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1. A process of controlling a biochemical process (II) or biochemical cascade (III) of interest in a plant, said process comprising: (a) introducing into the nuclear genome of the plant one or more first heterologous DNA sequences; and (b) infecting the plant with at least one viral transfection vector containing in it...
<SOH> BACKGROUND OF THE INVENTION <EOH>Controllable Transgene Expression Systems in Plants One of the major problems in plant biotechnology is the achievement of reliable control over transgene expression. Tight control over gene expression in plants is essential if a downstream product of transgene expression is grow...
<SOH> BRIEF DESCRIPTION OF THE FIGURES <EOH>FIG. 1A is a schematic representation of a process according to the invention. FIG. 1B is a schematic representation of possible classes of processes of interaction in an infected plant cell. FIG. 2 depicts crTMV-based vectors pIC1111 and pIC1123 containing IRES cp,148 CR -A...
Orbital implant
An orbital implant includes a body of bioactive material having macropores of at least 400 μm, and a cap of bioactive material having substantially no pores or only micropores smaller than 50 μm. The cap covers a portion of the body.
1. An orbital implant which includes a body of bioactive material having macropores of at least 400 μm, and a cap of bioactive material having substantially no pores or only micropores smaller than 50 μm, with the cap covering a portion of the body. 2. An implant according to claim 1, which is substantially spherical. ...
Bumper airbag and system
An airbag (10) for mounting in the bumper (18) of a motor vehicle (12) is provided. The airbag can have an up-side-down “L” shape or a cylindrical shape. Further, multiple bags can be combined within one system. The airbag is configured to cover substantially the width of the vehicle upon deployment and also provide pr...
1. A bumper airbag system comprising: a housing disposed in the bumper of a first vehicle and having a frangible door; a sensor for determining a pending collision between the first vehicle and another object and generating a signal thereof; at least one inflator for dispensing inflation fluid in response to the signal...
<SOH> BACKGROUND OF THE INVENTION <EOH>For years, the automotive industry has tried various methods and products to reduce the damage to passengers and vehicles in collisions. Of prime importance are the various systems of vehicle airbags that are deployed upon the sensing of an actual collision. These airbags are loc...
<SOH> SUMMARY OF THE INVENTION <EOH>An advantage of the present invention is that it can reduce the severity of a collision between high standing vehicle and a low standing vehicle. Another advantage of the present invention is that it offers protection to the occupant of the struck vehicle in the event the occupant i...
5-azido-laevulinic acid, method for the production thereof and its use
The present invention relates to 5-azido levulinic acid, a process for its preparation, its use. Using 5-azido levulinic acid as starting material for the synthesis of 5-amino levulinic acid hydrochloride it is possible to obtain the latter in good yield an in pharmaceutical acceptable quality. 5-Azido levuliniv acid i...
1. 5-azido levulinic acid 2. Process for the preparation of 5-azidolevuliniv acid, wherein (a) methyl 5-bromo levulinate and/or methyl 5-chloro levulinate is converted with aqueous hydrochloric acid and as a result of an incomplete bromine/chlorine exchange at the C-5-postion a mixture of 5-chloro levulinic acid and 5-...
Medical metal implants that can be decomposed by corrosion
An in vivo, decomposable medical implant is provided and comprises a metal material that contains, as a main alloying constituent, tungsten or a metal from the group rhenium, osmium, and molybdenum. The method for decomposing the implant, via corrosion in a bio system, includes the step of changing the pH level of the ...
1-11. (cancelled) 12. An in vivo, decomposable medical implant from the group including: stents (coronary stents, peripHeral stents, tracheal stents, bile duct stents, esopHagus stents), surgical clips, osteosynthesis material, biological matrix (foam), metal wiring, metal threads, active substance depots, comprising a...
Piezoelectric actuator
An apparatus for actuating a brake comprising force transmission means for transmitting force to a friction pad of a brake, at least one piezo-electric device operable when energised to change shape and/or size so as to apply a force to the force transmission means in a direction for actuating the brake, and retaining ...
1. An apparatus for actuating a brake comprising: a force transmission means that transmits force to a friction pad of a brake; at least one piezo-electric device operable when energized to change at least one of shape and size so as to apply a force to the force transmission means in a first direction for actuating th...
Autonomous bird predation reduction device
A self-guided apparatus for repelling birds through various means of deterrence. The device comprises a chassis, a floatation assembly, a propulsion system, and a guidance and control system. The device may operate in either of at least two modes: passive and active. In the passive mode, the device traverses a predefin...
1. A device for traversing a water body and for reducing the number of birds in the vicinity of the water body, said device comprising: (a) one or more floats having sufficient buoyancy to maintain a portion of said device above the surface of the water body; (b) an electrically-powered propulsion system adapted to tra...
<SOH> BACKGROUND ART <EOH>Bird depredation of fish, crawfish, and shrimp in aquaculture ponds poses major problems. For example, pelicans can consume 1 to 3 lb (0.45 to 1.36 kg) of fish per day, and may arrive with hundreds per flock. Cormorants, anhingas, herons, and egrets may also do significant damage to aquacultu...
<SOH> BRIEF DESCRIPTION OF THE FIGURES <EOH>FIG. 1 illustrates a front plan view of one embodiment of the predation reduction device. FIG. 2 illustrates a perspective view of one embodiment of the predation reduction device with the solar panels removed. FIG. 3 is an illustrative trajectory diagram depicting typical p...
Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step...
1. A method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, wherein the plural capture oligonucleotide probes have melting temperatures within a narrow range, said method comprising: providing a first set ...
<SOH> BACKGROUND OF THE INVENTION <EOH>Detection of Sequence Differences Large-scale multiplex analysis of highly polymorphic loci is needed for practical identification of individuals, e.g., for paternity testing and in forensic science (Reynolds et al., Anal. Chem., 63: 2-15 (1991)), for organ-transplant donor-recip...
<SOH> SUMMARY OF THE INVENTION <EOH>The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures ...
Lactic acid bacteria overproducing exopolysaccharides
The invention concerns lactic acid bacteria overproducing exopolysaccharides following mutation in the gene coding for α-phosphoglucomutase. Said mutants are useful, in particular for preparing fermented products or for producing exopolysaccharides.
1. A lactic acid bacteria mutant overproducing exopolysaccharides, in which the pgm gene of alpha-phosphoglucomutase is totally or partially inactivated. 2. The mutant as claimed in claim 1, in which the galU gene is overexpressed. 3. The mutant as claimed in either one of claims 1 and 2, characterized in that said lac...
Method for measuring cylinder specific parameters in a combustion engine
The invention concerns a method to measure parameters in the combustion chamber of a piston engine that comprises an ignition system. An alternating voltage is applied across the secondary winding of the ignition coil and the value of the current that arises in a measurement circuit that co-operates with the secondary ...
1. A method to measure and determine cylinder-specific parameters such as pressure, piston position and impedance in a combustion chamber of a piston engine having an ignition system with an ignition coil and spark plugs, characterised in that measurement occurs with the aid of the ignition system through the applicati...
<SOH> TECHNICAL FIELD <EOH>The present invention concerns a method for measuring and determining cylinder-specific parameters in a combustion chamber in a piston engine that comprises an ignition system.
<SOH> SUMMARY OF THE INVENTION <EOH>The method of measuring and determining cylinder-specific parameters in a combustion chamber of a piston engine that comprises an ignition system is characterised in that the measurement occurs with the aid of the ignition system in that an alternating voltage is applied across the ...
Method and device for the mechanical-thermal separation of different materials
The invention relates to a method and system for the mechanical-thermal separation of different materials such as textile flat structures, threads, and plastic films by heating and simultaneously compacting the material. According to the invention, the material is fed through a gap which is formed between a tool (2) an...
1. Method for the mechanical/thermal severing of different materials, such as textile fabrics, yarns and plastic films by heating and simultaneously compacting the material, the material being passed in the transporting direction through a gap, which is closed at one end and formed between a tool and a counter surface,...
Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
The present invention is directed to compounds of the formula I: Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the broken lines are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
1. A compound of formula I: wherein: X is selected from the group consisting of: C, N, O, S and SO2; Y is N or C; R1 is selected from the group consisting of: hydrogen, —C1-6alkyl, —C0-6alkyl-O—C1-6alkyl, —C0-6alkyl-S—C1-6alkyl, —(C0-6alkyl)-(C3-7cycloalkyl)-(C0-6alkyl), hydroxy, heterocycle, —CN, —NR12R12, —NR12COR13,...
<SOH> BACKGROUND OF THE INVENTION <EOH>The chemokines are a family of small (70-120 amino acids), proinflammatory cytokines, with potent chemotactic activities. Chemokines are chemotactic cytokines that are released by a wide variety of cells to attract various cells, such as monocytes, macrophages, T cells, eosinophil...
<SOH> SUMMARY OF THE INVENTION <EOH>The present invention is further directed to compounds which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinit...
Production of high grade and high concentration of free fatty acids from residual residual oils, fats and greases
The present invention relates to a process for the production of unsaturated and saturated free fatty acids. The process comprises the steps of: (a) selecting a starting material from the group consisting of trap oils, trap greases, yellow greases and brown greases, (b) pre-treating the oils and/or greases selected in ...
1. A process for producing unsaturated and saturated free fatty acids, the process being characterized in that it comprises the steps of: a) selecting a starting material from the group consisting of trap oils, trap greases, yellow greases and brown greases, b) pre-treating the oils and/or greases selected in step a) i...
<SOH> BACKGROUND OF THE INVENTION <EOH>Most commercial unsaturated acids (i.e. oleic acid) are derived from animal tallow (by-product of the meat industry), tall oil (by-product of paper mills) or natural vegetable oils. Fat splitting processes are well known in the art. The most common methods are: 1) Twichell proces...
<SOH> SUMMARY OF THE INVENTION <EOH>An object of the present invention is to provide a process for the production of free fatty acids that uses residual oils, fats and greases as the starting material. Another object of the present invention is to provide an inexpensive and simple way to produce high grade and high co...
Micro-arrayed organization of transcription factor target genes
The following invention outlines methodologies for the construction and utilization of transcription factor direct target gene microarrays of both DNA and corresponding protein/peptide target origin. The technology entails the array/microarray annotation and organization of transcription factor direct loci and correspo...
1. A method according to the present invention which utilizes modified sequential chromosomal immunoprecipitation and cloning procedures for the discovery of transcription factor target genes from cells whereby said genes are organized into an array format. 2. A method according to claim 1 comprising the process of: a)...
<SOH> 2.0 BACKGROUND OF THE INVENTION <EOH>Genetic activity, i.e. the activation or repression of gene transcription, has long been directly correlated with gene function. Transcriptional regulation is the first and perhaps most crucial mechanism by which cells regulate the functions of genes. By providing or denying ...
<SOH> 3.0 SUMMARY OF THE INVENTION <EOH>The application of array and microarray technologies for purposes of assessing genetic as well as biochemical interaction profiles of sample populations has been considerably limited by the construction of both nucleotide and peptide or protein arrays which do not represent disc...
Eeg feedback controlled sound therapy for tinnitus
An automated method for treating tinnitus by habituation through use of neurological feedback, comprising the steps of connecting a subject through a set of attached headphones to an electronic sound player that is connected to a PC workstation presenting sound examples by software to the subject who can refine them by...
1. An automated method for treating tinnitus by habituation to customized sound through use of neurological feedback, comprising the steps of: connecting a subject through headphones to an electronic sound player that is connected to a PC workstation; creating a customized sound profile for the subject's particular tin...
<SOH> BACKGROUND OF THE INVENTION <EOH>1. Field of the Invention The present invention generally concerns the diagnosis and treatment of tinnitus. The invention more specifically relates to the use of custom designed sound and feedback to determine the precise treatment sound matching the tinnitus, its neurophysiologi...
<SOH> SUMMARY OF THE INVENTION <EOH>To address the beforementioned problem and the above solution the inventors disclose their invention as follows. The invention contemplates an automated method for treating tinnitus by habituation to customized sound through use of neurological feedback. The methodology comprises th...
Method for applying a layer containing at least polymeric material
In a method for applying a layer containing at least polymer material to a substrate, there is applied to the substrate a film of polymer particles dispersed in a non-reactive liquid. By subjecting these at least polymer material-containing particles to an energy flow, which is locally at least substantially converted ...
1. A method for applying a layer containing at least polymer material to a substrate, wherein the layer is obtained by applying, to the substrate, a film including at least polymer material-containing particles dispersed in a non-reactive liquid, and subjecting the particles to an energy flow which is locally substanti...
Optical recording medium and its manufacturing method
A multi-layered film made of sequentially stacked first dielectric layer, recording layer, record-assist layer, second dielectric layer and first reflection layer on a disc substrate having a concavo-convex structure at least on one surface thereof. An ultraviolet-setting resin layer is formed to cover the multi-layere...
1. An optical recording medium comprising: a disc substrate having formed a concavo-convex structure formed at least on one surface thereof; and a multi-layered film made by stacking at least a recording layer capable of recording information signals by irradiation of a laser beam and a record-assist layer adjacent to ...
<SOH> BACKGROUND ART <EOH>Recently, along with enhancement of recording density of optical recording mediums such as optical discs, development of the technique of effectively using the area on the recording surface of an optical disc has been pushed forward to enhance the recording density. The recording surface of a...
<SOH> BRIEF DESCRIPTION OF DRAWINGS <EOH>FIG. 1 is a cross-sectional view that shows an optical disc according to the first embodiment of the invention FIG. 2 is a graph that shows dependency or a carrier upon the thickness of a record-assist layer in the optical disc according to the first embodiment of the invention...