id stringlengths 32 40 | source stringclasses 46
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ac39a2f995f1b55c4a5af127f3bd15cb2072ad88 | wikidoc | ANO1 | ANO1
Anoctamin-1 (ANO1) also known as Transmembrane member 16A (TMEM16A) is a protein that, in humans, is encoded by the ANO1 gene. Anoctamin-1 is a voltage-sensitive calcium-activated chloride channel that is expressed in smooth muscle and epithelial cells; it is highly expressed in human interstitial cells of Cajal (... | ANO1
Anoctamin-1 (ANO1) also known as Transmembrane member 16A (TMEM16A) is a protein that, in humans, is encoded by the ANO1 gene.[1][2] Anoctamin-1 is a voltage-sensitive calcium-activated chloride channel that is expressed in smooth muscle and epithelial cells;[3] it is highly expressed in human interstitial cells ... | https://www.wikidoc.org/index.php/ANO1 | |
1b3aa69b83d864faaf131220f9803c2d5ab19ff2 | wikidoc | BUB3 | BUB3
Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.
Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the irreversi... | BUB3
Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.[1][2]
Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the ir... | https://www.wikidoc.org/index.php/BUB3 | |
b607626a54fae532e88c1527f8f61e9c34c090a9 | wikidoc | CBR1 | CBR1
Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene. The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones,... | CBR1
Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene.[1][2][3] The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as... | https://www.wikidoc.org/index.php/CBR1 | |
2a8442b5a545394b6286a647adec33a6532ece5d | wikidoc | CD44 | CD44
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11. CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lymphocyte... | CD44
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11.[1] CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lympho... | https://www.wikidoc.org/index.php/CD44 | |
5670057548543b8ea609f9054cc79a681b22f85e | wikidoc | CD61 | CD61
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes.
# Structure and function
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a be... | CD61
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.[1] CD61 is a cluster of differentiation found on thrombocytes.[2]
# Structure and function
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain a... | https://www.wikidoc.org/index.php/CD61 | |
e11e375f0746971fa7e1c9de419f8617bb2507fb | wikidoc | CHUK | CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans is encoded by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription fact... | CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-α) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that in humans is encoded by the CHUK gene.[1] IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription ... | https://www.wikidoc.org/index.php/CHUK | |
8a5b6dffea68360caad64ed70f9971c4b17ff2e2 | wikidoc | Cyst | Cyst
# Overview
A cyst is a closed sac having a distinct membrane and division on the nearby tissue. It may contain air, fluid, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once formed, the cyst will remain in the tissue but can be removed by surgery or resolve by taking medications.
A... | Cyst
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
# Overview
A cyst is a closed sac having a distinct membrane and division on the nearby tissue. It may contain air, fluid, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once fo... | https://www.wikidoc.org/index.php/Cyst | |
c2d10392837c3889fa586630474d91ca6288833e | wikidoc | Twin | Twin
Twins are a form of multiple birth in which the mother gives birth to two offspring from the same pregnancy, either of the same or opposite sex.
The general term for more than one offspring from the same pregnancy is multiples, for example triplets refers to cases of three offspring from the same pregnancy. A fet... | Twin
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]
Twins are a form of multiple birth in which the mother gives birth to two offspring from the same pregnancy, either of the same or opposite sex.
The general term for more than one offspring from the same pregnancy is multiples, for example triplets refers to case... | https://www.wikidoc.org/index.php/Dizygotic_twins | |
c9cc104abf73e5600be2c8aca3251931a292c08f | wikidoc | FADD | FADD
Fas-associated protein with death domain (FADD), also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans.
FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-i... | FADD
Fas-associated protein with death domain (FADD), also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans.[1]
FADD is an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the dea... | https://www.wikidoc.org/index.php/FADD | |
049821672806e8d3fcb126e937cacb2280b0c3ee | wikidoc | FMR1 | FMR1
FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP. This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function. Mutations of this gene can lead to fragile X syndrome,... | FMR1
FMR1 (fragile X mental retardation 1) is a human gene[1] that codes for a protein called fragile X mental retardation protein, or FMRP.[2] This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function. Mutations of this gene can lead to fragile X sy... | https://www.wikidoc.org/index.php/FMR1 | |
453fda6413b39c20c4181529767de7e85c683910 | wikidoc | GPER | GPER
G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells.
# Discovery
T... | GPER
G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene.[1] GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells.
# Discove... | https://www.wikidoc.org/index.php/GPER | |
bc12b00191390f86d41a6f5a052da667e03291f1 | wikidoc | HeLa | HeLa
A HeLa cell (also Hela or hela cell) is an immortal cell line used in medical research. The cell line was derived from cervical cancer cells taken from Henrietta Lacks, who died from her cancer in 1951.
# George Otto Gey and Henrietta Lacks
The cells were propagated by George Otto Gey without Lacks' knowledge or... | HeLa
A HeLa cell (also Hela or hela cell) is an immortal cell line used in medical research. The cell line was derived from cervical cancer cells taken from Henrietta Lacks, who died from her cancer in 1951.
# George Otto Gey and Henrietta Lacks
The cells were propagated by George Otto Gey without Lacks' knowledge o... | https://www.wikidoc.org/index.php/HeLa | |
166611e183b78f127da2eb0d99beb98dfd93c9eb | wikidoc | KAT5 | KAT5
Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. It is also commonly identified as TIP60.
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important rol... | KAT5
Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene.[1][2] It is also commonly identified as TIP60.
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play import... | https://www.wikidoc.org/index.php/KAT5 | |
279f294c95544f4689344129e48fa91215be43f3 | wikidoc | KLF4 | KLF4
Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996. KLF4 is a member of the KLF family of transcription factors, which belongs to the relatively large family of SP1-like transcription factors. KLF4 is involved in the reg... | KLF4
Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996.[1] KLF4 is a member of the KLF family of transcription factors, which belongs to the relatively large family of SP1-like transcription factors.[2][3][4] KLF4 is involv... | https://www.wikidoc.org/index.php/KLF4 | |
defa2865ffb8a84a63292ec5605d872eac7caa73 | wikidoc | MCM8 | MCM8
DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by t... | MCM8
DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene.[1][2]
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex form... | https://www.wikidoc.org/index.php/MCM8 | |
6c5c67b6a4a2f7945a3be8b0a6c3d8a5cc14bb2e | wikidoc | MDC1 | MDC1
Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene located on the short arm (p) of chromosome 6. MDC1 protein is a regulator of the Intra-S phase and the G2/M cell cycle checkpoints and recruits repair proteins to the site of DNA damage. It is i... | MDC1
Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene[1][2][3] located on the short arm (p) of chromosome 6. MDC1 protein is a regulator of the Intra-S phase and the G2/M cell cycle checkpoints and recruits repair proteins to the site of DNA damag... | https://www.wikidoc.org/index.php/MDC1 | |
20a64e7aa8db933eaba0f91d9f19d3f56aa997ee | wikidoc | MMP7 | MMP7
Matrilysin also known as matrix metalloproteinase-7 (MMP-7), pump-1 protease (PUMP-1), or uterine metalloproteinase is an enzyme in humans that is encoded by the MMP7 gene.
Matrilysin was discovered by Sellers and Woessner in the uterus of the rat in 1988. The complementary DNA (cDNA) of human MMP7 was isolated i... | MMP7
Matrilysin also known as matrix metalloproteinase-7 (MMP-7), pump-1 protease (PUMP-1), or uterine metalloproteinase is an enzyme in humans that is encoded by the MMP7 gene.[1]
Matrilysin was discovered by Sellers and Woessner in the uterus of the rat in 1988.[2] The complementary DNA (cDNA) of human MMP7 was iso... | https://www.wikidoc.org/index.php/MMP7 | |
949e4076978f67f47d55e67a9f3d211a0d5c8b36 | wikidoc | MSH6 | MSH6
MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. It is the homologue of the human "G/T binding protein," (GTBP) also called p160 or hMSH6 (human MSH6). The MSH6 protein is a member of the Mutator S (MutS) family of proteins that are inv... | MSH6
MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. It is the homologue of the human "G/T binding protein," (GTBP) also called p160 or hMSH6 (human MSH6). The MSH6 protein is a member of the Mutator S (MutS) family of proteins that are in... | https://www.wikidoc.org/index.php/MSH6 | |
7dda57e930a55e46c111770c5ae8698825ce839c | wikidoc | MSMB | MSMB
Beta-microseminoprotein is a protein that in humans is encoded by the MSMB gene. For historical reasons, the scientific literature may also refer to this protein as Prostate secretory protein 94 (PSP94), microseminoprotein (MSP), microseminoprotein-beta (MSMB), beta-inhibitin, prostatic inhibin peptide (PIP), and ... | MSMB
Beta-microseminoprotein is a protein that in humans is encoded by the MSMB gene.[1][2] For historical reasons, the scientific literature may also refer to this protein as Prostate secretory protein 94 (PSP94), microseminoprotein (MSP), microseminoprotein-beta (MSMB), beta-inhibitin, prostatic inhibin peptide (PIP... | https://www.wikidoc.org/index.php/MSMB | |
5193008feb20cb2b46b705cc67c973d4f5a37221 | wikidoc | MUC1 | MUC1
Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and seve... | MUC1
Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans.[1] MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and ... | https://www.wikidoc.org/index.php/MUC1 | |
64431ba98097b836822502a9d4aada54b1d5054b | wikidoc | MYH9 | MYH9
Myosin-9 also known as myosin, heavy chain 9, non-muscle or non-muscle myosin heavy chain IIa (NMMHC-IIA) is a protein which in humans is encoded by the MYH9 gene.
Non-muscle myosin IIA (NM IIA) is expressed in most cells and tissues where it participates in a variety of processes requiring contractile force, such... | MYH9
Myosin-9 also known as myosin, heavy chain 9, non-muscle or non-muscle myosin heavy chain IIa (NMMHC-IIA) is a protein which in humans is encoded by the MYH9 gene.[1][2]
Non-muscle myosin IIA (NM IIA) is expressed in most cells and tissues where it participates in a variety of processes requiring contractile forc... | https://www.wikidoc.org/index.php/MYH9 | |
70bc8a764a40dae299691afcce26a359c5a983f7 | wikidoc | OSR1 | OSR1
Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene. The OSR1 and OSR2 transcription factors participate in the normal development of body parts such as the kidney.
Protein odd-skipped related 1 is a zinc-finger transcription factor that, in humans, is encoded by the ... | OSR1
Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene.[1][2][3] The OSR1 and OSR2 transcription factors participate in the normal development of body parts such as the kidney.[4]
Protein odd-skipped related 1 is a zinc-finger transcription factor that, in humans, is en... | https://www.wikidoc.org/index.php/OSR1 | |
55b05a0b1f501ebcc26486d4d6064ae81895419b | wikidoc | PAX8 | PAX8
Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene.
# Function
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type home... | PAX8
Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene.[1]
# Function
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type ... | https://www.wikidoc.org/index.php/PAX8 | |
532294dcc9eee4a6d5b36098e6fe5c462baa1c96 | wikidoc | PDPN | PDPN
Podoplanin is a protein that in humans is encoded by the "PDPN" gene.
# Structure and function
Podoplanin is a mucin-type protein with a mass of 36- to 43-kDa. It is relatively well conserved between species, with homologues in humans, mice, rats, dogs and hamsters.
This gene encodes a type-I, integral membrane, ... | PDPN
Podoplanin is a protein that in humans is encoded by the "PDPN" gene.[1][2][3]
# Structure and function
Podoplanin is a mucin-type protein with a mass of 36- to 43-kDa. It is relatively well conserved between species, with homologues in humans, mice, rats, dogs and hamsters.[4]
This gene encodes a type-I, integr... | https://www.wikidoc.org/index.php/PDPN | |
d0a30dcffe7f15fb7aa3673de2069bf54c8c316a | wikidoc | PEPD | PEPD
Xaa-Pro dipeptidase, also known as prolidase, is an enzyme that in humans is encoded by the PEPD gene.
# Function
Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism because of th... | PEPD
Xaa-Pro dipeptidase, also known as prolidase, is an enzyme that in humans is encoded by the PEPD gene.[1][2][3]
# Function
Xaa-Pro dipeptidase is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus (but not Pro-Pro). It is important in collagen metabolism bec... | https://www.wikidoc.org/index.php/PEPD | |
29586e3cff0954e8dc280d5e9c8b3f282d8009e1 | wikidoc | RBP1 | RBP1
Retinol binding protein 1, cellular, also known as RBP1, is a protein that in humans is encoded by the RBP1 gene.
# Function
RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growt... | RBP1
Retinol binding protein 1, cellular, also known as RBP1, is a protein that in humans is encoded by the RBP1 gene.[1][2][3]
# Function
RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary... | https://www.wikidoc.org/index.php/RBP1 | |
05d6c2e8a08fd2a8efcbed36b52e1e3f4c83bdc4 | wikidoc | RELA | RELA
Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene.
RELA, also known as p65, is a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor comple... | RELA
Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene.[1]
RELA, also known as p65, is a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor co... | https://www.wikidoc.org/index.php/RELA | |
8c07fe7965263c561a260be8ed16ac670554d809 | wikidoc | RPN2 | RPN2
Dolichyl-diphosphooligosaccharide—protein glycosyltransferase subunit 2, also called ribophorin ǁ is an enzyme that in humans is encoded by the RPN2 gene.
# Function
This gene encodes a type I integral ribophorin membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-o... | RPN2
Dolichyl-diphosphooligosaccharide—protein glycosyltransferase subunit 2, also called ribophorin ǁ is an enzyme that in humans is encoded by the RPN2 gene.[1]
# Function
This gene encodes a type I integral ribophorin membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an... | https://www.wikidoc.org/index.php/RPN2 | |
ca3c4e1bca58b82f2691dedb4e7e4ef553cb3290 | wikidoc | RTL6 | RTL6
Retrotransposon Gag Like 6 is a protein encoded by the RTL6 gene in humans. RTL6 is a member of the Mart family of genes, which are related to Sushi-like retrotransposons and were derived from fish and amphibians. The RTL6 protein is localized to the nucleus and has a predicted leucine zipper motif that is known t... | RTL6
Retrotransposon Gag Like 6 is a protein encoded by the RTL6 gene in humans.[1] RTL6 is a member of the Mart family of genes, which are related to Sushi-like retrotransposons and were derived from fish and amphibians.[2] The RTL6 protein is localized to the nucleus and has a predicted leucine zipper motif that is ... | https://www.wikidoc.org/index.php/RTL6 | |
f16764fbc60f7e5ccdb78beb8b67d9ab6a47b183 | wikidoc | SOX2 | SOX2
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. Sox2 has a critical role in maintenance of embryonic and neural stem cells.
Sox2 is a member of the Sox family of transcript... | SOX2
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. Sox2 has a critical role in maintenance of embryonic and neural stem cells.[1]
Sox2 is a member of the Sox family of transc... | https://www.wikidoc.org/index.php/SOX2 | |
333fc3f29c0ecd019d3149d0d8daee9ba64d14a3 | wikidoc | SOX4 | SOX4
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.
# Function
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein m... | SOX4
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.[1][2][3]
# Function
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded... | https://www.wikidoc.org/index.php/SOX4 | |
3087a3dc5233e6678b43816da441c49eaf4bdddd | wikidoc | ST14 | ST14
Suppressor of tumorigenicity 14 protein, also known as matriptase, is a protein that in humans is encoded by the ST14 gene. ST14 orthologs have been identified in most mammals for which complete genome data are available.
# Function
Matriptase is an epithelial-derived, integral membrane serine protease. This prot... | ST14
Suppressor of tumorigenicity 14 protein, also known as matriptase, is a protein that in humans is encoded by the ST14 gene.[1] ST14 orthologs[2] have been identified in most mammals for which complete genome data are available.
# Function
Matriptase is an epithelial-derived, integral membrane serine protease. Th... | https://www.wikidoc.org/index.php/ST14 | |
21a4da2587cedddef2f3de54772fc4ebdc3991a1 | wikidoc | TLR4 | TLR4
Toll-like receptor 4 is a protein that in humans is encoded by the TLR4 gene. TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine producti... | TLR4
Toll-like receptor 4 is a protein that in humans is encoded by the TLR4 gene. TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine product... | https://www.wikidoc.org/index.php/TLR4 | |
7209f46e5f42c71dd0c24c8b80b3c841a6f72846 | wikidoc | TLR5 | TLR5
Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria. Its has been shown to be involved in the onset of many diseases, which includes In... | TLR5
Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene.[1] It is a member of the toll-like receptor (TLR) family. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria.[2] Its has been shown to be involved in the onset of many diseases, which incl... | https://www.wikidoc.org/index.php/TLR5 | |
ff5a41216694922a675c53eaa6d91adf27f767ba | wikidoc | TLR9 | TLR9
Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289). It is a member of the toll-like receptor (TLR) family. TLR9 is an important receptor expressed in immune system cells including dendritic cells, macrophages, natura... | TLR9
Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene.[1] TLR9 has also been designated as CD289 (cluster of differentiation 289). It is a member of the toll-like receptor (TLR) family. TLR9 is an important receptor expressed in immune system cells including dendritic cells, macrophages, na... | https://www.wikidoc.org/index.php/TLR9 | |
206f814685e12da823424649ba70890e7896e82e | wikidoc | TMC8 | TMC8
Transmembrane channel-like 8 is a protein which in humans is encoded by the TMC8 gene.
# Function
The protein encoded by this gene is an integral membrane protein that localize to the endoplasmic reticulum and is predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with... | TMC8
Transmembrane channel-like 8 is a protein which in humans is encoded by the TMC8 gene.[1][2]
# Function
The protein encoded by this gene is an integral membrane protein that localize to the endoplasmic reticulum and is predicted to form transmembrane channels. This gene encodes a transmembrane channel-like prote... | https://www.wikidoc.org/index.php/TMC8 | |
36016b2bd106251cfc8b9b053013dc25ad0bcc40 | wikidoc | TP53 | TP53
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homo... | TP53
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Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53... | https://www.wikidoc.org/index.php/TP53 | |
fd1b198a4bf4c7fd632f1facde5bcd7602a2de7e | wikidoc | TP63 | TP63
Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 (also known as the p63) gene.
The TP63 gene was discovered 20 years after the discovery of the p53 tumor suppressor gene and along with p73 constitutes the p53 gene f... | TP63
Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 (also known as the p63) gene.[1][2][3][4]
The TP63 gene was discovered 20 years after the discovery of the p53 tumor suppressor gene and along with p73 constitutes t... | https://www.wikidoc.org/index.php/TP63 | |
5af7ac3d773d2113661806f3015adc3e1da95179 | wikidoc | TSC2 | TSC2
Tuberous Sclerosis Complex 2 (TSC2), also known as Tuberin, is a protein that in humans is encoded by the TSC2 gene.
# Function
Mutations in this gene lead to tuberous sclerosis. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. Hamartin coded by the gene TSC1 functi... | TSC2
Tuberous Sclerosis Complex 2 (TSC2), also known as Tuberin, is a protein that in humans is encoded by the TSC2 gene.
# Function
Mutations in this gene lead to tuberous sclerosis. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. Hamartin coded by the gene TSC1 funct... | https://www.wikidoc.org/index.php/TSC2 | |
06355ac084687fdbe7047d1846394bd264d90647 | wikidoc | UTF1 | UTF1
Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene.
UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is loca... | UTF1
Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene.
[1] UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells.[2] Its expression is rapidly reduced upon differentiation. UTF1 protein ... | https://www.wikidoc.org/index.php/UTF1 | |
0ba2a0f1558375c18cbd9d78a74d822ecf447924 | wikidoc | WNT6 | WNT6
Wingless-type MMTV integration site family, member 6, also known as WNT6, is a human gene.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate... | WNT6
Wingless-type MMTV integration site family, member 6, also known as WNT6, is a human gene.[1][2]
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of ce... | https://www.wikidoc.org/index.php/WNT6 | |
18edafebc8848bc1a5615ecbe428b8558b00a0c2 | wikidoc | Myc | Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc, l-myc, and n-myc. c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
In cance... | Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc, l-myc, and n-myc. c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
In canc... | https://www.wikidoc.org/index.php/C-myc | |
a0003305819d3939037cfd749cbb7df5df070852 | wikidoc | FYN | FYN
Proto-oncogene tyrosine-protein kinase Fyn (p59-FYN, Slk, Syn, MGC45350, Gene ID 2534) is an enzyme that in humans is encoded by the FYN gene.
Fyn is a 59-kDa member of the Src family of kinases typically associated with T-cell and neuronal signaling in development and normal cell physiology. Disruptions in these s... | FYN
Proto-oncogene tyrosine-protein kinase Fyn (p59-FYN, Slk, Syn, MGC45350, Gene ID 2534)[1] is an enzyme that in humans is encoded by the FYN gene.[2]
Fyn is a 59-kDa member of the Src family of kinases typically associated with T-cell and neuronal signaling in development and normal cell physiology. Disruptions in ... | https://www.wikidoc.org/index.php/FYN | |
89022ae8b258b564e0bebdb65be822926fc93dc3 | wikidoc | ID4 | ID4
ID4 is a protein coding gene. In humans, it encodes for the protein known as DNA-binding protein inhibitor ID-4.
This protein is known to be involved in the regulation of many cellular processes during both prenatal development and tumorigenesis. This is inclusive of embryonic cellular growth, senescence, cellula... | ID4
ID4 is a protein coding gene. In humans, it encodes for the protein known as DNA-binding protein inhibitor ID-4.[1][2]
This protein is known to be involved in the regulation of many cellular processes during both prenatal development and tumorigenesis. This is inclusive of embryonic cellular growth, senescence, ... | https://www.wikidoc.org/index.php/ID4 | |
41fc2283847faa66029f49c7eada2fbdcb4db042 | wikidoc | MCL | MCL
What are you looking for?
- Johnie McL disease, a synonym for Hurler's syndrome
- Mantle cell lymphoma, a subtype of B-cell lymphoma
- Mast cell leukemia, an aggressive subtype of acute myeloid leukemia
- Medial collateral ligament, one of many ligaments of the knee
- Midclavicular line
- Mucocutaneous leishmaniasi... | MCL
What are you looking for?
- Johnie McL disease, a synonym for Hurler's syndrome
- Mantle cell lymphoma, a subtype of B-cell lymphoma
- Mast cell leukemia, an aggressive subtype of acute myeloid leukemia
- Medial collateral ligament, one of many ligaments of the knee
- Midclavicular line
- Mucocutaneous leishmanias... | https://www.wikidoc.org/index.php/MCL | |
1cb886dcf85d594e1726408b17e59bc5d69be583 | wikidoc | p16 | p16
p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor 1 and as several other synonyms), is a tumor suppressor protein, that in humans is encoded by the CDKN2A gene. p16 plays an important role in cell cycle regulation by decelerating the cell's progression from G1 phase to S p... | p16
p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor 1 and as several other synonyms), is a tumor suppressor protein, that in humans is encoded by the CDKN2A gene.[1][2][3] p16 plays an important role in cell cycle regulation by decelerating the cell's progression from G1 ph... | https://www.wikidoc.org/index.php/P16 | |
cc7ed209c4f2c11b404c6e6d9e73158869d24472 | wikidoc | p53 | p53
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Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform... | p53
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Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isofor... | https://www.wikidoc.org/index.php/P53 | |
393e291fc33539df91eafbfd620c23e9df501a25 | wikidoc | SnS | SnS
- -itis
- Aaron's sign
- Abadie's symptom
- Abdominal angina
- Abdominal angina (patient information)
- Abdominal bruit
- Abdominal distension
- Abdominal enlargement
- Abdominal guarding
- Abdominal mass
- Abdominal pain
- Abnormal posturing
- Abnormalities in erythrocyte morphology
- Absence seizure
- Acanthosis ... | SnS
- -itis
- Aaron's sign
- Abadie's symptom
- Abdominal angina
- Abdominal angina (patient information)
- Abdominal bruit
- Abdominal distension
- Abdominal enlargement
- Abdominal guarding
- Abdominal mass
- Abdominal pain
- Abnormal posturing
- Abnormalities in erythrocyte morphology
- Absence seizure
- Acanthosis... | https://www.wikidoc.org/index.php/SnS | |
4c3dbd1bf28e2a2c036c2690b628f18ef0d33a27 | wikidoc | WT1 | WT1
Wilms tumor protein is a protein that in humans is encoded by the WT1 gene on chromosome 11p.
# Function
This gene encodes a transcription factor that contains four zinc finger motifs at the C-terminus and a proline / glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal devel... | WT1
Wilms tumor protein is a protein that in humans is encoded by the WT1 gene on chromosome 11p.[1][2][3][4]
# Function
This gene encodes a transcription factor that contains four zinc finger motifs at the C-terminus and a proline / glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the... | https://www.wikidoc.org/index.php/WT1 |
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