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Statistical analysis
v.26.0
Statistical analyses were performed using SPSS v.26.0 (SPSSInc. Chicago, IL). Results are expressed as mean ± SD. Data distribution was examined for normality using the Shapiro–Wilk test and results revealed that all the variables presented a normal distribution of the data. A mixed-measures analysis of variance (ANOVA...
PMC10681300
Results
Nutritional intake is showed in
PMC10681300
Nutritional intake of Spanish elite soccer players (mean ± SD) and current recommendations [
Tomas
*% of E: percentage of total energy intake**Recommendation: current recommendations for daily average intake. NA: not applicable. (Tomas et al., 2016; Ranchordas et al., 2017; FESNAD, 2015)*** For the weekdays, the mean intake across the five days was used for analysis[NK was classified as “average” knowledge (60–61%) ...
PMC10681300
Effects after both EG and CG interventions on anthropometrical and physical parameters.
(A) Body mass; (B) Skinfolds sum (mm); (C) Vertical jump height (cm); (D) 20 m sprint time (s). ***, Significant (p < 0.001); **, Significant (p < 0,01) differences between pre- and post—test measurements.Biochemical variables are displayed in
PMC10681300
Changes (mean ± SD) in biochemical variables for the CG (n = 10) and EG group (n = 9) before (PRE) and after intervention (POST).
P value for the comparison between pre- and post-intervention values by Bonferroni test, and effect size (ES) for the changes, the magnitude of change (%), as well as the reference values are shown for each group.Abbreviatures: EG, Exchanged-diet group; CG, Controlled-diet group.*, Significant (p < 0.05) differences be...
PMC10681300
Discussion
metabolic and neuromuscular response, eating disorders, injuries, anemia
ANEMIA
Given the growing popularity of women’s soccer, its physically demanding nature and the high incidence of injuries, various approaches to optimize performance and decrease injury risk and severity have been explored in the scientific literature. Athletes need to consume enough energy to ensure an effective metabolic an...
PMC10681300
Supporting information
PMC10681300
This is the adherence questionnaires.
(DOCX)Click here for additional data file.
PMC10681300
This is the translation of adherence questionnaires.
(DOCX)Click here for additional data file.
PMC10681300
This is the database of
(XLSX)Click here for additional data file.
PMC10681300
This is the global database.
(XLSX)Click here for additional data file.
PMC10681300
Abstract
TESTICULAR CANCER
This randomized controlled trial study aims to examine the flipped classroom model's effects on the knowledge and health beliefs of testicular cancer and testicular self-examination. The study was conducted on 66 students in Northern Cyprus. A descriptive information form, Champion’s Health Belief Model Scale, visual a...
PMC10655630
Introduction
HBM, Testicular cancer, malignant cancers, TC, cancer
TESTICULAR CANCER, DISEASE, CANCER
Testicular cancer (TC) accounts for 1.0–1.5% of all malignant cancers, and the incidence of the disease is higher in males aged 15–35 years [Although the TC cells spread rapidly, the 5-year survival rates of the patients may increase up to 95% if diagnosed early [Different psychosocial models explain the attitudes and ...
PMC10655630
Method
PMC10655630
Study design and setting
This randomized controlled trial was conducted at the department of nursing of a university in Northern Cyprus during the fall semester of the 2020–2021 academic year. In this study, the researcher followed the randomized controlled studies using the Consolidated Standards of Reporting Trials 2015 control list.
PMC10655630
Sampling
G-Power 3.1.9.2 was used to calculate the sample size. A total of 42 participants, 21 participants in each of the two groups, were required for a 95% confidence interval, 80% power and 0.8 effect size. In this study, Cohen’s d effect size was used to calculate the effect size of two independent groups [
PMC10655630
Randomization and blinding
A simple randomization method was used to allocate the participants into two groups with equal numbers. The intervention group (The Consolidated Standards of Reporting Trials (CONSORT) 2010 flow diagram of the participants through each stage of the study.
PMC10655630
Data collection tools
A descriptive information form, a knowledge questionnaire on TC and TSE and the Champion’s Health Belief Model Scale (CHBMS) were used for data collection.
PMC10655630
Descriptive information form
This form consisted of 11 questions, including 2 questions on sociodemographic characteristics (age and marital status) and 9 questions on the characteristics of TC and TSE, such as individual and family history, perceived TC risk, level and source of knowledge, regular TSE performance and the reasons for not performin...
PMC10655630
Knowledge questionnaire on TC and TSE
This questionnaire contained 16 questions on the frequency and risk factors of TC, the importance of the early diagnosis of TSE and the frequency and method of TSE. The participants were asked to respond to each question on a three-point Likert scale, with the possible responses being ‘yes’ (1 point), ‘no’ (0 points) a...
PMC10655630
CHBMS
The CHBMS was developed by Barnes (2000) and translated into Turkish by Pınar
PMC10655630
Interventions
Data were collected online from December 2020 to March 2021 via Google Forms survey software. Due to the Covid-19 pandemic at the time of the study, all training sessions were conducted online in our country, so this study was carried out entirely online. After obtaining the necessary permissions, the participants were...
PMC10655630
Outcomes
The knowledge questionnaire on TC and TSE and the CHBMS were used to evaluate the knowledge and health awareness concerning TC and TSE amongst male nursing students. The VAS was used to evaluate student satisfaction with the FCM.
PMC10655630
Statistical analysis
The collected data were analysed using the Statistical Package for Social Sciences (SPSS) version 24.0 (IBM, Armonk, NY, USA). Descriptive characteristics of the participants were presented by the frequency of the responses. Descriptive statistics, including mean, standard deviation and minimum and maximum values, were...
PMC10655630
Ethical considerations
Permission was obtained from the Scientific Research and Publication Ethics Committee (ETK00-2020-0279) and the institution to conduct the study. Written informed consent was obtained from all participants.
PMC10655630
Results
The comparison of some of the descriptive characteristics of the two groups can be seen in Intergroup comparison of the descriptive characteristicsFisher’s exact test.Next, the comparison of the scores obtained from the knowledge questionnaire and the subscales of the CHBMS is presented in Pretest scores obtained from ...
PMC10655630
Discussion
HBM
Despite high cure rates, TC continues to pose a serious threat, especially to young adult men. Testicular self-exam is the primary health-protective behaviour in the early diagnosis and treatment of TC. In this study, the majority of the participants did not know about TC and did not perform TSE regularly prior to the ...
PMC10655630
Conclusion
Sustaining educational activities to improve awareness of TC and TSE in university students aged 18–35 years is vital. Although the scores obtained by the groups in our study increased after the course on TC and TSE, participants in the intervention group, who received a lecture based on flipped classroom methods, had ...
PMC10655630
Author contributions
Kamil Akcali (Study design, Data analysis, Manuscript preparation) and Sevinc Tastan (Study design, Data analysis, Manuscript preparation).
PMC10655630
Funding
None declared.
PMC10655630
Conflict of interest statement
None of the authors have personal or financial relationships which influence the study.
PMC10655630
References
PMC10655630
Purpose:
In this study, the aim to assess the combined effects of prone-positioning (PP) and minimal-flow (MF) general anesthesia on regional cerebral oxygenation (RCO) and systemic hemodynamics.
PMC10042492
Methods:
This is a randomized prospective study aiming to evaluate changes in cerebral oxygenation and hemodynamic parameters in MF systemic anesthesia in patients undergoing surgery in PP. Patients were randomized to MF or normal-flow (NF) anesthesia. In the operating room, pulse rate, mean arterial pressure (MAP), peripheral ...
PMC10042492
Results:
Overall, 46 patients were included (24 in the MF group and 22 in the NF group). The amount of anesthetic gas consumption was significantly lower in the low-flow (LF) group. In both groups, the mean pulse rate showed a decrease after PP. Before induction, RCO was significantly higher both at the right- and left-sides in...
PMC10042492
Conclusions:
MF anesthesia in PP did not reduce cerebral oxygenation compared to NF and was safe in terms of systemic hemodynamics and cerebral oxygenation.
PMC10042492
Key words
PMC10042492
Introduction
hypoxia
HYPOXIA, ACUTE RESPIRATORY DISTRESS SYNDROME, COMPLICATIONS
The rate of utilization of low-flow (LF) anesthesia has gradually increased during the last decade, owing to some clinical advantages and cost savings. First suggested by Baum and AitkenheadActually, the most vulnerable organ to anesthesia-induced hypoxia is the brain. Thus, monitoring of cerebral oxygenation under var...
PMC10042492
Material and Methods
PMC10042492
Design, participants, and setting
DISEASE
This was a randomized prospective comparative study that aimed to evaluate the likely changes in cerebral oxygenation and hemodynamic parameters with the use of minimal fresh gas flow systemic anesthesia in patients undergoing surgery in a PP. The study protocol was approved by the local ethics committee decision no: 1...
PMC10042492
CONSORT flow diagram.
PMC10042492
Anesthesia protocols
Patients were randomly allocated to either minimal fresh gas flow (MF, 0.5 L/min during maintenance) or normal-flow (NF, 2 L/min) general anesthesia. In both groups, participants were first administered with 100% oxygen at a 4 L/min flow rate. Propofol 2–2.5 mg/kg, rocuronium bromide 0.6 mg/kg, and fentanyl 1 mcg/kg IV...
PMC10042492
Monitorization and data collection
Age, sex, body mass index, ASA class, preoperative opioid consumption, duration of surgery, duration of general anesthesia, duration of PP, type of surgical procedure, and the total amount of consumed inhaled anesthetic were recorded for all study participants.In the operating room, pulse rate, mean arterial pressure (...
PMC10042492
Statistical analysis
Power:0.80
The Shapiro–Wilk test and O-O plot were used to assess the normality. While continuous variables were presented as mean ± standard deviation or median (min-max) depending on the distribution of the variable, categorical variables were presented as numbers and %. Depend on the results of the normality test, the Mann–Whi...
PMC10042492
Results
POSTERIOR FOSSA TUMOR
A total of 46 patients (50% females) were randomized to either MF fresh gas (24 patients) or NF (22 patients) anesthesia. The mean age of the whole study group was 50.3 ± 15.1 years. Fourteen operations (30.4%) were performed by orthopedists, while 32 operations (69.6%) were carried out by neurosurgeons. All of the ort...
PMC10042492
Surgical and anesthetic features
ASA physical status classes were similar between MF and NF anesthesia groups. MF and NF anesthesia were regularly distributed over surgical departments and procedure types. Duration of anesthesia and surgery lasted significantly longer in the MF anesthesia group than in the NF anesthesia group. As a consequence, PP dur...
PMC10042492
Comparison of minimal-flow and normal-flow anesthesia patients in terms of clinicodemographic characteristics, surgery, and anesthesia features.
PMC10042492
Monitorization parameters
PMC10042492
Pulse rate
In both MF and NF groups, the mean pulse rate showed a decrease after PP. However, there was no difference between MF and high flow (HF) groups in this regard. After the resumption of supine posture, mean pulse rates increased slightly in both groups, but there was no difference between the groups again (
PMC10042492
Comparison of pulse rate, mean arterial pressure, minimal alveolar concentration, and end-tidal carbon dioxide during measurement time points.
PMC10042492
Mean arterial pressure (MAP)
Baseline MAPs were different before anesthesia induction between the groups (102.6 ± 15.0 mmHg in the MF group and 113.5 ± 15.3 mmHg in the NF group, p = 0.019). After, PP blood pressure decreased significantly in both groups. However, MAP remained to be significantly higher in the NF group compared to the MF group. In...
PMC10042492
End-tidal carbon dioxide (EtCO
EtCO
PMC10042492
Peripheral oxygen saturation (SpO
Peripheral oxygen saturation increased from 98% to 100% after PP in the MF group. Throughout the operation, including post-extubation status, spO
PMC10042492
Comparison of peripheral oxygen saturation, and right and left side regional cerebral oxygenation during measurement time points.
PMC10042492
Regional cerebral oxygenation (measured by NIRS)
At baseline evaluation before anesthesia induction, RCO was significantly higher both at the right and left sides in the MF group compared to the NF group. This difference continued throughout the operation on the left side. However, this difference disappeared 10 min after intubation on the right side. Placing the pat...
PMC10042492
Left-sided cerebral oxygen saturation measurements during study time-points.
PMC10042492
Right-sided cerebral oxygen saturation measurements during study time-points.
PMC10042492
Discussion
hypoxia, Left-sided regional cerebral oxygen, Kupisiak
HYPOXIA, SECONDARY
The purpose of the study to evaluate the impact of MF inhaled anesthesia coupled with PP on cerebral oxygenation and hemodynamic parameters. The major findings of the present study can be summarized as follows: 1) Anesthetic gas consumption was significantly lower in the MF anesthesia group; 2) PP decreased pulse rate ...
PMC10042492
Conclusion
For the first time in the literature, this study evaluated the impact of PP along with MF anesthesia on systemic hemodynamics and RCO. The results of the present study revealed that MF anesthesia in patients undergoing surgery in the prone position did not cause a reduction in cerebral oxygenation compared to NF. PP al...
PMC10042492
References
PMC10042492
Background
postoperative pain, palmar hyperhidrosis, pain
Although thoracoscopic sympathectomy is made via small incisions, it is associated with severe postoperative pain. Both Rhomboid intercostal block (RIB) and serratus anterior plane block (SABP) are recent techniques used for pain control after such procedures. Herein, we compared RIB and SAPB regarding pain control in ...
PMC10355006
Patients and methods
Three groups were enrolled in this prospective randomized study (71 patients in each group); Group S received SAPB, Group R received RIB and Group C as controls. The block procedures were performed after general anesthesia and prior to the skin incision.
PMC10355006
Results
The three groups showed comparable demographics and operative time (
PMC10355006
Conclusion
hyperhidrosis, pain
Both RIB and SAPB are safe and effective in pain reduction after thoracoscopic sympathectomy procedures in patients with hyperhidrosis. Moreover, RIB is superior to SAPB as it is associated with better analgesic outcomes.
PMC10355006
Trial registration
Pan African Trial Registry PACTR202203766891354.
PMC10355006
Keywords
Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB).
PMC10355006
Introduction
postoperative pain, Primary palmar hyperhidrosis, anxiety, Postoperative pain, chest pain, pain, infection, paraspinal muscular pain, hematoma
DISORDER, INFECTION, HEMATOMA, ABSENCE OF SWEATING
Primary palmar hyperhidrosis is a disorder characterized by chronic excessive sweating despite the absence of sweating triggers. With the evolution of surgical approaches, upper thoracic dorsal sympathectomy performed via video-assisted thoracoscopic surgery (VATS) is the main management option for that clinical entity...
PMC10355006
Patients and methods
infection, psychiatric, hyperhidrosis
INFECTION, BLEEDING DISORDERS
This prospective randomized controlled parallel study was conducted over one year, starting from March 2022 to March 2023, at Mansoura university hospitals after the Institutional Research Board and ethical committee of our university (MFM-IRB) approval (R.21.09.1462) on 31/10/ 2021. The study was designed for 213 pati...
PMC10355006
Randomization and blinding
pain
A total of 213 patients were randomly assigned to three equal groups using a computer-generated table of random numbers: Group R included patients who received RIB, Group S included patients who received SAPB, and Group C included the remaining patients who received no block procedure. The group allocation was conceale...
PMC10355006
Patient's data
serratus anterior block, pain
HEART
At the operative theater, all patients were sedated by IV midazolam 2 mg, and standard monitoring was applied. General anesthesia was induced by IV propofol, atracurium, and fentanyl with doses of 2.5 mg/kg, 0.5 mg/kg, and 1 μg/kg, respectively. A single-lumen endotracheal tube was used. All patients were kept on press...
PMC10355006
Collected data
pain
SECONDARY, COMPLICATIONS
The primary outcome was the time to the first rescue analgesic, whereas secondary ones included intraoperative hemodynamic changes, pain scores, postoperative opioid consumption, the incidence of complications, and patient satisfaction.
PMC10355006
Statistical analysis
Statistical analysis was performed by the SPSS (version 21.0; SPSS Inc, Chicago, Ill, United States) software program. Numerical data were expressed as mean and standard deviation and compared between the three groups using the one-way ANOVA test. The categorical ones were expressed as numbers and percentages and compa...
PMC10355006
Discussion
postoperative pain, ESPB, Postoperative pain, chronic postoperative pain, pain
CHRONIC POSTOPERATIVE PAIN, INFILTRATION
The current study demonstrates that both RIB and SAPB were effective techniques in providing analgesia for patients undergoing VATS. RIB and SAPB were performed before the skin incision, "preemptive analgesia," to induce better analgesia compared to blocks performed after surgery owing to its protective effect on the h...
PMC10355006
Acknowledgements
We acknowledge the Egyptian K knowledge Bank- Enago for providing proof reading of the article.
PMC10355006
Author’s contributions
M.G.E., principal investigator, formulated the research, study design, data acquisition, and interpretation and drafted the manuscript. K.M.E., M.S.E., helped in the study design and revising of the final manuscript. All authors approved the final manuscript.
PMC10355006
Funding
Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB). We did not receive any specific funds. We only used institutional resources.
PMC10355006
Availability of data and materials
The individual participant data will be available upon reasonable request with the corresponding author after the local IRB approval.
PMC10355006
Declarations
PMC10355006
Ethical approval and consent to participate
All methods were performed in accordance with the declaration of Helsinki. We obtained Mansoura Faculty of Medicine, Institutional Research Board (MFM-IRB) approval (R.21.09.1462) before patient enrollment. All patients gave their written informed consent (or their guardians if their age was less than 18 years) during ...
PMC10355006
Consent for publication
Not applicable.
PMC10355006
Competing interests
Nil.
PMC10355006
References
PMC10355006
Subject terms
neuropathic pain, manipulationAcupuncture, motor and sensory performances, ELMT, CTS, CTS.Carpal tunnel syndrome, Carpal Tunnel Questionnaire, Tinel
ENTRAPMENT NEUROPATHY, CARPAL TUNNEL SYNDROME (CTS)
This study aimed to evaluate the clinical efficacy of an electroacupuncture-like magnetic therapy (ELMT) and conventional transcutaneous electrical nerve stimulation (TENS) in patients with carpal tunnel syndrome (CTS). A prospective randomized controlled trial in single-centre was conducted. Thirty-four CTS patients c...
PMC10656569
Methods
PMC10656569
Participants and design
CTS
The design of this study is as a prospective randomized, single-center, interventional clinical trial with two parallel assignment groups. This study has been registered on ClinicalTrials.gov, and the Identifier is NCT01277003 (14/01/2011). The potential participants were patients who visited our outpatient clinics wit...
PMC10656569
Inclusion criteria
pain, numbness, CTS
In this study, CTS was diagnosed clinically by senior physicians with at least one of the symptoms of numbness, tingling, or pain in the wrist or hand. The diagnosis was further confirmed with electrodiagnostic studies, which indicated at least one of the following criteria
PMC10656569
Exclusion criteria
fracture, diabetes mellitus, numbness, CTS, gout, peripheral neuropathy, trauma
RHEUMATOID ARTHRITIS, CHRONIC RENAL FAILURE, DIABETES MELLITUS, SYSTEMIC LUPUS ERYTHEMATOSUS, GOUT, DISORDERS, POLYNEUROPATHY, CERVICAL SPONDYLOSIS, HYPOTHYROIDISM, PERIPHERAL NEUROPATHY
The medical and surgical conditions that predispose one to peripheral neuropathy such as hypothyroidism, gout, systemic lupus erythematosus, rheumatoid arthritis, diabetes mellitus, chronic renal failure; the presence of disorders such as cervical spondylosis, polyneuropathy, that might cause numbness in the hand; trea...
PMC10656569
Baseline testing and outcome measurement
The participant would be first evaluated using the BCTQ
PMC10656569
Allocation
carpal tunnel syndromes, ELMT, CTS
CARPAL TUNNEL SYNDROME
We then randomly assigned the participants into two treatment groups, but tried to evenly distribute them to be matched with similar demographic characteristics and CTS severity. One group received conventional TENS (TENS group) and another group received ELMT with Aculife (ELMT group). Forty patients with carpal tunne...
PMC10656569
Interventions
All the assessment and the treatment were carried out in the outpatient clinics of the Department of Physical Medicine and Rehabilitation of our hospital. The intervention program would last for six weeks, one treatment session each day, 5 sessions per week. Each session consisted of one electrophysical modality treatm...
PMC10656569
Electroacupuncture-like magnetic therapy treatment
ELMT
The ELMT treatment was delivered with a magnetic therapy device (Aculife Magnetic Wave device, SMW-A01, Innohealth Technology Co., Taiwan). It is designed to deliver surface acupuncture-like stimulation, using a biphasic pulse with one high-voltage square phase in positive direction and then quickly changed in polarity...
PMC10656569
Conventional TENS treatment
A typical TENS machine was used (GEM-STIM GM3A5XT, Chi-Mao Co., Taiwan) to delivered conventional TENS treatment. Two adhesive round electrodes (2.5 cm radius) were applied to the same treatment positions, as described above. Negative electrodes were placed on the carpal ligament (covering PC-6), and positive electrode...
PMC10656569
Statistical analysis
Carpal Tunnel Questionnaire
Boston Carpal Tunnel Questionnaire (BCTQ) scores, motor and sensory performances, provocation signs, and electro-diagnostic measurements were evaluated before and after the treatment program to measure the treatment effectiveness. Statistical Package for the Social Sciences software (IBM Corp., Armonk, NY, USA) was use...
PMC10656569
Ethical approval
This research was reviewed and approved by the institutional review board of China Medical University Hospital (Protocol No. DMR99-IRB-223), and has been registered on ClinicalTrials.gov (Identifier: NCT01277003, 14/01/2011). This study was performed in accordance with the standards of ethics outlined in the Declaratio...
PMC10656569
Results
At the end of the study, 17 participants (13 females, 4 males) in the TENS group and 17 (15 females, 2 males) in the ELMT group completed the treatment programs (Fig. 
PMC10656569
Motor and sensory performance
There was no significant difference between two groups in grip strength, pinch strength and two-point discrimination
PMC10656569
Acknowledgements
The authors acknowledge the financial support by the China Medical University Hospital (DMR-106-135) and the Innohealth Technology Co. (0994266G). We are also grateful to all participants for their cooperation and contribution to complete this study.
PMC10656569
Author contributions
S.-F.L.: Conceptualization, methodology, investigation, funding acquisition, and writing—review & editing, project administration; L.-W.C.: Conceptualization, methodology, resources, funding acquisition, and writing—review and editing. H.C.: Investigation, formal analysis, writing—original draft, and visualization; H.C...
PMC10656569
Funding
The Project is funded by China Medical University Hospital (DMR-106-135) and the Inno-health Technology Co., Ltd. (0994266G).
PMC10656569
Data availability
The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
PMC10656569