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Knowledge about time trends of cancer incidence and cancer survival in a defined region is an essential prerequisite for the planning of regional healthcare infrastructure. The aim of the study was to provide population-based analyses of all common tumour sites to assess the cancer burden in the Augsburg study region. ... | Trends in cancer incidence and survival in the Augsburg study region-results from the Augsburg cancer registry. | BMJ open | medicine | 337 | 43 |
To examine the prevalence of dehydration without diarrhoea among admitted children aged 1-59 months and to describe fluid management practices in such cases. A multisite observational study that used routine in-patient data collected prospectively between October 2013 and December 2018. Study conducted in 13 county ref... | Prevalence and fluid management of dehydration in children without diarrhoea admitted to Kenyan hospitals: a multisite observational study. | BMJ open | medicine | 337 | 43 |
Suicidality among sexual minority adolescents has generated worldwide concern in recent decades, and previous Western studies have demonstrated that sexual minority status is associated with adolescent suicidality. However, whether this association exists in Chinese adolescents remains largely unknown. This study aimed... | Sexual minority status and suicidal behaviour among Chinese adolescents: a nationally representative cross-sectional study. | BMJ open | medicine | 337 | 43 |
To determine whether there is a relation between statin utilisation and coronary heart disease (CHD) mortality in populations with different levels of coronary risk, and whether the relation changes over time. Ecological study using national databases of dispensed medicines and mortality rates. Western European countri... | Time trends in statin utilisation and coronary mortality in Western European countries. | BMJ open | medicine | 337 | 43 |
The quality of ambulatory care in Switzerland is widely unknown. Therefore, this study aimed to evaluate the recently proposed quality indicators (QIs) based on a nationwide healthcare claims database and determine their association with the risk of subsequent hospitalisation at patient-level. Retrospective cohort stud... | Evidence-based quality indicators for primary healthcare in association with the risk of hospitalisation: a population-based cohort study in Switzerland. | BMJ open | medicine | 337 | 43 |
(1) Assess the population-level probability of prenatal diagnosis and termination of pregnancy for fetal anomaly for four major congenital heart defects; (2) Examine, using population-based data, the relation between timing of (prenatal vs postnatal) diagnosis and risk of infant (ie, < 1 year) mortality for four major ... | Impact of prenatal diagnosis on survival of newborns with four congenital heart defects: a prospective, population-based cohort study in France (the EPICARD Study). | BMJ open | medicine | 337 | 43 |
To identify the research priorities for medical nutrition education worldwide. A 5-step stakeholder engagement process based on methodological guidelines for identifying research priorities in health. 277 individuals were identified as representatives for 30 different stakeholder organisations across 86 countries. The ... | Setting priorities for research in medical nutrition education: an international approach. | BMJ open | medicine | 337 | 43 |
The creatine kinase circuit is central to the regulation of high-energy phosphate metabolism and the maintenance of cellular energy turnover. This circuit is fuelled by creatine, an amino acid derivative that can be obtained from a diet containing animal products, and by synthesis in the body de novo. A recent retrospe... | Creatine and pregnancy outcomes, a prospective cohort study in low-risk pregnant women: study protocol. | BMJ open | medicine | 337 | 43 |
Evaluating the efficacy of a laparoscopically guided, surgical transversus abdominis plane (TAP) and rectus sheath (RS) block in reducing analgesic consumption while improving functional outcomes in patients undergoing laparoscopic bariatric surgery. 150 patients Living with obesity undergoing elective laparoscopic Rou... | Randomised, double-blinded, placebo-controlled trial to investigate the role of laparoscopic transversus abdominis plane block in gastric bypass surgery: a study protocol. | BMJ open | medicine | 337 | 43 |
CD8+ T cell immune monitoring aims at measuring the size and functions of antigen-specific CD8+ T cell populations, thereby providing insights into cell-mediated immunity operational in a test subject. The selection of peptides for ex vivo CD8+ T cell detection is critical because within a complex antigen exists a mult... | Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance. | Frontiers in immunology | immunology | 988 | 37 |
Natural killer (NK) cells are cytotoxic innate lymphocytes that are well-known for their ability to kill infected or malignant cells. Beyond their roles in tumor surveillance and anti-pathogen defense, more recent studies have highlighted key roles for NK cells in a broad range of biological processes, including metabo... | Transcriptional Regulation of Mouse Tissue-Resident Natural Killer Cell Development. | Frontiers in immunology | immunology | 988 | 37 |
Conjunctival epithelium forms a barrier between the ocular surface microbial flora and the ocular mucosa. In addition to secreting gel-forming mucins, goblet cells, located in the conjunctival epithelium, help maintain local immune homeostasis by secreting active TGFβ2 and promoting tolerogenic phenotype of dendritic c... | Conjunctival Goblet Cell Responses to TLR5 Engagement Promote Activation of Local Antigen-Presenting Cells. | Frontiers in immunology | immunology | 988 | 37 |
Myeloid cells are a major heterogeneous cell population in the tumor immune microenvironment (TIME). Imbalance of myeloid response remains a major obstacle to a favorable prognosis and successful immune therapy. Therefore, we aimed to construct a risk model to evaluate the myeloid contexture, which may facilitate the p... | Comprehensive Analysis of Myeloid Signature Genes in Head and Neck Squamous Cell Carcinoma to Predict the Prognosis and Immune Infiltration. | Frontiers in immunology | immunology | 988 | 37 |
Dramatic progress in the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) from alternative sources in pediatric patients has been registered over the past decade, providing a chance to cure children and adolescents in need of a transplant. Despite these advances, transplant-related mortality du... | Harnessing T Cells to Control Infections After Allogeneic Hematopoietic Stem Cell Transplantation. | Frontiers in immunology | immunology | 988 | 37 |
Emerging evidence indicates that gut dysbiosis may play a regulatory role in the onset and progression of Huntington's disease (HD). However, any alterations in the fecal microbiome of HD patients and its relation to the host cytokine response remain unknown. The present study investigated alterations and host cytokine... | Altered Gut Microbiota Related to Inflammatory Responses in Patients With Huntington's Disease. | Frontiers in immunology | immunology | 988 | 37 |
Accumulation of somatic hypermutation (SHM) is the primary mechanism to enhance the binding affinity of antibodies to antigens in vivo . However, the structural basis of the effects of many SHMs remains elusive. Here, we integrated atomistic molecular dynamics (MD) simulation and data mining to build a high-throughput ... | Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation. | Frontiers in immunology | immunology | 988 | 37 |
Neutrophils are key pathogen exterminators of the innate immune system endowed with oxidative and non-oxidative defense mechanisms. More recently, a more complex role for neutrophils as decision shaping cells that instruct other leukocytes to fine-tune innate and adaptive immune responses has come into view. Under home... | Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of Systemic Juvenile Idiopathic Arthritis. | Frontiers in immunology | immunology | 988 | 37 |
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of immunity, there has been no systematic attempt to identify and characterize the lncRNAs whose expression is changed following the induction of the innate immune response. To address this issue, we have employed next-gene... | Catalog of Differentially Expressed Long Non-Coding RNA following Activation of Human and Mouse Innate Immune Response. | Frontiers in immunology | immunology | 988 | 37 |
The number of diabetic patients in Europe and world-wide is growing. Diabetes confers a 2-fold higher risk for vascular disease. Lack of insulin production (Type 1 diabetes, T1D) or lack of insulin responsiveness (Type 2 diabetes, T2D) causes systemic metabolic changes such as hyperglycemia (HG) which contribute to the... | Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions. | Frontiers in immunology | immunology | 988 | 37 |
Human CD52 is a small glycopeptide (12 amino acid residues) with one N- linked glycosylation site at asparagine 3 (Asn3) and several potential O- glycosylation serine/threonine sites. Soluble CD52 is released from the surface of activated T cells and mediates immune suppression via its glycan moiety. In suppressing act... | Specific Sialoforms Required for the Immune Suppressive Activity of Human Soluble CD52. | Frontiers in immunology | immunology | 988 | 37 |
The peripheral nervous system consists of sensory circuits that respond to external and internal stimuli and effector circuits that adapt physiologic functions to environmental challenges. Identifying neurotransmitters and neuropeptides and the corresponding receptors on immune cells implies an essential role for the n... | An Integrated View on Neuronal Subsets in the Peripheral Nervous System and Their Role in Immunoregulation. | Frontiers in immunology | immunology | 988 | 37 |
The dynamic nature of the SIV population during disease progression in the SIV/macaque model of AIDS and the factors responsible for its behavior have not been documented, largely owing to the lack of sufficient spatial and temporal sampling of both viral and host data from SIV-infected animals. In this study, we detai... | Predator-Prey Dynamics of Intra-Host Simian Immunodeficiency Virus Evolution Within the Untreated Host. | Frontiers in immunology | immunology | 988 | 37 |
Although various immunotherapies have exerted promising effects on cancer treatment, many patients with cancer continue to exhibit poor responses. Because of its negative regulatory effects on T cells and its biological functions related to immune and inflammatory responses, there has been considerable emphasis on a pr... | Research Progress Concerning Dual Blockade of Lymphocyte-Activation Gene 3 and Programmed Death-1/Programmed Death-1 Ligand-1 Blockade in Cancer Immunotherapy: Preclinical and Clinical Evidence of This Potentially More Effective Immunotherapy Strategy. | Frontiers in immunology | immunology | 988 | 37 |
Maternal RhD alloimmunization is an inflammatory response against protein antigens in fetal red blood cells (RBC). However, not all women become alloimmunized when exposed to RhD + fetal RBC. Thus, this study aimed to evaluate levels of inflammatory chemokines in RhD - pregnant women with erythrocyte alloimmunization. ... | High Levels of CXCL8 and Low Levels of CXCL9 and CXCL10 in Women with Maternal RhD Alloimmunization. | Frontiers in immunology | immunology | 988 | 37 |
Clinically, immune cell function is correlated with pathogenesis of endometrial polyp (EP) and infertility of women of reproductive-age. However, the underlying immune cell hallmark in EP patients remains unclear. Here, we focused on analyzing circulating immune cells, and attempted to reveal the correlation between pe... | Circulating PD1+Vδ1+γδ T Cell Predicts Fertility in Endometrial Polyp Patients of Reproductive-Age. | Frontiers in immunology | immunology | 988 | 37 |
Periodontitis increases the risk of nonalcoholic fatty liver disease (NAFLD); however, the underlying mechanisms are unclear. Here, we show that gut dysbiosis induced by oral administration of Porphyromonas gingivalis , a representative periodontopathic bacterium, is involved in the aggravation of NAFLD pathology. C57B... | Oral Pathobiont-Induced Changes in Gut Microbiota Aggravate the Pathology of Nonalcoholic Fatty Liver Disease in Mice. | Frontiers in immunology | immunology | 988 | 37 |
Cytotoxic T lymphocytes (CTLs) have been suggested to play an important role in controlling human immunodeficiency virus (HIV-1 or simply HIV) infection. HIV, due to its high mutation rate, can evade recognition of T cell responses by generating escape variants that cannot be recognized by HIV-specific CTLs. Although H... | Kinetics of HIV-Specific CTL Responses Plays a Minimal Role in Determining HIV Escape Dynamics. | Frontiers in immunology | immunology | 988 | 37 |
The anti-inflammatory effect of an α7nAChR agonist, PNU-282987, has previously been explored in the context of inflammatory disease. However, the effects of PNU-282987 on type 2 innate lymphoid cells (ILC2s)-mediated allergic airway inflammation has not yet been established. To determine the effects of PNU-282987 on th... | A Selective α7 Nicotinic Acetylcholine Receptor Agonist, PNU-282987, Attenuates ILC2s Activation and Alternaria-Induced Airway Inflammation. | Frontiers in immunology | immunology | 988 | 37 |
Bacterial cells in their natural environments encounter rapid and large changes in external osmolality. For instance, enteric bacteria such as Escherichia coli experience a rapid decrease when they exit from host intestines. Changes in osmolality alter the mechanical load on the cell envelope, and previous studies have... | Hyperosmotic Shock Transiently Accelerates Constriction Rate in Escherichia coli. | Frontiers in microbiology | microbiology | 990 | 44 |
Iris yellow spot, caused by Iris yellow spot orthotospovirus (IYSV) (Genus: Orthotospovirus , Family: Tospoviridae ), is an important disease of Allium spp. The complete N gene sequences of 142 IYSV isolates of curated sequence data from GenBank were used to determine the genetic diversity and evolutionary pattern. In ... | Viruses Without Borders: Global Analysis of the Population Structure, Haplotype Distribution, and Evolutionary Pattern of Iris Yellow Spot Orthotospovirus (Family Tospoviridae, Genus Orthotospovirus). | Frontiers in microbiology | microbiology | 990 | 44 |
Antimicrobial resistance (AMR) is one of the most significant threats to global public health. As antibiotic failure is increasing, phages are gradually becoming important agents in the post-antibiotic era. In this study, the therapeutic effects and safety of kpssk3, a previously isolated phage infecting carbapenem-res... | Safety and Efficacy of a Phage, kpssk3, in an in vivo Model of Carbapenem-Resistant Hypermucoviscous Klebsiella pneumoniae Bacteremia. | Frontiers in microbiology | microbiology | 990 | 44 |
While modern developments in agriculture have allowed for increases in crop yields and rapid human population growth, they have also drastically altered biogeochemical cycles, including the biotransformation of nitrogen. Denitrification is a critical process performed by bacteria and fungi that removes nitrate in surfa... | Increased Denitrification Rates Associated with Shifts in Prokaryotic Community Composition Caused by Varying Hydrologic Connectivity. | Frontiers in microbiology | microbiology | 990 | 44 |
The time-to-result for culture-based microorganism recovery and phenotypic antimicrobial susceptibility testing necessitates initial use of empiric (frequently broad-spectrum) antimicrobial therapy. If the empiric therapy is not optimal, this can lead to adverse patient outcomes and contribute to increasing antibiotic ... | Evaluation of Machine Learning and Rules-Based Approaches for Predicting Antimicrobial Resistance Profiles in Gram-negative Bacilli from Whole Genome Sequence Data. | Frontiers in microbiology | microbiology | 990 | 44 |
While vegetation has intensively been surveyed on mountain summits, limited knowledge exists about the diversity and community structure of soil biota. Here, we study how climatic variables, vegetation, parent material, soil properties, and slope aspect affect the soil microbiome on 10 GLORIA (Global Observation Resear... | The Soil Microbiome of GLORIA Mountain Summits in the Swiss Alps. | Frontiers in microbiology | microbiology | 990 | 44 |
Sub-acute ruminal acidosis (SARA) is a gastrointestinal functional disorder in livestock characterized by low rumen pH, which reduces rumen function, microbial diversity, host performance, and host immune function. Dietary management is used to prevent SARA, often with yeast supplementation as a pH buffer. Almost nothi... | An Investigation into Rumen Fungal and Protozoal Diversity in Three Rumen Fractions, during High-Fiber or Grain-Induced Sub-Acute Ruminal Acidosis Conditions, with or without Active Dry Yeast Supplementation. | Frontiers in microbiology | microbiology | 990 | 44 |
Intercropping influences the soil microbiota via litter and root exudate inputs, but the mechanisms by which root exudates mediate the soil microbial community and soil organic matter (SOM) are still unclear. In this study, we selected three aromatic plants ( Ocimum basilicum , Tr1; Satureja hortensis , Tr2; Ageratum h... | Intercropping With Aromatic Plants Increased the Soil Organic Matter Content and Changed the Microbial Community in a Pear Orchard. | Frontiers in microbiology | microbiology | 990 | 44 |
The influence of water and nitrogen (N) management on wheat have been investigated, but studies on the impact of long-term interactive water and N management on microbial structure and function are limited. Soil chemical properties and plants determine the soil microbial communities whose functions involved in nutrient... | Bacterial Community Structure and Predicted Function in Wheat Soil From the North China Plain Are Closely Linked With Soil and Plant Characteristics After Seven Years of Irrigation and Nitrogen Application. | Frontiers in microbiology | microbiology | 990 | 44 |
Bacterial brain abscesses (BAs) are difficult to treat with conventional antibiotics. Thus, the development of alternative therapeutic strategies for BAs is of high priority. Identifying the virulence determinants that contribute to BA formation induced by Staphylococcus aureus would improve the effectiveness of interv... | Virulence Determinants Are Required for Brain Abscess Formation Through Staphylococcus aureus Infection and Are Potential Targets of Antivirulence Factor Therapy. | Frontiers in microbiology | microbiology | 990 | 44 |
Chlamydia trachomatis is the major cause of infectious blindness and represents the most common bacterial sexually transmitted infection worldwide. Considering the potential side effects of antibiotic therapy and increasing threat of antibiotic resistance, alternative therapeutic strategies are needed. Previous studies... | Water Filtered Infrared A and Visible Light (wIRA/VIS) Irradiation Reduces Chlamydia trachomatis Infectivity Independent of Targeted Cytokine Inhibition. | Frontiers in microbiology | microbiology | 990 | 44 |
The use of bacteriophages as therapeutic agents is hindered by their narrow and specific host range, and by a lack of the knowledge concerning the molecular mechanism of receptor recognition. Two P2-like coliphages, named P88 and pro147, were induced from Escherichia coli strains K88 and DE147, respectively. A comparis... | Inducible Prophage Mutant of Escherichia coli Can Lyse New Host and the Key Sites of Receptor Recognition Identification. | Frontiers in microbiology | microbiology | 990 | 44 |
Microalgal species are potential resource of both biofuels and high-value metabolites, and their production is growth dependent. Growth parameters can be screened for the selection of novel microalgal species that produce molecules of interest. In this context our review confirms that, autotrophic and heterotrophic org... | A Review on the Assessment of Stress Conditions for Simultaneous Production of Microalgal Lipids and Carotenoids. | Frontiers in microbiology | microbiology | 990 | 44 |
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an urgent public health problem worldwide, and its rapid evolution in the clinical environment has been a major concern. A total of 99 CRKP isolates spreading in the intensive care unit (ICU) setting were included and subjected to whole-genome sequencing, and their s... | The Emergence of Novel Sequence Type Strains Reveals an Evolutionary Process of Intraspecies Clone Shifting in ICU-Spreading Carbapenem-Resistant Klebsiella pneumoniae. | Frontiers in microbiology | microbiology | 990 | 44 |
The obligate intracellular pathogen Chlamydia trachomatis (Ctr) is the causative agent of the most common form of sexually transmitted disease in the United States. Genital infections with C. trachomatis can lead to inflammatory tissue damage followed by scarring and tissue remodeling during wound healing. Extensive sc... | Alternatively Activated Macrophages Are Host Cells for Chlamydia trachomatis and Reverse Anti-chlamydial Classically Activated Macrophages. | Frontiers in microbiology | microbiology | 990 | 44 |
Recent development in genome editing technologies has enabled site-directed deprivation of a nucleotide sequence in the chromosome in mammalian cells. Human immunodeficiency (HIV) infection causes integration of proviral DNA into the chromosome, which potentially leads to re-emergence of the virus, but conventional tre... | Specific Destruction of HIV Proviral p17 Gene in T Lymphoid Cells Achieved by the Genome Editing Technology. | Frontiers in microbiology | microbiology | 990 | 44 |
Similar to what has been described in other Gram-negative bacteria, Brucella melitensis releases outer membrane vesicles (OMVs). OMVs from B. melitensis 16M and the rough-mutant B. melitensis VTRM1 were able to induce a protective immune response against virulent B. melitensis in mice models. The presence of some prote... | Outer Membrane Vesicles From Brucella melitensis Modulate Immune Response and Induce Cytoskeleton Rearrangement in Peripheral Blood Mononuclear Cells. | Frontiers in microbiology | microbiology | 990 | 44 |
Helicobacter pylori is a pathogen involved in gastric diseases such as ulcers and carcinomas. H. pylori's urease is an important virulence factor produced in large amounts by this bacterium. In previous studies, we have shown that this protein is able to activate several cell types like neutrophils, monocytes, platelet... | A New Role for Helicobacter pylori Urease: Contributions to Angiogenesis. | Frontiers in microbiology | microbiology | 990 | 44 |
The cell surface of Gram-negative bacteria usually exhibits a net negative charge mostly conferred by lipopolysaccharides (LPS). This property sensitizes bacterial cells to cationic antimicrobial peptides, such as polymyxin B, by favoring their binding to the cell surface. Gram-negative bacteria can modify their surfac... | LpxT-Dependent Phosphorylation of Lipid A in Escherichia coli Increases Resistance to Deoxycholate and Enhances Gut Colonization. | Frontiers in microbiology | microbiology | 990 | 44 |
Near infrared (NIR) spectroscopy combined with Monte Carlo uninformative variable elimination (MC-UVE) and nonlinear calibration methods employed to determine gossypol content in cottonseeds were investigated. The reference method was performed by high performance liquid chromatography coupled to an ultraviolet detecto... | Determination of gossypol content in cottonseeds by near infrared spectroscopy based on Monte Carlo uninformative variable elimination and nonlinear calibration methods. | Food chemistry | chemistry | 961 | 13 |
Among the existing multiplex genetically modified organism (GMO) detection methods, significant problems are highlighted, including amplification asymmetry of different targets, and the low detection throughput, which limits their capacity to meet the requirements of high-throughput analysis. To mitigate these challeng... | A 'turn-on' ultra-sensitive multiplex real-time fluorescent quantitative biosensor mediated by a universal primer and probe for the detection of genetically modified organisms. | Food chemistry | chemistry | 961 | 13 |
The δ 2 H and δ 18 O of 105 salmonids cultured in freshwater and seawater and from different regions were combined with linear discriminant analysis (LDA), k-nearest neighbor (KNN), and random forest (RF) to create discrimination models. To assess the stability of the discrimination models, seasonal variation in δ 2 H ... | Efficacy of using stable isotopes coupled with chemometrics to differentiate the production method and geographical origin of farmed salmonids. | Food chemistry | chemistry | 961 | 13 |
The effects of honeys from different floral origins on alcohol metabolism were compared, and the correlation between their chemical compositions and antialcholic effects was analyzed. The results demonstrated that the five types of investigated honeys from different floral origins had different effects on alcohol metab... | Anti-alcoholic effects of honeys from different floral origins and their correlation with honey chemical compositions. | Food chemistry | chemistry | 961 | 13 |
The purpose of this study was to construct a fusion model using probe-based and non-probe-based fluorescence spectroscopy and low-field nuclear magnetic resonance spectroscopy (Low-field NMR) for rapid quality evaluation of frying oil. Iron tetraphenylporphyrin (FeTPP) was selected as the probe to detect polar compound... | Intelligent evaluation of total polar compounds (TPC) content of frying oil based on fluorescence spectroscopy and low-field NMR. | Food chemistry | chemistry | 961 | 13 |
The potential of pulsed electric field (PEF) of different intensities (8, 18, and 28 kV/cm) on the conformation and gelation properties of myofibrillar proteins (MPs) extracted from pale, soft, and exudative-like (PSE-like) chicken meat was investigated. The results showed a positive correlation between gelation proper... | Effects of pulsed electric fields on the conformation and gelation properties of myofibrillar proteins isolated from pale, soft, exudative (PSE)-like chicken breast meat: A molecular dynamics study. | Food chemistry | chemistry | 961 | 13 |
Clinical trials show an inverse relationship between the consumption of antioxidant-rich tree nuts and the development of chronic diseases. This study examined antioxidant efficacy of U.S. pecans using a modified cellular antioxidant activity (CAA) assay with comparisons to data from in vitro antioxidant assays (hydrop... | Cellular evaluation of the antioxidant activity of U.S. Pecans [Carya illinoinensis (Wangenh.) K. Koch]. | Food chemistry | chemistry | 961 | 13 |
Durum wheat (Triticum turgidum ssp. durum) is widely grown in the Mediterranean area. The semolina obtained by this grain is used to prepare pasta, couscous, and baked products all over the world. The growing area affects the characteristics of Durum wheat; consequently, it is relevant to trace this product. The presen... | Multi-block classification of Italian semolina based on Near Infrared Spectroscopy (NIR) analysis and alveographic indices. | Food chemistry | chemistry | 961 | 13 |
Dry-cured loins elaborated from frozen (-20 °C/20 weeks)/thawed longissimus dorsi muscles (F) were compared with counterparts elaborated from fresh (unfrozen) muscles (UF) for the extent of protein oxidation (carbonylation and Schiff base formation) and their sensory profile (quantitative-descriptive analysis). All sam... | Effect of protein oxidation on the impaired quality of dry-cured loins produced from frozen pork meat. | Food chemistry | chemistry | 961 | 13 |
Rabbit is a healthy meat, with low allergenicity and excellent nutritional properties. The global popularity of rabbit meat makes it a target for food fraud. We present a LC-QTOF-MS/MS approach for detecting and identifying rabbit-specific peptide-markers from thermally processed meat products to differentiate rabbit f... | LC-QTOF-MS identification of rabbit-specific peptides for authenticating the species composition of meat products. | Food chemistry | chemistry | 961 | 13 |
Analytical chromatographic techniques for mycotoxins control are well established, but they often depend on costly immunoaffinity sample clean-up. Serum albumins, particularly that from bovine origin (BSA), have stable binding affinity towards some mycotoxins, and can be cheaper alternative receptors for sample clean-u... | BSA-based sample clean-up columns for ochratoxin A determination in wine: Method development and validation. | Food chemistry | chemistry | 961 | 13 |
Bovine milk lipids can be replaced with cheaper indigenous vegetable oils to produce milk alternatives with healthier saturated/unsaturated fat balance for those in areas where milk supply is poor or even absent. A wide range of vegetable oils can be used, but their impacts when blended with skimmed milk powder to form... | Chemometric studies of the effects of milk fat replacement with different proportions of vegetable oils in the formulation of fat-filled milk powders: Implications for quality assurance. | Food chemistry | chemistry | 961 | 13 |
The occurrence of deoxynivalenol, 3- and 15-deoxynivalenol and deoxynivalenol-3-glucoside in 84 durum wheat samples, from the Argentinean main growing area, was investigated during 2012/13 and 2013/14 using LC-MS/MS. Deoxynivalenol was found in all samples at concentrations varying between <LOQ (50μg/kg) and 9480μg/kg.... | Occurrence of deoxynivalenol and deoxynivalenol-3-glucoside in durum wheat from Argentina. | Food chemistry | chemistry | 961 | 13 |
Plasma is a medium of unbound negative and positive particles with the overall electrical charge being roughly zero. Non-thermal plasma processing is an emerging green technology with great potential to improve the quality and microbial safety of various food materials. Starch is a major component of many food products... | Plasma modification of starch. | Food chemistry | chemistry | 961 | 13 |
In this work, to improve the availability of the recognition sites of molecularly imprinted polymers (MIPs), ordered macroporous molecularly imprinted polymers (OMMIPs) were facilely prepared by grafting a quercetin-MIPs layer on the pore walls of the ordered macroporous thiol group functionalized silica. The pore stru... | Ordered macroporous molecularly imprinted polymers prepared by a surface imprinting method and their applications to the direct extraction of flavonoids from Gingko leaves. | Food chemistry | chemistry | 961 | 13 |
A highly specific competitive enzyme-linked immunosorbent assay (ELISA) protocol has been developed to identify and classify almond products based on differential proteomic analysis. We applied two-dimensional electrophoresis to compare the differences between almond and apricot kernels to search for almond-specific pr... | High-specificity quantification method for almond-by-products, based on differential proteomic analysis. | Food chemistry | chemistry | 961 | 13 |
Chelation of iron and zinc in wheat as phytates lowers their bio-accessibility. Steeping and germination (15 °C, 120 h) lowered phytate content from 0.96% to only 0.81% of initial dry matter. A multifactorial experiment in which (steeped/germinated) wheat was subjected to different time (2-24 h), temperature (20-80 °C)... | The impact of steeping, germination and hydrothermal processing of wheat (Triticum aestivum L.) grains on phytate hydrolysis and the distribution, speciation and bio-accessibility of iron and zinc elements. | Food chemistry | chemistry | 961 | 13 |
Rice bran wax (RBW) is a traditional plant based natural wax and an increasingly popular component in textiles, fruit coatings and cosmetics. Properties of RBW can be modified by acyglycerols, and the resulting products can possess features with great potential in different applications. In this study, RBW was interest... | Interesterification of rice bran wax and palm olein catalyzed by lipase: Crystallization behaviours and characterization. | Food chemistry | chemistry | 961 | 13 |
A new multiresidue method was developed for determination of 25 pesticide residues in red wine by gas chromatography coupled to mass spectrometry with a single run of 23.63 min. Samples were extracted from wine with solid phase extraction using Oasis HLB. Mixture of methanol and water was used for rinsing, while aceton... | Novel multiresidue method for determination of pesticides in red wine using gas chromatography-mass spectrometry and solid phase extraction. | Food chemistry | chemistry | 961 | 13 |
The antioxidant activities of polysaccharide from bitter gourd were studied. It was found that bitter gourd polysaccharide could significantly increase SOD and CAT contents in serum, liver and brain of mice, and reduce MDA levels in serum, liver and brain to a certain extent in vivo. So, bitter gourd polysaccharide sho... | The antioxidant activities in vivo of bitter gourd polysaccharide. | International journal of biological macromolecules | economics | 1,204 | 21 |
Fusarium head blight (FHB) disease caused by Fusarium graminearum is one of the most important diseases of wheat in humid and warm areas. This disease significantly reduces yield as well as seed quality. The aim of this work was to evaluate the possibility of control of FHB by chitosan (CS) and chitosan nanoparticles (... | Application of chitosan and chitosan nanoparticles for the control of Fusarium head blight of wheat (Fusarium graminearum) in vitro and greenhouse. | International journal of biological macromolecules | economics | 1,204 | 21 |
The crustacean shells of crabs and shrimps produces quantities of by-products, leading to seriously environmental pollution and human health problems during industrial processing, yet they turned into high-value useful products, such as chitin and chitosan. To prepare them under large-scale submerged fermentation level... | The preparation and characterization of chitin and chitosan under large-scale submerged fermentation level using shrimp by-products as substrate. | International journal of biological macromolecules | economics | 1,204 | 21 |
The large water holding capacity of Basil Seed (Ocimum basilicum L.) Mucilage (BSM) gives it potential to produce a valuable polymer for water holding applications such as wound dressing. The objective of this research was to prepare a natural-based antibacterial wound dressing from BSM by freeze-drying. Various conten... | Characterization of an antibacterial wound dressing from basil seed (Ocimum basilicum L.) mucilage-ZnO nanocomposite. | International journal of biological macromolecules | economics | 1,204 | 21 |
The objective of this study was to evaluate the effects of drying temperature (30, 50, 70, and 90 °C) and genotype (yellow floury corn, white floury corn, and yellow flint corn) on the morphology and technological and thermal properties of corn starch. The white and yellow genotypes with floury endosperm (soft) had sph... | Effects of drying temperature and genotype on morphology and technological, thermal, and pasting properties of corn starch. | International journal of biological macromolecules | economics | 1,204 | 21 |
Nanoparticles have been investigated as flagging tests for the sensitive DNA recognition that can be utilized as a part of field applications to defeat restrictions. Gold nanoparticles (AuNPs) have been widely utilized due to its optical property and capacity to get functionalized with a mixed bag of biomolecules. This... | A direct detection of human papillomavirus 16 genomic DNA using gold nanoprobes. | International journal of biological macromolecules | economics | 1,204 | 21 |
Dioscorea bulbifera or air potato has been used as a folk remedy to treat cancer. A mannose binding lectin from bulbils of D. bulbifera was purified in a single step by affinity chromatography on mucin coupled Sepharose 4B column, determined by its fine sugar specificity by glycan array analysis and studied for its cli... | Purification, characterization and biological significance of mannose binding lectin from Dioscorea bulbifera bulbils. | International journal of biological macromolecules | economics | 1,204 | 21 |
We present a facile synthesis of bovine serum albumin (BSA) conjugated low-dimensional ZnS nanocrystals. The experimental parameters such as effects of BSA concentration and precursor vol ratios of Zn:S on the formation of ZnS nanoparticles in BSA matrix were investigated. The ZnS crystalline sizes of 1.9, 1.8 and 1.6n... | Facile synthesis of bovine serum albumin conjugated low-dimensional ZnS nanocrystals. | International journal of biological macromolecules | economics | 1,204 | 21 |
Exopolysaccharides (EPS) are important bioproducts produced by some genera of lactic acid bacteria. EPS are famous for their shelf-life improving properties, techno-functional enhancing abilities in food and dairy industries, besides their beneficial health effects. Furthermore, exopolysaccharides have many prospective... | Contributions of exopolysaccharides from lactic acid bacteria as biotechnological tools in food, pharmaceutical, and medical applications. | International journal of biological macromolecules | economics | 1,204 | 21 |
To selectively target telomeric G-quadruplex (G4) DNA, monomeric and dimeric naphthalene diimides (NDIs) were investigated as binders of multimeric G4 structures able to discriminate duplex DNA. These NDIs were analysed by the affinity chromatography-based screening G4-CPG (G-quadruplex on Controlled Pore Glass), using... | On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model. | International journal of biological macromolecules | economics | 1,204 | 21 |
Epidermal growth factor (EGF) is a local growth factor that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. EGF and EGFR are involved in many aspects of the development of carcinomas. Because EGFR has been found to be over-expressed in many tumors of epithelial origin, it is ... | Development of a human epidermal growth factor derivative with EGFR-blocking and depleted biological activities: A comparative in vitro study using EGFR-positive breast cancer cells. | International journal of biological macromolecules | economics | 1,204 | 21 |
This study investigated the optimization of thermal, functional and rheological properties of Ethyl Cellulose (EC)-based oleogel considering different concentrations of Behenic Acid (BA) and stability of water in oleogel (w/og) emulsions. The results showed that the combination of EC and BA improved the oleogel propert... | Development of behenic acid-ethyl cellulose oleogel stabilized Pickering emulsions as low calorie fat replacer. | International journal of biological macromolecules | economics | 1,204 | 21 |
Advanced melanoma patients that are not included in common genetic classificatory groups lack effective and safe therapeutic options. Chemotherapy and immunotherapy show unsatisfactory results and devastating adverse effects for these called triple wild-type patients. New approaches exploring the intrinsic antitumor pr... | Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas. | International journal of biological macromolecules | economics | 1,204 | 21 |
A novel chitinase (P1724) was discovered from a Qinghai-Tibetan plateau microbial metagenome. P1724 contains two GH18 family catalytic domains and is phylogenetically distant from any of the chitinases studied. P1724 and its truncated versions, P1724(∆cGH18) and P1724(∆nGH18), were produced in Escherichia coli and char... | The discovery and characterization of a novel chitinase with dual catalytic domains from a Qinghai-Tibetan Plateau wetland soil metagenome. | International journal of biological macromolecules | economics | 1,204 | 21 |
The exposed hydrophobic patches of protein are widely detected through the binding by the fluorescent probes such as 1-anilino-8-naphthalene sulfonate (ANS), Nile Red (NR) and 1-(N-phenylamino) naphthalene, N-(1-Naphthyl) aniline (1NPN). Interestingly, at pH4, where the Toxoplasma gondii Ferredoxin-NADP(+) reductase (T... | New insight on 8-anilino-1-naphthalene sulfonic acid interaction with TgFNR for hydrophobic exposure analysis. | International journal of biological macromolecules | economics | 1,204 | 21 |
We develop a robust micro-patterned double-layer film that can adhere firmly to the tissue and provide a sustained release of ascorbic acid (AA) for corneal regeneration. This double-layer film consists of a AA reservoir sodium alginate (SA) adhesive and an anisotropic layer made of micro-patterned silk nanofibrils (SN... | Robust and double-layer micro-patterned bioadhesive based on silk nanofibril/GelMA-alginate for stroma tissue engineering. | International journal of biological macromolecules | economics | 1,204 | 21 |
We report the preparation of both control chitosan and magnetic chitosan beads as biosorbents using chitosan as matrix and magnetite (Fe 3 O 4 ) nanoparticles as reinforcement followed by detailed advanced characterization. The batch trials were performed to study the adsorption kinetics of biosorbents by removing As (... | Development of sustainable magnetic chitosan biosorbent beads for kinetic remediation of arsenic contaminated water. | International journal of biological macromolecules | economics | 1,204 | 21 |
Dendritic cells (DCs) are the key regulators of immune responses. In this study, the effect of an exopolysaccharide (EPS) from the culture broth of Trichoderma pseudokoningii on the phenotypic and functional maturation of murine DCs and its underlying molecular mechanisms were investigated. It showed that EPS induced t... | Exopolysaccharide from Trichoderma pseudokoningii promotes maturation of murine dendritic cells. | International journal of biological macromolecules | economics | 1,204 | 21 |
Fibronectin type-II (FnII) family proteins are the major proteins in many mammalian species including bull, horse and pig. In the present study, a major FnII protein has been identified and isolated from donkey (Equus hemionus) seminal plasma, which we refer to as Donkey Seminal Plasma protein-1 (DSP-1). The amino acid... | Purification, molecular characterization and ligand binding properties of the major donkey seminal plasma protein DSP-1. | International journal of biological macromolecules | economics | 1,204 | 21 |
Polymer electrolyte membrane fuel cells represent a next-generation power supply technology that may be used in a diverse range of applications. Towards this end, the rational design and engineering of functional nanomaterials as low-cost, high-performance catalysts is of critical significance in the wide-spread commer... | Impacts of interfacial charge transfer on nanoparticle electrocatalytic activity towards oxygen reduction. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Interfacial reaction and transport processes contribute crucially to the overall performance and impedance of electrochemical systems. The influence of the electrochemical double layer and the interfacial reactions on the impedance of lithium intercalation batteries is investigated with a modeling approach. Our generic... | The electrochemical double layer and its impedance behavior in lithium-ion batteries. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
A model of phosphorylated and ATP-containing B-Raf protein kinase is needed as a tool for the structure-based design of new allosteric inhibitors, since no crystal structure of such a system has been resolved. Here, we present the development of such a model as well as a thorough analysis of its structural features. Th... | Development of the first model of a phosphorylated, ATP/Mg2+-containing B-Raf monomer by molecular dynamics simulations: a tool for structure-based design. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Cubane-type Mo 3 S 4 cluster hydrides decorated with phosphine ligands are active catalysts for the transfer hydrogenation of nitroarenes to aniline derivatives in the presence of formic acid (HCOOH) and triethylamine (Et 3 N). The process is highly selective and most of the cluster species involved in the catalytic cy... | On the catalytic transfer hydrogenation of nitroarenes by a cubane-type Mo3S4 cluster hydride: disentangling the nature of the reaction mechanism. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Proton conduction in alkali metal ion-exchanged porous ionic crystals A 2 [Cr 3 O(OOCH) 6 (etpy) 3 ] 2 [α-SiW 12 O 40 ]·nH 2 O [I-A + ] (A = Li, Na, K, Cs, etpy = 4-ethylpyridine) is investigated. Single crystal and powder X-ray diffraction measurements show that I-A + possesses analogous one-dimensional channels where... | Proton conduction in alkali metal ion-exchanged porous ionic crystals. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
X-ray reflectivity and transmission electron microscopy (TEM) were used to characterize the morphological changes in thin film electrodes with alternating Ni and NiO layers during lithiation as a function of the Ni buffer layer thickness. Complete lithiation of the active NiO layers occurs only when the thickness of th... | Lithiation of multilayer Ni/NiO electrodes: criticality of nickel layer thicknesses on conversion reaction kinetics. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Graphene is widely used in numerous scientific fields including physics, chemistry and materials science due to its exceptional electrical, thermal, optical and mechanical properties. However, the poor solubility/dispersibility strongly limits the practical applications of graphene. In this work, hydroxypropyl hydrazin... | One-step reducing and dispersing graphene oxide via hydroxypropyl hydrazine and its applications in Cu2+ removal. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Graphitic carbon nitride (g-C 3 N 4 ) synthesised from a urea precursor is an excellent CO 2 reduction photocatalyst using [Co(bpy) n ] 2+ as a co-catalyst. A five-fold increase in activity for the highly polymerised urea derived g-C 3 N 4 is achieved compared to alternative precursors. Transient absorption, time-resol... | Photochemical CO2 reduction using structurally controlled g-C3N4. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
The indirect method for the construction of quantum mechanics (QM)/molecular mechanics (MM) free energy landscapes provides a cheaper alternative for free energy simulations at the QM level. The indirect method features a direct calculation of the free energy profile with a computationally efficient but less accurate H... | BAR-based multi-dimensional nonequilibrium pulling for indirect construction of QM/MM free energy landscapes: from semi-empirical to ab initio. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
The OH initiated oxidation of HNO3 in the UT/LS plays an important role in controlling the O3 budget, removing HOx radicals whilst driving NOx/y partitioning chemistry by yielding NO3 radicals: OH + HNO3 → H2O + NO3. In this paper, k1(T, P) was measured using OH (A ← X) Laser Induced Fluorescence (LIF) and the data was... | Reaction kinetics of OH + HNO3 under conditions relevant to the upper troposphere/lower stratosphere. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Aluminum monochloride (AlCl) has been proposed as a promising candidate for laser cooling to ultracold temperatures, and recent spectroscopy results support this prediction. It is challenging to produce large numbers of AlCl molecules because it is a highly reactive open-shell molecule and must be generated in situ . H... | Optimizing pulsed-laser ablation production of AlCl molecules for laser cooling. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
The dynamics of the magnetic moment reversal is studied for ErFeO3 and NdFeO3 single crystals. The reversal occurs at 41 and 5.1 K for ErFeO3 and NdFeO3, respectively, at a field of 300 Oe. The dynamics of the magnetization reversal process depends on the temperature at which the reversal occurs. The reversal is abrupt... | Magnetization reversal on different time-scales for ErFeO3 and NdFeO3 single crystals. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
From the analysis of UV/Vis absorption spectra, emission and excitation emission spectra of solutions of all-trans-1,6-diphenyl-1,3,5-hexatriene (DPH) in carbon disulfide (CS 2 ) within a wide range of temperatures, we can conclude that these spectra do not support the inversion of excited electronic states in DPH by a... | Inversion of the 11Bu and 21Ag electronic states of all-trans-1,6-diphenyl-1,3,5-hexatriene in carbon disulfide. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
The consideration of polar interactions is of vital importance for the development of predictive and accurate thermodynamic models for polar fluids, as they govern most of their thermodynamic properties, making them highly non-ideal fluids. We present here for the first time the extension of the soft-SAFT equation of s... | Polar soft-SAFT: theory and comparison with molecular simulations and experimental data of pure polar fluids. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
Although general porous materials have a low dielectric constant, their uncontrollable opened porous structure results in high dielectric loss and poor barrier properties, thus limiting their application as interconnect dielectrics. In this study, polymeric nanoporous materials with well-controlled closed pores were pr... | Preparation and unique dielectric properties of nanoporous materials with well-controlled closed-nanopores. | Physical chemistry chemical physics : PCCP | chemistry | 2,148 | 13 |
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