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scPerturb-derived model-ready H5AD

This directory contains 252 human cell-level derivatives prepared from the scPerturb collection: 23 gene-perturbation units and 229 chemical-perturbation units. It does not contain the upstream raw downloads.

modality units cells reference effect
genepert 23 3,468,800 218,422 3,250,378
chempert 229 1,306,002 179,106 1,126,896

For every file, X is per-cell CP10K natural log1p, confirmed raw UMI counts are in layers["counts"], and the independently trained 30-dimensional scVI representation is in obsm["X_scVI"]. Control/reference selection must use obs["is_reference"]; vehicle/DMSO must not be reinterpreted as untreated or time zero.

The on-disk directory name scPeturb is a retained historical spelling. The machine-readable source label and center paths use scPerturb; paths are case-sensitive. Always obtain paths from ../manifest/TRAINING_UNITS.tsv.

These are processed/model-ready derivatives, not raw source files. Read ../README.en.md, ../DATA_DICTIONARY.md, and ../USAGE.md before use. The source release, original-study citations, licenses, and redistribution status must be taken from the Stage 1 source-provenance table; do not infer a data license from the scPerturb software repository.

The audited redistribution basis for these files is the scPerturb v1.4 dataset record (10.5281/zenodo.13350497), which applies CC BY 4.0. Public release must attribute scPerturb and each original study, link the license, and identify the CellClip modifications described in ../PROCESSING.md.