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Multiple Sclerosis Research group leader Prof. Remes has a wide expertise in clinical drug trials of multiples sclerosis and she is the chair of Current Care Guidelines for multiple sclerosis in Finland. She is also the Finnish representative of ECTRIMS council. The research group has tight collaboration with neuroradiology, ophthalmology, cardiology and clinical nutrition. Our specific aims are: To elucidate the role of neurodegeneration in multiple sclerosis using modern brain imaging and OCT methods in correlation with clinical variables and biomarkers. We also evaluate the correlation of heart rate variability and autonomic dysfunction with neurodegenerative biomarkers To evaluate the role of nutrition and cut microbiome in clinical course of multiple sclerosis
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# The nteract Core SDK ### If you're reading this on GitHub... ...this directory is a Lerna-managed directory that contains the packages that compromise the nteract core SDK. ### If you're reading this on the nteract docs... ...you're probably here to learn more about how to use the nteract core SDK to build your own interactive computing applications. Browse through the links on the right to read the documentation for each package. **Packages moved out of the monorepo** Recently, we made an effort to improve the developer experience and release process for our packages by moving certain packages out of the monorepo and into their own repositories. - [ansi-to-react](https://github.com/nteract/ansi-to-react) - [enchannel-zmq-backend](https://github.com/nteract/enchannel-zmq-backend) - [fs-observable](https://github.com/nteract/fs-observable) - [@nteract/directory-listing](https://github.com/nteract/directory-listing) - [@nteract/dropdown-menu](https://github.com/nteract/dropdown-menu) - [@nteract/logos](https://github.com/nteract/logos) - [@nteract/markdown](https://github.com/nteract/markdown) - [@nteract/mathjax](https://github.com/nteract/mathjax) - [@nteract/octicons](https://github.com/nteract/octicons) - [@nteract/outputs](https://github.com/nteract/outputs) - [@nteract/styled-blueprintjsx](https://github.com/nteract/styled-blueprintjsx)
Q: How to use Jest to test file download? I have some code as below: /* global document */ /* global window */ /* global Blob */ import FileSaver from 'file-saver'; export const createDownloadFromBlob = (blob, filename, extension) => { FileSaver.saveAs(blob, `${filename}.${extension}`); }; export const createDownload = (content, filename, extension) => { createDownloadFromBlob(new Blob([content], { type: 'application/octet-stream' }), filename, extension); }; I want to use Jest to unit-test these two methods, but I don't know where to start. Any help would be appreciated. A: I would mock out FileSaver with a spy: import FileSaver from 'file-saver'; jest.mock('file-saver', ()=>({saveAs: jest.fn()})) As you cant compare Blobs I would mock this as well: global.Blob = function (content, options){return ({content, options})} now you can run your test and use expect like this createDownload('content', 'filename', 'extension') expect(FileSaver.saveAs).toHaveBeenCalledWith( {content:'content', options: { type: 'application/octet-stream' }}, 'filename.extension' )
Move Slow Move Slow Wake up, wake up, wake up Do you feel the movement in your gut Just take two more pills Or this’ll be the last time You’ve gotta make a hit, you’ve gotta make it stick And now it’s running through my blood There’s a five-letter word that’s been Eating away at me They want to steal all my pride They want to steal all my dignity I’m not gonna sit back (I’m not gonna sit back) And let this world get to me Wake me up when it’s said and done Cause I don’t wanna be, no I don’t wanna be Any part of this Have you thought about what we have been through They say move faster Hurry up and give us the good one Don’t put up a fight and don’t make this Any harder than it has to be They want to steal all my pride They want to steal all my dignity I’m not gonna sit back, no! (no, no ..) I just won’t let this go
Q: Does firestore support collection level locks in transaction? I have worked in a mongodb, which is no sql database and it support document level locks only. As firestore is also no sql database, does it support document level locks or it allows collection level locks? A: The only operation you have for locking is document locking with transactions. There is no collection locking in Firestore.
Q: Printing the name of each file with certain extension how can I print out the name of each file in a certain directory with a specific extension? Here's what I have so far: #!/bin/sh DIR="~/Desktop" SUFFIX="in" for file in $DIR/*.$SUFFIX do if [ -f $file ]; then echo $file fi done Unfortunately it doesn't work. What's wrong with it? A: In your DIR="~/Desktop" the "~" not expanded, because it is in "". remove the "". DIR=~/Desktop
Growing up takes a lot of work. It’s important that children get the right vitamins, minerals, and nutrition necessary to keep their developing bodies strong and healthy. Of course, the foods that are best at keeping children in shape aren’t generally the best tasting. At the same time, the holiday season is fast approaching, and unless parents make a conscious effort to monitor their children’s diets, there’s a good chance that those kids will make it from October to January subsisting on nothing but sweets. As such, if parents want to put nourishing food into their kids’ stomachs without having to use a hydraulic press, they often have to resort to tactics that are a bit more... underhanded. So, don’t feel too bad when you use this informative—if somewhat sneaky—infographic on how to sneak veggies into your kids’ meals. Hey, it’s for their own good, right? How do you sneak veggies into meals for your kids? Let us know in the comments below or on Facebook.
National Genomics Center for Wildlife and Fish Conservation The National Genomics Center for Wildlife and Fish Conservation is a facility for advanced research providing expertise in DNA sequencing and environmental and forensic DNA sampling. It is located in Missoula, Montana, and is part of the U.S. Forest Service's Rocky Mountain Research Station. The Center is designed for cross-agency partnerships to provide genetic and genomic data for species monitoring. The center has agreements with the University of Montana for sharing equipment and the U.S. Fish and Wildlife Service to share expertise. The goal of these federal collaborations is reciprocal cooperation that will assist each agency in meeting its responsibilities related to monitoring and maintaining viable wildlife and fish populations and their habitats. Implementation is intended to maintain and enhance agency effectiveness while avoiding duplication of efforts to provide critical conservation genetics and genomics information to the participating agencies. References Category:Forestry agencies in the United States Forest Service Category:Education buildings and facilities in Missoula, Montana
Share this: When Robert Griffin III went down with torn ligaments in his knee during the Redskins’ wild-card weekend loss, speculation began to arise about the conditions at FedEx Field. About a month after the incident forced RG3 into yet another knee surgery — he also had his ACL repaired in college — Ravens safety Ed Reed decided to chime in on the matter. “For all that money down in D.C., you’d think their field would be better,” Reed said during Super Bowl media day festivities in New Orleans on Tuesday. “That field sucks. It does; it was all mud.” The Ravens visited the Redskins just weeks before the infamous playoff game in which RG3 initially injured his knee, so Reed was well aware of the gruesome conditions down in Washington, D.C. Reed and his Ravens teammates fortunately didn’t succumb to any field-related injuries during their dreadful trip to FedEx Field, and they’ll be as close to full health as they’ve been all season when they take the field at the Superdome on Sunday.
The structure-function dilemma of the hammerhead ribozyme. A powerful approach to understanding protein enzyme catalysis is to examine the structural context of essential amino acid side chains whose deletion or modification negatively impacts catalysis. In principle, this approach can be even more powerful for RNA enzymes, given the wide variety and subtlety of functionally modified nucleotides now available. Numerous recent success stories confirm the utility of this approach to understanding ribozyme function. An anomaly, however, is the hammerhead ribozyme, for which the structural and functional data do not agree well, preventing a unifying view of its catalytic mechanism from emerging. To delineate the hammerhead structure-function comparison, we have evaluated and distilled the large body of biochemical data into a consensus set of functional groups unambiguously required for hammerhead catalysis. By examining the context of these functional groups within available structures, we have established a concise set of disagreements between the structural and functional data. The number and relative distribution of these inconsistencies throughout the hammerhead reaffirms that an extensive conformational rearrangement from the fold observed in the crystal structure must be necessary for cleavage to occur. The nature and energetic driving force of this conformational isomerization are discussed.
templates ‘cheeky magpie – the cheap and lazy crafter’ Actually this cute blog has some really lovely and ingenious ideas, tutorials and templates. Check out the hinged cat tutorial with template :: buttons to brads to make this cute flower :: cute and quick lace flowers.
<?php namespace Oro\Bundle\PromotionBundle\Tests\Unit\DependencyInjection; use Oro\Bundle\PromotionBundle\DependencyInjection\Configuration; use Symfony\Component\Config\Definition\Processor; class ConfigurationTest extends \PHPUnit\Framework\TestCase { /** * @var Configuration */ protected $configuration; protected function setUp(): void { $configuration = new Configuration(); $treeBuilder = $configuration->getConfigTreeBuilder(); $this->assertInstanceOf('Symfony\Component\Config\Definition\Builder\TreeBuilder', $treeBuilder); } public function testProcessConfiguration() { $configuration = new Configuration(); $processor = new Processor(); $expected = [ 'settings' => [ 'resolved' => true, Configuration::FEATURE_ENABLED => [ 'value' => true, 'scope' => 'app' ], Configuration::DISCOUNT_STRATEGY => [ 'value' => 'apply_all', 'scope' => 'app' ], Configuration::CASE_INSENSITIVE_COUPON_SEARCH => [ 'value' => false, 'scope' => 'app' ], ] ]; $this->assertEquals($expected, $processor->processConfiguration($configuration, [])); } }
# Definition: tomcat::war # # Manage deployment of WAR files. # # Parameters: # - $catalina_base is the base directory for the Tomcat installation # - $app_base is the path relative to $catalina_base to deploy the WAR to. # Defaults to 'webapps'. # - The $deployment_path can optionally be specified. Only one of $app_base and # $deployment_path can be specified. # - $war_ensure specifies whether you are trying to add or remove the WAR. # Valid values are 'present', 'absent', 'true', and 'false'. Defaults to # 'present'. # _ Optionally specify a $war_name. Defaults to $name. # - $war_purge is a boolean specifying whether or not to purge the exploded WAR # directory. Defaults to true. Only applicable when $war_ensure is 'absent' # or 'false'. Note: if tomcat is running and autodeploy is on, setting # $war_purge to false won't stop tomcat from auto-undeploying exploded WARs. # - $war_source is the source to deploy the WAR from. Currently supports # http(s)://, puppet://, and ftp:// paths. $war_source must be specified # unless $war_ensure is set to 'false' or 'absent'. define tomcat::war( $catalina_base = $::tomcat::catalina_home, $app_base = undef, $deployment_path = undef, $war_ensure = 'present', $war_name = undef, $war_purge = true, $war_source = undef, ) { validate_re($war_ensure, '^(present|absent|true|false)$') validate_bool($war_purge) if $app_base and $deployment_path { fail('Only one of $app_base and $deployment_path can be specified.') } if $war_name { $_war_name = $war_name } else { $_war_name = $name } validate_re($_war_name, '\.war$') if $deployment_path { $_deployment_path = $deployment_path } else { if $app_base { $_app_base = $app_base } else { $_app_base = 'webapps' } $_deployment_path = "${catalina_base}/${_app_base}" } if $war_ensure =~ /^(absent|false)$/ { file { "${_deployment_path}/${_war_name}": ensure => absent, force => false, } if $war_purge { $war_dir_name = regsubst($_war_name, '\.war$', '') if $war_dir_name != '' { file { "${_deployment_path}/${war_dir_name}": ensure => absent, force => true } } } } else { if ! $war_source { fail('$war_source must be specified if you aren\'t removing the WAR') } staging::file { $name: source => $war_source, target => "${_deployment_path}/${_war_name}", } } }
Emeritus Specialist Status Emeritus Specialist status recognizes the past and continuing contribution of a certified lawyer in the advancement of the speciality area through related career activities that do not constitute the actual practice of law.
atmos x Reebok Insta Pump Fury 20th Anniversary Preview Didn’t we already see an atmos x Reebok Insta Pump Fury pair this year? Yes, but that collaboration was almost too subtle to even count, as the model there was only a slight reworking of the original “Citron” colorway. This time around they take some more liberties with this milky white pair that’s got some red and blue accents going on. No release date just yet, but here’s to hoping that they show up soon and are distributed beyond the Japanese shop. Find the full photo for them below and then tell us in the comments what you think of this new Reebok Insta Pump Fury.
Subscription Boxes, If the packaging of your product is apparent, simple, and bold, then it will be more expressive and more convincing to the clients. In this fast world, no one pays attention to all detail of product so, add little detail or use fewer elements to packaging. It can help you to promote your product in many ways. If the packaging design of your product is complicated, then you will surely lose your customers because simplicity is the key. To bring fun, creativity, and innovation in your packaging design, you should know how to play with colors. Rightly choose colors can help the customer to make a quick decision whether to buy a product or not. Choose colors according to your product not too vibrant or not too dull. Roll End Tuck Top Boxes is a design made for packaging any type of materials. This design belongs to the family of top closure style boxes. Roll End Tuck Top Boxes can be a safest container for storing... Subscription boxes is a design of box belonging to the class of fold and assemble style category. These boxes are non-glued and have double walls with tucked ends. The ends at the sides of this box are rolled...
package model import ( "fmt" "regexp" "github.com/kubernetes-incubator/kube-aws/pkg/api" ) type EtcdCluster struct { api.EtcdCluster Network region api.Region nodeCount int } func NewEtcdCluster(config api.EtcdCluster, region api.Region, network Network, nodeCount int) EtcdCluster { return EtcdCluster{ EtcdCluster: config, region: region, Network: network, nodeCount: nodeCount, } } func (c EtcdCluster) Region() api.Region { return c.region } func (c EtcdCluster) NodeCount() int { return c.nodeCount } func (c EtcdCluster) DNSNames() []string { var dnsName string if c.GetMemberIdentityProvider() == api.MemberIdentityProviderEIP { // Used when `etcd.memberIdentityProvider` is set to "eip" dnsName = fmt.Sprintf("*.%s", c.region.PublicComputeDomainName()) } if c.GetMemberIdentityProvider() == api.MemberIdentityProviderENI { if c.InternalDomainName != "" { // Used when `etcd.memberIdentityProvider` is set to "eni" with non-empty `etcd.internalDomainName` dnsName = fmt.Sprintf("*.%s", c.InternalDomainName) } else { dnsName = fmt.Sprintf("*.%s", c.region.PrivateDomainName()) } } return []string{dnsName} } func (c EtcdCluster) LogicalName() string { d := regexp.MustCompile(`\.`) return fmt.Sprintf("Etcd%s", d.ReplaceAllString(c.EtcdCluster.MajorMinorVersion(), `dot`)) }
DigiByte (DGB) is a public, decentralized blockchain that is up to 40x faster than Bitcoin. DigiBytes are digital cryptocurrency assets that can be sent over the DigiByte Blockchain. These transactions are recorded on an immutable ledger that is decentralised across thousands of devices around the world. Digibyte is an interesting example of how not all cryptocurrencies ‘take-off’ in the way … Hashflare was the best response to the growing demand for cloud mining services. Up until that point, their mother company exclusively offered only hosted mining contracts. Propelled by the professional hardware made by HashCoins, HashFlare has the right tool for the job, regardless of your expertise level in the world of cryptocurrency mining. Apart from the mining hardware, their parent …
“I HAVE A THING FOR DOCTORS. ESPECIALLY YOUR KIND.” Doesn’t take long for the reader to realize just how seriously messed-up the world created by TogaQ and Kichiku Neko (a.k.a. “Guilt/Pleasure”) is in their “mature content” yaoi manga In These Words (Digital Manga). Following a brief text piece describing a handsome young’s kidnapping and imprisonment at the hands of a sadistic stalker, we’re shown the first of several graphic scenes featuring a bound male being taunted and sexually mistreated by a mysterious figure. When our hero Asano Katsuya wakes from what we learn is but one of many recent nightmares, we don’t know if the sordid scene we’ve just witnessed is mere imagining, a premonition or a posttraumatic flashback. Our bespectacled protagonist is a psychiatrist who recently helped the police capture a grisly sado-sexual serial killer with twelve known victims to his name. Now said killer, Shinohara Keiji, is only willing to talk to the man who profiled him, so Asano is sent to an isolated undercover holding facility that resembles the Bates Mansion to grill Shinohara. There, interviewer and subject engage in a back-and-forth with the killer growing more grotesquely flirtatious toward the shrink. Though all twelve of his victims were sadistically abused by their captor, none were sexually assaulted. Given the opportunity, Shinohara brazenly states, he would have his way with Asano, though. As this disturbing relationship builds, In These Words regularly flashes to its captivity scenes which steadily grow more explicit. The focus remains primarily on our two-man cast, though two other male figures -- youngish cop Shibata and burly guard Iwamoto -- fulfill basic horror tale secondary roles. (If you guess one of ‘em won’t make it to the end of the first volume, then you know your serial killer horror.) The book’s heavily gray-scaled art (the credits don’t clarify which of our two collaborators actually did the illustrating) gives the whole tale a fifties noir flavor, while the attention to character nuance during the interrogation scenes is particularly strong. There are no cartoonish fillips in the main story, though the book amusingly appends a series of cutesy “chibi” gag strips to the book to keep things from ending on too solidly grim a note. Still, the book definitely is not for younger readers or anyone who might be upset by panels depicting clear digital penetration. The first volume -- which features our hero holding onto a bleeding skull in an “Alas, poor Yorick” pose on its cover -- ends with the promise/threat that the dreadful scenes we’ve already glimpsed will be doubled down in later books. “Guilt/Pleasure” for those who consider Titus Andronicus the entertainment equal of Hamlet. If this blog does not discuss a specific political issue or event, it is not because this writer finds said event politically inconvenient to acknowledge - it's simply because he's scatterbrained and irresponsible.
Bucs safety Andrew Adams said it was "very nerve-wracking" being without a team after the Giants cut him in September. "You know you're a good football player. Why are you watching games on Sunday and not playing? It's a little demoralizing..."
Q: How to fetch YUV stream or bytes array using DirectX? Hi i am creating a sample application using DirectX. I am following a sample application here:http://www.codeproject.com/KB/directx/directxcapture.aspx Can anybody suggest where do we get frames??? i cant understand the sample its working but how??? when i click on Start a file is created with zero bytes when i press Stop some bytes are written to this file. but where do we get frames and bytes array? I need to fetch them for conversion. I am trying to debug but cant get. Can anybody provide some idea or help thanks in advance. A: Finally i got it to work now i am able to obtain yuv data and store the contents in an avi file. I followed this: http://www.codeproject.com/KB/directx/directxcapture.aspx
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Aim of this subproject is to determine the feasibility of comparision of breast images obtained with DOT and PET.
Beckel: Hillary Could Crush Trump ‘From Jail’ Wednesday night on CNN, political commentator Bob Beckel said that Democratic presidential front-runner Hillary Clinton could beat Republican presidential front-runner Donald Trump even if she ends up in prison as a result of the FBI investigation into her handling of classified material on an unsecured email server in her home, during her tenure as secretary of state. Beckel said “In the end, the best-selling Halloween mask this October will be Donald Trump’s face. You go onto a college campus and mention Donald Trump, and people flee for the wood work. Remind me I said this. She will crush him. I mean she could crush him from jail.”
Q: Tzar Balay Chaim- Killing Pests? Are you allowed to kill flies and other pests (mice, mosquitoes, etc.) or would that go under the prohibition of Tzar Balay Chaim? A: Reb Moshe in Iggras Moshe (חושן משפט חלק ב' סימן מ''ז) says if it is disgusting and or the creature ruins food,or mosquitoes who bother the person the answer is YES. Reb Moshe in an Illustration of his Tzidkus (righteousness) adds of course you should try not do it by hand instead with fly traps and the like because killing by hand desensitizes you and ruins your character. He brings the Ohr Hachaim Hakodsh (דברים י"ג י"ח) who says that even the person who kills for the Beis Din and a Shochet needs a special protection against this provided by the Torah because he is directly involved in doing a Mitzvah but here where he is just ridding himself of a bother he should try his utmost not to do it by hand.
Q: How to remove extra in WordPress? I'm new to wordpress and currently developing a theme on it. I have noticed that Wordpress adds <p> tags all over the page. Do you know any plugin or a workaround to avoid this? A: Add this to your functions.php, this should give the result you're looking for: remove_filter('the_content', 'wpautop');
Q: What is the difference between the blackness of a Black Hole and the blackness of a Black Body? Light cannot escape the gravitational pull of the black hole and hence the 'black hole' is black. Any object that is black in color, absorbs all wavelengths of light and reflects none. So it appears black. Could someone explain the key difference between these two phenomena ? A: A black body is a system that does not reflect photons. A black body can only emit photons, which is often fabricated as a hot cavity with a small hole. A razor blade can also approximate a black body if the sharp edge is smaller than the wavelength of photons of interest and is at a temperature so short wavelength photons are not significantly present. A black body then has a small reflectivity relative to the emissivity $r(\lambda)~<<~\epsilon(\lambda)$ for wavelengths of interest. An ideal black body has zero reflectivity for all wavelengths. A black hole absorbs anything, including photons that reach it. It has zero reflectivity. Even if a photon entering a black hole reaches a mirror that is right at the event horizon, since the mirror has $z~\rightarrow~\infty$ the photon is not reflected back. The black hole also interacts with the quantum vacuum, in that virtual quanta across the horizon becomes an entangled pair of a negative energy quanta entering the black hole and a positive energy quanta that escapes to "infinity." This is a bit of heuristic, but it helps us see that a black hole losses a bit of mass and that mass escapes. The low energy form of this is of course photons, which have zero mass gap. As a result a black hole is about the most ideal black body in the universe.
Sixteen years on: has quality of care for rural and non-compensable traumatic brain injury clients improved? This review focuses on two factors that influence client access to care following head injury. These factors, namely the degree of rurality of a client's home town and the funding model to which they are allocated, are discussed in light of the results of the 'Head Injury Impact Project'. National and international publications, anecdotal reports and clinical experience illustrating current practices in care provision both nationally and internationally are then described. Finally, future research is proposed investigating perceived variations in access to services according to location, funding and other factors.
Tescalcin expression contributes to invasive and metastatic activity in colorectal cancer. We reported previously that tescalcin (TESC) levels were higher in tissue and serum from colorectal cancer (CRC) patients and suggested that TESC was a potential oncotarget in CRC. The aim of this study was to investigate the function of TESC in CRC invasion and metastatic potential. TESC expression was knocked down in CRC cells using small interfering RNA (siRNA). The expression of TESC siRNA reduced cell migration and invasion by inhibiting matrix metalloprotease (MMP) and the epithelial-mesenchymal transition (EMT) pathway. RT-PCR and Western blot analysis showed that TESC siRNA induced E-cadherin. Consistently, TESC overexpression in HCT116 (HCT/TESC) cells enhanced cell migration and invasion by activating MMP and the EMT pathway and reducing E-cadherin. The formation of liver metastatic nodules in vivo was strongly increased in mice injected with HCT/TESC cells compared with that in mice injected with HCT/mock cells. This study demonstrates that TESC is involved in cell migration, invasion, and EMT during CRC tumor invasion. These results implicate TESC as a metastatic mediator and provide a biological rationale for the adverse prognosis associated with elevated TESC expression in human CRC.
Vertebrate vitellogenesis: molecular model for multihormonal control of gene regulation. The stimulation of yolk protein synthesis by estrogen is a characteristic of female non-mammalian vertebrates; in mammals, however, vitellogenesis has been suppressed as a corollary of the evolution of viviparity. It is our hypothesis that progesterone has a dual role in this phylogenetic trend; a) to inhibit myometrial contraction and thus set the stage for internal development of embryos and associated placentation, b) to inhibit yolk protein synthesis as placentation became an efficient direct supply of nutrients to the fetus. We have presented evidence that in the reptiles, the central vertebrate group from which the ancestors of modern mammals evolved, the control of yolk protein synthesis is complex, involving both pituitary and ovarian steroids (estradiol, testosterone and progesterone). This system provides an excellent model for the multihormonal contents of gene regulation involving both + and - controls.
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For the past couple of days I saw Taco Bell trending, majority of the people tweeting were thin/skinny. All of them discussing their Taco Bell loyalty and saying how much they love it and eat it A LOT. Meanwhile a fat person is accused every day of being fat because people assume that a fat person eats to much fast food. The fucking irony of it al!! But this is common. Every where I frequent thin people post their favorite thing from some fast food place and no one bats an eyelash, their other thin buds join in on the fiesta of fast food orgasms. I mean mainly thin people are used in fast food commercials for Pete’s sake because the powers that be want to continue promoting this skewed inaccurate message that “Hey they’re thin so they probably don’t eat that often and most of the time eat healthy” whereas using a person of size in a fast food commercial would have people thinking “Oh God I better slack on the Taco Bell before I look like that”. Thin privilege is being able to be or publicly say you are a constant consumer of fast food but still have the general public and doctors believe you are healthy and eat a balanced diet.
const User = require('../models/user.js'); /** * 根据用户名列表查找用户列表 * @param {Array} names 姓名数组 * @returns {Array} users 用户数组 */ exports.getUsersByNames = async(names) => { if (!names) { return []; } return await User.findAll({ where: { name: names, }, }); }; exports.getUserById = async(id) => { if (!id) { return []; } return await User.findById(id); }; exports.getUserByEmail = async(email) => { if (!email) { return {}; } return await User.findOne({ where: { email: email } }); }; exports.getUserByName = async(name) => { if (!name) { return {}; } return await User.findOne({ where: { name: name } }); }; exports.createUser = async(user) => { if (!user) { return {}; } return await User.create(user); }; exports.updateUser = async(id, info) => { if (!id || !info) { return {}; } return await User.update( info, { where: {id: id} }); }; exports.addIntegration = async(id, integration)=> { if (!id || !integration) { return {}; } let user = await User.findById(id); return await User.update( { integration: integration + user.integration, }, { where: {id: id} }); }
Validating affinities for ion-lipid association from simulation against experiment. Understanding biological membranes at physiological conditions requires comprehension of the interaction of lipid bilayers with sodium and potassium ions. These cations are adsorbed at palmitoyl-oleoyl-phosphatidylcholine (POPC) bilayers as indicated from previous studies. Here we compare the affinity of Na(+) and K(+) for POPC in molecular dynamics (MD) simulations with recent data from electrophoresis experiments and isothermal calorimetry (ITC) at neutral pH. NaCl and KCl were described using GROMOS or parameters matching solution activities on the basis of Kirkwood-Buff theory (KBFF), and K(+) was also described using parameters by Dang et al., all in conjunction with the Berger parameters for the lipids and the SPC water model. Apparent binding constants of GROMOS-Na(+) and KBFF-K(+) are the same within error and in good agreement with values from ITC. Although these force fields yield the same number of bound ions per number of lipids for Na(+) and K(+), they give a larger number of Na(+) ions per surface area compared to K(+), in agreement with the electrophoresis experiments, because Na(+) causes a stronger reduction in the area per lipid than K(+). The intrinsic binding constants, on the other hand, are reproduced by Dang-K(+) but overestimated by GROMOS-Na(+) and KBFF-K(+). That no ion force field reproduces the intrinsic and the apparent binding constant simultaneously arises from the fact that in MD simulations, implicitly meant to mimic neutral pH, pure PC is usually modeled with zero surface charge. In contrast, POPC at neutral conditions in experiment carries a low but significant negative surface charge and is uncharged only at acidic pH as indicated from electrophoretic mobilities. Implications for future simulation and experimental studies are discussed.
Pressure-regulated biosynthesis of cytochrome bd in piezo- and psychrophilic deep-sea bacterium Shewanella violacea DSS12. The genes of cytochrome bd-encoding cydAB were identified from a deep-sea bacterium Shewanella violacea DSS12. These showed significant homologies with known cydAB gene sequences from various organisms. Additionally, highly conserved regions that are important for the enzymatic function were also conserved in cydA of S. violacea. Based on the results, transcriptional analysis of cydAB operon and cydDC operon (required for assembly of cytochrome bd) of S. violacea in microaerobic condition was performed under the growth condition of various pressures. The gene of cydA was expressed even under the condition of atmospheric pressure and its expression was enhanced with pressurization. On the other hand, the expression of cydC was strongly depressed under the condition of atmospheric pressure compared with the case under high pressure. It appeared spectrophotometrically that loss of cytochrome bd in S. violacea under atmospheric pressure shown in previous study is caused mainly by the loss of cydDC. Further, under the growth condition of atmospheric pressure, either less amount or no d-type cytochrome was expressed compared with the case of high-pressure condition even if the organism was grown under alkaline condition or in the presence of uncoupler, which are the inducible condition of d-type cytochrome in Escherichia coli. These results suggested that the significant amount of d-type cytochrome expression is specific event under the growth condition of high pressure.
Q: BPL en Delphi con FLAG "Link With Runtime Link Package" en False Tengo un proyecto que usa una BPL desarrollada por mi sobre Delphi Rio o Delphi Tokyo. Con el FLAG "Link With Runtime Link Package" en TRUE el proyecto compila, pero con el Flag en FALSE no compila porque no encuentra las unidades de la BPL. Al compilar con el Flag en False, pretendo que el ejecutable incluya las BPL's, si no debo distribuir las BPL's propias y de Delphi con el ejecutable. Gracias A: Para que tu proyecto compile sin utilizar la BPL en tiempo de corrida, debes incluir la ruta dónde tienes las unidades dentro del library path, para que el compilador sea capaz de encontrarlas y enlazarlas dentro de tu ejecutable. Al compilador puedes darle: Los fuentes (.pas) de las unidades o DCU's de las unidades, siempre que sean compatibles con la versión del compilador. Para ello, puedes hacerlo a nivel global (es lo más común si el BPL contiene componentes propios). En el menú, Tools > Options > Language > Delphi Options > Library > Library path incluye la ruta de la carpeta donde tengas los archivos mencionados. También puedes hacerlo dentro de las opciones del proyecto, si no quieres que estas unidades estén disponibles para otros proyectos.
Deep Learning Could Automate TSA Screeners - icinnamon https://medium.com/synapse-blog/ai-outperforms-certified-xray-operators-972932086f2e ====== sgautam Hi all- I'm the CTO and Co-founder of Synapse Technology. Happy to answer questions about our tech & product! p.s. We're hiring CV engineers for our Perception Team. Shoot me a note at sims[at]syntechcorporation.com if you're interested in solving hard problems with state-of-the-art methods in object detection, domain adaptation, incremental learning, and the like! ------ rkwasny Should we just keep the government shut and replace it with AI? ~~~ icinnamon You joke, but there are certain aspects that could be made far more efficient and accurate with AI.
Q: Dependency injection in Spring. not convenient regarding to prototype scope Spring's DI works fine for singleton scope bean. However, regarding to prototype scope it is not convenient if the prototype bean itself will inject other beans. The thing is for prototype bean, I would like to create them using new keyword of Java with runtime constructor arguments which is hard to be statically described in XML bean configuration. Using new keyword makes the prototype bean out of Spring container, it is impossible to use Spring DI in them of course. I am wondering how people solve problem like this? Of course I can use AspectJ to do myself injection as a compensation. But having two injection mechanisms is not an elegant solution to me. A: Mark you prototype bean with @Configurable
Q: Page.Validate vs Page.IsValid What is the difference between Page.Validate and Page.IsValid? I read some articles about that Page.Validate method is fired automatically by controls that have the CausesValidation property set to true(Which is default value for Button control). Page.IsValid property tells you whether the validation succeeded or not. But Which one is better? what was the relation between us? A: Page.Validate is a method, Page.IsValid is a property. The former forces validation of one or all validation-groups (if no group is specified), the latter returns the result of this validation. You don't need to call Page.Validate manually if the control that caused the postback has CausesValidation set to true(default). Q: Why would you want to force validation on serverside at all or why would you want to set CausesValidation to false? A: Sometimes you don't want to force validation on clientside always but only under certain conditions that are checked on serverside. Or you want to combine multiple validation-groups.
[Natural history of gastric cancer linked to Helicobacter pylori]. Gastric carcinogenesis is related to inflammatory reaction induced by Helicobacter pylori infection. Infection is involved in pathogenesis of both histological types of gastric cancer, intestinal or diffuse. In the first type, cancer is the last step of successive alterations of the gastric mucosa (atrophy, intestinal metaplasia, dysplasia). In the second type, cancer occurs faster due to chromosomic alterations related to oxidative stress. Inflammation and consequently cancer risk are modulated by bacterial virulence and by the immunologica responsiveness of the host. Helicobacter pylori eradication should be proposed to high risk patients: first degree relatives of patients having gastric cancer, patients with preneoplastic lesions. Cancer prevention is more effective when eradication is performed before occurrence of preneoplastic lesions. When preneoplastic lesions are present, eradication decreases but not suppresses the risk of cancer. Therefore periodic follow up with gastroscopy and biopsies should be planned in these patients.
#!/bin/bash aclocal autoheader automake --add-missing --copy --foreign autoconf
#include "RecoTracker/Record/interface/MultiRecHitRecord.h" #include "FWCore/Framework/interface/eventsetuprecord_registration_macro.h" EVENTSETUP_RECORD_REG(MultiRecHitRecord);
New York Times columnist Paul Krugman writes that regardless of the election outcome, the Republican Party will remain wedded to the issues that propelled the rise of GOP nominee Donald Trump. After all, what we learned during the Republican primary was that the party’s base doesn’t care at all about what the party establishment says: Jeb Bush (remember him?), the initial insider choice, got nowhere despite a giant war chest, and Mr. Rubio, who succeeded him as the establishment favorite, did hardly better. Nor does the base care at all about supposed conservative principles like small government. What Republican voters wanted, instead, were candidates who channeled their anger and fear, who demonized nonwhites and played into dark conspiracy theories. (Even establishment candidates did that — never forget that Mr. Rubio accused President Obama of deliberately hurting America.) Just in case you had any doubts about that political reality, a Bloomberg poll recently asked Republicans whose view better matched their own view of what the party should stand for: Paul Ryan or Donald Trump. The answer was Mr. Trump, by a wide margin. This lesson hasn’t been lost on Republican politicians. Even if Mr. Trump loses bigly, they’ll know that their personal fortunes will depend on maintaining an essentially Trumpist line. Otherwise they will face serious primary challenges and/or be at risk of losing future elections when base voters stay home.
I can't imagine living somewhere that donair pizza wasn't a thing. Yet in parts of Canada you can't get good donair pizza! As my first Year of Donair post, let's take a moment to celebrate some donair pizza.
API === Entry Points ------------ .. currentmodule:: datashader **Canvas** .. autosummary:: Canvas Canvas.line Canvas.points Canvas.raster Canvas.trimesh Canvas.validate .. currentmodule:: datashader **Pipeline** .. autosummary:: Pipeline Edge Bundling ------------- .. currentmodule:: datashader.bundling .. autosummary:: directly_connect_edges hammer_bundle Glyphs ------ .. currentmodule:: datashader.glyphs **Point** .. autosummary:: Point Point.inputs Point.validate .. currentmodule:: datashader.glyphs **Line** .. autosummary:: Line Line.inputs Line.validate Reductions ---------- .. currentmodule:: datashader.reductions .. autosummary:: any count count_cat by first last m2 max mean min mode std sum summary var Transfer Functions ------------------ .. currentmodule:: datashader.transfer_functions **Image** .. autosummary:: Image Image.to_bytesio Image.to_pil .. currentmodule:: datashader.transfer_functions **Images** .. autosummary:: Images Images.cols .. currentmodule:: datashader.transfer_functions **Other** .. autosummary:: dynspread set_background shade spread stack Definitions ----------- .. currentmodule:: datashader .. autoclass:: Canvas .. autoclass:: Pipeline .. currentmodule:: datashader.bundling .. autoclass:: directly_connect_edges .. autoclass:: hammer_bundle .. currentmodule:: datashader.glyphs .. autoclass:: Point .. autoclass:: Line .. currentmodule:: datashader.reductions .. autoclass:: any .. autoclass:: count .. autoclass:: count_cat .. autoclass:: first .. autoclass:: last .. autoclass:: m2 .. autoclass:: max .. autoclass:: mean .. autoclass:: min .. autoclass:: mode .. autoclass:: std .. autoclass:: sum .. autoclass:: summary .. autoclass:: var .. automodule:: datashader.transfer_functions :members:
Solid-State Conversion Synthesis of Advanced Electrocatalysts for Water Splitting. Electrolytic water technology is promising for sustainable energy utilization, but the lack of efficient electrocatalysts retards its application. The intrinsic activity of electrocatalysts is determined by its electronic structure, whereas the apparent activity can be further optimized by reasonable design on micro-/nanostructures of electrocatalysts. The core goal of electrocatalytic research is to reveal the relationship between the structure and performance of electrocatalysts, which is also the basis of reasonable design and construction of efficient electrocatalysts. Traditional synthetic methods, namely bottom-up and top-down routes, usually induce the change of different structural parameters at the same time. The solid-state conversion strategy, which is converts solid precursors into target materials through chemical reactions, has been widely adopted to produce materials with precisely controllable structures. In this Minireview, we focus on recent advances in the solid-state conversion synthesis of water-splitting electrocatalysts. First, the basis of solid-state conversion chemistry is introduced. Then, the specific methods of precise control of electronic structure by solid-state conversion and the relationship between electronic structure and performance are summarized. Based on the understanding of the electronic structure-performance relationship, synergistic regulation of electronic structure and micro-/nanostructures by solid-state conversion to achieve the copromotion of intrinsic activity and apparent activity are described. Finally, the remaining challenges in this field are discussed, and future research directions are proposed as well.
“The Iranian nuclear issue has become the main pillar of the regime’s legitimacy,” said Mustafa el-Labbad, an Iran expert in Cairo. “So Ahmadinejad is putting it in the center of the scene in order to conceal the internal differences and huge domestic challenges they face.” It is not at all clear how much uranium has been enriched or whether Iran has the capacity to transform that into either weapons-grade fuel or even into the fuel rods necessary for running the medical research reactor it says it aims to supply. The Obama administration dismissed the idea that Iran had the capacity to enrich uranium to weapons grade. The White House press secretary, Robert Gibbs, said, “Iran has made a series of statements” that were “based on politics, not on physics,” The Associated Press reported. Mr. Ahmadinejad’s speech, delivered from a platform decorated with flowers, was heard by a largely sympathetic crowd that had been bused in from around the country to celebrate the most important political celebration of the year. The day is similar to the Fourth of July in the United States or Bastille Day in France, and like those holidays it is steeped in myth and symbolism. Both the opposition and the government hoped to control the message of the day. The opposition leaders, Mir Hussein Moussavi and Mehdi Karroubi, had called on their supporters to fill the streets, though they had not offered a clear plan. The government provided little room for the opposition to gain traction. It sent thousands of security officers into Azadi Square the night before to intimidate the opposition and, if necessary, block it from participating. Those who attended the rally disappeared in a sea of government supporters.
Article content Foreign Affairs Minister Stéphane Dion says Canada will be more constructive in its diplomatic dealings with Iran and Russia, but that caution and assertiveness will remain central to its approach. In an interview with the Citizen on Wednesday, Dion said the new Liberal government also won’t shy away from criticizing either Israel or the Palestinians when it comes to actions that threaten Middle East peace. And he wouldn’t rule out Canada running for a seat at the United Nations Security Council. We apologize, but this video has failed to load. tap here to see other videos from our team. Try refreshing your browser, or Canada ready to re-engage with Russia, Iran, despite differences, Dion says Back to video “I cannot tell you when we will ask to come back to the council,” he said. “But it is certainly something that we need to consider because the world needs Canada to be at the core of the decision-making process.” One of Prime Minister Justin Trudeau’s first promises after last month’s election was that Canada would have a more “compassionate and constructive voice in the world” under the Liberals after a decade of Conservative rule. As Trudeau’s new foreign affairs minister, it will be up to Dion to implement that vision.
recursive-include docs * recursive-include util * recursive-include skins * recursive-include examples * include LICENSE.txt include README include weewx.conf exclude **/junk*
Tuesday’s Tumblr of the day: Animals talking in all caps If there’s one thing that guarantees a reblog on Tumblr it’s a post of a kitten or cute animals. You can’t not stop and stare at this cute panda, uh? On ANIMALS TALKING IN ALL CAPS, Justin Valmassoi, the creator, takes photos of animals and adds hilarious captions imagining the little animal in real life human situations.
A portion of the disclosure of this patent document contains material that is subject to copyright protection. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure, as it appears in the Patent and Trademark Office patent file or records, but otherwise reserves all copyright rights whatsoever. This invention relates generally to electronic appliance controls and, more particularly, to reconfigurable control systems for electronically controlled appliances. At least some known appliances include an electronic appliance control that is programmed by a manufacturer i.e., originally programmed. An appliance owner desiring to upgrade an electronic appliance control has had little choice but to replace the entire appliance. However, replacing the appliance in order to obtain the benefits of an upgraded electronic control and/or upgraded programming for the control is typically not cost effective. In one aspect, a method for changing a control program that controls at least some operations of an appliance is provided. The appliance includes at least one electronic control that executes the control program. The method includes connecting the electronic control to a communication device configured to communicate with at least one user device via a network. The method also includes changing the control program via the user device and the network. In another aspect, a method for operating an appliance controlled by a dedicated appliance controller interfacing with an appliance communication controller is provided. The appliance communication controller is configured to interpret and transmit control data for operating the appliance to the dedicated appliance controller. The appliance communication controller is connected to a modem. The method includes establishing a communication link with the appliance communication controller using the modem and supplying control data to the appliance communication controller using the communication link. In yet another aspect, a communication interface for operating an appliance controlled by a dedicated appliance controller is provided. The interface includes an appliance communication controller interfacing with the dedicated appliance controller and an external host controller interfacing with the appliance communication controller and configured to receive control data from an operator.
A water-soluble PEGylated RGD-functionalized bisbithiophenyl diketopyrrolopyrrole as a photoacoustic sonophore. Photoacoustic imaging presents an innocuous imaging modality with good penetration depth and resolution. To use this modality for detection and imaging of pathological sites, new imaging probes need to be developed to enhance the contrast over endogenous sonophores. These contrast agents should specifically bind to the site of interest, be non-toxic and be cleared renally if applied intravenously. Small organic dyes with absorption in the near infrared spectrum often exhibit good photoacoustic response. However, such dyes are often not water soluble or they are cytotoxic. Here, we present a novel PEGylated sonophore based on diketopyrrolopyrrole (DPP), which overcomes these limitations and can be functionalized with desired biological recognition motifs using thiol-yne click chemistry. Proof of concept is demonstrated by functionalizing the DPP-based probe with an RGD peptide, resulting in specific binding to endothelial (HUVEC) cells and an efficient photoacoustic response.
'use strict'; // startegies to get the list of apps to compare module.exports = { SIMILAR: 'similar', // listed as similar in google play COMPETITION: 'competition', // top apps of the targetted kws CATEGORY: 'category', // top apps of the category ARBITRARY: 'arbitrary', // based on an arbitrary list of app ids KEYWORDS: 'keywords', // based on a list of seed keywords SEARCH: 'search' // based on search suggestion keywords };
True but not false memories produce a sensory signature in human lateralized brain potentials. False memories (e.g., recognition of events that did not occur) are considered behaviorally and subjectively indistinguishable from true memories. We report that brain activity differs when true and false memories are retrieved. Strongly associated lists of words were presented to one or the other cerebral hemisphere at study. This led to lateralized brain activity for these words during a centrally presented recognition test, reflecting their lateralized encoding. This activity was absent for nonstudied but strongly associated words falsely recognized as studied items. These results indicate that studied words leave sensory signatures of study experiences that are absent for false memories. In addition, hemifield effects emerged, including a slower reaction time (RT) for false recognition of nonstudied words whose associated lists were presented to the left hemifield (i.e., right hemisphere). These false recognition responses were accompanied by frontal slow wave activity, which may reflect a differential ability of the two hemispheres with respect to semantic processing.
--- layout: doc-api.html tags: internal, shadow-dom, argument-list --- # ally.get.shadowHost Identifies the `ShadowHost` of an element ## Description ## Usage ```js var element = ally.get.shadowHost({ context: '#element-to-start-from', }); ``` ### Arguments | Name | Type | Default | Description | | ---- | ---- | ------- | ----------- | | context | [`<selector>`](../concepts.md#selector) | *required* | The element to start searching from. The first element of a collection is used. | ### Returns [`HTMLElement`](https://developer.mozilla.org/en/docs/Web/API/HTMLElement). ### Throws [`TypeError`](https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/TypeError) if `context` option is not specified. ## Examples ## Notes ## Related resources * [`ally.get.shadowHostParents`](shadow-host-parents.md) uses this module to identify the `ShadowHost` ancestry ## Contributing * [module source](https://github.com/medialize/ally.js/blob/master/src/get/shadow-host.js) * [document source](https://github.com/medialize/ally.js/blob/master/docs/api/get/shadow-host.md) * [unit test](https://github.com/medialize/ally.js/blob/master/test/unit/get.shadow-host.md.js)
<?php namespace Oro\Bundle\ProductBundle\Provider; use Oro\Bundle\ProductBundle\Entity\Product; interface ProductsProviderInterface { /** * @return Product[] */ public function getProducts(); }
Limited DNA Repair Gene Repertoire in Ascomycete Yeast Revealed by Comparative Genomics. Ascomycota is the largest phylogenetic group of fungi that includes species important to human health and wellbeing. DNA repair is important for fungal survival and genome evolution. Here, we describe a detailed comparative genomic analysis of DNA repair genes in Ascomycota. We determined the DNA repair gene repertoire in Taphrinomycotina, Saccharomycotina, Leotiomycetes, Sordariomycetes, Dothideomycetes, and Eurotiomycetes. The subphyla of yeasts, Saccharomycotina and Taphrinomycotina, have a smaller DNA repair gene repertoire comparing to Pezizomycotina. Some genes were absent from most, if not all, yeast species. To study the conservation of these genes in Pezizomycotina, we used the Gain Loss Mapping Engine algorithm that provides the expectations of gain or loss of genes given the tree topology. Genes that were absent from most of the species of Taphrinomycotina or Saccharomycotina showed lower conservation in Pezizomycotina. This suggests that the absence of some DNA repair in yeasts is not random; genes with a tendency to be lost in other classes are missing. We ranked the conservation of DNA repair genes in Ascomycota. We found that Rad51 and its paralogs were less conserved than other recombinational proteins, suggesting that there is a redundancy between Rad51 and its paralogs, at least in some species. Finally, based on the repertoire of UV repair genes, we found conditions that differentially kill the wine pathogen Brettanomyces bruxellensis and not Saccharomyces cerevisiae. In summary, our analysis provides testable hypotheses to the role of DNA repair proteins in the genome evolution of Ascomycota.
using System; namespace LinqToTwitter { /// <summary> /// Search for tweets with different types of attitudes /// </summary> [Flags] public enum Attitude { /// <summary> /// Happy /// </summary> Positive = 0x01, /// <summary> /// Sad /// </summary> Negative = 0x02, /// <summary> /// Curious /// </summary> Question = 0x04 } }
module ActiveAdmin module Inputs module Filters class StringInput < ::Formtastic::Inputs::StringInput include Base include Base::SearchMethodSelect filter :contains, :equals, :starts_with, :ends_with # If the filter method includes a search condition, build a normal string search field. # Else, build a search field with a companion dropdown to choose a search condition from. def to_html if seems_searchable? input_wrapping do label_html << builder.text_field(method, input_html_options) end else super # SearchMethodSelect#to_html end end end end end end
Now what I want you to know is that most people are facing some sort of money fear BECAUSE it’s being broadcast and programmed into each and every one of you. When we sit in fear of money, we release our hold on value for self. And without value for self you can’t manifest big dreams of correction. And you don’t value yourself and still worry about money. If you value yourself you KNOW you will figure a way out or that you will do whatever it takes to rise and discover the journey to abundance. When you value yourself you know you got it in you, you trust that you are here for a reason and you surrender into the universe revealing to you the wisdom of the ways.
Diarrhea in the immunocompromised patient. Diarrhea is a common problem in patients with immunocompromising conditions. The etiologic spectrum differs from patients with diarrhea who have a normal immune system. This article reviews the most important causes of diarrhea in immunocompromised patients, ranging from infectious causes to noninfectious causes of diarrhea in the setting of HIV infection as a model for other conditions of immunosuppression. It also deals with diarrhea in specific situations, eg, after hematopoietic stem cell or solid organ transplantation, diarrhea induced by immunosuppressive drugs, and diarrhea in congenital immunodeficiency syndromes.
Whitaker: Well, what I see is a President that is starting to figure out his influence that he can have on this investigation. And someone that is trying to send a message to the special prosecutor, Bob Mueller, that listen, you have a lot of power and you are now the keeper of the cloud that hangs over this administration, unfortunately, but I can still affect you. I can reach out and if I want to, I can terminate you. I think that is very dangerous politically, but legally there is certainly a way for that to happen. Lemon: You don’t think that’s dangerous legally, it’s not obstruction? He is saying basically unless it goes my way, I’m going to fire you. Whitaker: No, I don’t think that’s obstruction, because—we keep using that term. And I know we have discussed it before, Don. But I just – I don’t think that under these facts and circumstances that an obstruction of justice charge, either in the context that we have originally talked about with his discussions with Jim Comey or in this new context of talking about the possibility of Bob Mueller losing his job as special counsel, I think neither one of those would raise to the level of obstruction.
To move Page Layers, click and drag a layer and click the “z” button to reset the order of the layers (front to back). To add a note or comment to a Page Layer, select the Page Layer and type text in the Note text field. To delete a Page Layer, select the Page Layer and click the Delete button. If the Page Layer contains graphics, you’ll be given a chance to cancel, keep the graphics by moving them to the Default Layer, or delete the Page Layer and its graphics. • If you delete a locked layer and keep the graphics, the graphics will remain locked. To move graphics to a Page Layer, select the graphics you want to move, select the Page Layer you want to move them to, and click the Move Items to Layer button.
Breaking bad news: current prospective and practical guideline for Muslim countries. Breaking bad news is one of the most distressing tasks which face physicians on daily basis; however, only few doctors receive formal training on this task. Disappointingly, the current status of the "breaking bad news" sector in health care systems in the Muslim countries is largely unknown. The following article attempts to address the current status of breaking bad news in the health care sector in Muslim countries and devises a practical protocol which provides a stepwise framework for breaking bad news in Muslim countries.
Shahul Medicals Logo Design Identity is the talking face; the first impression a consumer makes of any and every brand/company. Our Client Shahul Medicals, wanted to tune up their existing logo identity. So we brought in the zigzag ‘ecg reading’ symbol to convey the ‘medical aspect’ of Shahul Medicals, settled at a blue-green colour palette that’s universally relatable to the medical world and blended it with the rest.
This invention relates generally to container systems, and more particularly to a container system used in the delivery of viscous fluids, such as lubricants. The proper lubrication of mechanical systems requires the delivery of a suitable lubricant (e.g., grease) at regular intervals to various points of lubrication. A typical source of lubricant is a container system comprising a container filled with grease, and a follower in the container above the grease which moves up and down as the level of grease in the container rises and falls. Lubricant is pumped under pressure from the container to locations where the lubrication is needed. Conventional systems have not been provided with suitable means for monitoring the level of grease in a container. By way of example, one such system uses a switch mounted on the lid of the container, a mass which rests on the follower in the container, and a flexible line connecting the mass to the switch. The length of the flexible line is such that when the follower descends to a level indicating that the container is substantially empty, the weight of the mass transfers from the follower to the flexible line and actuates the switch to indicate that the container needs to be refilled. However, until the switch is activated, there is no means for determining the level of fluid in the container, short of removing the lid. Further, when the container is refilled, there is no convenient means for determining when the container is full except by overflow of lubricant from the container, or by other means which are not convenient. In one prior art system, a mass is attached to the container lid by a flexible line to suspend the mass at a location inside the container corresponding to the desired maximum fill level. When the follower rises to the maximum fill level, it lifts the mass which activates a switch to stop the pump. There is a need, therefore, for a system capable of sensing the level of viscous fluid (e.g., grease) in such containers not only when the fluid level is low but also at other levels so that the amount of fluid remaining in the container can be monitored on a continuous basis after the container is filled.
Rather than ramping up some imaginary "red line", perhaps we should sit down with Indonesia and formulate a regional solution to people smuggling. James Giggacher writes. Prime Minister Tony Abbott is speaking like a Leviathan, that political behemoth of Thomas Hobbes' mind who straddles a territory and controls all within. This domain is mine, it bellows. I am sovereign here, and I shall be obeyed and no one shall usurp me. Sovereignty is one of the founding ideas of Western political philosophy and has set the tone for modern states; they cling to the ideal and the supposed infallible right to govern without interference it is meant to give them. But for my mind, Abbott and his Government's notion of sovereignty is a worldview increasingly out of touch with today's world. And so in the latest Australia-Indonesia fallout over people smuggling, his comments about "stopping the boats" are simply too sincere to be ironic. Abbott told journalists on Tuesday: The great thing about stopping the boats is that it has very much improved our relationship with Indonesia. We will do whatever is necessary within the law, consistent with our standards as a decent and humane society, to stop the boats because ... that's the moral thing to do. The only thing that really counts is: have we stopped the boats? And the answer is a resounding yes. That's what it comes down to; stopping the boats at any cost (by hook or by crook) goes hand-in-hand with preserving Australia's sovereignty. It represents a new high watermark in the obsession with our territorial integrity and the overinflated threat to it that asylum seekers arriving by boat pose. Abbott has cordoned off Australian shores from any incursion from those not wanted or who arrive in ways unacceptable to such an extent that now his Government has allegedly paid people smugglers to return to Indonesian shores with the desperate human cargo they ferry. So desperate with the idea of border protection is this current Government that Foreign Minister Julie Bishop issued her own salvo at Indonesia, telling it to fix theirs. Jakarta has expressed shock. And so Australia's obsession has once again got Indonesia off side. Having already antagonised our neighbour in the past, this latest development will serve to put the relationship back where it all too often is - out in the cold. Get The Drum in your inbox Subscribe to get The Drum delivered to your email twice a day, plus top news headlines and alerts on major breaking stories. To hammer home the message, Indonesia's vice-president Jusuf Kalla has weighed in on the issue, comparing Australia's alleged actions to bribery. He also said they were not according with "the ethics of international relationships". He has a point. But while the ethics are just as important, particularly in light of our responsibilities under international human rights conventions, Abbott's position is just as revealing in that it shows how out of touch he is with the realities of global politics. His view is what some experts would label "domestic sovereignty", or a focus on effective control within borders. It's more in line with traditional "Westphalian" models, which privilege no interference. But sovereignty, a fuzzy concept from the outset, can today also be seen as being "interdependent", where global processes and flows, like the movement of people, begin to erode domestic control. This is what Abbott is staring down now. But sometimes you simply need to learn to look at a problem in a different light. And sometimes staying in control comes with the ability to make concessions. After all, even Leviathan, to stay on the throne, had to give citizens rights and protection. This is exactly what Indonesia, a post-colonial sprawl of many thousands of islands nervous about its own territorial integrity, did in the recent Rohingya boat people crisis. After maintaining a hardline stance it agreed to settle some of the migrants - albeit only for one year. Of course the less boats the better. But at the same time we need to recognise that strictly enforcing boundaries, which are a lot fuzzier than Abbott would have us believe, can be extremely counterproductive. These are complex issues. I am not suggesting we open the "floodgates", but a more humane interpretation of the lines on a map would countenance dealing with those boats that do cross in a humane and respectful way. Rather than ramping up some imaginary "red line" and regional tensions, perhaps time and resources could be better spent sitting down with our neighbours and formulating a regional solution to smuggling. Showing flexibility on your own red lines has the virtue of demonstrating you are willing to do so when negotiating. Abbott and Indonesia aren't the only ones suffering from his one-dimensional view of sovereignty. Often overlooked in the great game of international politics are the people who are bouncing back and forward on our seas. Our obsession with domestic integrity and control means that many desperately seeking our protection find themselves at greater risk. In today's world perhaps one of the greatest tests to traditional ideas on sovereignty is the idea of the responsibility to protect; to intervene when states are a threat to their own citizens. It's a controversial idea for obvious reasons. What's not so controversial is the responsibility to protect when citizens flee states and seek refuge, or, as in the case of the Rohingya, are effectively stateless. These are the people who in their final quest for freedom, safety, the faintest glimmer of a future, often turn to people smugglers and make perilous journeys across the seas in the first place. These are the people who we are increasingly turning away. And the more we doggedly assert our territorial integrity, the more we marginalise those who can't or don't have any borders to live within. As an Australian passionate about global affairs and human rights, this leaves me cold. I not only worry about how we will be remembered tomorrow, but how we can claim any meaningful place as a responsible nation on the world stage today. For once again our Prime Minister has shown his foreign policy hand isn't a winner. In this case he hasn't even got less Geneva, more Jakarta. He's simply got more Canberra and a healthy dose of "stuff ya". James Giggacher is editor of the specialist South-East Asia website New Mandala and an associate lecturer at the Coral Bell School of Asia Pacific Affairs, The Australian National University.
Q: JSON.Net - Use JsonIgnoreAttribute only on serialization (But not when deserialzing) We're using JSON.net and want to use a consistent way to send and receive data (documents). We want a base class that all documents will be derived from. The base class would have a DocumentType property - This is essentially the class name. When clients post this json-serialized document to the server, we want to deserialize it and ensure the DocumentType specified by the client matches the ExpectedDocumentType on the server. Then as well as this, when this document is serialized by the server and sent to the client, we want the DocumentType property included in the JSON - The trick is we want this value to be that of the ExpectedDocumentType. I've attempted to do this like so... This would work if the JsonProperty and JsonIgnore attributes only took affect during serialization but not deserialization however unfortunately that is not the case. public abstract class JsonDocument { /// <summary> /// The document type that the concrete class expects to be deserialized from. /// </summary> //[JsonProperty(PropertyName = "DocumentType")] // We substitute the DocumentType property with this ExpectedDocumentType property when serializing derived types. public abstract string ExpectedDocumentType { get; } /// <summary> /// The actual document type that was provided in the JSON that the concrete class was deserialized from. /// </summary> [JsonIgnore] // We ignore this property when serializing derived types and instead use the ExpectedDocumentType property. public string DocumentType { get; set; } } Does anyone know how to achieve this? Essentially the logic is that a client may provide any DocumentType so during deserialization the server needs to ensure this matches the ExpectedDocumentType, and then during serialization when the server sends this document to the client, the server knows the correct DocumentType so needs to populate it with the ExpectedDocumentType. A: Use the ShouldSerialize feature provided by Json.Net. So basically, your class will look like: public abstract class JsonDocument { /// <summary> /// The document type that the concrete class expects to be deserialized from. /// </summary> //[JsonProperty(PropertyName = "DocumentType")] // We substitute the DocumentType property with this ExpectedDocumentType property when serializing derived types. public abstract string ExpectedDocumentType { get; } /// <summary> /// The actual document type that was provided in the JSON that the concrete class was deserialized from. /// </summary> public string DocumentType { get; set; } //Tells json.net to not serialize DocumentType, but allows DocumentType to be deserialized public bool ShouldSerializeDocumentType() { return false; } }
Eating lunch with an iguana? Sipping lattes with a snake? It's nothing unusual at Pet Cafe in Hanoi, where rodents, reptiles and more are available for customers to handle and play with.
/** * Copyright (c) Facebook, Inc. and its affiliates. * * This source code is licensed under the MIT license found in the * LICENSE file in the root directory of this source tree. */ #import "ABI37_0_0RCTI18nManager.h" #import "ABI37_0_0RCTI18nUtil.h" @implementation ABI37_0_0RCTI18nManager ABI37_0_0RCT_EXPORT_MODULE() + (BOOL)requiresMainQueueSetup { return NO; } ABI37_0_0RCT_EXPORT_METHOD(allowRTL:(BOOL)value) { [[ABI37_0_0RCTI18nUtil sharedInstance] allowRTL:value]; } ABI37_0_0RCT_EXPORT_METHOD(forceRTL:(BOOL)value) { [[ABI37_0_0RCTI18nUtil sharedInstance] forceRTL:value]; } ABI37_0_0RCT_EXPORT_METHOD(swapLeftAndRightInRTL:(BOOL)value) { [[ABI37_0_0RCTI18nUtil sharedInstance] swapLeftAndRightInRTL:value]; } - (NSDictionary *)constantsToExport { return [self getConstants]; } - (NSDictionary *)getConstants { return @{ @"isRTL": @([[ABI37_0_0RCTI18nUtil sharedInstance] isRTL]), @"doLeftAndRightSwapInRTL": @([[ABI37_0_0RCTI18nUtil sharedInstance] doLeftAndRightSwapInRTL]) }; } @end
This invention relates to an induction system for an internal combustion engine and more particularly to an improved cylinder head and induction passage arrangement for a multiple valve internal combustion engine. It has been recognized that the performance of engines can be improved by increasing the number of valves serving each cylinder of the engine. Four valve per cylinder engines employing two intake valves per cylinder are now common practice, particularly in the automotive industry. However, it is also acknowledged that greater performance can be obtained through the use of three intake valves per cylinder. However, the use of three intake valves per cylinder does give rise to certain problems in that the flow through the three intake valves can cause interfering relationship within the cylinder under some conditions and can adversely affect performance. For example, in a normal three input valve engine there are provided a pair of side intake valves that are disposed on opposite sides of a first plane that lies on the cylinder bore axis and which are intersected or lie close to a second plane perpendicular to the first plane and also passing through the cylinder bore axis. A third or center intake valve is disposed on the first plane and is spaced further from the second plane than the pair of side intake valves. With this type of valve placement, the side intake valves can be disposed so as to generate a tumble action within the cylinder which has been found to promote performance, particularly under low and mid-range performance. This tumble action directs the charge into the cylinder in such a way as to cause a swirl about an axis that extends transversely to the cylinder bore axis and is thus distinguished from more conventional, axial swirl which occurs around the cylinder bore axis. It has been found, however, that the positioning of the center intake valve creates a reverse tumble action which obscures or reduces the tumble action which is generated by the side intake valves and can under some running conditions deteriorate engine performance. It is, therefore, a principal object of this invention to provide an improved induction system arrangement for an engine employing three intake valves per cylinder. It is a further object of this invention to provide a cylinder head and intake passage arrangement for a three intake valve per cylinder engine wherein the effects of tumble in low and mid-ranges can be maintained. In addition to the desirability of maintaining a tumble action in the cylinder under some running conditions, it is also desirable to employ a control valve for controlling the flow through the various intake valves. By doing this, it is possible to tune some of the intake passages to suit running conditions substantially different than those of the remaining valves. However, in order to do this, it is necessary to provide intake passages of different lengths and with previously proposed multi-valve constructions, this has not been easy to accomplish. It is, therefore, a still further object of this invention to provide a cylinder head and induction passage arrangement for a multi-valve engine wherein the passages can be configured so as to have substantially different lengths without interfering with each other and while still maintaining a compact construction. With the use of multi-valves and multiple intake passages to achieve the aforenoted result, it is the practice to provide at least one intake passage that is separate from the remaining intake passages that serve the cylinder. However, total isolation between the intake passages, particularly where one of them is throttled, can give rise to some performance defects in mid-range conditions where at the transition between the flow between only certain of the intake passages and flow between all of the intake passages. It is, therefore, a still further object of this invention to provide an improved cylinder head and intake passage arrangement for a multiple valve engine that will provide good performance throughout the entire engine speed in low ranges.
Like I've said, I rarely play competitive games online but I don't know if a day has gone by in the last few weeks where I haven't played at least one match of Rocketeague. Congrats guys and the new field looks awesome! Heard someone describe the old maps, one with pirate sails and such, and would love to see ones like that too if just for the novelty.
Q: Spring with spring.config.location I am trying to point at path to external configuration file like this: --spring.config.location=file: C:/Users/some_user/workspace/repository1/payment-api/payment.yml and it doesn't work. Any idea why? A: The proper prefix is file://. On Windows you need an extra "/" in the file URL if it is absolute with a drive prefix Try file:///C:/Users/some_user/workspace/repository1/payment-api/payment.yml instead.
The overall hypothesis is that the decline in physical activity habits and resultant increase in body fat reduces exercise capacity & muscle mass in military women. These lifestyle changes worsen metabolic & cardiovascular risk factors. Therefore continued involvement in resistance & endurance exercise programs which increases or preserves fat free mass,as well as enhances physical activity will prevent functional declines in military-eligible women.
Q: How do I change the ACLs on a registry key? (C++) I need to delete a regsitry key. It has a deny ACL on Set Value (I need this permission to delete it). How do I change the ACLs in C++? A: You could use RegSetKeySecurity to adjust the security settings and then delete the key as usual.
namespace ClassLib094 { public class Class014 { public static string Property => "ClassLib094"; } }
Launch of Student Digital Learning Hub by joeshortt The transition year Digital Champions team has developed a website called the Student Digital Learning Hub. The purpose of the website and the accompanying Android app is to provide information for all students in our school about digital technologies and resources which will help them with learning. This project is also designed to support the introduction of an ePortfolio solution in the school. The ePortfolio solution will be introduced in Transition Year and the team for this project is made up of transition year students. The Digital Learning Hub site uses the same platform (Google Sites) as the ePortfolio solution. The site will give information and advice from a student perspective on how to build an ePortfolio. The team is currently doing a pilot of eportfolio using Google Sites and their advice will be helpful to other students in the future. The team has built the site and Android app and are now promoting them. They will also, enable others to collaborate in adding content. The rationale is to give students a voice in promoting digital technologies in learning at our school and to collaborate in building a community of practice among students in effective use of technology in learning.
Everyone knows a turtle when he sees one. Turtles are easy to recognize by their shells. A baby turtle is born with a shell just the right size for its body. As the turtle grows, its shell grows too. The hard shells of most turtles are made up of a “bony box” covered by horny plates. A turtle can’t crawl out of its shell. The shell makes up much of a turtle’s skeleton, and is firmly attached to its body. Turtles are well-protected by their shells. Some turtles, such as the box turtle, can pull their heads, tails, and legs into their shell when frightened. Then, very few enemies can get at them. All turtles hatch from eggs. The mother turtle lays the eggs in a hole she has dug. She then leaves them. The sun’s warmth hatches the eggs in about two months. As soon as the baby turtles are hatched, they are on their own. They must be able to tend for themselves. – Dick Rogers A starfish is a star-shaped animal that lives on the bottom of the sea in bays and shallow water. Starfish eat clams and other shellfish by pulling the shells apart and pushing their stomach into the shells to digest the food. Starfish have a peculiar way of eating. The common starfish feeds mostly on shellfish, it especially likes to eat clams, oysters, and mussels. To open a clam shell, the starfish wraps its arms around it. Under each arm are rows of tube like feet that stick to the shell like suction cups. The starfish then pulls the two section of the clam’s shell assist with its powerful arms. A starfish’s mouth is under its body. As soon as a starfish has pulled open the clam, it opens its mouth, turns it stomach inside out and pushes it inside the clam’s shell and digests the clam’s soft body. Once the meat is finished, the starfish pulls back its stomach, leaving only an empty clam shell behind. Most starfish have five arms, but some have seven arms or more. If a starfish loose an arm, it can grow another. – Dick Rogers
A computer model to analyze the cost-effectiveness of hormone replacement therapy. This paper gives a detailed presentation of a computer model for evaluating the cost-effectiveness (CE) of hormone replacement therapy (HRT), describing the model's design, structure, and data requirements. The model needs data specified for costs, quality of life, risks, and mortality rates. As an illustration, the CE of HRT in Sweden is calculated. Two treatment strategies are evaluated for asymptomatic women: estrogen-only therapy and estrogen combined with a progestin. The model produces similar results compared with earlier studies. The CE ratios improve with the size of the risk reduction and generally with age. Further, estrogen-only therapy is associated with a lower cost per gained effectiveness unit compared with combined therapy. Uncertainty surrounding the long-term effects of HRT means that the CE estimates should be interpreted carefully. The model permits the inclusion of indirect costs and costs in added life-years, allowing the analysis to be made from a societal perspective, which is an improvement relative to previous studies.
Hillary Clinton Refuses to Comment on Spitzer’s Sex Scandal Hillary Clinton is refusing comment on New York Democrat governor, and Hillary Clinton super delegate, Eliot Spitzer’s admitted frequenting of a prostitute. This seems to be a situation that Hillary has somehow found her way into many, many times over her years in public life. Her “experience” must tell her not to comment on this situation. But Spitzer’s prostitution bust goes much deeper than just hiring a prostitute. He may be charged with federal crimes for wiring money across state lines for use in an illegal activity. This is far more serious than prostitution. I find it amusing that Hillary is going to sit idly by and not denounce what Spitzer has done. Clinton has been bashing Barack Obama for his ties to Tony Rezko, who this week went on trial for money laundering, conveniently forgetting that she has ties to Rezko also. Now one of her committed, soon to be incarcerated, super delegates is in serious trouble with the Feds, and she doesn’t feel the need to distance herself from him. Doesn’t she feel as though Spitzer should step down? Does she think this is a fire-able offence? Does she condone it by not calling for his resignation? Her silence leads to these questions. Voters need to know that she thinks this is not acceptable behavior. Or does she? The double standard continues.
Q: how to open specific Jframe as a main jframe? when I run the project compiler says BUILD SUCCESSFUL but not any window is appear. when I runt the project I want to start main_window as a default window. but I have no Idea how to setting up this. A: If you are creating a jar file (as I assume you will be doing from your previously deleted question), the main class would be specified by the jar file's manifest. e.g., the manifest file, named MANIFEST.MF could contain a line looking like: Main-Class: gui.main_window
Semiconductor devices use interconnect, which includes metal lines and contacts/vias, to provide connection between active and/or device devices with external contacts. Typically, the metal patterns of different metallization layers are electrically interconnected by vias. Semiconductor devices with interconnect circuits, according to current technology, may comprise eight or more levels of metallization to satisfy device connection and geometry requirements. There are challenges in forming interconnect for advanced device technologies.
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Q: Missing product data on Magento reports (bestseller, products ordered) although in database Yesterday I ran a modified XML export at the Sales -> Orders overview. During this process there was an error and now I have a reporting issue: My reports seem to be reset and all information prior to the export appears to be missing. However, everything works fine with the reports in the interval after the incident, so no unusual behaviour - topsellers etc. are shown like you would expect them to. The following reports are affected (not a complete list): Reports -> Products -> Bestsellers Reports -> Products -> Products Ordered Reports -> Customers -> Customers by Orders Total Reports -> Sales -> Tax However, for example this report works fine: Reports -> Shopping Cart -> [any] When going to Sales -> Orders I have a complete list of all sales ever done in the shop. Whichever order I open, there is all the required information available (e.g. products bought, subtotal, date etc.). I read that the Reports -> Products -> Bestsellers table is based on the sales_flat_order_item & sales_flat_order table. I checked these, all entries up to the first day of the shop are there. As far as I can tell, all shop history is available and no data has been deleted. I also tried Reports -> Refresh statistics (lifetime) but it had no effect. Does anybody know where else to look or what to check? A: After some database examination I discovered that in the table sales_flat_order_item the column "state" had Null everywhere whereas the column "status" was fine and had the right information. I updated the table via SQL SELECT * FROM sales_flat_order UPDATE sales_flat_order SET state = "processing" WHERE state is Null and refresehd the lifetime statistics in the backend (reports -> update statistics) and the reports now show everything correctly once more.
Q: Is a motor-generator set a reasonable way to get the purest waveform electricity? It looks like audiophiles go as far as installing separate powerlines to power their high quality audio systems. The motivation is that the amplifier and other hardware would run cleaner when the powersource provides cleaner waveform and with a separate powerline the amplifier will not be affected by various electrical devices run by other households. Let's not assess whether any audible difference can exist because that's highly subjective. I'm interested in the purest waveform of the powersource part. That separate powerline can be hit by lightning is also parallel to many other wires around it and so can be affected by processes in those wires is connected to a large grid which has tons of transient processes happening all the times so it doesn't really sound like a reliable best purest waveform source. Would a motor-generator set run on the original powerline be better? It looks like it doesn't care much about all those lightnings, parallel wires and the grid. How good is a motor-generator set for generating the purest waveform electricity? A: The "purest waveform" you want for noise-sensitive equipment is flat DC. The both simplest and best way to get it is a battery. Why? Any kind of AC needs rectification of some kind. Even a motor-generator with a standard DC generator produces a rectified sinusoidal current. You could use an unipolar DC generator, as it was done for ultra-low-voltage ultra-high-current DC applications as galvanic plating in the past. But even then, you have a second concern, and that's AC currents on ground. In your motor-generator the two machines are connected with a steel rod. It's not possible not to have at least some AC noise on the DC ground without replacing that one by glass fibre or something like that. Use a battery. Charge it if the device is not used. Medical equipment is sometimes designed that way. (It makes also the compliance testing simpler.)
An overview of venous thromboembolism prophylaxis. This symposium reviewed the risk factors and problems associated with venous thromboembolism in surgical patients, especially those patients having total hip replacement. The importance of venous thromboembolism prophylaxis was emphasized by a theoretical analysis indicating that venous thromboembolism in patients having hip replacement not only saves lives but is also effective. A discussion of the pharmacology of low-molecular-weight heparin (LMWH) included a review of its role, clinically and experimentally, in venous thromboembolism prophylaxis. Three of the discussants presented their favorable experiences with LMWH in reducing the incidence of venous thromboembolism in patients having hip replacement. It can be concluded that LMWH does reduce the incidence of venous thromboembolism in patients having hip replacement without causing an increase in blood loss. If its effectiveness and safety remain substantiated, LMWH may soon become the preferred agent for venous thromboembolism prophylaxis.
Q: Are listed in Where are specifications for 「constructor.prototype」 function Js() {}; var js = new Js(); js.constructor.prototype; //Js {} Js.prototype = {}; js.constructor.prototype; Object {} function Js() {}; var js = new Js(); js.constructor;//function Js() {} Js.prototype = {}; js.constructor;//function Js() {} The difference between constructor.prototype and constructor? Have been described in where behavior specification of about constructor.prototype? A: The constructor object only reference the function which made the object, while the prototype contain all the properties and methods that will be inherited form a object, including the constructor property itself.
The complex mutual connection between stroke and bone health. Both stroke and osteoporosis are prevalent conditions among the elderly. With increasing life expectancy across the world, despite better preventative measures, the incidence of both conditions is set to rise in the ageing populations. Alongside with sharing several common risk factors, the current evidence suggests that these conditions are risk factors for each other albeit more clear support for the effects of stroke on bone health. In this article, we present aetiopathophysiology of these two conditions and the current evidence of impact on each other particularly the impact of stroke on bone health. We also provide suggestions for improving bone health in people living with stroke based on the currently available evidence.
Bob Simon Bob Simon is the Principal Advisor to the Director for Energy, Transportation, and Resources in the White House Office of Science and Technology Policy. Jamil Smith Jamil Smith is a Senior National Correspondent with MTV News. Most recently, he was a Senior Editor at New Republic, where he wrote and edited columns and features for both print and digital. There, Smith also hosted the podcast INTERSECTION, which dealt with identity politics. Prior to that, he served as a segment producer for "The Rachel Maddow Show" and "Melissa Harris-Perry." Smith's bylines have also appeared in the Washington Post, Ebony.com, and theGrio. Previous stops include NFL Films, HBO Sports, CNN and the William Morris Agency.
Age and present and future perceived quality of life. Future expectations of quality of life and present evaluations of quality of life were measured in three age groups using four measures. Expectations were found to exceed present evaluations on all four measures. There was a significant correlation between age and the Faces Scale for future expectations. Age also related to differences between future expectations and present quality of life estimates. Expectations, the cognitive dimension of hope, merit more intensive study.
In semiconductor devices it is desirable to be able to control minority carrier lifetime i.e. the time in which an electron will recombine in a P type semiconductor region or a hole will recombine in an N type semiconductor region. A relatively low minority carrier lifetime permits a semiconductor device to have a relatively fast switching speed and in the case of a field effect transistor (FET) reduces the gain of the parasitic bipolar transistor. To reduce minority carrier lifetime, the literature conventionally teaches such processes as heavy metal doping or irradiation with electrons, x-rays, alpha particles, gamma rays or neutrons. As would be expected, a variety of advantages and disadvantages is associated with each of these lifetime-killing processes. In the case of neutron irradiation many of the practical disadvantages have been overcome. For example, the problem of residual long term radioactivity has been avoided by irradiating at an appropriate point during processing and the problem of inadvertent transmutation doping of the semiconductor material has been overcome by using certain radiation shielding. One of the difficulties that nonetheless remains in the long term stability of the neutron-induced crystalline damage. That is, in some cases the stability of the minority carrier lifetime induced by conventional neutron irradiation is unacceptably low. In an effort to analyze the source of this stability problem the present invention was discovered.
Regulating trust in pediatric clinical trials. The participation of minors in clinical trials is essential to provide safe and effective medical care to children. Because few drugs have been tested in children, pediatricians are forced to prescribe medications off-label with uncertain efficacy and safety. In this article, we analyze how the enrollment of minors in clinical trials is negotiated within relationships of mutual trust between clinicians, minors, and their parents. After a brief description of the problems associated with involving minors in clinical research, we consider how existing "relationships of trust" can be used as a place where the concerns of research subjects can be more fully discussed and addressed. Building on the tacit recognition of trust found in The European Clinical Trials Directive we make policy recommendations that allow for clearer, more ethically informed guidelines for enrolling minors in clinical research.
Q: Should I set foreign keys in Cassandra tables? I am new to Cassandra and coming from relational background. I learned Cassandra does not support JOINs hence no concept of foreign keys. Suppose I have two tables: Users id name Cities id name In RDBMS world I should pass city_id into users table. Since there is no concept of joins and you are allowed to duplicate data, is it still work passing city_id into users table while I can create a table users_by_cities? A: The main Cassandra concept is that you design tables based off of your queries (as writes to the table have no restrictions). The design is based off of the query filters. An application that queries a table by some ID is somewhat unnatural as the CITY_ID could be any value and typically is unknown (unless you ran a prior query to get it). Something more natural may be CITY_NAME. Anyway, assuming there are no indexes on the table (which are mere tables themselves), there are rules in Cassandra regarding the filters you provide and the table design, mainly that, at a minimum, one of the filters MUST be the partition key. The partition key helps direct cassandra to the correct node for the data (which is how the reads are optimized). If none of your filters are the partition key, you'll get an error (unless you use ALLOW FILTERING, which is a no-no). The other filters, if there are any, must be the clustering columns (you can't have a filter that is neither the partition key nor the clustering columns - again, unless you use ALLOW FILTERING). These restrictions, coming from the RDBMS world, are unnatural and hard to adjust to, and because of them, you may have to duplicate data into very similar structures (maybe the only difference is the partition keys and clustering columns). For the most part, it is up to the application to manipulate each structure when changes occur, and the application must know which table to query based off of the filters provided. All of these are considered painful coming from a relational world (where you can do whatever you want to one structure). These "constraints" need to be weighed against the reasons why you chose Cassandra for your storage engine. Hope this helps. -Jim
SPRINGFIELD, Ore. — Helping children a world away, a local charity raises money for a war-torn African nation. At the Springfield Faith Center, the City of Refuge International provides help for hundreds of kids in the Congo, giving them food, medicine and shelter Richard Kitumba, the president of City of Refuge, was born and raised … Continue reading »
The decision in this regard was taken by State Disaster Management at a meeting chaired by Chief Minister Pinarayi Vijayan. The authority issued necessary directives to the State Relief Commissioner to make the official declaration in this regard.
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Man Utd out of the Champions League, Nicky Butt arrested and Paul Scholes charged by FA Not the best week for the Man Utd faithful’s, being almost humiliated at Camp Neu, showing how far really “The Biggest club in the World” are from being the best on the planet. Lionel Messi is still one of the best players on the planet, showing the Man Utd players how to be the clinical finish and “edge” that Paul Pogba should be for his club, but sadly far from being in a team lacking the quality of the best. News today is also sad reading with the arrest of Nicky Butt and Paul Scholes being charged by the FA for gambling while playing. Butt who is in charge of the Manchester United academy is not helping Ole Gunnar Solskjaer and the club with that episode close to the result out there tonight. Paul Scholes who has earlier gone out and being critical about former manager David Moyes, Louis Van Gaal and recently talking down Jose Mourinho, made a strange decision to resign via text from his short stint at Oldham Athletic manager. Recent news about Scholes being charged by FA for gambling while playing, is really shocking if that is true, since he, on the field, and also of it has been the real “white prince” but as we all know a really hard player to come up against when playing. Sad week for Manchester United, and as we have seen the this project at Manchester United is far from being a finished article, probably being heavily helped by a very nice fixture list in the beginning and some very lucky moments a few weeks back. A good analysis from Liam Brady and his party after the game, talking Man Utd after the defeat, getting everything right as the team is cleaned naked by Barcelona. They need to find a new momentum to be competitive. The big question will be, will Ole Gunnar Solskjaer, with his permanent job, put all smiles back on the Man Utd fans when they are up against the best teams and the best opponents like Barcelona and Lionel Messi. We honestly believed that Jose Mourinho probably was, maybe together with Jurgen Klopp, Carlo Ancelotti and Pep Guardiola, the only managers to get Manchester United back on track, but Ole Gunnar Solskjaer might get lucky again. They were in the Champions League and the FA Cup with Jose Mourinho at the helm, they were sixth in the Premier League, at the moment they are out of the Champions League, not in the FA Cup and still number six in the Premier League.
In the movie, television, and audio/video production industry, directors often give instructions for the editing of audio/video clips, such as scenes in movies. Such instructions were previously written or typed independently of the video clip to which they referred. The technicians following the instructions had to determine the times in the clip to which a given instruction was meant to apply based on the typed or written notes themselves. In order for the technicians to determine to which part of a clip an instruction referred, the written or typed instructions had to include the times within the clip that each instruction applied to. These notes had to be meticulous in order to avoid expensive editing mistakes. Taking careful notes of these times made annotating video clips more complicated, however, notes made without accurate time notations increased the chances of misunderstanding between the director and the technicians. Such misunderstandings lead to wasted time for both the technicians and directors. Accordingly, a video annotating system that automatically keeps track of annotations for film clips and stores the information in an accessible way would be useful.
The invention generally relates to block copolymer membranes. More particularly, the invention relates to zwitterion-functionalized block copolymer membranes. Porous polymeric membranes, either in hollow fiber or flat sheet configurations may be employed in many applications, such as, hemodialysis, ultrafiltration, nanofiltration, reverse osmosis, gas separation, microfiltration, and pervaporation. For many of these applications, membranes with optimal selectivity as well as chemical, thermal and mechanical stability are desirable. In many applications (for example, bio-separation or water filtration) it may also be desirable to have membranes with one or more of improved hydrophilicity, improved biocompatibility, or low fouling. Polyarylene ethers, in particular, polyethersulfones and polysulfones are often used as membrane materials because of their mechanical, thermal, and chemical stability. However, these polymers may not have the optimal biocompatibility and hydrophilicity for many applications. Further improvements in membrane hydrophilicity have been achieved by polymer blending, for example, fabricating the porous membrane in the presence of small amounts of hydrophilic polymers such as polyvinylpyrollidone (PVP). However, since PVP is water-soluble it is slowly leached from the porous polymer matrix creating product variability. Alternatively, hydrophilicity has been achieved via functionalization of the polymer backbone and introduction of carboxyl, nitrile or polyethylene glycol functionality, which may also provide chemical resistance and good mechanical properties. However, these chemical modifications may be complicated, expensive and inefficient. Thus, porous membranes having one or both of optimal hydrophilicity and biocompatibility are desired. Further, polymers capable of being fabricated into hydrophilic porous membranes polymers are also desired.