title stringlengths 1 1.19k | keywords stringlengths 0 668 | concept stringlengths 0 909 | paragraph stringlengths 0 61.8k | PMID stringlengths 10 11 |
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Keywords | PMC10413762 | |||
Introduction | eclampsia | PREECLAMPSIA, ECLAMPSIA, GESTATIONAL HYPERTENSION, HYPERTENSION IN PREGNANCY | Hypertension in pregnancy, including gestational hypertension, preeclampsia, and eclampsia, is a pervasive global health issue affecting approximately 10% of pregnant women worldwide [ | PMC10413762 |
Data and methods | PMC10413762 | |||
General data | MILD PREECLAMPSIA, HYPERTENSION IN PREGNANCY, SEVERE PREECLAMPSIA, GESTATIONAL HYPERTENSION | The 531 gestational hypertension patients admitted to our hospital between October 2019 and January 2023 were randomly divided into a modeling group (427 cases) and a validation group (104 cases). Within the modeling group, patients were further categorized into a critical group (59 cases) and a non-critical group (368... | PMC10413762 | |
Data collection | HYPERTENSION IN PREGNANCY | Clinical data of patients with hypertension in pregnancy were collected and recorded, including age (≤ 30 years, > 30 years), BMI (≤ 28 kg/m | PMC10413762 | |
Statistical processing | SPSS 25.0 statistical software was used for analysis. The measurement data conformed to normal distribution by ( | PMC10413762 | ||
Results | PMC10413762 | |||
Comparison of clinical data between the modeling group and the validation group | HYPERTENSION, GESTATIONAL NEPHROPATHY, ANEMIA DURING PREGNANCY, GESTATIONAL DIABETES | There was no statistically significant difference between the modeling group and the validation group in terms of age, BMI, education, living environment, family history of hypertension, gestational week, number of pregnancies, number of deliveries, anemia during pregnancy, gestational nephropathy, gestational diabetes... | PMC10413762 | |
Comparison of clinical data between critical and non-critical patients in the modeling group | GESTATIONAL NEPHROPATHY, GESTATIONAL DIABETES | There was no statistically significant difference between the non-critical group and the critical group in terms of BMI, living environment, gestational week, number of pregnancies, number of deliveries, gestational nephropathy, gestational diabetes, platelet count, and red blood cell count (
Comparison of clinical dat... | PMC10413762 | |
Multiple logistic regression analysis of the development of critical conditions in patients with hypertension in pregnancy | hypertension | REGRESSION, HYPERTENSION IN PREGNANCY, HYPERTENSION, ANEMIA DURING PREGNANCY | The occurrence of critical conditions in patients with hypertension during pregnancy was used as the dependent variable, with a value of 1 indicating presence and 0 indicating absence. Age (1 = > 30 years, 0 = ≤ 30 years), education (1 = junior high school and below, 0 = high school and above), family history of hypert... | PMC10413762 |
Construction of a risk prediction nomogram model for the multiple Logistic regression analysis on the development of critical illness in patients with hypertension in pregnancy | hypertension | REGRESSION, HYPERTENSION IN PREGNANCY, HYPERTENSION, ANEMIA DURING PREGNANCY | Based on the results of the multiple logistic regression analysis described above, a nomogram model was developed to predict the risk of critical conditions in patients with hypertension during pregnancy. The model assigns 14.9 points for age > 30 years old, 8.6 points for junior high school education or below, 12.5 po... | PMC10413762 |
Internal validation of the nomogram model for predicting the risk of critical conditions in patients with hypertension in pregnancy | hypertensive | For the modeling group, ROC curve was plotted to validate discrimination of the nomogram prediction model. The results showed that the AUC of the nomogram for predicting the risk of critical conditions was 0.926 (95% CI = 0.887–0.964), with good discrimination, as shown in Fig.
Receiver operating characteristic and co... | PMC10413762 | |
External validation of the nomogram model for predicting the risk of critical conditions in patients with hypertension in pregnancy | hypertensive | In the validation group, the AUC of the nomogram for predicting the risk of critical condition was 0.942 (95% CI = 0.872–0.998), with good discrimination, as shown in Fig.
Receiver operating characteristic and correction curve of nomogram model for predicting the severity of hypertensive patients during pregnancy | PMC10413762 | |
Importance score of risk factors for critical situations in patients with gestational hypertension | hypertensive | HYPERTENSION, ANEMIA DURING PREGNANCY | Based on the Gini coefficient, which measured the importance score of each variable, the results indicated that age was the most influential factor impacting critical conditions in hypertensive patients during pregnancy. Following age, the variables in descending order of importance were red blood cell count, anemia du... | PMC10413762 |
Acknowledgements | Not applicable. | PMC10413762 | ||
Authors’ contributions | Pingping Zhang: Data Collection, Manuscript writing. Xiwen Zhong: Project development, Data collection, Data analysis,Manuscript editing. | PMC10413762 | ||
Funding | None. | PMC10413762 | ||
Data Availability | The [DATA TYPE] data used to support the findings of this study are included within the article. | PMC10413762 | ||
Declarations | PMC10413762 | |||
Research involving human participants and/or animal | RECRUITMENT | The study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of Wenzhou Central Hospital, Zhejiang, China (Approval number:WZZXLL20230103). All participants provided written consent before recruitment in this study. | PMC10413762 | |
Consent for publication | Not applicable. | PMC10413762 | ||
Competing interests | The authors declare no competing interests. | PMC10413762 | ||
References | PMC10413762 | |||
Background | Neuropathic Pain, neuropathic pain, pain | ADVERSE EFFECTS | Academic Editor: Alessandro Vittori A qualitative evaluation study of the prematurely terminated PrEgabalin Lidocaine Capsaicin Neuropathic Pain (PELICAN) study was performed. The PELICAN study aimed to examine pain management for localized neuropathic pain (LNP), as epidemiological figures have shown a high percentage... | PMC10121349 |
Objective | pain | RECRUITMENT | Achieving better study patient recruitment through qualitative research. To investigate and determine the causes of the observed recruitment problems in the PELICAN study, pain centers involved in the study as well as nonrecruiting pain centers were included. Furthermore, it aimed to highlight the positive and negativ... | PMC10121349 |
Methods | pain | RECRUITMENT | A qualitative study, using a mixed methods approach, was performed. Multiple pain centers in Belgium completed an online survey, after which a structured interview was conducted to elaborate the responses in more detail. The broad topics of these meetings were feedback about the study, reviewing survey answers, and ac... | PMC10121349 |
Results | nonpain, pain | RECRUITMENT | Different factors contributed to the low recruitment rate in the PELICAN study, such as limited and late referral from the general practitioners to the Belgian pain centers, insufficient internal referrals from nonpain specialists, lack of specific expertise on LNP in some centers, scarcity of staff, limited reimburse... | PMC10121349 |
Conclusion | RECRUITMENT | The findings of the qualitative study demonstrate the need for further, more varied LNP research in Belgium, not limited to pharmacological studies. It also sheds important light on the recruitment obstacles that may be faced during these studies. Future studies could support this research by offering better proposals... | PMC10121349 | |
1. Introduction to the PrEgabalin Lidocaine Capsaicin Neuropathic Pain (PELICAN) Pragmatic Trial | chronic pain, overdose | RECRUITMENT, ADVERSE EVENTS, RECRUITMENT, ADVERSE EFFECTS, SYNDROMES, CHRONIC PAIN | Moderate to severe chronic pain occurs in 19% of European adults, significantly affecting the quality of their social and professional lives [The PELICAN study was a randomized, multicenter, comparative pragmatic trial that aimed to examine topical versus systemic treatment in adult patients with LNP syndromes. Systemi... | PMC10121349 |
2. Methodology of the Qualitative Research Trial (Mixed Methods Approach) | pain | RECRUITMENT | A qualitative research project was conducted after the comparative trial was terminated. An explanatory sequential research design was hereby applied, in which quantitative data collection and analyses occurred first, followed by qualitative data collection and analyses [An easy-to-fill online questionnaire was created... | PMC10121349 |
3. Findings | neuropathic pain, anxiety, Neuropathic pain, pain, PHN | PHN, RECRUITMENT, INFILTRATION, RECRUITMENT, SYNDROMES | The qualitative study revealed several different reasons for the low recruitment rate. One of the reasons was the somewhat limited clinical trial experience in approximately half of the participating pain centers. Responses varied that centers performed one to eight clinical trials every 5 years. Furthermore, a signifi... | PMC10121349 |
4. Discussion | neuropathic pain, illness, Pain, anxiety, toxicity, pain, PHN, head and neck cancer, nonpain, peripheral neuropathic pain, chronic pain, IASP | PHN, ADVERSE EVENTS, RECRUITMENT, HEAD AND NECK CANCER, CHRONIC PAIN, DRUG-DRUG INTERACTION | A majority of patients with neuropathic pain suffer from LNP. Based on the International Association for the Study of Pain (IASP), LNP is described as a type of peripheral neuropathic pain characterized by consistent and circumscribed area(s) of maximum pain associated with abnormal sensitivity of the skin and/or spont... | PMC10121349 |
5. Conclusion | neuropathies, neuropathic pain, subacute pain, pain | CHRONIC PAIN SYNDROMES, RECRUITMENT, NEUROPATHIES, SYNDROMES, CHRONIC PAIN | The participating pain centers considered low enrollment in the PELICAN study, mainly due to insufficient (timely) referral from primary healthcare providers and other specialties, to be the main issue leading to the study's premature cessation. Additionally, poor recruitment was also attributed to the too strict inclu... | PMC10121349 |
Acknowledgments | Special thanks are due to the members of the Trial Steering Committee for their continued support, practical suggestions, and advice during the difficult execution of the study. Your input was already highly appreciated. The authors would like to express their special gratitude and thanks to the external experts, Prof.... | PMC10121349 | ||
Data Availability | The data from the pragmatic study are available through the website from the funder (KCE Clinical Trials). The link to the website and the research synopsis report is also mentioned in the manuscript: | PMC10121349 | ||
Disclosure | The PELICAN Investigators Team consists of Jan Pieter Haems, Mirella Dingens, Frans Van De Perck, Michel Dangoisse, Olivier De Coster, Nathalie Mathieu, Milica Matic, and Bart Morlion. | PMC10121349 | ||
Conflicts of Interest | neuropathic pain, pain | SYNDROMES, RECRUITMENT | The authors declare that they have no conflicts of interest.Overview of the study design of the PELICAN pragmatic trial as originally conceived.Different flowcharts that were evaluated in the survey as possible first-choice treatment approaches for localized neuropathic pain conditions within Belgian multidisciplinary ... | PMC10121349 |
Background | obesity, obese, periodontitis, inflammation, MetS, metabolic syndrome | OBESITY, OBESE, STILL, PERIODONTITIS, INFLAMMATION, METABOLIC SYNDROME | Epidemiological studies support an association between obesity, metabolic syndrome (MetS), and periodontitis. Still, understanding of the effects of low-grade inflammation in obese subjects on periodontitis and influence of MetS remains incomplete. The aims of this cross-sectional study were to explore the association ... | PMC10315020 |
Methods | The study sample comprised 52 adults with a body mass index (BMI) of ≥ 30 kg/m | PMC10315020 | ||
Results | obesity, periodontitis, MetS | OBESITY, PERIODONTITIS | In the present sample 79% of the subjects were diagnosed with periodontitis. The prevalence of stage III/IV periodontitis was 42.9% in the non-MetS group vs. 36.8% in the MetS group (p = 0.200). In the non-MetS group 29.8% of the sites displayed BoP vs. 23.5% in the MetS group (p = 0.048). For stage III/IV periodontiti... | PMC10315020 |
Conclusion | obesity, periodontitis, MetS | OBESITY, PERIODONTITIS, OBESE | In the present sample of obese subjects, periodontitis occurred independently of MetS. Reaching a certain BMI level, suggested association between MetS and periodontitis might be non-significant due to the dominating impact of obesity related variables undermining the effect of other systemic factors. | PMC10315020 |
Trial registration | Obesity | OBESITY, ORAL DISEASE | The principal clinical trial, entitled “Obesity and Oral Diseases”, was prospectively registered in ClinicalTrials.gov with registration NCT04602572 (20.10.2020). | PMC10315020 |
Keywords | Open access funding provided by University of Bergen. | PMC10315020 | ||
Background | obesity, obese, TNF-α, inflammation, periodontitis, MetS, tooth, hypertension, TG | OBESITY, METABOLIC SYNDROME, INFLAMMATORY DISEASE, OBESE, FUNCTIONAL DISTURBANCE, INFLAMMATION, DISEASE, PERIODONTITIS, PERIODONTITIS, OVERWEIGHT AND OBESITY, HYPERTENSION, DISEASES, INCREASED INSULIN | Overweight and obesity increasing globally are considered major challenges to human health services [Metabolic syndrome (MetS) represents an assembly of functional disturbances including obesity, increased waist circumference, increased insulin levels/blood glucose, hypertension and/or low high-density lipoprotein (HDL... | PMC10315020 |
Methods | Obesity | OBESITY, ORAL DISEASE | The study protocol and informed consent following the Helsinki Declaration of 1975 (version 2008) was approved by the Norwegian Regional Ethics Committee (Reference 152,810–22/02/2021/REK Vest). The principal clinical trial, entitled “Obesity and Oral Diseases”, was prospectively registered in ClinicalTrials.gov with r... | PMC10315020 |
Study design and setting | Obesity | OBESITY, PATHOLOGY | The present cross-sectional study enrolled subjects from the Obesity Centre, Section of Endocrinology, Haukeland University Hospital (HUH), Bergen, Norway, January 2021 through September 2021. Medical data and fasting blood samples were collected at enrolment. A clinical periodontal examination was performed at the Dep... | PMC10315020 |
Pre-study calibration and sample size calculation | PD, tooth | One examiner (AT) unaware of group assignment performed all clinical examinations. Prior to initiation of the study, two separate calibration exercises were performed: 1: Examiner AT was calibrated with an experienced periodontist (KNL) and 2: Examiner AT performed an exercise to assess intra-examiner reproducibility f... | PMC10315020 | |
Study subjects | obesity, mental illness, periodontitis, ’s syndrome, psychosis, bulimia nervosa, depression, endocrine disease | OBESITY, PERIODONTITIS, HYPERCORTISOLISM, HEAD AND NECK CANCER, HYPOTHYROIDISM, ENDOCRINE DISEASE | The study included subjects with an initial body mass index (BMI) ≥ 30 kg/mStudy exclusion criteria included leukaemia/neutropenia, HIV/AIDS, pregnancy, use of immunosuppressive drugs, mental illness (active psychosis, severe depression), Sjögren’s syndrome, obesity caused by endocrine disease (e.g., hypercortisolism, ... | PMC10315020 |
Questionnaire | Upon arrival for the clinical examination, study subjects completed a multiple-choice questionnaire including demographic items, general health, medication, smoking, oral health/hygiene, and dietary habits. Questions were repeated orally if there were missing answers resulting in a 100% response rate. The questionnaire... | PMC10315020 | ||
Periodontal examination | Bleeding, PD, bleeding, tooth | BLEEDING, BLEEDING | The following clinical parameters were recorded: PD (distance in mm from the gingival margin to the base of the periodontal pocket); and CAL (distance in mm from the cemento-enamel junction or the margin of a dental restoration to the base of the pocket) using a periodontal probe (PCPUNC 15, Hu-Friedy, Chicago, IL, USA... | PMC10315020 |
Periodontal diagnosis | DISEASES, PERIODONTITIS | Periodontitis was diagnosed and classified using the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions [ | PMC10315020 | |
Statistical analysis | PD, tooth | REGRESSION | Mean values and standard deviations were used to describe continuous variables. For categorical variables frequencies and percentages were used. Quantitative variables such as PD and CAL were sectioned into three distinct groups: 0–3 mm [For continuous variables at patient level, two-group t-test was used to test stati... | PMC10315020 |
Discussion | PMC10315020 | |||
Summary and comparison with other studies | periodontitis, MetS | OBESE, PERIODONTITIS, DISEASE, REGRESSION, HIV PERIODONTITIS | In a sample of obese subjects with a mean BMI of 41.5 kg/mWe hypothesized that MetS would promote a more severe periodontal conditions in obese subjects. However, the prevalence of periodontitis was similar (78.6% in non-MetS vs. 78.9% in MetS), the non-MetS group exhibiting a slightly higher prevalence severe periodon... | PMC10315020 |
Methodological challenges and strengths | obesity, PD | OBESITY, DISEASE, OBESE, PLAQUE | The unbalanced distribution of subjects within the two groups, with a lower number of subjects included in the non-MetS group, might undermine the statistical power of the study. In the present study, staging and grading were primarily based on clinical measures such as CAL, PD, furcation involvement, and bitewing radi... | PMC10315020 |
Acknowledgements | This study was funded by a grant from Meltzer. Sincere thanks are expressed to Professor Ulf M.E. Wikesjö for reviewing the manuscript. | PMC10315020 | ||
Authors’ contributions | All authors made substantial contributions to conception and design of the study. AT, AN and PM collected the data and SAL analyzed the data. AT, AN, KNL, SAL, PM, DFB, and KKR have been involved in data interpretation, drafting the manuscript, and revising it critically and have given final approval of publishing. | PMC10315020 | ||
Funding | The study was funded by the authors and their institutions.Open access funding provided by University of Bergen. | PMC10315020 | ||
Data Availability | The datasets used and analysed during the current study and coding are available from the corresponding author on reasonable request. | PMC10315020 | ||
Declarations | PMC10315020 | |||
Ethics approval, consent to participate, and guidelines | The study protocol and informed consent, following the Helsinki Declaration of 1975, version 2008, have been approved by the Norwegian Regional Ethics Committee (Reference 152810–22/02/2021/REK Vest). The study subjects were informed of the nature, scope, and consequences of participating in the study before signing th... | PMC10315020 | ||
Consent to publish | Not applicable. | PMC10315020 | ||
Competing interests | The authors declare no competing interests. | PMC10315020 | ||
Abbreviations | mass indexMetabolic | Body mass indexMetabolic syndromeHaukeland University HospitalProbing depthBleeding on probingClinical attachment levelHigh-density lipoproteinHigh triglycerideC-reactive proteinIntraclass correlation coefficientsWaist circumstanceBlood pressure | PMC10315020 | |
References | PMC10315020 | |||
Introduction | cognitive impairment, MCI, dementia, declines in cognition compared, Alzheimer’s disease, depression, cognitive decline, AD | Corresponding Author: Y.-I. ShinClinical and Translational Impact Statement—The HB-CCT may be a positive tool for cognitive functioning improvement in community-dwelling adults with MCI.Objective: There is a growing importance for the home-based (HB) support services, and computerized cognitive training (CCT) has been ... | PMC10712670 | |
Methods | PMC10712670 | |||
Study Design and Participants | ADVERSE EVENTS, RECRUITMENT | This single-blinded, randomized control pilot study was conducted between 22 April 2020–2 August 2021. The study was approved by the Institutional Review Board of Pusan University Yangsan Hospital (IRB no. 02-2019-018) and registered on Clinictrials.gov (NCT05275153). All participants provided written informed consent ... | PMC10712670 | |
Home-Based Computerized Cognitive Training | Neuro-World | The Neuro-World (Woorisoft Inc., Daegu, Republic of Korea) HB-CCT (Version: 1.0, Server-OS: Microsoft Windows Server 2008 Enterprise SP2 (64bit), DBMS: MySQL 5.5, WAS: IIS 7, PHP: PHP 5.6, Client-OS: over Android 6.0) was used in this study. The software trains attention, visual perception, memory, and executive functi... | PMC10712670 | |
Evaluation | finger pain, headaches | ADVERSE EVENT | The HB-CCT group underwent baseline evaluations prior to the intervention and post evaluations after the 8-week intervention. The control group underwent baseline evaluations and post-evaluations eight weeks later. The primary outcome was MoCA as an indicator of overall cognitive function We evaluated the safety of HB-... | PMC10712670 |
Usability and Adherence | To evaluate the usability and adherence of HB-CCT, we conducted observations and collected user feedback. When users encountered difficulties or issues while using HB-CCT, we identified improvement points through phone or video calls based on their feedback. Additionally, administrators monitored the usage of HB-CCT to... | PMC10712670 | ||
Statistical Analysis | Statistical analysis was performed using SPSS Statistics version 18 (SPSS Inc., Chicago, IL) and R statistical programming software package. As data from the HB-CCT and control groups followed a normal distribution with homogeneous variance, they were analyzed using parametric analysis. Paired | PMC10712670 | ||
Comparison of Baseline-Controlled Post-Evaluation Scores Between the HB-CCT and Control Groups | Depression | Abbreviations: SS (Type III Sum of Squares), DF (Degree of Freedom), MS(Mean Square), MoCA (Montreal Cognitive Assessment), VLT (Verbal Learning Test), DST(Digit Span Test), SWF (Semantic Word Fluency Test), PWF (Phonemic Word Fluency Test), GDS (Geriatric Depression Scale), Comparisons of the changes in the evaluation... | PMC10712670 | |
Comparison of Evaluation Scores at Baseline and Post (After Eight Weeks) in Each Group | Depression | Data are expressed as means ± standard deviation. Abbreviations: MoCA (Montreal Cognitive Assessment), VLT (Verbal Learning Test), DST(Digit Span Test), SWF (Semantic Word Fluency Test), PWF (Phonemic Word Fluency Test), GDS (Geriatric Depression Scale), The following are the results regarding usability and adherence. ... | PMC10712670 | |
Discussion | fatigue, cognitive impairment, dementia, MCI, depression, cognitive decline | SECONDARY | The results of this study indicated that the HB-CCT performed in community-dwelling adults with MCI improved cognitive function and reduced depression levels compared to the control group. As patients with MCI typically carry higher risks of developing dementia compared with healthy older adults, continuous efforts to ... | PMC10712670 |
Conclusion | Neuro-World, depression, MCI, HB-CCT failure | In this study, we introduced a home-based cognitive treatment method, namely the Neuro-World, for community-dwelling adults with MCI. We have empirically demonstrated the efficacy of HB-CCT through various evaluations, including language, memory, executive function, and depression. This study proved that HB-CCT is a us... | PMC10712670 | |
Appendix A | See | PMC10712670 | ||
Linear Mixed-Effect Model Results for Each Groups According Times | Abbreviations: SE(Standard Error), DF(Degrees of Freedom), | PMC10712670 | ||
Appendix B | See | PMC10712670 | ||
Linear Mixed-Effect Model Results for Speed per Item and Training Stage of HB-CCT Group | Abbreviations: num(numerator), den(denominator), DF(Degrees of Freedom), | PMC10712670 | ||
Appendix C | See | PMC10712670 | ||
Estimates of Fixed Effects b of Linear Mixed-Effect Model Results for Speed per Item of HB-CCT Group | SE | Abbreviations: SE (Standard Error), DF (Degrees of Freedom), | PMC10712670 | |
Appendix D | See | PMC10712670 | ||
References | PMC10712670 | |||
1. Introduction | obesity, overweight, overweight or obesity | OBESITY, OBESE | These authors contributed equally to this work.Many current treatment options for managing overweight and obesity consist of rather strict diet and exercise regimes that are difficult to implement as a lifelong routine. Therefore, alternative initiatives such as mindful eating and pleasure-oriented physical activity wi... | PMC10096929 |
2. Materials and Methods | PMC10096929 | |||
2.1. Trial Design | This study was an exploratory open-label, parallel-arm, randomized controlled superiority trial, where participants were allocated by block randomization to one of three intervention groups (mindful eating alone, YogaDance alone, or mindful eating and YogaDance combined; see below for more details) or the control group... | PMC10096929 | ||
2.2. Sample Size Calculation | Heydari and colleagues found a reduction in fat mass of 2.1 kg between high-intensity intermittent exercise and no exercise groups; the study also provided an SD of 1.9 kg [ | PMC10096929 | ||
2.3. Participants | Participants were recruited via social media on Facebook and Instagram as well as on the Danish websites | PMC10096929 | ||
2.4. Intervention | PMC10096929 | |||
2.4.1. Intervention Groups | The intervention period was 8 weeks. The YogaDance intervention group followed three weekly YogaDance classes (in total. 24 classes), whereas the mindful eating group attended a workshop every second week (in total four workshops). The combined mindful eating and YogaDance intervention group followed both three weekly ... | PMC10096929 | ||
2.4.2. Components of the Intervention | low lunges, boat pose and chair, eating behavior, dancer | STRETCHES | Each mindful eating workshop lasted 90 min. The program was centered around 10 eating principles (For YogaDance, the training intensity was selected to ensure participant adherence and meet the recommendations by the WHO for physical activity for adults (i.e., 150 min at moderate intensity or 75 min at high intensity p... | PMC10096929 |
2.5. Outcomes and Measurements | eating behavior | SECONDARY | The primary outcome was fat mass. The secondary outcomes were body weight, BMI, waist circumference, fat percent, fat-free mass, visceral fat, bone mineral density, blood pressure, quality of life, eating behavior, energy intake, and physical activity. For all outcomes, measurements were recorded both at baseline and a... | PMC10096929 |
2.5.1. Anthropometry | CREST | Height was only measured at the baseline. The participant was asked to remove shoes and to stand upright with the back to the wall-mounted stadiometer so that the back of the head, back, and buttock touched the stadiometer. The participant was further instructed to look straight ahead and to hold the arms relaxed, hang... | PMC10096929 | |
2.5.2. Body Composition | Dual X-ray absorptiometry was used to measure fat mass, FFM, visceral fat, and BMD on a DXA scanner (Lunar iDXA with CoreScan module, GE Healthcare, Brøndby, Denmark). The scan was performed in a fasted state in the morning. The scan lasted approximately 10 min with the participant lying on her back on an open bed whil... | PMC10096929 | ||
2.5.3. Other Measurements | Systolic and diastolic blood pressures were measured using a validated automatic blood pressure monitor (UA-787 Plus) on the arms of participants that had rested 5–10 min in a sitting position prior to measuring. Measurements (recorded to the nearest 1 mmHg) were taken twice on both arms and averaged. In order to calcu... | PMC10096929 | ||
2.5.4. Questionnaire Data: Quality of Life, Eating Behavior, and Physical Activity | fatigue | All questionnaires were electronic and distributed to the participants via e-mail. SurveyXact (Rambøll Management Consulting, Aarhus, Denmark) was used for creating the questionnaires. The first questionnaire included the WHO-QOL-100 physical and mental dimensions, which examine a wide range of parameters related to qu... | PMC10096929 | |
2.5.5. Compliance | All questionnaires were electronic and distributed to the participants via e-mail. SurveyXact Participation in YogaDance classes and mindful eating workshops was recorded by means of checklists (ticking off participants that showed up). Compliance was calculated for the participants who completed the trial. | PMC10096929 | ||
2.6. Statistical Analysis | Descriptive statistics of baseline characteristics for participants within each intervention or the control group were obtained using medians and interquartile ranges.Intention-to-treat (ITT) analyses were carried out based on all participants who were randomized. In the case of missing values, multiple imputation thro... | PMC10096929 | ||
3. Results | PMC10096929 |
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