are listed relativeto an ambient pressure (13.7 PSI to 15.2 PSI). Pump 802 may be in theform of a high pressure liquid chromatography (HPLC) pump. In addition,pump 802 can also be configured so that the liquid only touches an inertportion of pump 802 so that a significant amount of impurities does notleach out. In this context, significant means an amount of impuritiesthat would interfere with the intended measurement. For example, theinert portion can be made of polyetherether ketone (PEEK) or at leastcoated with a PEEK lining, which does not leach out a significant amountof ions when exposed to a liquid. Electrolytic eluent generating device 804 is configured to generate aneluent such as for example KOH or methanesulfonic acid. An eluent is aliquid that contains an acid, base, salt, or mixture thereof and can beused to elute an analyte through a chromatography column. Detailsregarding electrolytic eluent generating devices can be found in U.S.Pat. Nos. 6,225,129 and 6,682,701, which are hereby incorporated byreference herein. Degas assembly 810 can be used to remove any electrolytic gases in theeluent stream. In an embodiment, a residual gas may be carbon dioxide,hydrogen, and oxygen. The gas can be swept out of degas assembly 810using a wash fluid that flows through a low pressure channel of degasassembly 810, as described in U.S. Pat. No. 8,414,684, which is herebyincorporated by reference herein. Degas assembly 810 may include atubing section that is gas permeable and liquid impermeable such as, forexample, amorphous fluoropolymers or stretched polytetrafluoroethylene(commercially available under the trade names Teflon AF and Gore-Tex).The flowing liquid can be outputted from degas assembly 810 to injectionvalve 812 with a substantial portion of the gas removed. While FIG. 8shows that the eluent generator and the degasser modules are at the highpressure side of the pump, it is possible to install the eluentgenerator and the degasser modules at the low pressure side of the pump(not shown). In this embodiment, the generated eluent is pumped throughthe pump and then to the chromatographic separation device. Under certain circumstances where the electrolytic gases in the eluentstream have oxygen and hydrogen gas, an optional catalytic gaselimination column may be used to convert oxygen and hydrogen to water.Details regarding catalytic gas elimination devices can be found in U.S.Pat. Nos. 7,329,346 and 8,043,507, which are hereby incorporated byreference herein. Injection valve 812 can be used to inject a bolus of a liquid sampleinto an eluent stream. The liquid sample may include a plurality ofchemical constituents (i.e., matrix components) and one or more analytesof interest. Sample injection valve 812 will typically have at least twopositions. In the first position, eluent will simply flow throughinjection valve 812 to chromatographic separation device 814 and aliquid sample can be loaded into a sample loop having a predeterminedvolume in injection valve 812. Once injection valve 812 is switched tothe second position, eluent will flow through the sample loop and thenintroduce the liquid sample to chromatographic separation device 814. Inan embodiment, injection valve 812 can be in the form of a six portvalve. Chromatographic separation device 814 can be used to separate variousmatrix components present in the liquid sample from the analytes ofinterest. This separation provides information on the chemicalcomponents present in the sample and concentration levels. Typically,chromatographic separation device 814 may be in the form of a hollowcylinder that contains a stationary phase. As the liquid sample flowsthrough chromatographic separation device 814, the matrix components andtarget analytes can have a range of retention times as they are elutingoff of chromatographic separation device 814. Depending on thecharacteristics of the target analytes and matrix components, they canhave different affinities to the stationary phase in chromatographicseparation device 814. An output of chromatographic separation device814 can be fluidically connected to detector 816 to measure the presenceand amount of the separated chemical constituents of the liquid sample.As illustrated in FIG. 8, suppressor 813 and volatile component removaldevice 815 are in between chromatographic separation device 814 anddetector 816. Suppressor 813 can be used to suppress the conductivity of the eluentand increase the conductivity of the fully dissociated analyte. In anembodiment, the eluent may be sodium hydroxide that is neutralized towater and the analyte may be chloride anion that is converted to a moreconductive hydrochloric acid. Embodiments of suppressors are describedin U.S. Pat. Nos. 4,999,098; 5,248,426; and 5,352,360, which are herebyincorporated by reference herein. An output of chromatographicseparation device 814 can be fluidically connected to suppressor 813. Volatile component removal device 815 is configured to remove volatilecomponents from the effluent stream such as carbon dioxide or ammonia.In particular, volatile component removal device 815 can be especiallywell suited for removing carbon dioxide and carbonic acid, which isimportant for reducing background conductivity of the effluent stream,before the effluent flows to the detector 816. Carbon dioxide isreferred to as a volatile component because it is a gas. Carbonic acidis also referred to as a volatile component because it is in equilibriumwith carbon dioxide gas and water, as illustrated by Equation 1. Inaddition, carbonic acid can dissociate into hydrogen ion, bicarbonateion (HCO₃), and carbonate ion (CO₃ ²⁻). CO₂+H₂O←→H₂CO₃←→H⁺+HCO₃ ⁻+CO₃ ²⁻  (Eq. 1) Detector 816 may be in the form of an electrochemical detector, aconductometric detector, an optical detector, a charge detector, or acombination thereof. Details regarding the charge detector that is basedon a charged barrier and two electrodes can be found in U.S. Pat. No.8,293,099, which is hereby fully incorporated by reference herein. An electronic circuit may include microprocessor 818 and a memoryportion. Microprocessor 818 can be used to control the operation ofchromatography system 800. Microprocessor 818 may either be integratedinto chromatography system 800 or be part of a personal computer thatcommunicates with chromatography system 800. Microprocessor 818 may beconfigured to communicate with and control one or more components ofchromatography system such as pump 802, electrolytic eluent generatingdevice 804, injection valve 812, suppressor 813, volatile componentremoval device 815, and detector 816. Note that chromatography system800 is a particular machine used to analyze standard solutions andsample solutions to identify chemical constituents and the associatedconcentration values. Now that a general chromatography system has been described thatincludes a volatile component removal device, the following willdescribe the volatile component removal devices in more detail. FIG. 1illustrates a schematic embodiment of a volatile component removaldevice 815 for chromatography. Volatile component removal device 815 mayinclude a first chamber 102, a second chamber 104, an anode chamber 106,a cathode chamber 108, a first ion exchange barrier 110, a second ionexchange barrier 112, a third ion exchange barrier 114, and an ionexchange packing 116. It should be noted that a chamber that includes aninlet and an outlet may also be referred to as a channel. Referring to FIG. 1, first chamber 102 includes an inlet 118 configuredto receive the liquid solution that includes the volatile component, andan outlet 120 configured to output the liquid solution with asubstantial portion of the volatile component removed. The liquidsolution entering inlet 118 may be an output of a suppressor, aninjection valve, or an eluent generator. The volatile component may be achemical dissolved in the liquid solution and/or a gas associated withthe liquid solution such as for example, carbon dioxide, carbonic acid,and ammonia. The substantial portion of the volatile component removedmay be greater than about 50%, preferably greater than about 75%, morepreferably greater than about 90%, and yet more preferably greater thanabout 95%. Referring back to FIG. 1, second chamber 104 includes an ion exchangepacking 116. Ion exchange packing 116 may in the form of a resin, ascreen, a monolith, or a combination thereof. Second chamber 104 is inelectrical communication with a cathode 122 and an anode 124. Electricalcommunication includes a flow of electrons and/or ions between cathode122 to anode 124 via second chamber 104. Cathode 122 is configured toelectrolytically generate hydroxide. Anode 124 is configured toelectrolytically generate a hydronium. Note that the terms hydronium(H₃O⁺) and hydrogen ion (H⁺) are used interchangeably. Cathode 122electrolytically splits water into hydroxide and hydrogen gas during anelectrochemical reduction. Anode 124 electrolytically splits water intohydronium and oxygen gas during an electrochemical oxidation. Asillustrated in FIG. 1, for anion analysis the hydroxide generation isproximate to outlet 125 of second chamber 104. This configurationensures that the outlet portion of the anion exchange packing 116 inchamber 104 is fully regenerated and is not exposed to any residualcarbonate. Also this configuration ensures that any carbonic acidgenerated at the anode is not exposed to the aqueous stream flowing outof the volatile component removal device. Referring to FIG. 1, cathode122 is denoted as the negatively charged electrode and anode 124 isdenoted as the positively charged electrode. A constant current orvoltage source can be used to drive the electrolytic reactions atcathode 122 and anode 124. In an alternative embodiment, the voltage or current polarity may bereversed where the location of the cathode and anode, as illustrated inFIG. 1, is switched on the volatile component removal device 815. Inthis configuration there is potential for transport of the removedvolatile component back into the aqueous stream as discussed above andtherefore is not the preferred configuration. First ion exchange barrier 110 is at least partially disposed betweenthe first chamber 102 and the second chamber 104. As illustrated in FIG.1, an inlet portion and an outlet portion of first ion exchange barrier110 is outside of second chamber 104 and a middle portion of first ionexchange barrier 110 is inside of second chamber 104 and in physicalcontact with ion exchange packing 116. Where first ion exchange barrier110 is a cation exchange membrane, it may be of a material such assulfonated tetrafluoroethylene (e.g. Nafion) or otherfluoropolymer-copolymer. First ion exchange barrier 110 may be in theform of an ion exchange capillary tube. An inner portion of the ionexchange capillary tube can form first chamber 102. In an embodiment,the ion exchange capillary tube can be in a coiled arrangement so thatit can be sufficiently long and fitted within second housing. The ionexchange capillary tube may have an inner diameter (id.) ranging fromabout 0.001 inches to 0.1 inches and an outer diameter (od.) rangingfrom 0.005 inches to 0.2 inches. The diameter is chosen in proportion tothe chromatographic format of operation. For example for the capillaryformat of operation the membrane dimensions were 0.004 inches id. and0.01 inches od. The membrane dimensions are chosen to ensure goodvolatile component removal and acceptable band dispersion particularlywhen the volatile component removal device is installed between thesuppressor and the detector cell. For sample pretreatment applicationsband dispersion may not be a consideration therefore the dimensions arechosen purely from a volatile component removal perspective.Alternatively, first ion exchange barrier may include a substantiallyflat sheet. First ion exchange barrier 110 should have a positive or negative chargeso as to reduce the likelihood of back diffusion of the volatilecomponent back into first chamber 102. For example, in the case ofremoving carbon dioxide or carbonic acid, the neutral fraction would befreely transported across a cation exchange membrane which has anegative charge stemming from the stationary sulfonated functionalities.The reaction of the removed carbonic acid with the anion exchangematerial on the other side of the membrane results in formation ofcarbonate anion as a counterion to the anion exchange material. In thiscase the carbonate anion would be repelled by the negative charge on thecation exchange membrane thus minimizing diffusion of the removedvolatile component anion back into the aqueous stream. First ion exchange barrier 110 has a first charge and by design allowsthe flow of ions having a charge opposite to the first charge, and doesnot allow bulk flow of the liquid solution. Because the volatilecomponents of interest are a weakly ionized species, a predominantproportion of the weakly ionized species is neutral and can be easily betransported across the first ion exchange barrier 110. A weakly ionizedspecies refers to the situation where only a small proportion of thevolatile component is ionized (HCO₃ ⁻ or CO₃ ²⁻) and the predominantproportion has a neutral charge (H₂CO₃). In an embodiment, a predominantproportion can refer to a situation that is 90% or greater H₂CO₃. Ionexchange packing 116 has a second charge that is an opposite polarity tothe first charge. In an embodiment, first ion exchange barrier 110 canhave a first charge that is negative and exchanges positively chargedions. Note that when the first charge is negative, then a negativelycharged analyte will not traverse first ion exchange barrier 110.Neutral molecules and gaseous molecules can be transported through thefirst ion exchange barrier 110. For example during anion analysis thefirst ion exchange barrier 110 could be a cation exchange membrane thatis negatively charged owing to the sulfonated charges on the membrane. Asuitable membrane would be a sulfonated membrane prepared by a radiationgrafting process as described in Examples 1 and 2 in U.S. Pat. No.4,999,098 and in Example 1 in U.S. Pat. No. 6,077,434, which is herebyfully incorporated by reference herein. This membrane would allowtransport of cationic moieties which are the counterions to thestationary charges on the membrane. Negatively charged moieties would berepelled by the stationary negative charges on the cation exchangemembrane. Neutral molecules can be transported across the membrane. Ionexchange packing 116 is an anion exchanger with stationary positivelycharged substrate material. This material is capable of exchanging andretaining anions. Suitable materials include primary, secondary,tertiary, or quaternary amine functionalized inorganic or organicparticles. The most preferred anion exchange packing materials includesquaternary amine functionalized inorganic or organic particles. The substrate materials for the first ion exchange barrier can be chosenso that the device back pressure resiliency is high. For example withpolyethylene, polypropylene, or polytetrafluoroethylene substrates, thedevice can easily operate with backpressures exceeding 200 PSI or moreso long as the substrate is sufficiently thick. The polyethylene orpolypropylene may be in the form of a woven monofilament. Thepolyethylene, polypropylene, or polytetrafluoroethylene substrates canthen be derivatized with ion exchange functionality using radiationgrafting. With substantially flat membranes (i.e. planar membranes),volatile component removal devices can operate reliably up to 800 PSI.This higher pressure resilience allows devices with substantially flatmembranes to be used with multiple detectors. Other volatile componentremoval devices have used CELGARD® membranes (polyethylene and/orpolypropylene) that are microporous and relatively thin. Such devicesusing CELGARD® membranes do not operate reliably at greater than 100PSI. Neutral volatile component such as carbon dioxide or carbonic acid canbe transported across the cation exchange membrane where the volatilecomponent then reacts with the hydroxide ions present on the anionexchange packing and becomes converted to carbonate or bicarbonateanion, which are retained on the anion exchanger. The electrolysisgenerated hydroxide ions generated at the cathode are transported acrosssecond chamber 104 to regenerate the anion exchange packing 116. Theanions on anion exchange packing are driven to the anode by the appliedvoltage and combine with the electrolytically generated hydronium ionsto form water or carbonic acid which is removed out of the device. Thus,volatile component removal is feasible in the present device. Since theanion exchange packing is continuously regenerated there is no need foradditional reagents or additional external pumps. The water required forthe electrolysis can be derived by recycling the aqueous stream from thedetector, and thus, the device can operate without any addedregenerative reagents. It should be noted that, for anion analysis, themembrane has to have an anionic stationary charge with exchangeablecations. The device will not operate properly for anion analysis wherethe first ion exchange barrier has a charge opposite the anion analyte.For example, a first ion exchange barrier having a cationic stationarycharge with exchangeable anions will retain the anion analytes ofinterest. For cation analysis, the opposite configuration would work well forcation analysis where the first ion exchange barrier has a cationicstationary charge with exchangeable anions. In this case, the volatilecomponent can be ammonia in equilibrium with ammonium ion (NH₄ ⁺) wherethe ammonium ion will be retained by an ion exchange packing that is acation exchanger. Regeneration of the cation exchange packing ensuresthat the device would operate continuously. Thus, the devices describedherein can provide a) a removal of the volatile component from a liquidstream, b) a retention of the removed volatile component on anoppositely charged ion exchange packing, c) a continuous operation toregenerate the oppositely charged ion exchange packing, and d) a recyclemode with electrolytic generation of hydroxide and hydronium negatingthe need for added regenerative reagents. Ion exchange packing 116 is configured to react with the volatilecomponent to create a charged component having a same polarity as thefirst charge of the first ion exchange barrier 110. This configurationensures that the removed species in the ionic form is repelled from theion exchange barrier 110 and therefore removed permanently. The ionexchange packing 116 is also configured to bind the charged component.In an embodiment, the ion exchange packing 116 includes an ion exchangeresin and is in physical contact with the first ion exchange barrier110. For example, as illustrated in FIG. 2, either carbon dioxide or carbonicacid can diffuse through first ion exchange barrier 110. Note thatcarbon dioxide can be hydrated with water to form carbonic acid withineither first chamber 102 or second chamber 104. Where the ion exchangepacking 116 is an anion exchange packing in a hydroxide form, carbonicacid can react with the hydroxide ion on the anion exchange packing toform charged components such as carbonate or bicarbonate. The resultingcarbonate or bicarbonate can then be bound by ion exchange packing 116.Note that the charged components carbonate and bicarbonate have anegative charge which is the same polarity as first ion exchange barrier110. Thus, the conversion of the volatile component to the charged formand binding of the negatively charged components to ion exchange packing116 and the repulsive Donnan forces of the first ion exchange barrier110 reduces the likelihood of the volatile component diffusing back intothe first chamber 102. Applicant believes that the added Donnan forcescombined with an intimate interaction between the ion exchange packingand the first ion exchange barrier provided the surprising result of anincreased efficiency in removing volatile component removal whencompared to degas assemblies using neutral membranes such as silicone.An example of a silicone based carbon dioxide removal device isdescribed in U.S. Pat. No. 7,306,720, which is hereby fully incorporatedby reference herein. Applicant also believes that the hydroxide form ofion exchange packing 116 traps carbonate and bicarbonate moreefficiently than hydroxide in solution. Further the facile electrolyticregeneration of the ion exchange packing 116 also allows for continuousoperation without disturbing the removal function. In one embodiment, the volatile component includes carbon dioxide,carbonic acid, or a combination thereof, the liquid solution includes ananion as the analyte, and the first charge of the first ion exchangebarrier 110 is negative. In this embodiment, the anion analyte does notbind to the negatively charged first ion exchange barrier 110. In another embodiment, the volatile component includes ammonia, theliquid solution includes a cation as the analyte, and the first chargeof the first ion exchange barrier is positive. In this embodiment, thecation analyte does not bind to the positively charged first ionexchange barrier. Referring back to FIG. 1, cathode chamber 108 includes cathode 122, andanode chamber 106 includes an anode 124. In an embodiment, cathodechamber 108 and anode chamber 106 are disposed on opposing ends ofsecond chamber 104. A second ion exchange barrier 112 is at leastpartially disposed between the cathode chamber 108 and the secondchamber 104. Second ion exchange barrier 112 has a third charge that isan opposite polarity to the first charge. Second ion exchange barrier112 is configured to not allow bulk flow of the liquid solution, and toallow the flow of ions having a charge opposite to the third charge,from the cathode chamber 108 to the second chamber 104. For example, thethird charge can be positive that corresponds to an anion exchangebarrier (e.g., second ion exchange barrier 112) where the first chargeis negative that corresponds to a cation exchange barrier (e.g., firstion exchange barrier 110).
common_corpus
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<?php use BitGrail\Ticker; class TickerTest extends PHPUnit\Framework\TestCase { private $ticker; public function setUp() { $this->ticker = new Ticker(); } public function testTickerSuccessCall() { $response = $this->ticker->call(); $this->assertObjectHasAttribute('last', $response); } } ?>
common_corpus
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Site Feedback Resolved questions For learning: English Base language: Chinese (Mandarin) Category: WK087 Please enter between 2 and 2000 characters. Sort by: Best Answer - Chosen by Voting Let me have a try. The ancient character "羊" has featured the frontal of the sheep head. The sheep was one of the important domestic animals in the ancient animal husbandry. The ancestors offered the sheep as sacrifice to the gods to pray for the peace and happiness. The sheep was placed beside "示" which meant the tablet belonging to the gods. "示", as a componet showing the meaning, suggests auspicious and lucky. "祥" consists of the two components of "示" and "羊" which suggests the pronounceation of the character, this kind of phonomenon is called echoism in Chinese. Therefore, "祥" is a associative and pictophmetic character. Submit your answer Please enter between 2 and 2000 characters.
dclm_baseline
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Thursday, September 8, 2016 Fleetwood Mac - Tango In the Night - 1987  So, I blame this one on my parents.  I'm busy listening to Duran2, Cure, New Order, Punk, Hard Rock, 80s Synth, Post Punk, EVERYTHING, but late Classic Rock/Adult Contemporary.  In my wildest dreams, I would've never listened to an album like this, let alone own one.  But, as a teen still living with my folks, a lot of the time I was forced to listen to their music (sorta like I do to my kids now) and they both thought this was a pretty good album when it came out.  For the longest time, I thought it was a 70s album, being ignorant of Fleetwood Mac in general.  Why would I bother to know the facts? So, several years back, I got nostalgic for this album.  Remembering my parents listening to it, and I recalled a lot of the tunes.  To learn it actually was an 80s album was somewhat shocking to me.  I thought most of them were dead by then or something (even now, none of them are dead.  Stupid, stupid man)  To also learn, while searching for the b-side material, that there were remixes of their songs was even more surprising. The b-side songs and remixes are rather meh.  But, if you are a completist, it doesn't matter.  I'm pretty sure I have it all here.  There might be a remix or two that didn't make the cut, I can't remember.  But, there's more than enough here to make you feel like you've had enough by the time the disc is done. It IS solid material, just not always my style.  As I said, it's a nostalgia thing.  But, to each his own, some of you may absolutely love this one.... 1. On here especially, Christine is the shit. The public always thinks of Lindsey and Stevie first. But the best singles were always Christine's.
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California Indians / Identifications of Tribes / Life What is the main function of the mission and what specific trees were found on most missions? The main purpose of all of the missions from the viewpoint of the Spanish Crown was to confirm the claim of Spain to this wilderness by settling it and creating communities (and ultimately four presidios or forts) that would defend the land. The purpose of the missions from the perspective of the padres was to convert the Native Americans, who were recruited into the missions and converted to Catholicism. Why is the Mission San Diego de Alcala called the "Mother of all Missions? The origins of the “official” name for first California mission (San Diego de Alcala) and the reference to this as the “Mother of all Missions” is a little convoluted. San Diego Bay was discovered by Juan Rodriquez Cabrillo in 1542 but given its present name by Captain Sebastian Vizcaino when he explored the coast in 1602. The name was subsequently applied to both the first Spanish presidio (fort) and the first mission in Alta California by Fr. Junipero Serra at the official founding of the mission, on July 16, 1769. Did the Indians play any games that were like foodball or baseball? The Indians played many "Field" games. The "balls" were made of natural material, stuffed animal skins, natural wooden knots, polished stones, hemp etc. Shinny games in which the ball or puck is moved with a stick were quite common.There were many variations but these were team games (with three to ten players, typically) with rules and an object (to get the ball past the other team, through posts or into a hole. Were Indians allowed to take communion? This is really a subject for an expert on the details of Catholic religious practices in Spain and Spanish America. As I recall (and I studied this a long time ago) the Council of Trent, which convened three times between 1545-1563 standardized the Mass and many other religious practices throughout the world. I believe they also ruled that it was not necessary to receive both "bread and wine" and that the Body of Christ was fully present in the "bread" which was much easier and safer to use. I have no information on the exact form and nature of the communion wafers. What was life like for the Indian children living at the mission? As you probably have already learned, the missions varied in size. San Carlos Borromeo de Carmelo was one of the most prominent missions but the neophyte population was smaller than the average. There were only 876 neophytes at Mission Carmel in 1795, twenty five years after the mission was founded, and this was the peak year. By 1832, the population had declined to 185 (this was the year the mission was secularized). Unfortunately the Europeans introduced many diseases (like small pox) to which the Indians had no immunity. What work did the Indians perform at Santa Ines? The work didn't vary a lot from mission to mission, although Santa Ines had one of the largest networks of ranches and agricultural fields in the mission chain, where they grew wheat, barley, corn, beans etc. Even today the Santa Inez valley is rich farming country. What was daily life like at Mission Soledad for both the Padres and the Native Americans? Please look at what is posted on our website ( ) under Ask The Expert. The are explanations of why they rang the bells, the work performed by the neophytes, what daily life was like and other facts you can use. The short answer is that daily life was very regimented. It started with religious services. Everyone was very busy all day long working. They ate three times a day. What effect did the small pox have on the indians of the mission if any? Periodic smallpox outbreaks and other European diseases affected the Indians particularly hard as they had no immunity. Experts estimate that European diseases accounted for about one third of the deaths of Native Americans in California after the Europeans arrived. Sadly, this phenomenon was not unique to California and even more severe among other Native American populations. In 1617–1619, for example, smallpox wiped out 90% of the Massachusetts Bay Native Americans.It reached Mohawks in 1634, Lake Ontario in 1636, and the lands of the Iroquois by 1679.
dclm_baseline
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Robotech: Invasion The year is 1999. During the height of a global war between the people of Earth, a large alien spacecraft enters and crashes in the South Pacific. A cease-fire is called between all humans, and a global unity is created while work begins on weapons to eradicate the alien threat. Nearly forty years have passed. It is now 2038. Major Earth population centres are destroyed, others simply abandoned. The few remaining resistance groups are attempting to fight the alien life known as the Invid releasing the Earth from the extra-terrestrial clutches. Ad FeedbackAdvertisement The third Robotech war has begun. Developed by Vicious Cycle, Robotech: Invasion is based on the anime series shown in over 140 countries in the early 90’s. The game holds true to the anime series, taking place in the third, and last section of the Robotech timeline, known as the ‘New Generation’. You take the role of a soldier named Locke who has regular flashbacks to his blurry past of being held captive by the Invid for the past four years. Your main intention is to obliterate the Invid race, bringing Earth back to human authority. The Invid are harvesting matter called ‘protoculture’; which is used for powering Invid and human’s weaponry and vehicles. Aside from the story centering around Locke (who is the main character which you control), from time to time you will also control Tasha, a Robotech scout. From the second level onwards, you are able to navigate the terrains in either soldier mode (on-foot) or on motorbike, made possible by your high-tech, transformable cyclone armour. On foot the gameplay is fairly good, and it’s easy to target and shoot enemy Invid with the on-screen target. For bigger enemies such as the flying Invid, you are able to ‘lock-on’ to that enemy by targeting it normally and holding the L1 button. This now allows you to move the target, which has become a small dot to aim at more precise parts of the alien’s body for better damage without fear of losing track of the enemy altogether. While on foot you are able to swap views between first-person and third-person, and as you advance in the game, you’ll be able to acquire such features as night-vision and heat sensitivity. However, motorcycle mode is where it turns ugly. The motorcycle is at best a chore to attempt to drive, as it feels clunky and awkward. Driving the motorbike seems slow and unnatural, and you will often find yourself pressing the boost button to speed it up only to drive yourself into an invisible barrier near the edges of the map, or flying over a bump and smashing into a wall. Once these things happen, you’ll be reverted back into soldier form, all ready to transform back into the bike for another go at it. While the motorcycle is good to get you from point A to point B, you can not use it inside buildings, or tunnels no matter how safe you believe you can drive it. In battles the motorbike performs even worse, as you no longer have your armour to protect you from enemy attack, and there is also the fact that you can only lock onto enemies and shoot the targets with inaccurate and weak missiles while on the bike. You’ll find yourself only using the bike as transportation, leaving all the combat to the much better soldier mode. Another gripe with gameplay is the ability to climb ladders, or lack-thereof. While you can indeed climb ladders, I’ve found it sometimes near impossible to actually get up the thing. The concept seems simple, walk towards the ladder and you’ll start climbing, then hold the ‘up’ button to go up to the top. While the latter part of that works fine, you may find yourself often wondering how, or why you can’t seem to climb a certain ladder. It seems that you quite often have to approach the ladder from a very specific direction and need to be a defined distance away from the ladder to actually be able to get up it. While it is a small gripe, it’s one which may bug you, as it did to me. Combat itself isn’t without its hitches though, despite the fact that the fighting is fairly well done, and is on par with other games of the same genre, Robotech: Invasion has a tendency in some places to throw many enemies at you, over and over again, so you may find yourself fighting the same re-spawning enemies for minutes after minutes. Although, with that said, the fighting system is good with the ability to use your weapon as a melee attack by pressing L2 button, throw grenades with the R2 button and zoom in by pressing in R3. The game does sport an online mode, which when working does produce a fairly good game, compared with the actual Robotech storyline gameplay. However the issue is that it is near impossible to go online and either find a server to play on, or anybody to play against. Sure you can create a match and walk around the map all by yourself, picking up weapons and waiting for someone to enter, but it doesn’t feel the same as a chaotic fragfest that it should be. Robotech: Invasion doesn’t bring anything new in the graphics department, although that’s not to say that the graphics are bad. They are what you’d normally come to expect from first-person shooters, albeit a bit more mild. The most colour you’ll see in the game are from the enemies who are quite often sporting shades of red or blue, while the ground stays a consistent brown for dirt, green on grassy areas and on some stages, the white snow. The ruined cities are modelled fairly well, without any unattractive textures or major ‘jaggies’. The odd clipping issue here and there with walls can be noticed, but isn’t a major issue. Frame rate is another area where the game periodically disappoints. During some action-packed combat scenes the frame rate can slow down to a very noticeable point. This doesn’t happen all the time though, as you can have a fight with up to six other enemies and the game will be running at a smooth frame rate the whole time, whereas there are some times when you may be fighting only one soldier and the game will slow right down. Jesper Kyd is in charge of the sound for Robotech: Invasion, and its actually pretty good. There doesn’t seem to be a lot of different tracks for the music, but its barely noticeable, as it fades into the background sounds and occasionally gives you that little bit of urgency or triumph. The music seems to suit the Robotech game, being of a futuristic type theme. Voice-overs could always need a little bit of polish and shine, but overall they aren’t too bad. "The game just doesn't feel like a well oiled machine" - Robotech: Invasion Relevant Articles Comments Comments (0)
dclm_baseline
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Hops in the mash. Hops in the empty kettle. Hops in the full kettle. Hops at flame out. Hops in the whirlpool. Hops with the yeast. Hops after fermentation. Hops before cold crashing. There were alot of hop additions in this beer and every single Columbus addition has added a layer of that stereotypical west coast flavour. Enjoy fresh. Enjoy often.
mini_pile
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Privacy Policy Sown In Thorns And Raised In Lilies You are risen. You are risen indeed. We are going to look at, in just a moment, the incredible idea of the reality of the resurrection, as you come to your truth, as is lived for the first time the reality of you in your maturity, in your coming into your new sense of consciousness. If you really stop to think about it, of what significance would the resurrection, or ostensibly the resurrection, the overcoming of death of the carpenter two thousand years ago in Nazareth, have possibly to do with you? Yet in reality, if it doesn’t finally have to do with you, it has nothing to do with anything. Nothing has ever occurred in what we would call the realm of space/time consciousness that did not have directly to do with you as you are at this moment, as you think of yourself. And, in fact, it has nothing at all to do with anything, except it directly pertains to your state of consciousness in attempts to identify the sense of beingness that you find yourself in at this moment. The true value of everything that has ever occurred, historically, in what is defined as history, or cause and effect, or relationships in fracturedism, have finally only to do with you now, at this moment, in regard to how it is re-cognized in your individual system of identity. As I sit here with you, I have a perfect recollection of what occurs in the death process, of what happens when you die. I could give you very explicit details in regard to examination of the bardo, the feelings of the occurrence of the death and awakening process. The incredible sudden realization that there is no turning back at the time you enter the portal. The sudden determination to see it through at that point and retain identification of it, in the total abandonment of the process. The peace that passeth understanding, the ordeal is over and you come into the truth of recognition that you are still here, your still alive. The glory of the light that you behold and truth that comes about in you. Jesus, in A Course In Miracles, says, and I won’t be quoting: I gave you a rather graphic demonstration of the idea that there is no death. And the energy influx at that time, space/time, which was just a few days ago, really, in reality, has been with you ever since. It came in the formulation of Pentecost and is now contained in your genetic memory. It is impossible, as you are here at this moment, not to remember the occurrence of two thousand years ago, because you are constituted only in memory. That’s literally all that you are. Your forbears remembered you and conceived you, and made you in the image of themselves in limitation and thus it has ever been, since the occurrence of the schism. You are Adam’s dream. You are your own dream. The effects that appear outside of you, you have constructed. “Are you saying to me then that the man Jesus made up - okay? - within his limited framework of consciousness the crucifixion and resurrection?” Of course he did. Of course. Is that a little tough for you? He says in A Course In Miracles, “I wasn’t real, as I was identified and as I identified myself I was not real.” Amazing, isn’t it? So what do we celebrate at Easter time? We celebrate the overcoming of death, or the recognition of the specie as identified man on the planet earth being in fact a god. “Know ye not that ye are gods?” “Greater things will you do than I have done.” What are you waiting for? The determination of the identification in limitation to hold onto selfness and literally construct murder and greed and hate and anger have nothing at all to do with you, brother. You have a single assignment here, and that’s to come to your own individual Atonement, and none other. That is your sole function in consciousness. And that’s what you are coming to know. Did you then die on the cross and were you in fact in the tomb for three days and did you rise again? Of course. Shall I do an analogy in your body of what occurs glandularly during that process, so that I can bring you into this moment rather than have you remain historic in identification of it? What’s the difference? You are all memory anyway. This is the time when you do it. This is the time when you remember, when the ancient melody plays for you. This is the time when the incredible joy of the recognition of your eternity flashes across your mind. And you will at that moment pay no longer any direct heed to anything that occurs on earth. You will simply subtract it; you will see the unreality of it. It’s a momentous occasion that is applauded in Heaven, as each of you individually comes into that truth. We await your homecoming. Everybody else is home. Just you linger. All of the things that you have constructed outside of you in your projections in order to retain this false identity, Lucifer, are not real. There is only one Son of God and it is you, prodigal. What are you waiting for? Are you waiting for something, something outside of you that is in your memory banks to somehow show you the way? They can, they can. They’re just your thoughts, your limited thoughts in consciousness. You have created indeed, but you have created falsely because you are false to yourself. He is risen indeed. He is risen. As He says in A Course In Miracles, the earth is literally not here. It was repaired the moment that the schism occurred. And you actually, in reality, have never left home. No wonder you get these stirrings in you that somehow you don’t belong here and you’re not here. You’re not! That’s nice to know. He is risen indeed. You have risen indeed. If you are in responses, where you’re in your path, where you’re in your Bethlehem, where you’re in a temple, where you’re teaching, where you’re in your Gethsemane. Be there. That’s okay. You have risen indeed, brother. “My Lord, why hast Thou forsaken me.” You live with that, literally, on a moment by moment basis. “Father, into Thy hands I commend my spirit.” “It is finished.” Ffffwwwwwssssst! It’s gone. I am interrupting your dream. You are beginning now to have difficulty locating me. You are beginning, in your own consciousnesses, to extend from you your own identity, through recognition of the light. Wow! What a strange notion that finally you’ll never be able to locate yourself. Can you feel this? I have absolutely no idea where I am, because I am not anywhere. It may appear to you, now as you project me, that I am somehow sitting here in a place in space/time and that you will retain identities. I am not. I am not here. Huh, why would I be here? You’re not here either. [laughing] The highest truth - Jesus talks about this in the Course too - the highest truth I can give you is when you come into true conception, or an idea about yourself, you’ll see obviously you could not be located anywhere. Where would you locate yourself outside of truth? You couldn’t. Do you know what I am really saying? I am you. Consciousness, the state, Dharma, in the universe - all of it is consciousness - only has one manifestation of awareness, or Son, that has been caused by Him to establish causation, and that’s you, in your consciousness. There isn’t anything else but that. You are risen. You are risen indeed. Be of good cheer. You offer your brother lilies now, not thorns. As you share that gift of gratitude and love with him, he will extend back to you the truth of you. In that forgiveness are you made whole. One little idea of total love, carried to its completion, transforms the world forever and has. That’s the power of your thoughts, Son of God. You cannot use it in limitation, but only in the truth of your extension, because it is literally your creative capacity. And your misuse of it, and your inability to extend it from you, are what cause pain and death. True. You die because of your attempts to hold on in limitation, to grasp and keep separate from the truth, yourself. Creation and love depend on flow. The Sea of Galilee thrives, it has outlets. The Dead Sea is dead; everything flows in and nothing comes out. All humans on earth as constituted are Dead Seas. They have no outlets. They have no communication processes. They communicate only with themselves and have no reality in truth. Because love is communication. Love is recognition of yourself in love and purity. So you have been fishing off the wrong side of the boat, haven’t you? Ha ha, nice analogy. Yes. Yes. Some of you had some high recognitions and decided to go back to Galilee and fish anyway. We don’t talk much about that. Peter? Come to your truths. It’s all in you and it’s all lovely. You walked that seven miles, huh? You passed your Palm Sunday? You are born in your lower regions; you’re coming into your truth. You have passed your heart and compassion center, and you have moved very rapidly up to your prophesying ability. The raising of Lazarus is man’s love for man, not Godly. You brought about your crucifixion, and Golgotha in your head, and your enlightenment in your crown. As you come to the glory of your reality. Astonishing, isn’t it? Happy Easter. Excepts from Sown In Thorns And Raised In Lilies From The Return of the Heretic Series Sown In Thorns And Raised In Lilies
dclm_baseline
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Boxwood - Preserved Write a Review A staple throughout Roman times, the European Renaissance, and Colonial Gardens, Boxwood is truly a classic foliage. This dyed and preserved version will bring a lasting touch of that classicism to your home. measures approx. 18" Dried and preserved flowers and foliage are affected by moisture, humidity, high heat and direct sunlight. For longevity, these are best kept indoors. Please refer to our FAQ page for more details.
dclm_baseline
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options idea... You sell 10 contracts of june 12.50 calls at a price of 1 dollar each. You buy as a hedge 10 contracts of july 12.00 at a price of 1 dollar each. ideally the stock goes up a little, down a little but thats about it. the options you sell expire and you sell your hedge and your profit starts at 100% and goes down depending on how much your long hedge position depreciated. If the stock takes a jump you will always be ahead b/c your hedge position is closer to the money and a month away from expiration. If the stock dives to 0 your hedge becomes worthless, but of course so do the options you sold. So you dont gain or lose. The biggest question of course is how could the june 12.50's be going for the same price as the july 12.00. My answer is that they SHOULDNT be, but if you found a case in which there was this kind of price discrepency...wouldnt this work? It may appear as though you can buy this diagonal spread for zero, but if you try you will no doubt find it was a mirage. To buy a call spread in the same month for zero - that would be more than unlikely. To buy one where the lower strike (buy leg) had a month more time remaining than the short leg - well, you can pretty much forget about it. If it turns out that I'm wrong, please come back after the fact and let us know. I'd love to discover that such mispricings are still possible. It may appear as though you can buy this diagonal spread for zero, but if you try you will no doubt find it was a mirage. To buy a call spread in the same month for zero - that would be more than unlikely. To buy one where the lower strike (buy leg) had a month more time remaining than the short leg - well, you can pretty much forget about it. If it turns out that I'm wrong, please come back after the fact and let us know. I'd love to discover that such mispricings are still possible. More... Ok I just wanted to make sure that the main problem with the scenario is the misprice. I will tell you that they are out there. I've never found one that was trading at 100%, but ive found 3 or 4 that we're trading at 90%-95% despite being $1 further from the strike and a month closer to expy. What would you do if you found such a case?
mini_pile
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You are here Member since April 2003 Easy Rice and Black Bean Burritos What you need:  1 cup instant brown rice 1-2 tablespoons cumin seeds 1-2 tablespoons chili powder oregano, to taste oil, as needed 4-6 large cloves garlic 1 large onion, diced 1 medium-large green bell pepper, diced 1 bunch fresh cilantro or parsley, chopped 1/2 cup prepared salsa 1 can (4 ounces) chopped green chiles or 1/4 cup pickled jalapeño slices 1 can (15 ounces) black beans, drained and rinsed salt and pepper, to taste 10 flour tortillas 8 ounces vegan cheese, shredded 1/2 head lettuce, shredded What you do:  1. Cook rice according to package directions. In a medium-large skillet, toast cumin seeds and chili powder over high heat tossing or stirring constantly to prevent burning, until fragrant and lightly toasted (about 1-2 minutes). Remove to small dish and set aside; add oregano. 2. In same skillet, heat a few tablespoons olive or canola oil. When hot, add garlic, onions, and peppers and fry 2-3 minutes over medium heat. Be careful not to burn garlic and onions. They should retain their crunch. 3. Add cilantro, salsa, chiles/jalapeños, hot cooked rice, drained beans and reserved spices to skillet and heat through. Taste and adjust seasoning. Add salt and pepper, to taste. 4. Gently warm flour tortillas in oven according to package directions. Do not overheat or they will dry out, making folding impossible. Spoon a bit of the bean and rice mixture on each tortilla and top with cheese and lettuce. Fold burrito style and serve. Preparation Time:  Under 30 mins Cooking Time:  Recipe Category:  Be the first to add a comment. Log in or register to post comments
dclm_baseline
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April 14, 2010 With healthy feet, Gilreath hopes for big year MADISON - As a freshman, it didn't take long for wide receiver David Gilreath to open some eyes with his blazing speed and kick return capabilities. But after a somewhat slower sophomore, Gilreath looked to bounce back as a junior. However, with a couple of very sore and bothersome foot injuries plaguing the speedy runner throughout the season, Gilreath wasn't able to perform at his highest level. Now, as spring camp winds down, Gilreath has a fresh pair of feet. With them, the senior wide out hopes to accomplish great things during his final go round with the Badgers. At the conclusion of a recent practice, BadgerBlitz.com caught up with the Minnesota native. The following is a question and answer with Gilreath. Obviously with spring camp winding down, has it been going pretty good? Gilreath: Yeah, it's going pretty well. It's always good to get it done with. I love football and everything, but you want a break sometimes. How are you doing with your feet? Gilreath: They are back to normal. I feel some soreness in there, but it's fine. Did you have any surgery or anything during the off-season? Gilreath: This past off-season? No. How bad were they hampering you last year? Gilreath: Yeah, I had surgery a couple of months before fall camp started. My first day of actually running was the first day of fall camp. I got out there and I started grinding right away. With an injury, even though you may try to baby it, it just never got better. I just kept pounding it and it got worse. I just had to play through it basically. When was it the worst? When you went side to side? Gilreath: Yeah, coming out of breaks it just bothered me. It's your feet and it's on both sides. You try to limp on one, but when you limp with that one you're kind of hobbling. It was kind of funny, but it was both of them so it was pretty tough. You said they get a little bit sore now in spring camp, but are they comparable now to what they were last season? Gilreath: No, this is just like a soreness. It's all good. The other ones were just a sharp pain and it was pretty intense. I had never dealt with anything like that before. It's got to be a relief then if you're feeling pretty good with the feet, especially as a receiver. What can you do with healthy feet? Gilreath: I hope I can put the last couple of years together. I had a good returning year, a decent receiving year and good rushing year. Hopefully I can put it all together for a big senior year. You talk about yourself, but as a unit you guys have a lot of guys returning with a lot of experience. How good can you guys be and how do you get to be that good? Gilreath: You've just got to work hard. I guess we can't settle for what we've done last year. We can just springboard off of that and try to snowball off of that. We do have a great team and I think that Miami game really gave us some confidence. We can beat anybody. We beat the U, a highly ranked Miami team, that wasn't just a slouch team. We went out there and won. I think we can snowball from that. We've got a lot of great players from each position. How about the offense in general? It's just loaded this year it seems. Obviously you lose Garrett Graham and Mickey Turner, but you guys have got a lot coming back. Gilreath: Yeah, but it happened my freshman year when I came in here. They were talking about having a lot of guys coming back from that 12-1 year, this and that. The guys talk about that a lot out here. We haven't done anything this year. The 12-1 year was great, the 10-3 Miami team was great, but we have to come out here and work hard. They're pushing us in practice. I feel like they forgot about that and they're pushing us out here. Is that a mentality that the coaches instill or something that you guys as players are trying to strive for too. Just within your own circles? Gilreath: I don't even think coach has talked about us last year much. I think it's the players. We had a senior meeting and we talked about it. We can't settle for anything less, and I think somebody mentioned the 9-4 year we had after the 12-1 year. We've just got to forget about that. I think coach Bob Bostad had a speech. He's a real rah-rah guy and he kind of cussed us out, but he had a real good message. It was about forgetting what we did last year and keep going forward from that. That's got to be a motivating factor. Did he just fire you guys up? Gilreath: Yeah, he's a great motivational speakers. It's not just one of those speeches where you're like, 'Okay, that was a nice little speech.' I thought he put feeling into it and we understood where he was coming from. He talks with a lot of passion and we know what he's talking about because he's a great coach. He yells a lot, but whatever way you want to get your message across we're going to respect you. Talk about yourself a little bit. You're kind of the staple of that end around play, what makes that work? Gilreath: The blockers really. Anybody can come flying around the corner. We can get Isaac Anderson or Nick Toon flying around the corner. Maybe they don't have the quickness or speed like me, but hey (laughing). I think we get a lot of guys blocking. Coach Paul Chryst draws up some nice little schemes for it, some blocking schemes. They draw us a nice little scheme for it and it works pretty nice. A lot of people don't use it. I think we got it from Oregon State or whatever. I see them using it a lot. They drew up a nice little thing. That's what works pretty well. You obviously like running it. Gilreath: Yeah, just touching the ball in general. Keeping the ball on offense is fine.
dclm_baseline
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Past Fellowship and Scholarship Recipients Skip Navigation Past Fellowship, Scholarship, and Grant Recipients Each year, we have a number of students receiving a variety of national fellowships, scholarships, and grants. If you are considering applying, you may find it helpful to explore their examples.  Andrew Kostic '08 Applied in Academic Year 2012–2013 (More recipients will be announced soon!) Critical Language Scholarship (CLS) The CLS is a program of the U.S. Department of State. It offers intensive summer language institutes in 13 critical foreign languages. David Esber '13 - Arabic "This summer, I will be studying Arabic in a country in North Africa or the Middle East as a recipient of the Critical Language Scholarship (CLS) program. David Esber '13 CLS Recipient After meeting and networking with CLS participants and alumni in the Washington, D.C., orientation, I will join a study program in Oman, Egypt, Jordan, or Morocco to push my fluency with Arabic toward a diplomatic level. To more fully immerse myself with the language and culture, I plan to stay with a host family. As a Peace and Conflict Studies major, I relish this opportunity to extend my proficiency in Arabic as I prepare for a career in International Relations focusing, hopefully, on some aspect of the Middle East." Coco Vonnegut '13 - Hindi "This summer, I will be in Jaipur, India, on a Critical Language Scholarship to study Hindi. In addition, I will meet prominent academics and officials from local institutes. Coco Vonnegut '13 CLS Recipient I am so excited to return to India and build upon everything I've learned at Colgate. India has been my regional focus of the Asian Studies major at Colgate and I am currently working on a thesis about nationalism and Calendar art. I greatly look forward to continuing that work by completing the short Independent Study facilitated by the program." Watson Fellowship The Watson Fellowship is a $25,000 award for independent exploration and travel on a topic of interest to you outside the United States for one year after college graduation. Srikar Gullapalli '13 I have been fascinated with the political dialogue between citizens and government since I began representing at international debates. I was selected as a "Global Changemaker" by the British Council because I believe dialogue is essential for government to be a force of good. Srikar Gullapalli '13  As a Watson Fellow, I will travel to Australia, Venezuela, United Kingdom, Egypt, and Russia. I wish to understand local political accountability structures and local citizen-government relationships at the city and community level in drastically different governance contexts. The local level is most important for public welfare and where most corruption and inefficiency occurs. This is the level that citizens can hold accountable and have the most impact on through political dialogue and innovations in social activism. I will conduct interviews of citizens, NGOs, media, local officials, and politicians. I will be a part of town halls and protest rallies, and will engage with students. Rebekah Ward '13 Besides my passion for social justice, I have an academic and personal fixation on communication and identity. I have a pressing need to work to ensure equality and to fight for the rights of marginalized people. Rebekah Ward '13 Roma ("Gypsies") are one of the most widespread minorities in the world. They have no nation or homeland, and have a history of marginalization across the globe. Since childhood, the Roma story has guided my passion for social justice. As a Watson Fellow, I will travel across Europe and then to Brazil, where a recent wave of Roma have settled, attempting to understand how Roma groups communicate their culture and how the tensions and challenges of this endeavor vary depending on state laws and rhetoric. I will also meet with Roma activists globally to learn what drives their dedication. NIH Intramural Research Training Award (IRTA) The IRTA provides an opportunity for developmental training and practical research experience in a variety of disciplines related to biomedical research, medical library research, and related fields.  Brian Lemanski '14 DAAD Summer Course Grant This program funds a three- to four-week summer course at a German university which focuses mainly on German language and literary, cultural, political, and economic aspects of modern and contemporary Germany.  Christopher Wendt '13 American India Foundation (AIF) Clinton Fellowship This fellowship offers 10 months of field work in India to gain knowledge of development on the ground in fields of education, livelihoods, public health, and social enterprise.  Coco Vonnegut '13 Applied in Academic Year 2011–2012 The U.S. Student Fulbright Grant Program One year to study, conduct research, or teach in one of 150 countries Kathryn David '12 - Ukraine Katie’s research project is titled “Rebuilding Jewish Community in Odessa.” Odessa is historically recognized as an intellectual, cultural, and religious center for the world Jewish community. Through immersion within the community, contacts at the Odessa Literary Museum and Moria archives, and a formal affiliation with I.I. Menchikov Odessa National University, Katie will research and examine how the Jewish community is rebuilding itself after the fall of the Soviet Union. She is a history and Russian studies double major from Baltimore, Maryland. Andrew Lorraine '12 - Slovakia Andrew will teach at the secondary level, helping students develop their writing and conversational skills as well as an understanding of American culture through an engaging and interactive classroom. During his Fulbright year, Andrew plans to explore his own Slovakian heritage while learning about the history and geography of the Slovak Republic. He is a political science major from Penllyn, Pennsylvania. Lauren Shively '11 - Taiwan Lauren will teach English language and American studies, and in turn gain a greater understanding of Taiwan’s educational system and culture. She embraces the grant as a cross-cultural exchange, with plans to fully integrate herself into the community for which she is placed through educational and extracurricular experiences. She is an English major and history minor from Wayland, Massachusetts. Josh Smeltzer '12 - Germany Josh will teach English at a German High School where he plans to focus on using experiential learning to add an interactive dimension in the classroom. Josh will extend his own learning and gain a deeper understanding of German history and culture through full immersion within the community. He hopes to create or join a book club and volunteer. He is a peace and conflict studies major and German minor from Hillsboro, Oregon. French Ministry of Education One year French Government teaching assistantship in France initiated through the Fulbright application process Catherine Murray '12 - France Catie plans to serve as a resource to students as they advance their English language skills and learn about American culture. She is eager to start an English club where students can practice their language skills outside of the formal classroom. As an ETA, Catie wishes to contribute to the increased global understanding of her students. She is a peace & conflict studies and French double major from Lancaster, New York.
dclm_baseline
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Photographic (or other optically captured images) images may be blurred by relative motion between an imaging system or camera and an object of interest. An example of a motion-blurred image is illustrated in FIG. 1. Motion-blurred images commonly occur when the imaging system is in moving vehicles or held by a human hand. OCR of blurred text of blurred text may be inaccurate or in some cases may be impossible. The methods used to restore such images typically involve convolving the real image with a point spread function (PSF): g ⁡ ( x , y ) = ∑ k = 1 K ⁢ ∑ m = 1 M ⁢ f ⁡ ( k , m ) ⁢ h ⁡ ( x - k , y - m ) + n ⁡ ( x , y ) , ( 1 ) where f(x,y) is the non-blurred image; g(x,y) is the image obtained from the camera; h(x,y) is the PSF; n(x,y) is the noise; and K and M is the size of the image in pixels. In the case of a blurred image, the PSF is a function of one argument, i.e. h(x,y)=h1D(x sin(α)+y cos(α)), where α is the angle of the blur. In the Fourier space, the equation (1) becomes: G ⁡ ( p , q ) = F ⁡ ( p , q ) ⁢ H ⁡ ( p , q ) + N ⁡ ( p , q ) , ⁢ where , for ⁢ ⁢ example , ⁢ G ⁡ ( p , q ) = ∑ x = 1 K ⁢ ∑ y = 1 M ⁢ ⅇ 2 ⁢ π K ⁢ ⅈ ⁢ ⁢ px + 2 ⁢ π M ⁢ ⅈ ⁢ ⁢ qy ⁢ g ⁡ ( x , y ) ⁢ ⁢ and ⁢ ⁢ g ⁡ ( x , y ) = 1 K · M ⁢ ∑ p = 1 K ⁢ ∑ q = 1 M ⁢ ⅇ - ( 2 ⁢ π K ⁢ ⅈ ⁢ ⁢ px + 2 ⁢ π M ⁢ ⅈ ⁢ ⁢ qy ) ⁢ G ⁡ ( p , q ) . ( 2 ) Since the function G(p,q) and the others are periodical G(p,q)=G(p−K, q)=G(p,q−M), it is assumed everywhere below that the p and q variables may have either positive or negative values. H(p,q) is the Fourier transform of the PSF, often called optical transfer function (OTF). In the case of a blurred image, the OTF is a complex function of one argument H(p,q)=H1D(p·sin(α+π/2)+q·cos(α+π/2)). Also, the Wiener filter may be used to restore images: F ^ ⁡ ( p , q ) = H * ⁡ ( p , q )  H ⁡ ( p , q )  2 +  N ⁡ ( p , q )  2  F ⁡ ( p , q )  2 ⁢ G ⁡ ( p , q ) , ( 3 ) where {circumflex over (F)}(p,q) is the estimated function (which hopefully is close to F(p,q)) and H(p,q) is the complex conjugate of H(p,q). This filter minimizes the root mean square deviation of the restored image from the real image ∑ x , y ⁢ ( f ^ ⁡ ( x , y ) - f ⁡ ( x , y ) ) 2 ,provided that the average noise value is 0. Therefore, in order to restore a blurred image, one needs to know: 1. the OTF H(p,q), and 2. the signal-to-noise ratio in the impulse space  N ⁡ ( p , q )  2  F ⁡ ( p , q )  2 . U.S. Pat. No. 6,470,097 Oct. 22, 2002 describes an iteration method for finding a non-blurred image. At each step of this method, total variation regularization is performed to minimize the energy function with the image blur. The type of distortion is set as a parameter and is predefined. The length of the blur and its direction are also predefined. Additionally, the image is restored from a sequence of images rather than from one blurred image. U.S. Pat. No. 6,859,564 Feb. 22, 2005 describes a method where the OTF is determined from the scaled αth power of the smoothed magnitude of the blurred image and noise. Other methods for restoring blurred images are described, for example, in the review by D. Kundur and D. Hatzinakos, “Blind Image Deconvolution Revisited,” IEEE Signal Processing Magazine, vol. 13, no. 6, pp. 61-63, November 1996, and in other sources.
mini_pile
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I'm pretty sure there isn't a human being alive on this Earth who hasn't played at least one board game. Quite simply, board games are fun, challenging, and addictive, just like crack cocaine and kidnapping rich people's children. But as simple as they are, board games often imitate reality in epic ways. Chess incorporates elements of military, political, and religious conflict just as Candy Land has candy, and everyone loves candy. With all that jibber-jabber said, the Something Awful Forum Goons set out to turn things around by combining classic elements of board games with reality. The results were both odd and odd, or odd squared. We're finally back after last week's mysterious hiatus! Before I get things going, I want to thank Worth1000.com for sponsoring this week's Phriday. If you fancy yourself a connoisseur of Photoshop tomfoolery, give them a try and a half. They've got a lot of great talent and cool contests going on daily, so it's well worth your clicking. Board games mimic life, yes, but now reality imitates board games! As usual, the Something Awful Forum Goons got all whacked up on PCP and whipped out a unhealthy slew of images among other things. I got things started with a little Battleship action: "ManiacClown" fires some heavy weapons. Hey, that bastard sunk my battleship! "SenatorASSFACE" didn't get my vote, but this image sure does: "RipVTide" learned geography from losing at Risk: "NotJust4Breakfast" wants to go to Iraq or something: "GoatRearEnd" could probably benefit from jumping out of a plane: More Photoshop Phriday This Week on Something Awful...
dclm_baseline
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In January 2013, two athletes sexually assaulted a co-worker and teammate. The three members of the Lloyd Irvin martial arts academy ran into each other at a New Year's Eve party at a nightclub. One teammate had too much to drink and didn't want to drive home. The others offered her a ride, but instead of bringing their teammate back home, they attacked her in a parking garage. The assault is described in detail in the criminal complaint filed against Matthew Maldonado and Nicholas Schultz. The police could produce a gruesomely detailed narrative because security cameras in the parking lot recorded the whole thing. One of the least horrible passages, via Zach Arnold of Fight Opinion: Advertisement The Complainant then pushed Defendant Schultz off her as her body slumped to the ground with her head still against the wall. Defendant Schultz then advanced toward the Complainant and began to lie on top of her. Defendant Schultz again pulled the Complainant towards him, holding on to her until her body collapsed again, this time her head striking the ground. As they assaulted their teammate, she fell over, asked that they stop, and hit her head on the ground and against the wall. When they finished, the two men left their Brazilian jiu jitsu (BJJ) teammate unconscious on the parking lot pavement. It was 38 degrees. There she lay until someone walking by heard her cry for help. Schultz and Maldonado had offered her a ride home; instead of looking after a person they saw just about daily at their gym, they attacked her and left her for dead. As one member of the BJJ community put it, they left her there like she was a piece of trash—which is, of course, exactly how other people in that community have talked about her. When this story broke, it quickly came to light that in 1989 the man running their gym, Lloyd Irvin, had been charged with rape. He'd participated in a gang rape—most of the men involved went to jail. Because he didn't have intercourse with the victim, this man did not. This past week, in spite of video evidence of the assault, a jury acquitted the two men of kidnapping and first and second degree sexual assault. A mistrial was declared regarding a misdemeanor charge against Schultz. Over the past year, the leader of this gym, the man who'd escaped the rape charge in 1989, has scrambled to try to paper over the scandal of his conduct—much of this story has been acted out through social media, and much of his behavior has only served to confirm him as an abusive coach. People in the Brazilian jiu jitsu and martial arts community have been doing serious soul searching: a public conversation about rape, violence, aggression, and power began almost as soon as the story broke. Aaron France, a D.C. police detective who is also a BJJ coach, addressed the case in a Facebook post that has since been shared widely on Reddit and on blogs. He attended as much of the trial as he could, and saw the video evidence. When Maldonado was acquitted, some people were eager to celebrate this as a declaration of his innocence. France writes: Ask yourself; if this happened to your wife, your daughter, your girlfriend, your sister, or even a close female friend, would you advocate Maldonado's innocence? Most of you would be calling for blood. Some of you would even take it yourselves. So if we were to look at Maldonado's behavior, put criminal implications aside and give him the benefit of the doubt, here's the best thing we can say about him… He had sex with a woman who was intoxicated to the point where she could not walk, and afterwards he treated her like a piece of trash, by leaving her half naked on the cement floor of a parking garage, in the middle of the night, when it was barely above freezing. And that woman? She was his "teammate." Not many people outside of the Brazilian jiu jitsu Community can comprehend the bond that develops between training partners, due to the level of trust that training partners are required to develop in each other. …Yet there are a few people who believe that we should let him back into the Brazilian jiu jitsu community. These people believe that he should be allowed to continue to sharpen his skills, learning to choke people and cause their joints to stop functioning. They apparently believe that he should be allowed to do this in the presence of women and children. How can you possibly ever trust this man not to just hang onto a choke, or not hold an armbar after you tap? He's already demonstrated a propensity to do what he wants with another persons body, why should we believe it ends with sex? That statement is preceded by a sobering account of the steps required to bring a rape case to trial. That it reached that stage at all, he explains, has to be valued as a certain small measure of justice. Juries—here he cites the Rodney King verdict—don't always get things right. He reminds his readers that people who commit sexual assault pose a danger to everyone around them. It is wrong, he points out, to assume that the violence of their behavior towards a woman is somehow unique to their relationships with women. It is evidence of how they treat people. Martial arts students are physically vulnerable to each other; an irresponsible training partner will hurt the people in his world. Two Gracie brothers—members of the first family of Brazilian jiu jitsu—posted a sincere and thoughtful discussion of the crisis to their popular Youtube channel in January. In that discussion, they emphasize the challenge of martial arts training: it can either produce a balanced, peaceful athlete, or an aggressive and antagonistic one. They also stress the vulnerability of training partners—not women, mind you, but all of the people with whom you study a martial art. The story of the abusive environment cultivated by Lloyd Irvin has scarcely left the MMA bubble, however. If it were not for the work done at Bloody Elbow, I'm not sure this story would have any presence at all in sports media more broadly. It surely deserves much more attention than it's gotten. It deserves attention in part because the victims, the abusers, the bystanders and the defenders were all teammates and training partners. There are few sports communities in which such a thing is possible. And to outsiders, such a thing is truly remarkable, given the nature of the sport we are talking about. In the U.S., young women grapple against young men in high school competition, and those women expand their training into BJJ, boxing, Muay Thai, and MMA. Men can get used to training alongside and sparring with women pretty quickly, and people enjoy having women compete on the same card as men, representing their gyms in team competition as well as amateur and semi-pro competition. Martial arts competitions are heterogeneous—men and women are both a part of the sport spectacle. They are fans, athletes, trainers, and referees. As authoritarian and hierarchical as gyms can be—and by all reports Lloyd Irvin's gym was and is a frightening example of that—they can also, as Hall writes, be something else. A gym can be a place of humility and respect, a socially level space in which people commit to supporting each other as they attempt to figure out their goals, and help each other to meet them. This assault represents a crisis within the martial arts community not because it seems to express a form of masculine aggression latent in the sport (which is how we tend to frame rape cases involving football players) but because it betrays the values that define it. Sexual violence between members of the same community is engineered to either expel the victim from that community, or to make her sexual subjection a condition of her membership. Unlike the women assaulted by football players in the stories that make national headlines, the woman assaulted in this story was not only a fellow teammate; she was also a fellow employee. There can be no assertion that rape culture is somehow endemic or specific to a sport that is desegregated: a sexual assault in that environment is like a sexual assault in any environment in which the victim knows, and has some kind of relationship to, her attacker. It isn't the sexism of the sport that's at issue, it's the sexism of that gym space, and the sexism of the world. These are, in fact, the conditions under which most sexual assaults happen. A person might be attacked by her co-worker, a member of the same military unit, a boss, a teacher. A member of her family. And this holds even in these football stories: these young women are not outsiders. They are, almost universally, fellow students, attending the same high school or university as their attackers. Of course every community must work towards a world in which there is no sexual assault. Every instance makes us ask why and how. With regards the case at hand, we must consider how little justice there is for victims of sexual assault, and how much harder such cases can be for those assaulted by people they know. (Would that jury have acquitted those two men if they were strangers to the woman they attacked? In what world do you leave a consenting sexual partner on the ground outside in the winter when she is too drunk to even sit up?) This case shows us that we need to consider how should we respond to such a profound transgression of the athlete's community. We must work not only to make another attack less likely, but also to embrace the person attacked, to refuse to exile and shame her. To refuse complicity with narratives which make the presence of women within the sporting community into the problem, the "cause." We must make room for conversations about sex, violence, and power. The football-centered conversations about rape just haven't been compelling to me. Too often, such conversations are anchored in a deeply patriarchal language that reinscribes the social vulnerability of women to masculine aggression. And while you will see the shadow of that mindset creep into the Gracie brother's discourse, overall, the conversation that they and Oden and Hall and others have been forwarding is actually centered on the integrity of fighting, as an art that defines a community. At the heart of a fight is a consensual relation to violence. That consensus is not merely an agreement to fight: it is also an agreement to stop fighting when one fighter submits to the other and taps out. Rape is a violation of the bonds of trust and dependence that make this sport even thinkable. Bloody Elbow reported in February that Lloyd Irvin's best fighters left when one of the women on the team confided in a teammate that she'd been subjected to classic harassment that was moving towards sexual coercion. She needed help and advice. In how many sports does a woman talk to a man, as a teammate, about this? That one gesture—in which a junior woman athlete turns to a male colleague—and that one productive response—athletes united in their outrage—demonstrate how things can be. At least within the community of fighters invested in a not-sexist training space, the problem isn't men, and it isn't women. The problem is the sexist, authoritarian leader. That authoritarian figure is as much as a problem for men as for women. There is no such thing as a "rape culture" unique to "jock culture"—it is only (only!) the deep, dramatic segregation of football as a purely masculine space that makes the Steubenville-like stories of social, public group attacks on women feel somehow unique to the sport. I wonder if one attraction to the phrase "rape culture" isn't the way it lets us disavow the fact that gender segregation builds sexual violence into a social structure. You won't find an authoritarian patriarchal space that doesn't in some way produce the conditions of possibility for this kind of attack, a kind of violence that partners well with homophobic attacks on genderqueer people. Making this story all the harder to tell is the ferociousness of public ignorance about sex and power. I imagine that people who join together in sexual assaults against people who are incapacitated (by alcohol, by drugs—sometimes by drugs given to them with malicious intent) are people who would not dare to consider their relationship to eroticism, to sex, and to pleasure. I imagine that these are people who do not know how to participate in a conversation about sex and power. These are people who cannot solicit consent from a sexual partner—they are too afraid to ask even themselves what it is they are seeking in a sexual encounter that is as much with their male teammates as it is against the woman they are attacking. Even in the community of athletes trying to do the right thing, many stay away from the subject of rape, harassment, and sexism. Few know how to talk about it. I end with this set of observations because Irvin's defense of the 1989 assault seems to amount to calling the woman a whore, describing the attack as a group "pulling a train" on a "freak" who then changed her mind. And that's how many people want to think of the New Year's Eve victim. Would these men even know what consensual group sex within a BDSM context even looks like? Of course not. Within the sports media, there is almost no room for bringing a sexually progressive voice to bear on this topic. People who play with those scripts (group encounters, D/s, bondage, etc.) tend to be quite practical about sex, working knowingly towards wisdom, often within pedagogical relationships with more experienced people. It is, in fact, entirely possible to seek out sexual communities that give you something like what a gym promises: A better understanding of one's body, one's desires and ambitions, a social intimacy not bound by romantic/domestic partnership. Sexually progressive folks can be extraordinarily careful about consent and perfectly able to make that carefulness sexy. I wonder: Does the jury that acquitted those two guys have any idea what a consensual three-way looks like? Sex-phobic people may imagine it as people out of their wits going at it in a back alley blind drunk, because no one would dare do such a thing sober so if you are that drunk isn't that what you were looking for? If we can't trust a jury to do the right thing, it is perhaps because a jury of one's peers isn't likely to be able to think through the relationship between sex, power, and violence. This is one of the horrifying things about heteromasculinist, sexist, homophobic, anti-sex spaces. They produce a fantasy of community and collective identity, but at the violent expense of specific bodies. They are driven by a terror of that which they are not, a fear of the bodies against which they define themselves. Sex becomes an instrument for producing specific bodies as socially abject. In the totally segregated universe of football, the communal aftershock is not felt deeply enough. But in the BJJ community, at least within some quarters, this event has led to serious, serious soul searching and an affirmation of the sport's ethos, an interrogation of the power structures that distinguish one gym from the next, and an affirmation of shared vulnerability as not a weakness but a value. A thoughtful relationship to consent and violence is, in other words, built into the sport's heart. This may be one reason why so many women enjoy belonging to this particular sports community. Because on the mat, no really does means no. Jennifer Doyle is the author of Hold It Against Me: Difficulty and Emotion in Contemporary Art and Sex Objects: Art and the Dialectics. She is a Professor of English and Co-Chair of LGBIT Studies at U.C. Riverside, and is the 2013-2014 Fulbright Distinguished Chair at the Center for Research on Transnational Art, Identity and Nation at the University of the Arts, London. In 2012, she was awarded an Andy Warhol Foundation Creative Capital Arts Writers Grant in support of her current writing about "the athletic turn." She is the author of the blog The Sport Spectacle.
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Skip to main content Submit Your Story It's an education that's relevant in every way. It's the advantage that comes from learning with the best minds and in the best organizations. You feel it when a professor shows you how to take ownership of an idea and when an internship, co-op, or research project brings your future into sharp focus. It's the combined power of first-rate academics and first-hand experience-- world-class discovery meets real-world clarity.
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06/04/2015 17:04 BST | Updated 06/06/2015 06:59 BST The Politics Of Style: What Will Make Us Vote This May I have been lucky to work with some of the world's most creative talents - Amy Winehouse and Lady Gaga being just two of them. Being a good hair stylist, whether it's working on a red-carpet or with a client in my London salon, is all about creating a look that makes an individual feel good about them self and enable the rest of the world take them seriously. If people look good and take care of their appearance, we tend to trust their opinion more. When I cut Ed and Justine Miliband's hair a couple of years ago, it was a simple case of sharpening up both their images. They had both gone from the political side lines to the mainstream overnight - they were a bit like rabbits in the headlights. My styling of Justine turned her from "mouse to fashion maven" overnight (that was according to Liz Jones so I will take that!) Ed, on the other hand didn't like the shorter, sharper look that I gave him. I think Ed would really rather be an academic hidden away than a media personality. Since I worked with him, his hair has gone all over the place - one minute its long, then short again - if Ed had a more decisive cut and stuck to it, then people would care less about how he looks (or the size of his kitchen) and more about why we all once liked the Labour Party -they do tend to care about people. The biggest story for this year's General Election will undoubtedly be Nigel Farage: he smokes, he drinks, he wears his green Barbour with pride and he sports the classic middle England middle-class short back and sides. What you see is what you get with Farage - or is it? For Farage the symbols of 'Britishness' makes him safe - unlike say, the BNP. Farage appears to be 'one of us' standing up against 'all of them'. He is a clever operator and so is his look - especially as these days most politicians are scared to make any kind of statement. Politics and fashion are no longer the friends they once were - think of the iconic politicians: from Churchill to Thatcher, even Michael Foot and his duffle coat - they all had a 'look'. You couldn't have Spitting Image today as our politicians have morphed into the same person. They are scared of fashion - more than that, they seem afraid to make any kind of personal statement. This has caused the blandness of politics which is what we all complain about. This is why someone like Theresa May seems to make so much noise. I am not a particular fan of the woman, but because she actually appears to have read a fashion magazine and walked into a decent shop, people seem to like her for being a bit 'different'. A brightly coloured or patterned coat will always be more interesting for photographers and photo editors than yet another dark blue suit. Politicians seem to feel that appearing to love clothes or to groom themselves is a weakness. I believe it will be the SNP party and Nicola Sturgeon who could prove to hold the balance of power come election day. Her new look evolved over the Independence Referendum: the more angular hair cut to the jaw, the rich honey highlights, the darker make up and the slick suits have given both her and the electorate more confidence. Nicola Sturgeon is now a major political and style power-house and her party may indeed end up controlling the outcome of the vote for the UK - not bad for a 'wee lassie in a tin helmet'.
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Posts tagged ‘“Central do Brasil (Central Station)”’ Acclaimed Brazilian filmmaker Walter Salles crafts personal, socially conscious stories that are emotional without being manipulative and simple without being simplistic. Among them: the gritty “Terra Estrangeira (Foreign Land),” the earthy fable “Abril Despedacado (Behind the Sun)” and “Linha de Passe,” which earned Sandra Corveloni the best actress award at Cannes. “Central do Brasil (Central Station)” collected dozens of prizes and received Oscar nominations for best foreign-language film and lead actress (Fernanda Montenegro); “Diarios de motocicleta (The Motorcycle Diaries),” the story of a cross-continental trek that shaped Ernesto (Che) Guevara, was an international hit and major award winner. The 54-year-old, twice a BAFTA honoree, will receive the Founder’s Directing Award on Thursday at the San Francisco International Film Festival. Q: Your films tend to be set in specific sociopolitical circumstances.(more…)
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AMERICANS, opined Barack Obama near the beginning of his state-of-the-union address, do not expect their politicians “to agree on every issue”. Nonetheless, he continued, “they do expect us to forge reasonable compromise where we can.” That is not just a fine sentiment: with Republicans in control of the House of Representatives, Mr Obama will have to do some haggling to get any of the elaborate agenda laid out in his speech adopted. Most urgently, a compromise will be needed if America is to escape the “sequester”, a big package of spending cuts due to take effect on March 1st, but designed to be so extreme that Congress would never actually allow them to occur. Yet finding that compromise looks harder than ever. Mr Obama proposed much the same formula to reduce the deficit and avert the sequester as he has previously, though never in so elevated a forum. He offered to allow substantial cuts to Medicare, the government’s health-insurance scheme for the old—something most Democrats resist. In exchange, he said, Congress should raise revenue by eliminating loopholes and deductions in the tax code. Tax reform is something that Republicans have generally been in favour of. This is the deal that the two parties were groping towards at the end of last year, in an effort to avoid not just the sequester but also big tax increases for all Americans that were scheduled to take effect on January 2nd as George W. Bush’s tax cuts expired. In the end, however, with no agreement reached by the end of the year, Republicans reluctantly agreed to around $620 billion in tax increases on the rich over 10 years without any accompanying cuts—something the president made only a passing acknowledgment of when calling for further revenue. Instead, he couched his proposal in the language of his re-election campaign, again casting himself as the defender of the middle class and Republicans as handmaidens of the rich. His opponents, he implied, wanted to force “senior citizens and working families to shoulder the entire burden of deficit reduction while asking nothing more from the wealthiest and the most powerful.” The Republicans have repeatedly ruled out further tax increases, possibly because they feel aggrieved that they have appeared to be the big losers in the year’s end deal. In fact, though, in earlier rounds of negotiation, they had secured ten-year spending cuts worth almost three times as much as the $620 billion in tax increases, so overall, the balance of spending cut to extra tax revenues is strongly in their favour. Huff and puff though they will, a solution to the problem of the sequester based on what the administration is still proposing is not a bad deal for them. Whether they will take it is quite a different matter. The budget aside, there were a few proposals that should appeal to Republicans, most notably the launch of talks on a free-trade agreement with the European Union and a renewed push to reach a deal on the transpacific Partnership, a proposed free-trade area involving ten other countries on the Pacific Rim. On the one subject where bipartisan talks do seem to be making progress, immigration reform, Mr Obama was careful not to offend anyone, although his outline of a potential deal omitted a guest-worker programme, something Republicans are keen on. He also offered stern words for North Korea and Iran, and promised to “stand steadfast with Israel”—although that will not be enough to quell Republican complaints that he is hard on America’s allies and soft on its enemies. Explore our interactive map and guide to the stats of America However for the most part Mr Obama packed his speech with ideas Republicans hate. He urged Congress to forswear threats to shut the federal government down or stop paying America’s bills, both cherished Republican negotiating tactics in fiscal disputes. He made an impassioned plea for stricter gun laws, invoking a series of recent massacres and pointing to the parents of a recent shooting victim, who were sitting in the gallery next to his wife. He talked about making it easier to vote, not a popular cause on the right. He demanded that Congress pass a cap-and-trade bill to curb global warming—absolute anathema to most Republican lawmakers—and then threatened to pursue the same goal by regulatory fiat if it did not. On top of all this came various proposals which, while desirable in themselves, all cost money. The president said he wants to ensure universal access to pre-school teaching, to expand vocational training in high school, to set up a network of institutes promoting manufacturing and to create a tax credit for hiring the long-term unemployed, among other new schemes. All of this, he promised, would not add a dime to the deficit, although he provided no details of how it would be paid for other than by reallocating existing spending. Marco Rubio, first responder Republicans immediately pointed out that the public debt has grown by 58.6 trillion dimes on Mr Obama’s watch. Marco Rubio, a senator from Florida who gave the Republican rebuttal to the president’s speech, complained that “his solution to virtually every problem we face is for Washington to tax more, borrow more and spend more.” Referring to his own, working-class parents, Mr Rubio rejected the idea that the Republicans were the party of the rich and accused the president of being obsessed with raising taxes. Mr Rubio had a point, but Mr Obama has a much bigger bullhorn. No sooner had he finished his speech than he joined an online call with supporters. He is due to hold a series of rallies over the coming days to press his case. The president appears emboldened by his re-election, and by his success in enacting tax increases in January in spite of Republican objections. He seems to have concluded that the way to get what he wants out of his political adversaries is by rallying public opinion to his side, and that accusing them of coddling the rich is the easiest way to do it. So he is spending much less time courting the Republicans in Congress, and much more in the bully pulpit, attempting to bully them into submission. Democrats like to think that Mr Obama has nothing to lose in the ongoing stand-off over the budget. Either the Republicans back down, and he gets the concessions he wants on policy, or they stand firm, and live up to his portrait of a party willing to bring the country to its knees to get its way. But that strategy ignores the alarming economic consequences of allowing the sequester to proceed. Worse, it more or less guarantees that recrimination and hostility will dominate Mr Obama’s second term, as they did his first, while Congress does the bare minimum to avoid opprobrium and defer disaster.
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Tag Archives: Marine Le Pen Storify: Tragedy in Toulouse and the “Presidentielle 2012” in France 30 Mar By: Gabriela Gonzalez I have been following the French elections, and an event that has shaken the elections and affected the polls is the Toulouse shooting and comments made about Mohammad Merah, the Algerian shooter. Storify is a great tool where you can collect comments from social media, YouTube and other sources and combine them to make one story that includes diversity in opinion and media. I hope you enjoy! (I speak French, but I tried to in the text explain whatever had no translation or subtitles.)
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How To Make Your Air Last Longer How To Make Your Air Last Longer When Scuba Diving By Thomas Gronfeldt Thomas started diving during college and has since been diving over most of the world: Australia, Indonesia, Iceland, France, and many other places. He is a NAUI instructor and a commercial diver, and participates in environmental and archaeological diving projects around the world. For many divers, available air dictates the length of the dive more than any other factor. Now is the time to learn how make your air last longer for longer dives. Your dive ends when your bottom time runs out — at least theoretically. For many divers, though, the dive ends when one or more divers run low on air. The easiest way for many of us to extend our dives is to focus on air consumption. These tips will help you get the most out of your tank. sidemount diving cyprus1. Streamline It’s simple physics: the larger your profile in the water, the more energy, and thus air, you’ll consume. Consider the difference between a bulky semi-truck and a streamlined sports car. In the water, you’ll want to be a sports car. Go over your gear setup and make sure everything is tucked away neatly, creating the smallest possible in-water profile. 1. Leave things behind A number of divers seem to dive with the saying “it’s better to have it and not need it than to need it and not have it” in mind. They bring so much stuff on each dive that it seems like they’re carrying their entire gear bag. Often, they think it’s easier to just clip everything to their BCD than to assess their gear before each dive to determine what they’ll need. There’s some merit to this, but bringing too much gear weighs you down and increases your profile in the water. So bring the things you need and leave behind the things you don’t. And don’t forget to square it all away neatly. 2. Slow down Diving is the lazy man’s sport, someone once told me, and there’s much truth to that. Diving is not swimming, and you’re not really supposed to get your heart rate up. So slow down — and not just underwater. Get into a relaxed mindset even before you get to the dive site; when you start gearing up, don’t rush. Don’t linger on the dive deck unnecessarily, of course, but go about things in a deliberate, calm manner.  Swim calmly and slowly underwater. The more you rush and fidget, the more air you’ll consume. 3. Breathe deeply Note the difference between deep breaths and big breaths. When you tell people to breathe deeply, many people will forcefully inhale, filling their lungs to the brink. A deep breath should be just that, but it doesn’t have to be a big breath. To learn to breathe deeply, lie down on a firm surface, like a yoga mat or a firm mattress. Put one hand on your chest and one on your stomach. Now breathe, but try to breathe in such a way that only the hand on your stomach moves. This way, you’re filling up the bottom of your lungs, rather than the top, which is what happens when only your chest moves. A deep-belly breath replenishes the air in your entire respiratory system, rather than just part of it, as when you breathe from the top of your lungs. 4. Swim shallow An easy way to extend How To Make Your Air Last Longer and dive time is to take full advantage of the traditional multi-level dive profile by starting your dive deep and moving to increasingly shallow water. Here, we consume less air, so simply moving shallower reduces your air consumption drastically, and with that, extends your dive time. If you’re the air hog of a group, you can, to some extent, offset this by placing yourself slightly shallower in the water column than the other divers. And just by making a habit of ending your dive in the shallows, you’ll ensure that any dive you do can be extended quite a bit. 5. Dive more One easy way to improve your air consumption is quite simply to dive more. Most of the above pieces of advice require some practice, so diving a lot will definitely help you master them. Diving more also helps you become more comfortable in the water, which, in turn, helps a lot when it comes to conserving air.
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The definitive guide to South Asian lingo Definition 1 of 1 17 1 Noun. April 7, 2012, Word of the Day Adding an entry for Cricket in Samosapedia is like designing an exhibition for Futbol in the Museum of Contemporary Art in Barcelona. But someone's got to do it. Cricket is a gentlemans' game. Cricket is athletic. Cricket breaks for brunch, lunch, tea, and dinner. Cricket can last from 4 hours, through a whole day, to 5 days. Cricket is strategy, team spirit, and individual glory. Cricket is in the wrists. It's in the footwork. Cricket hero adulation is supreme. Cricket is in cursing the hero's through the TV screen while belting coffee and pakodas from the comfort of your drawing room sofa. Cricket is in the nets. It's in dedication. Cricket is global. But it holds a special special place in the desi heart. It's one of the heartbeats on the street. It does not discriminate. Pot bellied pumpkins can play cricket. Little toddlers with plastic bats too. Cricket terrain is multifarious: a T-junction outside your house, a neighbours' driveway, the park, the verandah, a mud tank or maidaan (field), a woven coir matt rolled out or a well prepared and manicured pitch rolled on with just the right amount of grass to make it interesting. Cricket is examining the pitch condition and mulling over the outcome. Cricket is a new deep red leather ball that everyone in the gang must touch and admire before the friendly inter-school match begins. Cricket is the number 1 team in the universe losing miserably at their best game format. Cricket is pretending to change the squad depending on the weather. Cricket is throwing the game for the payoff. Cricket is an entire nation partying on the streets after a World Cup Win. Never change the game. "Oy, what's the score?" Added 2011-09-05 by Studmuffin Related videos and images
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How Does Humidity Affect Air Pressure? Humidity lowers air pressure by displacing nitrogen and oxygen molecules with lighter water molecules. Differences in humidity can cause storms to form. Humid air also presents challenges to pilots. Water molecules contain one heavy oxygen atom and two light hydrogen atoms, so it weighs less than atmospheric oxygen, which contains two heavy oxygen atoms, and atmospheric nitrogen, which contains two heavy nitrogen atoms. These water molecules force heavier molecules to spread out, which reduces the air pressure. Because they are so light, water molecules tend to rise in the atmosphere, which is why clouds typically form high in the sky. These differences in air pressure cause air to move between different layers, which can eventually cause storms. Most storms form over the ocean where the hot sun heats the water and causes these types of disturbances. Since cold, dry air is denser than warm, humid air, airplane wings have more molecules to displace, which allows them to generate more lift. As a result, pilots need to exercise caution when traveling through areas of high humidity and high heat. Air pressure is even lower at high altitudes, so part of Mexico and other locations with these conditions requires extra caution when pilots take off and land.
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I was a teenager when this first appeared in theaters, and I saw it in Japan. The film's plot wasn't my cup of tea as a high school sophomore, but I went to see it for the 3-D process. It had been ballyhooed in the press so that even service personnel overseas had heard of it, though it never screened at the Post theater.<br /><br />The film started the trend of throwing objects at the audience, which was taken to absurd levels with later 3-D films.<br /><br />I don't know whether this qualifies as a spoiler, but you've been warned if it is. In many films of the time, actors would often work in front of a "rear projection screen," where backgrounds could be projected to make it appear that they were in a different environment, such as a jungle background when the actors were actually on a sound stage. This works well on regular films, but when seen in 3-D, they look like a flat scene behind the actors. There were several scenes in the film where rear projection was used, and it didn't work well in the theaters. If seen in 3-D, it will constitute another disappointment.<br /><br />The film's only importance is historical, since it was the first of its kind.
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The Treasure of Gazteluberri is a set of coins, of different materials gold, silver and iron, buried at the end of the 16th century CE or the beginning of the 17th. It contains pieces of Joanna I, Philip II and Charles I stored within a cowbell coming from the mint of Seville. Currently it can be found at the Museo Arqueológico Nacional, in Madrid with the inventory number 233. Discovery Its discovery took place in 1960 by Juan Berasategui y Urquía and Eugenio Martín Zazo in the municipality of Segura, Guipúzcoa. The environment and location of the finding may indicate the Treasure was buried in a moment of instability with the purpose of keeping it safe, therefore its property may have been linked some rancher or smuggler. References Collection of the National Archaeological Museum, Madrid Treasure troves in Spain
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“…heart-stopping brilliance… It sears you in a way it never could on the stereo.” The Guardian UK. Nomadic sibling duo, CocoRosie, will be making their third trip to Australia this January. American born sisters Bianca “Coco” and Sierra “Rosie” Casady began creating their unique blend of pop, folk, blues, electronica, gospel, opera and hip hop while living in Paris in 2003. After becoming estranged for almost a decade, upon reuniting they discovered an instant artistic connection and their first album La Maison de Mon Rêve was released is 2004. A continuous cycle of recording and touring followed, with the acclaimed Noah’s Ark released in 2005, and The Adventures of Ghosthorse and Stillborn in 2007. The duo spent much of 2008 and 2009 preparing their fourth album Grey Oceans while touring through Buenos Aires, Melbourne, Berlin, New York, and Paris. While in Melbourne, CocoRosie filmed a yet to be released movie in collaboration with Australian director Emma Freeman. At the same time, Emma also produced the duo’s haunting music video for their single ‘Lemonade’ and ‘Gallows’, filmed in the Victorian rural town of Yandoit. Sierra’s operatic and Bianca’s child-like vocals, combined with their fairytale lyrics, draws the listener into a magical alternate reality. Their sound is often created worldly and unconventional instruments, such as children’s toys, the Chinese harp, Hawaiian violin, Mexican guitars, synths, vintage pianos and various exotic noisemakers. Prepare to enter CocoRosie’s intricately spun, thoroughly imagined world when they perform at the Sydney Opera House, then head to Melbourne to play the Prince Bandroom. “…something entirely beautiful.” NME. Full of contradictions, the album is primitive and ultra-modern, dark and enchanting, tranquil and energetic.” Billboard magazine.
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How to Start a Foal's Training When raising a foal, there are certain helpful ways to go about it. The most practical way that ensures the safety of the foal around farriers and vets, or people in general, is starting with tack. This allows a foal to learn to be contained and led by the halter, which can be very helpful in the event that a risky situations come up. 1. Image titled Start a Foal's Training Step 1 Motivate the foal's natural instincts. Instilling a horse's natural behaviour is an important concept of training. These behaviours include following what is leaving them and going away from what is coming toward them. The idea is to incorporate this while keeping the foal comfortable and not alarmed. A foal will act upon its herding instincts the more it feels connected to you, which makes it easier to train and ride afterwards. 2. Image titled Start a Foal's Training Step 2 Make use of the mother's involvement for halter training. Depending on how strong your foal is will determine when you can start halter training. Having the foal's mother know that you have the foal's best interest in mind is your first step. Having a happy mom is asking for a happy foal. Foals follow their mother. This is something all trainers can use to their advantage: • By leading the mother from one side of the field to the other a few times, the foal understands the pattern. • You can then put the halter on the foal. However, you will want to teach your foal to hold still. This will teach it not to struggle in frightening situations. Putting your one hand on the foal's chest and the other around the foal's backside, hold the foal in your arms. This is the time to use the reward system. After the foal stops struggling, let it go. Repeat this until the foal understands the routine. 3. Image titled Start a Foal's Training Step 3 Use a butt rope to keep the best control over the foal when needed. Having put the halter on after teaching the foal to be contained, you are ready to lead it. At this point, go along with any outbursts while walking along by the foal's mother. This will help the foal to settle down knowing that you aren't trying to make it leave its mothers side. You can use the butt rope to turn the foal back to you if it tries to get out of your grasp. With practice and repetition, by the time a week is up, the foal will understand the routine and should be able to lead with just a lead rope. 4. Image titled Start a Foal's Training Step 4 Advance the training. Depending on how well the foal's training is progressing, you can start at about three months old to start teaching it to stand and turn towards and away from you. You can teach a foal to stand for longer periods of time by taking the time to scratch it if it wants to be scratched. Taking advantage of small things like this is to your benefit as a trainer. Your foal should be able to lead with a lead rope at this stage. 5. Image titled Start a Foal's Training Step 5 Teach the routine of leading and stopping next. Lead the foal around and stop at different intervals. At these stops, you can get your foal to practice standing and/or turning towards or away from you. As your foal learns how to stand still, it will also be learning how to pick up its feet. However, the picking up of the feet can be started sooner than at three months of age. 6. Image titled Start a Foal's Training Step 6 Do not handle your foal too much, otherwise your foal can turn into a brat. After you have taught your foal the basics of standing, leading, picking up its feet, etc., you can leave the foal alone. Until it is about two years old, give your foal a break in training so as to not have a horse that can outwit you. No extra training is needed. Of course, the practice of already learned skills is necessary but only enough to ensure that your foal remembers for the next time it has to learn something new. 7. Image titled Start a Foal's Training Step 7 Undertake all foal training gradually. Your best chance in your approach to training your foal is to progress in baby steps and to determine the level of training your foal can exceed at and then you're good to go. Article Info Categories: Horse Training
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Baby Physics Baby Physics This is what I call Baby Physics. They’re ‘real world’ items. They can crawl in and out. Toys can disappear only to reappear again. The sides and corners are planes and angles. Just like playing with a wooden spoon and a plastic mixing bowl. They’re what you use everyday and what’s teaching real world physics. That expensive toy with all the lights and buttons and music is just that. It doesn’t flip over and turn into something else. It’s just lights buttons and music. Another Baby Physics Lesson is ‘The Dropsy Game’. The 'game' where babies and little kids drop things from their highchairs.  They're learning about gravity. Yes, it can be totally annoying if you’re trying to get other things done, but just breathe and enjoy the moment. Eventually, you can draw the game to a close and move on to clean up. As they get older you’ll teach them how to behave at the table, but gravity is definitely something to learn about. In our house, ‘gravity storms’ happen when towers of blocks fall over or when someone stumbles. (This of course works with older kids who get the joke and it can lighten the mood.) Babies don’t understand physics until you teach them. They don’t understand that they can fall down the stairs, which is why it is recommended to have gates at the tops and bottoms of stairwells.  You’ve heard that babies are like sponges. They’re learning one or more languages. Their bodies are developing their gross and fine motor skills. They’re learning to love and trust. They’re also learning about the laws of physics. They won’t be able to name them, that’ll come later, but they’ll understand how the world functions through Baby Physics. So true! I have 19 month old twins and they LOVE empty diaper boxes! Fascinates them for what seems like hours. They also love tupperware, the laundry basket & the hamper 10/21/2011 10:11:28 PM Leave comment  Security code
dclm_baseline
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TIME22:43ONLINE3 TIME22:44ONLINE3 TIME22:44ONLINE3 TIME22:45ONLINE3 TIME22:46ONLINE4 TIME22:46ONLINE4 TIME22:47ONLINE4 TIME22:47ONLINE4 TIME22:48ONLINE4 TIME22:48ONLINE4 TIME22:49ONLINE4 TIME22:49ONLINE4 TIME22:49ONLINE5 TIME22:50ONLINE5 TIME22:51ONLINE5 TIME22:51ONLINE5 TIME22:51ONLINE6 TIME22:52ONLINE6 TIME22:52ONLINE7 TIME22:53ONLINE7 TIME22:54ONLINE7 1633877652676:336471583:妖老板在画画 1633877658880:2900187:恩呢 TIME22:54ONLINE7 TIME22:55ONLINE7 TIME22:55ONLINE7 TIME22:55ONLINE8 TIME22:56ONLINE8 TIME22:57ONLINE8 TIME22:57ONLINE8 TIME22:57ONLINE7 TIME22:58ONLINE7 TIME22:58ONLINE8 TIME22:59ONLINE8 TIME23:0ONLINE8 TIME23:0ONLINE8 TIME23:1ONLINE8 TIME23:1ONLINE8 TIME23:2ONLINE7 TIME23:2ONLINE7 TIME23:3ONLINE7 TIME23:3ONLINE7 TIME23:4ONLINE7 TIME23:4ONLINE7 TIME23:4ONLINE8 TIME23:5ONLINE8 TIME23:5ONLINE8 TIME23:6ONLINE8 TIME23:7ONLINE8 TIME23:7ONLINE8 TIME23:8ONLINE8 TIME23:8ONLINE8 TIME23:9ONLINE8 TIME23:9ONLINE9 TIME23:10ONLINE9 TIME23:10ONLINE9 TIME23:10ONLINE8 TIME23:11ONLINE8 TIME23:12ONLINE8 TIME23:12ONLINE8 TIME23:13ONLINE8 TIME23:13ONLINE8 TIME23:14ONLINE8 TIME23:14ONLINE8 TIME23:15ONLINE8 TIME23:15ONLINE8 TIME23:16ONLINE8 TIME23:16ONLINE8 TIME23:17ONLINE8 TIME23:17ONLINE8 TIME23:17ONLINE7 TIME23:18ONLINE7 TIME23:19ONLINE7 TIME23:19ONLINE7 TIME23:20ONLINE7 TIME23:20ONLINE6 TIME23:21ONLINE6 TIME23:21ONLINE6 TIME23:22ONLINE6 TIME23:22ONLINE6 TIME23:23ONLINE6 TIME23:23ONLINE7 TIME23:24ONLINE7 TIME23:24ONLINE7 TIME23:25ONLINE7 TIME23:25ONLINE6 TIME23:26ONLINE6 TIME23:26ONLINE6 TIME23:27ONLINE6 TIME23:27ONLINE6 TIME23:28ONLINE6 TIME23:28ONLINE6 TIME23:29ONLINE6 TIME23:29ONLINE5 TIME23:30ONLINE5 TIME23:30ONLINE6 TIME23:31ONLINE6 TIME23:31ONLINE5 TIME23:32ONLINE5 TIME23:32ONLINE6 TIME23:33ONLINE6 TIME23:33ONLINE6 TIME23:34ONLINE6 TIME23:34ONLINE6 TIME23:35ONLINE6 TIME23:35ONLINE6 TIME23:36ONLINE6 TIME23:36ONLINE6 TIME23:37ONLINE6 TIME23:37ONLINE6 TIME23:38ONLINE6 TIME23:39ONLINE6 TIME23:39ONLINE7 TIME23:40ONLINE7 TIME23:40ONLINE7 TIME23:41ONLINE7 TIME23:41ONLINE8 TIME23:41ONLINE7 TIME23:42ONLINE8 TIME23:42ONLINE8 TIME23:43ONLINE8 TIME23:43ONLINE8 TIME23:44ONLINE8 TIME23:44ONLINE8 TIME23:45ONLINE8 TIME23:45ONLINE7 TIME23:46ONLINE7 TIME23:46ONLINE7 TIME23:47ONLINE7 TIME23:47ONLINE7 TIME23:48ONLINE7 TIME23:48ONLINE7 TIME23:49ONLINE7 TIME23:49ONLINE7 TIME23:50ONLINE7 TIME23:50ONLINE7 TIME23:51ONLINE7 TIME23:51ONLINE8 TIME23:52ONLINE8 TIME23:52ONLINE8 TIME23:53ONLINE8 TIME23:53ONLINE8 TIME23:54ONLINE8 TIME23:54ONLINE8 TIME23:55ONLINE8 TIME23:55ONLINE8 TIME23:56ONLINE8 TIME23:56ONLINE8 TIME23:57ONLINE8 TIME23:57ONLINE8 TIME23:58ONLINE8 TIME23:58ONLINE9 TIME23:59ONLINE9 TIME23:59ONLINE8 SPEAKERNUM2;2900187:妖慕心_channel:1,336471583:星之羽琉璃:1 V2
the_stack
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look up any word, like blumpkin: The romantic relationship between Bam Margera and Ryan Dunn. Dude!! I found fanfictions of Bam Margera and Ryan Dunn having sex! by Abaddon May 02, 2005 Abbreviation for the slash pairing of Ryan Dunn and Bam Margera. If they got any publicly gayer, slash writers wouldn't even have to use their imaginations. The bam_ryan_otp community on livejournal is basically the center of the Dugera universe. Bam and Ryan (Dugera) "joke" about screwing each other all the time. They've done a lot of REALLY gay publicity stunts, and just looking at pictures of them you can tell. by high_school_low December 01, 2006
dclm_baseline
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Q: Linked list for text editor in c++ Im trying to write a text editor in c++. And each line of text has to go into a node of a linked list. Ive got must of the linked list finished, all I need now is how to put each line of text into each node. Thats my question, how to put each line of text into each node. Here's my code: typedef int ListItemType; typedef Strac Node* NodePtr; Struc Node { ListItemType data; NodePtr next; }; int main() { //Create empty list NodePtr head = NULL; //1st node head = new Node; //Initialize the field head -> data = ?; head -> next = NULL; //2nd node head -> next = new Node; //Initialize the field head -> next -> data = ?; head -> next -> next = NULL; } Im guessing that each line of text goes where the question marks are at? Thanks A: Text Editors generally back their editing buffer with a Rope data structure Furthermore, there is a standard doubly linked list data structure in C++ called std::list. If you want to represent a single line of text perhaps you should use a std::string: typedef std::string ListItemType;
mini_pile
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2.9.8. Creating regular annotations When there is a time interval you wish to divide in a number of adjacent annotations with the same duration you can do that by clicking on Tier > Create Regular annotations. In the dialog window (see Figure 2.81) select the tiers that must receive the new annotations. Then do one of the following: 1. Enter Start time and Duration (End time is calculated automatically). 2. Enter Start time and End time (Duration is calculated automatically). Finally, enter a Annotation size and click Apply. Regular Annotations Figure 2.81. Regular Annotations The total duration of the new annotations does not exceed the interval between start and end time. So if start time is 1.000 seconds and, end time is 4.000 seconds (interval of 3 seconds) and the annotation size is 2.000 seconds, than only one new annotations is created because two would make a duration of 4 seconds which exceeds the interval defined by the start and end time. If there is an overlap between the new annotations and one or more existing annotations, these existing annotations will be removed.
dclm_baseline
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Sample Resume for Cafe assistant: 34 Belief Free Download Last modified date An management assistant cover letter sample will lead you on how to produce your letter project you in a great light. It will tell you how to use them to your advantages. It will teach you how you can show your personality and remain professional concurrently. Your cover letter should be engaging. Rather than making it generic, it is advisable to include a specific individual tackled. The cover letter produces a very first impression of you in the front of the recruiter. The most beneficial part is it just isn’t tough to compose a great assistant cover letter. The perfect cover letter for administrative assistant is one which is short yet compelling. Writing an outstanding medical assistant job application letter is not so hard if you understand how. Sample Resume For Cafe Assistant F839cea45d828d8c8362b5fd46fd730767 Inspiring Sample Resume For Restaurant – Sample Resume The cover letter is a chance to expand for the information that you have currently provided. It is considerably better send a nicely written letter to help you to receive work interview. A perfect medical assistant cover letter is professional, brief and highlights everything you could bring about a small business or organization. The positioning you’re trying to find may be the medical office assistant. You can choose the very best one which suits the positioning you’ve applied for. When you are entering an management position for the first time, then your key skills should consist of relevant transferable skills like attention to detail, company abilities and capacity to work accurately pressurized. You probably need a location that will offer you many opportunities for making it, let you earn a pile of cash and allow you to reach wonderful heights in the career. So call and make an outstanding impression the very first time if you truly want the position you’re applying for. Status the work position you wished to apply for. Status why you could be enthusiastic about the job. Given an administrative assistant’s job is quite vital, buying the position isn’t simple. So rather than publishing just one resume, it is actually preferable to tailor every single one for a particular assistant medical job. If you are now applying for work or searching for a fresh role at some point you will definitely be asked to publish a cover letter like a portion of the application. Work in health care will require that you have a specific background, but they’ll also need you to be a certain type of person. Now, as soon as a job comes along, simply tweak a few locations and you own a custom resume. Because you are asking for a medical job which might contain administrative duties like answering correspondence, they have essential to compose an extremely professional medical assistant cover letter. You will receive the ideal jobs if you do your very best self. The fundamental job of an nursing student is always to help the wellness specialists in various therapy methods. An effective people manager doesn’t need to get preferred, but they do need to demonstrate respect and also to obtain respect. Your wellbeing care assistant resume is the very first thing any employer will appear for closely. Since the skilled office assistants are expected to execute paperwork duties, you must have the capability to continue to keep your work cool. Gallery of sample resume for cafe assistant [gembloong_gallery limit=100 random=false] Vickie J. Skeen
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Q: select top 5 in entity framework I have [Person] PersonID, EmailAddress, FirstName, LastName [OnlineAccount] OnlineAccountID, PersonID, Nickname Each person is allowed to have 0-* OnlineAccount. In entity framework with C#, how do I select the top 5 Person that has the most accounts? A: Try this: var items = context.PersonSet.OrderByDescending(u => u.OnlineAccounts.Count).Take(5); This returns IQueryable<Person>. It doesn't return results yet, because it implements deferred execution. It will be translated to SQL and executed when needed: var metarializedItems = items.ToList(); // ToList forces execution or foreach(var item in items) // foreach forces execution Example above will translate to SQL similar to this one: SELECT TOP 5 p.PersonID, p.EmailAddress, p.FirstName, p.LastName FROM Person p ORDER BY (SELECT COUNT(*) FROM OnlineAccount oa WHERE p.PersonID = oa.PersonID) DESC It won't be this exact SQL. Different EF version may produce different SQLs, but I wrote it to ilustrate how it works. Take(5) is translated to TOP 5. OrderByDescending(u => u.OnlineAccounts.Count) is translated to ORDER BY (SELECT COUNT(*) FROM OnlineAccount oa WHERE p.PersonID = oa.PersonID) DESC. This is power of Entity Framework. It translates .NET expressions to SQL.
mini_pile
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Friday, April 9, 2010 Snackin' in Scranton: Eden, a vegan cafe I love vegan food and baked goods. But let's be clear about one thing: I'm NOT vegan. I hope I didn't break any of your hearts. I was vegetarian for about 10 years, and vegan for 2 of them. And of course, there's that whole lactose-intolerant thing. But every once in a while you'll catch me eating potato pizza or fish tacos or using butter in my pie crust. (My vegan crust is pretty tasty, but you just can't beat butter sometimes! sigh...)  In Philly it's pretty easy to eat vegetarian. Most of the bar/restaurants I frequent have awesome menu standards and specials that are cruelty-free and delicious. But a place that's 100% without a doubt, no ifs-ands-or-buts about it VEGAN? None in Philly. You've got to go to Scranton for that.  Yeah, you heard me right. SCRANTON. It's quite lovely up there. And they've got yummy places to eat. Like Eden- a vegan cafe. If you follow along with this blog, you'll know I stayed home an extra night while visiting for Easter just to make sure I could grab lunch there. That's how delicious it is. And the service is super friendly, and the place is bright and airy and pretty and they're on the coolest block downtown (on Adams Ave, right across from the best bar in town and the awesome Thai place, but those are for another post...). And the owners are big PHILLIES fans. And if you live in the Scranton area or if you're like me and from Scranton but go home frequently to visit, then you need to go. Immediately. And thank me later.  Eden's got a full menu with soups, appetizers, salads, sandwiches (hot and cold), and desserts. They've also got weekly specials. I've yet to have anything from here that I didn't think was snack-tastic.  Before hitting the turnpike on Tuesday, I grabbed lunch with friends. This time around, I got one of the specials- the Waldorf Chicken Salad sandwich. Soy Protein "chicken" salad with Vegenaise, diced apples, sliced grapes, walnuts, romaine lettuce and tomatoes. It came on a multi-grain wrap, but I got mine on a hoagie roll. (Sometimes I just want some bread, and they're really accommodating at Eden.) The result was super delicious. The textures and flavors blended so well: the tart apple crunch, sweet squish of grapes and earthy chewiness of walnuts. The "chicken" was also spot on. I'm always really impressed with the faux meat products Eden uses. I usually get freaked out by the texture of seitan (which most restaurants use for their veg dishes), but I don't think they use it at Eden. With their sandwiches you get your choice of side. I usually order a super double secret side dish whose name I can't divulge, but I will show you pictures of it. As for the rest of you mortals, I'd recommend the slaw. I dream about their coleslaw some nights. OK, most nights. Alright, EVERY night. For REAL. Their smashed potatoes are most excellent too. (Surprise! The Irish girl loves potatoes too! Moving on...) I've never seen anyone order another side because both of those are so tasty, but I hear they have other options.  Carolyn got the unofficial "Michelle Williams" turkey club, which is a typical turkey club but with avocado slices. Why is it called the "Michelle Williams"? Because that's what Michelle ordered when she stopped into Eden before the Wilco show in Scranton. Yes, that Michelle Williams. Yes, that Wilco. Yes, in Scranton. Yes, I was confused too. Let's get back to the food.  The turkey club at Eden is the kind of thing that's so good I have a hard time ordering anything else. And I'm a firm believer that avocados can improve anything, so they managed to take this mighty sandwich to the next level of delicious. "Turkey" slices, vegan bacon strips, lettuce, tomato, Vegenaise, and avocado slices layered on whole wheat bread. But the avocado may have sent it over the edge, as it was pretty messy and Carolyn said she needed a bigger mouth to eat it (and she's got the biggest mouth of anyone I know).  This led Carolyn, the philosophy professor, to start talking about the turkey club paradox: "How could there be a sandwich too large for the largest mouth to fit? If you take a layer off is it still a turkey club? Does it's essence change in any way?"... and then Louie started arguing with Carolyn (like they always do) about her Aristotelian snack-theorizing, and I stopped listening and continued eating my hoagie. At the end of it all she said the turkey club was like a "sandwich explosion, but an explosion of deliciousness." Which are the best kind, obviously Louie had a Turkey Cobb Wrap (with avocado, bacon bits, ranch and lettuce) and Matt had the Waldorf wrap, both of which got two thumbs up. Dan joined us later and tried the Agave Nectar Mustard Salmon Wrap- grilled salmon strips, glazed with an agave nectar and Dijon mustard sauce, grilled pepper strips, and leafy greens on a multi-grain wrap. He was too busy snacking to get a comment, but it looked super yum! Of course, before we left I had to try some dessert (it's research, people!) and got the Banana Chocolate cheesecake. I'm not a fan of cheesecakes (real or vegan), but I know the girl that they buy the cheesecakes from and I promised her I'd give them a try. I'm so glad I did. The filling was nice and soft, with a mild banana flavor marbled with smooth chocolate on a thick bed of graham cracker crumbs. Kelly, please keep making these delicious cheesecakes. So I can keep putting them in my belly. I also took some slaw for the road, and had a super yummy post-drive snack in Philly.  I've only got one gripe about eden, and that's their hours. I wish they were open more! They close early most Saturdays and they're closed on Sundays and Mondays, which make it difficult for me to get there during my visits home. And leads me to stay in town longer than planned or beg friends to pick up orders. The slaw is that good! If I still lived in Scranton, I'd eat there everyday, and harass them into selling my treats. (Maura and Christian, I've gotta bring you guys some Casbah cupcakes or some Diddy cookies next time I'm home...) So go to Eden! What are you waiting for? That trip you've been meaning to take to Scranton to take the "Office" tour? Do it now! And stop in Eden for lunch and you might see the sexy crew above. Or if you work or live downtown or at the University of Scranton, order some takeout and a cute boy who looks suspiciously like Buddy Holly will deliver it to you on his bike (though don't get too excited girls, his lady-friend is way hotter than Mary Tyler Moore). But whatever you do, eat there soon! 344 Adams Ave Scranton PA 18503 (Become friends with them on facebook too!) 1. Colleen, fantastic blog! You are awesome. for special order cheesecakes email: 2. Eden is always my #1 choice for lunch when I'm in Scranton! 3. actually, there are totally vegan places in philly. Horizons is one of them 4. also, whats in the cup in the photo next to the to go bag? It looks awesome. Next time I'm home I'll try to swing by. The cheezecake looks great 5. Where is Horizons? I don't think I've ever heard of it. It's coleslaw in the cup. Their slaw is OUT OF THIS WORLD.
dclm_baseline
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From 4315b58e0bffedd145cec61f96062292cd98278e Mon Sep 17 00:00:00 2001 From: Pascal Bach <pascal.bach@nextrem.ch> Date: Thu, 23 Jul 2020 21:37:33 +0200 Subject: [PATCH] Make compatible with pdfminer.six version 20200720 --- setup.py | 2 +- src/ocrmypdf/pdfinfo/layout.py | 8 ++++++-- 2 files changed, 7 insertions(+), 3 deletions(-) diff --git a/setup.py b/setup.py index bd95ed9..d1f4ab1 100644 --- a/setup.py +++ b/setup.py @@ -83,7 +83,7 @@ setup( 'cffi >= 1.9.1', # must be a setup and install requirement 'coloredlogs >= 14.0', # strictly optional 'img2pdf >= 0.3.0, < 0.4', # pure Python, so track HEAD closely - 'pdfminer.six >= 20191110, <= 20200517', + 'pdfminer.six >= 20191110, <= 20200720', 'pikepdf >= 1.14.0, < 2', 'Pillow >= 7.0.0', 'pluggy >= 0.13.0', diff --git a/src/ocrmypdf/pdfinfo/layout.py b/src/ocrmypdf/pdfinfo/layout.py index 98bd82e..8b41e14 100644 --- a/src/ocrmypdf/pdfinfo/layout.py +++ b/src/ocrmypdf/pdfinfo/layout.py @@ -26,7 +26,11 @@ import pdfminer.pdfdevice import pdfminer.pdfinterp from pdfminer.converter import PDFLayoutAnalyzer from pdfminer.layout import LAParams, LTChar, LTPage, LTTextBox -from pdfminer.pdfdocument import PDFTextExtractionNotAllowed +try: + from pdfminer.pdfdocument import PDFTextExtractionNotAllowedError +except ImportError: + # Fallback for pdfminer < 20200720 + from pdfminer.pdfdocument import PDFTextExtractionNotAllowed as PDFTextExtractionNotAllowedError from pdfminer.pdffont import PDFSimpleFont, PDFUnicodeNotDefined from pdfminer.pdfpage import PDFPage from pdfminer.utils import bbox2str, matrix2str @@ -239,7 +243,7 @@ def get_page_analysis(infile, pageno, pscript5_mode): with Path(infile).open('rb') as f: page = PDFPage.get_pages(f, pagenos=[pageno], maxpages=0) interp.process_page(next(page)) - except PDFTextExtractionNotAllowed: + except PDFTextExtractionNotAllowedError: raise EncryptedPdfError() finally: if pscript5_mode: -- 2.27.0
mini_pile
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Dopuszczenie do obrotu 1 miesiąc + 10 dni po przyjęciu zgłoszenia, art. 146 ust. 3 rozporządzenia delegowanego (UE) 2015/2446 (1) dotyczący zgłoszenia uzupełniającego; „rozsądny termin” w odniesieniu do weryfikacji, art. 194 rozporządzenia (UE) nr 952/2013 Nie więcej niż: 60 dni 3. Procedury specjalne Termin zamknięcia procedury jest obowiązkowy w przypadku uszlachetniania czynnego, uszlachetniania biernego, końcowego przeznaczenia i odprawy czasowej (D. E. 4/17 w załączniku A do rozporządzenia delegowanego (UE) 2015/2446). Zamknięcie procedury celnej przez objęcie kolejną procedurą celną, wyprowadzenie poza obszar celny lub zniszczenie, art. 215 ust. 1 rozporządzenia (UE) nr 952/2013. a) Tranzyt unijny Nie więcej niż: 12 miesięcy po zwolnieniu do procedury b) Składowanie celne Nie więcej niż: 12 miesięcy po zakończeniu okresu przejściowego c) Wolne obszary celne Koniec okresu przejściowego d) Odprawa czasowa Nie więcej niż: 12 miesięcy po zwolnieniu do procedury e) Końcowe przeznaczenie Nie więcej niż: 12 miesięcy po zwolnieniu do procedury f) Uszlachetnianie czynne Nie więcej niż: 12 miesięcy po zwolnieniu do procedury g) Uszlachetnianie bierne Nie więcej niż: 12 miesięcy po zwolnieniu do procedury 4. Wywóz 150 dni po zwolnieniu do procedury 5. Powrotny wywóz 150 dni po zwolnieniu do procedury (1)  Rozporządzenie delegowane Komisji (UE) 2015/2446 z dnia 28 lipca 2015 r. uzupełniające rozporządzenie Parlamentu Europejskiego i Rady (UE) nr 952/2013 w odniesieniu do szczegółowych zasad dotyczących niektórych przepisów unijnego kodeksu celnego (Dz. U. L 343 z 29. 12. 2015, s. 1). ZAŁĄCZNIK IV WYKAZ SIECI, SYSTEMÓW INFORMATYCZNYCH I BAZ DANYCH, O KTÓRYCH MOWA W ART. 50, 53, 99 I 100 1. O ile Unia i Zjednoczone Królestwo nie uzgodnią inaczej, w celu zapewnienia państwom członkowskim i Zjednoczonemu Królestwu możliwości dalszej wymiany informacji w obecnym formacie zapewnia się zgodność wsteczną dla Zjednoczonego Królestwa i Unii w przypadku wszelkich zmian w sieciach, systemach informatycznych i bazach danych, a także zmian w formatach stosowanych przy wymianie informacji. 2. Zjednoczone Królestwo uzyskuje dostęp do danej sieci, danego systemu informatycznego lub danej bazy danych na określony czas. Taki okres określa się dla każdej sieci, każdego systemu informatycznego lub każdej bazy danych. W razie konieczności wymiany informacji między organami celnymi do celów wdrożenia procedur zgodnie z art. 49, gdy elektroniczne przetwarzanie danych nie jest już możliwe zgodnie z niniejszym załącznikiem, stosuje się alternatywne środki wymiany i przechowywania informacji. Część I: Cła System informatyczny organów celnych Rodzaj dostępu Data końcowa okresu dostępu ICS (system kontroli importu) Składanie deklaracji poprzedzającej przybycie ograniczone do: — otrzymywania i wysyłania danych przywozowej deklaracji skróconej (PDS) dotyczących deklaracji złożonych przed zakończeniem okresu przejściowego (w przypadku kolejnych portów lub zmiany kierunku); — otrzymywania i wysyłania danych na temat ryzyka w odniesieniu do tych deklaracji złożonych przed zakończeniem okresu przejściowego. 31 lipca 2021 r. NCTS (nowy skomputeryzowany system tranzytowy) Wszystkie funkcjonalności stosowane do trwających operacji tranzytowych, tj. przemieszczeń zwolnionych do tranzytu przed zakończeniem okresu przejściowego. [Brak możliwości zwalniania nowych operacji tranzytowych po zakończeniu okresu przejściowego. ] 31 stycznia 2021 r. ECS (system kontroli eksportu) Potwierdzenie wyprowadzenia dla trwających operacji wywozu, tj. towarów zwolnionych do wywozu przed zakończeniem okresu przejściowego: — w przypadku operacji z urzędami celnymi wyprowadzenia w Zjednoczonym Królestwie w celu potwierdzenia w ECS wyprowadzenia towarów; — w przypadku operacji z urzędami celnymi wyprowadzenia w państwach członkowskich, tj. urzędy celne wywozu w Zjednoczonym Królestwie mają otrzymywać potwierdzenia wyprowadzenia od urzędów celnych wyprowadzenia w państwach członkowskich. 31 stycznia 2021 r. INF (arkusz informacyjny) — Dostęp z prawem do odczytu dla przedsiębiorców ze Zjednoczonego Królestwa do specjalnego portalu dla przedsiębiorców w zakresie systemu INF; — dostęp z prawem do odczytu / zapisu do aktywnych arkuszy informacyjnych INF z prawem do odczytu i zapisu w systemie INF dla urzędów celnych. 31 grudnia 2021 r. SURV-RECAPP (system nadzorowania taryf – aplikacja odbiorcza) Przesyłanie elementów danych przez organy celne w Zjednoczonym Królestwie do celów dopuszczenia do obrotu lub procedur wywozu: — Zapisy zgłoszeń z nadzoru (Surveillance Declaration Records, SDR) nieprzesłane jeszcze do celów dopuszczenia do obrotu lub procedur wywozu, którymi towary zostały objęte przed zakończeniem okresu przejściowego; — elementy SDR do celów dopuszczenia do obrotu kończącego lub zamykającego trwającą procedurę lub sytuację. 28 lutego 2021 r. EBTI3 (europejski system wiążącej informacji taryfowej) Dane wejściowe na potrzeby obliczania długu celnego: Dostęp do informacji o decyzjach dotyczących wiążącej informacji taryfowej (WIT) lub wszelkich kolejnych zdarzeń, które mogą wpływać na pierwotny wniosek lub decyzję [pełen dostęp w celach konsultacji]. 8 stycznia 2021 r. TARIC3 (zintegrowana taryfa celna wspólnoty) Dane wejściowe na potrzeby obliczania długu celnego: Przesyłanie codziennie aktualizowanych informacji do Zjednoczonego Królestwa po zakończeniu okresu przejściowego, z wyjątkiem danych poufnych (danych dotyczących nadzoru statystycznego). 31 grudnia 2021 r. QUOTA2 (system zarządzania kontyngentami taryfowymi, plafonami i nadzorami) Dane wejściowe na potrzeby obliczania długu celnego: Zarządzanie kontyngentami, anulowanie zapytań o kontyngenty i zwrot niewykorzystanych ilości przyznanych w ramach kontyngentów taryfowych. 6 stycznia 2021 r. SMS TRA, EXP (system zarządzania wzorami) Dostęp z prawem do odczytu do bazy danych zawierającej wzory pieczęci, plomb i świadectw. 31 stycznia 2021 r. SMS QUOTA (system zarządzania wzorami) Dostęp z prawem do odczytu do bazy danych zawierającej świadectwa autentyczności niezbędne do korzystania z kontyngentów. 6 stycznia 2021 r. OWNRES (narzędzie informatyczne na potrzeby zasobów własnych służące do zgłaszania przypadków nadużyć i nieprawidłowości, w przypadku gdy dotyczą one tradycyjnych zasobów własnych przekraczających kwotę 10 000 EUR, art. 5 ust. 1 rozporządzenia (UE, Euratom) nr 608/2014) Ograniczony dostęp tylko do spraw dotyczących Zjednoczonego Królestwa (brak dostępu do analiz globalnych). 20 lutego 2026 r. WOMIS (system zarządzania odpisami i informacjami o odpisach do celów sprawozdań na temat spraw związanych z tradycyjnymi zasobami własnymi zgodnie z art. 13 ust. 3 rozporządzenia (UE, Euratom) nr 609/2014) Pełen dostęp, domyślnie już ograniczony do krajowych sprawozdań o przypadkach odpisania (dostęp z prawem do odczytu począwszy od dnia 1 lipca 2025 r. w ramach likwidacji odrębnego rachunku do dnia 31 grudnia 2025 r. ). 30 czerwca 2025 r. System wspierający Rodzaj dostępu Data końcowa okresu dostępu EOS/EORI (system przedsiębiorców – rejestracja i identyfikacja przedsiębiorcy) Dostęp z prawem do odczytu dla powiązanych systemów. 31 grudnia 2021 r. CDS (system decyzji celnych w ramach UKC) Dostęp z prawem do odczytu dla przedsiębiorców w Zjednoczonym Królestwie i dla urzędów celnych w Zjednoczonym Królestwie. 31 stycznia 2021 r. CS/RD2 (usługi centralne / dane referencyjne) Dostęp z prawem do odczytu dla danych referencyjnych; Dostęp z prawem do zapisu dla urzędów celnych NA-UK. 31 grudnia 2021 r. CS/MIS (usługi centralne / system informacji zarządczej) Dostęp z prawem do zapisu w celu załadowania niedostępności i statystyk gospodarczych. 31 lipca 2021 r. GTP (ogólny portal dla przedsiębiorców) Dostęp do ogólnych funkcji portalu dla przedsiębiorców w Zjednoczonym Królestwie do momentu wyłączenia ostatniego specjalnego portalu dla przedsiębiorców w Zjednoczonym Królestwie. 31 grudnia 2021 r. Sieć i infrastruktura Rodzaj dostępu Data końcowa okresu dostępu CCN (wspólna sieć łączności) Wiąże się z dostępem dla powiązanych systemów. 31 grudnia 2021 r. (lub dłużej, jeżeli jest to konieczne z uwagi na akcyzę lub opodatkowanie) UUM&DS (system jednolitego zarządzania użytkownikami i podpisu cyfrowego) Wiąże się z dostępem dla powiązanych systemów. 31 grudnia 2021 r. (lub dłużej, jeżeli jest to konieczne z uwagi na akcyzę lub opodatkowanie) CCN2 (wspólna sieć łączności 2) Wiąże się z dostępem dla powiązanych systemów. 31 grudnia 2021 r. (lub dłużej, jeżeli jest to konieczne z uwagi na akcyzę lub opodatkowanie) Część II: Akcyza System informatyczny dotyczący akcyzy Rodzaj dostępu Data końcowa okresu dostępu EMCS Core (system kontroli przemieszczania towarów akcyzowych) Zawieszenie poboru: Przesyłanie do i ze Zjednoczonego Królestwa raportów odbioru/wywozu (IE818). 31 maja 2021 r. EMCS Admin Coop (współpraca administracyjna dotycząca systemu kontroli przemieszczania towarów akcyzowych) — Przesyłanie do i ze Zjednoczonego Królestwa wiadomości dotyczących niezakończonych przemieszczeń (sprawozdania ze zdarzeń, sprawozdania z kontroli, współpraca administracyjna [zapytania dotyczące niezakończonych przemieszczeń w ramach systemu kontroli przemieszczania wyrobów akcyzowych]); 31 maja 2021 r. — państwa członkowskie i Zjednoczone Królestwo prowadzą współpracę administracyjną w ramach współpracy administracyjnej dotyczącej systemu kontroli przemieszczania towarów akcyzowych w trybie online, aby umożliwić zapytania i audyty dotyczące przemieszczeń do chwili zakończenia okresu przejściowego. 31 grudnia 2024 r. System wspierający Rodzaj dostępu Data końcowa okresu dostępu SEED (system wymiany informacji dotyczących podatku akcyzowego) Dostęp z prawem do odczytu, przy czym uprawnienia podmiotów gospodarczych ze Zjednoczonego Królestwa tracą ważność. 31 maja 2021 r. CS/MISE (usługi centralne / system informacji zarządczej do celów EMCS) Użycie filtru, aby ograniczyć do przemieszczeń dotyczących Zjednoczonego Królestwa. 31 maja 2021 r. Sieć i infrastruktura Rodzaj dostępu Data końcowa okresu dostępu CCN (wspólna sieć łączności) Wiąże się z dostępem dla powiązanych systemów. 31 maja 2021 r. (lub dłużej, jeżeli jest to konieczne z uwagi na akcyzę lub opodatkowanie) Część III: VAT System informatyczny dotyczący VAT Rodzaj dostępu Data końcowa okresu dostępu VAT-VIES (system wymiany informacji o VAT) Informacje o rejestracji podatników: Dostęp na zasadzie wzajemności do systemów informatycznych dla Zjednoczonego Królestwa i państw członkowskich (1) w celu wymiany, do dnia 31 grudnia 2024 r. , informacji drugiej strony o dokonanych rejestracjach (2) (dane o rejestracji podatników wprowadzone do systemu przed zakończeniem okresu przejściowego), a także informacji drugiej strony o rejestracji podatników zaktualizowanych po zakończeniu okresu przejściowego (np. zakończenie rejestracji podatnika). 31 grudnia 2024 r. (3) Transakcje – informacje o obrotach: Dostęp do systemów informatycznych dla Zjednoczonego Królestwa i państw członkowskich na zasadzie wzajemności w celu wymiany informacji zawartych w sprawozdaniach podsumowujących przedłożonych drugiej stronie w odniesieniu do transakcji, które miały miejsce (4) przed zakończeniem okresu przejściowego i w których uczestniczyli podatnicy strony otrzymującej; Zjednoczone Królestwo i państwa członkowskie nie mają dostępu do informacji drugiej strony o obrotach dotyczących transakcji mających miejsce po dniu 31 grudnia 2020 r. 31 grudnia 2024 r. Zwrot VAT Dostęp do systemu informatycznego w celu: — przekazywania państwom członkowskim wniosków o zwrot VAT składanych przez podatników mających siedzibę w Zjednoczonym Królestwie zgodnie z dyrektywą 2008/9/WE i rozpatrywania wniosków od państw członkowskich o zwrot VAT składanych przez podatników mających siedzibę w państwie członkowskim; 30 kwietnia 2021 r. — rozpatrywania (5) wniosków o zwrot VAT wpływających do Zjednoczonego Królestwa, składanych przez podatników mających siedzibę w państwie członkowskim oraz wniosków o zwrot VAT wpływających do państw członkowskich, składanych przez podatników mających siedzibę w Zjednoczonym Królestwie. 31 stycznia 2022 r. MOSS (mały punkt kompleksowej obsługi) Informacje o rejestracji: Dostęp do systemów informatycznych dla Zjednoczonego Królestwa i państw członkowskich na zasadzie wzajemności w celu:   — wymiany informacji na temat rejestracji i dokonanych rejestracji; 31 grudnia 2024 r. — rozpowszechniania informacji dotyczycących nowych rejestracji w MOSS, w przypadku rejestracji, których data rozpoczęcia obowiązywania przypada przed dniem lub w dniu 31 grudnia 2020 r. 20 lutego 2021 r. Deklaracja VAT: Dostęp do systemów informatycznych dla Zjednoczonego Królestwa i państw członkowskich na zasadzie wzajemności w celu:   — wymiany informacji na temat deklaracji złożonych za pośrednictwem systemu MOSS; dotyczy deklaracji złożonych przed dniem lub w dniu 31 stycznia 2021 r. ; 20 lutego 2021 r. — wymiany zmian w deklaracjach VAT złożonych za pośrednictwem systemu MOSS przed dniem lub w dniu 20 stycznia 2021 r. ; 20 stycznia 2022 r. — wymiany informacji o deklaracjach VAT dotyczących transakcji z udziałem drugiej strony; 31 grudnia 2024 r. — Zjednoczone Królestwo i państwa członkowskie nie mają dostępu do informacji drugiej strony na temat deklaracji VAT dotyczących transakcji mających miejsce po dniu 31 grudnia 2020 r. Informacje na temat płatności: Dostęp do systemów informatycznych dla Zjednoczonego Królestwa i państw członkowskich na zasadzie wzajemności w celu:   — wymiany informacji na temat płatności otrzymanych od przedsiębiorstw zarejestrowanych w systemie MOSS przed dniem lub w dniu 31 stycznia 2021 r. ; 20 lutego 2021 r. — w odniesieniu do transakcji podlegających opodatkowaniu u drugiej strony: wymiany informacji dotyczących zwrotów lub płatności z tytułu zmian w deklaracjach VAT za pośrednictwem systemu MOSS złożonych przed dniem lub w dniu 31 grudnia 2021 r. 20 stycznia 2022 r. System wspierający Rodzaj dostępu Data końcowa okresu dostępu CCN/eFCA Współpraca administracyjna w obszarze VAT (wspólna sieć łączności / centralny formularz zgłoszeniowy eForm) Przesyłanie wniosków między Zjednoczonym Królestwem i państwami członkowskimi – oraz działania następcze związane z takimi wnioskami – w odniesieniu do współpracy administracyjnej do celów VAT. 31 grudnia 2024 r. Preferencje dotyczące zwrotu VAT – Baza danych zawierająca informacje podatkowe (TIC) Dostęp Zjednoczonego Królestwa w celu aktualizacji preferencji Zjednoczonego Królestwa dotyczących zwrotu VAT. 31 marca 2021 r. Część IV: Pomoc przy odzyskiwaniu podatków i ceł System wspierający Rodzaj dostępu Data końcowa okresu dostępu CCN/eFCA Pomoc przy odzyskiwaniu Przesyłanie wniosków między Zjednoczonym Królestwem i państwami członkowskimi – oraz działania następcze związane z takimi wnioskami – w odniesieniu do pomocy przy odzyskiwaniu. 31 grudnia 2025 r. (1)  Na użytek niniejszego załącznika wyrażenie „dostęp na zasadzie wzajemności” oznacza, że Zjednoczone Królestwo musi zapewnić państwom członkowskim taki sam dostęp do takich danych w Zjednoczonym Królestwie, jaki Zjednoczone Królestwo i państwa członkowskie mają do takich danych w państwach członkowskich. (2)  Na użytek niniejszego załącznika wyrażenie „druga strona” oznacza państwo członkowskie w odniesieniu do Zjednoczonego Królestwa, a w odniesieniu do państwa członkowskiego – Zjednoczone Królestwo. (3)  Do dnia 31 grudnia 2024 r. należy zaktualizować dane Zjednoczonego Królestwa dotyczące numerów identyfikacyjnych VAT jego podatników. (4)  W tym transakcje, o których mowa w art. 51 ust. 1. (5)  Na użytek niniejszego tiret „rozpatrywanie” oznacza wykonanie wszystkich czynności dotyczących wniosku w celu umożliwienia jego sfinalizowania, w tym zgłoszenie wszelkich niedozwolonych kwot, wraz z podaniem szczegółowych informacji o sposobie odwołania, oraz spłatę wszelkich dozwolonych kwot, wraz z wymianą wszelkich istotnych wiadomości za pośrednictwem systemu zwrotu VAT. ZAŁĄCZNIK V EURATOM W niniejszym załączniku określa się kategorie sprzętu i pozostałego mienia należącego do Wspólnoty mającego związek z zapewnieniem zabezpieczeń na podstawie Traktatu Euratom, znajdującego się w Zjednoczonym Królestwie, które stają się własnością Zjednoczonego Królestwa w dniu zakończenia okresu przejściowego. W dniu zakończenia okresu przejściowego Komisja Europejska przekazuje Zjednoczonemu Królestwu ostateczny wykaz przekazanego sprzętu i pozostałego mienia Euratom. Zgodnie z art. 84 ust. 1 i art. 148 Zjednoczone Królestwo zwraca Unii kwotę odpowiadającą wartości tego sprzętu i pozostałego mienia, obliczoną na podstawie wartości przypisanej temu sprzętowi i pozostałemu mieniu w skonsolidowanym sprawozdaniu finansowym za 2020 r. Komisja Europejska powiadamia Zjednoczone Królestwo o tej wartości po jej ostatecznym zatwierdzeniu. Sprzęt Euratom znajduje się w następujących obiektach: — Sellafield (1) – zakładzie przetwarzania paliwa jądrowego w Zjednoczonym Królestwie; — Dounreay (2) – byłym ośrodku badań i rozwoju reaktorów prędkich w Zjednoczonym Królestwie; — Sizewell (3) – obiekcie z dwiema elektrowniami jądrowymi: Sizewell A (niedziałająca) i Sizewell B, w której nadal działa reaktor wodny ciśnieniowy; — Capenhurst (4) – zakładzie wzbogacania uranu: — Springfields (5) – zakładzie produkcji paliwa; — innych reaktorach oraz placówkach badawczych, medycznych i pozostałych obiektach, w których wykorzystywany jest sprzęt zabezpieczający. Sprzęt Euratom składa się z różnych elementów, które obejmują instalacje stałe i związane z nimi urządzenia niezbędne do obsługi tych instalacji stałych oraz tworzą integralną część całego zainstalowanego systemu: 1. Pieczęcie: — pieczęcie metalowe jednorazowego użytku; — pieczęcie z włókien światłowodowych do użytku jednorazowego i wielokrotnego; oraz — czytniki pieczęci. 2. Sprzęt do obserwacji: — cyfrowe i analogowe systemy obserwacji zabezpieczeń, składające się z jednego komponentu lub większej ich liczby. 3. Sprzętu do pomiaru (próba nieniszcząca): — różne rodzaje detektorów promieniowania gamma z przedwzmacniaczami oraz elektronicznymi urządzeniami obliczeniowymi do pomiaru promieniowania gamma; — różne rodzaje detektorów neutronów z przedwzmacniaczami oraz elektronicznymi urządzeniami obliczeniowymi do pomiaru neutronów; jak również — sprzęt do kaset paliwowych zawierających świeże i wypalone paliwo jądrowe, sprzęt do pomiaru zawartości beczek z uranem i koszulek zawierających pluton, w tym skanery prętów i kaset paliwowych, wagi i ogniwa obciążnikowe. 4. Sprzęt laboratoryjny (tworzący część laboratorium w zakładzie w Sellafield): — spektrometr mas (TIMS); — instrumenty pomiarowe oparte na promieniowaniu gamma i promieniowaniu X (np. densytometria wykorzystująca krawędź absorpcji K (ang. K-edge) i fluorescencja rentgenowska); oraz — komory rękawicowe ze sprzętem analitycznym, w tym densytometrem i wagami analitycznymi. Aby ułatwić najskuteczniejsze przekazanie tego sprzętu, Zjednoczone Królestwo i Wspólnota wprowadzą niezbędne rozwiązania prawne, aby zwolnić Wspólnotę z obowiązków i zobowiązań wynikających z zawartej przez nią umowy z dnia 25 marca 1994 r. z przedsiębiorstwem British Nuclear Fuels PLC (obecnie Sellafield Ltd). 5. Komputery i związany z nimi sprzęt (w biurach i systemach pomiaru): — komputery osobiste, jak również jak związany z nimi sprzęt, w tym infrastruktura do zdalnego przekazywania danych (zestawy baterii i źródła zasilania, urządzenia umożliwiające kontrolę większej liczby komputerów, sprzęt sieciowy, w tym światłowody, przewody i przetworniki ethernetowe, przełączniki, serwery portów szeregowych, router wirtualnej sieci prywatnej, kontroler czasu i domeny, szafy); jak również — związane z nimi serwery, monitory i drukarki. (1)  Sellafield Ltd, SELLAFIELD CA20 1PG, ZJEDNOCZONE KRÓLESTWO. (2)  Dounreay Site Restoration Ltd, KW14 7TZ THURSO CAITHNESS, ZJEDNOCZONE KRÓLESTWO. (3)  EDF Energy Nuclear Generation Limited – Sizewell B Power Station, SUFFOLK, IP16 4UR LEISTON. (4)  Urenco UK Limited, Capenhurst Works, CHESTER CH1 6ER, ZJEDNOCZONE KRÓLESTWO. (5)  Westinghouse Springfields Fuels Ltd, SALWICK PRESTON PR4 OXJ, ZJEDNOCZONE KRÓLESTWO. ZAŁĄCZNIK VI WYKAZ PROCEDUR WSPÓŁPRACY ADMINISTRACYJNEJ, O KTÓRYCH MOWA W ART. 98 1. Współpraca administracyjna między państwami członkowskimi w związku z deklaracjami dostawcy dotyczącymi pochodzenia towarów, sporządzanymi do celów handlu na warunkach preferencyjnych między Unią a niektórymi państwami (art. 61–66 rozporządzenia wykonawczego (UE) 2015/2447). 2. Współpraca administracyjna w zakresie weryfikacji świadectw pochodzenia wystawionych przez organy państw trzecich lub upoważnione przez nie agencje (specjalne niepreferencyjne ustalenia dotyczące przywozu) (art. 59 rozporządzenia wykonawczego (UE) 2015/2447) oraz weryfikacji dowodów pochodzenia wystawionych lub sporządzonych przez organy państw trzecich lub eksporterów z państw trzecich (uzgodnienia preferencyjne) (art. 108–111 i art. 125 rozporządzenia wykonawczego (UE) 2015/2447, art. 32 załącznika II do rozporządzenia Parlamentu Europejskiego i Rady (UE) 2016/1076, art. 55 załącznika VI do decyzji Rady 2013/755/UE oraz równoważne postanowienia umów preferencyjnych). 3. Wzajemna pomoc w kontekście odzyskiwania kwoty należności celnych przywozowych lub wywozowych odpowiadającej długowi celnemu (art. 101 ust. 1 i art. 102 ust. 1 rozporządzenia (UE) nr 952/2013, art. 165 rozporządzenia wykonawczego (UE) 2015/2447). 4. Wzajemna pomoc w kontekście przekazania kwoty należności celnych przywozowych lub wywozowych odpowiadającej długowi celnemu przez państwo członkowskie, które przyjęło zabezpieczenie, do państwa członkowskiego, w którym powstał dług celny (art. 92 ust. 1 lit. c) rozporządzenia (UE) nr 952/2013, art. 153 rozporządzenia wykonawczego (UE) 2015/2447). 5. Weryfikacja środków dowodowych potwierdzających unijny status celny (i pomoc administracyjna) (art. 153 rozporządzenia (UE) nr 952/2013, art. 212 rozporządzenia wykonawczego (UE) 2015/2447). 6. Wymiana informacji między organami dotycząca towarów powracających (art. 203 rozporządzenia (UE) nr 952/2013, art. 256 rozporządzenia wykonawczego (UE) 2015/2447). 7. Współpraca administracyjna w kontekście odzyskania innych opłat za towary objęte procedurą odprawy czasowej zgodnie z konwencją ATA lub konwencją stambulską (art. 226 ust. 3 lit. c) rozporządzenia (UE) nr 952/2013, art. 170 rozporządzenia wykonawczego (UE) 2015/2447). 8. Wzajemna pomoc służąca uzyskaniu dodatkowych informacji w celu podjęcia decyzji w sprawie wniosku o zwrot lub umorzenie (art. 22 i art. 116 ust. 1 rozporządzenia (UE) nr 952/2013, art. 175 rozporządzenia wykonawczego (UE) 2015/2447). 9. Weryfikacja i pomoc administracyjna w kontekście kontroli po zwolnieniu towarów, dotyczących informacji o operacjach tranzytu unijnego (art. 48 rozporządzenia (UE) nr 952/2013, art. 292 rozporządzenia wykonawczego (UE) 2015/2447). 10. Współpraca administracyjna w kontekście odzyskania innych opłat za towary objęte procedurami tranzytu (art. 226 ust. 3 lit. a), b) i c) rozporządzenia (UE) nr 952/2013, art. 167 i 169 rozporządzenia wykonawczego (UE) 2015/2447). 11. Powiadomienie o odzyskaniu należności celnych i innych opłat w ramach procedury tranzytu unijnego oraz tranzytu zgodnie z konwencją TIR (art. 226 ust. 3 lit. a) i b) rozporządzenia (UE) nr 952/2013, art. 168 rozporządzenia wykonawczego (UE) 2015/2447). 12. Bezpośrednia współpraca i wymiana informacji między państwami członkowskimi dotycząca kontroli wywozu produktów podwójnego zastosowania (art. 19 ust. 2 rozporządzenia Rady (WE) nr 428/2009). ZAŁĄCZNIK VII WYKAZ AKTÓW / PRZEPISÓW, O KTÓRYCH MOWA W ART. 128 UST. 6 1. Rozporządzenie Rady (WE) nr 2100/94 z dnia 27 lipca 1994 r. w sprawie wspólnotowego systemu ochrony odmian roślin (bez uszczerbku dla art. 96 ust. 1 niniejszej Umowy). (1) 2. Tytuły III i IX dyrektywy Parlamentu Europejskiego i Rady 2001/83/WE z dnia 6 listopada 2001 r. w sprawie wspólnotowego kodeksu odnoszącego się do produktów leczniczych stosowanych u ludzi, (2) rozporządzenie (WE) Parlamentu Europejskiego i Rady nr 1901/2006 z dnia 12 grudnia 2006 r. w sprawie produktów leczniczych stosowanych w pediatrii, (3) rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 1394/2007 z dnia 13 listopada 2007 r. w sprawie produktów leczniczych terapii zaawansowanej, (4) rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 141/2000 z dnia 16 grudnia 1999 r. w sprawie sierocych produktów leczniczych (5), tytuły III i VII dyrektywy Parlamentu Europejskiego i Rady 2001/82/WE z dnia 6 listopada 2001 r. w sprawie wspólnotowego kodeksu odnoszącego się do weterynaryjnych produktów leczniczych, (6) rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 470/2009 z dnia 6 maja 2009 r. ustanawiające wspólnotowe procedury określania maksymalnych limitów pozostałości substancji farmakologicznie czynnych w środkach spożywczych pochodzenia zwierzęcego, (7) rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 726/2004 z dnia 31 marca 2004 r. ustanawiające wspólnotowe procedury wydawania pozwoleń dla produktów leczniczych stosowanych u ludzi i do celów weterynaryjnych i nadzoru nad nimi oraz ustanawiające Europejską Agencję Leków, (8) rozporządzenie wykonawcze Komisji (UE) nr 520/2012 z dnia 19 czerwca 2012 r. w sprawie działań związanych z nadzorem nad bezpieczeństwem farmakoterapii, o których mowa w rozporządzeniu Parlamentu Europejskiego i Rady (WE) nr 726/2004 i w dyrektywie Parlamentu Europejskiego i Rady 2001/83/WE (9) oraz rozporządzenie Komisji (WE) nr 1234/2008 z dnia 24 listopada 2008 r. dotyczące badania zmian w warunkach pozwoleń na dopuszczenie do obrotu dla produktów leczniczych stosowanych u ludzi i weterynaryjnych produktów leczniczych. (10) 3. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 1907/2006 z dnia 18 grudnia 2006 r. w sprawie rejestracji, oceny, udzielania zezwoleń i stosowanych ograniczeń w zakresie chemikaliów (REACH), utworzenia Europejskiej Agencji Chemikaliów. (11) 4. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 1272/2008 z dnia 16 grudnia 2008 r. w sprawie klasyfikacji, oznakowania i pakowania substancji i mieszanin. (12) 5. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 1107/2009 z dnia 21 października 2009 r. dotyczące wprowadzania do obrotu środków ochrony roślin (13) oraz rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 396/2005 z dnia 23 lutego 2005 r. w sprawie najwyższych dopuszczalnych poziomów pozostałości pestycydów w żywności i paszy pochodzenia roślinnego i zwierzęcego oraz na ich powierzchni. (14) 6. Rozporządzenie Parlamentu Europejskiego i Rady (UE) nr 528/2012 z dnia 22 maja 2012 r. w sprawie udostępniania na rynku i stosowania produktów biobójczych. (15) 7. Rozporządzenie Parlamentu Europejskiego i Rady (UE) nr 536/2014 z dnia 16 kwietnia 2014 r. w sprawie badań klinicznych produktów leczniczych stosowanych u ludzi. (16) 8. Art. 16 rozporządzenia Komisji (WE) nr 1235/2008 z dnia 8 grudnia 2008 r. ustanawiającego szczegółowe zasady wykonania rozporządzenia Rady (WE) nr 834/2007 w odniesieniu do ustaleń dotyczących przywozu produktów ekologicznych z krajów trzecich. (17) 9. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 391/2009 z dnia 23 kwietnia 2009 r. w sprawie wspólnych reguł i norm dotyczących organizacji dokonujących inspekcji i przeglądów na statkach. (18) 10. Dyrektywa Parlamentu Europejskiego i Rady 2001/18/WE z dnia 12 marca 2001 r. w sprawie zamierzonego uwalniania do środowiska organizmów zmodyfikowanych genetycznie, (19) art. 6 ust. 3 lit. c) rozporządzenia Parlamentu Europejskiego i Rady (WE) nr 1829/2003 z dnia 22 września 2003 r. w sprawie genetycznie zmodyfikowanej żywności i paszy. (20) 11. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 1924/2006 z dnia 20 grudnia 2006 r. w sprawie oświadczeń żywieniowych i zdrowotnych dotyczących żywności. (21) 12. Rozporządzenie Parlamentu Europejskiego i Rady (UE) nr 1143/2014 z dnia 22 października 2014 r. w sprawie działań zapobiegawczych i zaradczych w odniesieniu do wprowadzania i rozprzestrzeniania inwazyjnych gatunków obcych. (22) 13. Rozporządzenie Parlamentu Europejskiego i Rady (WE) nr 767/2009 z dnia 13 lipca 2009 r. w sprawie wprowadzania na rynek i stosowania pasz. (23) (1)  Dz. U. L 227 z 1. 9. 1994, s. 1. (2)  Dz. U. L 311 z 28. 11. 2001, s. 67. (3)  Dz. U. L 378 z 27. 12. 2006, s. 1. (4)  Dz. U. L 324 z 10. 12. 2007, s. 121. (5)  Dz. U. L 18 z 22. 1. 2000, s. 1. (6)  Dz. U. L 311 z 28. 11. 2001, s. 1. (7)  Dz. U. L 152 z 16. 6. 2009, s. 11. (8)  Dz. U. L 136 z 30. 4. 2004, s. 1. (9)  Dz. U. L 159 z 20. 6. 2012, s. 5. (10)  Dz. U. L 334 z 12. 12. 2008, s. 7. (11)  Dz. U. L 396 z 30. 12. 2006, s. 1. (12)  Dz. U. L 353 z 31. 12. 2008, s. 1. (13)  Dz. U. L 309 z 24. 11. 2009, s. 1. (14)  Dz. U. L 70 z 16. 3. 2005, s. 1. (15)  Dz. U. L 167 z 27. 6. 2012, s. 1. (16)  Dz. U. L 158 z 27. 5. 2014, s. 1. (17)  Dz. U. L 334 z 12. 12. 2008, s. 25. (18)  Dz. U. L 131 z 28. 5. 2009, s. 11. (19)  Dz. U. L 106 z 17. 4. 2001, s. 1. (20)  Dz. U. L 268 z 18. 10. 2003, s. 1. (21)  Dz. U. L 404 z 30. 12. 2006, s. 9. (22)  Dz. U. L 317 z 4. 11. 2014, s. 35. (23)  Dz. U. L 229 z 1. 9. 2009, s. 1. ZAŁĄCZNIK VIII REGULAMIN WSPÓLNEGO KOMITETU I SPECJALNYCH KOMITETÓW Postanowienie 1 Przewodniczący 1. Wspólnemu Komitetowi współprzewodniczą członek Komisji Europejskiej i przedstawiciel rządu Zjednoczonego Królestwa na poziomie ministerialnym lub urzędnicy wysokiego szczebla wyznaczeni jako ich zastępcy. Unia Europejska i Zjednoczone Królestwo powiadamiają się wzajemnie na piśmie o wyznaczonych współprzewodniczących i ich zastępcach. 2. Współprzewodniczący przyjmują decyzje przewidziane w niniejszym regulaminie za obopólną zgodą. 3. Współprzewodniczącego, który nie może wziąć udziału w posiedzeniu, może zastąpić na tym posiedzeniu wyznaczony przedstawiciel. Współprzewodniczący lub jego wyznaczony przedstawiciel niezwłocznie informuje na piśmie drugiego współprzewodniczącego oraz sekretariat Wspólnego Komitetu o wyznaczeniu przedstawiciela. 4. Wyznaczony przedstawiciel współprzewodniczącego wykonuje jego uprawnienia w granicach określonych w wyznaczeniu. Wszelkie odniesienia w niniejszym regulaminie do współprzewodniczących rozumie się jako odniesienia obejmujące wyznaczonego przedstawiciela. Postanowienie 2 Sekretariat W skład sekretariatu Wspólnego Komitetu (zwanego dalej „sekretariatem”) wchodzą urzędnik Komisji Europejskiej i urzędnik rządu Zjednoczonego Królestwa. Sekretariat, działając z upoważnienia współprzewodniczących, wykonuje zadania powierzone mu na mocy niniejszego regulaminu. Postanowienie 3 Udział w posiedzeniach 1. Przed każdym posiedzeniem Unia i Zjednoczone Królestwo informują się wzajemnie za pośrednictwem sekretariatu o planowanym składzie delegacji. 2. W stosownych przypadkach i zgodnie z decyzją współprzewodniczących do udziału w posiedzeniach Wspólnego Komitetu mogą zostać zaproszeni eksperci lub inne osoby niebędące członkami delegacji w celu przekazania informacji na określony temat. Postanowienie 4 Posiedzenia 1. O ile współprzewodniczący nie postanowią inaczej, posiedzenia Wspólnego Komitetu odbywają się na przemian w Brukseli i Londynie. 2. W drodze odstępstwa od ust. 1 współprzewodniczący mogą postanowić, że posiedzenie Wspólnego Komitetu odbędzie się w formie wideokonferencji lub telekonferencji. 3. Każde posiedzenie Wspólnego Komitetu jest zwoływane przez sekretariat w terminie i miejscu uzgodnionym przez współprzewodniczących. Jeżeli Unia lub Zjednoczone Królestwo wniosły o odbycie posiedzenia, Wspólny Komitet dąży do odbycia go w terminie 30 dni od daty takiego wniosku. W nagłych przypadkach Wspólny Komitet podejmuje starania, by odbyć posiedzenie w krótszym terminie. Postanowienie 5 Dokumenty Dokumenty w formie pisemnej, na których opierają się obrady Wspólnego Komitetu, są numerowane i przekazywane Unii i Zjednoczonemu Królestwu przez sekretariat jako dokumenty Wspólnego Komitetu. Postanowienie 6 Korespondencja 1. Unia i Zjednoczone Królestwo przesyłają sekretariatowi swoją korespondencję skierowaną do Wspólnego Komitetu. Taka korespondencja może być wysyłana w dowolnej formie pisemnej, w tym przy użyciu poczty elektronicznej. 2. Sekretariat zapewnia, aby korespondencja kierowana do Wspólnego Komitetu była przekazywana współprzewodniczącym i rozsyłana, w stosownych przypadkach, zgodnie z postanowieniem 5. 3. Wszelką korespondencję, której nadawcą lub bezpośrednim odbiorcą są współprzewodniczący, przekazuje się do sekretariatu i rozsyła, w stosownych przypadkach, zgodnie z postanowieniem 5. Postanowienie 7 Porządek obrad 1. Sekretariat sporządza projekt wstępnego porządku obrad każdego posiedzenia. Projekt wstępnego porządku obrad, wraz z odpowiednimi dokumentami, przekazuje się współprzewodniczącym nie później niż na15 dni przed datą posiedzenia. 2. Wstępny porządek obrad zawiera punkty, o których włączenie do porządku obrad wystąpiła Unia lub Zjednoczone Królestwo. Wszelkie takie wnioski, wraz ze wszystkimi odpowiednimi dokumentami, składa się w sekretariacie nie później niż w na 21 dni przed rozpoczęciem posiedzenia. 3. Nie później niż na 10 dni przed datą posiedzenia współprzewodniczący decydują o wstępnym porządku obrad danego posiedzenia. Mogą zdecydować o opublikowaniu takiego wstępnego porządku obrad lub dowolnej jego części przed rozpoczęciem posiedzenia. 4. Wspólny Komitet przyjmuje porządek obrad na początku każdego posiedzenia. Na wniosek Unii lub Zjednoczonego Królestwa punkty inne niż te ujęte we wstępnym porządku obrad mogą zostać włączone do porządku obrad w drodze decyzji Wspólnego Komitetu. 5. W wyjątkowych przypadkach współprzewodniczący mogą zdecydować o odstąpieniu od terminów określonych w ust. 1 i 2. Postanowienie 8 Protokół obrad 1. O ile współprzewodniczący nie postanowią inaczej, projekt protokołu z każdego posiedzenia sporządza sekretariat, w terminie 21 dni od zakończenia posiedzenia. 2. Protokół obrad zasadniczo zawiera streszczenie każdego punktu ujętego w porządku obrad, a w stosownych przypadkach –informacje o: a) dokumentach przedłożonych przez Wspólny Komitet; b) wszelkich oświadczeniach, o których włączenie do protokołu obrad wniósł jeden ze współprzewodniczących; oraz c) przyjętych decyzjach, wydanych zaleceniach, uzgodnionych wspólnych oświadczeniach i przyjętych wnioskach operacyjnych dotyczących poszczególnych punktów. 3. W protokole obrad zawiera się wykaz imion i nazwisk, stanowisk i funkcji wszystkich osób uczestniczących w posiedzeniu. 4. Protokół obrad zatwierdzają na piśmie współprzewodniczący w terminie 28 dni od daty posiedzenia lub w innym terminie wskazanym przez współprzewodniczących. Członkowie sekretariatu podpisują uprzednio zatwierdzone dwie autentyczne wersje protokołu obrad. Unia i Zjednoczone Królestwo otrzymują po jednej z dwóch autentycznych wersji. Współprzewodniczący mogą zdecydować, że podpisanie i wymiana kopii w formie elektronicznej spełnia powyższy wymóg. 5. Sekretariat sporządza również streszczenie protokołu obrad. Współprzewodniczący, po zatwierdzeniu streszczenia, mogą zdecydować o jego opublikowaniu. Postanowienie 9 Decyzje i zalecenia 1. W okresach między posiedzeniami Wspólny Komitet może przyjmować decyzje lub zalecenia w drodze procedury pisemnej, jeżeli współprzewodniczący zdecydują o zastosowaniu takiej procedury. Procedura pisemna polega na wymianie not między współprzewodniczącymi. 2. Jeżeli Wspólny Komitet przyjmuje decyzje lub zalecenia, w tytule takich aktów podaje się odpowiednio słowo „decyzja” lub „zalecenie”. Sekretariat nadaje każdej decyzji lub zaleceniu numer seryjny oraz odnotowuje datę ich przyjęcia. 3. W decyzjach przyjętych przez Wspólny Komitet określa się dzień, w którym stają się one skuteczne. 4. Współprzewodniczący podpisują decyzje i zalecenia przyjęte przez Wspólny Komitet, a następnie sekretariat natychmiast przesyła je stronom. Postanowienie 10 Jawność i poufność 1. O ile współprzewodniczący nie postanowią inaczej, posiedzenia Wspólnego Komitetu są poufne. 2. Jeżeli Unia lub Zjednoczone Królestwo przekazują Wspólnemu Komitetowi lub dowolnemu specjalnemu komitetowi informacje uznawane za poufne lub chronione przed ujawnieniem na mocy ich przepisów ustawowych i wykonawczych, druga strona traktuje otrzymane informacje jako poufne. 3. Bez uszczerbku dla ust. 2 Unia i Zjednoczone Królestwo mogą indywidualnie zdecydować o opublikowaniu decyzji i zaleceń przyjętych przez Wspólny Komitet swoich odpowiednich dziennikach urzędowych. Postanowienie 11 Języki 1. Językami urzędowymi Wspólnego Komitetu są języki urzędowe Unii i Zjednoczonego Królestwa. 2. Językiem roboczym Wspólnego Komitetu jest język angielski. O ile współprzewodniczący nie postanowią inaczej, Wspólny Komitet prowadzi obrady na podstawie dokumentów sporządzonych w języku angielskim. Postanowienie 12 Koszty 1. Unia i Zjednoczone Królestwo pokrywają wszelkie koszty poniesione przez siebie w związku z udziałem w posiedzeniach Wspólnego Komitetu. 2. Wydatki związane z organizacją posiedzeń i sporządzeniem kopii dokumentów ponosi Unia w odniesieniu do posiedzeń odbywanych w Brukseli i Zjednoczone Królestwo w odniesieniu do posiedzeń odbywanych w Londynie. 3. Wydatki związane z tłumaczeniem ustnym na język roboczy i z języka roboczego Wspólnego Komitetu w czasie posiedzeń ponosi strona wnosząca o takie tłumaczenie ustne. Postanowienie 13 Specjalne komitety 1. O ile współprzewodniczący nie postanowią inaczej, bez uszczerbku dla ust. 2–3 niniejszego postanowienia, do specjalnych komitetów stosuje się odpowiednio postanowienia 1–12. 2. Specjalnym komitetom współprzewodniczą przedstawiciele wyznaczeni przez Komisję Europejską i rząd Zjednoczonego Królestwa. Unia Europejska i Zjednoczone Królestwo powiadamiają się wzajemnie o wyznaczonych przedstawicielach. 3. Wszystkie informacje i sprawozdania przedstawiane przez specjalny komitet zgodnie z art. 165 ust. 4 Umowy przekazuje się niezwłocznie Wspólnemu Komitetowi. Postanowienie 14 Sprawozdanie roczne Do dnia 1 maja następnego roku sekretariat sporządza dla każdego roku kalendarzowego sprawozdanie roczne z funkcjonowania Umowy przewidziane w art. 164 ust. 6 Umowy. Sprawozdanie roczne zatwierdzają i podpisują współprzewodniczący. ZAŁĄCZNIK IX REGULAMIN CZĘŚĆ A REGULAMIN ROZSTRZYGANIA SPORÓW I. Definicje 1. Na użytek niniejszego regulaminu stosuje się następujące definicje: a) „Strona” oznacza Unię albo Zjednoczone Królestwo; b) „skarżący” oznacza Stronę, która składa wniosek o powołanie organu arbitrażowego na podstawie art. 170 Umowy; c) „pozwany” oznacza Stronę, której zarzuca się, że dopuściła się naruszenia postanowienia niniejszej Umowy; d) „przedstawiciel Strony” oznacza pracownika lub inną osobę wyznaczoną przez Stronę, który to pracownik lub inna osoba reprezentuje Stronę w sporze rozstrzyganym na podstawie niniejszej Umowy; e) „doradca” oznacza osobę wyznaczoną przez Stronę w celu doradzania lub pomocy tej Stronie w związku z postępowaniem przed organem arbitrażowym; f) „asystent” oznacza osobę, która zgodnie z warunkami swojego powołania prowadzi badania lub pomaga członkowi organu arbitrażowego pod jego kierunkiem i kontrolą. II. Powiadomienia 2. W odniesieniu do powiadomień dokonywanych pomiędzy Stronami a organem arbitrażowym stosuje się następujące zasady: a) organ arbitrażowy przesyła wszelkie wnioski, zawiadomienia, oświadczenia pisemne i inne dokumenty jednocześnie obu Stronom; b) w przypadku gdy Strona przekazuje organowi arbitrażowemu wniosek, zawiadomienie, oświadczenie pisemne lub inny dokument, ma ona obowiązek przesłać w tym samym czasie jego kopię drugiej Stronie; oraz c) w przypadku gdy Strona przekazuje drugiej Stronie wniosek, zawiadomienie, oświadczenie pisemne lub inny dokument w związku ze sporem, ma ona obowiązek przesłać w tym samym czasie jego kopię organowi arbitrażowemu. 3. Wszelkich powiadomień, o których mowa w pkt 2, dokonuje się pocztą elektroniczną lub, w stosownych przypadkach, za pomocą dowolnych innych środków łączności, które zapewniają rejestrację wysłania powiadomienia. Powiadomienie uznaje się za doręczone w dniu jego wysłania, chyba że zostanie udowodnione, że było inaczej. Wszelkie powiadomienia przekazuje się, odpowiednio, do służby prawnej Komisji Europejskiej i do doradcy prawnego Ministerstwa Spraw Zagranicznych i Wspólnoty Narodów Zjednoczonego Królestwa. 4. Na pisemny wniosek Stron lub organu arbitrażowego Biuro Międzynarodowe Stałego Trybunału Arbitrażowego pełni rolę kanału komunikacji pomiędzy Stronami a organem arbitrażowym. 5. Niewielkie błędy pisarskie we wniosku, zawiadomieniu, oświadczeniu pisemnym lub innym dokumencie związanym z postępowaniem przed organem arbitrażowym można poprawić, dostarczając nowy dokument, w którym jasno zaznaczono zmiany. 6. Jeżeli ostatni dzień na dostarczenie dokumentu przypada w weekend lub w dniu ustawowo wolnym od pracy dla, stosownie do przypadku, Komisji Europejskiej lub Ministerstwa Spraw Zagranicznych i Wspólnoty Narodów Zjednoczonego Królestwa, dokument ten można dostarczyć następnego dnia roboczego. Najpóźniej w dniu 30 września każdego roku Unia i Zjednoczone Królestwo informują się nawzajem, a w sytuacji, o której mowa w pkt 4, także Biuro Międzynarodowe Stałego Trybunału Arbitrażowego, o dniach ustawowo wolnych od pracy dla, odpowiednio, służby prawnej Komisji Europejskiej oraz Ministerstwa Spraw Zagranicznych i Wspólnoty Narodów Zjednoczonego Królestwa. III. Wyznaczanie i zastępowanie członków organu arbitrażowego 7. Jeżeli zgodnie z art. 171 ust. 5 Umowy członka lub członków organu arbitrażowego wybiera się w drodze losowania, Biuro Międzynarodowe Stałego Trybunału Arbitrażowego powiadamia Strony niezwłocznie o dacie, godzinie i miejscu takiego wyboru. Strony mogą być obecne podczas wyboru. Procedurę wyboru przeprowadza się jednak niezależnie od nieobecności jednej ze Stron albo obu Stron. 8. Biuro Międzynarodowe Stałego Trybunału Arbitrażowego wystosowuje odpowiednie powiadomienie na piśmie do każdej osoby wybranej na członka organu arbitrażowego. W terminie 5 dni od daty tego powiadomienia każda wybrana osoba potwierdza swoją dostępność wobec Biura Międzynarodowego Stałego Trybunału Arbitrażowego i obu Stron. 9. Jeżeli jedna ze Stron uzna, że członek organu arbitrażowego nie spełnia wymogów kodeksu postępowania określonego w części B i w związku z tym powinien zostać zastąpiony, Strona ta powiadamia drugą Stronę w ciągu 15 dni od daty uzyskania dostatecznych dowodów świadczących o nieprzestrzeganiu kodeksu postępowania przez tego członka. 10. Strony konsultują się w ciągu 15 dni od powiadomienia, o którym mowa w pkt 9. Informują one członka organu arbitrażowego o zarzucie nieprzestrzegania kodeksu postępowania i mogą wezwać go do podjęcia kroków w celu naprawienia tej sytuacji. Strony mogą również podjąć wspólną decyzję o odwołaniu tego członka i wyborze nowego zgodnie z art. 171 Umowy. Jeżeli Strony nie dojdą do porozumienia w sprawie zastąpienia członka organu arbitrażowego innego niż przewodniczący, każda ze Stron może wystąpić z wnioskiem o przekazanie sprawy do rozstrzygnięcia przewodniczącemu organu arbitrażowego, którego decyzja jest ostateczna. Jeżeli przewodniczący organu arbitrażowego uzna, że członek organu arbitrażowego nie przestrzega kodeksu postępowania, przeprowadza się wybór nowego członka organu arbitrażowego zgodnie z art. 171 Umowy. 11. Jeżeli strony nie dojdą do porozumienia w sprawie zastąpienia przewodniczącego, każda ze Stron może wystąpić z wnioskiem o przekazanie sprawy do rozstrzygnięcia jednej z pozostałych osób, które zostały wspólnie zaproponowane przez Unię i Zjednoczone Królestwo do pełnienia funkcji przewodniczącego zgodnie z art. 171 ust. 1 zdanie trzecie Umowy (zwanej dalej „wybraną osobą”). Nazwisko wybranej osoby losuje Sekretarz Generalnego Stałego Trybunału Arbitrażowego. W przypadku gdy wybrana osoba uzna, że przewodniczący nie przestrzega kodeksu postępowania dokonywany jest wybór nowego przewodniczącego zgodnie z art. 171 Umowy spośród osób, które zostały wspólnie zaproponowane przez Unię i Zjednoczone Królestwo do pełnienia funkcji przewodniczącego, z wyłączeniem tej wybranej osoby. IV. Kwestie finansowe 12. Strony dzielą się równo wszystkimi kosztami związanymi z powołaniem i działaniem organu arbitrażowego, w tym wynagrodzeniami i zwrotami wydatków wypłacanymi członkom tego organu. 13. W terminie 7 dni od powołania organu arbitrażowego Strony uzgadniają z nim: a) wynagrodzenie wypłacane członkom organu arbitrażowego i zwroty ich wydatków; wysokość tych świadczeń powinna być racjonalna i zgodna ze standardami WTO; b) wynagrodzenia wypłacane asystentom; w przypadku każdego członka organu arbitrażowego – łączna kwota wynagrodzeń dla asystentów powinna być racjonalna i nie może w żadnym przypadku przekraczać jednej trzeciej wynagrodzenia danego członka. Uzgodnień tych można dokonać przy użyciu dowolnego środka łączności. V. Harmonogram i oświadczenia pisemne 14. W terminie 7 dni od daty jego powołania organ arbitrażowy określa – po zasięgnięciu opinii Stron – orientacyjny harmonogram postępowania. 15. Skarżący przekazuje swoje oświadczenie pisemne organowi arbitrażowemu nie później niż w ciągu 20 dni od dnia określenia orientacyjnego harmonogramu. Pozwany przekazuje swoje oświadczenie pisemne organowi arbitrażowemu nie później niż w ciągu 20 dni od dnia otrzymania kopii oświadczenia pisemnego skarżącego. VI. Działanie organu arbitrażowego 16. Wszystkie posiedzenia organu arbitrażowego prowadzi jego przewodniczący. Organ arbitrażowy może przekazać przewodniczącemu prawo podejmowania decyzji administracyjnych i proceduralnych. 17. O ile niniejsza Umowa lub niniejszy regulamin nie stanowią inaczej, organ arbitrażowy może prowadzić postępowania i obrady przy użyciu dowolnego środka łączności. 18. W obradach organu arbitrażowego mogą brać udział wyłącznie jego członkowie, lecz organ arbitrażowy może zezwolić, aby podczas obrad byli obecni asystenci członków. 19. Za sporządzenie orzeczenia lub decyzji odpowiadają wyłącznie członkowie organu arbitrażowego i zadania tego nie wolno delegować na inną osobę. 20. Biuro Międzynarodowe Stałego Trybunału Arbitrażowego zapewnia organowi arbitrażowemu obsługę sekretarską oraz pozostałe wsparcie logistyczne. 21. W przypadku pojawienia się kwestii proceduralnych, których nie obejmują postanowienia niniejszej Umowy ani niniejszego regulaminu, organ arbitrażowy może – po zasięgnięciu opinii Stron – podjąć decyzję w sprawie zastosowania odpowiedniej procedury, przy czym procedura ta musi być zgodna z niniejszą Umową i niniejszym regulaminem. 22. Jeżeli organ arbitrażowy uzna, że w ramach postępowania konieczna jest zmiana któregokolwiek z terminów określonych w niniejszym regulaminie lub dokonanie innych dostosowań proceduralnych lub administracyjnych, informuje Strony – na piśmie i po zasięgnięciu opinii Stron – o powodach takich zmian lub dostosowań, wskazując nowe terminy lub dostosowania, które są konieczne. VII. Rozprawy 23. W oparciu o orientacyjny harmonogram określony na podstawie pkt 14 przewodniczący – po zasięgnięciu opinii Stron i innych członków organu arbitrażowego – powiadamia Strony o dacie, godzinie i miejscu rozprawy. Informacje takie podaje się do wiadomości publicznej, chyba że rozprawa toczy się przy drzwiach zamkniętych. Organ arbitrażowym może postanowić – w porozumieniu ze Stronami – o odstąpieniu od przeprowadzenia rozprawy. 24. O ile Strony nie postanowią inaczej, rozprawa odbywa się w Hadze, w siedzibie Stałego Trybunału Arbitrażowego. 25. Organ arbitrażowy może zdecydować o przeprowadzeniu dodatkowych rozpraw, jeżeli Strony wyrażą na to zgodę. 26. Obecność wszystkich członków organu arbitrażowego podczas całej rozprawy jest obowiązkowa. 27. O ile Strony nie postanowią inaczej, na rozprawie mogą być obecne następujące osoby, niezależnie od tego, czy rozprawa ma charakter otwarty: a) przedstawiciele Strony; b) doradcy; c) asystenci; d) tłumacze ustni i pisemni oraz sprawozdawcy sądowi organu arbitrażowego; oraz e) biegli, zgodnie z decyzją organu arbitrażowego. 28. Każda ze Stron, nie później niż 5 dni przed datą rozprawy, przekazuje organowi arbitrażowemu i drugiej Stronie wykaz imion i nazwisk osób, które na rozprawie przedstawią w formie ustnej argumenty lub oświadczenia w imieniu danej Strony, oraz wykaz imion i nazwisk innych przedstawicieli oraz doradców, którzy będą obecni na rozprawie. 29. Organ arbitrażowy prowadzi rozprawę w następujący sposób, zapewniając, aby skarżącemu oraz pozwanemu przyznano równą ilość czasu zarówno na przedstawienie argumentów, jak i na odpowiedź na nie: a) argument: (i) argument skarżącego; (ii) argument pozwanego; b) odpowiedź: (i) odpowiedź skarżącego; (ii) replika pozwanego; 30. Organ arbitrażowy może kierować pytania do każdej ze Stron w dowolnym momencie rozprawy. 31. Organ arbitrażowy zapewnia przygotowanie transkrypcji rozprawy i jego dostarczenie Stronom możliwie jak najszybciej po rozprawie. Strony mogą zgłaszać uwagi dotyczące transkrypcji, a organ arbitrażowy może te uwagi uwzględnić. 32. W terminie 10 dni od daty rozprawy każda ze Stron może przekazać organowi arbitrażowemu dodatkowe oświadczenie pisemne dotyczące wszelkich kwestii, które pojawiły się w trakcie rozprawy. VIII. Pytania pisemne 33. Organ arbitrażowy może w każdym momencie postępowania zwracać się z pytaniami w formie pisemnej do jednej lub obu Stron. 34. Każda Strona ma możliwość przedstawienia pisemnych uwag dotyczących odpowiedzi drugiej Strony na pytania postawione przez organ arbitrażowy w terminie 5 dni od daty otrzymania kopii tych odpowiedzi. IX. Poufność 35. Wszystkie przekazane organowi arbitrażowemu informacje, które Strona zakwalifikowała jako poufne, są traktowane jako poufne przez drugą Stronę i przez organ arbitrażowy. Przekazując organowi arbitrażowemu oświadczenie pisemne zawierające informacje poufne Strona przekazuje również, w terminie 15 dni, oświadczenie pisemne niezawierające informacji poufnych, które podaje się do wiadomości publicznej. 36. Żadne z postanowień niniejszego regulaminu nie wyklucza możliwości publicznego ujawnienia przez Stronę jej własnych oświadczeń pisemnych, odpowiedzi na pytania postawione przez organ arbitrażowy lub transkrypcji argumentów przedstawionych w formie ustnej, pod warunkiem, że odnosząc się do informacji przedstawionych przez drugą Stronę, Strona nie ujawnia żadnych informacji, które druga Strona zakwalifikowała jako poufne. 37. Rozprawy przed organem arbitrażowym są jawne dla publiczności, chyba że oświadczenia i argumenty Strony zawierają informacje poufne albo obie Strony uzgodnią, że rozprawa ma się toczyć przy drzwiach zamkniętych. W takich przypadkach Strony zachowują poufność treści rozpraw przed organem arbitrażowym. X. Kontakty ex parte 38. Organ arbitrażowy nie spotyka się ani też nie komunikuje się ustnie w inny sposób ze Stroną pod nieobecność drugiej Strony. XI. Sprawy pilne 39. W sprawach pilnych, o których mowa w art. 173 ust. 2 Umowy, organ arbitrażowy – po zasięgnięciu opinii Stron – dostosowuje odpowiednio terminy, o których mowa w niniejszym regulaminie. Organ arbitrażowy powiadamia Strony o tych dostosowaniach. XII. Tłumaczenia pisemne i ustne 40. Językiem postępowania przed organem arbitrażowym jest język angielski. Decyzje organu arbitrażowego są wydawane w języku angielskim. 41. Każda Strona ponosi własne koszty tłumaczenia dokumentów przedstawianych organowi arbitrażowemu, które sporządzono pierwotnie w innym języku niż angielski, a także ewentualne koszty tłumaczenia ustnego podczas rozprawy na potrzeby jej przedstawicieli lub doradców. CZĘŚĆ B KODEKS POSTĘPOWANIA CZŁONKÓW ORGANÓW ARBITRAŻOWYCH Definicje 1. Na użytek niniejszego kodeksu postępowania stosuje się definicję „asystenta” zawartą w regulaminie. Ponadto „kandydat” oznacza osobę, której nazwisko znajduje się w wykazie, o którym mowa w art. 171 ust. 1 Umowy, i którą bierze się pod uwagę przy wyborze członków organu arbitrażowego na mocy tego artykułu. Obowiązki w ramach procesu 2. Każdy kandydat i członek organu arbitrażowego unika niewłaściwych zachowań lub ich znamion, jest osobą niezależną i bezstronną, unika bezpośrednich lub pośrednich konfliktów interesów i przestrzega wysokich standardów postępowania, aby zachować rzetelność i niezależność postępowania w sprawie rozstrzygnięcia sporu. Byli kandydaci lub członkowie organu arbitrażowego stosują się do obowiązków określonych w pkt 8, 9 i 10. Obowiązki w zakresie ujawniania informacji 3. Przed potwierdzeniem swojego wyboru na członka organu arbitrażowego na podstawie niniejszej Umowy kandydat ma obowiązek ujawnić Stronom na piśmie wszelkie znane mu interesy, związki lub kwestie, które mogą mieć wpływ na jego niezależność lub bezstronność, lub które mogą wywołać rozsądnie uzasadnione wrażenie niewłaściwego zachowania lub stronniczości w trakcie postępowania przed organem arbitrażowym. 4. Kandydaci i członkowie organu arbitrażowego informują o kwestiach dotyczących faktycznego lub potencjalnego naruszenia niniejszego kodeksu postępowania wyłącznie Wspólny Komitet; kwestie te są następnie rozważane przez Unię i Zjednoczone Królestwo. 5. Na każdym etapie postępowania przed organem arbitrażowym jego członkowie mają obowiązek ujawnić Stronom na piśmie wszelkie interesy, związki lub kwestie o charakterze opisanym w pkt 3, o których wiedzą lub właśnie się dowiedzieli. Należyta staranność członków organu arbitrażowego 6. Po wyborze, członkowie organu arbitrażowego w trakcie całego postępowania wykonują swoje obowiązki w sposób rzetelny i sprawny, przestrzegając przy tym zasad uczciwości i staranności. Członkowie organu arbitrażowego mają w szczególności obowiązek: a) brać pod uwagę jedynie kwestie poruszane w trakcie postępowania przed organem arbitrażowym oraz konieczne do wydania orzeczenia i nie mogą oni delegować tego obowiązku na inną osobę; b) podejmować wszystkie właściwe kroki w celu zapewnienia, aby ich asystenci znali pkt 2, 3, 4, 5, 9 i 10 oraz ich przestrzegali. Niezależność i bezstronność członków organu arbitrażowego 7. Członkowie organu arbitrażowego: a) są niezależni i bezstronni oraz unikają stwarzania wrażenia niestosownego zachowania lub stronniczości; członkowie nie kierują się własnymi interesami, naciskami z zewnątrz, względami politycznymi, żądaniami społecznymi, lojalnością wobec Unii albo Zjednoczonego Królestwa ani obawą przed krytyką; b) w sposób bezpośredni lub pośredni nie podejmują jakichkolwiek zobowiązań ani nie przyjmują korzyści mogących w jakikolwiek sposób zakłócić właściwe wykonywanie swoich obowiązków lub stworzyć wrażenie zakłócenia ich właściwego wykonywania; c) nie mogą wykorzystywać swojego stanowiska członka organu arbitrażowego do realizacji jakichkolwiek osobistych lub prywatnych interesów i unikają podejmowania działań, które mogą sprawiać wrażenie, że inne osoby mogą wywierać na nich wpływ ze względu na swoją szczególną sytuację; d) nie pozwalają na to, aby relacje lub zobowiązania finansowe, biznesowe, zawodowe, rodzinne lub społeczne miały wpływ na ich postępowanie lub osądy; e) unikają nawiązywania kontaktów lub uzyskiwania korzyści finansowych, które mogą mieć wpływ na ich bezstronność lub które mogą wywołać rozsądnie uzasadnione wrażenie niewłaściwego zachowania lub stronniczości; f) nie mogą omawiać z jedną Stroną lub obiema Stronami jakichkolwiek kwestii dotyczących przedmiotu lub przebiegu postępowania przed organem arbitrażowym pod nieobecność pozostałych członków organu arbitrażowego. Obowiązki byłych członków organu arbitrażowego 8. Wszyscy byli członkowie organu arbitrażowego unikają działań mogących stwarzać wrażenie, że wykonując swoje obowiązki, byli stronniczy lub odnosili korzyści z decyzji lub orzeczenia organu arbitrażowego. Poufność 9. CI2019144BG. 01000101. xml 25. 4. 2019    BG Официален вестник на Европейския съюз CI 144/1 СПОРАЗУМЕНИЕ за оттеглянето на Обединеното кралство Великобритания и Северна Ирландия от Европейския съюз и Европейската общност за атомна енергия (2019/C 144 I/01) ЕВРОПЕЙСКИЯТ СЪЮЗ И ЕВРОПЕЙСКАТА ОБЩНОСТ ЗА АТОМНА ЕНЕРГИЯ, И ОБЕДИНЕНОТО КРАЛСТВО ВЕЛИКОБРИТАНИЯ И СЕВЕРНА ИРЛАНДИЯ, КАТО ИМАТ ПРЕДВИД, че на 29 март 2017 г. Обединеното кралство Великобритания и Северна Ирландия („Обединеното кралство“), вследствие на резултатите от проведения в Обединеното кралство референдум и суверенното решение на страната да напусне Европейския съюз, уведоми за намерението си да се оттегли от Европейския съюз („Съюза“) и Европейската общност за атомна енергия („Евратом“) в съответствие с член 50 от Договора за Европейския съюз („ДЕС“), който се прилага по отношение на Евратом по силата на член 106а от Договора за създаване на Европейската общност за атомна енергия („Договора за Евратом“), КАТО ЖЕЛАЯТ да определят реда и условията за оттеглянето на Обединеното кралство от Съюза и Евратом, вземайки предвид рамката за техните бъдещи отношения, КАТО ОТБЕЛЯЗВАТ насоките от 29 април 2017 г. , 15 декември 2017 г. и 23 март 2018 г. , предоставени от Европейския съвет, с оглед на които Съюзът трябва да сключи споразумението, в което се определят редът и условията за оттеглянето на Обединеното кралство от Съюза и Евратом, КАТО ПРИПОМНЯТ, че съгласно член 50 от ДЕС във връзка с член 106а от Договора за Евратом и при спазване на реда и условията, определени в настоящото споразумение, правото на Съюза и на Евратом в своята цялост престава да се прилага спрямо Обединеното кралство от датата на влизане в сила на настоящото споразумение, КАТО ПОДЧЕРТАВАТ, че целта на настоящото споразумение е да се гарантира организирано оттегляне на Обединеното кралство от Съюза и Евратом, КАТО ПРИЗНАВАТ, че е необходимо да се осигури реципрочна защита на гражданите на Съюза и гражданите на Обединеното кралство, както и на съответните членове на техните семейства, когато те са упражнили правото си на свободно движение преди определената в настоящото споразумение дата, и да се гарантира, че правата им по настоящото споразумение могат да бъдат упражнени и се основават на принципа на недискриминация; като признават също, че правата, произтичащи от периодите на социално осигуряване, следва да бъдат защитени, РЕШЕНИ да осигурят организирано оттегляне посредством редица разпоредби за разделяне, с които се цели да се предотвратят смущения и да се осигури правна сигурност за гражданите и икономическите оператори, както и за съдебните и административните органи в Съюза и в Обединеното кралство, без да се изключва възможността съответните разпоредби за разделяне да бъдат заменени от споразумението (споразуменията) относно бъдещите отношения, КАТО ИМАТ ПРЕДВИД, че е в интерес както на Съюза, така и на Обединеното кралство да се определи преходен период или период на изпълнение, през който — независимо от всички последици от оттеглянето на Обединеното кралство от Съюза по отношение на участието на Обединеното кралство в институциите, органите, службите и агенциите на Съюза, и по-специално, считано от датата на влизане в сила на настоящото споразумение, края на мандатите на всички членове на институции, органи и агенции на Съюза, номинирани, назначени или избрани по силата на членството на Обединеното кралство в Съюза — правото на Съюза, включително международните споразумения, да се прилага за и във Обединеното кралство, и като общо правило, със същото действие както по отношение на държавите членки, за да се избегнат смущения в периода, през който споразумението(споразуменията) относно бъдещите отношения ще бъдe (бъдат) договорено(и), КАТО ПРИЗНАВАТ, че въпреки че правото на Съюза ще бъде приложимо за и във Обединеното кралство през преходния период, поради спецификата на Обединеното кралство като държава, която се е оттеглила от Съюза, за Обединеното кралство ще бъде важно да може да предприема стъпки за изготвянето и установяването на нови самостоятелни международни договорености, включително в области от изключителната компетентност на Съюза, при условие че такива споразумения не влизат в сила или не се прилагат през този период, освен ако това не е разрешено от Съюза, КАТО ПРИПОМНЯТ, че Съюзът и Обединеното кралство са се договорили да изпълнят взаимните ангажименти, поети по време на членството на Обединеното кралство в Съюза, чрез единно финансово споразумение, КАТО ИМАТ ПРЕДВИД, че за да се гарантира правилното тълкуване и прилагане на настоящото споразумение, както и спазването на задълженията, произтичащи от настоящото споразумение, от съществено значение е да се определят разпоредби, които уреждат цялостното управление, по-специално задължителни правила за уреждане на спорове и за изпълнение, които изцяло зачитат автономността на съответните правни системи на Съюза и на Обединеното кралство, както и статуса на Обединеното кралство като трета държава, КАТО ПРИЗНАВАТ, че за постигането на организирано оттегляне на Обединеното кралство от Съюза е необходимо също така да се установят в отделни протоколи към настоящото споразумение трайни договорености във връзка с много специфичните ситуации, свързани с Ирландия/Северна Ирландия и със зоните на суверенните бази в Кипър, КАТО ПРИЗНАВАТ също така, че за организираното оттегляне на Обединеното кралство от Съюза е необходимо също да се определят в отделен протокол към настоящото споразумение конкретните ред и условия по отношение на Гибралтар, които са приложими по-специално по време на преходния период, КАТО ПОДЧЕРТАВАТ, че настоящото споразумение се основава на цялостно равновесие между ползи, права и задължения за Съюза и за Обединеното кралство, КАТО ОТБЕЛЯЗВАТ, че успоредно с настоящото споразумение страните договориха Политическа декларация, очертаваща рамката на бъдещите отношения между Европейския съюз и Обединеното кралство Великобритания и Северна Ирландия, КАТО ИМАТ ПРЕДВИД, че е необходимо както Обединеното кралство, така и Съюзът да предприемат всички необходими стъпки, за да започнат възможно най-скоро след датата на влизане в сила на настоящото Споразумение официалните преговори по едно или повече споразумения, уреждащи бъдещите им отношения, с оглед да се гарантира, доколкото е възможно, че тези споразумения се прилагат от края на преходния период, СЕ СПОРАЗУМЯХА ЗА СЛЕДНОТО: ПЪРВА ЧАСТ ОБЩИ РАЗПОРЕДБИ Член 1 Цел С настоящото споразумение се определят редът и условията за оттеглянето на Обединеното кралство Великобритания и Северна Ирландия („Обединеното кралство“) от Европейския съюз („Съюзът“) и Европейската общност за атомна енергия („Евратом“). Член 2 Определения За целите на настоящото споразумение се прилагат следните определения: а) „право на Съюза“ означава: i) Договорът за Европейския съюз („ДЕС“), Договорът за функционирането на Европейския съюз („ДФЕС“) и Договорът за създаване на Европейската общност за атомна енергия („Договорът за Евратом“), с измененията и допълненията, както и Договорите за присъединяване и Хартата на основните права на Европейския съюз, наричани заедно „Договорите“; ii) общите принципи на правото на Съюза; iii) актовете, приети от институциите, органите, службите или агенциите на Съюза; iv) международните споразумения, по които Съюзът е страна, и международните споразумения, сключени от държавите членки, действащи от името на Съюза; v) споразуменията между държавите членки, сключени в качеството им на държави — членки на Съюза; vi) актовете на представителите на правителствата на държавите членки, заседаващи в рамките на Европейския съвет или на Съвета на Европейския съюз („Съвета“); vii) декларациите, направени в контекста на междуправителствените конференции, които приеха Договорите; б) „държави членки“ означава Кралство Белгия, Република България, Чешката република, Кралство Дания, Федерална република Германия, Република Естония, Ирландия, Република Гърция, Кралство Испания, Френската република, Република Хърватия, Италианската република, Република Кипър, Република Латвия, Република Литва, Великото херцогство Люксембург, Унгария, Република Малта, Кралство Нидерландия, Република Австрия, Република Полша, Португалската република, Румъния, Република Словения, Словашката република, Република Финландия и Кралство Швеция; в) „гражданин на Съюза“ означава лице, което има гражданство на държава членка; г) „гражданин на Обединеното кралство“ означава гражданин на Обединеното кралство съгласно определението в Новата декларация на правителството на Обединеното кралство Великобритания и Северна Ирландия от 31 декември 1982 г. относно определението на понятието „граждани“ (1) заедно с Декларация № 63, приложена към Заключителния акт на Междуправителствената конференция, която прие Договора от Лисабон (2); д) „преходен период“ означава периодът, предвиден в член 126. е) „ден“ означава календарен ден, освен ако не е предвидено друго в настоящото споразумение или в разпоредбите на правото на Съюза, станали приложими по силата на настоящото споразумение. Член 3 Териториален обхват 1. Освен ако в настоящото споразумение или в правото на Съюза, станало приложимо по силата на настоящото споразумение, не е предвидено друго, всяко позоваване в настоящото споразумение на Обединеното кралство или на неговата територия се разбира като позоваване на: а) Обединеното кралство; б) Гибралтар, доколкото правото на Съюза е било приложимо по отношение на Гибралтар преди датата на влизане в сила на настоящото споразумение; в) Англо-нормандските острови и остров Ман, доколкото правото на Съюза е било приложимо по отношение на Англо-нормандските острови и остров Ман преди датата на влизане в сила на настоящото споразумение; г) зоните на суверенните бази на Акротири и Декелия в Кипър, доколкото е необходимо за осигуряването на изпълнението на ангажиментите, предвидени в Протокола за зоните на суверенните бази на Обединеното кралство Великобритания и Северна Ирландия в Кипър, приложен към Акта относно условията за присъединяване на Чешката република, Република Естония, Република Кипър, Република Латвия, Република Литва, Република Унгария, Република Малта, Република Полша, Република Словения и Словашката република към Европейския съюз; д) отвъдморските страни и територии, изброени в приложение II към ДФЕС, които имат специални отношения с Обединеното кралство (3), когато разпоредбите на настоящото споразумение се отнасят до специалните договорености за асоцииране на отвъдморските страни и територии към Съюза. 2. Освен ако в настоящото споразумение или в правото на Съюза, станало приложимо по силата на настоящото споразумение, не е предвидено друго, всяко позоваване в настоящото споразумение на държавите членки или на тяхната територия се разбира като отнасящо се до териториите на държавите членки, за които се прилагат Договорите, както е предвидено в член 355 от ДФЕС. Член 4 Методи и принципи, свързани с действието, изпълнението и прилагането на настоящото споразумение 1. Разпоредбите на настоящото споразумение и разпоредбите на правото на Съюза, станали приложими по силата на настоящото споразумение, пораждат по отношение на и в Обединеното кралство същите правни последици като тези, които пораждат в рамките на Съюза и неговите държави членки. В съответствие с това юридическите или физическите лица могат по-специално да се позовават пряко на разпоредбите, съдържащи се или посочени в настоящото споразумение, които отговарят на условията за пряко действие съгласно правото на Съюза. 2. Обединеното кралство гарантира спазването на параграф 1, включително що се отнася до правомощията, необходими на съдебните и административните органи на Обединеното кралство да не прилагат непоследователни или несъвместими национални разпоредби посредством националното първично законодателство. 3. Разпоредбите на настоящото споразумение, които се позовават на правото на Съюза или на неговите понятия или разпоредби, се тълкуват и прилагат в съответствие с методите и общите принципи на правото на Съюза. 4. При изпълнението и прилагането им разпоредбите на настоящото споразумение, които се позовават на правото на Съюза или на неговите понятия или разпоредби, се тълкуват в съответствие с приложимата съдебна практика на Съда на Европейския съюз, постановена преди края на преходния период. 5. При тълкуването и прилагането на настоящото споразумение съдебните и административните органи на Обединеното кралство надлежно вземат предвид съответната съдебна практика на Съда на Европейския съюз, постановена след края на преходния период. Член 5 Добросъвестност Съюзът и Обединеното кралство си съдействат взаимно при пълно взаимно зачитане и добросъвестност при изпълнението на задачите, произтичащи от настоящото споразумение. Те предприемат всички подходящи мерки, общи или конкретни, за да гарантират изпълнението на задълженията, произтичащи от настоящото споразумение, и се въздържат от всякакви мерки, които биха застрашили постигането на целите на настоящото споразумение. Настоящият член не засяга прилагането на правото на Съюза съгласно настоящото споразумение, по-специално принципа на лоялно сътрудничество. Член 6 Позовавания на правото на Съюза 1. С изключение на четвърта и пета част, освен ако в настоящото споразумение не е предвидено друго, всяко позоваване в настоящото споразумение на правото на Съюза се разбира като позоваване на правото на Съюза, включително в неговата изменена или заменена версия, така както е приложимо в последния ден от преходния период. 2. Когато в настоящото споразумение се прави позоваване на актове на Съюза или разпоредби от тях, това позоваване, когато е уместно, се счита, че включва позоваване на правото на Съюза или разпоредби от него, които въпреки че са заменени или отменени с посочения акт, продължават да се прилагат в съответствие с посочения акт. 3. За целите на настоящото споразумение позоваванията на разпоредби на правото на Съюза, станали приложими по силата на настоящото споразумение, се разбират като включващи позовавания на съответните актове на Съюза, които допълват или изпълняват тези разпоредби. Член 7 Позовавания на Съюза и на държавите членки 1. За целите на настоящото споразумение всички позовавания на държавите членки и на компетентните органи на държавите членки в разпоредби на правото на Съюза, станали приложими по силата на настоящото споразумение, се разбират като включващи Обединеното кралство и неговите компетентни органи, освен по отношение на: а) предлагането на кандидатурата, назначаването или избирането на членове на институциите, органите, службите и агенциите на Съюза, както и участието в процеса на вземане на решения и присъствието на заседанията на институциите; б) участието в процеса на вземане на решения и в управлението на органите, службите и агенциите на Съюза; в) присъствието на заседанията на комитетите, посочени в член 3, параграф 2 от Регламент (ЕС) № 182/2011 на Европейския парламент и на Съвета (4), на експертните групи на Комисията или на други подобни структури, или на заседанията на експертни групи или други подобни структури на органи, служби и агенции на Съюза, освен ако в настоящото споразумение не е предвидено друго. 2. Освен ако в настоящото споразумение не е предвидено друго, всяко позоваване на Съюза се разбира като включващо Евратом. Член 8 Достъп до мрежи, информационни системи и бази данни Освен ако в настоящото споразумение не е предвидено друго, в края на преходния период Обединеното кралство престава да има право на достъп до всички мрежи, информационни системи и бази данни, създадени въз основа на правото на Съюза. Обединеното кралство предприема подходящи мерки, за да гарантира, че няма достъп до мрежи, информационни системи или бази данни, до които то вече няма право на достъп. ВТОРА ЧАСТ ПРАВА НА ГРАЖДАНИТЕ ДЯЛ I Общи разпоредби Член 9 Определения За целите на настоящата част и без да се засяга дял III се прилагат следните определения: а) „членове на семейството“ означава следните лица, независимо от тяхното гражданство, които попадат в рамките на персоналния обхват, предвиден в член 10 от настоящото споразумение: i) членове на семейството на граждани на Съюза или членове на семейството на граждани на Обединеното кралство по смисъла на член 2, точка 2 от Директива 2004/38/ЕО на Европейския парламент и на Съвета (5); ii) лица, различни от тези, определени в член 3, параграф 2 от Директива 2004/38/ЕО, чието присъствие се изисква от граждани на Съюза или граждани на Обединеното кралство, за да не бъдат лишени тези граждани на Съюза или граждани на Обединеното кралство от право на пребиваване, предоставено по силата на настоящата част; б) „погранични работници“ означава граждани на Съюза или граждани на Обединеното кралство, които упражняват икономическа дейност в съответствие с член 45 или 49 от ДФЕС в една или повече държави, в които не пребивават; в) „приемаща държава“ означава: i) по отношение на граждани на Съюза и членове на техните семейства —Обединеното кралство, ако те са упражнили правото си на пребиваване там в съответствие с правото на Съюза преди края на преходния период и продължават да пребивават там след това; ii) по отношение на граждани на Обединеното кралство и членове на техните семейства — държавата членка, в която те са упражнили правото си на пребиваване в съответствие с правото на Съюза преди края на преходния период и в която продължават да пребивават след това; г) „държава на месторабота“ означава: i) по отношение на граждани на Съюза — Обединеното кралство, ако те са извършвали стопанска дейност като погранични работници преди края на преходния период и продължават да извършват стопанска дейност след това; ii) по отношение на гражданите на Обединеното кралство — държавата членка, в която те са извършвали стопанска дейност като погранични работници преди края на преходния период и в която продължават да извършват стопанска дейност след това; д) „право на упражняване на родителски права“ означава правото на упражняване на родителски права по смисъла на член 2, точка 9 от Регламент (ЕО) № 2201/2003 на Съвета (6), включително правото на упражняване на родителски права, придобито по силата на съдебно решение, на закона или на споразумение, пораждащо правни последици. Член 10 Персонален обхват 1. Без да се засяга дял III, настоящата част се прилага за следните лица: а) граждани на Съюза, които са упражнили правото си на пребиваване в Обединеното кралство в съответствие с правото на Съюза преди края на преходния период и продължават да пребивават там след това; б) граждани на Обединеното кралство, които са упражнили правото си на пребиваване в държава членка в съответствие с правото на Съюза преди края на преходния период и продължават да пребивават там след това; в) граждани на Съюза, които са упражнили правото си като погранични работници в Обединеното кралство в съответствие с правото на Съюза преди края на преходния период и продължават да го упражняват след това; г) граждани на Обединеното кралство, които са упражнили правото си като погранични работници в една или повече държави членки в съответствие с правото на Съюза преди края на преходния период и продължават да го упражняват след това; д) членове на семейството на лицата, посочени в букви а) — г), при условие че отговарят на едно от следните условия: i) те са пребивавали в приемащата държава в съответствие с правото на Съюза преди края на преходния период и продължават да пребивават там след това; ii) те са били пряко свързани с лице, посочено в букви а) — г), и са пребивавали извън приемащата държава преди края на преходния период, при условие че отговарят на условията, определени в член 2, точка 2 от Директива 2004/38/ЕО към момента, в който поискат разрешение за пребиваване съгласно настоящата част, за да се присъединят към лицето, посочено в букви а) — г) от настоящия параграф; iii) те са били родени или законно осиновени от лица, посочени в букви а) — г), след края на преходния период, във или извън приемащата държава, и отговарят на условията, определени в член 2, точка 2, буква в) от Директива 2004/38/ЕО към момента, в който поискат разрешение за пребиваване съгласно настоящата част, за да се присъединят към лицето, посочено в букви а) — г) от настоящия параграф, и отговарят на едно от следните условия: — и двамата родители са лица, посочени в букви а) — г); — единият от родителите е лице, посочено в букви а) — г), а другият е гражданин на приемащата държава; или — единият от родителите е лице, посочено в букви а) — г), и има изключително или споделено право на упражняване на родителски права върху детето, в съответствие с приложимите норми на семейното право на държава членка или на Обединеното кралство, включително приложимите норми на международното частно право, по силата на които правото на упражняване на родителски права, установено съгласно правото на трета държава, се признава в държавата членка или в Обединеното кралство, по-специално във връзка с висшия интерес на детето, и без да се засяга нормалното действие на такива приложими норми на международното частно право (7); е) членове на семейството, които са пребивавали в приемащата държава в съответствие с членове 12 и 13, член 16, параграф 2 и членове 17 и 18 от Директива 2004/38/ЕО преди края на преходния период и продължават да пребивават там след това.
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Document Type : Review Article 1 Division Microbiology, Department of Molecular and Cell Biology, Faculty of Basic Sciences, Lahijan branch, Islamic Azad University(IAU), Lahijan, Gilan, IR. Iran The aim of this study is introduction on microbials as an effective agent in the human body. Microbial (symbiotic microorganisms) means the general and universal ecosystem of riches, all genes and masses of micronutrients, regardless of their genera and species, are referred to in a particular section. The symbiotic microbials have a symbiotic relationship with host creatures. This means that these microbes can also be partners, both pathogens. For example, all bacteria, fungi and other types of germs that live natively in the human skin are called microbiotics. The largest microbial of the human body is the microbioum of the digestive tract and, in particular, the large intestine. This term, although used more in medicine, is also valid in other branches of microbiology. They play an important role in health and disease. And trillions of bacteria, called microbials, that make up our bodies in our societies, involve the release of chemicals in the method of digestion, the delivery of medication, and the development and development of diseases such as heart disease, metabolic disorders (metabolism), or even cancer progression. Arunima, A, Das, JK, Suar, M. (2019). Gut Microbes in Liver Diseases: Dietary Intervention for Promoting Hepatic Health.  Dietary Interventions in Gastrointestinal Diseases. Elsevier. p: 117-31. Clemente, JC, Ursell, LK, Parfrey, LW, Knight, R. (2012). The impact of the gut microbiota on human health: an integrative view. Cell., 148(6):1258-1270. Chowdhury, R, Sahu, GK, Das, J. (1996). Stress response in pathogenic bacteria. J. Biosci., 21(2):149-160. Chang, CP, Hsiao, CT, Fann, WC. (2019). Risk factors associated with bacteremia correlated with mortality in patients with acute bacterial skin and skin structure infection. Intern. Emerg. Med., 14(2):259-264. Chang, I, Cho, GC. (2019). Shear strength behavior and parameters of microbial gellan gum-treated soils: from sand to clay. Acta Geotechnica., 14(2):361-375. Gibson, GR, Roberfroid, MB. (1995). Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. nutr., 125(6):1401-1412. Huang, C, Zeng, Y, Luo, X, Ren, Z, Tang, B, Lu, Q, Gao, S, Wang, S, Mai, B. (2019). In Situ Microbial Degradation of PBDEs in Sediments from an E-Waste Site as Revealed by Positive Matrix Factorization and Compound-Specific Stable Carbon Isotope Analysis. Environ. Sci. Technol., 53(4):1928-1936. Milkov, AV. (2018). Secondary microbial gas. Hydrocarbons, Oils and Lipids: Diversity, Origin, Chemistry and Fate. p: 1-10. Macfarlane, S, Dillon, J. (2007). Microbial biofilms in the human gastrointestinal tract. J. Appl. Microbiol., 102(5):1187-1196. Martínez, JL, Baquero, F. (2002). Interactions among strategies associated with bacterial infection: pathogenicity, epidemicity, and antibiotic resistance. Clin. Microbial. Rev., 15(4):647-679. Nitschke, M, Silva, SSE. (2018). Recent food applications of microbial surfactants. Crit. Rev. Food Sci. Nutr., 58(4):631-638. Preininger, C, Sauer, U, Bejarano, A, Berninger, T. (2018). Concepts and applications of foliar spray for microbial inoculants. Appl. Microbiol. Biotechnol., 102(17):7265-7282. Parmar, ND, Shukla, SR. (2019). Decolourization of dye wastewater by microbial methods-A review. Indian J. Chem. Technol. (IJCT)., 25(4):315-323. Roberts, CA, Buikstra, JE. (2019). Bacterial infections.  Ortner's Identification of Pathological Conditions in Human Skeletal Remains: Elsevier. p:321-439. Toczyłowska-Mamińska, R, Szymona, K, Król, P, Gliniewicz, K, Pielech-Przybylska, K, Kloch, M, Logan, BE.(2018). Evolving microbial communities in cellulose-fed microbial fuel cell. Energies, 11(1):124. Yousuf, B, Mishra, A. (2019). Exploring Human Bacterial Diversity Toward Prevention of Infectious Disease and Health Promotion.  Microb. Diver. Genom. Era, p: 519-533. Yeoh, YK, Chen, Z, Hui, M, Wong, MC, Ho, WC, Chin, ML, Ng, SC, Chan, FKL, Chan, PKS. (2019). Impact of inter-and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles. Peer J., 7:e6172. Yeo, J, Kim, T, Jang, J, Yang, Y. (2018). Practical maximum-power extraction in single microbial fuel cell by effective delivery through power management system. Energies, 11(9):2312. Verran, J, Redfern, J, Moravej, H, Adebola, Y. (2019). Refreshing the public appetite for ‘good bacteria’: menus made by microbes. J. Biol. Educat., 53(1):34-46. Wang, Y, Li, L, Xiong, R, Guo, X, Liu, J. (2019). Effects of aeration on microbes and intestinal bacteria in bioaerosols from the BRT of an indoor wastewater treatment facility. Sci. Total Environ., 648:1453-1461. Wu, X, Shi, Z, Zou, L, Li, CM, Qiao, Y. (2018). Pectin assisted one-pot synthesis of three dimensional porous NiO/graphene composite for enhanced bioelectrocatalysis in microbial fuel cells. J. Power Sou., 378:119-124. Zhao, X, Huang, J, Lu, J, Sun, Y. (2019). Study on the influence of soil microbial community on the long-term heavy metal pollution of different land use types and depth layers in mine. Ecotoxicol. Environ. Safety, 170:218-226.
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\section{Powers of 2 not containing Digit Power of 2} Tags: Powers of 2, 65,536 \begin{theorem} $2^{16} = 65 \, 536$ is the only known power of $2$, up to $2^{31 \, 000}$, whose digits do not contain $1$, $2$, $4$ or $8$. \end{theorem} \begin{proof} This has been demonstrated by an exhaustive search. {{qed}} \end{proof}
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package com.naci.sample.themetmuseum.common import androidx.lifecycle.ViewModel import kotlinx.coroutines.flow.Flow import kotlinx.coroutines.flow.MutableStateFlow import kotlinx.coroutines.flow.map abstract class BaseViewModel : ViewModel() { private val _inProgressCount = MutableStateFlow(0) // TODO : This must be StateFlow val progressState: Flow<Boolean> get() = _inProgressCount.map { progressCount -> progressCount > 0 } fun increaseInProgressCount() { _inProgressCount.value = _inProgressCount.value.plus(1) } fun decreaseInProgressCount() { _inProgressCount.value = _inProgressCount.value.minus(1) } }
common_corpus
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Storyboard to Commercial: Richard Row for Mio ‘Changes’ One of the only Youtube commercials I’d actually leave on (as opposed to toss my laptop into the garbage bin) when it comes on; the series of Mio’s commercials were hilarious. Seeing the original boards for the commercial also reveals a few jokes that didn’t make the cut. The campaign was conceived by copywriter Alexis Bronstorph, Troy Palmer and Art Director Mike Lee at Taxi2 in Canada. Directed by Benji Weinstein (Steam Films). Till date it’s been seen over a million times on Youtube. I’ve left in a few screenshots for comparisons as it’s interesting to see what was left in and what was cut. Enjoy! Take note of how well the storyboard sells the idea; Richard did a really great job of bringing the crazy ideas of the agency to life. Its a great example of why it’s a good idea to invest in a good illustrator for presenting ideas. To see if Richard is available or not; visit my site of the world’s best storyboard artists. See more of his work at his portfolio site. Want more ‘Storyboard to Commercial’ posts? Storyboard to Commercial: Tim Hortons by Greg Banning Storyboard to Commercial: Call of Duty by Dan Milligan Advertising Agency: Taxi 2, Canada Creative Director: Lance Martin Art Director: Mike Lee Copywriter: Alexis Bronstorph, Troy Palmer French Writer: Tanya Henri VP, Integrated Production: Cynthia Heyd Agency Producer: Ben Sharpe French Agency Producer: Anick Rozon Group Account Director: Daniel Shearer Account Manager: Zak Usher Production Company: Steam Films Director: Benji Weinstein Director Of Photography: Tico Poulakakis Production Designer: Michael Walker Casting Director: Andrew Hayes / Powerhouse Casting Line Producer: Andrew Graham Executive Producer: Krista Marshall Editorial Company: Posterboy Edit Editor: Griff Henderson Assistant Editor: Danica Pardo Executive Producer: Michelle Lee Colour Facility: Alter Ego Colourist: Wade Odlum Executive Producer: Greg Edgar Post Production: The Vanity VFX Artist: Sean Cochrane Executive Producer: Stephanie Pennington Audio House: RMW Music CEO/Producer: Ted Rosnick Executive Producer: Jeff Cohen
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This Eco-Warrior Shower Curtain Forces You to Get Out of the Shower After 4 Minutes Shower time goes from quick to indeterminable, depending on the time of day, our mood, or perhaps even the particular brand of shower gel or shampoo we choose to use or try out. However, rarely do we ponder the amount of water that is consumed. Confronting Water Shortage The issue of global shortages of freshwater has occupied serious scientific discussions since the dawn of the new millenium; however, in the last few years reports and warnings about water shortages have increased in even more alarming numbers. Often in the media, scientists and journalists lament the struggles of agricultural communities in developing or undeveloped countries, while the reality of what is happening in terms of the same issue in developed countries is largely underrepresented, leaving a gap in the conversation. This summer in Italy, for instance, record high temperatures combined with subsequent drought brought increased demands for water, with Health Minister Beatrice Lorenzin stressing, “An eventual suspension of the supply of water in Rome could seriously compromise the level of hygiene of all the accommodation structures, restaurants and public offices. But above all, it could seriously compromise the provision of essential health services." Echoing the European Environment Agency (EEA)’s report findings on Water Stress Areas throughout Europe, Green Cross International Founding President Mikhail Gorbachev spells out the challenges very clearly: "Continuation of water consumption at 20th Century rates is no longer possible...[as politics and the economy are tied to water consumption,] we, therefore, need to rethink the goals of economic development.” A Design With A Message London-based artist Elisabeth Buecher, the designer of the inflatable curtains, explains the reasoning behind the design: “I looked at the environmental issue of excessive water consumption. I designed a series of water-saving shower curtains which inflate after four minutes spent under the water, taking over the space and discouraging long water-wasting showers.” With this fun, but impactful design, she hopes to bring a broader awareness to the public about issues of water consumption. Currently, there are two models available: Spiky and Trap. As the names suggest, the slight discomfort experienced by the shower curtain mirrors the discomfort experienced by those for whom water shortages are a daily reality. The artist hopes the design will create a conversation around these issues. A Trend Among Artists Buecher’s designs are part of a larger shift in the artistic community in the last decade, as more and more artists take on environmental issues, incorporating them as major parts of their work. The term Ecological Art has been coined to describe this broad movement. Diverging from Environmental Art, the aim of Ecological Artists to combine art with platform: the main purpose of the creation of their art is to have a conscious impact on environmental activism. We use cookies to ensure you get the best experience on our website. If you continue using our website, we'll assume that you are happy to receive all cookies on the Interesting Engineering website. Please review our Privacy Policy for more information and/or to change your cookie settings at any time.
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Tuesday, April 7, 2009 Ataraxia - The Unexplained (1975) The Unexplained - Electronic Musical Impressions Of The Occult By Ataraxia is another Moog masterwork composed by the great synthesizer pioneer Mort Garson, picking up where Black Mass by Lucifer, from 1971, left off. 1. Tarot 2. Sorcerer 3. Deja Vu 4. Astral Projection 5. Seance 6. I Ching 7. Cabala 8. The Unexplained 9. Wind Dance Composed by Mort Garson. Monday, April 6, 2009 Lucifer - Black Mass (1971) How Mort Garson Inspired Nightmare City Halloween This is the album that started it all for me! In 1973 I worked at "Scream In The Dark", Tulsa's ultimate Halloween haunted house attraction. Every night, all night long, the most incredible music played throughout the entire house. It was a cassette tape, looping the album "Black Mass" by Lucifer (Mort Garson), an incredible electronic music tour de force. I thought it was the most incredible music I had ever heard and that's when my love of Halloween music was born. 1. Solomon's Ring 2. The Ride Of Aida (Voodoo) 3. Incubus 4. Black Mass 5. The Evil Eye 6. Exorcism 7. The Philosopher's Stone 8. Voices Of The Dead (The Medium) 9. Witch Trial 10. ESP Composed by Mort Garson.
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/* * (C) Copyright 2006-2011 Nuxeo SA (http://nuxeo.com/) and others. * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * * Contributors: * Florent Guillaume */ package org.nuxeo.ecm.core.storage.dbs; import org.nuxeo.ecm.core.storage.ClusterInvalidator; /** * Encapsulates cluster node DBS invalidations management. * <p> * There is one cluster invalidator per cluster node (repository). * * @since 8.10 */ public interface DBSClusterInvalidator extends ClusterInvalidator<DBSInvalidations> { /** * Initializes the cluster invalidator. * * @param nodeId the cluster node id * @param repositoryName the repository name */ void initialize(String nodeId, String repositoryName); }
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AirSpaceMag.com Flameout Why the fire in a perfectly healthy jet engine can die. In the early afternoon of May 24, 1988, TACA Flight 110, a Salvadoran Boeing 737 arriving from Belize, was picking its way among thunderstorms ringing New Orleans when the unthinkable happened: Both of the airliner’s jet engines quit. Frantically, the crew members tried to restart them. At first they thought they had succeeded: Okay, one crew member radioed to controllers as the craft descended through 4,000 feet, we’ve got both engines back now. But relief evaporated less than a minute later. The engines would not accelerate from idle speed, and dangerously rising tailpipe temperatures forced the crew to shut them down again.I don’t think that I will make it, I don’t have any power on the engines here sir, so I guess we having to go down, we have to go down, we declare emergency.... TACA 110, there is the interstate highway directly ahead of you.... I don’t believe we gonna be able to make it there sir, we’re at 2,000 and we’re losing altitude.... The only thing I do right now is make a 360 and I’ll land over the water sir. TACA 110, I show your altitude now 700 feet. Seven minutes later another airplane, at the request of the air traffic controller, flew over the area where the 737’s radar target had disappeared. The pilot caught sight of the airliner incongruously parked on the embankment of a levee beside Lake Borgne, its escape chutes deployed. With remarkable airmanship, Captain Carlos Dardano had dead-sticked the 737 onto a mile-long patch of rain-soaked earth. The airplane and its passengers were unharmed. What happened to TACA 110 is called a flameout. The term is casually used for any failure in a turbine engine, but its technical meaning is more narrow: power loss not associated with a mechanical failure. A flameout of one kind or another is thought to occur once in every 100,000 non-military flights. Three things are needed to keep a jet engine going: fuel, air, and the heat to make them burn. Removing any of the three can cause a flameout. In the case of TACA 110, what was taken away was the “activation energy”—the heat. The engines had been throttled back for descent, and their supply of internal heat was minimal; heavy rain and hail simply doused the fire. The event was not unique. Nine months earlier, an Air Europe 737 descending through rain and hail over Thessaloniki, Greece, had suffered a double flameout. In that case, the crew managed to restart the engines and land without trouble. In 2002, a Garuda Indonesia 737, also descending among thunderstorms, suffered a double flameout over Java. Its crew ditched the airplane in a river; one person died, and there were a dozen serious injuries. Water and ice aren’t the only things that can turn off the fire in a jet engine. Unexpectedly, so can fuel. Obviously, running out of fuel is a good way to stop an engine, but too much fuel can have the same effect, if it comes from the wrong place. Walt Larimer, a retired U.S. Air Force navigator, remembers an incident from the late 1950s in Morocco. An F-100 pilot, a novice at aerial refueling, couldn’t get hooked up to Larimer’s KB-50J tanker. It took many attempts, but the pilot finally managed to engage the refueling drogue, only to fracture the coupling at the end of the fueling hose a moment later. Jet fuel began to stream out. The fighter, whose engine air intake is in its nose, dropped back and inadvertently slurped up some JP-4. A muffled explosion could be heard from inside the F-100, and flames emerged from its front and rear ends simultaneously. The fighter, its engine spooling down, dropped from sight while a fellow pilot who had been waiting for his turn at the hose shouted restart instructions. Larimer later learned that the hapless pilot of the stricken jet failed to restart the engine. But he managed to glide back to his base and make a successful dead stick landing on the runway—a semi-miraculous accomplishment in an F-100. Only a military pilot during a refueling operation is likely to encounter stray JP-4. For the rest of us, the atmosphere can contain even more insidious antagonists. Since 1980, the year Mount St. Helens in Washington state erupted, there have been at least 100 instances of airliners encountering clouds of volcanic ash, often hundreds of miles from the source; the clouds have done more than $250 million in damage to airplanes that unwittingly entered them. In two cases, passenger-carrying Boeing 747s have lost all power in all four engines. The first, a 1982 British Airways flight, glided from 37,000 to 14,000 feet in darkness over the south Pacific Ocean before its crew managed to restart the engines. The second, involving a KLM airplane in 1989, took place in Alaska; there too the pilots managed to restore partial power and land safely. Volcanic ash, which is highly abrasive, sandblasts an airplane’s skin and windows, requiring extensive repairs. Inside the engines, its effects are more varied. Ash grinds away compressor blades and reshapes the airfoils of turbine blades and guide vanes by filling up their concave surfaces. It melts and fuses on the perforated walls of combustors. It plugs up the delicate shrouds and vanes of injectors, whose job is to vaporize the fuel and mix it with just the right amount of air to ensure ignition in the generally over-lean atmosphere of the combustor. All these effects are most disruptive at high altitude, where air is thin and the conditions of combustion are most critical; crews were able to get relights only after long and harrowing glides. Like all internal combustion engines, a jet engine compresses air, then adds fuel and ignites it. The burning gases in the combustion chamber rush toward the open back end at high speed. On the way, they deliver power—in large engines tens of thousands of horsepower—to a turbine that drives the compressor at the front. The Newtonian equal-and-opposite reaction to gas shooting out the back is the force pushing the engine forward. The whole process sounds somewhat chancy, and is. Getting a jet engine to run, then keeping it running and under control, is not a simple matter. The early notebooks of Frank Whittle, the Englishman who invented the modern jet engine (independently of, but simultaneously with, a German, Hans Pabst von Ohain), are full of descriptions of dramatically brief tests, shrieking runaways, overheated burners, and melting turbine blades. Air, fuel, and engine speed must remain balanced within certain limits; otherwise, the fire either goes out or consumes the engine around it. The immensely reliable modern jet engine is the fruit of millions of hours and billions of dollars spent getting all the parts just right: the shapes of compressor and turbine blades and the stator blades that guide the flow between them, the lubrication and seals, and the geometry of fuel injectors and igniters. Besides perfecting these components, research has produced materials for the “hot section” in and downstream of the burners, where small parts made of exotic alloys with a melting point of 2,200 degrees Fahrenheit survive, thanks to elaborate and ingenious methods of insulating and cooling, in a steady bath of 3,000-degree gas. Nevertheless, seemingly small things can still make an engine quit. Very hot or disturbed intake air can do it. Adverse interactions between engines and armament have plagued many military jets. The engines of the A-10 “Warthog,” which are mounted on pylons beside the rear fuselage, suck up much of the gas that blows back from the muzzle of its 4,000-round-per-minute Gatling gun. Occasionally, as Air Force Captain Rusty Gideon learned the hard way (see “All Because of a Little Hot Air,” right), ingestion of gun gas can shut engines down. The F-94 Starfire, a 1950s Lockheed fighter based on the F-80 Shooting Star, would sometimes flame out after firing salvos of rockets, which distorted the flow of air into its side-mounted engine air intakes. Even the relatively modern F-14 experienced interactions between its guns and its Pratt & Whitney TF-30 engines; its gun muzzles were retrofitted with special gas diffusers to alleviate the problem. Actually, the 21,000-pound-thrust TF-30 engine was notoriously prone to flameout for any number of reasons, including—rather inopportunely in the carrier-based Vought A-7, which had only one of them—the jolt of a catapult launch. Improper inlet flow is said to be “distorted” because jet engines are happiest when the air entering the engine is going in the same direction, and at the same speed, at all points on the engine face. For the short inlets of airliner nacelles and the narrow range of flight attitudes they experience, uniform flow is easy to achieve. Fighters, however, present special challenges to designers. Their engines are normally buried within the fuselage and behind the cockpit, and air has to travel through ducts to reach them. Fighters maneuver violently. Inlets placed alongside the fuselage, like those of the F-14 and F-15, ingest distorted flow whenever the airplane’s nose swings to the right or left relative to the flight path. The F-16’s intake placement—like that of the Eurofighter, beneath the forward fuselage—tolerates maneuvering better. Compressor stall—technically called surge—is a much more frequent phenomenon than flameout, and may lead to flameout. Surge occurs when engine speed, airflow, and fuel supply get out of balance and the required distribution of pressure throughout the engine is disturbed. Some or all of the blades in the compressor experience an aerodynamic stall, like that of the wing of an airplane when its nose is held too high. The abrupt pressure drop can generate one or more extremely loud bangs, and, in particularly dramatic cases, the flame from the combustor, no longer forced backward by incoming compressed air, can shoot out the front of the engine. Usually the engine recovers on its own. Frank Smith, a former Navy A-7 pilot, recalls a particularly startling compressor stall that happened during a practice dogfight in 1970. His opponent “went from 250 yards astern to 100 yards ahead in about one second while I experienced a complete end-swap and the biggest noise I ever heard from an aircraft that remained in one piece. But the engine kept running and rpm barely dropped before I was able to regain control. Hell, I really didn’t do anything but hang on.” Surges do not always clear automatically; sometimes they are “locked in,” rotating in place within the compressor. Then, rising temperatures in the hot section force the pilot to shut the engine down. Loss of an engine affects other aircraft systems—hydraulic, pressurization, and electrical—all of which are supplied by engine-driven components. There are backup systems, but restarts can still be surprisingly difficult because of the distracting secondary effects of losing power. Even within its operating envelope, however, the higher a jet flies, the narrower the “surge margins” that define how far conditions within the engine can stray from the optimum before it quits running. At sufficiently high altitudes, jet engines flame out simply because they run out of oxygen. Not all flameouts are accompanied by noise or vibration or by any obvious triggering event. In some cases, especially on multi-engine airplanes, one engine may spool down unnoticed by the pilot, while autopilot and autothrottle conspire to mask the thrust asymmetry. In a few instances, crews have temporarily lost control because they failed to realize that one engine has stopped producing thrust. A fatal accident in 2004 illustrates the potentially dire consequences of inattention to engine parameters and the unexpected difficulties that can beset restart attempts. Two pilots flying a Canadair regional jet to its next departure location decided, on a lark, to take the airplane up to its 41,000-foot ceiling, where neither had ever been. They programmed the autopilot to climb at a fixed rate. As the airplane ascended into ever thinner air and the engines produced less and less thrust, the autopilot had to keep reducing speed in order to maintain the commanded climb rate. The crew did not notice anything was wrong until both engines flamed out. The pilots turned to the restart checklist, which first required descending rapidly to a lower altitude. Meanwhile the engines spooled down, and unequal cooling of closely fitting seals in the compressor caused them to bind—a condition now dubbed “core lock.” The engines would not spool up, either from windmilling or with the help of the auxiliary power unit. By the time the crew realized that the engines would not come back, they were too low to reach the nearest landing field. The aircraft crashed a couple of miles short of a runway; both pilots were killed. Engines that have flamed out and that have not been damaged by, say, a violent compressor surge can, in principle at least, be restarted. The difficulty of restarting, and the time it takes, depend on several factors, one of which is how much the engine has spooled down. With sufficiently high forward speed and sufficiently low altitude—generally above 250 knots and below 25,000 feet—engines can windmill up to a speed sufficient to permit ignition; then they gradually bootstrap back to operating speed and compression. Although jets, like any airplane, can glide without power—airliners can progress 10 miles or more horizontally for every mile of altitude they give up—the speed required for a windmilling start is much higher than the best glide speed, and so altitude melts away rapidly during restart efforts. Military jets are regularly tested for restart ability—for example, after an engine upgrade or modification. In twin-engine airplanes it’s routine work, but when an airplane has only one engine to begin with, it can occasionally get tense. Art Nalls, now retired from the Marine Corps, recalls a wintertime test of a TA-4J—a training version of the single-engine A-4 Skyhawk—at Edwards Air Force Base in California. The giant lake bed, an alternate landing site for space shuttles, is normally bone dry, but recent rains had soaked the ground and left it largely flooded. The test card called for restarts at selected points along the edge of the restart envelope; if the engine failed to relight, Nalls would move to the “heart of the envelope,” where the engine was considered sure to start. “One of the last points was a low-altitude, slow-airspeed point that left little margin for error,” he remembers. “Only a small portion of the lake bed was available for landing, and it was soft. Quite possibly the airplane could flip over. But it was legally usable and met the criteria of our test plan, so we elected to continue. We were almost done with the project, everything had worked normally so far, and get-home-itis had started to set in.” Already at a low altitude when the test began, Nalls found it impossible to restart the engine. Only when he was below 1,000 feet, seconds away from a landing on the muddy lake bed, did the engine finally relight. It later turned out that the cause of the trouble had been a malfunctioning ram air turbine—the backup electrical source for the engine’s igniters. Nalls was a test pilot, and test pilots feel strong pressure to bring back the ship in one piece. Under the same circumstances, a service pilot whose jet had flamed out would long since have ejected. The likelihood of making a successful dead stick landing in a jet fighter is considered so slight that the military services have wavered on whether “flameout approaches” should be taught at all. Though the reliability of jet engines is far better than that of the reciprocating engines that they largely replaced half a century ago, the danger of flameouts hasn’t disappeared. Flameouts are a natural consequence of the way jet engines work. They live on an island of stable operation—a dynamic balance of powerful forces—ringed by a sea of instability.
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Q: Table prefix in pyrocms I am working on a custom multiple delete in pyrocms module,how to use delete in model my code: protected $_table = 'accounts'; public function mulDelete($muldelete) { $sql = 'delete from ' . $this->_table . ' where id IN('.$muldelete. ')'; $query = $this->db->query($sql); } but $this->_table is returning accounts instead of username_accounts,how to check username table prefix in from clause in pyrocms A: $sql = 'delete from ' .'username_'. $this->_table . ' where id IN('.$muldelete. ')'; or protected $_table = 'username_accounts'; or dyamically $CI =& get_instance(); $CI->load->database(); echo $CI->db->dbprefix;
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5 Formas de tratar de reducir as súas débedas e gastos Anyone that has a high level of debt or a number of creditors to pay off each month will know how stressful and difficult financial management can be. Con todo, for those crippling themselves with monthly outgoing as a result of high debt levels there are some steps that could help to reduce the amount that you have to pay out each month, así como a redución total de xuros pagados sobre as súas débedas. 2. Asegúrese de que está consciente de exactamente o que está entrando e saíndo da súa conta cada mes. Tentando xestionar as súas finanzas e priorizar en pagar a débeda é imposible se non manter un control adecuado da súa renda e de saída do. List down every little payment that goes out of your account so you know exactly how much you can afford to spend or put towards clearing your debts a little faster. 3. Consider consolidating your debts. By consolidating smaller debts with one larger loan you can reduce the number of repayments you have to make each month, cut back on the number of creditors to whom you have to pay interest, and dramatically reduce the amount that you pay out each month. For homeowners, a secured loan could be the ideal solution, as this can be spread over a longer period and this helps to keep monthly repayments down. You should be aware though, que, ao tomar o financiamento ao longo dun período máis longo, isto significa que pagar xuros por máis tempo. Con todo, if the interest rate is lass than what you currently pay, and lower monthly payments means that you have more disposable income to spend, it would serve to prevent it from being necessary that you need to take on extra borrowing as you will have spare money each month to either build up savings and be able to afford things which you made want to purchase, with out borrowing additional money.
dclm_baseline
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Guildford · Population Question: What is the population of Guildford? Answer: Guildford, United Kingdom (Administrative unit: England) - last known population is ≈ 143 000 (year 2014). This was 0.222% of total United Kingdom population. If population growth rate would be same as in period 2011-2014 (+1.29%/year), Guildford population in 2020 would be: 154 353*. Population history [1] Annual population change [1981-1991] +0.09 %/year [1991-2001] +0.3 %/year [2001-2011] +0.58 %/year [2011-2014] +1.29 %/year GPS coordinates: 51.236, -0.57 Local time in Guildford: 07:26 Monday GMT0. share this.. Guildford on city and population density map Sources, Notices * Unofficial, calculated population. [1] Sources UK National Statistics The Northern Ireland Statistics and Research Agency General Register Office for Scotland • Philip's geographical digest (1996) For some missing data 1991 and earlier Censuses Local Authorities KS01 Usual resident population 1991-2001
dclm_baseline
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Season 1 Episode 11 The Woman in the Car Aired Thursday 8:00 PM Feb 01, 2006 on FOX Episode Fan Reviews (12) out of 10 565 votes • Another good one In this episode of Bones, the following happens. We see Bones as she does a TV interview, during which she says that she is not planning on having children. Then Booth takes Bones to a crime scene, where a car burnt out is found. They believe that a child was inside of the car and since the child is now missing, they believe he or she has been kidnapped. They have called Bones in to help identify the victim, in order to try to learn who the child is. When they check the bones they learn that the victim gave birth 5 – 8 years ago. They soon believe that they have IDed the victim and that she has an 8 year old son. She and her husband Carl have recently separated. They go to Carl's house, but he isn't there. We then see that US Marshalls are there and that Carl is actually in the Witness Protection Programme. We learn from her sister, that the victim left her husband; because she found out that he was having an affair. Everyone who works in the lab, have to have a security meeting, to make sure that they can work on certain cases. When they examine the victim's body, they find part of an ear inside of her mouth. Soon they believe that she was tortured, in order to find out where he husband was hiding. They soon find Carl holding the people he is suppose to testify against hostage in order to get his son back. They claim that they don't have his son and also don't know where his son is nor do they know who took him. He is taken back into Witness Protection and tells Booth he will only testify if he sees Booth with his son, before he goes into court. Booth gets a box sent to him, and inside in the finger of the missing boy. When Bones looks at it we learn that he was still alive when his finger was cut off. Off of the finger, they learn where they think the boy is being held and so Booth, Bones and SWAT all head there. Once inside a gun fight breaks out and soon they find the little boy in there with his hand wrapped in a bloody towel, since he is now missing one finger. As he is being placed into an ambulance, his father arrives, and he is reunited with his son. • Love this episode I thought that this episode was very revealing especially of the character of Booth. It rounded his character more and gave him some serious action. Loved the remark by his boss (the excellent Jackson) 'Paladin, defender of faith , protector. Suits you Booth' Who can't love Booth as a character and now we see his tender side in his reacting to his son and to the kidnapped child,his understanding of the father's anguish. The episode also reveals yet a little more about his past when he explains his reasons to Brennan for choosing the rural garage, as he would always choose a rural location. When she assumes that it was because he was rescuing a kidnap victim he replies that it was him from whom the victim was being rescued!! Angela is right. Booth is h*t. • this was a good ep in this ep of bones . bones is called to the scene were a women is found burned to a crip but they think she was burned alive . and her kid was taken from her . bones and the team must figure out what really happend when they do some digging they learn that the husband was going to go to the court to be a whitness to tesify that the company sold the miltery bad armor and that they cause lots of deaths and injuries . and so they think that the company had something to do with the wifes death and the kindapping of the boy. they later learn that the mother was excully torched by electric and that is how she died. and they figure out from the things they found on the body that its in a place that has use of electric and a cutting area were they chopped his figure off that booth got in the mail . this wasa great ep i thought • A pretty emotional episode. The beginning was funny, we get to see Brennan giving a interview, and saying that she doesn't want kids. So Booth and Brennan discuss the issue of having kids in this episode, that was a lot of fun to look at. The sad part is that a young boy has been kidnapped, and Booth and Brennan have to go find him, which is by the was the first time we see them searching for someone who is still alive ( hopefully). At one point during this episode, the sent one of the boys fingers to Brennan and Booth. And that is just awful, I mean who cuts a finger of who young boy, that's just sick. Luckily they find the boy in time, and beside that he lost one finger, he is fine. • It gets better... What a terrible situation for the little kid. The bad thing about it is that is true. Poor father, losing his wife and then the son. Happy ending after all. So this is one of those episodes when Booth and Brennan strongly disagree in a topic, this time, was having children, the first of many. It was very uncomfortable for Booth to hear Brennan say all those things about his situation with Parker, she was very rude. But well, they were just getting to know each other and things have changed a lot since this episode. It was weird to find out Angela was married. What was the deal with the phone call made by Brennan when Pickering mentioned that name? I´m still wondering... • Review The case in this episode was okay, but nothing amazing that I would want to go back and watch again anytime soon. Because of the Christmas episode, the case fit right with Booth and his personal involvement in the case. Since we know he has a little boy, there is an extra sense of need to get the kid back for him. In the end though, the case wasnt all that good. The sidestory of the woman interviewing everyone from the State Department led to much of the comedy in this episode, something I enjoyed watching. Her interview with Bones was great. Overall, I thought the episode was solid, but not one of my favorite episodes of the season so far. • Well we learned some more about our characters Okay I really liked this one. Agent Pickering made the episode very interesting. Hodgins was priceless when she called him harmless. I loved when they all demanded lawyers too. Angela was married now that was a shocker. I loved Pickering when she was interviewing Angela because Angela was afraid of saying the wrong thing. Zack was just Zack when Pickering was interviewing him. And Brennan just made a phone call and the review was done. Goodman's interview with Pickering was quite amusing and interesting though. I was freaked out when Booth was sent the finger and having Brennan check it out. Carl Decker was an interesting character himself I loved when he questioned how Brennan had found herself to be with the irrational FBI. Booth and his fatherly instincts also made the episode more enjoyable. Pretty good episode. • eppie number11! haha that interview was so funny. brennan is so bad at it, the poor talk show host was like oh my god im gonna kill you. death glare like whoa. booth has on that sexy trench coat again. yummy. damn he even runs sexy. and beats people up sexy. my god. i hate booth's boss so much. grrrr. in the words of hodgins, but much later in the series, he's such a wank tard. actually i dont even know if that applies here, but you get the idea. angela was so bad at that interview. the lady was like uhh, i hate you. poor angela. hodgins wanted so bad to be interviewed. dont worry, baby, we know you're dangerous. then zach like went crazy and yelled amps and volts at her, then ran away. this is going well, no? oh yea and doctor goodman was just laughing at her. heh heh its so cool when booth talks police speak into his walkie talkie thingy. its like all code and nimber and he talks so fast. just thought i would point that out haha. paladin. it does suit booth. thats cool how they have a code word. what the f*ck. somemone sends booth a fricken finnger, with a note that says "back off" a fricken finger, man. booth was so rattled. i think thats the only time i have seen him freak out like that. well not really freak out, but he certainly wasnt calm. and in the middle of her interrogation, brennan makes a phone call, and gets the review suspended. niice. • An interesting plot, a different one. A different episode, they are looking for a live person this time, off course theres a skeleton in the way to that. We saw character development in the person of Booth and Bones. Actually I tend to see this episode as a little Booth centric: he is a father himself and the tought that something like is happening to that other little boy could happen to his son make him ill, crazy and furious. He knows how the father is feeling and he has a pretty good idea of how scared the kid most be and he cant live with that. It was hilarius to see the way Bones interacts with other people, this time in the form of a journalist that is interviewing her. When we heard her say that she doesnt wanna have children its another piece in Bones´puzzle. She had suffered trought her life, for an orphan the most naturally thing that can happen is for them to shout out the other people out their lives. With the forward episodes we get to almost completely understand her. Finally I´ll say that I loved see Tempe going for help to Booth, she´s really starting to open to him and she trust him above all, it was nice to see that. • Shows that the series has potential The purpose of Bones has been to show the regular documentary drama while putting a slight twist on the characters. The struggle the show has had is the quick and multiple plot changes that are hard to follow and most of the time the secondary character stories are rather pathetic. This episode succeeds because the forensics are kept to a minimum, (though still there are some question as to conclusions they come to) the plot changes are more linear and based more on intuition instead of two paragraphs of facts to move the plot direction. David Boreanaz's Booth has been holding the show up by maintaining a strong singular character while everyone else flounders. He is a valuable resource because is the only one of the group who has a child and the case becomes more personal because of the kidnapped child. This episode shows him making a lot of the analysis and that made for interesting entertainment. It is most prevailant as Brennan and Zach teach the difference between intellect and decisions, where his role as a father proves useful. This time the second story is more watchable then previous ones. The security inspector is going through the staff and annoying just about everyone by researching aspects about their life that even they forgot, or wish to forget. The office scene between the inspector and Brennan made perfect use of Brennan's deadpan personality. If she was used like that more often she would be a much more likeable character. Overall, the drama hit some real notes, the characters reacted in real ways, and the dialogue was crisp with a few good lines. This type of pattern can give the show a longer life. • Another Great Episode While the main storyline and characters are interesting, I am finding myself preferring the others. I found this episode to be hilarious actually. The team are being interviewed by Miss Pickering from the state department to assess if they are a security threat. Probably not a good thing that I found it more entertaining than the rest of the episode. Angela treating Miss Pickering like a therapist, Zack's unwillingness to give away secrets without checking with Brennan first, Dr Goodman laughing at her, Hodgins taking offence at not being considered a threat and finally Brennan... well I won't spoil that one, but I found it incredibly amusing. It's so refreshing to have a show like this on the air. • Good episode. You got to see how uncomfortable Bones is in front of cameras and everyday conversations. Booth showed his softer side with the kidnapped child and the codeword. I didn't like that the episode never told you who was behind the kidnapping and murder. I loved how they said Zach was smarter than the computer guy.
dclm_baseline
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\section{Infinite Measure is Measure} Tags: Measures, Measure Theory \begin{theorem} Let $\struct {X, \Sigma}$ be a measurable space. Then the infinite measure $\mu$ on $\struct {X, \Sigma}$ is a measure. \end{theorem} \begin{proof} Let us verify the measure axioms $(1)$, $(2)$ and $(3')$ for $\mu$. \end{proof}
math_pile
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Kiss Mask Makes Smooching MandatoryS We're not sure what this art project from 1999 is designed to say, but it's a kissing mask that locks two girls into kissing mode when worn. During the exhibition, there was a microphone sewn into the connecting tube that recorded the "conversation, breathing and kissing that occurs inside," which was then burned onto CD as some kinda voyeuristic soundtrack. Weird, yet arousing. [JillMagid via Fleshbot]
dclm_baseline
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Tuning important Apache parameters. Although Apache performance can be improved by adding additional hardware resources such as more RAM, faster CPU, but most of the times, the real problem is that the webserver hasn't been configured properly and is not delivering optimal performance. Hence, the reason for this post is to get the important Apache parameters configured properly so as to get the maximum performance out of Apache with existing hardware resources
dclm_baseline
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microRNA-352 regulates collateral vessel growth induced by elevated fluid shear stress in the rat hind limb Received: 10 February 2017 Accepted: 20 June 2017 Published online: 27 July 2017 Yinglu Guan1,6, Baizhen Cai2, Xiaoqiong Wu3, Song Peng1,4, Liaoying Gan1, Da Huang1, Guangmin Liu1, Liping Dong1, Lin Xiao1, Junwen Liu1, Bin Zhang1, Wei-Jun Cai1, Jutta Schaper5 & Wolfgang Schaper5 Although collateral vessel growth is distinctly enhanced by elevated fluid shear stress (FSS), the underlying regulatory mechanism of this process remains incompletely understood. Recent studies have shown that microRNAs (miRNAs) play a pivotal role in vascular development, homeostasis and a variety of diseases. Therefore, this study was designed to identify miRNAs involved in elevated FSS- induced collateral vessel growth in rat hind limbs. A side-to-side arteriovenous (AV) shunt was created between the distal stump of one of the bilaterally occluded femoral arteries and the accompanying vein. The miRNA array profile showed 94 differentially expressed miRNAs in FSS-stressed collaterals including miRNA-352 which was down-regulated. Infusion of antagomir-352 increased the number and proliferation of collateral vessels and promoted collateral flow restoration in a model of rat hind limb ligation. In cell culture studies, the miR-352 inhibitor increased endothelial proliferation, migration and tube formation. In addition, antagomir-352 up-regulated the expression of insulin-like growth factor II receptor (IGF2R), which may play a part in the complex pathway leading to arterial growth. We conclude that enhanced collateral vessel growth is controlled by miRNAs, among which miR-352 is a novel candidate that negatively regulates arteriogenesis, meriting additional studies to unravel the pathways leading to improved collateral circulation. Under ischaemic conditions, collateral vessel growth or arteriogenesis (from pre-existing interconnecting arteri- oles to functional collateral arteries) is the body’s natural repair mechanism to restore blood flow to ischaemic tis- sues. The formation of functional collateral arteries can enhance the perfusion of ischaemic tissues approximately 10-fold1. Therefore, induction of arteriogenic reactions to enhance collateral vessel growth, also called therapeutic arteriogenesis has been suggested as a promising approach for the treatment of severe vascular occlusive disease1. In recent decades, dozens of arteriogenic factors, including FGFs, VEGF, PDGF and monocytes, have been stud- ied with varying success in various experimental models and in small open trials for the treatment of patients with coronary and periphery arterial diseases. www.nature.com/scientificreports www.nature.com/scientificreports www.nature.com/scientificreports Results iff Differential expression of miRNAs in collateral vessels and the miR-352 expression pat- tern. To investigate changes in the miRNA transcriptome induce by elevated FSS in collateral vessels, miRNA microarray analysis was performed with total RNA extracts of the isolated collateral vessels isolated from the superficial adductor muscles from both the ligature and AV-shunt sides (Figure S1 includes a graphic representa- tion of the AV-shunt). An increase in the number of collateral vessels was evident in the AV-shunt side compared to the ligature side (Fig. 1A). Among 3100 capture probes on the microarrays, 94 differentially expressed miRNAs (2-fold changes) were identified, among which 44 miRNAs were up-regulated and 50 were down-regulated; they are listed in the online-only Data Supplement (Figure S2 and Table S1).f Among those differentially expressed miRNAs (2-fold changes), many have been described to be involved in the regulation of cell proliferation, migration, MMPs, apoptosis, angiogenesis and growth factors (Tables 1 and 2), which are important factors that contribute to collateral vessel growth, indicating the validity of our experi- mental approach. On the other hand, of those differentially expressed miRNAs, a few have not previously been described or have been rarely reported, for example, miR-352. We screened potential miRNA seed sequences in the 3′-UTR using 3 bioinformatic algorithms (miRanda [www.microrna.org], miRDB [mirdb.org/miRDB] and targetscan [www.targetscan.org]), and identified 15 genes with a miR-352 target site predicted by all three bioin- formatic algorithms (Figure S4); one of them is IGF2R. IGF2R has angiogenic potency18, 19, and a previous study has demonstrated that IGF2R is up-regulated in collateral vessels in response to elevated FSS in a rabbit model8. Therefore, we speculated that miR-352 could regulate angiogenesis and arteriogenesis. To our knowledge, the only available information about the function of miR-352 was reported in Tao’s study, which showed that miR-352 is involved in the lysosomal-autophagy pathway20. Autophagy (“self-eating”) constitutes one of the most spectac- ular yet subtly regulated phenomena in cell biology. Because miR-352 has not been studied before in the context of collateral vessel growth, we selected it for further investigation. Quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) using miRNA stem loop primers for miR-352 was performed at one week after ligation or AV-shunt creation in 5 rats per group. www.nature.com/scientificreports/ via the pre-existent arterioles that now connect a high-pressure region with a low-pressure region3; this results in increased shear stress, which modulates many physiological, biochemical, and molecular responses in in vitro and in vivo experiments4–6. Indeed, we recently showed that elevated FSS achieved through an arteriovenous shunt (AV-shunt) created between the distal stump of an occluded femoral artery with the accompanying vein markedly amplifies collateral vessel growth7. Furthermore, increased expression of several biologically active substances, such as vascular endothelial cell adhesion molecules, inflammatory factors and growth factors was evident and several groups of differential mRNAs have been identified using this AV-shunt model8, 9. These data strongly suggest that increased FSS induced by arterial occlusion controls collateral vessel growth via regulating gene expression at both the protein and mRNA levels. p p microRNAs (miRNAs) are a novel class of regulatory noncoding, conserved, single-strand RNAs that nega- tively regulate over 30% of gene expression at the posttranscriptional level by binding to 3′ untranslated regions (3′-UTR) of target mRNAs10, 11. In the past few years, increasing evidence has documented an important regula- tory function of miRNAs in angiogenesis12–14. More recently, several studies have demonstrated that a different miRNA expression profile is induced in collateral vessels of mice following femoral artery occlusion, and sev- eral miRNAs such as miR-100, miR-155, miR-329 and miR-495 were found to be important factors that control collateral vessel growth15–17. These data highlight the importance of studies on the role of miRNA in regulating collateral vessel growth induced by FSS. Based on the above-mentioned findings and our previous findings that high levels of FSS lead to differential mRNA expression in collateral vessels between the AV-shunt side and the ligature-only side9, we hypothesized that there exists novel miRNAs that could play an important role in amplify- ing collateral vessel growth in response to elevated FSS.i g g p In the present study, we demonstrated a comprehensive miRNA expression profile in growing collateral vessels in the rat AV-shunt model. Next, we identified miR-352 as the most consistently down-regulated miRNA and investigated its localization in collateral vessels as well as its functions in collateral vessel growth. We determined that miR-352 is expressed in endothelial cells and inhibits arteriogenesis in vivo and angiogenesis in vitro via reg- ulating its target gene insulin-like growth factor II receptor/ cation-independent mannose 6-phosphate (IGF2R/ CI-M6P). microRNA-352 regulates collateral vessel growth induced by elevated fluid shear stress in the rat hind limb However, the data from two double-blinded, randomized, and placebo controlled clinical trials failed to provide evidence of its efficiency in the treatment of ischaemic patients2, indicating that a better understanding the molecular mechanisms of arteriogenesis and additional novel arterio- genic factors are required for the development of therapeutic arteriogenesis. g q p p g Fluid shear stress (FSS) has been acknowledged as a key trigger of collateral vessel growth. Once chronic occlusion or stenosis becomes significant, blood flow is directed towards the region with the lowest resistance 1Department of Histology & Embryology, School of Basic Medicine, Central South University Changsha, 410013, Hunan, P.R. China. 2Department of Intensive Care Unit, the 3rd Xiangya Hospital, Central South University Changsha, 410013, Hunan, P.R. China. 3Department of Anatomy & Neurobiology, School of Basic Medicine, Central South University Changsha, 410013, Hunan, P.R. China. 4Department of Radiology, the 3rd Xiangya Hospital, Central South University Changsha, 410078, Hunan, P.R. China. 5Max-Planck-Institute for Heart and Lung Research, Arteriogenesis Research Group, Bad Nauheim, D-61231, Germany. 6Department of Pharmacological & Pharmaceutical Sciences, College of Pharmacy, University of Houston, 77204, Houston, TX, United States. Correspondence and requests for materials should be addressed to B.Z. (email: coolzhangbin22@163.com) or W.-J.C. (email: caiweijun@csu.edu.cn or wjcai@yahoo.com) or J.S. (email: jutta.schaper@mpi-bn.mpg.de) SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 1 www.nature.com/scientificreports/ Results iff The results of the qRT-PCR experiment showed that miR-352 expression was constant in each sample and confirmed our microarray data, which showed that miR-352 was expressed in collateral vessels on ligation side and significantly decreased in shunt side (Fig. 1B). Using in situ hybridization and immunofluorescence for vascular markers, including a hybridization probe against U6 as a positive control, and a hybridization probe against miR-159 was used as a negative control (because this miRNA is not expressed in rat tissue), we found that miR-352 was mainly expressed in the endothelium and tunica media of collaterals and was significantly decreased in shunt-side collateral vessels (Fig. 1C). i In addition, to exclude possible contamination of muscle tissue in the transcriptome analysis, adductor mus- cles were harvested and used as positive controls for the RT-qPCR analysis of troponin I1 (Tnni1) and troponin I2 (Tnni2) in collateral vessels, since these two genes are specifically expressed in skeletal muscle. Expression of Tnni1 and Tnni2 was detected in the skeletal muscle but not in collaterals, where their Cq values were above 40 (Figure S3), indicating that there was no contamination by skeletal muscle in this study. miR-352 has anti-angiogenic potency in vitro. To investigate the potential role of miR-352 in angio- genesis, we used miR-352 mimic and inhibitor, respectively to overexpress and inhibit miR-352 in cultured rat aorta endothelial cells. CD31 antibody was used to verify the endothelial cells, showing a positive rate of >95%, and an optimized transfection protocol using a Cy3-conjugated mimic negative control resulted in a transfection efficiency of >90% in endothelial cells (Figure S5). qPCR showed that miR-352 expression was strongly increased SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 2 www.nature.com/scientificreports/ Figure 1. Expression of miR-352 in collateral vessels of the ligature-only side (LO) and the AV-shunt side (AVS). (A) Collateral vessels that were infused with liquid latex in the superficial adductor muscles from both the LO and AVS. An increased number of collaterals was evident in the AVS (indicated by arrows); original magnification: 10×. (B) Quantitative analysis of miR-352 expression by stem-loop qPCR in LO and AVS collateral vessels from each animal (***P < 0.001, n = 5). (C) In situ hybridization from miR-352 in collateral vessels of the LO and AVS. Green fluorescence and red fluorescence for CD31 and α-SM-actin, respectively. Results iff The U6 probe was used as a positive control, and miR-159 served as a negative control because this miRNA is not expressed in mammalian tissue. Notably, miR-352 was present mainly in endothelial and smooth muscle cells of the collateral vessels, and its expression was decreased in collateral vessels of the AVS as compared with those in the LO. Figure 1. Expression of miR-352 in collateral vessels of the ligature-only side (LO) and the AV-shunt side (AVS). (A) Collateral vessels that were infused with liquid latex in the superficial adductor muscles from both the LO and AVS. An increased number of collaterals was evident in the AVS (indicated by arrows); original magnification: 10×. (B) Quantitative analysis of miR-352 expression by stem-loop qPCR in LO and AVS collateral vessels from each animal (***P < 0.001, n = 5). (C) In situ hybridization from miR-352 in collateral vessels of the LO and AVS. Green fluorescence and red fluorescence for CD31 and α-SM-actin, respectively. The U6 probe was used as a positive control, and miR-159 served as a negative control because this miRNA is not expressed in mammalian tissue. Notably, miR-352 was present mainly in endothelial and smooth muscle cells of the collateral vessels, and its expression was decreased in collateral vessels of the AVS as compared with those in the LO. at 24 hours after transfection with miR-352 mimic, whereas transfection with miR-352 inhibitor resulted in a sig- nificant decrease in miR-352 expression (Figure S6). Transfection of the different compounds did not affect cell viability (Figure S7). A mimic and an inhibitor with irrelevant nucleotide sequences served as negative controls. The overexpression of miR-352 resulted in a decrease in endothelial cell network formation in the planar Matrigel (Fig. 2A), cell migration (Fig. 2B) and cell proliferation assays (Fig. 2C). In contrast, the inhibition of miR-352 resulted in an increase in endothelial cell network formation (Fig. 2A), cell migration (Fig. 2B) and cell prolif- eration (Fig. 2C). Taken together, we concluded that miR-352 has anti-angiogenic potency in endothelial cells. Inhibition of miR-352 by antagomir treatment promotes collateral vessels growth and collat- eral flow restoration in rat hind limbs. Based on the previous results, we tested whether inhibition of miR-352 promotes collateral vessel growth in vivo. miR-352 was modulated in vivo after femoral ligature by the additional application of antagomir-352 via osmotic mini pumps for a period of one week (Figure S8A). Results iff Given that miR-352 regulates angiogenesis and arteriogenesis, that all three bioinformatics algorithms predicted that IGF2R has a binding site for miR-352 and that IGF2R was up-regulated in collateral vessels by elevated FSS in a rabbit model8, we considered IGF2R to be an important potential target. IGF2R contains a miR-352 binding site in the 3′-UTR of its mRNA (Fig. 4A). To test whether miR-352 directly regulates IGF2R, we used a dual-luciferase reporter assay in RAECs transfected with either wild-type or mutated IGF2R 3′-UTR firefly luciferase constructs and miR-352 mimic or negative mimic control. Transfection of miR- 352 mimic inhibited luciferase activity, whereas mutant or mimic control had no effect (Fig. 4B), indicating that miR-352 can down-regulate IGF2R expression by binding to its 3′-UTR.l Furthermore, using qPCR, western blotting and immunofluorescence, we investigated the direct regulation of IGF2R by miR-352 in RAECs. Overexpression of miR-352 reduced IGF2R expression on both the mRNA and protein level in RAECs, whereas knockdown of miR-352 resulted in a significant up-regulation of IGF2R (Fig. 4C–E). These indicated that IGF2R is regulated by miR-352 in RAECs. gh g y To examine the biological relevance of reduced IGF2R by miR-352, we tested endothelial tube formation and cell proliferation in cultured RAECs treated with miR-353 inhibitor versus siIGF2R. qPCR showed that treatment with siIGF2R resulted in the suppression of IGF2R expression in RAECs (Figure S9). We found that treatment with miR-352 inhibitor + siIGF2R or Inhibitor cont + siIGF2R significantly reduced both endothelial tube forma- tion and cell proliferation in cultured RAECs compared to those in RAECs treated with miR-352 inhibitor + siNC or inhibitor + siNC (Fig. 5). Effect of FSS and antagomir-352 on the expression of IGF2R, IGF2, Beclin1, LC3a, LC3b and ATG5 during arteriogenesis. Because we found that miR-352 regulated IGF2R expression in vitro and because the literature showed that miR-352 is involved in the lysosomal-autophagy pathway, our next aim was to test whether inhibition of miR-352 altered the expression of IGF2R, IGF2, Beclin1, LC3a, LC3b and ATG5 in vivo. As expected, FSS or antagomir-352 treatment significantly increased both the mRNA and protein levels of IGF2R as compared to femoral ligature or antagomir control rats (Fig. 6A). Similar to IGF2R expression, increased expression of IGF2, a cognate ligand of IGF2R, was observed in either FSS or antagomir-352-treated rats (Fig. 6B). Results iff qPCR showed that antagomir-352 treatment resulted in a strong suppression of miR-352 expression in collateral vessels (Figure S8B). g To quantify arteriogenesis, the number of collateral vessels and proliferative cells in the vascular wall was determined by angiogram and Ki67 immunofluorescence staining, respectively. Analysis of the number of col- lateral vessels revealed a significant increase after one week of antagomir-352 treatment vs. antagomir control (Fig. 3A). In addition, Ki67 staining of collateral vessels revealed an increased proliferative activity of the vascular cells after miR-352 inhibition (Fig. 3B). It was noticed that although antagomir-352 treatment resulted in an increase in the number of collateral vessels and cell proliferation, these arteriogenic activities were still slightly less than those in shunt-treated animals (Fig. 3).tl Seven days after the initial operation and antagomir treatment, flow restoration in the simple femoral liga- tured hind limbs was 45.2 ± 5.0%, in the AV-shunted hind limbs was 93.1 ± 8.9%, in the femoral ligatured hind limbs treated with antagomir-352 was 89.6 ± 3.3%, and in the antagomir controls was 41.3 ± 6.4%, as com- pared with the non-occluded hind limbs (Fig. 3C). Analysis of flow restoration showed a significant increase after a week of antagomir-352 treatment vs. antagomir control (Fig. 3C). Histological studies of fluores- cence microsphere-perfused tissues showed that the number of fluorescence microspheres was higher in the antagomir-352-treated hind limbs than in the antagomir controls (Fig. 3C). SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 3 3 www.nature.com/scientificreports/ miRNA Fold change AV-shunt vs. control Function rno-miR-653-3p 37.56097561 Unknown rno-miR-3594-3p 9.31358885 Unknown rno-miR-483-3p 8.414634146 Anti-apoptotic oncogene, cardiovascular inflammation and remodelling rno-miR-92b-5p 8.096126255 Heart development and atrial fibrillation rno-miR-377-5p 4.84735544 Atrial fibrillation and structural remodelling rno-miR-341 4.764878049 Atrial fibrillation and TGF-β/Smad2/3 pathway rno-miR-21-3p 4.637785208 Cell proliferation and invasion. rno-miR-675-5p 4.143757751 Premature senescence of cardiac progenitor cells, G1 arrest, reduced cell proliferation, colony formation, migration and invasion rno-miR-183-3p 3.74730108 Regulates claudin-1 expression rno-miR-299a-5p 3.626723224 Anti-apoptotic role rno-miR-200c-3p 3.593610443 Targets the VEGF-VEGFR2 pathway and angiogenesis rno-miR-665 3.511737089 Negatively targets anti-apoptotic BCL2L1 rno-miR-291a-5p 3.457928187 VSMC migration rno-miR-490-5p 2.373358 Tumour suppressor rno-miR-1 2.505729 Suppresses cell growth rno-miR-133b 2.192279 Inhibits cell proliferation and invasion rno-miR-30c-1-3p 2.70761 Suppresses PXR expression rno-miR-294 2.010496 Promotes proliferation and differentiation rno-miR-127-5p 2.780488 A regulator of MMP-13 and suppresses cell growth rno-miR-503 2.327383 Inhibits cell proliferation and invasion Table 1. Twenty up-regulated miRNAs Table 1. Twenty up-regulated miRNAs. IGF2R is a target of miR-352. Results iff Expression of autophagic markers, Beclin1, LC3a, LC3b and ATG5 was significantly increased in the collateral vessels of shunt or antagomir-352-treated rats (Figs 6C and S10). g g To verify whether IGF2R is involved in regulating the autophagic activity induced by miR-352 inhibition, the ratio of LC3II to LC3I was measured in RACEs treated with miR-352 mimic, miR-352 inhibitor, siIGF2R or miR-352 inhibitor plus siIGF2R. We found that inhibition of miR-352 increased the LC3II/LC3I ratio, whereas miR-352 mimic reduced the LC3II/LC3I ratio (Figure S11). On the other hand, we found that the ratio of LC3II to LC3I was significantly lower in the RACEs treated with miR-352 inhibitor plus siIGF2R, as compared to those treated with miR-352 inhibitor (Figure S11), indicating that the miR-352-IGF2R pathway may regulate autophagy during collateral vessel growth. www.nature.com/scientificreports/ Here, we revealed that miRNAs control this amplified collateral vessel growth by mediating gene expression, showing that there exists a differential miRNA expression profile of a total of 94 differentially expressed miRNAs with 44 up-regulated and 50 down-regulated miRNAs compared to the ligature-only side of the collaterals. Furthermore, among these miRNAs, many were found to be involved in angiogenesis, including several with a regulatory function in cell proliferation, the expres- sion of growth factors and extracellular proteolysis, such as miR-497, miR-98, miR-181a, miR-145, miR-29b and miR-27a24–29. This is in agreement with our previous reports, which showed that these arteriogenic events are sig- nificantly augmented in the AV-side collateral vessels7, 30, implying that these miRNAs are likely novel candidates that regulate elevated FSS-induced collateral vessel growth. g g In the miRNA expression profile, we found several miRNAs including miR-352, that have not been previously described as regulators in vascular biology. miR-352 was first found in E18 rat primary cortical neurons31. It is closely related to let-7d-5p (BLAST, blast.ncbi.nlm.nih.gov), which is also down-regulated by FSS, but does not share the same seed sequence. To determine whether miR-352 is a novel candidate that regulates collateral vessel growth, we used 3 bioinformatic algorithms (miRanda [www.microrna.org], miRDB [mirdb.org/miRDB] and targetscan [www.targetscan.org]) to screen potential miRNA seed sequences in the 3′-UTR and identified IGF2R, which has a potential miR-352 target site that was predicted by all bioinformatic algorithms. IGF2R, a multiple ligand-binding cell transmembrane glycoprotein that is ubiquitously expressed in mammal tissues, plays a fun- damental role in regulation of autophagy, apoptosis and mitogenic effects32, 33. Moreover, our group previously demonstrated that IGF2R is up-regulated in collaterals by FSS in the rabbit model9. Its function in collateral vessel growth has not yet been investigated. All the above-mentioned findings indicate that miR-352 could be a novel miRNA regulator of elecated FSS-induced-collateral vessel growth. Indeed, this hypothesis was confirmed by the present study. We first used the in situ-hybridization approach to localize the cells that express miR-352 in collaterals and found that both, endothelial and smooth muscle cells express miR-352. Subsequently, we inves- tigated the role of miR-352 in angiogenesis in vitro by modulating miR-352 levels with both, loss-of-function and gain-of-function approaches using cultured rat endothelial cells. We chose endothelial cells for the in vitro experiment since the endothelium is directly exposed to FSS and plays an important role in arteriogenesis1. www.nature.com/scientificreports/ www.nature.com/scientificreports/ miRNA Fold change AV-shunt vs. control Function rno-let-7f-5p −5.200726271 Proangiogenesis and pulmonary arterial hypertension rno-miR-98-5p −4.790951973 Inhibits angiogenesis and regulates MMP-11 rno-miR-100-5p −4.56496786 Neovascularization rno-miR-30a −2.712938546 Inhibits the proliferation and migration of endothelial cells, promotes apoptosis and reduces autophagy activity rno-let-7a-5p −3.643793535 Inhibits endothelial and vascular smooth muscle cell proliferation rno-miR-26a-5p −3.478532104 Suppresses angiogenesis rno-miR-99a-5p −3.150019751 Suppresses proliferation and migration rno-miR-497-5p −2.888349061 Anti-angiogenesis and negatively regulates MMP-9 and VEGFA rno-miR-352 −2.873047456 Regulates lysosomal-associated membrane protein 2 rno-let-7d-5p −2.854490731 Vascular smooth muscle cell proliferation rno-miR-29b-3p −2.78013317 Atypical coronary artery disease, abdominal aortic aneurysm suppresses angiogenesis and regulates MMP-2 and VEGF rno-miR-30c-5p −2.774625087 Angiogenesis, vascular smooth muscle cell calcification, regulates angiogenesis and autophagy rno-let-7c-5p −2.738042055 let-7 family and inhibits proliferation and migration rno-miR-145-5p −2.209690820 Inhibits angiogenesis rno-miR-27b −2.373222456 Inhibits angiogenesis and regulates VEGF-C and MMP-13 rno-let-7b −2.14686718 Promotes angiogenesis and suppresses apoptosis and autophagy rno-miR-30e −2.15284326 Induces apoptosis and regulates SMC proliferation and differentiation rno-miR-10a-5p −2.36103536 Pro-angiogenic activity and regulates VEGF and VE-cadherin rno-miR-181a −2.1600044 Inhibits angiogenesis and regulates MMP-14 rno-miR-27a-3p −2.6992738 Regulates VE-cadherin, cell proliferation, apoptosis and MMP13 Table 2. Twenty down-regulated miRNAs. Table 2. Twenty down-regulated miRNAs. role in FSS-induced collateral vessel growth; (3) miR-352 regulates autophagy through regulating its target gene IGF2R/CI-M6P during arteriogenesis in a rat AV-shunt model.ht ole in FSS-induced collateral vessel growth; (3) miR-352 regulates autophagy through regulating its target gene GF2R/CI-M6P during arteriogenesis in a rat AV-shunt model.ht g g The restoration of maximal conductance through the body’s natural repair mechanism in animals after arterial occlusion only reaches 35% to 40% of normal21, 22. However, high levels of FSS generated by shunting most of the collateral flow directly into the accompanying venous system could normalize the maximal conductance7, 8. In this AV-shunt model, the growth of collateral vessels was dramatically enhanced, not only in size but also in num- ber, as compared with that in the ligature-only side7, 8. We previously demonstrated that several molecules, such as TRPV4 and ABRA, play an important role in this high FSS induced arteriogenic response9, 23 and identified several groups of differentially expressed mRNAs in this AV-shunt model9, implying that altered gene expres- sion is involved in this rapid and amplified collateral vessel growth. Discussionhi The main findings of this study areas follows: (1) a different miRNA expression profile exists in collateral ve nduced by elevated FSS in the rat AV-shunt model; (2) miR-352 is down-regulated and has an anti-arteriog SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 4 www.nature.com/scientificreports/ Ligature: the ligature-only side; Shunt: the AV shunt side; antagomir-352: rats infused with antagomirs targeting miR-352 through an osmotic mini pump connected to the proximal region of the occluded femoral artery; and antagomir-cont: control antagomir. (A) Postmortem angiograms of rat hind limbs on day 7 after infusion. Antagomir-352 treatment resulted in an increase in the number of collateral vessels (arrows) as compared to antagomir-cont treatment. This increase is similar to the number of collateral vessels observed following shunt treatment. (***P < 0.001, **P < 0.01, n = 5). (B) Cell proliferation was detected by Ki67 immunostaining in collateral vessels from different groups. Green fluorescence for Ki67, red for F-actin, blue for nuclei. Notably, Ki67-positive cells were more numerous in collaterals treated with antagomir-352 than in the control side, which is similar to what is observed following shunt treatment (**P < 0.01, n = 5). (C) Flow ratio of rat hind limbs at day 7 after antagomir-352 infusion and fluorescence microspheres administration in adductor muscles. Antagomir-352 treatment resulted in a significant increase in collateral flow, compared to antagomir-cont treatment. This increase is similar to that observed following shunt treatment (**P < 0.01, ***P < 0.001, n = 5). Red fluorescence for the fluorescence microspheres, and green for F-actin. The number of fluorescence microspheres was higher in the antagomir-352-treated and AV shunt-side muscles. Figure 3. Inhibition of miR-352 enhances arteriogenesis and promotes flow restoration in rat hind limbs. Ligature: the ligature-only side; Shunt: the AV shunt side; antagomir-352: rats infused with antagomirs targeting miR-352 through an osmotic mini pump connected to the proximal region of the occluded femoral artery; and antagomir-cont: control antagomir. (A) Postmortem angiograms of rat hind limbs on day 7 after infusion. Antagomir-352 treatment resulted in an increase in the number of collateral vessels (arrows) as compared to antagomir-cont treatment. This increase is similar to the number of collateral vessels observed following shunt treatment. (***P < 0.001, **P < 0.01, n = 5). (B) Cell proliferation was detected by Ki67 immunostaining in collateral vessels from different groups. Green fluorescence for Ki67, red for F-actin, blue for nuclei. Notably, Ki67-positive cells were more numerous in collaterals treated with antagomir-352 than in the control side, which is similar to what is observed following shunt treatment (**P < 0.01, n = 5). (C) Flow ratio of rat hind limbs at day 7 after antagomir-352 infusion and fluorescence microspheres administration in adductor muscles. www.nature.com/scientificreports/ Inhibition of miR-352 enhances arteriogenesis and promotes flow restoration in rat hind limb Ligature: the ligature-only side; Shunt: the AV shunt side; antagomir-352: rats infused with antagomirs ta miR-352 through an osmotic mini pump connected to the proximal region of the occluded femoral arter and antagomir-cont: control antagomir. (A) Postmortem angiograms of rat hind limbs on day 7 after infu Antagomir-352 treatment resulted in an increase in the number of collateral vessels (arrows) as compare antagomir-cont treatment. This increase is similar to the number of collateral vessels observed following treatment. (***P < 0.001, **P < 0.01, n = 5). (B) Cell proliferation was detected by Ki67 immunostainin collateral vessels from different groups. Green fluorescence for Ki67, red for F-actin, blue for nuclei. Nota Ki67-positive cells were more numerous in collaterals treated with antagomir-352 than in the control sid which is similar to what is observed following shunt treatment (**P < 0.01, n = 5). (C) Flow ratio of rat h limbs at day 7 after antagomir-352 infusion and fluorescence microspheres administration in adductor m Antagomir-352 treatment resulted in a significant increase in collateral flow, compared to antagomir-con treatment. This increase is similar to that observed following shunt treatment (**P < 0.01, ***P < 0.001, 5) R d fl f th fl i h d f F ti Th b f fl Figure 3. Inhibition of miR-352 enhances arteriogenesis and promotes flow restoration in rat hind limbs Ligature: the ligature-only side; Shunt: the AV shunt side; antagomir-352: rats infused with antagomirs tar miR-352 through an osmotic mini pump connected to the proximal region of the occluded femoral artery and antagomir-cont: control antagomir. (A) Postmortem angiograms of rat hind limbs on day 7 after infu Antagomir-352 treatment resulted in an increase in the number of collateral vessels (arrows) as compared antagomir-cont treatment. This increase is similar to the number of collateral vessels observed following s treatment. (***P < 0.001, **P < 0.01, n = 5). (B) Cell proliferation was detected by Ki67 immunostaining collateral vessels from different groups. Green fluorescence for Ki67, red for F-actin, blue for nuclei. Nota Ki67 positive cells were more numerous in collaterals treated with antagomir 352 than in the control side Figure 3. Inhibition of miR-352 enhances arteriogenesis and promotes flow restoration in rat hind limbs. www.nature.com/scientificreports/ We found that overexpression of miR-352 suppressed endothelial cell proliferation, migration and network forma- tion, whereas inhibition of miR-352 promoted endothelial network formation, cell migration and proliferation, suggesting an anti-angiogenic potency of miR-352. Furthermore, using the in vivo antagomir approach, we SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 5 www.nature.com/scientificreports/ Figure 2. Effect of miR-352 overexpression or inhibition on angiogenesis in cultured rat aorta endothelial (RAECs). RAECs were transfected with either miR-352 mimic, miR-352 inhibitor or the respective negativ controls: mimic control/inhibitor control. (A) Transfected cells were cultured on Matrigel, and the cumula sprout length and branch points of capillary-like structures were measured after 6 hours. miR-352 mimic attenuated angiogenic tube formation, whereas inhibition of miR-352 had a stimulatory effect. (***P < 0.0 n = 3). (B) Stained migratied transfected cells on the bottom side of the Transwell chamber after 24 hours. 352 mimic attenuated cell migration, whereas inhibition of miR-352 promoted cell migration. (***P < 0.0 n = 3). (C) Proliferation of transfected cells was examined by Ki67 immunostaining. Green for Ki67, and b for nuclei. miR-352 mimic attenuated cell proliferation, whereas miR-352 inhibitor promoted cell prolifera (*P < 0.05, n = 3). Figure 2. Effect of miR-352 overexpression or inhibition on angiogenesis in cultured rat aorta endothelial cells (RAECs). RAECs were transfected with either miR-352 mimic, miR-352 inhibitor or the respective negative controls: mimic control/inhibitor control. (A) Transfected cells were cultured on Matrigel, and the cumulative sprout length and branch points of capillary-like structures were measured after 6 hours. miR-352 mimic attenuated angiogenic tube formation, whereas inhibition of miR-352 had a stimulatory effect. (***P < 0.001, n = 3). (B) Stained migratied transfected cells on the bottom side of the Transwell chamber after 24 hours. miR- 352 mimic attenuated cell migration, whereas inhibition of miR-352 promoted cell migration. (***P < 0.001, n = 3). (C) Proliferation of transfected cells was examined by Ki67 immunostaining. Green for Ki67, and blue for nuclei. miR-352 mimic attenuated cell proliferation, whereas miR-352 inhibitor promoted cell proliferation (*P < 0.05, n = 3). 6 SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 www.nature.com/scientificreports/ www.nature.com/scientificreports/ www.nature.com/scientificreports/ ntificreports/ Figure 3. www.nature.com/scientificreports/ Antagomir-352 treatment resulted in a significant increase in collateral flow, compared to antagomir-cont treatment. This increase is similar to that observed following shunt treatment (**P < 0.01, ***P < 0.001, n = 5). Red fluorescence for the fluorescence microspheres, and green for F-actin. The number of fluorescence microspheres was higher in the antagomir-352-treated and AV shunt-side muscles. 7 SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 www.nature.com/scientificreports/ Figure 4. Identification of IGF2R as a target of miR-352 in rat aorta endothelial cells (RAECs). (A) Seed sequence of miR-352, and the complementary 3′-UTR sequence of IGF2R. (B) Luciferase analysis. Luciferase activity of the IGF2R wt 3′-UTR construct but not the IGF2R mut construct, was decreased in the miR-352- expressing cells (*P < 0.05, n = 3). (C–E) Overexpression or inhibition of miR-352 in RAECs resulted in a decrease or an increase in IGF2R expression on both the mRNA (C) and protein (D,E) levels as determined by qPCR (C), western blot (D) and immunofluorescence staining (E), respectively. Specific fluorescence in green, and nuclei staining in blue (***P < 0.001, *P < 0.05, n = 3). Figure 4. Identification of IGF2R as a target of miR-352 in rat aorta endothelial cells (RAECs). (A) Seed sequence of miR-352, and the complementary 3′-UTR sequence of IGF2R. (B) Luciferase analysis. Luciferase activity of the IGF2R wt 3′-UTR construct but not the IGF2R mut construct, was decreased in the miR-352- expressing cells (*P < 0.05, n = 3). (C–E) Overexpression or inhibition of miR-352 in RAECs resulted in a decrease or an increase in IGF2R expression on both the mRNA (C) and protein (D,E) levels as determined by qPCR (C), western blot (D) and immunofluorescence staining (E), respectively. Specific fluorescence in green, and nuclei staining in blue (***P < 0.001, *P < 0.05, n = 3). demonstrated that inhibition of miR-352 promotes cell proliferation, collateral vessel growth and collateral flow restoration after femoral ligature in the rat hind limb. These data lead to the conclusion that miR-352 is not only an anti-angiogenic regulator but also an anti-arteriogenic regulator. g g g g g Analysis using 3 bioinformatic algorithms predicted that IGF2R is the target of miR-352. Indeed, we found that in AV-shunt collaterals down-regulation of miR-352 expression was accompanied by increased IGF2R expression. Moreover, an increase in IGF2R expression in collaterals was evident after miR-352 gene silencing. www.nature.com/scientificreports/ Furthermore, our in vitro experiments demonstrate that inhibition or overexpression of miR-352 results in the up-regulation or down-regulation of IGF2R expression in endothelial cells respectively. These findings confirm that IGF2R is negatively regulated by miR-352. In addition, we showed that knockdown of IGF2R suppresses cell proliferation and endothelial network formation in vitro, indicating that IGF2R plays an important role in cell proliferation and angiogenesis. This is in line with two previous reports that showed that IGF2R is required for angiogenesis18, 19. The function of IGF2R is initiated by binding to its cognate ligand IGF2, a protein hormone known to regulate cell proliferation, growth, migration, differentiation and survival34. We observed that increased expression of IGF2R was accompanied by up-regulation of IGF2 in AV-shunt side collateral vessels, suggesting that the IGF2-IGF2R pathway was involved. Taken together, these data demonstrate that the miR-352-IGF2R pathway is involved in angiogenesis and arteriogenesis. p y g g g In addition to its angiogenic potency, IGF2R is known to regulate autophagy, apoptosis and cell survival33, 35. Most recently, Tao et al. showed that miR-352 regulates autophagy following ischaemic stroke20. In the present study SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 8 www.nature.com/scientificreports/ www.nature.com/scientificreports/ Figure 5. miR-352 regulates endothelial tube formation and cell proliferation in cultured RAECs by targeting the IGF2R gene. (A) Effect of miR-352 inhibitor + siIGF2R (IGF2R siRNA); miR-352 inhibitor + siNC (a scrambled siRNA); siIGF2R + inhibitor cont; or siNC + inhibitor cont on endothelial tube formation (***P < 0.001, n = 3). (B) Effect of the miR-352 inhibitor + siIGF2R (IGF2R siRNA); miR-352 inhibitor + siNC (a scrambled siRNA); siIGF2R + inhibitor cont or siNC + inhibitor cont on RAEC proliferation was detected by Ki67 immunofluorescence. Specific fluorescence in green, and nuclei are labelled in blue. Notably, treatment with miR- 352 inhibitor + siIGF2R or inhibitor cont + siIGF2R significantly reduced both endothelial tube formation and cell proliferation in cultured RAECs as compared to treatment with miR-352 inhibitor + siNC or inhibitor + siNC, respectively, indicating that IGF2R is a miR-352 target in RAECs (***P < 0.001, *P < 0.05, n = 3). Figure 5. miR-352 regulates endothelial tube formation and cell proliferation in cultured RAECs by targeting the IGF2R gene. www.nature.com/scientificreports/ (A) Effect of miR-352 inhibitor + siIGF2R (IGF2R siRNA); miR-352 inhibitor + siNC (a scrambled siRNA); siIGF2R + inhibitor cont; or siNC + inhibitor cont on endothelial tube formation (***P < 0.001, n = 3). (B) Effect of the miR-352 inhibitor + siIGF2R (IGF2R siRNA); miR-352 inhibitor + siNC (a scrambled siRNA); siIGF2R + inhibitor cont or siNC + inhibitor cont on RAEC proliferation was detected by Ki67 immunofluorescence. Specific fluorescence in green, and nuclei are labelled in blue. Notably, treatment with miR- 352 inhibitor + siIGF2R or inhibitor cont + siIGF2R significantly reduced both endothelial tube formation and cell proliferation in cultured RAECs as compared to treatment with miR-352 inhibitor + siNC or inhibitor + siNC, respectively, indicating that IGF2R is a miR-352 target in RAECs (***P < 0.001, *P < 0.05, n = 3). using Beclin1 and LC3 as markers of autophagy, we found that inhibition of IGF2R in cultured RAECs resulted in a decrease in autophagic activity. On the other hand, inhibition of miR-352 in vivo led to an up-regulation of IGF2R expression and increased autophagic activity in collaterals, which was indicated by increased expression of several autophagy-related genes, including Beclin1, ATG5 and LC3. Therefore, we propose that miR-352 regulates autophagy during collateral vessel growth by targeting IGF2R expression. Autophagy is a catabolic process that is important for protein degradation, organelle turnover and the recycling of cytoplasmic components, which allow cells to adapt to changing nutritional and energy demands by repurposing existing cellular components to sustain cellular metabolism, homeostasis, and survival36. Although the role of autophagy in the cardiovascular system is somehow controversial37, our data support the notion that increased autophagy facilitates collateral vessel growth. On one hand, endothelial cells activated by elevated FSS contain numerous cellular organelles; in particular, there are large numbers of free ribosomes in the cytoplasm38–40. They also exhibit increased expression of endothelial NO syn- thetase (eNOS), monocyte chemoattractant protein (MCP-1) and the adhesion molecules ICAM-1 and VCAM1, 6, 40. SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 9 www.nature.com/scientificreports/ re.com/scientificreports/ Figure 6. Effect of FSS and antagomir-352 on the expression of IGF2R, IGF2 and Beclin1 in collateral vessels of rat hind limbs. (A) IGF2R immunostaining and qPCR. (B) IGF2 immunostaining and qPCR. (C) Beclin1 immunostaining and qPCR. Specific fluorescence in green; red fluorescence for CD31 in A and for α-SM-actin in (B and C) blue fluorescence labels nuclei. www.nature.com/scientificreports/ Ligature: ligature-only side; Shunt: AV-shunt side; antagomir-352: antagomir-352 treated-side; antagomir-cont: antagomir-352 control. Both shunting and antagomir-352 treatment up-regulated expression of IGF2R, IGF2 and Beclin1 (***P < 0.001, **P < 0.01, *P < 0.05, n = 5). Figure 6. Effect of FSS and antagomir-352 on the expression of IGF2R, IGF2 and Beclin1 in collateral vessels of rat hind limbs. (A) IGF2R immunostaining and qPCR. (B) IGF2 immunostaining and qPCR. (C) Beclin1 immunostaining and qPCR. Specific fluorescence in green; red fluorescence for CD31 in A and for α-SM-actin in (B and C) blue fluorescence labels nuclei. Ligature: ligature-only side; Shunt: AV-shunt side; antagomir-352: antagomir-352 treated-side; antagomir-cont: antagomir-352 control. Both shunting and antagomir-352 treatment up-regulated expression of IGF2R, IGF2 and Beclin1 (***P < 0.001, **P < 0.01, *P < 0.05, n = 5). On the other hand, when endothelial cell autophagy was impaired by Atg3 siRNA or the autophagy inhibitor 3-MA, FSS was incapable of increasing eNOS expression, phosphorylation and NO production41, 42. Furthermore, Du et al. showed that induction of autophagy promotes angiogenesis while inhibition of autophagy suppresses angiogenesis43. It should be noted that the miR-352-IGF2R pathway may not be the only mechanism for regulating autophagy dur- ing collateral vessel growth because additional miRNAs involved in autophagy were identified, such as, miR-30. Pan et al. reported that miR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy44, which implies that there exists a complicated network for mediating autophagy that has yet to be determined. l h d d h d ff l f h b On the other hand, when endothelial cell autophagy was impaired by Atg3 siRNA or the autophagy inhibitor 3-MA, FSS was incapable of increasing eNOS expression, phosphorylation and NO production41, 42. Furthermore, Du et al. showed that induction of autophagy promotes angiogenesis while inhibition of autophagy suppresses angiogenesis43. It should be noted that the miR-352-IGF2R pathway may not be the only mechanism for regulating autophagy dur- ing collateral vessel growth because additional miRNAs involved in autophagy were identified, such as, miR-30. Pan et al. reported that miR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy44, which implies that there exists a complicated network for mediating autophagy that has yet to be determined.f In conclusion, we have demonstrated that differential expression of numerous miRNAs might be an important mechanism for rapid and augmented collateral vessel growth in the AV-shunt model. Materials and Methods i l d lh Animal model. The experimental protocol was approved by the Animal Care and Use Committee of Central South University and adhered to the Guidance Suggestions for the Care and Use of Laboratory Animals by the Ministry of Science and Technology of the People’s Republic of China. Adult Sprague-Dawley (SD) rats (250– 300 g, Animal Center, Xiangya School of Medicine, Central South University, Changsha, China) were anaesthe- tized with chloral hydrate (300 mg/kg, intraperitoneally). Bilateral femoral artery occlusion was performed in animals by ligating the femoral artery. On the left side, an arterio-venous (AV) fistula was created side-to-side between the distal femoral artery stump and the accompanying femoral vein, and the right side was used as a control8. Then, the skin was closed with sterile surgical clips. The animals were allowed to recover completely and were housed with free access to water and food. Gangrene and gross impairment of hind limb function were not observed in any of the rats. A total of 15 SD rats were used for the AV model. Tissue preparation. For immunofluorescence staining, the animals were killed under anaesthesia one week after the operation. Quadricep and adductor muscles were carefully removed for the experiments. Base on our previous experience, these muscles contain one or two collateral vessels during arteriogenesis. A total of 36 ves- sels were investigated. All samples were immediately frozen in liquid nitrogen, embedded in tissue processing medium (Tissue-Tek O.C.T, Sakura, CA, USA), and stored at −80 °C until further analysis. ( ) y To isolate collateral arteries, the hind limb vasculature was visualized with liquid latex as previously described45. Animals were anaesthetized, the aorta was cannulated, and the animals were exsanguinated then warm (37 °C) liquid latex (THAI HUA TEX, Thailand) was infused at a pressure of 80 mmHg. Collateral arteries bypassing the site of the operation were carefully dissected from the quadricep and adductor muscles after the hardening of the latex under a stereomicroscope and snap frozen in liquid nitrogen until RNA isolation. In addi- tion, adductor muscles were harvested and used as positive controls for RT-qPCR analysis of troponin I1 (Tnni1) and troponin I2 (Tnni2) expression. miRNA microarray analysis. Total small RNA was isolated from collateral arteries in the quadricep and adductor muscles from 5 rats using the by mirVanatm miRNA Isolation Kit (Ambion, Life Technologies, CA, USA) at one week after the operation. Materials and Methods i l d lh A portion of RNA from each sample was pooled in equal amounts, and microarray analysis for all identified rat miRNAs (miRBase 16.0) was performed by the Exiqon miRNA Expression Profiling service (Kangchen Bio-tech, China). The other portion of RNA in each sample was used for further qPCR analysis of miRNA expression. In vivo antagomir. Following the occlusion, 5 SD rats underwent intra-arterial injection of 500 nmol/kg antagomir (Ribobio, China) via subcutaneously implanted osmotic mini pumps (Model 1007, Alzet® Osmotic Pumps, CA, USA) connected to a catheter. The catheter was inserted retrograde into the proximal region of the occluded femoral artery. An antagomir-control was used as a negative control. Postmortem angiograms. Postmortem angiography was performed by injecting the contrast medium as previously described22. Gelatine (20 g, type A, Sigma, MO, USA) was dissolved in 100 ml of 50 °C distilled water with continuous steering. Afterward, 100 g of lead oxide (Sigma, MO, USA) was added and mixed well. Animals were anaesthesized and anticoagulated, and the aorta was cannulated. Subsequently, the animals were bled and immersed in water warmed to 50 °C. Then, the contrast medium was infused at a pressure of 150–180 mmHg until filling of the distal femoral stump was observed. The animals were immediately placed on crushed ice, and the contrast medium was allowed to harden under continuous pressure. X-ray images were taken in an X-ray chamber (model DHF-155H, Tokyo Japan, HITACHI MEDICAL CORPORATION) exposed to 50 KV and 100 mA for 30 mS. Images were acquired and transferred to a computer, which was used to identify and quantify the collateral arteries. Collateral flow measurements. Collateral flow measurements were performed as previously described46, 47. Briefly, at 7 days after the initial operation and antagomir treatment, the animals were anaesthetized with chloral hydrate (300 mg/kg, intraperitoneally). A catheter was inserted in the abdominal aorta with the tip just proximal to the aortic bifurcation. Both hind limbs were perfused at 3 different pressures (60, 80 and 100 mm Hg) with heparinized saline and adenosine (1.0 mg/kg per min, Sigma, MO, USA) to achieve maximal vasodilatation. At each pressure level, 3 × 106 red microspheres of 15 μm in diameter (Molecular Probes, OR, USA) were thoroughly mixed and injected into the perfusion system. www.nature.com/scientificreports/ We identified that miR- 352 is a novel candidate that negatively regulates collateral vessel growth and demonstrated that miR-352 is an endogenous IGF2R modulator in the regulation of angiogenesis and autophagy. However, it should be noted that although miRNAs-including miR-352 in this paper and other miRNAs found in previous studies, such as miR- 100, miR-155, miR-329, and miR-495- are important factors controlling FSS-induced collateral vessel growth15–17, SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 10 www.nature.com/scientificreports/ the mechanism by which miRNAs expression is regulated remains unclear. Currently there is no evidence regard- ing the interaction between FSS and the expression of those miRNAs, therefore, further elucidation of how miR- NAs are regulated is needed and may lead to clinical applications of miRNAs as therapeutic tools. the mechanism by which miRNAs expression is regulated remains unclear. Currently there is no evidence regard- ing the interaction between FSS and the expression of those miRNAs, therefore, further elucidation of how miR- NAs are regulated is needed and may lead to clinical applications of miRNAs as therapeutic tools. www.nature.com/scientificreports/ Statistical analysis. All data were presented as the mean ± SEM using Prism 5 (GraphPad Software Inc, CA, USA). Treatment groups were compared by unpaired Student’s t-test, and one-way ANOVA was used for multiple comparisons of >2 groups. A P value < 0.05 was considered statistically significant. Statistical analysis. All data were presented as the mean ± SEM using Prism 5 (GraphPad Software Inc, CA, USA). Treatment groups were compared by unpaired Student’s t-test, and one-way ANOVA was used for multiple comparisons of >2 groups. A P value < 0.05 was considered statistically significant. References p y gy p 5. Siragam, V. et al. 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Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coro collateral development and the arterial response to injury. Circulation 94, 1074–1082 (1996).t 2. Ito, W. D. et al. Monocyte chemotactic protein-1 increases collateral and peripheral conductance after femoral artery occlusion Circulation research 80, 829–837 (1997). 23. Troidl, C. et al. Trpv4 induces collateral vessel growth during regeneration of the arterial circulation. Journal of cellular and molecular medicine 13, 2613–2621 (2009). 24. Wang, W. et al. MicroRNA-497 suppresses angiogenesis by targeting vascular endothelial growth factor A through the PI3K/AKT and MAPK/ERK pathways in ovarian cancer. Oncology reports 32, 2127–2133 (2014). Materials and Methods i l d lh At the distal end of the perfusion system, a reference blood sample was withdrawn for one minute at a rate of 0.4 mL/min after the onset of microsphere injection.t t After the microsphere injection, the animals were euthanized, and their hind limb muscles (i.e., quadricep and adductor muscles) were dissected. Tissue was digested and homogenized with SDS/proteinase solution for FACS analysis and microsphere quantification. Restoration of flow was then expressed as a percentage derived from the ratio between the flows in the experimental hind limb versus that in the non-occluded hind limb.l l In addition, histological studies of the tissues perfused with fluorescence microspheres were performed. Quadricep and adductor muscles were carefully removed under anaesthesia after microsphere injection and embedded in tissue processing medium. Cryosections 20 μm thick were obtained and fixed in 4% paraformal- dehyde. Then sections were incubated with Actin-Phalloidin (FITC labelled), cover-slipped and viewed with a Nikon confocal microscope (Nikon, Japan). SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 11 www.nature.com/scientificreports/ References References 1. Cai, W. & Schaper, W. Mechanisms of arteriogenesis. Acta biochimica et biophysica Sinica 40, 681–692 (2008). , p , g p y , ( ) 2. de Muinck, E. D. & Simons, M. Re-evaluating therapeutic neovascularization. Journal of molecular and cellular cardiology 36, 25–32 (2004). (2004). 3. Schaper, W. & Pasyk, S. Influence of collateral flow on the ischemic tolerance of the heart following acute and subacute coronary occlusion. Circulation 53, I57–62 (1976). 4. Shyy, Y. J., Hsieh, H. J., Usami, S. & Chien, S. Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America 91, 4678–4682 (1994). ( ) 5. Mitsumata, M., Fishel, R. S., Nerem, R. M., Alexander, R. W. & Berk, B. C. Fluid shear stress stimulates platelet-derived growth facto expression in endothelial cells. The American journal of physiology 265, H3–8 (1993). h 6. Cai, W. J., Kocsis, E., Luo, X., Schaper, W. & Schaper, J. Expression of endothelial nitric oxide synthase in the vascular wall during arteriogenesis. Molecular and cellular biochemistry 264, 193–200 (2004). arteriogenesis. Molecular and cellular biochemistry 264, 193–200 (2l g y 7. Pipp, F. et al. Elevated fluid shear stress enhances postocclusive collateral artery growth and gene expression in the pig hind limb Arteriosclerosis, thrombosis, and vascular biology 24, 1664–1668 (2004).ht gy 8. Eitenmuller, I. et al. The range of adaptation by collateral vessels after femoral artery occlusion. Circulation research 99, 656–662 (2006). 9. Troidl, K. et al. Actin-binding rho activating protein (Abra) is essential for fluid shear stress-induced arteriogenesis. Arteriosclerosis thrombosis, and vascular biology 29, 2093–2101 (2009).h gy 10. Ambros, V. The functions of animal microRNAs. Nature 431, 350–355 (2004). gy 0. Ambros, V. The functions of animal microRNAs. Nature 431, 350–355 (2004). h 11. Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281–297 (2004). 12. Hans, F. P., Moser, M., Bode, C. & Grundmann, S. MicroRNA regulation of angiogenesis and arteriogenesis. Trends in cardiovas medicine 20, 253–262 (2010). 13. Bonauer, A. et al. MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 324, 1710– (2009). 14. Liu, C. H. et al. Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization. Proceedings o National Academy of Sciences of the United States of America 112, 12163–12168 (2015). y f f f rundmann, S. Acknowledgements This work was supported by a grant from the National Natural Science Foundation of China (no: 81370248). Acknowledgements This work was supported by a grant from the National Natural Science Foundation of China (no: 81370248). g This work was supported by a grant from the National Natural Science Foundation of China (no: 81370248). References Ultrastructure of ischemia-induced changes in the precapillary anastomotic network of the heart. The American journal of cardiology 29, 851–859 (1972).h h 39. Schaper, J., Konig, R., Franz, D. & Schaper, W. The endothelial surface of growing coronary collateral arteries. Intimal margination and diapedesis of monocytes. A combined SEM and TEM study. Virchows Archiv. A, Pathological anatomy and histology 370, 193–205 (1976). SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 12 www.nature.com/scientificreports/ 40. Scholz, D. et al. Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis). Virc Archiv: an international journal of pathology 436, 257–270 (2000). j f p gy 41. Bharath, L. P. et al. Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric o bioavailability. Canadian journal of physiology and pharmacology 92, 605–612 (2014). y j f p y gy p gy 2. Guo, F. et al. Autophagy regulates vascular endothelial cell eNOS and ET-1 expression induced by laminar shear stress in an ex vivo perfused system. Annals of biomedical engineering 42, 1978–1988 (2014). Guo, F. et al. Autophagy regulates vascular endothelial cell eNOS an p y f g g ( ) 3. Du, J. et al. Role of autophagy in angiogenesis in aortic endothelial cells. American journal of physiology. Cell physiology 302 C383–391 (2012). 44. Pan, W. et al. MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy. PloS one 8, e53950 (2013). 44. Pan, W. et al. MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy. PloS one 8, e53950 (2013 45. Grundmann, S. et al. Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adh in arteriogenesis. Journal of cellular and molecular medicine 13, 3463–3474 (2009). 46. Hoefer, I. E., van Royen, N., Buschmann, I. R., Piek, J. J. & Schaper, W. Time course of arteriogenesis following femoral artery occlusion in the rabbit. Cardiovascular research 49, 609–617 (2001). 46. Hoefer, I. E., van Royen, N., Buschmann, I. R., Piek, J. J. & Schaper, W. Time course of arteriogenesis following femoral artery occlusion in the rabbit. Cardiovascular research 49, 609–617 (2001). ( ) 47. Hoefer, I. E. et al. Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis. Circulation 105, 1639–1641 (2002). Acknowledgements 47. Hoefer, I. E. et al. Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis. Circulation 105, 1639–1641 (200 A k l d t Author Contributions W.C. and Y.G. designed the study. Y.G., B.C., L.G., D.H., G.L. and L.D. performed the in vitro and in vivo experiments, collated the data, designed and developed the database, and carried out data analyses. X.W., S.P., L.X., J.L., B.Z. contributed to the data analysis. Y.G. and W.C. prepared the figures, tables and produced the initial draft of the manuscript. W.C. and J.S. revised the paper. W.C. and W.S. contributed reagents. SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 Additional Information Supplementary information accompanies this paper at doi:10.1038/s41598-017-06910-9 Supplementary information accompanies this paper at doi:10.1038/s41598-017-06910-9 Competing Interests: The authors declare that they have no competing interests. Competing Interests: The authors declare that they have no competing interests. Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps an institutional affiliations. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Cre- ative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not per- mitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2017 SCIeNtIfIC REPOrts | 7: 6643 | DOI:10.1038/s41598-017-06910-9 13
common_corpus
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The 10 Python Conferences Happening at PyCon 2011 (part 3) This is the third in a series of posts about the schedule for PyCon 2011. In designing this schedule, we found that there are actually 10 different conferences happening in parallel at PyCon. The first post introduced the series and discussed the Django virtual track. The second post focused on the web working virtual track. This post focuses on the third virtual track, Python and NoSQL. Python and NoSQL One of the more interesting developments in the past couple years is the use of NoSQL databases. FOr many years, the default answer to any kind of persistence problem was simply to put it in a (relational) database. If you had problems scaling, then you would shard or pay lots of money for clustered/big iron solutions. NoSQL developed in part as a reaction to the overuse of RDBMSes for all sorts of problems. Of course, it can be hard to say exactly what NoSQL is - but I like to define it as a resurgence of "the right tool for the job," just applied to the storage and persistence space. It can be graph-based, document-based, column-based, or object based -- or even just a data structures server. It is not surprising, though, that Python is able to talk to them all. In this track we have four different talks, giving the inside scoop on production-level use of various NoSQL stores. ZODB: A Python Persistence System by Chris McDonough. The ZODB is the granddaddy of the various NoSQL options for Python, having been developed when such things were "object databases" and not "NoSQL." Nevertheless, the ZODB is a standalone persistence system uniquely integrated into Python that remains astoundingly buzzword-compliant despite its age. This talk will provide a high-level overview of ZODB useful to a novice or intermediate Python programmer. At the end of the talk, an attendee should have a basic understanding of how to create an application which depends on ZODB persistence. CouchDB and Python in practice by Luke Gotszling. CouchDB has a unique document-centric model with automatic clustering and replication. It is gaining a lot of traction, and has recently been seen both up in the clouds and as a data store on Android phones. This talk will introduce CouchDB and will show how to get it to play well with Python. Luke will continue by showing a python ORM for CouchDB, easing development and object-document interoperability. Finally, Luke will cover parsing CouchDB documents within python, writing view functions in python, map/reduce functions on CouchDB from python, and some lessons learned from managing and distributing a live deployment at scale under high load. Scaling Python past 100 by Mark Ramm. Those with eagle eyes will spot this as a repeat from the "web working" track. That is because this talk is a twofer - describing both the development of the modern Python codebase as well as the use of MongoDB to address the scaling issues associated with a top 100 site. MongoDB + Pylons at Catch.com: Scalable Web Apps with Python and NoSQL by Niall O'Higgins. The Catch.com backend provides an API for publishing and querying your personal data - used by many hugely popular Android, iOS and Web clients. Faced with the limits of the initial Catch.com Java/BDB backend implemention, they evaluated various alternative technologies including Amazon SimpleDB, MySQL, Cassandra and MongoDB. They found Python and MongoDB gave them unique flexibility with our data model, allowed them to scale for increased reliability and performance and decreased feature development time - and in this talk they'll describe exactly how. Edit: Wesley Chun points out that Running Django Apps on Google App Engine is also designed to deal with NoSQL datastores - and that the principles covered in his talk apply both to GAE and to MongoDB. ed. Is this the conference you want to see? Then, register for PyCon and book your room now! We have picked up a few more rooms - including a few at a lower rate a block away. You can email (pycon4-reg@cteusa.com), or phone (847-759-4277). We have very few spots left. Edit: Discussion link on Hacker News. No comments:
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Wednesday, May 18, 2011 I can literally feel myself getting to the point of going the fuck off. I've been taking care of a lot of shit in my life and I am greatly satisfied with how things are coming together. Nothing is set in stone right now, but I have options. I do not feel stuck anymore at all. If anything I am so ready to break free of the bullshit and move on that hopefully my anxiousness doesn't make me jump the gun on anything. I'm still trying to be patient and just see what option will be best for me, in the short and long run. But the one thing that I am still dealing with is Him. I just don't even know where to begin. I get mad whenever I talk to him. I don't even really know why. Well I take that back, I know exactly why I get mad, I just don't know why I bother getting mad. That sounds better. I am really getting to the point where Imma just be over it all if something doesn't change soon. Something that lets me know we are moving towards being with each other. But he just not in the mind frame for that. His mind frame is too wrapped into his reality that he has to deal with and he is losing sight of what he really wants. Everything is all about keeping what he has going on together. He trying but fuck that. And what really pisses me off is he acts like he taking this big fucking risk like I have never done anything for him. Everything that happened with him was my worst fear. Shit like what happened is one of the major reasons why I never really wanted to fall in love with somebody. But thats not shit to him though because I didn't lose any money. I just lost my ability to fall in love and really trust somebody ever again. Well i'm exaggerating, but shit he don't know that. That shit really could have fucked me up. And if it wasn't for me talking to his ex and seeing how fucked up she was, I would be down a totally different path right now. Luckily I'm used to not allowing shit to fuck me up for too long, and I can deal with shit and eventually regain my own happiness. I JUST got back to the point where I feel like my old self again. I won't say that he necessarily started the downward spiral but he damn sure catapulted me to what I think was one of my lowest moments ever. I didn't know if I was gonna ever recover from that shit. How do you accept KNOWING that someone would rather be with you but because he had a child, he feels like he should be with his babymama for his child's sake? I see the logic in that but to me everything does not have to make sense in the mind. And it should be a balance between your heart and mind. Because just following one or the other could lead you to some fucked up places. And all I really want him to do is recognize all the shit that I have done FOR HIM. Because I can tell in his mind, he doesn't see where I have done anything for him. Because its not in terms of money or anything that you can physically see. But just how I handled and carried myself in the situation made a lot of difference in how things are playing out today. The things that I could have done and said and been RIGHTFULLY SO would have fucked up a lot of shit for him and his relationship with his son. I recognized that and avoided it despite being disrespected and played as this homewrecker who was trying to fuck up a family. I HAD SO MUCH SHIT THAT I COULD HAVE SAID and it was all truth so there was no way that he would be able to deny it and she would believe me over him anyway. I didn't have to make up lies to make her feel bad like she tried to do with me. I could have crushed her spirit with the truth, but I chose not to because it was not my place to say anything. I cleared my name in the situation because I am not a homewrecker, but as far as telling truths that didn't affect me, I kept all that to myself. He asked me to chill out when things were really crazy and I did. I don't get any credit  for that though. I know he think my mom likes him and there's no doubt in my mind that she doesn't. However, the only reason she still likes him after everything was because of me. She definitely wanted to hate him because she knew how much I liked him and she liked the fact that he made me so happy. So of course, she was ready to say fuck him once i told her what happened, but I made him look like a fucking saint to her compared to how he really made me feel. The only reason any of my friends or family haven't been talking cold shit about his ass is because of me. I didn't allow them to do it. I shut it down as soon as they tried to start. They didn't know him like I did and I didn't want them forming opinions about him based off stuff I said and how I was feeling at the moment. Once again, I looked out for him despite how stupid I had to sound for taking up for somebody that just fucking ripped my heart out and stomped on the motherfucker. But I don't get any credit for that either. I don't get any credit for trying to be understanding about what he was going through and the decisions he had to make concerning everything. I even placed a lot of the blame on myself for a while, and I could have handled things differently but in that moment, i thought what i was doing was the right thing to do. And in a sense I was. I was threatening to stop fucking with him all the time because I was hoping he wouldn't let it happen. I was hoping that he would see that I wasn't playing and he would fix the situation. But he didn't. All he saw was me saying I would leave him, and that probably was not the best thing to be showing him at that time. I recognize that now, but even still, he should have seen it as more than that. He should have known that I didn't want to stop talking to him, but I had to. He was making me feel stupid. I don't give a fuck what somebody else think, but  I can't sit around and be involved in dumb shit regardless of how much I care. I always care about me more. All I'm stuck with nowadays is trying to prove and explain myself because of all the assumptions he wants to make about me and the things that I do towards him when he should KNOW that I have looked out for him from day one. When I would go grocery shopping, I went shopping for both of us. It was no coincidence that I always had shit he liked. For holidays, I made sure I bought him something. I noticed how he had all these cute boxers with sayings and shit, so whenever I would go in stores, I would always go look and see if they had any good ones. Or how I always made it my business to make sure I fucked him very well. Lets not even talk about all the shit that he NEVER got to see for Valentines day and the breakfast I made with heart pancakes and all that shit that I had to just throw away. Or the time I went to go see him and I had $20 to my name for the week until I got paid, and I spent $15 of that on a cab to his house. Or how I got Jennifer to take me around to places where I knew he would be and I made these cute Have you seen my snuggie signs just because I wanted him to know I still cared about him, but I still wanted to respect that we decided to stop talking. And to top that all off, I have NEVER asked him for anything. Well I do remember asking him for some money one time but that was only because I really needed it, but of course, he couldn't give it to me. But that was it. I know for a fact that it is not one thing on this earth that I have come out of my mouth and asked him for. Even with everything not once have I ever told him to leave her or be disrespectful or play her in anyway. I'm sure its easy to tell that I want him to leave her but I never ever asked him to carry her for me. Thats the type of shit she wanted him to do towards me. And another thing thats fucked up is he actually would do it. Like just tell me whatever to make her happy. Just fuck my feelings huh? I don't know why I even get mad anymore. She been working on getting him to carry me for a while. I should be used to it by now. It's so bad now that he carry me all the time and don't even realize it. In whose mind does it make sense for you to call me and ask me about having a threesome with you and a bitch that YOU KNOW I feel some type of way about. And then wonder why I got mad about it. But what really  pissed me off is that he told me HE KNEW I would get mad about it but he asked me anyway because she kept bothering him to do it. I hope the bitch don't ever ask him to kill me or some shit like that. I don't know how far he willing to take it, but if we going off his track record, I'm as good as dead. But I kinda went off an a tangent there. Back to what I was saying...I've always been cool about shit. I didn't start tripping about shit until he started acting stupid. I kept my mouth shut about ALOT of stuff because I would always tell myself he can do whatever he want because he not your boyfriend. I always from day one whenever he called me I would stop whatever I was doing and find a way to get to him. If I didn't give a fuck, I could have easily been like I'm busy. Or I'm not driving right now. I made myself available. When he was coming to my house every weekend without me even asking, I missed a bunch bday parties, thanksgiving and christmas' with my family FOR HIM. Anybody who knows me knows that I am family first so for me to miss thanksgiving and christmas for a nigga, thats serious. And I think thats what hurts me the most now. Throughout everything I never once was on some I dont give a fuck shit. If anything, I cared way too fucking much. I still think I care too much even though I've let a lot of shit go when it comes to the situation, but its still shit that pisses me off because even though I know his intentions are not bad, everything he does towards me comes across like I don't give a fuck about Megan until my dick get hard. We used to talk all the time about everything. He probably knows more about me than a lot of my friends do. I treated him like family. And by family, I mean I inconvenienced myself a lot for his sake. I thought about him before I thought about myself. I let my family do that because I really care and I like to think that if I ever need them, they got me. I guess with my family track record, I really shouldn't be surprised. They definitely didn't help me when I needed it. So the shit hurts my feelings that he only calls me when he can fuck. That's the only time he will make an effort to see me. Not just to see how I'm doing. Or to just chill. But to fuck. Thats the main goal. And then he wanna know why I tell him shit like well if you just wanna fuck somebody, find you a bitch close that you can fuck. You don't need me. If its just pussy you want, then you live with a pussy you can have anytime. Fuck her. I'm sure its bitches around where you live that would give you some ass. Fuck them. And it confuses the fuck out of me when he says shit like I can't stop talking to you. Wait what? Ummm we don't talk. So I can't tell. It seems like you have no problem not talking to me. He doesn't ever just call me to talk. If I get a message from him I already know he must have a window of opportunity to come fuck me. So maybe he can't stop wanting to fuck me. That would make more sense to me. Because that matches up with his actions and the things that I can tell from observation. He says he don't just be talking good shit, but he never acts on it, so either way, its just words until he starts acting on them. It just hurts because I actually really fucking care despite all the bullshit and at the end of the day I really appreciate all the time we spent, and him bringing me pads, and cooking me thanksgiving dinner, and calling me everyday to talk and making an effort to come see me on the weekends so im not in the house alone. I was feeling real fucked up about how my family was treating me and he really helped me deal with all that. And im sure he doesn't even know it. He was the only person that I could depend on and that I fucked with up here. It was just the fact that he was there. And I miss having somebody looking out for me and my best interests. Somebody I can trust and be myself with. And I am not sure if he will ever realize how much I mean everything I say to him. Cause if I didn't really love him and give a fuck, I would have been done WAY before a child ever came into the picture. Hopefully something will get through to him one day. *sigh* Seventeen Daily Freebie
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Reviews > Television Sue Thomas: F.B.Eye Television | Original series on PAX-TV network has something for the whole family Issue: "2004 Election: GOP's encore," Aug. 28, 2004 One of the top shows for families, according to the Parents Television Council, is Sue Thomas: F.B.Eye, an original series on the positive-values network PAX-TV. Another series from the Christian television team of Gary and Dale Alan Johnson, the show is based on the real-life career of Sue Thomas, an FBI agent who is deaf. The role is played by Deanna Bray, a deaf actress. One theme of the program is how well deaf people can function in the "hearing world." Both the real and the fictional Sue Thomas got her start as a fingerprint analyst, but the agency discovered that her ability to read lips is priceless when it comes to long-distance surveillance. Agent Thomas can read the bad guys' lips through her binoculars, which means undercover agents do not have to risk their lives if their "wires" are discovered. Sue Thomas is a cop show, so sometimes people get killed, but there is no blood and little violence to speak of. There is no cynicism in the FBI team, no "gritty realism" as is common on the new breed of cop shows. Typically, Sue Thomas has two plots: a crime story (such as trying to catch an al-Qaeda arms dealer) and a personal story of one of the regular characters (a husband has trouble coming to terms with his wife's pregnancy). The show has "sweet" moments (the husband buying a pair of booties for the new baby) and some tear-jerking moments (after all that, the wife has a miscarriage). It has forensic moments (deducing the location of the bad guys' hideout by calculating the length of a car ride) and police moments (breaking in on the terrorists). It also has sweet police moments (catching a fleeing arms merchant by realizing that he must pick up his daughter at school; he won't fight arrest because it might embarrass her, so they don't cuff him to embarrass him). Now in its third season, Sue Thomas: F.B.Eye does not have as many overt statements of faith as does the Johnson brothers' other show for Pax, Doc. But it is unrelentingly positive. With its relationship plots, its inspiring role model, and just enough gunplay to spice things up, the show has something for the whole family. Gene Edward Veith Gene Edward Veith You must be a WORLD member to post comments. Keep Reading The premise of Calvary , in limited release Aug.
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Welcome to Reception Welcome to Reception! We are Mrs Reed and Mrs Ungless (Goslings) and Mrs Ranson (Duckling). We are supported in Reception by Mrs Duncan, Mrs Gardner and Mrs Cowell, our fantastic Teaching Assistants. Reception is an exciting year and is about building the foundations for children to make the most of their abilities and talents through their learning journey. We believe that every child is unique and it is therefore important to build positive relationships in a secure and stimulating environment. We provide children with a rich in and outdoor environment where they can learn and develop to their full potential. In Reception, learning is built around the child's needs and interests and children are encouraged to become independent life-long learners. The best learning happens through fun play-based activities. We understand that the child's learning journey is a partnership between home and school. We have an open door policy and encourage parents to participate in their child's school life. Look forward to working with you all. Mrs Ungless, Mrs Reed, Mrs Ranson and the Reception Team Mrs Ungless Gosling Teacher Mrs Reed Gosling Teacher Mrs Ranson Duckling Teacher
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The Greatest Joke (According to Iliza Shlesinger) A man and a woman go on a game show, like a Password kind of game, and the guy has to draw a note card. On the note card is a word, and the woman has to ask questions to guess what the word is, and the guy can only answer yes or no. So the announcer's like, "Your time begins now!" And the guy picks up the note card and he's looking at the word on the note card, and he can't believe it because the word is horsecock. The guy's sweating and he's thinking, How is she going to guess this? How is this ever going to happen? The woman starts asking questions: "Um . . . I don't know where to begin. Is it something I could put in my mouth?" The guy's standing there unsure, and he's like thinking and he's like, "Yeah, technically, yes, it is something you could put in your mouth, yep." And the woman goes, "Um, okay . . . is it horsecock?" —ILIZA SHLESINGER ABOUT THE COMEDIAN: Iliza Shlesinger shouts for her dog Blanche while she waits onstage to tell her favorite joke. The dog is sniffing around the Comedy Store in Los Angeles, where Shlesinger performs so often that she has free rein of the venue (and, in fact, she takes the Esquire crew on a historical tour of the building that involves ghosts and murders). "Stay away," Shlesinger tells Blanche as she takes the mic. "This is not your moment." "The idea of the funniest joke you've ever heard is so daunting if you've been doing comedy for more than 10 minutes," says the comedian, who won the sixth season of Last Comic Standing and recently released a Netflix special called Freezing Hot. "There are so many jokes and you also want a joke that's sort of reflective of what you are as a comic." Her choice? "It all just came back to this one joke I heard in high school. It's really the only street joke I've ever told more than once. I don't know who wrote it, but I heard it from my friend Elliott." Shlesinger has a pretty concrete idea of what makes a joke great. "I think comedy comes from two places. One, what the comic is saying is so out there and so wholly unrelatable that you're laughing because it's shocking. And two, because it's so relatable that it resonates with something deep within you and you immediately identify with that comic. You're laughing at yourself, in a weird way." The latter is true for Shlesinger's comedy, which tackles ideas of gender and relationships. She takes aim at women who love Pinterest, dating, and crazy breakup scenarios in her stand-up. "It's almost a vulnerable feeling when you relate to a comic. It's like 'How do they know my heart?'" Advertisement - Continue Reading Below
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Bar/fly: India's Palace on Wheels By Kevin Pilley The "Palace on Wheels" is an extravagant week you won't forget, writes Kevin Pilley. The passengers of the 14-carriage 'Palace on Wheels' are called 'POWs'. Illustration / Rod Emmerson The whisky-wallah poured out our Red Blazers. Arthur made the toast. "To the POWs!" We chinked and swallowed, shuddering simultaneously. Arthur then tempted me with a Black Dog. Neither of us trusted the ice. And both said a polite but stern "No" to the fish finger canapes. Our eyes watered. "Indian whisky's an acquired taste. It's a real culture shock," observed Arthur, a "semi-retired" Kiwi GP. And stubbornly not Art or Arty. We were on a moving palace and making our way through the Rajasthan night and the top shelf of the train's bar. The "khidmatgars" or personal attendants hovered. India's "Palace on Wheels" has the reputation of being one of the most luxurious "escorted" train journeys of the world. It runs throughout the year but takes a break from May to July. The journey departs from and returns to New Delhi's Safdarjung station. The seven-day, quite-a-lot-of-money, "week in wonderland" trip around "man-made marvels and the wonders of nature" is further described in the official guff as "a splendid and enchanting royal journey through the bygone era of the erstwhile Maharajahs". Passengers are given a welcoming "arrival kit", comprising a garland of wilted marigold petals, six postcards, no stamps, a fetching sandalwood paste dot in mid-forehead and a complimentary turban. As well as an option on a Dutch wife. The third eye is an Indian custom. The turban is a red handkerchief stapled very cleverly to a brown paper carrier bag which means it will keep its shape even if you fall asleep in it. The Dutch wife is an optional, body-length pillow used as a his-or-hers bed bolster. Travelling through the night in "plush" berths complete with en suite ("attached") toilets and "luxury geysers" (showers), you wake up every morning to a new city and a new scrum of hawkers. Everyone wants to see the legendary "Palace on Wheels". Meeting it is a social occasion. Selling worthless things to those on board is a time-honoured custom. And a respectable way of making a living. The passengers of the 14-carriage "Palace on Wheels" are called "POWs". Everyone rolls out the carpets. Especially the owners of the state-run handicraft shops that seem an integral part of every day's sightseeing itinerary. The Palace is further billed as "an extraordinary train for extraordinary people". For many passengers around "The Golden Triangle" the highlight of the tour is the Taj Mahal. For others, it's the jolting ride in a howdah on an elderly, arthritic elephant to the 16th-century "Pink Fort" of Jaipur. But not back. The piles can't handle it. Others praise the visit to the Ranthambhore National Park. Or the evening spent under the stars in the Sam Sand Dunes in the Thar desert of Rajasthan. Watching local ladies undulate their midriffs and show off their bangles. My highlight was meeting fellow POWs in the train's bar, a focal point of world culture. Of the 70 on board, I got to know a very serious Indian train buff who informed me India boasts the longest train station name in the world. Venkatanarasimharajuvaripeta. Try saying that after a few. There was a couple of South African sugarcane farmers who had just attended a molasses conference in Delhi. A French couple onboard didn't like each other very much and showed it by never talking to each other. We also had a pair of sullen Spaniards and a strange and conspicuously single man from God-knows-where who stared at me all the time. And often shook his head. Plus: A couple of honeymooning "Puppies" who introduced themselves as "Punjabi yuppies". And a Dick van Dyke look-a-like from California. And Rex and Sheila, Brits who had gravitated to Zimbabwe. Rex had a pronounced limp that seemed to get progressively better as each day wore on, to the point of disappearing altogether by the evening. I asked him about it as we lunched in the bar. "The explanation is quite simple, old boy." With a twinkle in his eye, he reached into the pocket of his shorts and brought out a hipflask. "Gets me through the distances and sees off the Delhi belly. It's full in the morning and gets lighter as time goes by. By the end of the day it's empty and therefore it's easier to walk. My movements aren't so restricted." But the real highlight was Indian-born Arthur and his Kiwi wife Pam, who confessed - after a few drinks, many laughs and one public convulsion - that she was a former New Zealand junior roller skating champion. There are many things people divulge while wearing a turban and drinking in the scenery, whisky and atmosphere of India. Getting there: Cathay Pacific has same-day connections from Auckland, via Hong Kong, to Delhi, Mumbai, Chennai and Bangalore. Get the news delivered straight to your inbox © Copyright 2016, NZME. Publishing Limited Assembled by: (static) on production apcf05 at 01 Jul 2016 14:57:37 Processing Time: 1285ms
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30' x 40'' Intertwined 2 36'' x 48'' Invisible Bond 30'' x 30'' Intertwined 1 36'' x 48'' Intertwined 6 (Sold) 30'' x 40'' Intertwined 3 36'' x 48'' Intertwined 4 36'' x 48'' Love, a connection between two souls that stand like pillars holding up a shelter called Life. They stand next to each other, distinct but connected, each giving strength to the other to endure all the hardship, sorrows and pain that destiny has in store. And it is this love that truly colors their life with light and eternal memories of happiness...
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Friday #StrideInspiration | NBC Chicago Tips, Tricks and Gear Recommendations for Chicago Runners Friday #StrideInspiration It can be tough to get yourself on track. Sometimes you give up, and sometimes you have to fight like crazy to just lace your shoes. Runners know this better than almost anyone, and when you're waging a mental battle, deterrents like bad weather or an ever-growing to-do list can be detrimental. So if you're in need of some #StrideInspiration like me, check out this quote by Paul Maurer, author of The Gift: A Runner's Story:  So when you're powering through a long Saturday morning run this weekend, keep in mind that powering through the setbacks and the self-doubt can be just the key to making you a better runner. What's keeping you inspired to hit the pavement this weekend? Tweet it to us at @StrideNBC with the hashtag #StrideInspiration!
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Why do we often have a fearful aversion to sharing the most important good news ever— news that means life or death for every single person? Let me count the ways: fear, rejection, anxiety, foolishness, embarrassment, not enough information, shyness, or “I’m at work!”, to list just a few. But might I suggest that the true reluctance comes mostly from a few misperceptions… Church Awake Podcast Subscribe to the Church Awake podcast on your favorite podcast player--just search "Church Awake"! Don't have a player? Don't worry, you can find all of our episodes here at CharlotteAwake.com.
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The downloads page doesn't have links. The source is on github. Are we supposed to build the app ourselves? I got my CBT today and want to get to figuring out how to read from my Chrysler T&C. I'm still finishing up the app, sorry for the delay. Right now you have to dump packets over USB Serial. For more info on that see here: Once the app is ready for beta I will post downloads and push it to app stores. Right now I wouldn't worry about building it from source unless you really have some time to kill. :) Got it. So in the mean time, can I just hook up a laptop and terminal program and try to view the data stream from the vehicle? Is there enough in place for that? Yeah totally. I know it's a pain but until the app is ready that's what we have. You can modify the base firmware to do stuff your way too if you have ideas. I cleaned up and updated the app, made it easier to build etc last night. I'll hopefully be able to release the alpha of the desktop version shortly. Got a lot done this weekend. Going to test on all desktop platforms and post beta downloads hopefully tonight or tomorrow. I got sidetracked a little and wrote an adapter to feed packets into Wireshark for people who want that. It will be integrated into the desktop app as well! Had a look at the Wireshark part but to much trouble for me. I'm more of a car guy than a programmer ;-) Looking forward to the apps! Followed the instructions for Wireshark. I can run the node.js app, it creates the /tmp/cbtbus1 pipe (works only when run with sudo). When I start Wireshark and add the interface all seems well. But when I start the capture process I get the message "The capture session coud not be initiated due to error on socket connect: Connection refused". I tried running Wireshark as root (start with sudo from command line) or change the permissions on /tmp/cbtbus1 but none of this gets me passed the error. When I start the node.js app as a normal user I get this error: Socket bound: /tmp/cbtbus1 throw er; // Unhandled 'error' event Error: Cannot open /dev/cu.usbmodem641 When run with sudo it creates the pipe but Wireshark returns 'connection refused'. I assume /dev/cu.usbmodem641 is the correct path? When you have the CBT plugged in run 'ls /dev/cu.usb*' and it should list your usb serial devices. Make sure you're not connected to the CBT with other software or it will not work. Yes, I checked the path which is correct and I am not using any other software... @henk_kuipers: My CBT was listed under /dev/ttyACM0 which is where all my serial devices seem to show up (Ninja Sphere, USB 56k modem etc.). I'm on Ubuntu 14.04 LTS with no other software (that I know of) connecting to the CBT Hi Grayda, the path in of the serial device is not the problem. The node.js app runs and creates the pipe /tmp/cbtbus1 correctly. Also, when the path to the serial device is incorrect, the node.js app won't start, which it does. There seems to be some problem with the rights / access but haven't figured out what. What platform are you on @henk? I made some updates to the code, give it another go and maybe try running node with sudo if you're on unix. @Derek I am running it on OSX Yosemite, npm version 2.7.5, node v0.12.2 and I cloned the latest code today. The problem is the node app starts up when I run: node index.js /dev/cu.usbmodem411 and it returns: Socket bound: /tmp/cbtbus1 Socket bound: /tmp/cbtbus2 Socket bound: /tmp/cbtbus3 Logging enabled on all three busses But then it exits, without any error message. It should stay running shouldn't it? The cbtbus1-3 files are created in /tmp. Somehow, there is a problem in my environment :-/ I tried it with a friend on another OSX machine and it ran fine. Any update on the apps? I can see there is being worked on but while some may be able (and willing) to generate their own apps from code I would be more interested in trying one of the finished ones. Either Windows or Mac would be fine. @henk_kuipers‌ That's odd, I'm testing on node 0.12.0 I'll try 0.12.2 Had a look at the apps. I've got two old XP laptops for fiddling with my cars. Is there only a 64 bit windows version? @Derek, switched to Windows 8.1 64 bit. Works well! • 20 • 9153
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Brainmap: Cognition is Rhythmic Wednesday, December 18, 2013 - 12:00 Seminar room 2204, 149 13th St., Charlestown Navy Yard Earl Miller The Picower Institute for Learning and Memory and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, How are some thoughts favored over others?  A wealth of data at the level of single neurons has yielded candidate brain areas and mechanisms for our best understood model: visual attention.  Recent work has naturally evolved toward efforts at a more integrative, network, understanding.  It suggests that focusing attention arises from interactions between widespread cortical and subcortical networks that may be regulated via their rhythmic synchronization.  This could extend to all cognitive processes, suggesting our brain does not operate continuously, but rather discretely, with pulses of activity routing packets of information.  Such discrete cycles would provide a backbone for coordinating computations (and their results) across disparate networks.  However, it comes at a cost: it is naturally limited in bandwidth; only so many things can be computed or carried in a single oscillatory cycle. This can explain the most fundamental property of conscious thought, its limited capacity, which is the reason why we evolved attention in the first place.
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Pete Swenson Pete Swenson (born December 25, 1967) from Breckenridge, Colorado, is an American ski mountaineer and Competition Director of the United States Ski Mountaineering Association (USSMA). Swanson attended the Colorado College until 1990. Selected results 2006: 9th, World Championship, relay, together with Cary Smith, Chris Kroger and Steve Romeo 2009: 1st, US Ski Mountaineering National Championship, Jackson Hole 2010: 2nd (seniors II), Patrouille des Glaciers, together with Benedikt Böhm and Javier Martín de Villa External links Pete Swenson at skimountaineers.org 2008 USSMA Season Points References Category:1967 births Category:Living people Category:American male ski mountaineers Category:Sportspeople from Colorado Category:People from Breckenridge, Colorado
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