Unnamed: 0 int64 0 1.1k | MICROBE stringlengths 2 45 | DISEASE stringlengths 2 53 | EVIDENCE stringlengths 58 610 | RELATION stringclasses 4
values | QUESTIONS stringlengths 44 112 |
|---|---|---|---|---|---|
200 | Aggregatibacter actinomycetemcomitans | periodontitis | For example, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, and Prevotella intermedia have traditionally been considered pathogenic bacteria contributing to periodontitis [5, 12, 13]. | positive | What is the relationship between Aggregatibacter actinomycetemcomitans and periodontitis? |
201 | Fusobacterium | HIV | In addition to the shared nine predominant genera in both groups, Megamonas, Blautia, Parabacteroides, Veillonella, Parasutterella and Fusobacterium were also abundant members of the fecal microbiota in patients with HIV. | relate | What is the relationship between Fusobacterium and HIV? |
202 | Faecalibacterium prausnitzii | IBD | From various IBD studies, etiologically implicated bacteria include Faecalibacterium prausnitzii exerting a positive impact, described as anti-inflammatory, while Escherichia coli and Mycobacterium avium paratuberculosis (MAP) have a negative impact as potential IBD infectious agents [5, 8?12]. | negative | What is the relationship between Faecalibacterium prausnitzii and IBD? |
203 | Enterococcus faecium | cholangitis | The causative pathogens and foci included the following: 3 episodes of Staphylococcus aureus surgical site infections, 3 episodes of Enterococcus faecium cholangitis, 2 episodes of intra-abdominal infections caused by Escherichia coli, an intra-abdominal abscess caused by E. faecium, a ventilator-associated pneumonia c... | positive | What is the relationship between Enterococcus faecium and cholangitis? |
204 | E. faecalis | alcoholic cirrhosis | Beyond the intestine, Enterococcus expansion is linked to hepatic inflammation in hepatitis B virus-related cirrhosis and E. faecalis enhances inflammation in mouse models of alcoholic cirrhosis with gastric acid suppression. | positive | What is the relationship between E. faecalis and alcoholic cirrhosis? |
205 | Granulicatella adiacens | pancreatic cancer | For example, the salivary microbiome profiles exhibited 94% sensitivity and 82% specificity in distinguishing patients with early-stage, resectable pancreatic cancer based on shifts in the microbial signature, with Neisseria elongata and Streptococcus mitis emerging as specific biomarkers, whereas Granulicatella adiace... | relate | What is the relationship between Granulicatella adiacens and pancreatic cancer? |
206 | Gemella haemolysans | tumor | The unnamed cultivable taxon, Streptococcus sp. oral taxon 058, and named cultivable bacterial species, Gemella haemolysans, Gemella morbillorum, Gemella sanguinis, Johnsonella ignava, Peptostreptococcus stomatis, Streptococcus gordonii, Streptococcus parasanguinis I, Streptococcus salivarius were highly associated to ... | relate | What is the relationship between Gemella haemolysans and tumor? |
207 | Veillonella | gingivitis | Moreover, 58 OTUs affiliated to the genera of Leptotrichia (16), Selenomonas (12), Streptococcus (7), Veillonella (6), Prevotella (6), Lautropia (2), Haemophilus (3) and the candidate division TM7 (6) were found to be associated with gingivitis. | relate | What is the relationship between Veillonella and gingivitis? |
208 | Ruminococcus | CRC | The abundance of probiotics such as Bifidobacterium, Lactobacillus, and Ruminococcus were reduced in CRC patients. | negative | What is the relationship between Ruminococcus and CRC? |
209 | Lactobacillus casei | collagen-induced arthritis (CIA) | Oral administration of Lactobacillus casei (5 ? 109 CFU ? 3 times per week) was shown to protect against RA progression in a rat model, whereby L. casei suppressed collagen-induced arthritis (CIA) and reduced paw swelling, lymphocyte infiltration and destruction of cartilage tissue [78]. | negative | What is the relationship between Lactobacillus casei and collagen-induced arthritis (CIA)? |
210 | Faecalibacterium prausnitzii | inflammatory bowel diseases | For instance, the depletion of Faecalibacterium prausnitzii was correlated with inflammatory bowel diseases (IBD), including colitis and Crohn?s disease [76]. | relate | What is the relationship between Faecalibacterium prausnitzii and inflammatory bowel diseases? |
211 | Porphyromonas gingivalis (PG) | periodontitis | It has been speculated that certain species of bacteria, mainly Porphyromonas gingivalis (PG) which may be present in the oral cavity, and are increased in patients affected by periodontitis, can induce loss of tolerance and lead to citrullination of several peptides and proteins (Wegner et al., 2010; Quirke et al., 20... | positive | What is the relationship between Porphyromonas gingivalis (PG) and periodontitis? |
212 | Prevotella copri | Coeliac disease | Here, we found Prevotella and species related to Prevotella copri were higher in our non-secretor children and the children of non-secretor mothers, and these bacteria have also been reported to be present at higher levels in untreated Coeliac disease [46] and new onset rhematoid arthritis patients [47] but appear to b... | positive | What is the relationship between Prevotella copri and Coeliac disease? |
213 | Prevotella stercorea | carcinoma in adenoma | Prevotella copri and Prevotella stercorea were related to rheumatoid arthritis and carcinoma in adenoma, respectively (Scher et?al., 2013; Moreno, 2015; Kasai et?al., 2016). | relate | What is the relationship between Prevotella stercorea and carcinoma in adenoma? |
214 | MSS | IBD | This hypothesis is strengthened by the current finding that MSS but not MBS is highly proinflammatory in human peripheral blood mononuclear cells; and that a strong IgG response to MSS, not MBS, is seen in IBD patients compared to controls. | positive | What is the relationship between MSS and IBD? |
215 | Clostridium | IBS-SSS | In HCs, Clostridium XIVb and Clostridium IV showed indirect associations with IBS-SSS through connectivity of cortical regions (M1 and S1). | relate | What is the relationship between Clostridium and IBS-SSS? |
216 | Fusobacterium | liver cirrhosis | Intestinal dysbiosis has already been described in patients with liver cirrhosis, with an increase in Veillonella, Streptococcus, Prevotella, Lactobacillus and Fusobacterium, among others. | positive | What is the relationship between Fusobacterium and liver cirrhosis? |
217 | Propionibacterium acnes | prostate cancer | Other studies also showed a positive association between Propionibacterium acnes and the development of prostate cancer[18]. | positive | What is the relationship between Propionibacterium acnes and prostate cancer? |
218 | Citrobacter rodentium | cancer | Through epithelial injury and inflammation, chronic infections (viruses, Helicobacter pylori and other Helicobacter spp., Bacteroides fragilis, Bacteroides vulgatus, Escherichia coli, Citrobacter rodentium, Citrobacter freundii, and protozoa) are linked to carcinogenesis with approximately 18% of the worldwide cancer b... | relate | What is the relationship between Citrobacter rodentium and cancer? |
219 | Escherichia coli | intra-abdominal infections | Interestingly, Escherichia coli and Enterococcus faecium could be inferred, on the basis of relationship patterns, to be harmful, in line with previous studies, which concluded that they may cause or underlie bacteraemia and intra-abdominal infections. | positive | What is the relationship between Escherichia coli and intra-abdominal infections? |
220 | Lactobacillus acidophilus | colorectal cancer | In colorectal cancer patients, treatment with Lactobacillus acidophilus, Bifidobacterium longum, and Enterococcus faecalis decreased the abundance of pathogenic Fusobacterium, the prevalence of which is associated with both IBD and colorectal cancer. | negative | What is the relationship between Lactobacillus acidophilus and colorectal cancer? |
221 | Lactobacillus bulgaricus | colitis | Previous studies have shown that Lactobacillus bulgaricus can reduce colitis, and Lactobacillus rhamnosus can effectively maintain UC remission[16]. | negative | What is the relationship between Lactobacillus bulgaricus and colitis? |
222 | Faecalibacterium prausnitzii | Crohn?s disease | Studies have demonstrated that Faecalibacterium prausnitzii, an intestinal bacterium belonging to the Clostridium cluster, was reduced in abundance in Crohn?s disease,56 and Clostridium butyricum, as a probiotic, induces interleukin-10 production in macrophages in inflamed mucosa and prevents acute experimental colitis... | negative | What is the relationship between Faecalibacterium prausnitzii and Crohn?s disease? |
223 | Helicobacter pylori | colitis-like conditions | Bacteria such as Citrobacter rodentium, Helicobacter pylori, Mycobacterium avium, and Salmonella enterica serovar Typhimurium are commonly used in animal models to trigger colitis-like conditions (Jiminez et al., 2015). | positive | What is the relationship between Helicobacter pylori and colitis-like conditions? |
224 | Desulfovibrio | adenomas | Other studies have identified Acidovorax, Bilophila, Cloacibacterium, Desulfovibrio, Helicobacter, Lactobacillus, Lactococcus, Mogibacterium, and Pseudomonas to be enriched in those with adenomas (25?27). | positive | What is the relationship between Desulfovibrio and adenomas? |
225 | Porphyromonas gingivalis | atherosclerotic plaque lesions | In fact, infection of ApoE null hyperlipidemic mice with four established periodontal pathogens?Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Fusobacterium nucleatum, led to elevations of serum inflammatory markers and progression of atherosclerotic plaque lesions [16]. | positive | What is the relationship between Porphyromonas gingivalis and atherosclerotic plaque lesions? |
226 | haemorrhagic colitis | haemolytic uraemic syndrome | Enterohaemorrhagic Escherichia coli (EHEC) has been reported to be a cause for many illnesses ranging from mild diarrhoea to more severe diseases like haemolytic uraemic syndrome or haemorrhagic colitis (Tarr et?al., 2005). | positive | What is the relationship between haemorrhagic colitis and haemolytic uraemic syndrome? |
227 | Mycobacterium paratuberculosis | inflammatory bowel diseases | In humans, Fusobacterium spp., Fusobacterium varium, Fusobacterium nucleatum, and Mycobacterium paratuberculosis have been implicated in the development of inflammatory bowel diseases (such as ulcerative colitis (UC) [29, 30], and Crohn?s disease (CD) [1, 34, 39]) and colorectal cancer [4, 19, 42]; diseases not commonl... | relate | What is the relationship between Mycobacterium paratuberculosis and inflammatory bowel diseases? |
228 | Campylobacter jejuni | diarrhea | Other diarrhea-causing pathogens (e.g., Vibrio cholerae and Campylobacter jejuni) have also been studied for their fecal volatilome, however not as heavily as C. difficile. | positive | What is the relationship between Campylobacter jejuni and diarrhea? |
229 | Tannerella forsythia | periodontitis | We noticed an increase in the ecotype 2 of four specific species (Prevotella nigrescens, Fusobacterium nucleatum vincentii, Tannerella forsythia, and Treponema denticola) known to be involved in periodontitis and a decrease of two species (Eikenella corrodens and Streptococcus sp.) | relate | What is the relationship between Tannerella forsythia and periodontitis? |
230 | Bifidobacteria | HCC | The sequencing of 16S bacterial RNA showed in the stool of HCC patients increased abundance of Bacteroides, Ruminococcus, Enterococcus, Phascolarctobacterium, and Oscillospira and decreased abundance of Bifidobacteria and Blautia as compared with liver cirrhosis without HCC. | negative | What is the relationship between Bifidobacteria and HCC? |
231 | E. coli Nissle | inflammatory bowel disease | In addition, Bifidobacterium animalis has been shown to protect against infections in infants [144] and E. coli Nissle, in addition to being an effective treatment for Crohn?s disease and inflammatory bowel disease [145], has been shown to reduce enteric counts of multidrug-resistant E. coli [146]. | positive | What is the relationship between E. coli Nissle and inflammatory bowel disease? |
232 | Lactobacillus curvatus | obesity | Oral application of a diet supplemented with two Lactobacillus strains (Lactobacillus curvatus, L. plantarum) to obese mice reduced obesity and improved inflammatory markers in adipose tissue [106] while the administration of L. plantarum alone attenuated body weight gain and dyslipidemia in high-fat diet-fed mice [107... | negative | What is the relationship between Lactobacillus curvatus and obesity? |
233 | Prevotella copri | rheumatoid arthritis | For instance, highly active amylolytic bacteria, such as Bacteroides vulgatus and Streptococcus bovis, and species whose populations have been shown to increase in response to diets rich in RS, such as Prevotella copri and Ruminococcus gnavus, are recognized to be associated with colorectal neoplasia (30), new onset rh... | relate | What is the relationship between Prevotella copri and rheumatoid arthritis? |
234 | Enterococcus faecalis | ASD | Furthermore, when the taxa abudance between ASD and DD children were compared, two taxa were elevated in children with ASD, Brucella (FDR?=?0.05) and Enterococcus faecalis OG1RF (FDR?=?0.05), while one taxa (Flavobacterium sp. | positive | What is the relationship between Enterococcus faecalis and ASD? |
235 | Clostridium difficile | irritable bowel syndrome | Clostridium XI are short-chain fatty acid (SCFA)-producing bacteria, including Clostridium difficile, Clostridium litorale, and Clostridium lituseburense, which have been reported to be increased in irritable bowel syndrome patients [29]. | positive | What is the relationship between Clostridium difficile and irritable bowel syndrome? |
236 | Streptococcus | heart valve infections | The most common biofilm-forming bacteria include Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus viridans, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa [98,99,100,101,102,103], S. aureus and S. epidermidis are most commonly found on cardi... | relate | What is the relationship between Streptococcus and heart valve infections? |
237 | Helicobacter pylori | atherosclerosis | Specifically, a number of infectious agents have been suggested to promote atherosclerosis, e.g., Chlamydia pneumoniae, Helicobacter pylori, Hepatitis C virus, Pseudomonas aeruginosa, and Cytomegalovirus and oral bacteria such as Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Prevotella intermedia... | relate | What is the relationship between Helicobacter pylori and atherosclerosis? |
238 | Escherichia | colorectal cancer | Bacteroides, Escherichia, Acinetobacter, Fusobacterium and low fecal butyrate concentration have been proposed as potential biomarkers of colorectal cancer risk (Kostic et al., 2012; Ou et al., 2013; O?Keefe, 2016), while depletion of Faecalibacterium prausnitzii, impaired butyrate metabolism and an enrichment of Enter... | positive | What is the relationship between Escherichia and colorectal cancer? |
239 | Enterobacter cloacae B29 | obesity | Using a monoassociated gnotobiotic model, our previous data support a crucial role for one endotoxin-producing strain, Enterobacter cloacae B29, in driving aggressive obesity (23). | positive | What is the relationship between Enterobacter cloacae B29 and obesity? |
240 | Clostridium | acute appendicitis | Clostridium, Streptococcus, Chryseobacterium, Haemophilus, and Comamonas are involved in GI disorders, maternal inflammation, maternofetal immune activation, neonatal sepsis, bacteremia or meningitis, acute appendicitis, and childhood vaccination [38], [39], [40], [41], [42]. | relate | What is the relationship between Clostridium and acute appendicitis? |
241 | Lactobacillus casei | colitis | In similar studies, engineered bacteria, such as Lactobacillus casei, Lactococcus plantarum, and Streptococcus gordonii, have been used to deliver various molecules to treat colitis in animal models of IBD. | negative | What is the relationship between Lactobacillus casei and colitis? |
242 | Porphyromonas gingivalis | chronic inflammatory oral disease | The periodontitis (PD)-associated bacteria are widely studied and Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola are the species most frequently associated with this chronic inflammatory oral disease [48, 49]. | positive | What is the relationship between Porphyromonas gingivalis and chronic inflammatory oral disease? |
243 | Enterococcaceae | CRC | Simultaneously, various opportunistic pathogens, able to induce inflammatory or metabolic disorders, including Campylobacter, Enterococcaceae, Erysipelotrichaceae, and Fusobacterium are increased in CRC patients [49]. | positive | What is the relationship between Enterococcaceae and CRC? |
244 | Escherichia coli | pneumonia | [26] have investigated the intestinal flora in 30 children with recurrent pneumonia and have found that the number of Bifidobacteria decreases and the number of Escherichia coli increases in children with recurrent pneumonia compared with healthy children, thus stimulating the imbalance of intestinal flora in children ... | positive | What is the relationship between Escherichia coli and pneumonia? |
245 | Enterococcus | ADHD | We also found that the proportion of Enterococcus was significantly increased in the ADHD group, and Enterococcus has been reported to be closely related to neurotransmitter release. | positive | What is the relationship between Enterococcus and ADHD? |
246 | Lactobacillus gasseri | endothelial dysfunction | [61] demonstrated that chronic oral administration of the probiotic Lactobacillus fermentum or Lactobacillus coryniformis plus Lactobacillus gasseri restored gut eubiosis and improved endothelial dysfunction as a result of a reduced vascular proinflammatory and prooxidative status. | negative | What is the relationship between Lactobacillus gasseri and endothelial dysfunction? |
247 | Escherichia | endotoxaemia | The overgrowth of Escherichia/Shigella could possible impair the intestinal permeability resulting in worsening disease severity and complications such as endotoxaemia (Quigley et al., 2013). | positive | What is the relationship between Escherichia and endotoxaemia? |
248 | Veillonella | pulmonary diseases | Indeed, mass-DNA sequencing revealed that, besides the well-known lung pathogens, a core microbiota including four persistent anaerobes genera (Veillonella, Streptococcus, Actinomyces and Prevotella) exists and is common to pulmonary diseases (Cheung et al.2013). | relate | What is the relationship between Veillonella and pulmonary diseases? |
249 | Helicobacter pylori | gastric cancers | Human papilloma virus (HPV) causes cervical cancers (Hausen, 1996) whereas Helicobacter pylori induce gastric cancers and Mucosa-associated lymphoid tissue (MALT) lymphoma (Cover and Blaser, 2009). | positive | What is the relationship between Helicobacter pylori and gastric cancers? |
250 | Clostridium | obese | Most importantly probiotic intervention greatly modified the composition of intestinal microbiota (increased the load of Bifidobacterium, Lactobacillus, Proteobacteria, Bacteroidetes, and Peptococcaceae members and reduced the amount of Firmicutes, Clostridium, and Actinobacteria), which accelerates the weight loss in ... | negative | What is the relationship between Clostridium and obese? |
251 | Streptococcus | opportunistic infections | However, there are also exceptions: for instance, some species of Enterococcus or Streptococcus can cause opportunistic infections in humans, whereby the intrinsic resistance of LAB to many antibiotics is an additional risk factor50,51. | positive | What is the relationship between Streptococcus and opportunistic infections? |
252 | Campylobacter jejuni | diarrheal disease | Many of the diarrheal case-associated bacterial taxa identified by Pop and colleagues [2] were bacteria known to be capable of causing diarrheal disease, and previously found in this cohort with conventional diagnostic tests [8], such as Escherichia/Shigella and Campylobacter jejuni. | positive | What is the relationship between Campylobacter jejuni and diarrheal disease? |
253 | Moraxella catarrhalis | COPD | Haemophilus influenzae, Streptococcus pneumoniae, Pseudomonas aeruginosa and Moraxella catarrhalis are frequently cultured from sputa of COPD patients during exacerbations. | relate | What is the relationship between Moraxella catarrhalis and COPD? |
254 | Enterococcus | colon cancer | Interestingly, Enterococcus has been related to several cancers, such as colon cancer, and lung cancer. | relate | What is the relationship between Enterococcus and colon cancer? |
255 | Streptococcus parasanguinis I | tumor | The unnamed cultivable taxon, Streptococcus sp. oral taxon 058, and named cultivable bacterial species, Gemella haemolysans, Gemella morbillorum, Gemella sanguinis, Johnsonella ignava, Peptostreptococcus stomatis, Streptococcus gordonii, Streptococcus parasanguinis I, Streptococcus salivarius were highly associated to ... | relate | What is the relationship between Streptococcus parasanguinis I and tumor? |
256 | Fusobacterium | adenocarcinomas | Its major pro-oncogenic activities are due to the virulence factor Fusobacterium adhesin A (FadA), which is expressed on the bacterial surface, and whose corresponding gene fadA is strongly upregulated in colon tissue samples from patients with adenomas and adenocarcinomas as compared with healthy subjects. | positive | What is the relationship between Fusobacterium and adenocarcinomas? |
257 | Desulfovibrio | ulcerative colitis (UC) | Helicobacter, Escherichia/Shigella and Desulfovibrio are often associated with the pathogenesis of inflammatory bowel disease (IBD) and ulcerative colitis (UC), both of which have deleterious effects on the immune system and enhance intestinal inflammation. | positive | What is the relationship between Desulfovibrio and ulcerative colitis (UC)? |
258 | Clostridium leptum | LAD calcification | Furthermore, the Clostridium leptum group correlated with LAD stenosis (0.260, p-value = 0.035) and LAD calcification (0.351, p-value = 0.005). | relate | What is the relationship between Clostridium leptum and LAD calcification? |
259 | Parabacteroides distasonis | IBD | Generally, while the overall abundance of the order Bacteroidales is increased in IBD, in certain circumstances particular species may be reduced; Parabacteroides distasonis is significantly decreased in inflamed IBD mucosa (Zitomersky et al., 2013). | negative | What is the relationship between Parabacteroides distasonis and IBD? |
260 | Porphyromonas gingivalis | chronic disease | After establishing a subgingival biofilm, oral pathobionts, including Porphyromonas gingivalis, induce periodontitis as a chronic disease, which is attributable to host-pathobiont interactions and deleterious host immune responses in periodontal tissues. | positive | What is the relationship between Porphyromonas gingivalis and chronic disease? |
261 | Veillonella | CD | Veillonella was enriched in our CD patients with upper gastrointestinal involvement. | relate | What is the relationship between Veillonella and CD? |
262 | Eimeria maxima | NE | The main causative pathogen of NE is a spore-forming, anaerobic, and gram-positive bacterium Clostridium perfringens and NE is often associated with the predisposing factor of Eimeria maxima and/or E. acervulina infection. | relate | What is the relationship between Eimeria maxima and NE? |
263 | Faecalibacterium prausnitzii | Crohn?s disease | (21) identified Faecalibacterium prausnitzii, which is greatly reduced in Crohn?s disease patients, as an anti-inflammatory commensal bacterium in the gut by showing that the supernatant of F. prausnitzii inhibits NF-?B activation in a human IEC line and suppresses the production of pro-inflammatory cytokines both in v... | negative | What is the relationship between Faecalibacterium prausnitzii and Crohn?s disease? |
264 | Fusobacterium nucleatum | tumor development in the colon | Several bacterial populations, including Escherichia coli, Bacteroides fragilis, and Fusobacterium nucleatum, have been shown to directly influence tumor development in the colon. | relate | What is the relationship between Fusobacterium nucleatum and tumor development in the colon? |
265 | Ruminococcus bromii | obesity | Coprococcus catus, Blautia hydrogenotrophic, Ruminococcus bromii, Ruminococcus obeum, and Eubacterium ventriosum were significantly correlated with obesity in Japanese people [60,61,62], whereas the presence of Bacteroides thetaiotaomicron, Bacteroides faecichinchillae, Flavonifractor plautii, Blautiawexlerae, and Clos... | relate | What is the relationship between Ruminococcus bromii and obesity? |
266 | Akkermansia muciniphila | Crohn?s disease | For example, 2 of the microorganisms on our panel, Escherichia-Shigella and Ruminococcus, are associated with Crohn?s disease, while 5 other organisms, Akkermansia muciniphila, Bifidobacterium, Dialister invisus, Odoribacter and Roseburia, are inversely associated with Crohn?s disease (Fig 5, S2 Table). | negative | What is the relationship between Akkermansia muciniphila and Crohn?s disease? |
267 | Bifidobacterium | irritable bowel syndrome | One meta?analysis, published in 2017, identified downregulated colonisation of Lactobacillus, Bifidobacterium and Faecalibacterium prausnitzii in patients with irritable bowel syndrome, particularly in irritable bowel syndrome where diarrhoea predominated. | negative | What is the relationship between Bifidobacterium and irritable bowel syndrome? |
268 | HP | Clostridioides difficile infection | Microbes from the genera Roseburia and Enterobacter were related to Helicobacter pylori (HP) in gastritis and Clostridioides difficile infection (CDI) in IBD. | relate | What is the relationship between HP and Clostridioides difficile infection? |
269 | Bacteroides fragilis | colon cancer | There are papers showing some microbes associated with GI tumors (Table 1), and common examples of microbes involved in cancer include Helicobacter pylori, which is associated with gastric cancer, Clonorchis sinensis and Opisthorchis viverrini, which are associated with bile duct cancer, and enterotoxigenic Bacteroides... | relate | What is the relationship between Bacteroides fragilis and colon cancer? |
270 | Clostridium | CD | Specifically, reduction of Clostridium cluster IV and XIV members has been proposed to contribute to dysbiosis in patients with CD,30 31 and selected mixtures of corresponding clostridia strains were shown to induce T regulatory cells with disease-suppressive phenotypes in IBD-related mouse models.32 These results supp... | negative | What is the relationship between Clostridium and CD? |
271 | Methanobrevibacter smithii | IBD | A recent human study has shown a reverse association between Methanobrevibacter smithii bacterial load and susceptibility to IBD, and this association could be extended to IBD patients in remission . | negative | What is the relationship between Methanobrevibacter smithii and IBD? |
272 | Veillonella | Crohn?s disease | To this regard, it has been reported that an increased amount of Veillonella is associated with higher levels of gut inflammation and the development of colitis and Crohn?s disease; on the contrary, an increased the abundance of the Prevotella genus has been described as a shield against inflammation and non-infectious... | positive | What is the relationship between Veillonella and Crohn?s disease? |
273 | Streptococcus | cholangitis | It was also observed that oral cavity and respiratory tract microorganisms were more prevalent than intestinal microorganisms in the microbiota of the common bile duct of gallstone disease patients or that the genera Prevotella, Streptococcus, Veillonella, Fusobacterium, and Haemophilus are prevalent in the bile microb... | relate | What is the relationship between Streptococcus and cholangitis? |
274 | Propionibacterium acnes | NAFLD | Del Chierico et al.compared NAFLD, NASH, and obese pediatric patients with healthy controls and found that NAFLD patients had an increased abundance of Anaerococcus (Actinobacteria), Ruminococcus (Firmicutes), Peptoniphilus (Firmicutes), Dorea (Firmicutes), Bradyrhizobium (Proteobacteria), and Propionibacterium acnes (... | negative | What is the relationship between Propionibacterium acnes and NAFLD? |
275 | Blautia | HCC | The sequencing of 16S bacterial RNA showed in the stool of HCC patients increased abundance of Bacteroides, Ruminococcus, Enterococcus, Phascolarctobacterium, and Oscillospira and decreased abundance of Bifidobacteria and Blautia as compared with liver cirrhosis without HCC. | negative | What is the relationship between Blautia and HCC? |
276 | Streptococcus | diarrheic piglets | In this study, Lactobacillus and Streptococcus were found at lower levels in diarrheic piglets, which are consistent with the previous studies (Costa et al., 2012; Hermann-Bank et al., 2015). | negative | What is the relationship between Streptococcus and diarrheic piglets? |
277 | Clostridium | IBS | 34 Despite the complexity of the gut flora ecosystem, some commensal microorganisms have been significantly related to IBS, including increased Clostridium perfringens (or more diverse Clostridium spp. | relate | What is the relationship between Clostridium and IBS? |
278 | Clostridium | type 2 diabetes mellitus | Significantly reduced Clostridium bacteria in the gut microbiota is widely observed in high-fat diet treatment and type 2 diabetes mellitus patients (Larsen et al., 2010; Naseer et al., 2014), and type 2 diabetes is a known risk factor for AD pathogenesis (Ahtiluoto et al., 2010). | negative | What is the relationship between Clostridium and type 2 diabetes mellitus? |
279 | EHEC | hemolytic uremic syndrome | Enterohemorrhagic Escherichia coli (EHEC) is an enteric pathogen that colonizes the colon and causes outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) worldwide. | positive | What is the relationship between EHEC and hemolytic uremic syndrome? |
280 | Eikenella corrodens | OLP | [5] investigated microbial in OLP patients with non-erosive/asymptomatic lesions and found that bacterial counts for Capnocytophaga sputigena, Eikenella corrodens, Lactobacillus crispatus, Mobiluncus curtisii, Neisseria mucosa, Prevotella bivia, Prevotella intermedia, and S. agalactiae at the sites of OLP lesions are s... | positive | What is the relationship between Eikenella corrodens and OLP? |
281 | Enterobacteriacceae | ulcerative colitis | In addition, the Lactobacillus, Streptococcus and Pseudomanas counts were significantly decreased and that for Enterobacteriacceae was significantly increased in patients with ulcerative colitis. | positive | What is the relationship between Enterobacteriacceae and ulcerative colitis? |
282 | Fusobacterium nucleatum | CRC | Increased abundances of Streptococcus gallolyticus, Enterococcus faecalis, Bacteroides fragilis, Prevotella, Helicobacter, and Fusobacterium nucleatum and decreased probiotics like Lactobacilli and Bifidobacteria are detected in CRC patients by previous reporting [21, 22]. | negative | What is the relationship between Fusobacterium nucleatum and CRC? |
283 | Streptococcus | upper respiratory infection | Nasal microbiota compositions characterized by Moraxella, Streptococcus, or Haemophilus have been reported to be associated with upper respiratory infection (URI) [12] asthma [13], AOM [12], pneumonia, or bronchiolitis [14, 15]. | relate | What is the relationship between Streptococcus and upper respiratory infection? |
284 | Moraxella catarrhalis | otitis | Best-known Moraxella infections are produced by Moraxella catarrhalis, which causes respiratory infections, including pneumonia and otitis in human. | positive | What is the relationship between Moraxella catarrhalis and otitis? |
285 | Clostridium butyricum | neurological deficits | Furthermore, the butyric acid-producing probiotic Clostridium butyricum improved neurological deficits, reduced brain edema, attenuated neurodegeneration, and ameliorated BBB impairment (105), as well as improved spatial memory in mouse models of weight-drop impact head injury and cerebral ischemia, respectively (83). | negative | What is the relationship between Clostridium butyricum and neurological deficits? |
286 | Escherichia | colitis | By using animal models of experimental colitis (20) and arthritis (21), it was shown that Gram-negative bacteria, including Escherichia, reduced inflammation, possibly through the TLR2/IL-10 axis which results in the repression of the pro-inflammatory pathway (20), whereas Gram-positive bacteria such as Lactobacillus c... | negative | What is the relationship between Escherichia and colitis? |
287 | Paenibacillus | periodontitis | In periodontitis patients, four genera (Dysgonomonas, Paenibacillus, Mycoplasma, and Campylobacter) and five species (Porphyromonas endodontalis, Dysgonomonas wimpennyi, P. canis, Campylobacter gracilis, and Leptotrichia buccalis) were higher, and only one species (P. melaninogenica) was lower in the C+P+ group compare... | positive | What is the relationship between Paenibacillus and periodontitis? |
288 | Prevotella intermedia | periodontitis | For example, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, and Prevotella intermedia have traditionally been considered pathogenic bacteria contributing to periodontitis [5, 12, 13]. | positive | What is the relationship between Prevotella intermedia and periodontitis? |
289 | Streptococcus gallolyticus | CRC | The abundance of several microbes, such as Streptococcus gallolyticus, Fusobacterium, B. fragilis, Escherichia Shigella, Peptostreptococcus ten [167] were observed to be enriched in CRC patients versus control groups, while genera such as Bacteroides, Roseburia and Pseudomonas were significantly depleted in CRC patient... | positive | What is the relationship between Streptococcus gallolyticus and CRC? |
290 | Klebsiella pneumonia | gastric cancer | Moreover, apart from H. Pylori, reduction of different other bacteria like Streptococcus sinensis, Acinetobacter baumannii, Prevotella pallens, Klebsiella pneumonia, Lactobacillus colihominis, and Lachnospiraceae are also responsible for gastric cancer in the human [91][92][93]. | relate | What is the relationship between Klebsiella pneumonia and gastric cancer? |
291 | Bacillus subtilis | tumor | Again, in the setting of DMH-induced colon carcinogenesis, the probiotics Bacillus subtilis and Clostridium butyricum separately administered to cancer-induced mice significantly decreased tumor incidence and size, compared to injured mice not receiving probiotics. | negative | What is the relationship between Bacillus subtilis and tumor? |
292 | enterococcus | IBS | We also found an enrichment of the Firmicutes, Proteobacteria, and Actinobacteria phyla, where enterobacteria, enterococcus, Akkermancia, Alteromonas, and others play important roles in the pathophysiology of polygenic IBS patients, associated with SNPs in TLRs, IL18, IL23, and IL17, which can acts as a pro or anti-inf... | relate | What is the relationship between enterococcus and IBS? |
293 | Fusobacterium nucleatum | colorectal neoplasia | Finally, although no strong evidence has yet been found to indict a specific microbe in colonic carcinogenesis, a recent study found that Fusobacterium nucleatum was enriched in human colon cancer tissue, and suggested that the microbe might promote colorectal neoplasia progression through recruitment of proinflammator... | positive | What is the relationship between Fusobacterium nucleatum and colorectal neoplasia? |
294 | Streptococcus | GI disorders | Clostridium, Streptococcus, Chryseobacterium, Haemophilus, and Comamonas are involved in GI disorders, maternal inflammation, maternofetal immune activation, neonatal sepsis, bacteremia or meningitis, acute appendicitis, and childhood vaccination [38], [39], [40], [41], [42]. | relate | What is the relationship between Streptococcus and GI disorders? |
295 | F. prausnitzii | UC | Several of the observed differences between the IBD patients and HD were consistent with previous reports, such as the decreased abundance of F. prausnitzii and Eubacterium rectale in the microbiota of UC patients, and the increased abundance of Escherichia species, including Escherichia coli, in the CD microbiota. | negative | What is the relationship between F. prausnitzii and UC? |
296 | Escherichia coli | IBS | Greater levels of Escherichia coli and Klebsiella spp were found in all patients with IBS. | relate | What is the relationship between Escherichia coli and IBS? |
297 | Streptococcus | AV | Escherichia coli, Streptococcus spp., Staphylococcus aureus, coagulase-negative staphylococci, Staphylococcus epidermidis, and Enterococcus faecalis have been found to colonize in significant numbers in AV patients. | positive | What is the relationship between Streptococcus and AV? |
298 | Clostridium difficile | diarrhea | Clostridium difficile is the most common cause of antibiotic?associated diarrhea, leading to high morbidity and mortality in cancer patients. | positive | What is the relationship between Clostridium difficile and diarrhea? |
299 | Fusobacterium nucleatum | chronic periodontitis | The results of our study confirmed this association, and showed that this Gram-negative rod was isolated from 68% of patients with chronic periodontitis, but its participation in the microbiota was very reduced, always smaller than others pathogens like Prevotella intermedia, Porphyromonas gingivalis and particularly F... | relate | What is the relationship between Fusobacterium nucleatum and chronic periodontitis? |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.